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https://www.readbyqxmd.com/read/28076822/an-in-vitro-analysis-of-the-size-and-shape-of-cryolesions-for-facet-joint-denervation
#1
T Wolter, Y Bozhkov, S M Knoeller
OBJECTIVES: Lumbar facet joint syndrome (LFJS) is the cause of lower back pain in 15-54% of the patients. Clinical studies of cryotherapy for LFJS have reported promising outcomes. However, few studies have focused on the technical aspects of cryoneurolysis for LFJS. The aim of the study was to determine the size and shape of cryolesions in vitro and to determine how they are affected by the duration of freezing, size of the cryoprobe and distance and angulation to an osseous boundary layer...
January 4, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28056123/the-interface-of-mechanics-and-nociception-in-joint-pathophysiology-insights-from-the-facet-temporomandibular-joints
#2
Megan M Sperry, Meagan E Ita, Sonia Kartha, Sijia Zhang, Ya-Hsin Yu, Beth Winkelstein
Chronic joint pain is a widespread problem that frequently occurs with aging and trauma. Pain occurs most often in synovial joints, the body's load bearing joints. The mechanical and molecular mechanisms contributing to synovial joint pain are reviewed using two examples, the cervical spinal facet joints and temporomandibular joint. Although much work has focused on the macroscale mechanics of joints in health and disease, the combined influence of tissue mechanics, molecular processes, and nociception in joint pain has only recently become a focus...
January 5, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28042726/hybrid-cervical-disc-arthroplasty
#3
Tsung-Hsi Tu, Jau-Ching Wu, Henrich Cheng, Praveen V Mummaneni
For patients with multilevel cervical stenosis at nonadjacent segments, one of the traditional approaches has included a multilevel fusion of the abnormal segments as well as the intervening normal segment. In this video we demonstrate an alternative treatment plan with tailored use of a combination of anterior cervical discectomy and fusion (ACDF) and cervical disc arthroplasty (CDA) with an intervening skipped level. The authors present the case of a 72-year-old woman with myeloradiculopathy and a large disc herniation with facet joint degeneration at C3-4 and bulging disc at C5-6...
January 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28040243/radiographic-damage-and-progression-of-the-cervical-spine-in-ankylosing-spondylitis-patients-treated-with-tnf-%C3%AE-inhibitors-facet-joints-vs-vertebral-bodies
#4
Fiona Maas, Anneke Spoorenberg, Elisabeth Brouwer, Eveline van der Veer, Hendrika Bootsma, Reinhard Bos, Freke R Wink, Suzanne Arends
OBJECTIVES: To investigate radiographic damage and 4-year progression of the cervical facet joints in a prospective observational cohort of AS patients treated with TNF-α inhibitors, to compare this with damage and progression of the cervical vertebral bodies, and to study the relation with patient characteristics and clinical outcome. METHODS: Patients from the Groningen Leeuwarden AS (GLAS) cohort starting TNF-α inhibitors with baseline and 4-year radiographs were included...
November 9, 2016: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/28032224/asymmetric-c7-pedicle-subtraction-osteotomy-for-correction-of-rigid-cervical-coronal-imbalance-secondary-to-post-traumatic-heterotopic-ossification-a-case-report-description-of-a-novel-surgical-technique-and-literature-review
#5
Alexander A Theologis, Kate D Bellevue, Erion Qamirani, Christopher P Ames, Vedat Deviren
PURPOSE: Deformities of the cervical spine are uncommon in the coronal plane. In this report, a unique case of a 31-year-old male with a fixed, 30° left coronal deformity due to heterotopic ossification 3 years status post poly-trauma was treated with an asymmetric C7 pedicle subtraction osteotomy (PSO). METHODS: Case report. RESULTS: Pre-operatively, the patient had a fixed 45-degree left tilt of his neck and radiographs demonstrated a rigid 30° scoliosis, 7 cm coronal imbalance, and 4 cm negative sagittal balance, diffuse bridging bone between the spinous processes and the facet joints of C5 to T1 bilaterally...
