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https://www.readbyqxmd.com/read/28109164/assessment-of-biological-psychological-and-adherence-factors-in-the-prediction-of-step-down-treatment-for-patients-with-well-controlled-asthma
#1
Norihiro Saito, Akihito Kamata, Masamichi Itoga, Mami Tamaki, Hiroyuki Kayaba, Thomas Ritz
OBJECTIVES: Inhaled corticosteroids (ICS) and inhaled corticosteroids combined with long-acting beta2-agonist (ICS/LABA) are standard treatments for asthma. However, factors that might help reduce medication in well-controlled asthma are unknown. We classified problems of asthma patients into biological, psychological and adherence factors, and investigated factors associated with the indication and failure of a medication step-down treatment. METHODS: Two hundred twenty two well-controlled asthma patients receiving ICS or ICS/LABA were assessed for physical and psychiatric problems and followed up for one year from adjustment of their treatment step...
January 21, 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28109109/-role-of-camp-creb-bdnf-signaling-pathway-in-anti-depressive-effect-of-vortioxetine-in-mice
#2
Hui Yu, Jia-Jia Chen, Bing-Qing Zeng, Qiu-Ping Zhong, Jiang-Ping Xu, Yong-Gang Liu
OBJECTIVE: To investigate the effects of vortioxetine on cAMP/CREB/BDNF signal pathway. METHODS: Forty Kunming mice were randomized into control group and chronic unpredictable mild stress (CUMS) group. After establishment of depressive models verified by sucrose preference test, the mice in CUMS group were divided into model group, fluoxetine group and vortioxetine group. The antidepressive effect of vortioxetine was analyzed by tail suspension test, forced swim test and open field test...
January 20, 2017: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/28108358/neurochemical-and-metabolic-effects-of-acute-and-chronic-alcohol-in-the-human-brain-studies-with-positron-emission-tomography
#3
REVIEW
Nora D Volkow, Corinde E Wiers, Ehsan Shokri-Kojori, Dardo Tomasi, Gene-Jack Wang, Ruben Baler
The use of Positron emission tomography (PET) to study the effects of acute and chronic alcohol on the human brain has enhanced our understanding of the mechanisms underlying alcohol's rewarding effects, the neuroadaptations from chronic exposure that contribute to tolerance and withdrawal, and the changes in fronto-striatal circuits that lead to loss of control and enhanced motivation to drink that characterize alcohol use disorders (AUD). These include studies showing that alcohol's reinforcing effects may result not only from its enhancement of dopaminergic, GABAergic and opioid signaling but also from its caloric properties...
January 17, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/28108322/effect-of-zbd-2-on-chronic-pain-depressive-like-behaviors-and-recovery-of-motor-function-following-spinal-cord-injury-in-mice
#4
Xiao-Ming Li, Jia Meng, Lin Tao Li, Ting Guo, Liu-Kun Yang, Qi-Xin Shi, Xu-Bo Li, Yong Chen, Qi Yang, Jian-Ning Zhao
In addition to debilitating sensory and motor deficits, patients with spinal cord injury (SCI) may experience chronic hyperpathic pain (SCI-pain). Recent studies have revealed that translocator protein (TSPO) is involved in repairing neural cells as well as reducing anxiety and depression. However, the role of TSPO in SCI-pain and pain-induced depression remains unknown. The present study aimed to determine the effects of a new TSPO ligand, ZBD-2, on SCI-pain and consequent pain-induced depressive-like behaviors in mice...
January 17, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28108209/the-impact-of-cognitive-impairment-on-efficacy-of-pulmonary-rehabilitation-in-patients-with-copd
#5
Fiona A H M Cleutjens, Martijn A Spruit, Rudolf W H M Ponds, Lowie E G W Vanfleteren, Frits M E Franssen, Jeanette B Dijkstra, Candy Gijsen, Emiel F M Wouters, Daisy J A Janssen
OBJECTIVES: To compare changes in pulmonary rehabilitation (PR) dropout and outcomes between chronic obstructive pulmonary disease (COPD) patients with and without cognitive impairment. DESIGN: A cross-sectional observational study. SETTING: Patients with COPD were recruited from a PR centre in the Netherlands. PARTICIPANTS: The study population consisted of 157 patients with clinically stable COPD who were referred for and completed PR...
