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resynchronisation therapy

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https://www.readbyqxmd.com/read/27836874/assessment-of-cardiac-resynchronisation-therapy-in-patients-with-wide-qrs-and-non-specific-intraventricular-conduction-delay-rationale-and-design-of-the-multicentre-randomised-nicd-crt-study
#1
Romain Eschalier, Sylvain Ploux, Bruno Pereira, Nicolas Clémenty, Antoine Da Costa, Pascal Defaye, Stéphane Garrigue, Jean-Baptiste Gourraud, Daniel Gras, Benoît Guy-Moyat, Christophe Leclercq, Pierre Mondoly, Pierre Bordachar
INTRODUCTION: Cardiac resynchronisation therapy (CRT) was initially developed to treat patients with left bundle branch block (LBBB). However, many patients with heart failure have a widened QRS but neither left-BBB nor right-BBB; this is called non-specific intraventricular conduction delay (NICD). It is unclear whether CRT is effective in this subgroup of patients. METHODS AND ANALYSIS: The NICD-CRT study is a prospective, double-blind, randomised (1:1), parallel-arm, multicentre trial comparing the effects of CRT in patients with heart failure, a reduced left ventricular ejection fraction (LVEF <35%) and NICD, who have been implanted with a device (CRT-pacemaker or CRT-defibrillator) that has or has not been activated...
November 11, 2016: BMJ Open
https://www.readbyqxmd.com/read/27770718/a-framework-for-combining-a-motion-atlas-with-non-motion-information-to-learn-clinically-useful-biomarkers-application-to-cardiac-resynchronisation-therapy-response-prediction
#2
Devis Peressutti, Matthew Sinclair, Wenjia Bai, Thomas Jackson, Jacobus Ruijsink, David Nordsletten, Liya Asner, Myrianthi Hadjicharalambous, Christopher A Rinaldi, Daniel Rueckert, Andrew P King
We present a framework for combining a cardiac motion atlas with non-motion data. The atlas represents cardiac cycle motion across a number of subjects in a common space based on rich motion descriptors capturing 3D displacement, velocity, strain and strain rate. The non-motion data are derived from a variety of sources such as imaging, electrocardiogram (ECG) and clinical reports. Once in the atlas space, we apply a novel supervised learning approach based on random projections and ensemble learning to learn the relationship between the atlas data and some desired clinical output...
October 11, 2016: Medical Image Analysis
https://www.readbyqxmd.com/read/27677744/cardiac-sympathetic-activity-in-chronic-heart-failure-cardiac-123-i-mibg-scintigraphy-to-improve-patient-selection-for-icd-implantation
#3
REVIEW
D O Verschure, B L F van Eck-Smit, G A Somsen, R J J Knol, H J Verberne
Heart failure is a life-threatening disease with a growing incidence in the Netherlands. This growing incidence is related to increased life expectancy, improvement of survival after myocardial infarction and better treatment options for heart failure. As a consequence, the costs related to heart failure care will increase. Despite huge improvements in treatment, the prognosis remains unfavourable with high one-year mortality rates. The introduction of implantable devices such as implantable cardioverter defibrillators (ICD) and cardiac resynchronisation therapy (CRT) has improved the overall survival of patients with chronic heart failure...
December 2016: Netherlands Heart Journal
https://www.readbyqxmd.com/read/27617084/cardiac-resynchronisation-therapy-the-optimal-qrs-duration-revisited
#4
(no author information available yet)
No abstract text is available yet for this article.
August 2016: Arrhythmia & Electrophysiology Review
https://www.readbyqxmd.com/read/27561286/utilisation-of-cardiac-pacemakers-over-a%C3%A2-20-year-period-results-from-a%C3%A2-nationwide-pacemaker-registry
#5
L M de Vries, W A Dijk, C A M Hooijschuur, M J G Leening, B H C Stricker, N M van Hemel
The implantation of cardiac pacemakers has become a well-established therapy for conduction disorders and sinus node dysfunction. In many countries pacemaker registries have been initiated in order to collect information on patient characteristics, trends in numbers and the types of pacemakers used, to identify problematic devices, and for safety monitoring. For this utilisation study the Central Pacemaker Patients Registration (CPPR) from the Netherlands Pacemaker Registry Foundation (CPPR-SPRN) containing data collected for more than 20 years was used...