December 28, 2016: European Spine Journal
https://www.readbyqxmd.com/read/28027083/reply-to-commentary-on-comparison-of-clinical-and-radiographic-outcomes-in-patients-receiving-transforaminal-lumbar-interbody-fusion-with-removal-of-unilateral-or-bilateral-facet-joints
#6
https://www.readbyqxmd.com/read/28025352/chronic-whiplash-associated-disorders-wad-responses-to-nerve-blocks-of-cervical-zygapophyseal-joints
#7
Mats Persson, Jan Sörensen, Björn Gerdle
OBJECTIVE: This study explores the prevalence of facet joint pain in chronic Whiplash Associated Disorder (WAD). DESIGN: Forty-seven patients with chronic WAD were scheduled for medial branch blocks of the cervical spine. METHODS: The patient's localization of the pain together with established pain maps guided to the first level of zygapophyseal joint to be tested. The joint was anesthetized by injecting bupivacaine (0.5 ml; 5 mg/ml) to the medial branches of the cervical dorsal rami above and below the joint...
December 2016: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28012693/tumoral-calcinosis-of-the-cervical-spine-in-a-dialysis-patient-case-report-and-review-of-the-literature
#8
Krzysztof Zapałowicz, Bartłomiej Stasiów, Monika Ciupińska-Kajor, Wojciech Piwowarski
The authors present a case of tumoral calcinosis (TC) in a patient with chronic renal insufficiency. The clinical course, imaging features and microscopic findings are detailed. A 60-year-old woman with a 4-year history of hemodialysis presented with a painful mass in the right posterior cervical triangle. The neuroimaging revealed polycystic mass bulging from the C3-C5 facet joints and lamina on the right. The majority of cystic mass was excised and microscopic features of the specimen were consistent with TC...
December 14, 2016: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/28012080/three-dimensional-micro-computed-tomography-analysis-for-spinal-instability-after-lumbar-facetectomy-in-the-rat
#9
Daisuke Fukui, Mamoru Kawakami, Kevin Cheng, Koichiro Murata, Keianne Yamada, Rinoka Sato, Munehito Yoshida, Hiroshi Yamada, Nozomu Inoue, Koichi Masuda
PURPOSE: Intervertebral disc degeneration is thought to contribute to low back pain. However, the pathophysiological mechanisms remain controversial. In a previous study, we developed an animal model that showed delayed gait disturbance after lumbar facetectomy in the rat. We believe that this gait disturbance was caused by low back pain, although the mechanisms of this gait abnormality remain unknown. The purpose of this study was to evaluate structural changes of the lumbar spine after facetectomy in the rat utilizing three-dimensional micro-computed tomography (3DμCT) compared to histology...
December 23, 2016: European Spine Journal
https://www.readbyqxmd.com/read/28010945/impact-of-material-and-morphological-parameters-on-the-mechanical-response-of-the-lumbar-spine-a-finite-element-sensitivity-study
#10
Thomas Zander, Marcel Dreischarf, Anne-Katrin Timm, Wolfgang W Baumann, Hendrik Schmidt
Finite element models are frequently used to study lumbar spinal biomechanics. Deterministic models are used to reflect a certain configuration, including the means of geometrical and material properties, while probabilistic models account for the inherent variability in the population. Because model parameters are generally uncertain, their predictive power is frequently questioned. In the present study, we determined the sensitivities of spinal forces and motions to material parameters of intervertebral discs, vertebrae, and ligaments and to lumbar morphology...
December 16, 2016: Journal of Biomechanics
https://www.readbyqxmd.com/read/28005935/a-biomechanical-stability-study-of-extraforaminal-lumbar-interbody-fusion-on-the-cadaveric-lumbar-spine-specimens
#11
Song Guo, Cheng Zeng, Meijun Yan, Yingchao Han, Dongdong Xia, Guixin Sun, Lijun Li, Mingjie Yang, Jun Tan
BACKGROUND: Transforaminal lumbar interbody fusion (TLIF) is an effective surgery for lumbar degenerative disease. However, this fusion technique requires resection of inferior facet joint to provide access for superior facet joint resection, which results in reduced lumbar spinal stability and unnecessary trauma. We have previously developed extraforaminal lumbar interbody fusion (ELIF) that can avoid back muscle injury with direct nerve root decompression. This study aims to show that ELIF enhances lumbar spinal stability in comparison to TLIF by comparing lumbar spinal stability of L4-L5 range of motion (ROM) on 12 cadaveric spine specimens after performing TLIF or ELIF...
