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https://www.readbyqxmd.com/read/29221779/effect-of-sodium-oxybate-modafinil-and-their-combination-on-disrupted-nighttime-sleep-in-narcolepsy
#1
Yves Dauvilliers, Thomas Roth, Diane Guinta, Sarah Alvarez-Horine, Efim Dynin, Jed Black
OBJECTIVE: To assess the effects of three narcolepsy treatment modalities on sleep stage shifts associated with disrupted nighttime sleep (DNS) using data from a clinical trial. METHODS: Polysomnograms were reviewed from 155 patients (who had these data available at baseline and 8 weeks) of the 278 patients who were randomized to placebo, 9-g sodium oxybate (SXB)/nightly, 200-600 mg/d modafinil, or SXB + modafinil. Major outcomes of these post hoc analyses, analyzed using analysis of covariance, were change from baseline in number of shifts from Stages N2/3/rapid eye movement (REM) to Stage N1/Wake, and from Stage N1/Wake to REM...
December 2017: Sleep Medicine
https://www.readbyqxmd.com/read/29214039/clinical-and-genetic-analysis-of-spinocerebellar-ataxia-type-7-sca7-in-zambian-families
#2
Masharip Atadzhanov, Danielle C Smith, Mwila H Mwaba, Omar K Siddiqi, Alan Bryer, L Jacquie Greenberg
Background: To date, 43 types of Spinocerebellar Ataxias (SCAs) have been identified. A subset of the SCAs are caused by the pathogenic expansion of a CAG repeat tract within the corresponding gene. Ethnic and geographic differences are evident in the prevalence of the autosomal dominant SCAs. Few descriptions of the clinical phenotype and molecular genetics of the SCAs are available from the African continent. Established studies mostly concern the South African populations, where there is a high frequency of SCA1, SCA2 and SCA7...
2017: Cerebellum & Ataxias
https://www.readbyqxmd.com/read/29193320/contrast-balanced-binocular-treatment-in-children-with-deprivation-amblyopia
#3
Lisa M Hamm, Zidong Chen, Jinrong Li, Shuan Dai, Joanna Black, Junpeng Yuan, Minbin Yu, Benjamin Thompson
BACKGROUND: Children with deprivation amblyopia due to childhood cataract have been excluded from much of the emerging research into amblyopia treatment. An investigation was conducted to determine whether contrast-balanced binocular treatment - a strategy currently being explored for children with anisometropic and strabismic amblyopia - may be effective in children with deprivation amblyopia. METHODS: An unmasked, case-series design intended to assess proof of principle was employed...
November 28, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/29192095/health-effects-of-exposure-to-second-and-third-hand-marijuana-smoke-a-systematic-review
#4
Hannah Holitzki, Laura E Dowsett, Eldon Spackman, Tom Noseworthy, Fiona Clement
BACKGROUND: Recreational marijuana has been legalized in 11 jurisdictions; Canada will legalize marijuana by July 2018. With this changing landscape, there is a need to understand the public health risks associated with marijuana to support patient-care provider conversations, harm-reduction measures and evidence-informed policy. The objective of this work was to summarize the health effects of exposure to second- and third-hand marijuana smoke. METHODS: In this systematic review, we searched 6 databases from inception to October 2017...
November 24, 2017: CMAJ Open
https://www.readbyqxmd.com/read/29183045/peripapillary-microvascular-improvement-and-lamina-cribrosa-depth-reduction-after-trabeculectomy-in-primary-open-angle-glaucoma
#5
Joong Won Shin, Kyung Rim Sung, Ki Bang Uhm, Jaehyuck Jo, Yeji Moon, Min Kyung Song, Ji Yoon Song
Purpose: To evaluate peripapillary microvascular changes in patients with primary open-angle glaucoma (POAG) after trabeculectomy using optical coherence tomography (OCT) angiography, and to determine the influence of lamina cribrosa (LC) displacement on changes in peripapillary microvasculature. Methods: The peripapillary retinal microvasculature and LC were imaged using OCT angiography and OCT-enhanced depth imaging, respectively. The microvasculature and LC depth (LCD) were measured before, and 1 week, 1 month, and 3 months after trabeculectomy...
November 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29182401/the-association-of-cataract-and-lens-epithelial-cell-apoptosis-in-patients-with-pseudoexfoliation-syndrome
#6
Pembe Oltulu, Refik Oltulu
PURPOSE: The aim of this study was to measure the density of apoptotic lens epithelial cells (LECs) and to determine its association with cataract formation in eyes with pseudoexfoliation syndrome (PEX). MATERIALS AND METHODS: Twenty-one eyes of 21 patients diagnosed with PEX without glaucoma (Group 1) and 22 eyes of 22 subjects without PEX (Group 2) were enrolled in this study. During cataract surgery, anterior capsule samples were obtained by the 5.5 mm continuous curvilinear capsulorhexis method...
November 28, 2017: Current Eye Research
https://www.readbyqxmd.com/read/29172343/clinical-challenges-q-a-29-black-eye
#7
Dimitrios Malamos, Crispian Scully
No abstract text is available yet for this article.
