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clinical ultrasound

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https://www.readbyqxmd.com/read/29684498/multi-modal-characterization-of-vasculature-and-nanoparticle-accumulation-in-five-tumor-xenograft-models
#1
Einar Sulheim, Jana Kim, Annemieke van Wamel, Eugene Kim, Sofie Snipstad, Igor Vidic, Ingeborg Hovde Grimstad, Marius Widerøe, Sverre H Torp, Steinar Lundgren, David J Waxman, Catharina de Lange Davies
Preclinical research has demonstrated that nanoparticles and macromolecules can accumulate in solid tumors due to the enhanced permeability and retention effect. However, drug loaded nanoparticles often fail to show increased efficacy in clinical trials. A better understanding of how tumor heterogeneity affects nanoparticle accumulation could help elucidate this discrepancy and help in patient selection for nanomedicine therapy. Here we studied five human tumor models with varying morphology and evaluated the accumulation of 100 nm polystyrene nanoparticles...
April 20, 2018: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/29683996/biliary-drainage-in-patients-with-failed-ercp-percutaneous-versus-eus-guided-drainage
#2
Félix I Téllez-Ávila, David Herrera-Mora, Gilberto Duarte-Medrano, Gustavo Lopez-Arce, Dayana Lindoro-Barraza, Iván Casanova, Javier Elizondo-Rivera, Miguel Ramírez-Luna, Francisco Valdovinos-Andraca
AIM: The goal of the study is to compare the efficacy and safety of bile duct drains guided by endoscopic ultrasound-guided biliary drainage (EGBD) versus percutaneous transhepatic biliary drainage (PTBD). MATERIALS AND METHODS: Retrospective comparative study. Patients with obstruction of the bile duct who underwent the EGBD or PTBD procedure and had at least 1 previous endoscopic retrograde cholangiopancreatography that failed or was inaccessible to the second duodenal portion were included...
April 21, 2018: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/29683984/effects-of-progressive-addition-lens-wear-on-digital-work-in-pre-presbyopes
#3
Chea-Su Kee, Tsz Wing Leung, Ka-Hung Kan, Christie Hang-I Lam
SIGNIFICANCE: Growing popularity of handheld digital devices imposes significant challenges to our visual system and clinical management. This study aimed to determine the effects of lens design on parameters that may influence the refractive management of pre-presbyopic adult computer users. PURPOSE: To determine the effects of wearing conventional single-vision lenses (SVL) versus progressive addition lenses (PAL) on the working distance and refractive status...
April 20, 2018: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/29683909/acog-committee-opinion-no-734-the-role-of-transvaginal-ultrasonography-in-evaluating-the-endometrium-of-women-with-postmenopausal-bleeding
#4
(no author information available yet)
Cancer of the endometrium is the most common type of gynecologic cancer in the United States. Vaginal bleeding is the presenting sign in more than 90% of postmenopausal women with endometrial carcinoma. Clinical risk factors for endometrial cancer, including but not limited to age, obesity, use of unopposed estrogen, specific medical comorbidities (eg, polycystic ovary syndrome, type 2 diabetes mellitus, atypical glandular cells on screening cervical cytology), and family history of gynecologic malignancy also should be considered when evaluating postmenopausal bleeding...
May 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29683904/acog-committee-opinion-no-734-summary-the-role-of-transvaginal-ultrasonography-in-evaluating-the-endometrium-of-women-with-postmenopausal-bleeding
#5
(no author information available yet)
Cancer of the endometrium is the most common type of gynecologic cancer in the United States. Vaginal bleeding is the presenting sign in more than 90% of postmenopausal women with endometrial carcinoma. Clinical risk factors for endometrial cancer, including but not limited to age, obesity, use of unopposed estrogen, specific medical comorbidities (eg, polycystic ovary syndrome, type 2 diabetes mellitus, atypical glandular cells on screening cervical cytology), and family history of gynecologic malignancy also should be considered when evaluating postmenopausal bleeding...