January 17, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28107900/quality-of-sleep-in-renal-transplant-recipients-and-patients-on-hemodialysis
#6
Paraskevi G Liaveri, Dimitris Dikeos, Ioannis Ilias, Eirini P Lygkoni, Ioannis N Boletis, Chryssanthi Skalioti, Thomas Paparrigopoulos
BACKGROUND: Sleep disorders are very common in patients with chronic kidney disease and they may not always subside after kidney transplantation. AIM AND METHODS: The aim of this cross-sectional study was to evaluate the self-reported quality of sleep, insomnia problems in particular, and examine the factors that disturb sleep of kidney transplant recipients (KTx: n=152) in comparison to age- and sex-matched patients on dialysis (HD: n=67) and participants with normal renal function (NOR: n=49), through the administration of the Athens Insomnia Scale (AIS) at least six months after transplantation...
February 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28107898/the-experience-of-pain-severity-and-pain-interference-in-vulvodynia-patients-the-role-of-cognitive-behavioural-factors-psychological-distress-and-fatigue
#7
Claudia Chisari, Joseph Chilcot
OBJECTIVE: Vulvodynia is a chronic pain condition characterised by severe pain affecting the vulva. Biopsychosocial models have revealed the importance of illness perceptions, cognitive-behavioural variables and psychological distress in explaining the experience of pain and disability across several conditions. These factors have never been collectively examined in vulvodynia. We predicted that distress, fatigue, illness perceptions, and cognitive-behavioural factors would be associated with pain severity and interference among women with vulvodynia...
February 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28107894/heart-rate-variability-biofeedback-therapy-and-graded-exercise-training-in-management-of-chronic-fatigue-syndrome-an-exploratory-pilot-study
#8
Petra Windthorst, Nazar Mazurak, Marvin Kuske, Arno Hipp, Katrin E Giel, Paul Enck, Andreas Nieß, Stephan Zipfel, Martin Teufel
OBJECTIVE: Chronic fatigue syndrome (CFS) is characterised by persistent fatigue, exhaustion, and several physical complaints. Research has shown cognitive behavioural therapy (CBT) and graded exercise training (GET) to be the most effective treatments. In a first step we aimed to assess the efficacy of heart rate variability biofeedback therapy (HRV-BF) as a treatment method comprising cognitive and behavioural strategies and GET in the pilot trial. In a second step we aimed to compare both interventions with regard to specific parameters...
February 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28107890/affective-impairment-in-chronic-low-blood-pressure
#9
Stefan Duschek, Alexandra Hoffmann, Gustavo A Reyes Del Paso
OBJECTIVE: Physical complaints such as faintness, dizziness, cold limbs and headaches have been well-established in chronic low blood pressure (hypotension). This study investigated the occurrence of adverse emotional states and the symptoms of depression in this condition. As autonomic dysregulation, particularly diminished sympathetic tone, is believed to be involved in the etiology of hypotension, the impact of different facets of autonomic cardiovascular control on mood and depressive symptoms was also explored...
February 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28107599/the-prevalence-and-impact-of-chronic-neuropathic-pain-on-daily-and-social-life-a-nationwide-study-in-a-japanese-population
#10
S Inoue, T Taguchi, T Yamashita, M Nakamura, T Ushida
BACKGROUND: This study marks the first epidemiological evaluation of the prevalence and burden of chronic neuropathic pain (NeP) in an Asian population. The objective of this nationwide cross-sectional study was to identify the characteristics of individuals with NeP, detect the NeP features that affect their quality of life (QOL), and demonstrate the negative effects of NeP on social and daily living as well as comorbidities including depression, anxiety and sleep disorders. METHODS: We mailed a cross-sectional, population-based epidemiological survey to a random nationwide sample of 10,000 Japanese adults over 20 years old...
January 20, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/28107456/social-inequalities-and-depressive-symptoms-in-adults-the-role-of-objective-and-subjective-socioeconomic-status
#11
Jens Hoebel, Ulrike E Maske, Hajo Zeeb, Thomas Lampert
BACKGROUND: There is substantial evidence that lower objective socioeconomic status (SES)-as measured by education, occupation, and income-is associated with a higher risk of depression. Less is known, however, about associations between perceptions of social status and the prevalence of depression. This study investigated associations of both objective SES and subjective social status (SSS) with depressive symptoms among adults in Germany. METHODS: Data were obtained from the 2013 special wave of the German Health Update study, a national health survey of the adult population in Germany...