August 25, 2016: Netherlands Heart Journal
https://www.readbyqxmd.com/read/27560277/rate-control-in-atrial-fibrillation
#6
REVIEW
Isabelle C Van Gelder, Michiel Rienstra, Harry J G M Crijns, Brian Olshansky
Control of the heart rate (rate control) is central to atrial fibrillation management, even for patients who ultimately require control of the rhythm. We review heart rate control in patients with atrial fibrillation, including the rationale for the intervention, patient selection, and the treatments available. The choice of rate control depends on the symptoms and clinical characteristics of the patient, but for all patients with atrial fibrillation, rate control is part of the management. Choice of drugs is patient-dependent...
August 20, 2016: Lancet
https://www.readbyqxmd.com/read/27537190/transcatheter-mitral-valve-implantation-30-day-outcome-of-first-in-man-experience-with-an-apically-tethered-device
#7
Cesare Quarto, Simon Davies, Alison Duncan, Alistair Lindsay, Georg Lutter, Lucian Lozonschi, Neil Moat
OBJECTIVE: A small number of transcatheter mitral valve implants (TMVIs) have been reported using devices designed to treat secondary mitral regurgitation (MR). However, MR has many etiologies, and patients have a broad spectrum of annular size, geometry, and lesions. There are a number of technical challenges for TMVI including left ventricular outflow tract obstruction and paravalvular MR. Thirty days' outcome of first-in-man implants with a novel TMVI device is reported. METHODS: The Tendyne TMVI system consists of a porcine pericardial valve in a tethered nitinol frame...
May 2016: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/27475261/pacemaker-use-in-new-zealand-data-from-the-new-zealand-implanted-cardiac-device-registry-anzacs-qi-15
#8
P D Larsen, A J Kerr, M Hood, S A Harding, D Hooks, D Heaven, N A Lever, S Sinclair, D Boddington, E W Tang, J Swampillai, M K Stiles
BACKGROUND: The New Zealand Cardiac Implanted Device Registry (Device) has recently been developed under the auspices of the New Zealand Branch of the Cardiac Society of Australia and New Zealand. This study describes the initial Device registry cohort of patients receiving a new pacemaker, their indications for pacing and their perioperative complications. METHODS: The Device Registry was used to audit patients receiving a first pacemaker between 1(st) January 2014 and 1(st) June 2015...
July 19, 2016: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/27440409/overview-of-implantable-cardioverter-defibrillator-and-cardiac-resynchronisation-therapy-in-heart-failure-management
#9
Pow-Li Chia, David Foo
Clinical trials have established the benefits of implantable cardioverter defibrillators (ICDs) and cardiac resynchronisation therapy (CRT) in the treatment of heart failure patients. As adjuncts to guideline-directed medical therapy, ICDs confer mortality benefits from sudden cardiac arrest, while CRT reduces mortality, hospitalisation rates and improves functional capacity. This review discusses the use of ICDs and CRT devices in heart failure management, outlining the evidence supporting their use, indications and contraindications...
July 2016: Singapore Medical Journal
https://www.readbyqxmd.com/read/27439396/remote-monitoring-of-patients-with-cardiac-implantable-electronic-devices-a-southeast-asian-single-centre-pilot-study
#10
Paul Chun Yih Lim, Audry Shan Yin Lee, Kelvin Chi Ming Chua, Eric Tien Siang Lim, Daniel Thuan Tee Chong, Boon Yew Tan, Kah Leng Ho, Wee Siong Teo, Chi Keong Ching
INTRODUCTION: Remote monitoring of cardiac implantable electronic devices (CIED) has been shown to improve patient safety and reduce in-office visits. We report our experience with remote monitoring via the Medtronic CareLink(®) network. METHODS: Patients were followed up for six months with scheduled monthly remote monitoring transmissions in addition to routine in-office checks. The efficacy of remote monitoring was evaluated by recording compliance to transmissions, number of device alerts requiring intervention and time from transmission to review...
