keyword
MENU ▼
Read by QxMD icon Read
search

Intraoperative Radiotherapy

keyword
https://www.readbyqxmd.com/read/29791029/development-of-a-3d-ultrasound-guidance-system-for-permanent-breast-seed-implantation
#1
Justin Michael, Daniel Morton, Deidre Batchelar, Michelle Hilts, Juanita Crook, Aaron Fenster
PURPOSE: Permanent breast seed implantation (PBSI) is a promising radiotherapy technique for early-stage breast cancer, completed in a single visit by permanently implanting 103 Pd seeds using needles inserted through a template and guided by 2D ultrasound (US). However, operator dependence has been highlighted as a limitation of this procedure. Consequently, we propose and have developed an intraoperative guidance system using 3D US and an instrumented mechanical arm to provide intraoperative 3D imaging and needle template tracking...
May 23, 2018: Medical Physics
https://www.readbyqxmd.com/read/29783001/laparoscopic-extraperitoneal-pelvic-lymph-node-debulking-in-locally-advanced-cervical-cancer
#2
Diaz-Feijoo Berta, Luna-Guibourg Rocio, Cabrera Silvia, Manrique Susana, Gil-Moreno Antonio
OBJECTIVE: To demonstrate the feasibility of laparoscopic extraperitoneal approach for pelvic metastatic lymph node debulking in locally advanced cervical cancer. DESIGN: Surgical video article. Canadian task force Classification III. SETTING: University Hospital PATIENT: A 52 year-old patient presented a stage IIA2 Cervical adenocarcinoma according to FIGO classification. The physical exam reported a 45 mm tumor. Positron emission tomography (PET- CT) was positive for hypermetabolic enlarged lymph nodes in left external iliac region of 1...
May 18, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29781071/wound-fluids-collected-from-patients-after-iort-treatment-activates-extrinsic-apoptotic-pathway-in-mcf7-breast-cancer-cell-line
#3
Katarzyna Ida Kulcenty, Igor Piotrowski, Karolina Zaleska, Dawid Murawa, Wiktoria Maria Suchorska
OBJECTIVES: Intraoperative radiotherapy (IORT) relates to irradiation of diseased tissue during the surgery within the tumor bed. The reason for this process is based on the fact that the increase in the radiation dose increases local tumor control. It was shown that postoperative fluids obtained from patients after breast cancer conserving surgery, stimulated motility and invasiveness of tumor cells in vitro. The results obtained from TARGIT clinical trial demonstrated that IORT significantly inhibits the stimulatory effect of wound fluids on tumor cells in vitro...
2018: Ginekologia Polska
https://www.readbyqxmd.com/read/29773240/perioperative-risk-factors-that-predict-complications-of-radial-forearm-free-flaps-in-oral-and-maxillofacial-reconstruction
#4
C Wang, G Fu, F Liu, L Liu, M Cao
The aim of the study was to find out what perioperative risk factors predicted complications in patients having reconstructions with radial forearm free flaps (RFFF). We organised a retrospective study of 169 patients (mean (range) age 54 (22-86) years, 100 of whom were female) who had oral and maxillofacial tumours resected, and reconstructed with RFFF, from January 2011-December 2016. We recorded predictive variables, subdivided into: personal and clinical (sex, age, weight, coexisting conditions, history of smoking, radiotherapy, and primary lesions); haemodynamic (perioperative concentrations of haemoglobin and albumin, blood loss, blood transfusion, urinary output (ml), and rate (ml/kg/hour), and infusion rates for crystalloids and colloids (ml/kg/hour, and volumes given intraoperatively and postoperatively for 24hours); and anaesthetic and surgical (American Society of Anesthesiologists(ASA) grade, visual analogue pain score (VAS), and duration of tourniquet and operation)...
May 14, 2018: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/29762444/efficacy-of-autologous-platelet-concentrates-as-adjuvant-therapy-to-surgical-excision-in-the-treatment-of-keloid-scars-refractory-to-conventional-treatments-a-pilot-prospective-study
#5
Barbara Hersant, Mounia SidAhmed-Mezi, Frédéric Picard, Oana Hermeziu, Anne-Marie Rodriguez, Khaled Ezzedine, Jean Paul Meningaud
BACKGROUND: After conventional treatments, keloid scars show varying degrees of recurrence. The aim of this study was to assess the efficacy and safety of platelet-rich plasma in the treatment of postoperative keloid scars refractory to conventional treatments. METHODS: This pilot prospective study was conducted in 17 patients with keloid scars who did not respond to 4 injections of cortisone or radiotherapy after extralesional resection of keloid. Platelet-rich plasma was injected intraoperatively and then 3 times with a 1-month interval...
