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https://www.readbyqxmd.com/read/29452427/effect-of-routine-screening-head-ultrasounds-on-clinical-interventions-for-premature-infants
#1
Andrew Z Heling, Matthew M Laughon, Wayne A Price
OBJECTIVE: This article assesses whether routine, screening head ultrasound (HUS) studies performed at 7 to 14 postnatal days for premature infants are followed by clinical interventions. STUDY DESIGN: This retrospective cohort study included all inborn infants delivered at < 30 weeks' gestational age (GA) between January 1, 2012 and December 31, 2015 at a single center who had a routine, screening HUS performed between 7 and 14 postnatal days ( n = 303). We defined "clinical intervention" as a 7 to 14 postnatal day HUS that was followed by neurosurgical intervention prior to a 36- to 40-week postmenstrual age (PMA) HUS or elective withdrawal of critical care within 30 days of a positive HUS finding...
February 16, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29452275/a-laser-activated-multifunctional-targeted-nanoagent-for-imaging-and-gene-therapy-in-a-mouse-xenograft-model-with-retinoblastoma-y79-cells
#2
Mingxing Wu, Haibo Xiong, Hongmi Zou, Meng Li, Pan Li, Yu Zhou, Yan Xu, Jia Jian, Fengqiu Liu, Hongyun Zhao, Zhigang Wang, Xiyuan Zhou
Retinoblastoma (RB) is the most common intraocular malignancy of childhood that urgently needs early detection and effective therapy methods. The use of nanosized gene delivery systems is appealing because of their highly adjustable structure to carry both therapeutic and imaging agents. Herein, we report a folic acid (FA)-modified phase-changeable cationic nanoparticle encapsulating liquid perfluoropentane (PFP) and indocyanine green (ICG) (FA-CN-PFP-ICG, FCNPI) with good plasmid DNA (pDNA) carrying capacity, favorable biocompatibility, excellent photoacoustic (PA) and ultrasound (US) contrast, enhanced gene transfection efficiency and therapeutic effect...
February 13, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29452209/prolactin-improves-hepatic-steatosis-via-cd36-pathway
#3
Pengzi Zhang, Zhijuan Ge, Hongdong Wang, Wenhuan Feng, Xitai Sun, Xuehui Chu, Can Jiang, Yan Wang, Dalong Zhu, Yan Bi
BACKGROUND & AIMS: Prolactin (PRL) is a multifunctional polypeptide with effects on metabolism; however, little is known about its effect on hepatic steatosis and lipid metabolism. METHODS: The serum PRL levels of 456 non-alcoholic fatty liver disease (NAFLD) patients and 403 non-NAFLD controls diagnosed by ultrasound, and 85 subjects with liver histology obtained during metabolic surgery (44 female and 30 male NAFLD patients and 11 age-matched non-NAFLD female subjects) were evaluated...
February 13, 2018: Journal of Hepatology
https://www.readbyqxmd.com/read/29451774/organic-semiconducting-photoacoustic-nanodroplets-for-laser-activatable-ultrasound-imaging-and-combinational-cancer-therapy
#4
Wei Tang, Zhen Yang, Sheng Wang, Zhantong Wang, Jibin Song, Guocan Yu, Wenpei Fan, Yunlu Dai, Jingjing Wang, Lingling Shan, Gang Niu, Quli Fan, Xiaoyuan Chen
Combination of photoacoustic (PA) and ultrasound (US) imaging offers high spatial resolution images with deep tissue penetration, which shows great potentials in applications in medical imaging. Development of PA/US dual-contrast agents with high contrast and excellent biocompatible is of great interest. Herein, an organic semiconducting photoacoustic nanodroplet, PS-PDI-PAnD, is developed by stabilizing low-boiling-point perfluorocarbon (PFC) droplet with a photoabsorber and photoacoustic agent of perylene diimide (PDI) molecules and co-encapsulating the droplet with photosensitizers of ZnF16Pc molecules...
