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https://www.readbyqxmd.com/read/28736356/finite-element-analysis-of-influence-of-axial-position-of-center-of-rotation-of-a-cervical-total-disc-replacement-on-biomechanical-parameters-simulated-two-level-replacement-based-on-a-validated-model
#1
Yang Li, Zhenjun Zhang, Zhenhua Liao, Zhongjun Mo, Weiqiang Liu
Finite element (FE) models have been widely used to predict biomechanical parameters of the cervical spine. Previous studies investigated the influence of position of rotational centers (RCs) of prostheses on the cervical biomechanical parameters after one-level total disc replacement (TDR). The purpose of this study was to make a further step by exploring the effects of axial position of RCs of prostheses on the cervical biomechanics after 2-level TDR. A validated FE model of C3-C7 segments and 2 prostheses, including the RC located at the superior endplate (SE) and inferior endplate (IE), was developed...
July 20, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28735122/ventral-lumbar-synovial-cyst-causing-cauda-equina-compression-case-report-and-literature-review
#2
Anan Shtaya, Ahmed-Ramadan Sadek, Mark Walker, Ali Nader-Sepahi
BACKGROUND: Juxtafacet spinal cysts are cystic synovial lesions that are often indistinguishable clinically or radiologically and require histopathology analysis to confirm the diagnosis. Lumbar synovial cysts usually arising from the synovium of the facet joints. They have been described posterolateral or rarely in the posterior midline. However, we describe the first synovial cyst ventral to the dural sac. CASE DESCRIPTION: We report a lumbar 3-4 lesion causing cauda equina compression in a 57-year-old man who presented with 3 months history of low back pain and bilateral sciatica, intermittent urinary incontinence and erectile dysfunction...
July 19, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28728847/a-novel-role-for-bone-derived-cells-in-ankylosing-spondylitis-focus-on-il-23
#3
Sungsin Jo, Bon San Koo, Bitnara Lee, Eunji Kwon, Young Lim Lee, Heekyoung Chung, Il-Hoon Sung, Ye-Soo Park, Tae-Hwan Kim
The main aim of this study are to explore the role of bone-derived cells (BdCs) in ankylosing spondylitis (AS) and determine the underlying molecular mechanisms of IL-23 production. Primary BdCs were isolated from diced bone of facet joints obtained during surgery from seven AS patients and seven disease control (Ct) patients. Osteoblastic activity of BdCs was assessed by measuring their alkaline phosphatase activity and by alizarin red staining. Osteoblast and endoplasmic reticulum (ER) stress-related genes were assessed by quantitative PCR, immunoblotting, immunofluorescence, and immunohistochemistry...
July 17, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28728587/minimally-invasive-unilateral-pedicle-screws-and-a-translaminar-facet-screw-fixation-and-interbody-fusion-for-treatment-of-single-segment-lower-lumbar-vertebral-disease-surgical-technique-and-preliminary-clinical-results
#4
Peng Huang, Yiguo Wang, Jiao Xu, Bo Xiao, Jianheng Liu, Luyang Che, Keya Mao
BACKGROUND: Conventional open transforaminal lumbar interbody fusion (TLIF) using unilateral pedicle screws and a translaminar facet screw has been performed for many years with good results. The outcomes of minimally invasive TLIF (MIS TLIF) are similar to the good outcomes of open TLIF, with the additional benefits of reducing iatrogenic injury, shortening hospital stays, and reducing the recovery duration. Instead of using small cuts on both sides, we performed MIS TLIF through a single cut using unilateral pedicle screws and a translaminar facet screw...
July 20, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28728206/-subaxial-cervical-spine-injuries-treatment-recommendations-of-the-german-orthopedic-and-trauma-society
#5
Philipp Schleicher, Matti Scholz, Frank Kandziora, Andreas Badke, Florian Hans Brakopp, Helmut Klaus Friedrich Ekkerlein, Erol Gercek, Rene Hartensuer, Philipp Hartung, Jan-Sven Gilbert Jarvers, Philipp Kobbe, Stefan Matschke, Robert Morrison, Christian W Müller, Miguel Pishnamaz, Maximilian Reinhold, Klaus John Schnake, Gregor Schmeiser, Gregor Stein, Bernhard Ullrich, Thomas Weiß, Volker Zimmermann
In a consensus process during four sessions in 2016, the working group "lower cervical spine" of the German Society for Orthopedic and Trauma Surgery (DGOU), formulated "Therapeutic Recommendations for the Lower Cervical Spine", taking into consideration the current literature. Therapeutic goals are a permanently stable, painless cervical spine and the protection against secondary neurologic damage while retaining the greatest possible amount of motion and spinal profile. Due to its ease of use and its proven good reliability, the AOSpine classification for subaxial cervical injuries should be used...
