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cognitive behavioral analysis

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https://www.readbyqxmd.com/read/29690837/neutralization-of-interleukin-1%C3%AE-following-diffuse-traumatic-brain-injury-in-the-mouse-attenuates-the-loss-of-mature-oligodendrocytes
#1
Johanna Flygt, Karsten Ruscher, Amanda Norberg, Anis Mir, Hermann Gram, Fredrik Clausen, Niklas Marklund
Traumatic brain injury (TBI) commonly results in injury to the components of the white matter tracts, causing post-injury cognitive deficits. The myelin-producing oligodendrocytes (OLs) are vulnerable to TBI although may plausibly be replaced by proliferating oligodendrocyte progenitor cells (OPCs). The cytokine interleukin-1β (IL-1β) is a key mediator of the complex inflammatory response, and when neutralized in experimental TBI behavioral outcome was improved. To evaluate the role of IL-1β on OL cell death and OPC proliferation, 116 adult male mice subjected to sham injury or the central fluid percussion injury (cFPI) model of traumatic axonal injury, were analyzed at 2, 7 and 14 days post-injury...
April 25, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29689045/two-year-impact-of-community-based-health-screening-and-parenting-groups-on-child-development-in-zambia-follow-up-to-a-cluster-randomized-controlled-trial
#2
Peter C Rockers, Arianna Zanolini, Bowen Banda, Mwaba Moono Chipili, Robert C Hughes, Davidson H Hamer, Günther Fink
BACKGROUND: Early childhood interventions have potential to offset the negative impact of early adversity. We evaluated the impact of a community-based parenting group intervention on child development in Zambia. METHODS AND FINDINGS: We conducted a non-masked cluster-randomized controlled trial in Southern Province, Zambia. Thirty clusters of villages were matched based on population density and distance from the nearest health center, and randomly assigned to intervention (15 clusters, 268 caregiver-child dyads) or control (15 clusters, 258 caregiver-child dyads)...
April 2018: PLoS Medicine
https://www.readbyqxmd.com/read/29687527/amygdala-real-time-fmri-neurofeedback-for-major-depressive-disorder-a-review
#3
Kymberly D Young, Vadim Zotev, Raquel Phillips, Masaya Misaki, Wayne C Drevets, Jerzy Bodurka
Advances in imaging technologies have allowed for the analysis of fMRI data in real-time (rtfMRI), leading to the development of neurofeedback (nf) training. This rtfMRI-nf training utilizes fMRI tomographic localization capacity to allow a person to see and regulate the localized hemodynamic signal from his or her own brain. In this review, we summarize the results of several studies that have developed and applied neurofeedback training to healthy and depressed individuals with the amygdala as the neurofeedback target and the goal to increase the hemodynamic response during positive autobiographical memory recall...
April 23, 2018: Psychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/29687240/simultaneous-assessment-of-cognitive-function-circadian-rhythm-and-spontaneous-activity-in-aging-mice
#4
Sreemathi Logan, Daniel Owen, Sixia Chen, Wei-Jen Chen, Zoltan Ungvari, Julie Farley, Anna Csiszar, Amanda Sharpe, Maarten Loos, Bastijn Koopmans, Arlan Richardson, William E Sonntag
Cognitive function declines substantially with age in both humans and animal models. In humans, this decline is associated with decreases in independence and quality of life. Although the methodology for analysis of cognitive function in human models is relatively well established, similar analyses in animal models have many technical issues (e.g., unintended experimenter bias, motivational issues, stress, and testing during the light phase of the light dark cycle) that limit interpretation of the results. These caveats, and others, potentially bias the interpretation of studies in rodents and prevent the application of current tests of learning and memory as part of an overall healthspan assessment in rodent models of aging...
April 24, 2018: GeroScience
https://www.readbyqxmd.com/read/29685868/development-of-a-healthy-lifestyle-mobile-app-for-overweight-pregnant-women-qualitative-study
#5
Ying Lau, Ling Jie Cheng, Claudia Chi, Cammy Tsai, Kai Wen Ong, Sarah Su Tin Ho-Lim, Wei Wang, Kian-Lee Tan
BACKGROUND: Mobile apps are becoming an increasingly ubiquitous platform for delivery of health behavior interventions among overweight and obese perinatal women. However, only a few methodological guidelines on integrating theory, evidence, and qualitative research for their designs are available. OBJECTIVE: The aim of this study was to develop a theory-based, evidence-driven, and user-centered healthy lifestyle app targeting overweight and obese multiethnic pregnant women...