May 14, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29751323/evaluation-of-dosimetric-properties-of-shielding-disk-used-in-intraoperative-electron-radiotherapy-a-monte-carlo-study
#6
Mostafa Robatjazi, Hamid Reza Baghani, Seied Rabi Mahdavic, Giuseppe Felici
A shielding disk is used for IOERT procedures to absorb radiation behind the target and protect underlying healthy tissues. Setup variation of shielding disk can affect the corresponding in-vivo dose distribution. In this study, the changes of dosimetric parameters due to the disk setup variations is evaluated using EGSnrc Monte Carlo (MC) code. The results can help treatment team to decide about the level of accuracy in the setup procedure and delivered dose to the target volume during IOERT.
May 1, 2018: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/29741977/laparoscopic-pelvic-exenteration-for-locally-advanced-rectal-cancer-technique-and-short-term-outcomes
#7
Ashish Pokharkar, Praveen Kammar, Ashwin D'souza, Rahul Bhamre, Pavan Sugoor, Avanish Saklani
BACKGROUND: Since last two decades minimally invasive techniques have revolutionized surgical field. In 2003 Pomel first described laparoscopic pelvic exenteration, since then very few reports have described minimally invasive approaches for total pelvic exenteration. METHODS: We report the 10 cases of locally advanced rectal adenocarcinoma which were operated between the periods from March 1, 2017 to November 11, 2017 at the Tata Memorial Hospital, Mumbai. All male patients had lower rectal cancer with prostate involvement on magnetic resonance imaging (MRI)...
May 9, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29738162/-radical-retropubic-prostatectomy-for-prostate-cancer-with-pelvic-lymph-node-metastasis
#8
Ding-Yi Liu, Sang Hu, Yan-Feng Zhou, Hong-Chao He, Jia-Shun Yu, Jian Wang, Wei-Mu Xia, Qi Tang, Ming-Wei Wang, Wen-Long Zhou
Objective: To investigate the safety and effectiveness of radical retropubic prostatectomy (RRP) with adjuvant androgen deprivation or external radiotherapy in the treatment of prostate cancer (PCa) with pelvic lymph node metastasis (PLNM). METHODS: Twenty PCa patients underwent bilateral pedal lymphangiography (PLG) preoperatively, and 11 of them received lymph node aspiration for examination of the mRNA expressions of prostate-specific antigen (PSA) and prostate-specific membrane antigen (PSMA) in the lymph fluid by real-time RT-PCR...
November 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/29732339/monte-carlo-simulation-of-electron-beams-produced-by-liac-intraoperative-radiation-therapy-accelerator
#9
M Robatjazi, S R Mahdavi, H R Baghani, H R Mirzaei, M Mousavi, N Nafissi, E Akbari
Background: One of the main problems of dedicated IORT accelerators is to determine dosimetric characteristics of the electron beams. Monte Carlo simulation of IORT accelerator head and produced beam will be useful to improve the accuracy of beam dosimetry. Materials and Methods: Liac accelerator head was modeled using the BEAMnrcMonte Carlo simulation system. Phase-space files were generated at the bottom of the applicators. These phase-space files were used as an input source in DOSXYZnrc and BEAMDP codes for dose calculation and analysis of the characteristic of the electron beams in all applicators and energies...
March 2018: Journal of Biomedical Physics & Engineering
https://www.readbyqxmd.com/read/29731428/three-piece-inflatable-penile-prosthesis-placement-following-pelvic-radiation-technical-considerations-and-contemporary-outcomes
#10
Jeffrey Loh-Doyle, Mukul B Patil, Zein Nakhoda, Nima Nassiri, Wesley Yip, Kevin Wayne, Leo Doumanian, Stuart D Boyd
BACKGROUND: Pelvic radiation is a known risk factor for the development and progression of erectile dysfunction. When medical therapy fails, the 3-piece inflatable penile prosthesis (IPP) can offer patients a definitive treatment option. Because of radiation-induced vascular changes and tissue fibrosis, a careful surgical approach is necessary to avoid intraoperative complications and attain successful outcomes. Despite its widespread use in prostate cancer treatment, there are no contemporary studies examining the effects that pelvic radiation can have on 3-piece IPP placement and device survival...
