keyword
https://read.qxmd.com/read/38704519/identification-of-key-ernas-for-intervertebral-disc-degeneration-by-integrated-multinomial-bioinformatics-analysis
#1
JOURNAL ARTICLE
Yongai Li, Runzhi Huang, Jianxin Ye, Xiaying Han, Tong Meng, Dianwen Song, Huabin Yin
BACKGROUND: Intervertebral disc degeneration (IVDD) is a common degenerative condition leading to abnormal stress distribution under load, causing intervertebral stenosis, facet joint degeneration, and foraminal stenosis. Very little is known about the molecular mechanism of eRNAs in IVDD. METHODS: Gene expression profiles of 38 annulus disc samples composed of 27 less degenerated discs (LDs) and 11 more degenerated discs (MDs) were retrieved from the GEO database...
May 4, 2024: BMC Musculoskeletal Disorders
https://read.qxmd.com/read/38702827/osteoarthritis-of-zygapophysial-joints-as-a-cause-of-back-pain-and-neck-pain-a-scoping-review
#2
JOURNAL ARTICLE
Nikolai Bogduk, John MacVicar
BACKGROUND: Zygapophysial joints (Z joints) can be a source of back pain and of neck pain, but the cause of pain is not known. Some authors attribute the pain to osteoarthritis but without citing evidence. OBJECTIVES: The present review was undertaken to determine if there was sufficient evidence of association between spinal pain and osteoarthritis of Z joints to justify osteoarthritis being held to be the cause of pain. The null hypothesis was that osteoarthritis of Z joints does not cause back pain or neck pain...
May 3, 2024: Pain Medicine
https://read.qxmd.com/read/38691781/effectiveness-of-bruxism-treatment-in-young-adults
#3
JOURNAL ARTICLE
Oksana V Klitynska, Yurii M Martyts, Viacheslav R Gurando, Nataliya V Layoch
OBJECTIVE: Aim: This study aimed to assess the effectiveness of the developed algorithm for treatment and prevention measures aimed at eliminating clinical manifestations of bruxism in young people. PATIENTS AND METHODS: Materials and Methods: A cohort of 377 individuals aged 25 to 44 years underwent examination. Based on identified etiological factors, three distinct groups were delineated. Treatment and preventive strategies were then implemented and evaluated...
2024: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://read.qxmd.com/read/38679435/subtalar-osteochondral-lesions-diagnosis-indications-and-prognosis
#4
REVIEW
Allison L Boden, Jonathan Kaplan, Amiethab Aiyer
Although most commonly found in the knee, elbow, and talar dome, osteochondral lesions can also be found in the subtalar joint and can occur due to either high or low energy trauma. Diagnosis of these lesions in the subtalar joint is typically confirmed with advanced imaging such as computerized tomography and MRI. Although there are a few published case reports, there is otherwise very limited literature on the prevalence, treatment options, prognosis, or outcomes for patients with osteochondral lesions of the subtalar joint, and thus further research is required in this area...
June 2024: Foot and Ankle Clinics
https://read.qxmd.com/read/38679372/percutaneous-endoscopic-suprapedicular-decompression-in-the-treatment-of-down-migrated-lumbar-disc-herniation
#5
JOURNAL ARTICLE
Shiliang Li, Liangyu Zhong, Shijia Li, Lanxiang Du
[OBJECTIVE]: This study aimed to investigate the clinical efficacy of percutaneous endoscopic suprapedicular decompression in treatment of down-migrated lumbar disc herniation. [METHODS]: The clinical data of 43 patients with down-migrated lumbar disc herniation treated with endoscopic surgery at our hospital between January 2022 and January 2023 were retrospectively analysed. Twenty-two and 21 patients underwent percutaneous endoscopic decompression using the suprapedicular and TESSYS approaches, respectively...
April 26, 2024: World Neurosurgery
https://read.qxmd.com/read/38668721/exploring-the-influence-of-facet-orientation-and-tropism-on-neutral-zone-properties
#6
JOURNAL ARTICLE
Rory M Trevorrow, Jackie D Zehr, Jeff M Barrett, Jack P Callaghan, Kayla Fewster
Lumbar spine pathologies have been linked independently to both neutral zone (NZ) properties and facet joint anatomical characteristics; however, the effect of facet joint orientation (FO) and tropism (FT) on NZ properties remains unclear. The aim of the present study was to investigate how axial plane FO and FT relate to NZ range and stiffness in the human lumbar spine and porcine cervical spine. Seven human lumbar functional spine units (FSUs) and 94 porcine cervical FSUs were examined. FO and FT were measured, and in-vitro mechanical testing was used to determine anterior-posterior (AP) and flexion-extension (FE) NZ range and stiffness...
