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https://www.readbyqxmd.com/read/28534852/effects-of-ketogenic-diets-on-cardiovascular-risk-factors-evidence-from-animal-and-human-studies
#1
REVIEW
Christophe Kosinski, François R Jornayvaz
The treatment of obesity and cardiovascular diseases is one of the most difficult and important challenges nowadays. Weight loss is frequently offered as a therapy and is aimed at improving some of the components of the metabolic syndrome. Among various diets, ketogenic diets, which are very low in carbohydrates and usually high in fats and/or proteins, have gained in popularity. Results regarding the impact of such diets on cardiovascular risk factors are controversial, both in animals and humans, but some improvements notably in obesity and type 2 diabetes have been described...
May 19, 2017: Nutrients
https://www.readbyqxmd.com/read/28529463/nutrition-practices-and-knowledge-among-ncaa-division-iii-football-players
#2
Elizabeth Lea Abbey, Cynthia Joy Wright, Christina M Kirkpatrick
BACKGROUND: Participation in collegiate American football is physically demanding and may have long-term health implications, particularly in relation to cardiovascular and neurological health. National Collegiate Athletic Association (NCAA) Division III (DIII) football players are a relatively unstudied population, particularly in terms of their dietary habits and knowledge. The aim of the present study was to descriptively evaluate the dietary intake of DIII football players including a subset of linemen and assess the nutritional knowledge and sources of information of these athletes...
2017: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/28526391/withdrawal-from-high-carbohydrate-high-saturated-fat-diet-changes-saturated-fat-distribution-and-improves-hepatic-low-density-lipoprotein-receptor-expression-to-ameliorate-metabolic-syndrome-in-rats
#3
Ankita Hazarika, Himadri Kalita, Mohan Chandra Kalita, Rajlakshmi Devi
OBJECTIVE: The "lipid hypothesis" determined that saturated fatty acid (SFA) raises low-density lipoprotein cholesterol, thereby increasing the risk for metabolic syndrome (MetS). The aim of this study was to investigate the effect of subchronic withdrawal from a high-carbohydrate, high-saturated fat (HCHF) diet during MetS with reference to changes in deleterious SFA (C12:0, lauric acid; C14:0, myristic acid; C16:0, palmitic acid; C18:0, stearic acid) distribution in liver, white adipose tissue (WAT), and feces...
June 2017: Nutrition
https://www.readbyqxmd.com/read/28525543/fermentable-carbohydrates-fodmaps-exacerbate-functional-gastrointestinal-symptoms-in-patients-with-inflammatory-bowel-disease-a-randomised-double-blind-placebo-controlled-cross-over-re-challenge-trial
#4
Selina R Cox, Alexis C Prince, Clio E Myers, Peter M Irving, James O Lindsay, Miranda C Lomer, Kevin Whelan
Background and Aims: Preliminary evidence suggests fermentable carbohydrate restriction might ameliorate functional gastrointestinal symptoms (FGS) in quiescent inflammatory bowel disease (IBD). Our aim was to determine whether fermentable carbohydrates exacerbate FGS in quiescent IBD using a randomised, double-blinded, placebo-controlled, cross-over, re-challenge trial. Methods: Patients with quiescent IBD and FGS responsive to a low FODMAP diet were allocated to a series of 3-day fermentable carbohydrate challenges in random order (fructan, 12 g/d; galacto-oligosaccharides, GOS, 6 g/d; sorbitol, 6 g/d; and glucose placebo, 12 g/d), each separated by a standardised washout period...
May 19, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28521699/food-and-gastroesophageal-reflux-disease
#5
Teodora Surdea-Blaga, Dana E Negrutiu, Mariana Palage, Dan L Dumitrascu
Gastroesophageal reflux disease is a chronic condition with a high prevalence in western countries. Transient lower esophageal sphincter relaxation episodes and a decreased lower esophageal sphincter pressure are the main mechanisms involved. Currently used drugs are efficient on reflux symptoms, but only as long as they are administered, because they do not modify the reflux barrier. Certain nutrients or foods are generally considered to increase the frequency of gastroesophageal reflux symptoms, therefore physicians recommend changes in diet and some patients avoid bothering foods...
