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https://www.readbyqxmd.com/read/28078660/racial-ethnic-disparities-in-diabetes-quality-of-care-the-role-of-healthcare-access-and-socioeconomic-status
#1
Juan R Canedo, Stephania T Miller, David Schlundt, Mary K Fadden, Maureen Sanderson
INTRODUCTION: Blacks, Hispanics, and Asians are disproportionately affected by diabetes. We assessed the state of racial/ethnic disparities in diabetes quality of care in the USA. METHODS: We analyzed cross-sectional data of adults diagnosed with Type 2 diabetes in the nationally representative 2013 Medical Expenditure Panel Survey. Differences in adherence to five diabetes quality of care recommendations (HbA1c twice yearly, yearly foot exam, dilated eye exam, blood cholesterol test, and flu vaccination) were examined by race/ethnicity while controlling for three social determinants of health (health insurance status, poverty, and education) and other demographic variables...
January 11, 2017: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/28053351/functional-analysis-of-the-abcs-of-eye-color-in-helicoverpa-armigera-with-crispr-cas9-induced-mutations
#2
Sher Afzal Khan, Michael Reichelt, David G Heckel
Many insect pigments are localized in subcellular pigment granules, and transport of pigment precursors from the cytoplasm is accomplished by ABC proteins. Drosophila melanogaster has three half-transporter genes (white, scarlet, and brown, all affecting eye pigments) and Bombyx mori has a fourth (ok). The White, Brown, Scarlet and Ok proteins each have one transmembrane and one cytoplasmic domain and they heterodimerize to form functional transporters with different substrate specificities. We used CRISPR/Cas9 to create somatic and germ-line knockout mutations of these four genes in the noctuid moth Helicoverpa armigera...
January 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28024137/-secrets-of-the-red-headed
#3
REVIEW
Zygmunt Zdrojewicz, Małgorzata Kowalik, Adam Jagodziński
Only 1-2% of people is red-headed but in the Russian Udmurt Republic or United Kingdom they can be met more often. A specific variant of MC1R gene (R allele) is responsible for the red hair. The gene encodes a receptor for melanocortins. These substances stimulate melanocytes to product melanin- a dye of the skin which is transported to keratinocytes. It protects a cellular nucleus from ultraviolet radiation. Melanin has two types: eumelanin which is dark brown or even black and red/orange pheomelanin. The second one is mostly observed in red-headed which is caused by R allele...
December 22, 2016: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28006799/-i-cobitis-i-i-nalbanti-i-a-new-species-of-spined-loach-from-south-korea-and-redescription-of-i-cobitis-lutheri-i-teleostei-cobitidae
#4
Ekaterina D Vasil'eva, Daemin Kim, Victor P Vasil'ev, Myeong-Hun Ko, Yong-Jin Won
Cobitis nalbanti, new species, is described from the South Korean Han and Geum Rivers, draining to the Yellow Sea. It differs from its congeners by having a wide, ovoid lamina circularis; rounded scales with a large, slightly-displaced focal zone; a relatively long, protruded snout; the suborbital spine not reaching the center of the eye; the mandibular barbel not reaching the anterior edge of the eye; usually 12-14 dark brown blotches in the fourth Gambetta's zone; a single elongated black spot on the upper part of the caudal-fin base; the only streak on the head running from the tip of the snout to the nape, across the eye; 2n=48-51 and NF=66...
December 21, 2016: Zootaxa
https://www.readbyqxmd.com/read/28004086/beyond-the-use-of-an-explanatory-key-accompanying-submicroscopic-representations
#5
Vesna Ferk Savec, Špela Hrast, Iztok Devetak, Gregor Torkar
When learning chemistry, students encounter various visualizations introducing scientific concepts and processes unobservable to the naked eye. It is often assumed that these visualizations support students' understanding and enable them to solve problems more efficiently. The research presented here investigates students' use of an explanatory key while solving tasks based on submicroscopic representations. The following features of the explanatory key were examined: 1) colored versus black-and-white, and 2) pictorial versus textual...