April 26, 2024: Journal of Biomechanical Engineering
https://read.qxmd.com/read/38664803/does-the-coronoid-fracture-in-terrible-triad-injury-always-need-to-be-fixed
#7
JOURNAL ARTICLE
Yeong-Seub Ahn, Seong-Hwan Woo, Sungmin Kim, Jun-Hyuk Lim, Tae-Hoon An, Myung-Sun Kim
BACKGROUND: The ideal treatment of terrble triad injuries and whether fixation of coronoid process fractures is needed or not are still debated. Therefore, we aimed to investigate if terrible triad injuries necessitate coronoid fracture fixation and evaluate if non-fixation treatments have similar efficacies and outcomes as fixation-treatments in cases of terrible triad injuries. METHODS: From August 2011 to July 2020, 23 patients with acute terrible triad injuries without involvement of the anteromedial facet of the coronoid process were included to evaluate the postoperative clinical and radiological outcomes (minimum follow-up of 20 months)...
April 25, 2024: BMC Surgery
https://read.qxmd.com/read/38664273/predictors-of-failure-after-primary-anterior-cervical-discectomy-and-fusion-for-subaxial-traumatic-spine-injuries
#8
JOURNAL ARTICLE
Aman Singh, Victor Gabriel El-Hajj, Alexander Fletcher-Sandersjöö, Nabeel Aziz, Abdul Karim Ghaith, Charles Tatter, Simon Blixt, Gunnar Nilsson, Mohamad Bydon, Paul Gerdhem, Erik Edström, Adrian Elmi-Terander
INTRODUCTION: Traumatic subaxial fractures account for more than half of all cervical spine injuries. The optimal surgical approach is a matter of debate and may include anterior, posterior or a combined anteroposterior (360º) approach. Analyzing a cohort of patients initially treated with anterior cervical discectomy and fusion (ACDF) for traumatic subaxial injuries, the study aimed to identify predictors for treatment failure and the subsequent need for supplementary posterior fusion (PF)...
April 25, 2024: European Spine Journal
https://read.qxmd.com/read/38652258/anatomical-features-of-the-proximal-end-of-the-radius-and-its-implications-for-implant-design
#9
JOURNAL ARTICLE
Bahattin Paslı, Helin Yücedağ Gündoğdu, Mehmet Ülkir, Burcu Erçakmak Güneş
PURPOSE: The proximal radio-ulnar joint allows supination and pronation of the forearm and the humeroradial joint allows flexion and extension movements at the elbow joint. Although the proximal end of the radius is less common than other fractures, it is more common nowadays due to the prolongation of life expectancy, increased incidence of osteoporosis. There have been reports in the literature that success has not been achieved due to the lack of anatomical fit of the prosthesis. Knowledge of the morphometric features of the proximal end of the radius is important for the design of anatomically and biomechanically appropriate prostheses...
April 23, 2024: Surgical and Radiologic Anatomy: SRA
https://read.qxmd.com/read/38651571/the-tibial-capsular-reflection-and-septum-in-posterior-compartment-are-safe-and-reliable-soft-tissue-landmark-for-tibial-tunnel-drilling-in-posterior-cruciate-ligament-reconstruction
#10
JOURNAL ARTICLE
Yingzhen Niu, Zhikuan Li, Zhen Chen, Yi Zheng, Zhenfeng Zhang, Zhuangdai Zhang, Jun Ma, Jiangtao Dong
PURPOSE: To investigate the validity of using tibial capsular reflection and septum in the posterior compartment as landmark during posterior cruciate ligament (PCL) reconstruction (PCLR). METHODS: Anatomic measurements were obtained for 12 fresh human cadaveric knee specimens to observe the spatial position of the tibial insertion of the PCL in relation to the posterior septum and the capsular reflection in the posterior compartment. Sixty patients who underwent reconstruction of the PCL between 2020 and 2023 were also retrospectively investigated...
April 23, 2024: Knee Surgery, Sports Traumatology, Arthroscopy
https://read.qxmd.com/read/38648675/incidental-durotomy-resulting-in-a-postoperative-lumbosacral-nerve-root-with-eventration-into-the-adjacent-facet-joint-illustrative-cases
#11
JOURNAL ARTICLE
Michael J Kelly, Franziska C S Altorfer, Marco D Burkhard, Russel C Huang, Frank P Cammisa, J Levi Chazen
BACKGROUND: Radicular pain after lumbar decompression surgery can result from epidural hematoma/seroma, recurrent disc herniation, incomplete decompression, or other rare complications. A less recognized complication is postoperative nerve root herniation, resulting from an initially unrecognized intraoperative or, more commonly, a spontaneous postoperative durotomy. Rarely, this nerve root herniation can become entrapped within local structures, including the facet joint. The aim of this study was to illustrate our experience with three cases of lumbosacral nerve root eventration into an adjacent facet joint and to describe our diagnostic and surgical approach to this rare complication...
