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https://www.readbyqxmd.com/read/28538477/implementing-immediate-postpartum-long-acting-reversible-contraception-programs
#1
Katherine W McHugh, Brownsyne Tucker Edmonds, Elizabeth Ferries-Rowe, David M Haas
No abstract text is available yet for this article.
June 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28538285/teenage-pregnancy-prevention-the-role-of-young-men
#2
Gabriela Vargas, Joshua Borus, Brittany M Charlton
PURPOSE OF REVIEW: Although teenage pregnancy is declining in many parts of the world, it remains associated with considerable social, health, and economic outcomes. Pregnancy prevention efforts focus primarily on young women, with minimal attention to young men. This review highlights recent literature pertaining to the role of young men in pregnancy prevention. RECENT FINDINGS: Young men have varying views on contraception as well as which partner(s) should be responsible for its use...
May 22, 2017: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/28537948/current-techniques-and-outcomes-in-hysteroscopic-sterilization-current-evidence-considerations-and-complications-with-hysteroscopic-sterilization-micro-inserts
#3
James Casey, Laura Cedo-Cintron, Jessica Pearce, Amanda Yunker
PURPOSE OF REVIEW: To describe the current data regarding effectiveness, complications, postoperative evaluation, and surgical interventions associated with Essure hysteroscopic sterilization. RECENT FINDINGS: Hysteroscopic sterilization is a commonly performed procedure that is offered as a well tolerated, effective, outpatient method of permanent sterilization. Over the past several years, concerns have been raised regarding correct placement and postoperative complications...
May 19, 2017: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28535045/bet-bromodomain-inhibitors-with-one-step-synthesis-discovered-from-virtual-screen
#4
Alex M Ayoub, Laura M L Hawk, Ryan J Herzig, Jiewei Jiang, Andrea J Wisniewski, Clifford T Gee, Peiliang Zhao, Jin-Yi Zhu, Norbert Berndt, Nana K Offei-Addo, Thomas G Scott, Jun Qi, James E Bradner, Timothy R Ward, Ernst Schönbrunn, Gunda I Georg, William C K Pomerantz
Chemical inhibition of epigenetic regulatory proteins BrdT and Brd4 is emerging as a promising therapeutic strategy in contraception, cancer, and heart disease. We report an easily synthesized dihydropyridopyrmidine pan-BET inhibitor scaffold, which was uncovered via a virtual screen followed by testing in a fluorescence anisotropy assay. Dihydropyridpyimidine 3 was subjected to further characterization and is highly selective for the BET family of bromodomains. Structure-activity relationship data and ligand deconstruction highlight the importance of the substitution of the uracil moiety for potency and selectivity...
May 23, 2017: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28534697/pregnancy-outcome-of-laparoscopic-tubal-reanastomosis-retrospective-results-from-a-single-clinical-centre
#5
Rana Karayalcin, Sarp Ozcan, Aytekin Tokmak, Beril Gürlek, Okan Yenicesu, Hakan Timur
Objective Tubal sterilization is a widespread method of contraception. Post-sterilization regret is encountered, despite careful consideration prior to the procedure. Two treatment options are available for women after having had tubal sterilization: microsurgical reversal and IVF treatment. Recent improvements in laparoscopy have allowed tubal reanastomosis to be performed. This study aimed to evaluate the reproductive outcome after laparoscopic tubal reanastomosis and surgical features of the patients. Methods From June 2007 to January 2010, 27 patients with bilateral tubal ligation who underwent laparoscopic tubal reanastomosis were evaluated retrospectively...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28534019/migration-of-a-contraceptive-subdermal-device-into-the-lung
#6
Ji Hui Choi, Ha-Yeon Kim, Sung Soo Lee, SiHyun Cho
A single-rod subdermal contraceptive implant is usually located around the insertion site, has been usually known to migrate within less than 2 cm of the insertion site and the true migration over 2 cm has been rarely reported. We report a case of migrated radiopaque subdermal contraceptive implant into lung in a 37-year-old woman. On conducted chest computed tomography, subdermal contraceptive implant was in subsegmental branch in left posterior basal segment of lung. Removal of subdermal contraceptive implant in left posterior basal segment of lung by mini-thoracotomy was performed by a chest surgeon...
May 2017: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/28533198/chlamydia-and-hiv-testing-contraception-advice-and-free-condoms-offered-in-general-practice-a-qualitative-interview-study-of-young-adults-perceptions-of-this-initiative
#7
Leah Ffion Jones, Ellie Ricketts, Katy Town, Claire Rugman, Donna Lecky, Kate Folkard, Anthony Nardone, Thomas Nathan Hartney, Cliodna McNulty
BACKGROUND: Opportunistic chlamydia screening is actively encouraged in English general practices. Based on recent policy changes, Public Health England piloted 3Cs and HIV in 2013-2014, integrating the offer of chlamydia testing with providing condoms, contraceptive information, and HIV testing (referred to as 3Cs and HIV) according to national guidelines. AIM: To determine young adults' opinions of receiving a broader sexual health offer of 3Cs and HIV at their GP practice...