February 16, 2018: ACS Nano
https://www.readbyqxmd.com/read/29451124/copper-oxide-loaded-plga-nanospheres-towards-a-multifunctional-nanoscale-platform-for-ultrasound-based-imaging-and-therapy
#5
Or Perlman, Iris S Weitz, Sarit Sivan, Hiba Abu-Khalla, Madeleine Benguigui, Yuval Shaked, Haim Azhari
Copper oxide nanoparticles (CuO-NPs) are increasingly investigated for diagnostic and therapeutic purposes. Recent work have demonstrated their anticancer potential as well as contrast agent capabilities for magnetic resonance imaging (MRI) and through-transmission ultrasound. However, no capabilities of CuO-NPS were demonstrated using conventional ultrasound systems, which, unlike the formers, are widely deployed in the clinic. Furthermore, in spite of their potential as multifunctional nano-based materials for diagnosis and therapy, CuO-NPs were delayed from further clinical translation due to their inherent toxicity...
February 16, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29450905/a-tramp-derived-orthotopic-prostate-syngeneic-tops-cancer-model-for-investigating-anti-tumor-treatments
#6
Justin Lardizabal, Jun Ding, Zahid Delwar, Paul S Rennie, William Jia
BACKGROUND: Patients with advanced prostate cancer have limited curative options, therefore new treatments are needed. Mouse models play a pivotal role in the discovery and development of new treatments. In the present study, a TRAMP-derived Orthotopic Prostate Syngeneic (TOPS) mouse model was developed and found to provide a consistent means of monitoring tumor and metastatic responses to novel treatments. METHODS: The mouse TOPS model was generated using luciferase transduced TRAMP-C2 prostate cancer cells that were orthotopically injected into Bl6 mice by ultrasound guidance...
February 16, 2018: Prostate
https://www.readbyqxmd.com/read/29450884/is-sonographically-measured-cervical-length-at-37-weeks-gestation-associated-with-intrapartum-cesarean-section-a-prospective-cohort-study
#7
Bradley de Vries, Rajit Narayan, Kevin McGeechan, Stanley Santiagu, Ramesh Vairavan, Minke Burke, Hala Phipps, Jon Hyett
Cesarean section rates continue to increase globally. Prediction of intrapartum cesarean section could lead to preventative measures. Our aim was to assess the association between sonographically measured cervical length at 37 weeks' gestation and cesarean section among women planning a vaginal birth. The population was women with a low risk pregnancy or with gestational diabetes MATERIAL AND METHODS: This was a prospective cohort study conducted in a tertiary referral hospital in Sydney, Australia. 212 women with a low risk pregnancy or with gestational diabetes were recruited including 158 nulliparous and 54 parous women...
February 16, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29450853/endometriosis-clinical-features-mr-imaging-findings-and-pathologic-correlation
#8
REVIEW
Pietro Valerio Foti, Renato Farina, Stefano Palmucci, Ilenia Anna Agata Vizzini, Norma Libertini, Maria Coronella, Saveria Spadola, Rosario Caltabiano, Marco Iraci, Antonio Basile, Pietro Milone, Antonio Cianci, Giovanni Carlo Ettorre
OBJECTIVE: We illustrate the magnetic resonance imaging (MRI) features of endometriosis. BACKGROUND: Endometriosis is a chronic gynaecological condition affecting women of reproductive age and may cause pelvic pain and infertility. It is characterized by the growth of functional ectopic endometrial glands and stroma outside the uterus and includes three different manifestations: ovarian endometriomas, peritoneal implants, deep pelvic endometriosis. The primary locations are in the pelvis; extrapelvic endometriosis may rarely occur...
February 15, 2018: Insights Into Imaging
https://www.readbyqxmd.com/read/29450615/contrast-enhanced-ultrasound-ceus-in-abdominal-intervention
#9
REVIEW
Dean Y Huang, Gibran T Yusuf, Mohammad Daneshi, Raymond Ramnarine, Annamaria Deganello, Maria E Sellars, Paul S Sidhu
The introduction of ultrasound contrast agents has rendered contrast-enhanced ultrasound (CEUS) a valuable complementary technique to address clinically significant problems. This pictorial review describes the use of CEUS guidance in abdominal intervention and illustrates such application for a range of clinical indications. Clinical application of CEUS discussed include commonly performed abdominal interventional procedures, such as biopsy, drainage, nephrostomy, biliary intervention, abdominal tumor ablation and its subsequent monitoring, and imaging of vascular complications following abdominal intervention...