March 2017: Dental Update
https://www.readbyqxmd.com/read/29165496/fluorescence-quenching-based-signal-amplification-on-immunochromatography-test-strips-for-dual-mode-sensing-of-two-biomarkers-of-breast-cancer
#8
Bo Zhang, Wenjuan Ma, Fuxin Li, Weichen Gao, Qian Zhao, Weipan Peng, Jiafang Piao, Xiaoli Wu, Hanjie Wang, Xiaoqun Gong, Jin Chang
Recently, immunochromatography test strips (ICTS) have been fully developed for point-of-care testing (POCT). However, the intrinsic limitations including non-quantitative detection of colloidal gold ICTS and low sensitivity of fluorescence ICTS (FICTS) significantly restrict their further application in clinical diagnosis. Taking advantages of rapid colorimetric qualitative detection and fluorescence quantitation, we designed a kind of sensitive and dual-mode magnetic FICTS (mFICTS) based on PLGA@Fe3O4 super-paramagnetic nanosphere (SPMN) probes quenching multiplex fluorescer on the test line through sandwich immunoreactions...
November 22, 2017: Nanoscale
https://www.readbyqxmd.com/read/29141881/it-s-not-all-black-and-white-visual-scene-parameters-influence-optokinetic-reflex-performance-in-xenopus-laevis-tadpoles
#9
Céline M Gravot, Alexander G Knorr, Stefan Glasauer, Hans Straka
The maintenance of visual acuity during active and passive body motion is ensured by gaze-stabilizing reflexes that aim at minimizing retinal image slip. For the optokinetic reflex (OKR), large-field visual motion of the surround forms the essential stimulus that activates eye movements. Properties of the moving visual world influence cognitive motion perception and the estimation of visual image velocity. Therefore, the performance of brainstem-mediated visuo-motor behaviors might also depend on image scene characteristics...
November 15, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29120975/refractive-error-in-a-sample-of-black-high-school-children-in-south-africa
#10
Samuel Otabor Wajuihian, Rekha Hansraj
SIGNIFICANCE: This study focused on a cohort that has not been studied and who currently have limited access to eye care services. The findings, while improving the understanding of the distribution of refractive errors, also enabled identification of children requiring intervention and provided a guide for future resource allocation. PURPOSE: The aim of conducting the study was to determine the prevalence and distribution of refractive error and its association with gender, age, and school grade level...
November 9, 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/29118625/a-new-species-of-scinax-from-the-purus-madeira-interfluve-brazilian-amazonia-anura-hylidae
#11
Miquéias Ferrão, Jiří Moravec, Rafael de Fraga, Alexandre Pinheiro de Almeida, Igor Luis Kaefer, Albertina Pimentel Lima
A new tree frog species of the genus Scinax from the interfluve between the Purus and Madeira rivers, Brazilian Amazonia, is described and illustrated. The new species is diagnosed by medium body size, snout truncate in dorsal view, ulnar and tarsal tubercles absent, nuptial pads poorly developed, skin on dorsum shagreen, dorsum light brown with dark brown spots and markings, white groin with black spots, anterior and posterior surfaces of thighs black, and iris bright orange. The advertisement call consists of a single short note, with 16-18 pulses and dominant frequency at 1572-1594 Hz...
2017: ZooKeys
https://www.readbyqxmd.com/read/29095512/through-the-eyes-of-children-drawings-as-an-evaluation-tool-for-children-s-understanding-about-endangered-mexican-primates
#12
Montserrat Franquesa-Soler, Juan Carlos Serio-Silva
This study seeks to understand children's perceptions and knowledge of endangered Mexican primates. The black howler monkey (Alouatta pigra) is a charismatic species endemic to Southern Mexico, Northern Belize, and Guatemala and is a symbol of the region that fosters a sense of local pride. Therefore, it can be considered a flagship species for the forests of Southern Mexico. We evaluated the perception and knowledge that 297 Mexican elementary school children (8-10 years old) have about black howler monkeys...
November 2, 2017: American Journal of Primatology
https://www.readbyqxmd.com/read/29079993/auditory-display-as-feedback-for-a-novel-eye-tracking-system-for-sterile-operating-room-interaction
#13
David Black, Michael Unger, Nele Fischer, Ron Kikinis, Horst Hahn, Thomas Neumuth, Bernhard Glaser
PURPOSE: The growing number of technical systems in the operating room has increased attention on developing touchless interaction methods for sterile conditions. However, touchless interaction paradigms lack the tactile feedback found in common input devices such as mice and keyboards. We propose a novel touchless eye-tracking interaction system with auditory display as a feedback method for completing typical operating room tasks. Auditory display provides feedback concerning the selected input into the eye-tracking system as well as a confirmation of the system response...
October 27, 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/29069653/intraocular-pressure-spikes-within-first-postoperative-hours-following-standard-trabeculectomy-incidence-and-associated-factors
#14
Felipe Daher, Izabela Almeida, Michele Ushida, Bernardo Soares, Syril Dorairaj, Fabio N Kanadani, Augusto Paranhos, Carolina P B Gracitelli, Tiago S Prata
PURPOSE: To evaluate the incidence of intraocular pressure (IOP) spikes within the first postoperative hours following trabeculectomy (TRAB) and to determine possible associated factors. METHODS: An observational study was carried out. We enrolled consecutive patients undergoing standard TRAB with mitomycin C. They were examined twice within the first few postoperative hours (hours 1-2 and 4-6) and 3 times after TRAB (on days 1, 7, and 30). Demographic and ocular data were collected...