2017: PloS One
https://www.readbyqxmd.com/read/28106666/a-tailored-guided-internet-based-cognitive-behavioral-intervention-for-patients-with-rheumatoid-arthritis-as-an-adjunct-to-standard-rheumatological-care-results-of-a-randomized-controlled-trial
#12
M Ferwerda, S van Beugen, H van Middendorp, S Spillekom-van Koulil, A R T Donders, H Visser, E Taal, M C W Creemers, P C L M van Riel, A W M Evers
For patients with chronic pain conditions such as rheumatoid arthritis (RA), who experience elevated levels of distress, tailored guided internet-based cognitive behavioral treatment may be effective in improving psychological and physical functioning, and reducing impact the impact of RA on daily life. A multicenter randomized controlled trial was conducted for RA patients with elevated levels of distress asassessed by a disease-specific measure. The control group (n=71) received standard care and the intervention group (n= 62) additionally received an internet-based tailored cognitive-behavioral intervention...
January 12, 2017: Pain
https://www.readbyqxmd.com/read/28104985/high-risk-of-temporomandibular-disorder-in-irritable-bowel-syndrome-is-there-a-correlation-with-greater-illness-severity
#13
Serena Gallotta, Vincenzo Bruno, Santo Catapano, Nicola Mobilio, Carolina Ciacci, Paola Iovino
AIM: To investigate the prevalence and the risk of temporomandibular disorders (TMDs) in patients with irritable bowel syndrome (IBS) (including each subtype: constipation, diarrhoea, and mixed) compared to the general population. METHODS: Between January 2014 and December 2015 we enrolled consecutively adult patients diagnosed with IBS at the outpatient clinic of the University of Salerno and healthy controls (HC) without IBS. At enrollment, we analyzed all patients for the presence of TMDs according to the Research Diagnostic Criteria for TMD...
January 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28104602/happiness-rather-than-depression-is-associated-with-sexual-behaviour-in-partnered-older-adults
#14
Rosanne Freak-Poli, Gustavo De Castro Lima, Nese Direk, Loes Jaspers, Marian Pitts, Albert Hofman, Henning Tiemeier
BACKGROUND: the relation between positive psychological well-being (PPWB) and sexual behaviour is understudied in older adult groups. OBJECTIVE: to examine the relation between PPWB (positive affect and life satisfaction) and sexual behaviour (sexual activity and physical tenderness) in older adults, and whether it is independent from depressive symptoms and uniform across older age groups. DESIGN: cross-sectional. SETTING: community-dwelling adults aged 65 years or older, Rotterdam, The Netherlands...
October 25, 2016: Age and Ageing
https://www.readbyqxmd.com/read/28104446/factors-associated-with-fear-of-falling-in-community-dwelling-older-adults-with-and-without-diabetes-mellitus-findings-from-the-frailty-in-brazilian-older-people-study-fibra-br
#15
Bruno de Souza Moreira, Rosana Ferreira Sampaio, Juliano Bergamaschine Mata Diz, Alessandra de Carvalho Bastone, Eduardo Ferriolli, Anita Liberalesso Neri, Roberto Alves Lourenço, Rosângela Corrêa Dias, Renata Noce Kirkwood
PURPOSE: This study aimed to investigate the associated factors with fear of falling in community-dwelling older adults with and without diabetes mellitus. METHODS: Data from the Frailty in Brazilian Older People Study (FIBRA-BR), involving 4449 individuals aged 65years or older (19.2% with diabetes), were analyzed. The potential factors associated with fear of falling included sociodemographic data, chronic diseases, health-related variables and functional capacity measures...
January 16, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28104294/rodent-models-of-depression-cardiovascular-comorbidity-bridging-the-known-to-the-new
#16
REVIEW
Luca Carnevali, Nicola Montano, Rosario Statello, Andrea Sgoifo
Numerous epidemiological studies have demonstrated a close and bidirectional association between depression and cardiovascular disorders (CVD). This comorbidity places a significant burden on individuals and the healthcare system. Not surprisingly, in the last two decades preclinical research in the field of depression and CVD has rapidly progressed. Multiple studies have demonstrated that aspects of human depression/cardiovascular comorbidity can be modeled in rodents exposed to chronic stress paradigms and that a depressive-like syndrome can be induced in rodent models of CVD...