December 2016: Acta Chimica Slovenica
https://www.readbyqxmd.com/read/28003035/the-ontario-neurodegenerative-disease-research-initiative-ondri
#6
Sali M K Farhan, Robert Bartha, Sandra E Black, Dale Corbett, Elizabeth Finger, Morris Freedman, Barry Greenberg, David A Grimes, Robert A Hegele, Chris Hudson, Peter W Kleinstiver, Anthony E Lang, Mario Masellis, William E McIlroy, Paula M McLaughlin, Manuel Montero-Odasso, David G Munoz, Douglas P Munoz, Stephen Strother, Richard H Swartz, Sean Symons, Maria Carmela Tartaglia, Lorne Zinman, Michael J Strong
Because individuals develop dementia as a manifestation of neurodegenerative or neurovascular disorder, there is a need to develop reliable approaches to their identification. We are undertaking an observational study (Ontario Neurodegenerative Disease Research Initiative [ONDRI]) that includes genomics, neuroimaging, and assessments of cognition as well as language, speech, gait, retinal imaging, and eye tracking. Disorders studied include Alzheimer's disease, amyotrophic lateral sclerosis, frontotemporal dementia, Parkinson's disease, and vascular cognitive impairment...
December 22, 2016: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/27988596/-i-leptobotia-i-i-bellacauda-i-a-new-species-of-loach-from-the-lower-yangtze-basin-in-china-teleostei-cypriniformes-botiidae
#7
Jörg Bohlen, Vendula Šlechtová
A new species, Leptobotia bellacauda is described from the lower Yangtze River basin. The new species is distinguished from all other species of Leptobotia by a combination of the following characters: body plain brown, prominent black bar in caudal fin, dorsal half of head dusky black, ventral half of head cream colour, eye well developed, lobes of caudal fin rounded, origin of pelvic fins beneath or anterior to dorsal-fin origin, and pectoral fin in adult males enlarged, with numerous tubercles.
December 4, 2016: Zootaxa
https://www.readbyqxmd.com/read/27988552/two-new-species-of-the-genus-i-sphingonotus-i-fieber-1852-orthoptera-oedipodidae-from-china
#8
Cheng-Quan Cao, Jian-Ping Shi, Zhan Yin
Two new species of the genus Sphingonotus Fieber, 1852, namely Sphingonotus taiwanensis sp. nov. and Sphingonotus zhongningensis sp. nov. are described in this paper from China. The new species Sphingonotus taiwanensis sp. nov. is similar to Sphingonotus nebulosus (Fiescher-Waldheim, 1846), but differs from the latter by interspace of mesosternum wider, width 1.8 times the length; hind femur pale red on inner side; hind tibia pale red, with 13 spines on inner side and 10 spines on outer side; hind wing pale yellow at base...
December 12, 2016: Zootaxa
https://www.readbyqxmd.com/read/27968782/using-eye-tracking-technology-to-capture-the-visual-attention-of-nurses-during-interpretation-of-patient-monitoring-scenarios-from-a-computer-simulated-bedside-monitor
#9
Jonathan Currie, Raymond R Bond, Paul McCullagh, Pauline Black, Dewar D Finlay, Aaron Peace
No abstract text is available yet for this article.
November 2016: Journal of Electrocardiology
https://www.readbyqxmd.com/read/27927093/optomotor-reactions-reveal-polarization-sensitvity-in-the-zika-virus-transmitting-yellow-fever-mosquito-aedes-stegomyia-aegypti-diptera-nematocera
#10
Balazs Bernáth, Victor Benno Meyer-Rochow
In polarization-sensitive insect species an orthogonal arrangement of photoreceptive microvilli is a characteristic feature. However, mosquito eyes had not revealed this feature, and polarization sensitivity (PS) was considered to be non-existent in them. Recently, however, gravid Aedes (Stegomyia) aegypti females were found to possess PS, sequels of which could be demonstrated only in the absence of chemicals emitted by conspecifics. Therefore, PS in Ae. aegypti, unlike that of other aquatic insects, apparently does not play a dominant role in locating water bodies, and is difficult to demonstrate in situations free of chemical cues...
December 2016: Zoological Science
https://www.readbyqxmd.com/read/27919403/trace-amine-associated-receptor-1-agonists-as-narcolepsy-therapeutics
#11
Sarah W Black, Michael D Schwartz, Tsui-Ming Chen, Marius C Hoener, Thomas S Kilduff
BACKGROUND: Narcolepsy, a disorder of rapid eye movement (REM) sleep, is characterized by excessive daytime sleepiness and cataplexy, a loss of muscle tone triggered by emotional stimulation. Current narcolepsy pharmacotherapeutics include controlled substances with abuse potential or drugs with undesirable side effects. As partial agonists at trace amine-associated receptor 1 (TAAR1) promote wakefulness in mice and rats, we evaluated whether TAAR1 agonism had beneficial effects in two mouse models of narcolepsy...