April 23, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29685698/psychological-predictors-of-the-combined-adoption-of-physical-exercise-and-dietary-change-among-adults-with-hypercholesterolemia
#6
P Gomez, S Boesen-Mariani, E Bruckert
BACKGROUND: Although combined changes in eating habits and physical activity are pivotal to hypercholesterolemia management and the prevention of cardiovascular disease, little is known about the factors influencing the adoption of both behaviors by adults with hypercholesterolemia. The goal of this study was to identify psychological factors that predict a combined adoption of dietary modification and physical activity among adults with hypercholesterolemia. METHODS: We recruited a sample of 1100 adults with hypercholesterolemia (56...
April 20, 2018: Revue D'épidémiologie et de Santé Publique
https://www.readbyqxmd.com/read/29685366/identifying-quality-markers-from-shengmai-san-protects-against-transgenic-mouse-model-of-alzheimer-s-disease-using-chinmedomics-approach
#7
Ai-Hua Zhang, Jing-Bo Yu, Hui Sun, Ling Kong, Xiang-Qian Wang, Qing-Yu Zhang, Xi-Jun Wang
BACKGROUND: Shengmai San (SMS), a Chinese classic herbal formula, has been widely used for the treatment of Qi-Yin deficiency syndrome in Asia. Modern pharmacological studies have shown that SMS improves the cognitive function. However, the quality markers (Q-markers) for SMS still need further research. PURPOSE: Using chinmedocmics strategy to systematically evaluate the efficacy of SMS in the treatment of APPswe/PS1dE9 (APP/PS1) transgenic model of Alzheimer's disease (AD) and to discover the efficacy-related Q-markers...
April 3, 2018: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/29684643/neural-dynamics-of-breaking-continuous-flash-suppression
#8
Magdalena Del Río, Mark W Greenlee, Gregor Volberg
Sensory input to the human visual system often becomes accessible to cognition and overt report during processing. We investigated neural precursors of conscious vision using EEG recordings and the popular breaking continuous flash suppression (bCFS) paradigm. In this technique, a mask consisting of high-contrast dynamic patterns is presented to one eye, predominating over a target stimulus presented to the other eye. The time needed for the target stimulus to overcome the suppression is thought to reflect the transition from unconscious to conscious perception...
April 20, 2018: NeuroImage
https://www.readbyqxmd.com/read/29684403/white-matter-pathways-and-social-cognition
#9
REVIEW
Yin Wang, Athanasia Metoki, Kylie H Alm, Ingrid R Olson
There is a growing consensus that social cognition and behavior emerge from interactions across distributed regions of the "social brain". Researchers have traditionally focused their attention on functional response properties of these gray matter networks and neglected the vital role of white matter connections in establishing such networks and their functions. In this article, we conduct a comprehensive review of prior research on structural connectivity in social neuroscience and highlight the importance of this literature in clarifying brain mechanisms of social cognition...
April 20, 2018: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/29683081/self-blame-and-ptsd-following-sexual-assault-a-longitudinal-analysis
#10
Nora K Kline, Danielle S Berke, Charla A Rhodes, Maria M Steenkamp, Brett T Litz
Sexual assault is a prevalent trauma associated with high rates of posttraumatic stress disorder (PTSD). Social,cognitive theories posit that behavioral self-blame (i.e., attributing the cause of the assault to personal peri-event behavior) contributes to the etiology and maintenance of PTSD symptoms. Yet the direction of the association between self-blame and PTSD symptoms in the acute aftermath of sexual assault is unknown. This study evaluated temporal pathways between behavioral self-blame and PTSD symptom severity in an epidemiological sample of sexual assault survivors ( n = 126) assessed at four time points in the months immediately following the assault...
