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https://www.readbyqxmd.com/read/28056014/prevalence-of-chagas-disease-in-a-u-s-population-of-latin-american-immigrants-with-conduction-abnormalities-on-electrocardiogram
#1
Mahmoud I Traina, Salvador Hernandez, Daniel R Sanchez, Jalal Dufani, Mohsin Salih, Adieb M Abuhamidah, Wilman Olmedo, Jason S Bradfield, Colin J Forsyth, Sheba K Meymandi
Chagas disease (CD) affects over six million people and is a leading cause of cardiomyopathy in Latin America. Given recent migration trends, there is a large population at risk in the United States (US). Early stage cardiac involvement from CD usually presents with conduction abnormalities on electrocardiogram (ECG) including right bundle branch block (RBBB), left anterior or posterior fascicular block (LAFB or LPFB, respectively), and rarely, left bundle branch block (LBBB). Identification of disease at this stage may lead to early treatment and potentially delay the progression to impaired systolic function...
January 5, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28054710/atypical-surface-ecg-complicating-the-diagnosis-of-bundle-branch-reentry-tachycardia
#2
Christopher Reithmann, Bernhard Herkommer, Thomas Remp, Michael Fiek
BACKGROUND: Typical left bundle branch block (LBBB) during ventricular tachycardia (VT) is a diagnostic criterion of bundle branch reentry tachycardia (BBRT) with activation of the right bundle in the anterograde direction. METHODS AND RESULTS: 11 patients (7 male, 60 ± 12 years) with non-ischemic cardiomyopathy (left ventricular ejection fraction 37 ± 16 %) presenting with BBRT were successfully treated by ablation of the right bundle. Among them, 5 patients had atypical surface ECGs differing from a typical left bundle branch block during the VT...
January 5, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28045723/rate-dependent-left-bundle-branch-block-in-an-ambulatory-surgery-patient-a-case-report
#3
Ashraf Farag, Justin Tsai, Sam Deeb, Deidre Putman-Garcia, John D Wasnick, Lydia A Conlay
A 52-year-old woman, ASA II (American Society of Anesthesia classification II) scheduled for cholecystectomy in an ambulatory center, exhibited a wide-complex tachycardia with ectopy on the monitor after induction with propofol and succinylcholine. Blood pressure remained stable; amiodarone was administered for presumed ventricular tachycardia. A 12-lead electrocardiogram (ECG) showed a new left bundle branch block (LBBB) at 98 beats per minute (bpm), which resolved when the heart rate slowed. Surgery was postponed, and both the LBBB and ectopy recurred frequently during the next 24 hours in the intensive care unit, particularly at heart rates >90 bpm...
December 30, 2016: A & A Case Reports
https://www.readbyqxmd.com/read/28032941/permanent-his-bundle-pacing-the-past-present-and-future
#4
REVIEW
Parikshit S Sharma, Kenneth A Ellenbogen, Richard G Trohman
Long-term right ventricular (RV) apical pacing has been associated with an increased risk of death, heart failure (HF) and atrial fibrillation (AF). Alternative sites for RV pacing have not proven to be superior to right ventricular apical pacing. Cardiac resynchronization therapy (CRT) using a biventricular (BiV) lead system is indicated for patients with a low left ventricular ejection fractions (LVEF) and QRS prolongation, but there remains about a 25-30% non-response rate. CRT has been less effective for non-LBBB conduction delay and with normal/low normal left ventricular (LV) function...
December 29, 2016: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28027906/assessment-of-smith-algorithms-for-the-diagnosis-of-acute-myocardial-infarction-in-the-presence-of-left-bundle-branch-block
#5
Andrea Di Marco, Ignasi Anguera, Marcos Rodríguez, Alessandro Sionis, Antoni Bayes-Genis, Jany Rodríguez, Albert Ariza-Solé, José Carlos Sánchez-Salado, Mario Díaz-Nuila, Mónica Masotti, Roger Villuendas, Paolo Dallaglio, Joan Antoni Gómez-Hospital, Ángel Cequier
INTRODUCTION AND OBJECTIVES: Recently, a new electrocardiography algorithm has shown promising results for the the diagnosis of acute myocardial infarction in the presence of left bundle branch block (LBBB). We aimed to assess these new electrocardiography rules in a cohort of patients referred for primary percutaneous coronary intervention (pPCI). METHODS: Retrospective observational cohort study that included all patients with suspected myocardial infarction and LBBB on the presenting electrocardiogram, referred for pPCI to 4 tertiary hospitals in Barcelona, Spain...