May 22, 2017: British Journal of General Practice: the Journal of the Royal College of General Practitioners
https://www.readbyqxmd.com/read/28532270/predominant-contributions-of-carboxylesterase-1-and-2-in-hydrolysis-of-anordrin-in-humans
#8
Jinfang Jiang, Xiaoyan Chen, Dafang Zhong
1. Anordrin (2α, 17α-diethynyl-A-nor-5α-androstane-2β, 17β-diol diproprionate) is post-coital contraceptive drug that is on the market in China for more than 30 years. This study aims to elucidate enzymes involved in anordrin hydrolysis, and to evaluate the significant role of carboxylesterases in anordrin hydrolysis in humans. 2. Human liver and intestinal microsomes, recombinant human carboxylesterase were selected as enzyme sources. In human liver microsomes, intrinsic clearance was 684 ± 83 μL/min/mg protein, which was considerably higher than the value of intestine microsomes (94...
May 22, 2017: Xenobiotica; the Fate of Foreign Compounds in Biological Systems
https://www.readbyqxmd.com/read/28530033/concomitant-contraceptive-implant-and-efavirenz-use-in-women-living-with-hiv-perspectives-on-current-evidence-and-policy-implications-for-family-planning-and-hiv-treatment-guidelines
#9
REVIEW
Rena C Patel, Chelsea Morroni, Kimberly K Scarsi, Tabitha Sripipatana, James Kiarie, Craig R Cohen
INTRODUCTION: Preventing unintended pregnancies is important among all women, including those living with HIV. Increasing numbers of women, including HIV-positive women, choose progestin-containing subdermal implants, which are one of the most effective forms of contraception. However, drug-drug interactions between contraceptive hormones and efavirenz-based antiretroviral therapy (ART) may reduce implant effectiveness. We present four inter-related perspectives on this issue. DISCUSSION: First, as a case study, we discuss how limited data prompted country-level guidance against the use of implants among women concomitantly using efavirenz in South Africa and its subsequent negative effects on the use of implants in general...
May 11, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28529751/comparison-of-lifestyle-hormonal-and-medical-factors-in-women-with-sporadic-and-lynch-syndrome-associated-endometrial-cancer-a-retrospective-case-case-study
#10
Mari H Aaltonen, Synnöve Staff, Jukka-Pekka Mecklin, Kirsi Pylvänäinen, Johanna U Mäenpää
Data available on lifestyle-associated hormonal and medical factors among endometrial cancer (EC)-affected women who carry the Lynch Syndrome (LS) mutation is limited. The aim of the present retrospective case study was to compare the reproductive and medical history, as well as lifestyle-associated factors, among patients with LS and sporadic EC. The study population consisted of 50 verified germline mismatch repair (MMR) gene mutation carriers diagnosed with EC, and 110 sporadic EC patients. Data were collected using postal questionnaires...
May 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28529362/study-of-sexual-functioning-and-disorder-in-women-before-and-after-tubal-sterilization-tubectomy
#11
Shweta Patil Kunkeri, T S Sathyanarayana Rao, Chittaranjan Andrade
INTRODUCTION: Sexual relationship is a basis for mental health and continuity of the healthy generation. There are very few studies on the female sexual functioning, especially in India. Sterilization being the most common contraceptive method, sexual functioning in women undergoing this surgical intervention has not been adequately explored. Available studies have found conflicting results; some have reported that sterilization has positive effects on sexual functioning since anxiety of getting pregnant is abolished...
January 2017: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/28527856/a-bloody-mess
#12
Michael C Brodsky, Valérie Biousse
A 15-year-old girl presented with a unilateral sixth nerve palsy and papilledema following a severe headache. MR imaging showed thrombosis of the superior sagittal sinus and proximal right transverse sinus that were attributed to oral contraceptive use after a coagulation workup was negative. Systemic anticoagulation caused a hemorrhagic papillopathy in both eyes, raising the question as to whether anticoagulation should be discontinued. Diagnostic and management issues regarding cerebral venous sinus thrombosis with secondary intracranial hypertension are discussed...
May 17, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28527670/vulvar-fibroepithelial-polyps-in-an-adolescent-female
#13
Jonathan Avila, Kathleen Nicol, Steven C Matson
BACKGROUND: Fibroepithelial polyps (FEPs) are benign tumors, of possibly hormone-dependent nature, found in the vulvovaginal region of women of reproductive age. CASE: A 15-year-old adolescent girl, on hormonal contraceptive therapy, who presented with multiple vulvar masses with histopathology consistent with FEP. SUMMARY AND CONCLUSION: The spectrum of the morphology of FEPs may make their diagnosis challenging. We describe a rare presentation of vulvar fibroepithelial polyps in an adolescent girl on hormonal contraceptive therapy...