2016: PloS One
https://www.readbyqxmd.com/read/28003166/analysis-of-the-fusion-and-graft-resorption-rates-as-measured-by-ct-1-year-after-posterior-cervical-fusion-using-a-cervical-pedicle-screw
#12
Jae Koo Lee, Sang Ku Jung, Young-Seok Lee, Sang Ryong Jeon, Sung Woo Roh, Seung Chul Rhim, Jin Hoon Park
BACKGROUND: We previously showed that cervical pedicle screw placement (CPS) is safe even with the freehand technique. The posterolateral fusion rate 1 year after CPS, as measured by computed tomography (CT), is reported here. The graft resorption rates when different graft materials were used were also analyzed. METHODS: Between 2012- 2015, 93 patients underwent posterior cervical fusion surgery with the CPS from C2 to C7. Of these, 56 patients consented to CT scans immediately and 1 year after surgery...
December 18, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27994840/intraspinal-lumbar-juxtaarticular-cyst-treatment-through-ct-guided-percutaneus-induced-rupture-results-in-a-favorable-patient-outcome
#13
Adisa Kursumovic, Richard Bostelmann, Maria Gollwitzer, Stefan Rath, Hans Jakob Steiger, Athanasios K Petridis
Juxta-articular cysts are synovial cysts originating from the facet joints or the flava ligaments. If they grow intra-spinally they can compress nervous structures and cause a variety of symptoms. Micro-neurosurgery is usually the treatment of choice. Alternatively to surgical treatment the cyst can be approached and treated with a CT guided percutaneous injection inducing rupture. After fulfilling strict selection criteria twenty patients (25% of all treated lumbar synovial cyst patients), were treated minimally invasive by this method from 2010-2016...
October 24, 2016: Clinics and Practice
https://www.readbyqxmd.com/read/27994791/analysis-of-the-relationship-between-ligamentum-flavum-thickening-and-lumbar-segmental-instability-disc-degeneration-and-facet-joint-osteoarthritis-in-lumbar-spinal-stenosis
#14
Toyomi Yoshiiwa, Masashi Miyazaki, Naoki Notani, Toshinobu Ishihara, Masanori Kawano, Hiroshi Tsumura
STUDY DESIGN: Cross-sectional study. PURPOSE: To investigate the relationship between ligamentum flavum (LF) thickening and lumbar segmental instability and disc degeneration and facet joint osteoarthritis. OVERVIEW OF LITERATURE: Posterior spinal structures, including LF thickness, play a major role in lumbar spinal canal stenosis pathogenesis. The cause of LF thickening is multifactorial and includes activity level, age, and mechanical stress...
December 2016: Asian Spine Journal
https://www.readbyqxmd.com/read/27993739/septic-arthritis-of-an-atlantoaxial-facet-joint-with-normal-inflammatory-markers-case-report-and-literature-review
#15
Gokhan Kuyumcu, Claus S Simpfendorfer, Maja Babic, Iain H Kalfas, Lucileia Teixeira-Johnson, Carl S Winalski
BACKGROUND: Septic arthritis of the atlantoaxial facet joint is extremely rare. Contiguous spread to the median atlantoaxial joints with subsequent dens erosion can lead to atlantoaxial instability. Misleading normal inflammatory markers can result in delayed diagnosis and catastrophic consequences. CASE DESCRIPTION: A 56-year-old man presented with right-sided neck pain that had lasted for 2 days. He did not have fever or chills, and his serum C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) were normal...