December 24, 2016: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28017393/long-term-outcome-after-crt-in-the-presence-of-mechanical-dyssynchrony-seen-with-chronic-rv-pacing-or-intrinsic-lbbb
#6
Ivan Stankovic, Christian Prinz, Agnieszka Ciarka, Ana Maria Daraban, Yujing Mo, Marit Aarones, Mariola Szulik, Stefan Winter, Aleksandar N Neskovic, Tomasz Kukulski, Svend Aakhus, Rik Willems, Wolfgang Fehske, Martin Penicka, Lothar Faber, Jens-Uwe Voigt
OBJECTIVES: The aim of this study was to compare the volumetric response and the long-term survival after cardiac resynchronization therapy (CRT) in patients with intrinsic left bundle branch block (LBBB) versus chronic right ventricular pacing (RVP) with respect to the presence of mechanical dyssynchrony (MD). BACKGROUND: Chronic RVP induces an iatrogenic LBBB and asynchronous left ventricular contraction that is potentially reversible by upgrading to CRT. METHODS: A total of 914 patients eligible for CRT (117 with conventional pacemakers and 797 with intrinsic LBBB) were included in the study...
December 9, 2016: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28013281/prognostic-usefulness-of-contemporary-stress-echocardiography-in-patients-with-left-bundle-branch-block-and-impact-of-contrast-use-in-improving-prediction-of-outcome
#7
Anastasia Vamvakidou, Nikos Karogiannis, Vasilis Tzalamouras, Guy Parsons, Grace Young, Sothinathan Gurunathan, Roxy Senior
AIMS: Patients with symptomatic left bundle branch block (LBBB) may have myocardial ischaemia due to both coronary artery disease and/or cardiomyopathy (microcirculatory abnormalities) and may have concomitant left ventricular (LV) dysfunction. We aimed to assess the feasibility and prognostic value of contemporary stress echocardiography (SE), which can uncover both pathophysiologies in LBBB patients in routine clinical practice, and also aimed to assess the additive value of contrast SE...
December 24, 2016: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28011837/non-invasive-model-based-measures-of-ventricular-electrical-dyssynchrony-for-predicting-crt-outcomes
#8
Christopher T Villongco, David E Krummen, Jeffrey H Omens, Andrew D McCulloch
AIMS: Left ventricular activation delay due to left bundle branch block (LBBB) is an important determinant of the severity of dyssynchronous heart failure (DHF). We investigated whether patient-specific computational models constructed from non-invasive measurements can provide measures of baseline dyssynchrony and its reduction after CRT that may explain the degree of long-term reverse ventricular remodelling. METHODS AND RESULTS: LV end-systolic volume reduction (ΔESVLV) measured by 2D trans-thoracic echocardiography in eight patients following 6 months of CRT was significantly (P < 0...
December 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28011836/new-insights-from-a-computational-model-on-the-relation-between-pacing-site-and-crt-response
#9
Marieke Pluijmert, Peter H M Bovendeerd, Joost Lumens, Kevin Vernooy, Frits W Prinzen, T Delhaas
AIMS: Cardiac resynchronization therapy (CRT) produces clinical benefits in chronic heart failure patients with left bundle-branch block (LBBB). The position of the pacing site on the left ventricle (LV) is considered an important determinant of CRT response, but the mechanism how the LV pacing site determines CRT response is not completely understood. The objective of this study is to investigate the relation between LV pacing site during biventricular (BiV) pacing and cardiac function...
December 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28011830/electrical-remodelling-in-patients-with-iatrogenic-left-bundle-branch-block
#10
Elien B Engels, Thomas T Poels, Patrick Houthuizen, Peter P T de Jaegere, Jos G Maessen, Kevin Vernooy, Frits W Prinzen
AIMS: Left bundle branch block (LBBB) is induced in approximately one-third of all transcatheter aortic valve implantation (TAVI) procedures. We investigated electrophysiological remodelling in patients with TAVI-induced LBBB. METHODS AND RESULTS: This retrospective study comprises 107 patients with initially narrow QRS complex of whom 40 did not and 67 did develop persistent LBBB after TAVI. 12-lead electrocardiograms (ECGs) taken before TAVI, within 24 hours ('acute'), and 1-12 months after TAVI ('chronic') were used to reconstruct vectorcardiograms...