October 26, 2017: Ophthalmic Research
https://www.readbyqxmd.com/read/29065640/a-fast-svm-based-tongue-s-colour-classification-aided-by-k-means-clustering-identifiers-and-colour-attributes-as-computer-assisted-tool-for-tongue-diagnosis
#15
Nur Diyana Kamarudin, Chia Yee Ooi, Tadaaki Kawanabe, Hiroshi Odaguchi, Fuminori Kobayashi
In tongue diagnosis, colour information of tongue body has kept valuable information regarding the state of disease and its correlation with the internal organs. Qualitatively, practitioners may have difficulty in their judgement due to the instable lighting condition and naked eye's ability to capture the exact colour distribution on the tongue especially the tongue with multicolour substance. To overcome this ambiguity, this paper presents a two-stage tongue's multicolour classification based on a support vector machine (SVM) whose support vectors are reduced by our proposed k-means clustering identifiers and red colour range for precise tongue colour diagnosis...
2017: Journal of Healthcare Engineering
https://www.readbyqxmd.com/read/29060348/study-on-the-effects-of-brightness-contrast-on-steady-state-motion-visual-evoked-potential
#16
Wenqiang Yan, Guanghua Xu, Jun Xie, Min Li, Sicong Zhang, Ailing Luo
Traditional steady - state visual evoked potential (SSVEP) using light flicker stimulation may easy cause visual fatigue with a consequent reduction of recognition accuracy. In the previous study, we proposed a steady - state motion visual evoked potential (SSMVEP) brain - computer interface (BCI) method. A black - white ring - shaped checkerboard was used as the visual stimulus paradigm in this study. The movement patterns of the checkerboard included contraction and expansion. Based on the signal-to-noise ratio (SNR), recognition accuracy and anti-fatigue properties, the effects of black-white brightness contrast on the brain response were investigated...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29060092/analysis-of-computerized-optokinetic-nystagmus-induction-and-effect-of-contrast-on-ocular-fatigue
#17
Ji Sung Kim, Changhoon Baek, Sunyoung Yoo, Jeong-Min Hwang, Jong Mo Seo
Optokinetic nystagmus (OKN) is useful in evaluating visual function objectively, and the classical black-and-white-striped OKN drum is being replaced by video or computer monitor. However, the examinee may feel fatigue during test because of high contrast of luminous pattern from monitor. This paper suggests a plan to reduce eye fatigue of participant by decreasing contrast of patterns without reducing OKN response. Alternating black and white stripes are shown on flat-panel liquid-crystal display monitor and moved horizontally to evoke OKN of the examinee, and the OKN wasW observed through electrooculography (EOG)...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29057069/giving-eyespots-a-shiner-pharmacologic-manipulation-of-the-io-moth-wing-pattern
#18
Andrei Sourakov
Our knowledge of wing pattern formation in Lepidoptera has advanced significantly in recent years due to the careful examination of several groups of butterflies. The eyespot is a prominent feature of Lepidoptera wing pattern, especially in the family Saturniidae. The present study examined how sulfated polysaccharides, which are known to simulate cold shock effect in nymphalid butterflies, affected the wing pattern formation of the Io moth, Automeris io (Saturniidae).  Prepupae and pupae of this species were subjected to injections of heparin and cold shock...
2017: F1000Research
https://www.readbyqxmd.com/read/29047503/subpixel-area-based-evaluation-for-crosstalk-suppression-in-quasi-three-dimensional-displays
#19
Zhenfeng Zhuang, Phil Surman, Qijia Cheng, Simon Thibault, Yuanjin Zheng, Xiao Wei Sun
A subpixel area-based evaluation method for an improved slanted lenticular film that minimizes the crosstalk in a quasi-three-dimensional (Q3D) display is proposed in this paper. To identify an optimal slant angle of the film, a subpixel area-based measurement is derived to evaluate the crosstalk among viewing regions of the intended subpixel and adjacent unintended subpixel by taking the real subpixel shape and black matrix into consideration. The subpixel mapping, which corresponds to the optimal slant angle of the film, can then be determined...
July 1, 2017: Applied Optics
https://www.readbyqxmd.com/read/29036109/transparency-in-stereopsis-parallel-encoding-of-overlapping-depth-planes
#20
Adam Reeves, David Lynch
We report that after extensive training, expert adults can accurately report the number, up to six, of transparent overlapping depth planes portrayed by brief (400 ms or 200 ms) random-element stereoscopic displays, and can well discriminate six from seven planes. Naïve subjects did poorly above three planes. Displays contained seven rows of 12 randomly located ×'s or +'s; jittering the disparities and number in each row to remove spurious cues had little effect on accuracy. Removing the central 3° of the 10° display to eliminate foveal vision hardly reduced the number of reportable planes...
August 1, 2017: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
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