July 2016: Singapore Medical Journal
https://www.readbyqxmd.com/read/27411837/cost-effectiveness-of-implantable-cardiac-devices-in-patients-with-systolic-heart-failure
#11
Stuart Mealing, Beth Woods, Neil Hawkins, Martin R Cowie, Christopher J Plummer, William T Abraham, John F Beshai, Helmut Klein, Mark Sculpher
OBJECTIVE: To evaluate the cost-effectiveness of implantable cardioverter defibrillators (ICDs), cardiac resynchronisation therapy pacemakers (CRT-Ps) and combination therapy (CRT-D) in patients with heart failure with reduced ejection fraction based on a range of clinical characteristics. METHODS: Individual patient data from 13 randomised trials were used to inform a decision analytical model. A series of regression equations were used to predict baseline all-cause mortality, hospitalisation rates and health-related quality of life and device-related treatment effects...
November 1, 2016: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/27374933/cardiac-resynchronisation-therapy-device-implantation-in-a-patient-with-persistent-left-superior-vena-cava-is-it-still-a-challenge
#12
Maciej Kubala, Gagan Deep Chadha, Cédric Renard, Sarah Traullé, Jean-Sylvain Hermida
No abstract text is available yet for this article.
2016: Kardiologia Polska
https://www.readbyqxmd.com/read/27343008/early-implantation-of-primary-prevention-implantable-cardioverter-defibrillators-for-patients-with-newly-diagnosed-severe-nonischemic-cardiomyopathy
#13
Aleksandr Voskoboinik, Jason Bloom, Andrew Taylor, Justin Mariani
BACKGROUND: Primary prevention implantable cardioverter defibrillators (ICDs) reduce mortality in selected patients with severe systolic dysfunction. Current guidelines suggest a 3- to 6-month waiting period before implantation. METHODS: We retrospectively studied 29 consecutive patients with newly diagnosed nonischemic cardiomyopathy (NICM) who underwent primary prevention ICD implantation within 6 months of diagnosis between January 2008 and April 2014. Cardiac MRI (CMR) evaluated left ventricular ejection fraction (LVEF) and regional fibrosis preimplant...
September 2016: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/27335654/measures-of-endothelial-dysfunction-predict-response-to-cardiac-resynchronisation-therapy
#14
David R Warriner, Patricia Lawford, Paul J Sheridan
OBJECTIVES: Cardiac resynchronisation therapy (CRT) improves morbidity and mortality in heart failure (HF). Impaired endothelial function, as measured by flow-mediated dilation (FMD) is associated with increased morbidity and mortality in HF and may help to differentiate responders from non-responders. METHODS: 19 patients were recruited, comprising 94% men, mean age 69±8 years, New York Heart Association functional classes II-IV, QRSd 161±21 ms and mean left ventricular ejection fraction 26±8%...
2016: Open Heart
https://www.readbyqxmd.com/read/27326223/usefulness-of-cardiac-resynchronisation-therapy-devices-and-implantable-cardioverter-defibrillators-in-the-treatment-of-heart-failure-due-to-severe-systolic-dysfunction-systematic-review-of-clinical-trials-and-network-meta-analysis
#15
M A García García, M A Rosero Arenas, R Ruiz Granell, F J Chorro Gascó, A Martínez Cornejo
AIM: To assess the effectiveness of cardiac resynchronisation therapy (CRT), implantable cardioverter defibrillator (ICD) therapy, and the combination of these devices (CRT+ICD) in adult patients with left ventricular dysfunction and symptomatic heart failure. METHODS: A comprehensive systematic review of randomised clinical trials was conducted. Several electronic databases (PubMed, Embase, Ovid, Cochrane, ClinicalTrials.gov) were reviewed. The mortality rates between treatments were compared...