January 16, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28102896/impact-of-pre-transplant-depression-on-outcomes-of-allogeneic-and-autologous-hematopoietic-stem-cell-transplantation
#17
Areej El-Jawahri, Yi-Bin Chen, Ruta Brazauskas, Naya He, Stephanie J Lee, Jennifer M Knight, Navneet Majhail, David Buchbinder, Raquel M Schears, Baldeep M Wirk, William A Wood, Ibrahim Ahmed, Mahmoud Aljurf, Jeff Szer, Sara M Beattie, Minoo Battiwalla, Christopher Dandoy, Miguel-Angel Diaz, Anita D'Souza, Cesar O Freytes, James Gajewski, Usama Gergis, Shahrukh K Hashmi, Ann Jakubowski, Rammurti T Kamble, Tamila Kindwall-Keller, Hilard M Lazarus, Adriana K Malone, David I Marks, Kenneth Meehan, Bipin N Savani, Richard F Olsson, David Rizzieri, Amir Steinberg, Dawn Speckhart, David Szwajcer, Helene Schoemans, Sachiko Seo, Celalettin Ustun, Yoshiko Atsuta, Jignesh Dalal, Carmem Sales-Bonfim, Nandita Khera, Theresa Hahn, Wael Saber
BACKGROUND: To evaluate the impact of depression before autologous and allogeneic hematopoietic cell transplantation (HCT) on clinical outcomes posttransplantation. METHODS: We analyzed data from the Center for International Blood and Marrow Transplant Research to compare outcomes after autologous (n = 3786) or allogeneic (n = 7433) HCT for adult patients with hematologic malignancies with an existing diagnosis of pre-HCT depression requiring treatment versus those without pre-HCT depression...
January 19, 2017: Cancer
https://www.readbyqxmd.com/read/28102877/feasibility-acceptability-and-construct-validity-of-eq-5d-in-systemic-sclerosis
#18
Roberta Gualtierotti, Francesca Ingegnoli, Luciana Scalone, Paolo Cortesi, Eleonora Bruschi, Maria Gerosa, Pier Luigi Meroni
BACKGROUND: Systemic sclerosis is a chronic disabling disease that is often associated with severe physical and psychological impairment. Nonetheless, health-related quality of life (HRQoL) in patients with systemic sclerosis is often left behind in clinical practice and research. One of the reasons for this lack of evaluation is the current use of tools, such as the short form-36 (SF-36) questionnaire, that are complete but complicated to use in everyday routine. Other self-reported outcome measures such as the health assessment questionnaire (HAQ) are simple, but specifically designed for physical disability...
January 19, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/28102697/goal-intention-reminding-in-traumatic-brain-injury-a-feasibility-study-using-implementation-intentions-and-text-messaging
#19
Tessa Hart, Monica J Vaccaro
OBJECTIVE: To examine feasibility of participant-created implementation intentions, delivered as text message reminders, to enhance goal-related activity in persons with chronic, moderate/severe traumatic brain injury (TBI). DESIGN: Pilot randomized controlled trial on effects of 8 weeks receiving goal-related implementation intentions (GI) compared to control condition, educational review regarding goals (GR). PARTICIPANTS: Eight persons with moderate/severe TBI nearing discharge from intensive outpatient brain injury treatment...
January 19, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28102501/characteristics-of-social-support-among-teenage-optimal-age-and-advanced-age-women-in-canada-an-analysis-of-the-national-longitudinal-survey-of-children-and-youth
#20
Theresa H M Kim, Michael Rotondi, Jennifer Connolly, Hala Tamim
Background Social support is highly valued and beneficial for women, especially after childbirth. The objective was to examine the differences of social support reported among teen, optimal age, and advanced age women, and to identify the characteristics associated with social support separately for each age group. Methods This was a cross-sectional analysis of the National Longitudinal Survey of Children and Youth. Primiparous women with infants were grouped into: teen (15-19 years), optimal age (20-34 years), and advanced age (35 years and older)...
January 19, 2017: Maternal and Child Health Journal
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