July 20, 2017: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/28723774/relationship-between-first-dorsal-sacral-foramen-and-lumbar-facet-joint-connecting-line-in-south-korea-populations-retrospective-study
#6
Young Deog Cha, Jae Kyu Choi, Chun Woo Yang, Hyun Kyoung Lim, Gyoung A Heo, Byung-Gun Kim
The first sacral nerve root block (S1 nerve root block) is a practical procedure for patients with radiating lower back pain. In general, S1 nerve root block is performed under x-ray fluoroscopy. It is necessary to adjust the position of the patient and angle of fluoroscopy to properly visualize the first dorsal sacral foramen (dorsal S1 foramen). The purpose of this study was to analyze the location of dorsal S1 foramen and lumbar facet joint in S1 nerve root block.A total of 388 patients undergoing x-ray fluoroscopy-guided S1 nerve root block in the prone position were examined...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28723772/anatomic-investigation-of-lumbar-transforaminal-fenestration-approach-and-its-clinical-application-in-far-lateral-disc-herniation
#7
Baoshan Xu, Haiwei Xu, Jean Destandau, Xinlong Ma, Jian He, Qun Xia, Ning Ji, Qiang Yang, Yue Liu, Hongfeng Jiang
Treating lumbar disease at the intervertebal foramina is controversial because we lack an approach providing sufficient exposure and preserving spinal stability. The primary objective of this study was to investigate the feasibility of the transforaminal fenestration (TFF) approach for treating lumbar disease involving the intervertebal foramina.In the anatomic study of 30 adult cadaveric lumbar spine specimens, the TFF approach was used from L1 to S1. The scope of resection was measured manually and on 3D CT images...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28723737/how-to-choose-when-implants-of-adjacent-height-both-fit-the-disc-space-properly-in-single-level-cervical-artificial-disc-replacement
#8
Xin Rong, Jigang Lou, Huibo Li, Yang Meng, Hao Liu
In cervical artificial disc replacement (C-ADR), sometimes we encountered with such cases that implants of adjacent height both fit the target disc space properly. No study was available discussing the choice of implant height and the clinical outcomes under such circumstance. The purpose of this study was to evaluate the impact of different implant heights on the clinical outcomes and radiographic results when the implants of adjacent height both fit the disc space properly. This retrospective study included 34 patients underwent single-level C-ADR at the C5-C6 level at our institution...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28722281/collagen-organization-regulates-stretch-initiated-pain-related-neuronal-signals-in-vitro-implications-for-structure-function-relationships-in-innervated-ligaments
#9
Sijia Zhang, Sagar Singh, Beth A Winkelstein
Injury to the spinal facet capsule, an innervated ligament with heterogeneous collagen organization, produces pain. Although mechanical facet joint trauma activates embedded afferents, it is unclear if, and how, the varied extracellular microstructure of its ligament affects sensory transduction for pain from mechanical inputs. To investigate the effects of macroscopic deformations on afferents in collagen matrices with different organizations, an in vitro neuron-collagen construct (NCC) model was used. NCCs with either randomly organized or parallel aligned collagen fibers were used to mimic the varied microstructure in the facet capsular ligament...
July 19, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28719806/effect-of-cage-design-supplemental-posterior-instrumentation-and-approach-on-primary-stability-of-a-lumbar-interbody-fusion-a-biomechanical-in-vitro-study
#10
Werner Schmoelz, Sabrina Sandriesser, Oded Loebl, Marlies Bauer, Dietmar Krappinger
BACKGROUND: There are various techniques and approaches for lumbar interbody fusion differing in access, cage type and type of supplemental posterior instrumentation. While a transforaminal access usually includes a hemifacetectomy, the facet joint can be preserved with a more lateral extraforaminal access. The supplemental posterior instrumentation required for both fusion techniques is still debated. The purpose of the present study was to compare primary stability of the two accesses for two different cage types with none, unilateral and bilateral supplemental posterior instrumentation...