May 17, 2017: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/28527612/intrauterine-contraception-underestimated-and-underutilized
#14
Robert L Reid
No abstract text is available yet for this article.
June 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28527064/treating-migraine-with-contraceptives
#15
Gianni Allais, Giulia Chiarle, Silvia Sinigaglia, Gisella Airola, Paola Schiapparelli, Fabiola Bergandi, Chiara Benedetto
At least 18% of women suffers from migraine. Clinically, there are two main forms of migraine: migraine with aura (MA) and migraine without aura (MO) and more than 50% of MO is strongly correlated to the menstrual cycle. The high prevalence of migraine in females, its correlation with the menstrual cycle and with the use of combined hormonal contraceptives (CHCs) suggest that the estrogen drop is implicated in the pathogenesis of the attacks. Although CHCs may trigger or worsen migraine, their correct use may even prevent or reduce some forms of migraine, like estrogen withdrawal headache...
May 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28526078/the-efficacy-of-chlorhexidine-gel-in-the-prevention-of-alveolar-osteitis-after-mandibular-third-molar-extraction-a-systematic-review-and-meta-analysis
#16
Amare Teshome
BACKGROUND: Alveolar osteitis is a very painful and distressing condition for a patient who has recently undergone a tooth extraction and has led dental professionals to search for preventive measures. The aim of this meta-analysis to determine the effect of chlorhexidine (CHX) gel on the incidence of alveolar osteitis after mandibular third molar extraction. METHODS: Studies were searched for on electronic search engines using Medline (PubMed), Cochrane central, Scopus and advanced Google Scholar from May 2015 to December 2015...
May 19, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28525397/an-unusual-case-of-sudden-death-is-there-a-relationship-between-thyroid-disorders-and-fatal-pulmonary-thromboembolism-a-case-report-and-review-of-literature
#17
Isabella Aquila, Silvia Boca, Fiorella Caputo, Matteo A Sacco, Santo Gratteri, Vittorio Fineschi, Pietrantonio Ricci
In adults, the most common cause of sudden death is coronary heart disease or defects in the cardiac conduction system; however, there are many cases of sudden death occurring from other causes such as fatal pulmonary thromboembolism. Several risk factors are recognized, including hospitalization, surgery, obesity, pregnancy, the use of oral contraceptives, traumatic fractures, and genetic conditions, which cause hypercoagulable states such as factor V Leiden mutations. Although many risk factors have been identified, the mortality rate is still high...
May 19, 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28524747/health-care-students-at-an-argentinean-school-of-medicine-are-they-well-prepared-to-provide-quality-sexual-and-reproductive-health-services
#18
Belén Provenzano-Castro, Silvia Oizerovich, Babill Stray-Pedersen
OBJECTIVES: The aim of our study was to assess what students of the University of Buenos Aires School of Medicine learn about sexual and reproductive health (SRH) and rights, focusing particularly on their knowledge of accessibility to contraception and abortion legislation. METHODS: In this cross-sectional study, self-administered, anonymous questionnaires were administered to 760 first year students and to 695 final year students from different fields of study (medicine, midwifery, nursing, radiology, nutrition, speech therapy and physiotherapy) between 2011 and 2013...
May 19, 2017: European Journal of Contraception & Reproductive Health Care
https://www.readbyqxmd.com/read/28524326/family-planning-knowledge-and-use-among-women-in-camps-for-internally-displaced-people-in-the-democratic-republic-of-the-congo
#19
Rogatien M Kisindja, Christophe Kimona, Modestine Etoy, Florby Dorme, Nerys Benfield
OBJECTIVE: To describe family planning awareness and needs among internally displaced women residing in the Mugunga camps in North Kivu, eastern Democratic Republic of the Congo. METHODS: A cross-sectional survey of women aged 14-45 years residing in the Mugunga camps was conducted during March 2014. The verbally administered survey assessed participants' obstetric history and their family planning knowledge, interest, and use. Descriptive statistics were obtained...
May 19, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28524239/oral-contraceptive-pills-risky-or-protective-in-case-of-trichinella-spiralis-infection
#20
Marwa A Hasby Saad, Dina A Radi, Eiman A Hasby
AIM: to investigate how Trichinella spiralis infection can be affected by contraceptive pills invivo. METHODS: included six groups of female Wistar rats; healthy, Trichinella infected, receiving combined contraceptive pills (COCPs), receiving progestin only pills (POPs), infected receiving COCPs and infected receiving POPs. Parasite burden was measured (two gender worm counts, gravidity, larvae/muscle and RCI). Histopathological examination, immunohistochemical detection of C-kit mast cells & Foxp3+ T-reg...
May 19, 2017: Parasite Immunology
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