December 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28009943/corevalve-prosthesis-depth-what-is-the-optimal-measurement-target
#11
Rafael Wolff, Sam Radhakrishnan, Hirotsugu Mitsuhashi, Anna Zavodni, Idan Roifman, John D Sparkes, Stephen E Fremes, Sabina Bakar-Irwin, Mark S Hansen, Bradley H Strauss
BACKGROUND: A major drawback of the transcatheter aortic valve replacement (TAVR) procedure using the self-expandable Medtronic CoreValve (MCV) prosthesis is the high incidence of conduction disturbances and the need for postprocedural permanent pacemaker (PPM) implantation. The depth of prosthesis implantation may be an important contributing factor. The study aim was to determine the relationship between angiographic measurements of the MCV prosthesis depth and the occurrence of new conduction disturbances and need for PPM after TAVR...
July 2016: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/27993910/a-38-year-old-man-with-progressive-dyspnoea-and-ventricular-tachycardia
#12
Alphonsus C Liew, Claire E Raphael, Raad Mohiaddin
CLINICAL INTRODUCTION: A previously healthy 38-year-old man presented with a 3-month history of progressive dyspnoea and ventricular tachycardia (VT). He suffered a viral illness 4 months earlier. There was no family history of cardiac disease or sudden cardiac death (SCD). ECG showed left bundle branch block (LBBB). Echocardiography revealed a dilated left ventricle with severely impaired systolic function. Coronary angiogram showed angiographically normal coronary arteries. He was diagnosed as having dilated cardiomyopathy and was referred for further assessment with cardiovascular magnetic resonance (CMR) (figure 1) and subsequently CT thorax...
December 19, 2016: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/27989791/coronary-sinus-activation-patterns-in-patients-with-and-without-left-bundle-branch-block-undergoing-electroanatomic-mapping-system-guided-cardiac-resynchronization-therapy-device-implantation
#13
Maurizio Del Greco, Alessandro Zorzi, Irene Di Matteo, Anna Cima, Massimiliano Maines, Carlo Angheben, Domenico Catanzariti
BACKGROUND: implantation of the left ventricular (LV) lead in segments with delayed electrical activation may improve response to cardiac resynchronization therapy (CRT). OBJECTIVE: to evaluate amount and regional distribution of LV electrical delay (LVED) in patients with or without left bundle branch block (LBBB). METHODS: we enrolled 60 patients who underwent electroanatomic mapping system-guided CRT implantation. Activation mapping of the coronary sinus (CS) branches was performed using an insulated guide wire...
October 27, 2016: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/27987072/the-value-of-electrophysiologic-study-in-decision-making-regarding-the-need-for-pacemaker-implantation-after-tavi
#14
Oholi Tovia-Brodie, Yael Ben-Haim, Erel Joffe, Ariel Finkelstein, Aharon Glick, Raphael Rosso, Bernard Belhassen, Yoav Michowitz
PURPOSE: The purpose of this study was to evaluate electrophysiologic study (EPS) in risk stratification of relative indications for pacemaker implantation (PMI) after transcatheter aortic valve implantation (TAVI). METHODS: We reviewed files of all patients who had a left bundle branch block (LBBB) and underwent EPS after TAVI between 3/2009 and 5/2015. The indications for EPS were new-onset LBBB and the presence of an old or a new-onset LBBB associated with either PR prolongation after TAVI (∆PR >20 ms) or with "slow" atrial fibrillation (<100/min)...
December 17, 2016: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/27965025/cardiovascular-outcomes-in-patients-with-intraventricular-conduction-blocks-sixteen-year-follow-up-in-a-statewide-database
#15
John S Pantazopoulos, Alice David, William J Kostis, Nora M Cosgrove, John B Kostis
BACKGROUND: To assess the adverse clinical effects of left anterior hemiblock alove or in combination with right bundle branch block and of complete left bundle branch block in comparison with isolated right bundle branch block, and relate these effects to altered mechanoelectric factors resulting in left ventricular dysfunction. METHODS: In a 16-year follow-up of a statewide database, we studied the occurrence of mortal and morbid cardiovascular (CV) events among patients without apparent ischemic heart disease who had left anterior hemiblock (LAHB, n=4273, right bundle branch block (RBBB) with LAHB (BFBB, n=1857) and left bundle branch block (LBBB, n=9484 as compared to isolated RBBB (n=25288)...