July 8, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28719446/tophaceous-gout-of-the-lumbar-spine-mimicking-malignancy-on-fdg-pet-ct
#11
Qian Zhao, Aisheng Dong, Yushu Bai, Yang Wang, Changjing Zuo
A 46-year-old man with over a 10-year history of gout complained of progressive bilateral buttock pain with numbness of legs for 4 months. Serum uric acid level was elevated. Lumbar radiographs showed decreased density of the bilateral L4-L5 facet joints. CT showed lytic lesions of the facet joints with hyperdense periarticular lesions. Enhanced MRI showed marked enhancement of these lesions. FDG PET/CT showed avid FDG uptake of the bony and periarticular lesions with SUVmax of 16.8. A decompressive posterior lumbar laminectomy with periarticular lesion resection was performed...
July 17, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28714535/neandertal-talus-bones-from-el-sidr%C3%A3-n-site-asturias-spain-a-3d-geometric-morphometrics-analysis
#12
Antonio Rosas, Anabel Ferrando, Markus Bastir, Antonio García-Tabernero, Almudena Estalrrich, Rosa Huguet, Daniel García-Martínez, Juan Francisco Pastor, Marco de la Rasilla
OBJECTIVES: The El Sidrón tali sample is assessed in an evolutionary framework. We aim to explore the relationship between Neandertal talus morphology and body size/shape. We test the hypothesis 1: talar Neandertal traits are influenced by body size, and the hypothesis 2: shape variables independent of body size correspond to inherited primitive features. MATERIALS AND METHODS: We quantify 35 landmarks through 3D geometric morphometrics techniques to describe H...
July 17, 2017: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/28713612/in-vivo-magnetic-resonance-imaging-morphometry-of-the-patella-bone-in-south-indian-population
#13
Reshma Muhamed, Vasudha V Saralaya, B V Murlimanju, Ganesh Kumar Chettiar
Racial differences exist in the dimensions of structures and the commercially available prostheses are designed based on the Caucasians. In this context, the goal of the present investigation was to determine the gender wise measurements of patella bone in South Indians. The present study included axial magnetic resonance images of the knee joint from 140 South Indian adults (70 males, 70 females; aged between 20-70 years). The angle, width, thickness, lateral facet width, facet thickness, ratio of the lateral facet, the relative thickness and ratio of facet thickness were measured in the patella by using the digital ruler...
June 2017: Anatomy & Cell Biology
https://www.readbyqxmd.com/read/28713051/3d-visualization-and-pathological-characteristics-of-cartilage-and-subchondral-bone-changes-in-the-lumbar-facet-joint-of-an-ovariectomized-mouse-model
#14
Yong Cao, Shuangfei Ni, Tianding Wu, Chunyue Duan, Shenghui Liao, Jianzhong Hu
BACKGROUD CONTEXT: Low back pain (LBP) is more prevalent among postmenopausal women than men. Ovariectomy (OVX) is an established animal model that mimics the estrogen deficiency of postmenopausal women. Little is known about the morphological properties of cartilage and subchondral bone changes in the lumbar facet joint (LFJ) of an OVX mouse model. PURPOSE: The purpose of this study is to characterize the morphological change of cartilage and subchondral bone in LFJ of an OVX mouse model...
July 13, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28713050/the-biomechanical-impact-of-the-facet-tropism-on-the-intervertebral-disc-and-facet-joints-in-the-cervical-spine
#15
Xin Rong, Beiyu Wang, Chen Ding, Yuxiao Deng, Hua Chen, Yang Meng, Weijie Yan, Hao Liu
BACKGROUND CONTEXT: The facet tropism is defined as the angular difference between the left and right facet orientation. The facet tropism was suggested to be associated with the disc degeneration and facet degeneration in the lumbar spine. However, little is known about the relationship between the facet tropism and pathological changes in the cervical spine and the mechanism behind. PURPOSE: This study was conducted to investigate the biomechanical impact of the facet tropism on the intervertebral disc and facet joints...