April 22, 2024: J Neurosurg Case Lessons
https://read.qxmd.com/read/38647605/development-and-validation-of-a-nomogram-to-predict-the-risk-of-residual-low-back-pain-after-tubular-microdiskectomy-of-lumbar-disk-herniation
#12
JOURNAL ARTICLE
Fengzhao Zhu, Dongqing Jia, Yaqing Zhang, Chencheng Feng, Yan Peng, Ya Ning, Xue Leng, Jianmin Li, Yue Zhou, Changqing Li, Bo Huang
OBJECTIVE: Tubular microdiskectomy (tMD) is one of the most commonly used for treating lumbar disk herniation. However, there still patients still complain of persistent postoperative residual low back pain (rLBP) postoperatively. This study attempts to develop a nomogram to predict the risk of rLBP after tMD. METHODS: The patients were divided into non-rLBP (LBP VAS score < 2) and rLBP (LBP VAS score ≥ 2) group...
April 22, 2024: European Spine Journal
https://read.qxmd.com/read/38643655/sequential-treatment-of-concomitant-odontoid-fracture-and-lower-cervical-fracture-dislocation-a-case-report
#13
Yuanchen Zhu, Jin Qian, Hanfeng Hu, Feng Zhou, Huilin Yang, Jinhui Shi
INTRODUCTION AND IMPORTANCE: To report the sequential treatment of a Type II odontoid fracture combined with a severe lower cervical (C6-7) fracture-dislocation featuring bilateral facet joint interlocking. CASE PRESENTATION: A 58-year-old male who had suffered an injury in a car accident, He presented neck pain and extremity paralysis. His neurological function was classified as per the American Spinal Injury Association (ASIA) impairment scale as Grade A, indicating complete deficits below the C6 spinal cord level...
April 20, 2024: International Journal of Surgery Case Reports
https://read.qxmd.com/read/38642627/a-framework-for-longitudinal-latent-factor-modelling-of-treatment-response-in-clinical-trials-with-applications-to-psoriatic-arthritis-and-rheumatoid-arthritis
#14
JOURNAL ARTICLE
Fabian Falck, Xuan Zhu, Sahra Ghalebikesabi, Matthias Kormaksson, Marc Vandemeulebroecke, Cong Zhang, Ruvie Martin, Stephen Gardiner, Chun Hei Kwok, Dominique M West, Luis Santos, Chengeng Tian, Yu Pang, Aimee Readie, Gregory Ligozio, Kunal K Gandhi, Tom Nichols, Ann-Marie Mallon, Luke Kelly, David Ohlssen, George Nicholson
OBJECTIVE: Clinical trials involve the collection of a wealth of data, comprising multiple diverse measurements performed at baseline and follow-up visits over the course of a trial. The most common primary analysis is restricted to a single, potentially composite endpoint at one time point. While such an analytical focus promotes simple and replicable conclusions, it does not necessarily fully capture the multi-faceted effects of a drug in a complex disease setting. Therefore, to complement existing approaches, we set out here to design a longitudinal multivariate analytical framework that accepts as input an entire clinical trial database, comprising all measurements, patients, and time points across multiple trials...
April 18, 2024: Journal of Biomedical Informatics
https://read.qxmd.com/read/38635483/asymmetrical-atrophy-of-the-paraspinal-muscles-in-patients-undergoing-unilateral-lumbar-medial-branch-radiofrequency-neurotomy
#15
JOURNAL ARTICLE
Ali E Guven, Gisberto Evangelisti, Marco D Burkhard, Paul Köhli, Jan Hambrecht, Jiaqi Zhu, Erika Chiapparelli, Michael Kelly, Koki Tsuchiya, Krizia Amoroso, Arman Zadeh, Jennifer Shue, Ek Tsoon Tan, Andrew A Sama, Federico P Girardi, Frank P Cammisa, Alexander P Hughes
Lumbar medial branch radiofrequency neurotomy (RFN), a common treatment for chronic low back pain due to facet joint osteoarthritis (FJOA), may amplify paraspinal muscle atrophy due to denervation. This study aimed to investigate the asymmetry of paraspinal muscle morphology change in patients undergoing unilateral lumbar medial branch RFN. Data from patients who underwent RFN between March 2016 and October 2021 were retrospectively analyzed. Lumbar foramina stenosis (LFS), FJOA, and fatty infiltration (FI) functional cross-sectional area (fCSA) of the paraspinal muscles were assessed on preinterventional and minimum 2-year postinterventional MRI...