May 15, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28521681/effects-of-diets-on-adipose-tissue
#6
Silvia Ezquerro, Amaia Rodríguez, Piero Portincasa, Gema Frühbeck
Obesity is a major health problem that has become a global epidemic. Overweight and obesity are commonly associated with the development of several pathologies, such as insulin resistance, cardiovascular diseases, sleep apnea and several types of cancer, which can lead to further morbidity and mortality. An increased abdominal adiposity renders overweight and obese individuals more prone to metabolic and cardiovascular problems. In this sense, excess adiposity leads to several changes in the biology, morphology and function of the adipose tissue, such as adipocyte hypertrophy and hyperplasia, adipose tissue inflammation and fibrosis and an impaired secretion of adipokines, contributing to the onset of obesity-related co-morbidities...
May 17, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28511163/-impact-of-physical-activity-on-anthropometric-indices-in-patients-with-nonalcoholic-fatty-liver-disease-and-pre-diabetes-or-type-2-diabetes
#7
Віталіна В Івачевська
INTRODUCTION: Nonalcoholic fatty liver disease (NAFLD) is currently the most common cause of chronic liver disease in many developed countries. The first step, which is offered to all patients with NAFLD includes lifestyle modifications, low-calorie diet, increased physical activity and giving up smoking. OBJECTIVE: to evaluate the efficiency of the daily 30-minute walking at a fast pace on the dynamics of anthropometric indices in patients with NAFLD and pre-diabetes or type 2 diabetes...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28509665/evaluation-of-diet-pattern-and-weight-gain-in-postmenopausal-women-enrolled-in-the-women-s-health-initiative-observational-study
#8
Christopher Ford, Shine Chang, Mara Z Vitolins, Jenifer I Fenton, Barbara V Howard, Jinnie J Rhee, Marcia Stefanick, Bertha Chen, Linda Snetselaar, Rachel Urrutia, Alexis C Frazier-Wood
It is unclear which of four popular contemporary diet patterns is best for weight maintenance among postmenopausal women. Four dietary patterns were characterised among postmenopausal women aged 49-81 years (mean 63·6 (sd 7·4) years) from the Women's Health Initiative Observational Study: (1) a low-fat diet; (2) a reduced-carbohydrate diet; (3) a Mediterranean-style (Med) diet; and (4) a diet consistent with the US Department of Agriculture's Dietary Guidelines for Americans (DGA). Discrete-time hazards models were used to compare the risk of weight gain (≥10 %) among high adherers of each diet pattern...
May 16, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28502704/ketogenic-diet-leads-to-o-glcnac-modification-in-the-btbr-t-tf-j-mouse-model-of-autism
#9
Christopher Newell, Virginia L Johnsen, Nellie C Yee, Warren J Xu, Matthias S Klein, Aneal Khan, Jong M Rho, Jane Shearer
BACKGROUND: Protein O-linked-β-N-acetyl glucosamine (O-GlcNAc) is a post-translational modification to Ser/Thr residues that integrates energy supply with demand. Abnormal O-GlcNAc patterning is evident in several neurological disease states including epilepsy, Alzheimer's disease and autism spectrum disorder (ASD). A potential treatment option for these disorders includes the high-fat, low-carbohydrate, ketogenic diet (KD). The goal of this study was to determine whether the KD induces changes in O-GlcNAc in the BTBR(T+tf/j) (BTBR) mouse model of ASD...
May 11, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28502489/dietary-carbohydrate-and-fat-intakes-are-differentially-associated-with-lipid-abnormalities-in-korean-adults
#10
SuJin Song, Won O Song, YoonJu Song
BACKGROUND: A high prevalence of metabolic syndrome along with increasing rates of low high-density lipoprotein cholesterol (HDL-C) and elevated triglycerides (TGs) is shown in Korean adults. Little is known about the associations between macronutrient intake and lipid abnormalities in the Asian population, whose major energy source is carbohydrates. OBJECTIVE: We examined the associations of dietary carbohydrate and fat intakes with lipid abnormalities in Korean adults...