October 18, 2016: Biological Psychiatry
https://www.readbyqxmd.com/read/27899373/influence-of-geolocation-and-ethnicity-on-the-phenotypic-expression-of-primary-sj%C3%A3-gren-s-syndrome-at-diagnosis-in-8310-patients-a-cross-sectional-study-from-the-big-data-sj%C3%A3-gren-project-consortium
#12
Pilar Brito-Zerón, Nihan Acar-Denizli, Margit Zeher, Astrid Rasmussen, Raphaele Seror, Elke Theander, Xiaomei Li, Chiara Baldini, Jacques-Eric Gottenberg, Debashish Danda, Luca Quartuccio, Roberta Priori, Gabriela Hernandez-Molina, Aike A Kruize, Valeria Valim, Marika Kvarnstrom, Damien Sene, Roberto Gerli, Sonja Praprotnik, David Isenberg, Roser Solans, Maureen Rischmueller, Seung-Ki Kwok, Gunnel Nordmark, Yasunori Suzuki, Roberto Giacomelli, Valerie Devauchelle-Pensec, Michele Bombardieri, Benedikt Hofauer, Hendrika Bootsma, Johan G Brun, Guadalupe Fraile, Steven E Carsons, Tamer A Gheita, Jacques Morel, Cristina Vollenveider, Fabiola Atzeni, Soledad Retamozo, Ildiko Fanny Horvath, Kathy Sivils, Thomas Mandl, Pulukool Sandhya, Salvatore De Vita, Jorge Sanchez-Guerrero, Eefje van der Heijden, Virginia Fernandes Moça Trevisani, Marie Wahren-Herlenius, Xavier Mariette, Manuel Ramos-Casals
OBJECTIVES: To analyse the influence of geolocation and ethnicity on the clinical presentation of primary Sjögren's syndrome (SjS) at diagnosis. METHODS: The Big Data Sjögren Project Consortium is an international, multicentre registry designed in 2014. By January 2016, 20 centres from five continents were participating. Multivariable logistic regression analyses were performed. RESULTS: We included 7748 women (93%) and 562 men (7%), with a mean age at diagnosis of primary SjS of 53 years...
November 29, 2016: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/27894007/infant-attention-to-same-and-other-race-faces
#13
Anantha Singarajah, Jill Chanley, Yoselin Gutierrez, Yoselin Cordon, Bryan Nguyen, Lauren Burakowski, Scott P Johnson
We recorded visual attention to same- and other-race faces in Hispanic and White 11-month-old infants, an age at which face processing is presumably biased by an own-race recognition advantage. Infants viewed pairs of faces differing in race or ethnicity as their eye movements were recorded. We discovered consistently greater attention to Black over Hispanic faces, to Black faces over White faces, and to Hispanic over White faces. Inversion of face stimuli, and infant ethnicity, had little effect on performance...
February 2017: Cognition
https://www.readbyqxmd.com/read/27890475/slowed-dark-adaptation-in-older-eyes-effect-of-location
#14
Humza J Tahir, Elena Rodrigo-Diaz, Neil R A Parry, Jeremiah M F Kelly, D Carden, Ian J Murray
PURPOSE: The rate of rod sensitivity recovery following a photobleach is a basic measure of the integrity of the outer retina. Rods are selectively impaired in aging and many disorders of the retina, notably Age-Related Macular Degeneration (AMD). It is not known for certain whether the age-related deficit is a pan-retinal effect or if there are localised regions of impaired rod function. To address this important issue a dual arc stimulus was developed that samples sensitivity recovery in two retinal locations...
November 24, 2016: Experimental Eye Research
https://www.readbyqxmd.com/read/27890189/diplopia-what-to-double-check-in-radiographic-imaging-of-double-vision
#15
REVIEW
Claudia F E Kirsch, Karen Black
When patients see double with both eyes open, known as "binocular diplopia," this may be a harbinger of underlying life-threatening causes. This article presents pertinent anatomy, critical abnormality, and radiographic features that should be double checked for in diplopia. Key areas requiring a double check using the acronym VISION include Vascular, Infectious and Inflammatory, the Scalp for giant cell arteritis, Sphenoid and Skull base in trauma, Increased intracranial pressure (pseudotumor cerebri), Onset of new headaches or psychosis, and Neoplasm...