March 22, 2024: Pain
https://read.qxmd.com/read/38633668/segment-selection-for-fusion-and-artificial-disc-replacement-in-the-hybrid-surgical-treatment-of-noncontiguous-cervical-spondylosis-a-finite-element-analysis
#16
JOURNAL ARTICLE
Xiangyao Sun, Jiang Huang, Qingming Zhang, Li Cao, Yuqi Liu, Zelong Song, Wei Tang, Siyuan Sun, Juyong Wang
Introduction: The treatment of skip-level cervical degenerative disease (CDD) with no degenerative changes observed in the intervening segment (IS) is complicated. This research aims to provide a reference basis for selecting treatment approaches for noncontiguous CDD. Methods: To establish accurate finite element models (FEMs), this study included computed tomography (CT) data from 21 patients with CDD (10 males and 11 females) for modeling. The study primarily discusses four cross-segment surgical approaches: upper (C3/4) anterior cervical discectomy and fusion (ACDF) and lower (C5/6) cervical disc arthroplasty (CDA), FA model; upper CDA (C3/4) and lower ACDF (C5/6), AF model; upper ACDF (C3/4) and lower ACDF (C5/6), FF model; upper CDA (C3/4) and lower CDA (C5/6), AA model...
2024: Frontiers in Bioengineering and Biotechnology
https://read.qxmd.com/read/38611668/deep-learning-detection-and-segmentation-of-facet-joints-in-ultrasound-images-based-on-convolutional-neural-networks-and-enhanced-data-annotation
#17
JOURNAL ARTICLE
Lingeer Wu, Di Xia, Jin Wang, Si Chen, Xulei Cui, Le Shen, Yuguang Huang
The facet joint injection is the most common procedure used to release lower back pain. In this paper, we proposed a deep learning method for detecting and segmenting facet joints in ultrasound images based on convolutional neural networks (CNNs) and enhanced data annotation. In the enhanced data annotation, a facet joint was considered as the first target and the ventral complex as the second target to improve the capability of CNNs in recognizing the facet joint. A total of 300 cases of patients undergoing pain treatment were included...
April 2, 2024: Diagnostics
https://read.qxmd.com/read/38606327/best-practice-guidelines-for%C3%A2-clinical-and%C3%A2-radiological-assessment-of%C3%A2-patients-with-femoroacetabular-impingement-results-from-the-isha-international-delphi-consensus-project-phase-2
#18
JOURNAL ARTICLE
Sarkhell Radha, Jonathan Hutt, Ajay Lall, Benjamin Domb, T Sean Lynch, Damian Griffin, Richard E Field, Josip Chuck-Cakic
In 2018, the International Society for Hip Preservation Surgery (ISHA) initiated a series of Delphi consensus studies to identify the global hip preservation community's current opinion on best practices for different facets of hip preservation surgery. Arthroscopic procedures to treat hip pathologies, such as femoroacetabular impingement syndrome (FAIS) are now established in mainstream orthopaedic practice. This study establishes recommendations for the investigation of patients with suspected FAIS. The investigation has focused on the three phases of the diagnostic process-patient history, physical examination and special investigations...
January 2024: Journal of Hip Preservation Surgery
https://read.qxmd.com/read/38601321/anatomy-of-the-naviculocuneiform-joint-complex
#19
JOURNAL ARTICLE
George Borrelli, Maxwell Albiero, James Jastifer
BACKGROUND: The purpose of this study was to quantify the articular surfaces of the naviculocuneiform (NC) joint to help clinicians better understand common pathologies observed such as navicular stress fractures and arthrodesis nonunions. METHODS: Twenty cadaver NC joints were dissected and the articular cartilage of the navicular, medial, middle, and lateral cuneiforms were quantified by calibrated digital imaging software. Statistical analysis included calculating the mean cartilage surface area dimensions of the distal navicular and proximal cuneiform bones...
April 2024: Foot & ankle orthopaedics
https://read.qxmd.com/read/38600941/analyzing-isolated-degeneration-of-lumbar-facet-joints-implications-for-degenerative-instability-and-lumbar-biomechanics-using-finite-element-analysis
#20
JOURNAL ARTICLE
Jun Sung Park, Tae Sik Goh, Jung Sub Lee, Chiseung Lee
The facet joint contributes to lumbar spine stability as it supports the weight of body along with the intervertebral discs. However, most studies on the causes of degenerative lumbar diseases focus on the intervertebral discs and often overlook the facet joints. This study aimed to investigate the impact of facet joint degeneration on the degenerative changes and diseases of the lumbar spine. A finite element model of the lumbar spine (L1-S1) was fabricated and validated to study the biomechanical characteristics of the facet joints...
2024: Frontiers in Bioengineering and Biotechnology
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