2016: Heart Asia
https://www.readbyqxmd.com/read/27325432/retrospective-application-of-program-to-access-and-review-trending-information-and-evaluate-correlation-to-symptoms-in-patients-with-heart-failure-criteria-for-the-remote-management-of-patients-with-cardiac-resynchronisation-therapy
#16
Francesco Ma Brasca, Jessica Franzetti, Valeria Rella, Gabriella Malfatto, Roberto Brambilla, Mario Facchini, Gianfranco Parati, Giovanni B Perego
AIM: The Program to Access and Review Trending iNformation and Evaluate coRrelation to Symptoms in patients with Heart Failure (PARTNERS HF) trial elaborated a multiparametric model for prediction of acute decompensation in advanced heart failure patients, based on periodical in office data download from cardiac resynchronisation devices. In this study, we evaluated the ability of the PARTNERS HF criteria to detect initial decompensation in a population of moderate heart failure patients under remote monitoring...
June 20, 2016: Journal of Telemedicine and Telecare
https://www.readbyqxmd.com/read/27291327/telemonitoring-in-heart-failure-patients-treated-by-cardiac-resynchronisation-therapy-with-defibrillator-crt-d-the-telecart-study
#17
C Sardu, M Santamaria, M R Rizzo, M Barbieri, M di Marino, G Paolisso, G Santulli, R Marfella
AIM: Telemonitoring (TM) is a safe and efficient monitoring system for internal cardioverter defibrillator device (ICD) recipients. TM has been used to track info on the clinical status of heart failure patients treated by ICD and/or cardiac resynchronisation therapy defibrillator (CRT-D). The aim of this study was to investigate the impact of TM on clinical outcomes in a population of CRT-D patients with heart failure. METHODS: In a multicentre, randomised study, patients with chronic heart failure, New York Heart Association (NYHA) functional class II or III, left bundle branch block, severe left ventricle ejection fraction reduction (LVEF < 35%) have been identified and screened...
July 2016: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/27256458/positive-impact-on-heat-loss-and-patient-experience-of-preheated-skin-disinfection-a-randomised-controlled-trial
#18
Camilla Wistrand, Bo Söderquist, Ulrica Nilsson
AIMS AND OBJECTIVES: The aim of this study was to compare the effect of preheated (36 °C) and room-temperature (20 °C) skin disinfectant solution on skin temperature and patients' experience of the skin disinfection process. BACKGROUND: To prevent surgical site infections, it is important to disinfect skin prior to invasive surgery. In clinical practice, conscious patients often comment on the coldness of the preoperative skin disinfection solution. Evidence is lacking, as to whether preheated skin disinfectant has any positive effects during preoperative skin disinfection...
June 3, 2016: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/27249816/clinical-utility-of-speckle-tracking-echocardiography-in-cardiac-resynchronisation-therapy
#19
REVIEW
Sitara G Khan, Dimitris Klettas, Stam Kapetanakis, Mark J Monaghan
Cardiac resynchronisation therapy (CRT) can profoundly improve outcome in selected patients with heart failure; however, response is difficult to predict and can be absent in up to one in three patients. There has been a substantial amount of interest in the echocardiographic assessment of left ventricular dyssynchrony, with the ultimate aim of reliably identifying patients who will respond to CRT. The measurement of myocardial deformation (strain) has conventionally been assessed using tissue Doppler imaging (TDI), which is limited by its angle dependence and ability to measure in a single plane...
March 2016: Echo Research and Practice
https://www.readbyqxmd.com/read/27182527/cardiac-resynchronisation-therapy-after-percutaneous-mitral-annuloplasty
#20
Janice Swampillai
Percutaneous approaches to reduce mitral regurgitation in ischemic cardiomyopathy have stirred interest recently. Patients with ischemic cardiomyopathy and functional mitral regurgitation often meet criteria for cardiac resynchronisation therapy to improve left ventricular function as well as mitral regurgitation, and alleviate symptoms. This case shows that implantation of a pacing lead in the coronary sinus to restore synchronous left and right ventricular contraction is feasible, despite the presence of a remodeling device in the coronary sinus...
May 16, 2016: World Journal of Clinical Cases
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