May 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29683822/the-brachiocephalic-vein-as-a-safe-and-viable-alternative-to-internal-jugular-vein-for-central-venous-cannulation
#6
Paolo Federico Beccaria, Simona Silvetti, Rosalba Lembo, Giovanni Landoni, Giacomo Monti, Massimo Zambon, Daniela Mamo, Alberto Zangrillo
BACKGROUND: Although many studies have compared success and complication rates for central line insertion sites with and without ultrasound, few have examined the use of the brachiocephalic vein for central venous access. The aim of this study was to describe the brachiocephalic vein as an alternative site for elective ultrasound vascular cannulation in adults, and to compare it with the more commonly used internal jugular vein site in terms of procedural difficulties, first pass failure rate, overall failure rate, and safety...
April 19, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29683524/fetal-sex-determination-in-twin-pregnancies-using-cell-free-fetal-dna-analysis
#7
Miguel Milan, Emilia Mateu, David Blesa, Monica Clemente-Ciscar, Carlos Simon
OBJECTIVE(S): We sought to develop an accurate sex classification method in twin pregnancies using data obtained from a standard commercial non-invasive prenatal test. STUDY DESIGN: A total of 706 twin pregnancies were included in this retrospective analytical data study. Normalized chromosome values for chromosomes X and Y were used and adapted into a sex-score to predict fetal sex in each fetus and results were compared to the clinical outcome at birth. RESULTS: Outcome information at birth for sex chromosomes was available for 232 twin pregnancies...
April 23, 2018: Prenatal Diagnosis
https://www.readbyqxmd.com/read/29683433/a-case-of-symptomatic-popliteal-vein-aneurysm
#8
Roberta Garbuglio, Davide Turchino, Anna Maria Giribono, Luca Del Guercio, Umberto Marcello Bracale
We describe a case of a 44 year-old man with a subcutaneous swelling in the left popliteal fossa. The patient complained pain posteriorly to the left knee since several months and presented with a saccular aneurysm of the left popliteal vein (PVA) with reflux clearly evidenced at duplex ultrasound scan (DUS), but in absence of thrombus inside and without clinical signs of embolism. The patient was treated surgically by aneurysmectomy with lateral venorrhaphy according to Aldridge technique and a duplex ultrasound scan after six months revealed a complete patency of the left popliteal vein...
April 20, 2018: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/29682549/preliminary-exploration-of-epidemiologic-and-hemodynamic-characteristics-of-restrictive-filling-diastolic-dysfunction-based-on-echocardiography-in-critically-ill-patients-a-retrospective-study
#9
Yi Li, Wanhong Yin, Yao Qin, Xueying Zeng, Tongjuan Zou, Xiaoting Wang, Yangong Chao, Lina Zhang, Yan Kang, Chinese Critical Ultrasound Study Group Ccusg
Objective: To preliminarily describe the epidemiologic and hemodynamic characteristics of critically ill patients with restrictive filling diastolic dysfunction based on echocardiography. Setting: A retrospective study. Methods: Epidemiologic characteristics of patients with restrictive filling diastolic dysfunction in ICU were described; clinical and hemodynamic data were preliminarily summarized and compared between patients with and without restrictive filling diastolic dysfunction; most of the data were based on echocardiography...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29682535/the-role-of-mirna-132-against-apoptosis-and-oxidative-stress-in-heart-failure
#10
Xuelei Liu, Zhou Tong, Keyan Chen, Xiaofang Hu, Hongxu Jin, Mingxiao Hou
Objective: To explore the effect of microRNA-132 of heart failure and provide theoretical guidance for clinical treatment of heart failure (HF). Methods: Peripheral blood was collected from HF patients. RT-qPCR was used to determine microRNA-132 expression. Mouse models of heart failure were established. Color Doppler ultrasound was utilized to measure the changes of cardiac function. HE and Masson staining were applied to observe pathological changes of the myocardium...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29682435/assessment-of-ventriculoperitoneal-shunt-function-using-ultrasound-characterization-of-valve-interface-oscillation-as-a-proxy
#11
April Aralar, Matthew Bird, Robert Graham, Beomseo Koo, Parag Chitnis, Siddhartha Sikdar, Mahesh Shenai
Objective Ventricular shunts are a mainstay of hydrocephalus treatment, but the detection of its clinical failure often relies on circumstantial evidence. A direct, non-interventional method for reliably evaluating cerebrospinal fluid (CSF) function does not exist due to the difficulty of measuring in vivo flow characteristics. The objective of this study is to apply a novel method of ultrasound monitoring to characterize the oscillation observed during pulsatile CSF flow and failure states in an in vitro and cadaveric model...