May 3, 2018: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29707108/glioblastoma-specific-anti-tufm-nanobody-for-in-vitro-immunoimaging-and-cancer-stem-cell-targeting
#11
Neja Samec, Ivana Jovcevska, Jure Stojan, Alja Zottel, Mirjana Liovic, Michael P Myers, Serge Muyldermans, Jernej Šribar, Igor Križaj, Radovan Komel
Glioblastoma multiforme (GBM) is the most common and lethal form of brain tumor. The prognosis for patients remains poor, despite the combination of new preoperative and intraoperative neuroimaging, radical surgery, and recent advances in radiotherapy and chemotherapy. To improve GBM therapy and patient outcome, sustained drug delivery to glioma cells is needed, while minimizing toxicity to adjacent neurons and glia cells. This might be achieved through an anti-proteomic approach based on nanobodies, the single-domain antigen-binding fragments of heavy-chain antibodies of the camelid adaptive immune system...
April 3, 2018: Oncotarget
https://www.readbyqxmd.com/read/29688510/study-protocol-early-stereotactic-gamma-knife-radiosurgery-to-residual-tumor-after-surgery-of-newly-diagnosed-glioblastoma-gamma-gbm
#12
Stefanie Brehmer, Mario Alexander Grimm, Alex Förster, Marcel Seiz-Rosenhagen, Grit Welzel, Florian Stieler, Frederik Wenz, Christoph Groden, Sabine Mai, Daniel Hänggi, Frank Anton Giordano
BACKGROUND: Glioblastoma (GBM) is the most common malignant brain tumor in adult patients. Tumor recurrence commonly occurs around the resection cavity, especially after subtotal resection (STR). Consequently, the extent of resection correlates with overall survival (OS), suggesting that depletion of postoperative tumor remnants will improve outcome. OBJECTIVE: To assess safety and efficacy of adding stereotactic radiosurgery (SRS) to the standard treatment of GBM in patients with postoperative residual tumor...
April 24, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29682708/-early-diagnosis-and-treatment-of-anastomotic-leak-after-rectal-cancer-surgery
#13
Tinghan Yang, Ziqiang Wang
Anastomotic leakage is the most common major complication after mid-low rectal cancer surgery. Due to lack of knowledge regarding the virtual mechanisms of anastomotic leakage, not much can be done to prevent its development. The aim of the present review was to discuss the prevention, early diagnosis, and treatment of anastomotic leakage after rectal cancer surgery. For patients with risk factors, such as anastomotic site within 4 cm from anus, obese men, lack of blood supply of the anastomotic site, neoadjuvant chemo radiotherapy, or patients with severe co-morbidity, aggressive preventive strategy should be adopted...
2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29680448/the-role-of-intraoperative-radiotherapy-iort-in-the-management-of-patients-with-pancreatic-and-periampullary-cancer-a-single-center-experience
#14
Ayman Zaki Azzam, Ahmed Alqarni, Tarek Mahmoud Amin
BACKGROUND: In spite of the advances in modern surgery, the outcome for patients suffering from pancreatic adenocarcinoma or periampullary adenocarcinoma is still bad. Recently, introperative radiotherapy (IORT) was introduced into the multimodality management approach to improve both tumor control and patient' survival. AIM OF WORK: To evaluate our initial experience in combined surgical resection and IORT, and to evaluate the feasibility of the application of IORT and its effect on morbidity, mortality and local recurrence...
April 18, 2018: Journal of the Egyptian National Cancer Institute
https://www.readbyqxmd.com/read/29674010/one-step-intraoperative-radiotherapy-optimizes-conservative-treatment-of-breast-cancer-with-advantages-in-quality-of-life-and-work-resumption
#15
Luca Sorrentino, Susanna Fissi, Ilaria Meaglia, Daniela Bossi, Ottavia Caserini, Serena Mazzucchelli, Marta Truffi, Sara Albasini, Paola Tabarelli, Marco Liotta, Giovanni B Ivaldi, Fabio Corsi
BACKGROUND: Intraoperative radiotherapy (IORT) could be not-inferior to external beam radiotherapy (EBRT) in selected patients, but toxicities, self-perception of body image, quality of life, and resumption of work or daily activities have been poorly explored. The aim of the present study was to compare these outcomes between EBRT, IORT full-dose (IORT-f) and IORT boost (IORT-b). METHODS: 443 consecutive patients, candidates for breast-conserving surgery, were included: EBRT was performed in 220 patients (49...