April 1, 2018: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29682852/novel-in-silico-multivariate-mapping-of-intrinsic-and-anticorrelated-connectivity-to-neurocognitive-functional-maps-supports-the-maturational-hypothesis-of-adhd
#11
Nina de Lacy, Ian Kodish, Srinivas Rachakonda, Vince D Calhoun
From childhood to adolescence, strengthened coupling in frontal, striatal and parieto-temporal regions associated with cognitive control, and increased anticorrelation between task-positive and task-negative circuits, subserve the reshaping of behavior. ADHD is a common condition peaking in adolescence and regressing in adulthood, with a wide variety of cognitive control deficits. Alternate hypotheses of ADHD emphasize lagging circuitry refinement versus categorical differences in network function. However, quantifying the individual circuit contributions to behavioral findings, and relative roles of maturational versus categorical effects, is challenging in vivo or in meta-analyses using task-based paradigms within the same pipeline, given the multiplicity of neurobehavioral functions implicated...
April 22, 2018: Human Brain Mapping
https://www.readbyqxmd.com/read/29682511/preferences-of-older-adults-and-their-families-for-meaningful-use-clinical-summaries
#12
Karen Colorafi, Robert A Greenes, Marc Kates
Background: This study assessed the perceptions of older adults regarding the plan of care (POC) contained in the clinical summary mandated by the Electronic Health Records (EHR) Incentive Program. Methods: A qualitative descriptive design was selected for this study. Older adults (≥65) with chronic cardiac diagnoses were invited to participate. The investigator shadowed the physician during the patient encounter, interviewed the patients following their encounter, and asked patients to complete standard health literacy and cognitive screening tools and the Patient Activation Measure...
2018: MHealth
https://www.readbyqxmd.com/read/29680773/changes-in-the-hippocampal-and-peripheral-phospholipid-profiles-are-associated-with-neurodegeneration-hallmarks-in-a-long-term-global-cerebral-ischemia-model-attenuation-by-linalool
#13
Angélica Maria Sabogal-Guáqueta, Rafael Posada-Duque, Natalie Charlotte Cortes, Julian D Arias-Londoño, Gloria Patricia Cardona-Gómez
Phospholipid alterations in the brain are associated with progressive neurodegeneration and cognitive impairment after acute and chronic injuries. Various types of treatments have been evaluated for their abilities to block the progression of the impairment, but effective treatments targeting long-term post-stroke alterations are not available. In this study, we analyzed changes in the central and peripheral phospholipid profiles in ischemic rats and determined whether a protective monoterpene, Linalool, could modify them...
April 19, 2018: Neuropharmacology
https://www.readbyqxmd.com/read/29680521/successful-performance-and-cardiovascular-markers-of-challenge-and-threat-a-meta-analysis
#14
REVIEW
Maciej Behnke, Lukasz D Kaczmarek
Cardiovascular responses to challenge and threat have been used extensively in psychophysiological research. In this meta-analysis, we scrutinized the body of evidence for the role of challenge and threat hemodynamic responses in predicting positive behavioral outcomes, i.e., performance quality. We accounted for cardiac output (CO), total peripheral resistance (TPR), and Challenge-Threat Index (CTI). With 17 articles covering 19 studies (total N = 1045), we observed that the literature might have been biased towards positive results...
April 19, 2018: International Journal of Psychophysiology
https://www.readbyqxmd.com/read/29679914/a-multi-site-proof-of-concept-investigation-of-computerized-approach-avoidance-training-in-adolescent-cannabis-users
#15
Joanna Jacobus, Charles T Taylor, Kevin M Gray, Lindsay R Meredith, Anna M Porter, Irene Li, Norma Castro, Lindsay M Squeglia
BACKGROUND: Few effective treatment options exist for cannabis-using youth. This pilot study aimed to test Approach-Avoidance Training to reduce cannabis use with non-treatment-seeking adolescents. METHODS: Eighty cannabis-using non-treatment-seeking adolescents (average age 19) were recruited from San Diego, California and Charleston, South Carolina, and randomized to complete either six sessions of Cannabis Approach-Avoidance Task Training (CAAT-training) designed to reduce automatic approach biases for cannabis cues or CAAT-sham training...