December 16, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27989339/anatomic-description-of-the-naviculocuneiform-articulation
#16
Kevin Renner, Jeffrey E McAlister, Melissa M Galli, Christopher F Hyer
The naviculocuneiform articulation is composed of the navicular proximally and the 3 cuneiforms distally. It is not uncommon to perform surgical interventions at this joint for multiple pathologic foot etiologies. To date, no detailed anatomic measurement is available for each cuneiform articulation on the navicular. The purpose of the present study was to present an anatomic description of this complex joint to aid in better surgical understanding and improve surgical outcomes. Ten fresh, frozen, and thawed below-the-knee cadaveric specimens were used for anatomic dissection of the navicular and associated cuneiforms...
January 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/27989008/a-prospective-study-comparing-platelet-rich-plasma-and-la-corticosteroid-in-intra-articular-injection-for-the-treatment-of-lumbar-facet-joint-syndrome
#17
Jiuping Wu, Jingjing Zhou, Chibing Liu, Jun Zhang, Wei Xiong, Yang Lv, Rui Liu, Ruiqiang Wang, Zhenwu Du, Zhang Guizhen, Qinyi Liu
OBJECTIVES: To compare the effectiveness and safety between autologous platelet-rich plasma (PRP) and LA/corticosteroid in intra-articular injection for the treatment of lumbar facet joint syndrome. METHODS: Forty-six eligible patients with lumbar facet joint syndrome were randomized into group A (intra-articular injection with PRP) and group B (intra-articular injection with LA/corticosteroid). The following contents were evaluated: pain visual analog scale (VAS) at rest and during flexion, and the Roland-Morris Disability Questionnaire (RMQ), Oswestry Disability Index (ODI), and modified MacNab criteria for pain relief and applications of post-treatment drugs...
December 18, 2016: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/27977444/outcome-of-decompression-alone-for-foraminal-extraforaminal-entrapment-of-l5-nerve-root-through-wiltse-paraspinal-approach
#18
Kyung-Chul Choi, Jin-Sung Kim, Dong Chan Lee, Choon-Keun Park
STUDY DESIGN: Retrospective analysis. OBJECTIVE OF THE STUDY: The objective of the study was to present the surgical outcome and analyze the prognostic factors for postoperative leg pain after posterior decompression alone for foraminal/extraforaminal L5 entrapment at L5-S1 segment (LSS). SUMMARY OF BACKGROUND DATA: Disk extrusion, hypertrophy of facet joint, osteophyte of vertebral body, thickened lumbosacral ligament, and collapsed disk lead to form the lumbosacral tunnel which compresses the L5 exiting nerve root...
December 13, 2016: Clinical Spine Surgery
https://www.readbyqxmd.com/read/27965578/computational-models-of-reactive-oxygen-species-as-metabolic-byproducts-and-signal-transduction-modulators
#19
REVIEW
Elizabeth J Pereira, Christian M Smolko, Kevin A Janes
Reactive oxygen species (ROS) are widely involved in intracellular signaling and human pathologies, but their precise roles have been difficult to enumerate and integrate holistically. The context- and dose-dependent intracellular effects of ROS can lead to contradictory experimental results and confounded interpretations. For example, lower levels of ROS promote cell signaling and proliferation, whereas abundant ROS cause overwhelming damage to biomolecules and cellular apoptosis or senescence. These complexities raise the question of whether the many facets of ROS biology can be joined under a common mechanistic framework using computational modeling...
2016: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/27951615/endoscopic-management-of-spinal-intradural-extramedullary-tumors
#20
Vijay Singh Parihar, Nishtha Yadav, Yad Ram Yadav, Shailendra Ratre, Jitin Bajaj, Yatin Kher
Introduction Posterior midline laminectomy is associated with risks of postoperative instability, spinal deformity, extensive bilateral subperiosteal muscle stripping, partial or total facetectomy especially in foraminal tumor extension, increased cerebrospinal fluid leakage, and wound infection. Minimally invasive approaches with the help of a microscope or endoscope using hemilaminectomy have been found to be safe and effective. We report our initial experience of 18 patients using the endoscopic technique...
December 12, 2016: Journal of Neurological Surgery. Part A, Central European Neurosurgery
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