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https://www.readbyqxmd.com/read/29785924/preliminary-evidence-for-the-absence-of-cystic-echinococcosis-in-gabon-a-cross-sectional-pilot-survey-in-humans-and-definitive-hosts
#1
Felix Lötsch, Ghyslain Mombo-Ngoma, Johannes Mischlinger, Mirjam Groger, Luzia Veletzky, Ayôla Akim Adegnika, Bertrand Lell, Selidji Todagbe Agnandji, Marielle Bouyou-Akotet, Markus Obermüller, Marion Wassermann, Renate Schneider, Herbert Auer, Michael Ramharter
Cystic echinococcosis (CE) is a globally endemic zoonosis caused by the larval stage of the Echinococcus granulosus sensu lato (s.l.) complex. Although the disease is known to be highly prevalent in certain parts of North and East Africa, data on CE, both in humans and definitive hosts, are extremely scarce for Central Africa. The present study assessed the epidemiology of CE in humans and dogs in rural Gabon. An ultrasound and serologic survey was conducted in volunteers from rural villages in Gabon. A two-step approach was used for serological testing with an indirect hemagglutination assay as a screening test and Western Blot as a confirmatory test...
May 21, 2018: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29785806/chemiluminescence-of-copper-nanoclusters-and-its-application-for-trihexyphenidyl-hydrochloride-detection
#2
Xiaoxia Chen, Junmei Zhang, Yue Li, Suqin Han
Chemiluminescence (CL) of copper nanoclusters (CuNCs) induced by cerium (IV) (Ce(IV)) or potassium permanganate (KMnO4 ) in acidic medium was observed. The potential application of CuNCs CL in analytical chemistry was also demonstrated using trihexyphenidyl hydrochloride (THP) as an example based on its enhancing CL intensity for the CuNCs-Ce(IV)/KMnO4 systems. The excited state of the CuNCs acted as a luminophore in the CuNCs-Ce(IV) system, while CuNCs played the role of reductant in the CuNCs-KMnO4 system...
May 21, 2018: Luminescence: the Journal of Biological and Chemical Luminescence
https://www.readbyqxmd.com/read/29784425/a-novel-bioassay-based-on-aptamer-functionalized-magnetic-nanoparticle-for-the-detection-of-zearalenone-using-time-resolved-fluorescence-nayf-4-ce-tb-nanoparticles-as-signal-probe
#3
Sobia Niazi, Xiaole Wang, Imran Pasha, Imran Mahmood Khan, Sen Zhao, Muhammad Shoaib, Shijia Wu, Zhouping Wang
Zearalenone (ZEN) is a non-steroidal estrogenic mycotoxin produced by fungi on stored grains. The earlier detection methods used for ZEN rely on expensive equipment, time-consuming sample preparation and temperature sensitive antibodies. The current work, proposed a novel strategy based on ZEN aptamer labeled with amine-functionalized magnetic nanoparticle (MNPs) as a capture probe and time-resolved fluorescence (TRFL) nanoparticles labeled with complementary DNA (cDNA) as a signal probe. Under the optimized conditions, TRFL intensity at 544 nm was used to measure ZEN (R2 = 0...
August 15, 2018: Talanta
https://www.readbyqxmd.com/read/29784342/rapid-and-sensitive-detection-of-staphylococcus-aureus-assisted-by-polydopamine-modified-magnetic-nanoparticles
#4
Xiaomei Gao, Xin Yao, Zitao Zhong, Li Jia
Pathogens cause significant morbidity and mortality to humans. Thus, development of fast and reliable methods for detection and identification of pathogens is urgently needed to increase protection level of public health and ensure the safety of consumers. Herein, a rapid and sensitive method has been developed for Staphylococcus aureus (S. aureus) detection based on the dual role of polydopamine modified magnetic nanoparticles (PDA@Fe3 O4 NPs) combined with polymerase chain reaction (PCR) and capillary electrophoresis (CE)...
August 15, 2018: Talanta
https://www.readbyqxmd.com/read/29783114/geosphere-biosphere-circulation-of-chemical-elements-in-soil-and-plant-systems-from-a-100-km-transect-from-southern-central-norway
#5
Clemens Reimann, Karl Fabian, Belinda Flem, Malin Andersson, Peter Filzmoser, Peter Englmaier
Geochemical element separation is studied in 14 different sample media collected at 41 sites along an approximately 100-km long transect north of Oslo. At each site, soil C and O horizons and 12 plant materials (birch/spruce/cowberry/blueberry leaves/needles and twigs, horsetail, braken fern, pine bark and terrestrial moss) were sampled. The observed concentrations of 29 elements (K, Ca, P, Mg, Mn, S, Fe, Zn, Na, B, Cu, Mo, Co, Al, Ba, Rb, Sr, Ti, Ni, Pb, Cs, Cd, Ce, Sn, La, Tl, Y, Hg, Ag) were used to investigate soil-plant relations, and to evaluate the element differentiation between different plants, or between foliage and twigs of the same plant...