March 2017: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/28501343/changes-of-renal-sinus-fat-and-renal-parenchymal-fat-during-an-18-month-randomized-weight-loss-trial
#11
Hila Zelicha, Dan Schwarzfuchs, Ilan Shelef, Yftach Gepner, Gal Tsaban, Lilac Tene, Anat Yaskolka Meir, Avital Bilitzky, Oded Komy, Noa Cohen, Nitzan Bril, Michal Rein, Dana Serfaty, Shira Kenigsbuch, Yoash Chassidim, Benjamin Sarusi, Joachim Thiery, Uta Ceglarek, Michael Stumvoll, Matthias Blüher, Yosef S Haviv, Meir J Stampfer, Assaf Rudich, Iris Shai
BACKGROUND & AIMS: Data regarding the role of kidney adiposity, its clinical implications, and its dynamics during weight-loss are sparse. We investigated the effect of long-term weight-loss induced intervention diets on dynamics of renal-sinus-fat, an ectopic fat depot, and %renal-parenchymal-fat, lipid accumulation within the renal parenchyma. METHODS: We randomized 278 participants with abdominal obesity/dyslipidemia to low-fat or Mediterranean/low-carbohydrate diets, with or without exercise...
May 2, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28495873/intestinal-digestive-enzyme-modulation-in-house-sparrow-nestlings-occurs-within-24-hours-of-a-change-in-diet-composition
#12
Katherine H Rott, Enrique Caviedes-Vidal, William H Karasov
Nestling house sparrows near fledging age (12 days) were previously found to reversibly modulate the activity of their intestinal digestive enzymes in response to changes in diet composition. However, it is not known how quickly nestlings can adjust to new diets with different substrate compositions, nor is it known how early in life nestlings can modulate their enzyme activity in response to changes in diet. In the current study, 3-day-old nestlings were captured from the wild and fed and switched among contrasting diets - one high in protein and low in carbohydrate and another higher in carbohydrate and with lower but adequate protein - in order to determine (1) how quickly house sparrow nestlings could adjust to changes in diet composition, (2) how early in life nestlings could modulate their digestive enzyme activity in response to these changes, and (3) which digestive enzymes could be modulated in house sparrow nestlings earlier in life...
May 11, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/28489143/the-use-of-a-formula-based-ketogenic-diet-in-children-with-refractory-epilepsy
#13
Letícia Pereira de Brito Sampaio, Cristina Takakura, Maria Luiza Giraldes de Manreza
The ketogenic diet (KD) is a nonpharmacologic treatment that has been used for refractory epilepsy since 1921. The KD is a high-fat, low-carbohydrate, and restricted protein diet, which is calculated and weighed for each individual patient. Introducing and maintaining the diet for a long time remains a challenge. In this study, we evaluated the acceptability, tolerance, and efficacy of a formula-based KD in 10 children with refractory epilepsy. The ketogenic formula tested herein caused only mild KD-related adverse events and adequate adherence...
April 2017: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/28476546/infantile-gangliosidoses-mapping-a-timeline-of-clinical-changes
#14
Jeanine R Jarnes Utz, Sarah Kim, Kelly King, Richard Ziegler, Lynn Schema, Evelyn S Redtree, Chester B Whitley
BACKGROUND: Infantile gangliosidoses include GM1 gangliosidosis and GM2 gangliosidosis (Tay-Sachs disease, Sandhoff disease). To date, natural history studies in infantile GM2 (iGM2) have been retrospective and conducted through surveys. Compared to iGM2, there is even less natural history information available on infantile GM1 disease (iGM1). There are no approved treatments for infantile gangliosidoses. Substrate reduction therapy using miglustat has been tried, but is limited by gastrointestinal side effects...
April 29, 2017: Molecular Genetics and Metabolism
https://www.readbyqxmd.com/read/28474196/molecular-characterization-of-fructose-1-6-bisphosphatase-1b-in-blunt-snout-bream-megalobrama-amblycephala-and-the-transcriptional-response-to-glucose-loading-after-the-adaptation-to-high-carbohydrate-diets
#15
Xiang-Fei Li, Chao Xu, Guang-Zhen Jiang, Ding-Dong Zhang, Wen-Bin Liu
This study aimed to characterize the full-length complementary DNA (cDNA) of fructose-1,6-bisphosphatase 1b (FBP1b) from fish Megalobrama amblycephala, and investigate its transcriptional response to glucose administration after the adaptation to high-carbohydrate diets. The cDNA obtained covered 1435 bp with an open reading frame of 1014 bp. Sequence alignment and phylogenetic analysis revealed a high degree of conservation (76-96%) among most fish and other vertebrates, retaining one N-linked glycosylation site, one N-terminal acetylation site, 13 phosphorylation sites, one fructose-1,6-bisphosphatase (FBPase) active site, five metal-binding sites, four substrate-binding sites, and several AMP-binding sites...