January 2017: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/27870777/minocycline-induced-scleral-and-dermal-hyperpigmentation
#16
Cheryl Haskes, Michael Shea, David Imondi
PURPOSE: To present a case of minocycline-induced blue scleral pigmentation and discuss the pathophysiology and differential diagnoses. The uses, mechanisms, and other adverse effects of minocycline will also be highlighted. CASE REPORT: An elderly Caucasian male patient presented for routine ocular examination complaining of blue discoloration to the whites of his eyes. He was found to have bilateral blue scleral pigmentation and blue discoloration to various other dermal areas of his body...
November 18, 2016: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/27867747/early-diagnosis-of-genital-mucosal-melanoma-how-good-are-our-dermoscopic-criteria
#17
Tova Rogers, Melissa Pulitzer, Maria L Marino, Ashfaq A Marghoob, Oliver Zivanovic, Michael A Marchetti
BACKGROUND: There are limited studies on the dermoscopic features of mucosal melanoma, particularly early-stage lesions. Described criteria include the presence of blue, gray, or white colors, with a reported sensitivity of 100%. It is unclear if these features will aid in the detection of early mucosal melanoma or improve diagnostic accuracy compared to naked-eye examination alone. CASE: An Asian female in her fifties was referred for evaluation of an asymptomatic, irregularly pigmented patch of the clitoral hood and labia minora of unknown duration...
October 2016: Dermatology Practical & Conceptual
https://www.readbyqxmd.com/read/27863843/score2-report-2-study-design-and-baseline-characteristics
#18
Ingrid U Scott, Paul C VanVeldhuisen, Michael S Ip, Barbara A Blodi, Neal L Oden, Maria Figueroa, Pravin U Dugel
PURPOSE: To describe the design and baseline characteristics of participants in the Study of COmparative Treatments for REtinal Vein Occlusion 2 (SCORE2) and to compare with cohorts from other retinal vein occlusion trials. DESIGN: Phase III prospective, multicenter, randomized clinical trial designed to assess whether intravitreal bevacizumab is noninferior to intravitreal aflibercept for treatment of decreased vision attributable to macular edema associated with central retinal vein occlusion (CRVO) or hemiretinal vein occlusion (HRVO)...
November 15, 2016: Ophthalmology
https://www.readbyqxmd.com/read/27859996/microphthalmia-associated-transcription-factor-ensures-the-elongation-of-axons-and-dendrites-in-the-mouse-frontal-cortex
#19
Koji Ohba, Kazuhisa Takeda, Tamio Furuse, Tomohiro Suzuki, Shigeharu Wakana, Takashi Suzuki, Hiroaki Yamamoto, Shigeki Shibahara
Long interspersed element-1 (LINE-1) is a mammalian transposable element, and its genomic insertion could cause neurological disorders in humans. Incidentally, LINE-1 is present in intron 3 of the microphthalmia-associated transcription factor (Mitf) gene of the black-eyed white mouse (Mitf(mi-bw) allele). Mice homozygous for the Mitf(mi-bw) allele show the white coat color with black eye and deafness. Here, we explored the functional consequences of the LINE-1 insertion in the Mitf gene using homozygous Mitf(mi-bw) mice on the C3H background (C3H-bw mice) or on the C57BL/6 background (bw mice)...
December 2016: Genes to Cells: Devoted to Molecular & Cellular Mechanisms
https://www.readbyqxmd.com/read/27858151/chimney-sweeps-in-sweden-a-questionnaire-based-assessment-of-long-term-changes-in-work-conditions-and-current-eye-and-airway-symptoms
#20
Ayman Alhamdow, Per Gustavsson, Lars Rylander, Kristina Jakobsson, Håkan Tinnerberg, Karin Broberg
OBJECTIVES: To explore chimney sweeping work tasks, chimney sweeps' use of protective equipment, and type of fuel used by clients, over time. Further, to assess work-relatedness of current eye and airway symptoms. METHODS: In a cross-sectional study in 2011, male Swedish chimney sweeps (n = 483; age 21-69 years) answered a questionnaire about their occupational history and eye and airway symptoms. RESULTS: Between 1960 and 2010, black-soot-sweeping in private homes was the major task, although it decreased during the time period, for chimney sweeps...
November 17, 2016: International Archives of Occupational and Environmental Health
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