May 17, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29782632/prevalence-of-clinically-validated-primary-causes-of-end-stage-renal-disease-esrd-in-a-state-capital-in-northeastern-brazil
#6
Luana Rodrigues Sarmento, Paula Frassinetti Castelo Branco Camurça Fernandes, Marcelo Ximenes Pontes, Daniel Barros Santos Correia, Victhor Castelo Branco Chaves, Cecília Ferreira de Araújo Carvalho, Tiago Lima Arnaud, Matheus Henrique Seixas Dos Santos, Livia Cristina Barros Barreto, Larissa Alves Alexandre Moliterno
INTRODUCTION: Knowledge of validated primary causes of end-stage renal disease (ESRD) is extremely relevant in the realm of public health. The literature lacks validated studies on the primary causes of ESRD. OBJECTIVE: The aim of this study was to estimate the prevalence of the causes of ESRD in a State Capital in Northeastern Brazil. METHODS: This cross-sectional study was based on the analysis of medical records of patients on hemodialysis at five specialized centers in Fortaleza, CE, Brazil...
May 17, 2018: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
https://www.readbyqxmd.com/read/29781625/vertically-emitting-indium-phosphide-nanowire-lasers
#7
Wei-Zong Xu, Fang-Fang Ren, Dimitars Jevtics, Antonio Hurtado, Li Li, Qian Gao, Jiandong Ye, Fan Wang, Benoit Guilhabert, Lan Fu, Hai Lu, Rong Zhang, Hark Hoe Tan, Martin Dawson, Chennupati Jagadish
Semiconductor nanowire (NW) lasers have attracted considerable research effort given their excellent promise for nanoscale photonic sources. However, NW lasers currently exhibit poor directionality and high threshold gain, issues critically limiting their prospects for on-chip light sources with extremely reduced footprint and efficient power consumption. Here, we propose a new design and experimentally demonstrate a vertically emitting indium phosphide (InP) NW laser structure showing high emission directionality and reduced energy requirements for operation...
May 21, 2018: Nano Letters
https://www.readbyqxmd.com/read/29781206/electromembrane-extraction-and-capillary-electrophoresis-with-capacitively-coupled-contactless-conductivity-detection-multi-extraction-capabilities-to-analyse-trace-metals-from-saline-samples
#8
Macarena Silva, Carolina Mendiguchía, Carlos Moreno, Pavel Kubáň
Simultaneous electromembrane extraction (EME) of six trace metal cations (Cu2+ , Zn2+ , Co2+ , Ni2+ , Pb2+ , Cd2+ ) from saline samples was investigated. Capillary electrophoresis (CE) with capacitively coupled contactless conductivity detection (C4 D) was used to determine the metals in acceptor solutions due to its excellent compatibility with the minute volumes of acceptor solutions. Bis(2-ethylhexyl)phosphate (DEHPA) was selected as a suitable non-selective modifier for EME transport of target metal cations...
May 21, 2018: Electrophoresis
https://www.readbyqxmd.com/read/29780996/correction-insights-into-the-enhanced-ce-triple-bond-length-as-m-dash-n-triple-bond-in-the-hce-triple-bond-length-as-m-dash-n-molecule
#9
Zhen Pu, Wenjie Yu, Soumendra K Roy, Chaoyang Li, Bingyun Ao, Tianwei Liu, Maobing Shuai, Xuefeng Wang
Correction for 'Insights into the enhanced Ce[triple bond, length as m-dash]N triple bond in the HCe[triple bond, length as m-dash]N molecule' by Zhen Pu et al., Phys. Chem. Chem. Phys., 2017, 19, 8216-8222.
May 21, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29780472/on-the-role-of-ce-in-co-2-adsorption-and-activation-over-lanthanum-species
#10
Xinyu Li, Zhi-Jian Zhao, Liang Zeng, Jiubing Zhao, Hao Tian, Sai Chen, Kang Li, Sier Sang, Jinlong Gong
La2 O3 exhibits good performance for various catalytic applications, such as oxidative coupling of methane (OCM) and dry reforming of methane (DRM), during which coke formation may lead to the deactivation of catalysts. Typically, the reaction between CO2 adsorbed on La2 O3 and coke is the rate-determining step of the coke elimination process. This paper describes the influence of Ce addition on the CO2 adsorption and activation over La2 O3 . Combined with in situ and ex situ characterization and density functional theory (DFT) calculation, we show that Ce addition promotes the formation of bidentate carbonate on La2 O3 via tuning CO2 adsorption energy...