July 13, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28711584/biomarkers-reflect-differences-in-osteoarthritis-phenotypes-of-the-lumbar-spine-the-johnston-county-osteoarthritis-project
#16
Adam P Goode, Amanda E Nelson, Virginia B Kraus, Jordan B Renner, Joanne M Jordan
OBJECTIVE: To determine differences in biomarker levels between radiographic phenotypes of facet joint osteoarthritis (FOA) only, spine OA only ((disc space narrowing (DSN) and vertebral osteophytes (OST)) or the combination of FOA and spine OA. DESIGN: A cross-sectional analysis of data from 555 participants in the Johnston County Osteoarthritis Project was performed. Lumbar spine levels were graded by severity (OST and DSN) and presence (FOA) of degeneration. Biomarkers included hyaluronan (HA) and type II collagen (CTX-II)...
July 12, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28708547/multimodal-fusion-with-reference-searching-for-joint-neuromarkers-of-working-memory-deficits-in-schizophrenia
#17
Shile Qi, Vince D Calhoun, Theo G M van Erp, Juan Bustillo, Eswar Damaraju, Jessica A Turner, Yuhui Du, Jian Yang, Jiayu Chen, Qingbao Yu, Daniel H Mathalon, Judith M Ford, James Voyvodic, Bryon A Mueller, Aysenil Belger, Sarah McEwen, Steven G Potkin, Adrian Preda, Tianzi Jiang, Jing Sui
By exploiting cross-information among multiple imaging data, multimodal fusion has often been used to better understand brain diseases. However, most current fusion approaches are blind, without adopting any prior information. There is increasing interest to uncover the neurocognitive mapping of specific clinical measurements on enriched brain imaging data; hence, a supervised, goal-directed model that employs prior information as a reference to guide multimodal data fusion is much needed and becomes a natural option...
July 11, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28707347/interspecific-variation-in-the-tetradactyl-manus-of-modern-tapirs-perissodactyla-tapirus-exposed-using-geometric-morphometrics
#18
Jamie A MacLaren, Sandra Nauwelaerts
The distal forelimb (autopodium) of quadrupedal mammals is a key morphological unit involved in locomotion, body support, and interaction with the substrate. The manus of the tapir (Perissodactyla: Tapirus) is unique within modern perissodactyls, as it retains the plesiomorphic tetradactyl (four-toed) condition also exhibited by basal equids and rhinoceroses. Tapirs are known to exhibit anatomical mesaxonic symmetry in the manus, although interspecific differences and biomechanical mesaxony have yet to be rigorously tested...
July 13, 2017: Journal of Morphology
https://www.readbyqxmd.com/read/28707222/considering-the-inferior-surface-area-of-lower-lumbar-vertebrae-determining-weight-transmission-pattern-at-the-lumbosacral-junction
#19
Uchenna Kenneth Ezemagu, Chike P Anibeze, Chinedu F Akpuaka
The biomechanical function of the lumbosacral junction (LSJ) is obscure, but its medical significance is not, as it is the most common site of low back pain. In this study, we analyzed the difference between the mean values of the surface areas of the inferior body and total inferior facet areas of the fourth and fifth lumbar vertebrae. We aimed to define the function of the LSJ during weight transmission and clarify its mechanical significance. Vertebral columns of 45 adult male human cadavers from five anatomy departments in Nigeria were cut at the L3-L4 intervertebral disc and macerated...
July 13, 2017: Anatomical Science International
https://www.readbyqxmd.com/read/28704245/inciting-events-associated-with-lumbar-facet-joint-pain
#20
Charles A Odonkor, Yian Chen, Peju Adekoya, Bryan J Marascalchi, Hira Chaudhry-Richter, Teresa Tang, Christopher Abruzzese, Berklee K Cohen, Steven P Cohen
BACKGROUND: Low back pain is the leading cause of years lost to disability with approximately 15%-25% of the chronic back pain population suffering from lumbar facet arthropathy. No large-scale study has sought to systematically identify inciting events for lumbar facet arthropathy. The aim of this study is to quantify the proportion of individuals with lumbar facetogenic pain who report a specific precipitating event(s) and to determine if there is a correlation between these events and treatment outcome...
July 10, 2017: Anesthesia and Analgesia
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