February 19, 2018: Curēus
https://www.readbyqxmd.com/read/29682014/neurosurgical-interventions-for-occipital-encephalocele
#12
Lal Rehman, Ghulam Farooq, Irum Bukhari
Aims and Objectives: The aim of this study is to find the outcome of repair and resection of the occipital encephalocele. Study Design: Case series. Materials and Methods: The clinical data of fifty consecutive occipital encephalocele patients were retrieved from medical records including operative notes, postoperative follow-up visits, and postsurgical complications were noted for analysis from November 2009 to November 2013 at the Department of Neurosurgery, Jinnah Postgraduate Medical Centre, Karachi, Pakistan...
April 2018: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29681696/technique-of-antireflux-procedure-without-creating-submucosal-tunnel-for-surgical-correction-of-vesicoureteric-reflux-during-bladder-closure-in-exstrophy
#13
Kanoujia Sunil, Archika Gupta, Digamber Chaubey, Anand Pandey, Shiv Narain Kureel, Ajay Kumar Verma
Aim: To report the clinical application of the new surgical technique of antireflux procedure without creating submucosal tunnel for surgical correction of vesicoureteric reflux during bladder closure in exstrophy. Materials and Methods: Based on the report of published experimental technique, the procedure was clinically executed in seven patients of classic exstrophy bladder with small bladder plate with polyps, where the creation of submucosal tunnel was not possible, in last 18 months...
April 2018: Journal of Indian Association of Pediatric Surgeons
https://www.readbyqxmd.com/read/29681508/diagnosis-of-ovarian-torsion-is-it-time-to-forget-about-doppler
#14
Gilat L Grunau, Alison Harris, Jean Buckley, Nicole J Todd
OBJECTIVE: Accuracy of ultrasound in diagnosis of ovarian torsion remains controversial, with some studies reporting correct diagnosis in only 23% to 66% of cases. Normal Doppler flow does not necessarily exclude an ovarian torsion; in fact, it may lead to missing the diagnosis and has been show to delay management. The objective of our study was to assess sensitivity and specificity of ultrasound diagnosis of ovarian torsion and to analyze the factors contributing to correct and incorrect diagnosis...
April 19, 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29681446/reduction-of-radiography-with-point-of-care-elbow-ultrasonography-for-elbow-trauma-in-children
#15
Julia Tokarski, Jeffrey R Avner, Joni E Rabiner
OBJECTIVES: To determine whether point-of-care elbow ultrasound (US), with history and physical examination, can decrease radiography for patients with elbow trauma. Secondary outcomes included evaluation of pediatric emergency department (PED) length of stay (LOS) and test performance characteristics. STUDY DESIGN: This was a prospective study of patients up to age 21 years with elbow trauma necessitating radiography. After clinical examination and before radiography, pediatric emergency physicians performed elbow ultrasonography of the posterior fat pad and determined whether radiography was required...