February 15, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29450530/screening-for-ovarian-cancer-updated-evidence-report-and-systematic-review-for-the-us-preventive-services-task-force
#10
Jillian T Henderson, Elizabeth M Webber, George F Sawaya
Importance: Ovarian cancer is relatively rare but the fifth-leading cause of cancer mortality among United States women. Objective: To systematically review evidence on benefits and harms of ovarian cancer screening among average-risk women to inform the United States Preventive Services Task Force. Data Sources: MEDLINE, PubMed, Cochrane Collaboration Registry of Controlled Trials; studies published in English from January 1, 2003, through January 31, 2017; ongoing surveillance in targeted publications through November 22, 2017...
February 13, 2018: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29449283/clinical-validation-of-a-predictive-model-for-the-presence-of-cervical-lymph-node-metastasis-in-papillary-thyroid-cancer
#11
N U Patel, K E Lind, K McKinney, T J Clark, S S Pokharel, J M Meier, E R Stamm, K Garg, B Haugen
BACKGROUND AND PURPOSE: Ultrasound is a standard technique to detect lymph node metastasis in papillary thyroid cancer. Cystic changes and microcalcifications are the most specific features of metastasis, but with low sensitivity. This prospective study compared the diagnostic accuracy of a predictive model for sonographic evaluation of lymph nodes relative to the radiologist's standard assessment in detecting papillary thyroid cancer metastasis in patients after thyroidectomy. MATERIALS AND METHODS: Cervical lymph node sonographic images were reported by a radiologist (R method) per standard practice...
February 15, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29449196/clinical-predictors-of-successful-vaginal-myomectomy-for-prolapsed-pedunculated-uterine-leiomyoma
#12
Serdar Aydın, Hale Göksever Çelik, Mustafa Maraşlı, Rabia Zehra Bakar
OBJECTIVE: Uterine leiomyomas are the most common pelvic tumor in women. The calculated prevalence of prolapsed pedunculated leiomyoma was 2.5% in patients who underwent surgery. Although vaginal removal is safe and effective, hysterectomy demand is questionable. We aimed to analyze the association between patient characteristics, clinical features of prolapsed pedunculated submucosal leiomyoma and the probability of successful vaginal myomectomy. MATERIALS AND METHODS: This study was conducted in 35 women who presented with prolapsed pedunculated uterine leiomyoma...
February 1, 2018: Journal of the Turkish German Gynecological Association
https://www.readbyqxmd.com/read/29449144/a-dynamic-graph-cuts-method-with-integrated-multiple-feature-maps-for-segmenting-kidneys-in-2d-ultrasound-images
#13
Qiang Zheng, Steven Warner, Gregory Tasian, Yong Fan
RATIONALE AND OBJECTIVES: Automatic segmentation of kidneys in ultrasound (US) images remains a challenging task because of high speckle noise, low contrast, and large appearance variations of kidneys in US images. Because texture features may improve the US image segmentation performance, we propose a novel graph cuts method to segment kidney in US images by integrating image intensity information and texture feature maps. MATERIALS AND METHODS: We develop a new graph cuts-based method to segment kidney US images by integrating original image intensity information and texture feature maps extracted using Gabor filters...
February 12, 2018: Academic Radiology
https://www.readbyqxmd.com/read/29447724/no-127-the-evaluation-of-stress-incontinence-prior-to-primary-surgery
#14
Scott A Farrell
OBJECTIVE: To provide clinical guidelines for the evaluation of women with stress urinary incontinence prior to primary anti-incontinence surgery. OPTIONS: The modalities of evaluation range from basic pelvic examination through to the use of adjuncts including ultrasound and urodynamic testing. OUTCOMES: These guidelines provide a comprehensive approach to the preoperative evaluation of urinary incontinence to ensure that excessive evaluation is avoided without sacrificing diagnostic accuracy...
February 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29447720/no-257-ultrasonographic-cervical-length-assessment-in-predicting-preterm-birth-in-singleton-pregnancies
#15
Kenneth Lim, Kimberly Butt, Joan M Crane
OBJECTIVES: To review (1) the use of ultrasonographic-derived cervical length measurement in predicting preterm birth and (2) interventions associated with a short cervical length. OUTCOMES: Reduction in rates of prematurity and/or better identification of those at risk, as well as possible prevention of unnecessary interventions. EVIDENCE: Published literature was retrieved through searches of PubMed and The Cochrane Library up to December 2009, using appropriate controlled vocabulary and key words (preterm labour, ultrasound, cervix, incompetent cervix, transvaginal, transperineal, cervical length, fibronectin)...