April 16, 2018: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29668359/laparoscopic-total-mesorectal-excision-following-transanal-endoscopic-microsurgery-for-rectal-cancer
#16
Nidal Issa, Yaniv Fenig, Rachel Gingold-Belfer, Muhammad Khatib, Wisam Khoury, Lea Wolfson, Hemda Schmilovitz-Weiss
BACKGROUND: Patients' selection for transanal endoscopic microsurgery (TEM) depends on diagnostic modalities; however, there are still some limitations in the preoperative diagnosis of rectal lesions, and in some reports, up to third of the adenomas resected by TEM were found to be adenocarcinoma; therefore, salvage radical resection (RR) remains necessary for achieving oncological resection. Salvage RR may encounter some technical problems as the violation of the mesorectum and the scar formation...
April 18, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29660396/analysis-of-clinical-management-of-infected-breast-implants-and-of-factors-associated-to-successful-breast-pocket-salvage-in-infections-occurring-after-breast-reconstruction
#17
Simonetta Franchelli, Marianna Pesce, Ilaria Baldelli, Anna Marchese, Pierluigi Santi, Andrea De Maria
OBJECTIVES: Considerable efforts have been devoted so far to improve salvage procedures of infected breast implants in absence of defined guidelines or validated clinical protocols. Within a cohort of prospectively recruited patients who underwent breast reconstruction, we performed a retrospective review of proven implant infections in order to describe factors contributing to management success. METHODS: We collected data in 1293 consecutive patients who underwent two stage (expander+ prosthesis) breast reconstruction with at least 12 months of follow-up...
April 13, 2018: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29618055/malignancy-index-using-intraoperative-flow-cytometry-is-a-valuable-prognostic-factor-for-glioblastoma-treated-with-radiotherapy-and-concomitant-temozolomide
#18
Taiichi Saito, Yoshihiro Muragaki, Takahiro Shioyama, Takashi Komori, Takashi Maruyama, Masayuki Nitta, Takayuki Yasuda, Junji Hosono, Saori Okamoto, Takakazu Kawamata
BACKGROUND: Intraoperative prediction of radiochemosensitivity is desirable for improving the clinical management of glioblastoma (GBM) patients. We have previously developed an original technique for intraoperative flow cytometry (iFC) and defined a malignancy index (MI). OBJECTIVE: To determine whether MI correlates with prognosis in GBM patients who underwent the standard treatment protocol of radiotherapy and temozolomide administration. METHODS: The current study included 102 patients with GBM that had been newly diagnosed from 2010 to 2015 who underwent our iFC analysis and received the standard treatment protocol...
March 30, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29615840/biomarker-expression-in-rectal-cancer-tissue-before-and-after-neoadjuvant-therapy
#19
Leonora Sf Boogerd, Maxime Jm van der Valk, Martin C Boonstra, Hendrica Ajm Prevoo, Denise E Hilling, Cornelis Jh van de Velde, Cornelis Fm Sier, Arantza Fariña Sarasqueta, Alexander L Vahrmeijer
Purpose: Intraoperative identification of rectal cancer (RC) can be challenging, especially because of fibrosis after treatment with preoperative chemo- and radiotherapy (CRT). Tumor-targeted fluorescence imaging can enhance the contrast between tumor and normal tissue during surgery. Promising targets for RC imaging are carcinoembryonic antigen (CEA), epithelial cell adhesion molecule (EpCAM) and the tyrosine-kinase receptor Met (c-Met). The effect of CRT on their expression determines their applicability for imaging...
2018: OncoTargets and Therapy
https://www.readbyqxmd.com/read/29588242/primary-spinal-malignant-mesothelioma-a-case-report-and-literature-review
#20
Fan Chen, Beifang Liu, Ying Yu, Jianyang Du, Dawei Chen
BACKGROUND: Malignant mesotheliomas are aggressive and rapidly-fatal neoplasms arising from the mesothelial cells. The most common sites of origin are the pleural and peritoneal cavities, and additionally, malignant mesotheliomas can also infrequently involve the pericardium and the tunica vaginalis. However, malignant mesothelioma occurring in the spinal canal is extremely rare. Herein, we reported a case with primary spinal malignant mesothelioma. METHODS: A literature search was using PubMed with specific key terms, inclusion criteria, and exclusion criteria...
March 24, 2018: World Neurosurgery
keyword
keyword
22174
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"