April 19, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29681423/ultrasonic-cavitation-enabled-treatment-for-therapy-of-hypertrophic-cardiomyopathy-proof-of-principle
#16
Douglas L Miller, Xiaofang Lu, Chunyan Dou, Yiying I Zhu, Rachael Fuller, Kristina Fields, Mario L Fabiilli, Gabe E Owens, David Gordon, Oliver D Kripfgans
Ultrasound myocardial cavitation-enabled treatment was applied to the SS-16BN rat model of hypertrophic cardiomyopathy for proof of the principle underlying myocardial reduction therapy. A focused ultrasound transducer was targeted using 10-MHz imaging (10 S, GE Vivid 7) to the left ventricular wall of anesthetized rats in a warmed water bath. Pulse bursts of 4-MPa peak rarefactional pressure amplitude were intermittently triggered 1:8 heartbeats during a 10-min infusion of a microbubble suspension. Methylprednisolone was given to reduce initial inflammation, and Losartan was given to reduce fibrosis in the healing tissue...
April 19, 2018: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/29680409/-usefulness-of-early-lung-ultrasound-in-acute-mild-moderate-acute-bronchiolitis-a-pilot-study
#17
Elia Zoido Garrote, Cristina García Aparicio, Constanza Camila Torrez Villarroel, Antonio Pedro Vega García, Manoel Muñiz Fontán, Ignacio Oulego Erroz
OBJECTIVE: To determine the correlation between the findings seen in early lung ultrasound with the clinical severity scales, and its association with the subsequent progression of the mild-moderate acute bronchiolitis (AB). PATIENTS AND METHODS: An observational prospective study conducted on infants with mild-moderate BA, using lung ultrasound in the first 24hours of hospital care. The lung involvement was graded (range 0-50 points) based on an ultrasound score (ScECO) and 2routinely used clinical scales: the modified Wood Downes Ferres (WDFM), and the Hospital Sant Joan de Deu (HSJD)...
April 18, 2018: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/29680384/treatment-of-solid-tumors-in-dogs-using-veterinary-high-intensity-focused-ultrasound-a-retrospective-clinical-study
#18
M-O Ryu, S-H Lee, J-O Ahn, W-J Song, Q Li, H-Y Youn
High-intensity focused ultrasound (HIFU) is a cancer treatment tool that focuses ultrasound energy on tumor tissues, which initiates necrosis via heat and mechanical effects. The efficacy of veterinary HIFU (vHIFU) was evaluated for the treatment of solid tumors in dogs. Data from 11 client-owned dogs with various solid tumors treated by vHIFU between 2013 and 2017 were retrospectively evaluated. Ten of the 11 dogs were followed up; clinical signs were alleviated in five. Four dogs exhibited a decrease in tumor size, and bleeding stopped in all four dogs with hemorrhagic tumors...
April 2018: Veterinary Journal
https://www.readbyqxmd.com/read/29680297/early-results-of-percutaneous-arteriovenous-fistula-creation-with-the-ellipsys-vascular-access-system
#19
Alexandros Mallios, William C Jennings, Benoit Boura, Alessandro Costanzo, Pierre Bourquelot, Myriam Combes
OBJECTIVE: We reviewed our initial experience creating a percutaneous arteriovenous fistula (pAVF) using a thermal resistance anastomosis device with proximal radial artery inflow. METHODS: A retrospective review was conducted of all patients who underwent a pAVF creation procedure between May 2017 and October 2017. Primary end points of the study were technical success, patency by Doppler ultrasound examination or angiography, flow levels achieved, time to first use, and pAVF-related complications...
April 18, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29679518/new-insights-in-the-use-of-pleural-ultrasonography-for-diagnosis-and-treatment-of-pleural-disease
#20
Giampietro Marchetti, Sabrina Arondi, Francesca Baglivo, Sara Lonni, Federico Quadri, Alberto Valsecchi, Nicola Venturoli, Paolo Ceruti
The use of transthoracic ultrasound has acquired a wide consensus among respiratory physicians during the last few years. The developing of portable and easily available devices favorites patient's bedside evaluation. Transthoracic ultrasound provides rapid, real-time and low-cost diagnostic information, allowing image-guided chest interventions and reducing procedural risks. The different acoustic impedance between aerated and not aerated organs produces artifacts known as A lines, B lines, sliding sign, lung point, etc...
April 21, 2018: Clinical Respiratory Journal
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