April 11, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29678563/pilot-randomized-trial-of-integrated-cognitive-behavioral-therapy-and-neuromuscular-training-for-juvenile-fibromyalgia-the-fit-teens-program
#16
Susmita Kashikar-Zuck, William R Black, Megan Pfeiffer, James Peugh, Sara E Williams, Tracy V Ting, Staci Thomas, Katie Kitchen, Gregory D Myer
Cognitive-behavioral therapy (CBT) improves coping and daily functioning in adolescents with juvenile fibromyalgia (JFM), but is less effective in reducing pain. This pilot trial evaluated the efficacy of a novel intervention (Fibromyalgia Integrative Training for Teens; FIT Teens) which integrates CBT with specialized neuromuscular exercise training to enhance the impact of treatment on reducing pain and disability. Forty adolescents with JFM (12-18 years) were randomized to CBT-only or FIT Teens. Treatment was conducted in group-based sessions over 8 weeks with assessments at baseline, post-treatment, and 3-month follow-up (primary endpoint)...
April 17, 2018: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/29678193/treating-prolonged-grief-disorder-with-prolonged-grief-specific-cognitive-behavioral-therapy-study-protocol-for-a-randomized-controlled-trial
#17
Rita Rosner, Eline Rimane, Anna Vogel, Jörn Rau, Maria Hagl
BACKGROUND: Prolonged grief disorder (PGD) has emerged as a well-defined and relatively common mental disorder that will be included in the upcoming revision of the International Classification of Diseases. Recent trials with grief-specific, mostly cognitive behavioral interventions for patients with a clinically relevant diagnosis of PGD showed large effect sizes. However, a small trial suggested that non-specific behavioral activation might suffice to improve PGD. So, more evidence for the relative efficacy of grief-specific treatments is needed, as is more research on the predictors of treatment success...
April 20, 2018: Trials
https://www.readbyqxmd.com/read/29677548/combination-of-curcumin-and-vagus-nerve-stimulation-attenuates-cerebral-ischemia-reperfusion-injury-induced-behavioral-deficits
#18
Jian Xu, Xinjuan Kong, Hong Xiu, Yihe Dou, Zeyu Wu, Peng Sun
AIM: Previous studies indicated that cerebral ischemia/reperfusion injury (CI/RI) could induce behavioral deficits. Single treatment of vagus nerve stimulation (VNS) or curcumin is reported to restore CI/RI-induced behavioral deficits. However, the synergic effect remains unclear. MATERIALS AND METHODS: Rats were divided into 6 groups: sham, CI/RI, VNS, CI/RI + VNS, VNS + curcumin and CI/RI + VNS + curcumin groups. Each group was further divided into three or four subgroups for further assessments...
April 17, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29677451/treatment-features-associated-with-youth-cognitive-behavioral-therapy-follow-up-effects-for-internalizing-disorders-a-meta-analysis
#19
Michael Sun, Leslie R Rith-Najarian, Timothy J Williamson, Bruce F Chorpita
Our aim was to investigate whether four treatment features (i.e., the inclusion of parental involvement, goal-setting strategies, maintenance/relapse prevention sessions, the addition of booster sessions) were associated with posttreatment and follow-up effect size of youth cognitive behavioral therapies (yCBTs) for anxiety, depression, posttraumatic stress disorder, and obsessive-compulsive disorder in age groups spanning young children to adolescents. We conducted a random-effects meta-analysis of 106 yCBTs tested in 76 randomized clinical trials from the PracticeWise Database to examine average effects of yCBTs posttreatment and at a later follow-up assessment...
April 20, 2018: Journal of Clinical Child and Adolescent Psychology
https://www.readbyqxmd.com/read/29676960/psychotherapy-targeting-depression-and-anxiety-for-use-in-palliative-care-a-meta-analysis
#20
Jessica J Fulton, Amie R Newins, Laura S Porter, Katherine Ramos
BACKGROUND: Research on the effectiveness of evidence-based practices in the treatment of depression and anxiety with palliative care populations is primarily limited to individuals having specific conditions such as cancer. OBJECTIVE: This meta-analysis examined the effect of psychotherapy on depression and anxiety among individuals with any condition appropriate for palliative care. METHODS: We searched PubMed, PsycINFO, Cochrane Library, and EMBASE databases until August 2017...
April 20, 2018: Journal of Palliative Medicine
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