May 4, 2017: Fish Physiology and Biochemistry
https://www.readbyqxmd.com/read/28469746/low-carbohydrate-high-fat-diet-can-it-help-exercise-performance
#16
Chen-Kang Chang, Katarina Borer, Po-Ju Lin
Low-carbohydrate-high-fat (LCHF) diets have been used as a means of weight loss and control of symptoms in several clinical conditions. There is emerging evidence that the metabolic changes induced by LCHF diets enhance endurance performance. The aims of this review are to examine the evidence of LCHF diets in improving various aspects of athletic performance. Long-term LCHF dietary intake may help control body weight and fat mass while maintaining lean body mass in athletes in weight-sensitive sports. LCHF-adapted endurance athletes can reach the maximal fat oxidation rate of approximately 1...
February 2017: Journal of Human Kinetics
https://www.readbyqxmd.com/read/28466507/effects-of-dietary-approach-to-stop-hypertension-diet-on-androgens-antioxidant-status-and-body-composition-in-overweight-and-obese-women-with-polycystic-ovary-syndrome-a-randomised-controlled-trial
#17
M Azadi-Yazdi, M Karimi-Zarchi, A Salehi-Abargouei, H Fallahzadeh, A Nadjarzadeh
BACKGROUND: Polycystic ovary syndrome (PCOS) is the most common endocrine disease in reproductive age women. The present study aimed to determine the effects of Dietary Approaches to Stop Hypertension (DASH) diet on reproductive hormones, plasma total antioxidant status and anthropometric indices in overweight and obese PCOS women. METHODS: In this randomised controlled clinical trial, 60 women with PCOS were randomly assigned to one of two diets with energy restriction: the DASH diet and a control diet...
June 2017: Journal of Human Nutrition and Dietetics: the Official Journal of the British Dietetic Association
https://www.readbyqxmd.com/read/28465837/a-moderate-zinc-deficiency-does-not-alter-lipid-and-fatty-acid-composition-in-the-liver-of-weanling-rats-fed-diets-rich-in-cocoa-butter-or-safflower-oil
#18
Edgar Weigand, Jennifer Egenolf
The aim of the study was to examine whether a moderate zinc deficiency alters hepatic lipid composition. Male weanling rats, assigned to five groups (8 animals each), were fed low-carbohydrate high-fat diets supplemented with 7 or 50 mg Zn/kg (LZ or HZ) and 22% cocoa butter (CB) or 22% safflower oil (SF) for four weeks. One group each had free access to the LZ-CB and LZ-SF diets, one group each was restrictedly fed the HZ-CB and HZ-SF diets in matching amounts, and one group had free access to the HZ-SF diet (ad libitum control)...
2017: Journal of Nutrition and Metabolism
https://www.readbyqxmd.com/read/28464099/endogenous-phosphorus-losses-in-growing-finishing-pigs-and-gestating-sows
#19
P Bikker, C M C van der Peet-Schwering, W J J Gerrits, V Sips, C Walvoort, H van Laar
An experiment was conducted to determine the effects of diet composition, feeding level (FL), and BW on endogenous phosphorous losses (EPL) using growing-finishing (GF) pigs and sows. After an adaptation period, 48 GF pigs (initial BW 90.5 kg) and 48 just-weaned sows (initial BW 195 kg), both individually housed, were allotted to 12 dietary treatments in a 2 × 3 × 2 factorial arrangement. Treatments were animal type (GF pigs or sows), diet composition (a semipurified starch (STA), inulin (INU), or lignocellulose (CEL) based low-P diet), and FL (2...
April 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28460919/effect-of-lactulose-derived-oligosaccharides-on-intestinal-microbiota-during-the-shift-between-media-with-different-energy-contents
#20
Elvira Barroso, Antonia Montilla, Nieves Corzo, Carmen Peláez, M Carmen Martínez-Cuesta, Teresa Requena
The microbiological and metabolic changes of an overweight-associated colonic microbiota after reducing in vitro the carbohydrate supply and its supplementation with oligosaccharides derived from lactulose (OsLu) were evaluated using a dynamic simulator of the gastrointestinal tract. The differentiation and stability of the microbial communities within each colon compartment were reached after two weeks of feeding the system with a high energy (HE) medium based on fructose and readily fermentable starches. The effect of reducing the energy content (low-energy medium, LE) and the supplementation with OsLu caused minor variations in bacterial counts, except for Enterobacteriaceae...
November 2016: Food Research International
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