April 14, 2018: Chemical Science
https://www.readbyqxmd.com/read/29780469/tailored-metastable-ce-zr-oxides-with-highly-distorted-lattice-oxygen-for-accelerating-redox-cycles
#11
Zhe Zhang, Jiafeng Yu, Jixin Zhang, Qingjie Ge, Hengyong Xu, Felix Dallmann, Roland Dittmeyer, Jian Sun
Ceria-based catalysts are widely used in oxidation or oxidation-reduction reactions in the field of environmental science. Their catalytic functions are determined by their ability to exchange oxygen species with oxidants. The enhancement of oxygen release is desired since it is often the rate-determining step in redox cycles. Herein, we developed a lattice oxygen distortion method to enhance oxygen activation by quenching the Ce-Zr oxide nanoparticles formed from an extremely high temperature. This process can ensure the formation of solid solutions as well as avoiding atomic rearrangement during calcination, retaining the lattice oxygen at a metastable and disordered state without vacancies...
April 7, 2018: Chemical Science
https://www.readbyqxmd.com/read/29780006/investigation-of-the-applicability-of-a-rapid-diagnosis-test-in-the-diagnosis-of-cystic-echinococcosis
#12
Sema Ertuğ, Serçin Özlem Çalışkan, Erdoğan Malatyalı, Hatice Ertabaklar
OBJECTIVE: Echinococcus granulosus, the etiological agent of cystic echinococcosis (CE) in humans and livestock, is a widely distributed zoonotic pathogen tapeworm. The infection is transmitted to humans by the ingestion of E. granulosus eggs released in the feces of definitive hosts such as dogs. The larval stage of the parasite develops a slowly enlarging cyst in the visceral organs, particularly in the liver and/or lung. The aim of the present study was to evaluate the diagnostic value of an immunochromatographic test (ICT) for CE...
May 21, 2018: Türkiye Parazitolojii Dergisi
https://www.readbyqxmd.com/read/29779758/assessing-venous-thrombus-in-renal-cell-carcinoma-preliminary-results-for-unenhanced-3d-ssfp-mri
#13
L C Adams, B Ralla, G Engel, G Diederichs, B Hamm, J Busch, F Fuller, M R Makowski
AIM: To test the potential of unenhanced cardiac- and respiratory-motion-corrected three-dimensional steady-state free precession (3D-SSFP) magnetic resonance imaging (MRI) for the assessment of inferior vena cava (IVC) thrombus in patients with clear-cell renal cell carcinoma (cRCC), compared to standard contrast-enhanced (CE)-MRI and CE-computed tomography (CT). MATERIALS AND METHODS: Eighteen patients with cRCC and IVC thrombus, who received CE-MRI and 3D-SSFP at 1...
May 17, 2018: Clinical Radiology
https://www.readbyqxmd.com/read/29778448/multi-charged-labeling-of-oligosaccharides-and-n-linked-glycans-by-hexahistidine-based-tags-for-capillary-electrophoresis-mass-spectrometry-analysis
#14
Jan Partyka, Jana Krenkova, Richard Cmelik, Frantisek Foret
The labeling by amino acids and peptides was investigated for sensitive and fast analyses of oligosaccharides and N-linked glycans by capillary electrophoresis-mass spectrometry (CE-MS). Peptide tags with a various number of histidine residues were tested for maltooligosaccharide labeling in order to investigate the effect of the size of labels and a number of charges on CE-MS analysis. Nevertheless, the reductive amination labeling of N-linked glycans by a hexahistidine tag resulted in a multiple products formation, therefore a peptide tag was modified by hydrazine functionality in order to perform labeling by hydrazone formation chemistry...
May 16, 2018: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29778411/a-probable-primary-malignant-bone-tumor-in-a-pre-columbian-human-humerus-from-cerro-brujo-bocas-del-toro-panam%C3%A3
#15
Nicole E Smith-Guzmán, Jeffrey A Toretsky, Jason Tsai, Richard G Cooke
We present a rare case of primary bone cancer principally affecting the right humerus of a skeleton from the pre-Columbian site of Cerro Brujo (1265-1380 CE) in Bocas del Toro, on the Caribbean coast of Panamá, excavated in the early 1970s. The humerus contains a dense, calcified sclerotic mass with associated lytic lesions localized around the midshaft of the diaphysis. Evidence of systemic inflammation and anemia, likely caused by the cancer, are visible in the form of severe porotic hyperostosis of the cranial vault and bilateral periosteal reactions in the tibiae...