December 10, 2016: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
https://www.readbyqxmd.com/read/27955885/the-prognostic-value-of-a-new-left-bundle-branch-block-in-patients-with-acute-myocardial-infarction-a-systematic-review-and-meta-analysis
#16
Belal Al Rajoub, Samar Noureddine, Samer El Chami, Mohamad Hussein Haidar, Bachir Itani, Aida Zaiter, Elie A Akl
OBJECTIVE: To assess the prognostic value of new left bundle branch block (LBBB) in patients with acute myocardial infarction (AMI). BACKGROUND: LBBB develops in many cardiac conditions, including AMI. The empirical evidence for the contribution of LBBB to mortality in AMI is not consistent. METHODS: Medline, PubMed, CINAHL, and EMBASE were searched. Inverse variance meta-analysis was performed with odds ratios as the effect estimates. The I(2) statistic and risk of bias were assessed...
December 10, 2016: Heart & Lung: the Journal of Critical Care
https://www.readbyqxmd.com/read/27943488/electrocardiographic-predictors-of-long-term-cardiac-pacing-dependency-following-transcatheter-aortic-valve-implantation
#17
Sivan Naveh, Gidon Y Perlman, Yair Elitsur, David Planer, Dan Gilon, David Leibowitz, Chaim Lotan, Haim Danenberg, Ronny Alcalai
BACKGROUND: Conduction disorders requiring permanent pacemaker (PPM) implantation are a known complication of trans-catheter aortic valve implantation (TAVI). Indications for permanent pacing in this setting are still controversial. The study aim was to characterize the natural history of conduction disorders related to TAVI, and to identify predictors for long term pacing dependency. METHODS: Consecutive patients who underwent TAVI were included in this prospective observational study...
December 12, 2016: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/27890282/selective-versus-non-selective-his-bundle-pacing-for-cardiac-resynchronization-therapy
#18
REVIEW
Gaurav A Upadhyay, Roderick Tung
Cardiac resynchronization therapy (CRT) has an established role in the device-based therapy for patients with systolic dysfunction and intraventricular conduction delay, particularly left bundle branch block (LBBB). Recently, His bundle pacing (HBP) has emerged as a viable alternative for resynchronization which can successfully narrow surface QRS and improve mechanical dyssynchrony. The role of selective (i.e., an isoelectric His-paced to QRS interval similar to native HV interval) versus non-selective capture (i...
October 18, 2016: Journal of Electrocardiology
https://www.readbyqxmd.com/read/27886918/cardiac-resynchronization-therapy-an-overview-on-guidelines
#19
REVIEW
Giuseppe Boriani, Martina Nesti, Matteo Ziacchi, Luigi Padeletti
Cardiac resynchronization therapy (CRT) is included in international consensus guidelines as a treatment with proven efficacy in well-selected patients on top of optimal medical therapy. Although all the guidelines strongly recommend CRT for LBBB with QRS duration greater than 150 milliseconds, lower strength of recommendation is reported for QRS duration of 120 to 150 milliseconds, especially if not associated with LBBB. CRT is not recommended for a QRS of less than 120 milliseconds. No indication emerges for guiding the implant based on echocardiographic evaluation of dyssynchrony...
January 2017: Heart Failure Clinics
https://www.readbyqxmd.com/read/27885752/biventricular-paced-qrs-area-predicts-acute-hemodynamic-crt-response-better-than-qrs-duration-or-qrs-amplitudes
#20
Jan DE Pooter, Milad El Haddad, Marc DE Buyzere, Hernandez Alfonso Aranda, Richard Cornelussen, Berthold Stegemann, Christopher A Rinaldi, Maciej Sterlinski, Adam Sokal, Darrel P Francis, Luc Jordaens, Roland X Stroobandt, Frederic VAN Heuverswyn, Frank Timmermans
INTRODUCTION: Vectorcardiographic (VCG) QRS area of left bundle branch block (LBBB) predicts acute hemodynamic response in cardiac resynchronization therapy (CRT) patients. We hypothesized that changes in QRS area occurring with biventricular pacing (BV) might predict acute hemodynamic CRT response (AHR). METHODS AND RESULTS: VCGs of 624 BV paced electrocardiograms (25 LBBB patients with 35 different pacing configurations) were calculated according to Frank's orthogonal lead system...
November 25, 2016: Journal of Cardiovascular Electrophysiology
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