February 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29447020/effect-of-pretreatment-with-gonadotropin-releasing-hormone-analog-gnrh-%C3%AE-on-high-intensity-focused-ultrasound-ablation-for-diffuse-adenomyosis-a-preliminary-study
#16
Xiao-Ying Zhang, Ying-Shu Guo, Jiu-Mei Chen, Jin-Juan Wang, Hong Ye, Chun-Yi Zang, Hua Duan
OBJECTIVES: To evaluate the efficacy and safety of GnRH-α pretreatment with HIFU ablation for diffuse adenomyosis. METHODS: From January 2014 to December 2016, 61 patients were divided into two groups. Twenty-three patients with larger uteri received pretreatment with GnRH-αand were then subjected to HIFU, and 38 patients underwent HIFU alone. The technical parameters included treatment time, sonication time, average sonication power, treatment intensity, total energy, non-perfusion volume (NPV) and NPV ratio...
February 15, 2018: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/29446113/use-of-a-simple-inexpensive-dual-modality-phantom-as-a-learning-tool-for-magnetic-resonance-imaging-ultrasound-fusion-techniques
#17
William R Walter, Christopher J Burke, Mamadou Diallo, Ronald S Adler
We describe an easily constructed, customizable phantom for magnetic resonance imaging-ultrasound fusion imaging and demonstrate its role as a learning tool to initiate clinical use of this emerging modality. Magnetic resonance imaging-ultrasound fusion can prove unwieldy to integrate into routine practice. We demonstrate real-time fusion with single-sequence magnetic resonance imaging uploaded to the ultrasound console. Phantom training sessions allow radiologists and sonographers to practice fiducial marker selection and improve efficiency with the fusion hardware and software interfaces...
February 15, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29445933/multimodality-imaging-of-subacromial-impingement-syndrome
#18
REVIEW
Lionel Pesquer, Sophie Borghol, Philippe Meyer, Mickael Ropars, Benjamin Dallaudière, Pierre Abadie
Subacromial impingement syndrome results from irritation of the tendons of the rotator cuff muscles in the subacromial space and may manifest as a range of pathologies. However, subacromial impingement is a dynamic condition for which imaging reveals predisposing factors but no pathognomonic indicators. Also, the usual imaging features of subacromial impingement may be seen in symptomatic and asymptomatic patients. Therefore, imaging is able to detect tears and describe the risk factors of impingement but cannot confirm subacromial impingement...
February 14, 2018: Skeletal Radiology
https://www.readbyqxmd.com/read/29445433/upright-catheter-based-cerebral-angiography
#19
Adnan I Qureshi, Muhammad A Saleem, Omer Naveed, Mohtasim A Qureshi, Shawn S Wallery
Background: Several studies using Doppler ultrasound have suggested cerebral venous drainage is through paravertebral venous plexus due to the collapse of internal jugular veins in an upright position. Methods: We present a technique of acquiring venographic images during an upright position as part of catheter-based angiography to provide additional information regarding cerebral venous diseases. Angiographic images in anteroposterior projection were acquired in lying position and after patients were placed at 60° using radiolucent supporting wedges on angiographic table...
December 2017: Journal of Vascular and Interventional Neurology
https://www.readbyqxmd.com/read/29445296/the-ultrasound-guided-retrolaminar-block-volume-dependent-injectate-distribution
#20
Marija Damjanovska, Tatjana Stopar Pintaric, Erika Cvetko, Kamen Vlassakov
Purpose: The ultrasound-guided retrolaminar block is one of the newer and simpler alternatives to the traditional, often technically challenging, paravertebral (PV) block. Its feasibility, safety, and efficacy have already been clinically demonstrated in patients with multiple rib fractures using higher volumes of local anesthetic, when compared with the traditional approach. The primary aim of this observational anatomical study was to assess the spread of local anesthetic from the retrolaminar injection point to the PV space and its volume dependence...
2018: Journal of Pain Research
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