May 26, 2017: International Journal of Paleopathology
https://www.readbyqxmd.com/read/29778382/comparison-of-the-prevalence-of-chronic-endometritis-as-determined-by-means-of-different-diagnostic-methods-in-women-with-and-without-reproductive-failure
#16
Yingyu Liu, Xiaoyan Chen, Jin Huang, Chi-Chiu Wang, Mei-Yung Yu, Susan Laird, Tin-Chiu Li
OBJECTIVE: To compare the prevalence of chronic endometritis (CE) when different diagnostic methods are used. DESIGN: Prospective observational study. SETTING: University-affiliated hospital. PATIENT(S): Four groups of women were studied, including women with proven fertility (Fertile; n = 40), unexplained recurrent miscarriage (RM; n = 93), recurrent implantation failure (RIF; n = 39), and infertile subjects undergoing endometrial scratch in a natural cycle preceding frozen-thawed embryo transfer (Infertility; n = 48)...
May 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/29778166/morphological-and-molecular-diversity-of-arbuscular-mycorrhizal-fungi-in-revegetated-iron-mining-site-has-the-same-magnitude-of-adjacent-pristine-ecosystems
#17
Caroline Krug Vieira, Matheus Nicoletti Marascalchi, Arthur Vinicius Rodrigues, Rafael Dutra de Armas, Sidney Luiz Stürmer
Arbuscular mycorrhizal fungi (AMF) are important during revegetation of mining sites, but few studies compared AMF community in revegetated sites with pristine adjacent ecosystems. The aim of this study was to assess AMF species richness in a revegetated iron-mining site and adjacent ecosystems and to relate AMF occurrence to soil chemical parameters. Soil samples were collected in dry and rainy seasons in a revegetated iron-mining site (RA) and compared with pristine ecosystems of forest (FL), canga (NG), and Cerrado (CE)...
May 2018: Journal of Environmental Sciences (China)
https://www.readbyqxmd.com/read/29777999/targeted-delivery-of-cd44s-sirna-by-scfv-overcomes-de-novo-resistance-to-cetuximab-in-triple-negative-breast-cancer
#18
Wenyan Fu, Hefen Sun, Yang Zhao, Mengting Chen, Lipeng Yang, Xueli Yang, Wei Jin
The overexpression of EGFR often occurs in TNBC, and the anti-EGFR receptor antibody cetuximab is used widely to treat metastatic cancer in the clinic. However, EGFR-targeted therapies have been developed for TNBC without clinical success. In this study, we show that impaired EGFR degradation is crucial for resistance to cetuximab, which depends on the cell surface molecule CD44. To further investigate the role of CD44 in EGFR signaling and its treatment potential, we developed a targeting fusion protein composed of an anti-EGFR scFv generated from cetuximab and truncated protamine, called Ce-tP...
May 16, 2018: Molecular Immunology
https://www.readbyqxmd.com/read/29777707/functional-analysis-of-juxta-and-intra-membrane-domains-of-murine-app-by-genome-editing-in-neuro2a-cells
#19
Nanaka Kaneshiro, Ryosuke Imaoka, Masato Komai, Taku Kashiyama, Takashi Sakurai, Takashi Uehara, Nobumasa Takasugi
Amyloid-β precursor protein (APP) correlates with the pathogenesis of certain brain diseases, such as Alzheimer disease (AD). APP is cleaved by several enzymes to produce APP metabolites, including the amyloid beta peptide (Aβ), which accumulates in the brain of AD patients. However, the exact functions of APP metabolites remain elusive. In this study, using genome editing technology, we mutated juxta- and intra-membrane domains of murine APP in the mouse neuroblastoma cell line, Neuro2a. We identified several clones that expressed characteristic patterns of APP metabolites...
May 16, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29777682/inhibition-of-bet-bromodomains-restores-corticosteroid-responsiveness-in-a-mixed-granulocytic-mouse-model-of-asthma
#20
Ahmed Nadeem, Sheikh F Ahmad, Naif O Al-Harbi, Nahid Siddiqui, Khalid E Ibrahim, Sabry M Attia
Asthma is a heterogeneous disease characterized by different endotypes/phenotypes. Th2/Th17 driven mixed granulocytic asthma is one of them and shows resistance to corticosteroid therapy. Bromodomain and extra-terminal (BET) proteins are required for differentiation of Th17 cells which play a pivotal role in neutrophilic inflammation. Therefore, we sought to characterize the differential effects of BET inhibitor versus corticosteroids, and their potential synergism in cockroach allergen extract (CE)-induced mixed granulocytic (eosinophilic and neutrophilic) mouse model of asthma having Th2/Th17 endotype...
May 16, 2018: Biochemical Pharmacology
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