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Angiomyolipoma

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https://www.readbyqxmd.com/read/28216945/ex-vivo-partial-nephrectomy-after-living-donor-nephrectomy-surgical-technique-for-expanding-kidney-donor-pool
#1
Yaw A Nyame, Paurush Babbar, Ahmed A Aboumohamed, Ryan L Mori, Stuart M Flechner, Charles S Modlin
Renal transplantation has profound improvements in mortality, morbidity, and overall quality of life compared to renal replacement therapy. This report aims to illustrate the use of ex-vivo partial nephrectomy in a patient with a renal angiomyolipoma prior to living donor transplantation. The surgical outcomes of the donor nephrectomy and recipient transplantation are reported with 2 years of follow-up. Both the donor and recipient are healthy and without any significant comorbidities. In conclusion, urologic techniques such as partial nephrectomy can be used to expand the living donor pool in carefully selected and well informed transplant recipients...
January 2017: Urology Annals
https://www.readbyqxmd.com/read/28202487/migrated-hem-o-lok-clips-in-the-ureter-a-rare-cause-of-recurrent-urinary-tract-infection
#2
Prashant Shrivastava, Brusabhanu Nayak, Prabhjot Singh
Erosion of surgical materials into the adjacent organs following surgical procedures is a rare complication. Migrations of these surgical materials into the urinary tract like pelvicalyceal system, ureter and bladder have been reported following various urological procedures. We present a case of migrated Hem-o-Lok clips into the ureter following a laparoscopic partial nephrectomy for angiomyolipoma of the left kidney presented with recurrent urinary tract infection. The case was managed with ureteroscopic removal of clips...
February 15, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28202028/management-of-everolimus-associated-adverse-events-in-patients-with-tuberous-sclerosis-complex-a-practical-guide
#3
REVIEW
Mark Davies, Anurag Saxena, John C Kingswood
Tuberous sclerosis complex (TSC) is a genetic disorder characterised by highly variable comorbid dysfunction and subsequent morbidity. The mTOR inhibitor everolimus is indicated for the treatment of adult TSC patients with renal angiomyolipomas (AMLs) and for subependymal giant astrocytoma (SEGA) in both adults and children, based on data from the EXIST-1 and EXIST-2 trials. However, due to the historical predominance of everolimus in the oncology setting, some physicians who treat TSC patients may be unfamiliar with everolimus-associated adverse events (AEs) and appropriate management strategies...
February 15, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/28197035/giant-renal-angiomyolipoma-masquerading-as-a-wilms-tumor
#4
Anjan Kumar Dhua, Abhishek Ranjan, Sandeep Agarwala, Veereshwar Bhatnagar, Sandeep R Mathur, Kandasamy Devasenathipathy
Renal Angiomyolipoma (AML) is not commonly seen in the pediatric age group other than patients of tuberous sclerosis where in they can have renal AMLs within the first decade with bilateral in involvement. Diagnosis of renal AML can generally be made by the current radiological modalities in the appropriate clinical setting, but it can be mistaken for other tumors when it is large and has low-fat content. Herein we report a case of giant renal AML that was initially misdiagnosed as a Wilms tumor in a 12-year-old girl...
January 2017: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/28188380/spontaneous-rupture-of-angiomyolipoma-of-the-kidney
#5
Friedrich C Prischl, Peter Spöttl
No abstract text is available yet for this article.
February 10, 2017: Wiener Klinische Wochenschrift
https://www.readbyqxmd.com/read/28177188/management-of-hepatic-angiomyolipoma-a-systematic-review
#6
Anne J Klompenhouwer, Danielle Verver, Shiromani Janki, Wichor M Bramer, Michail Doukas, Roy S Dwarkasing, Robert A de Man, Jan N M IJzermans
BACKGROUND & AIMS: Hepatic Angiomyolipoma (HAML) is a rare mesenchymal liver tumor assumed to be predominantly benign, although incidental cases with malignant behavior such as invasive growth, recurrence after resection and metastases have been reported. The aim of this systematic review was to assess the biological behavior, estimate the risk of HAML related mortality and recommend on a justifiable management strategy. METHODS: We performed a systematic literature search in Embase, Medline, Web-of-Science, Scopus, Pubmed Publisher, Cochrane and Google Scholar...
February 8, 2017: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/28176962/renal-angiomyolipoma-in-pregnancy-surgical-management-with-fetal-preservation-approach-in-a-developing-setting
#7
Fred O Ugwumba, Emeka F Nnakenyi, Okechukwu C Okafor, Augustine C Onuh, Paschalina C Ezechukwu, Sunday Urube
Renal angiomyolipomas (RAML) are uncommon benign renal tumours that are associated with a tendency to rupture resulting in sometimes-torrential retroperitoneal hemorrhage as the Wunderlich syndrome or as severe potentially exsanguinating hematuria. When hemorrhage from RAML occurs in pregnancy it presents a unique challenge requiring timely and appropriately adapted intervention with the goal of preventing fatality, preserving renal function as well as preventing fetal loss if possible. We report the management of severe bleeding from RAML in pregnancy and highlight the need to adopt a management strategy that suits the practice environment and offers the patient standard and enduring care...
October 24, 2016: Clinics and Practice
https://www.readbyqxmd.com/read/28174407/-operation-for-intracardiac-angiomyolipoma-report-of-a-case
#8
Hitoshi Endo, Makoto Ohno, Toshiya Kobayashi
Primary tumors of the heart are rare. In the literature operations for heart tumors account for 0.3% of all cardiac surgical procedures. We report a very rare case of primary cardiac angiomyolipoma. A 39-years-old man was admitted with chest discomfort. A mass was detected in the left ventricular myocardium by enhanced chest computed tomography. We performed resection of the intramyocardial tumor under cardiopulmonary bypass. Pathologic examination revealed a 4×3×3 cm, dome-shaped, solid tumor composed of a mixture of blood vessels, smooth muscle, and fat tissue...
February 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28167283/pre-operative-renal-artery-embolization-and-suprarenal-ivc-filter-placement-for-prevention-of-fat-embolization-in-renal-angiomyolipoma-with-venous-extension
#9
Joshua Cornman-Homonoff, David Li, Marc Schiffman
Though generally considered benign, angiomyolipomas can invade through the renal vein into the inferior vena cava, putting patients at risk of catastrophic pulmonary fat embolization. Venous invasion is thus an indication for surgical resection but is thought to increase the risk of adverse operative outcomes including intraoperative hemorrhage and embolization of fat and/or tumor thrombus. We report a novel approach to mitigating these complications illustrated in the case of a 43-year-old woman with IVC-invasive renal AML who underwent successful radical nephrectomy after concurrent pre-operative renal artery embolization and placement of a retrievable suprarenal IVC filter...
January 26, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/28152270/challenge-of-fna-diagnosis-of-angiomyolipoma-a-study-of-33-cases
#10
Haijun Zhou, Ming Guo, Yun Gong
BACKGROUND: Angiomyolipoma (AML), typically composed of smooth muscle, vessels, and fat, is generally a benign tumor in the kidneys. However, it occasionally occurs in extrarenal sites and behaves like a malignant tumor. AML is uncommonly encountered in fine-needle aspiration (FNA) samples and can cause diagnostic difficulty. METHODS: We searched our pathology database for FNA cases diagnosed between 2003 and 2015 that were subsequently confirmed to be AML in the same lesion by surgical pathologic evaluation...
February 2, 2017: Cancer
https://www.readbyqxmd.com/read/28143811/lipomatous-tumours-in-adrenal-gland-who-updates-and-clinical-implications
#11
Alfred Lam
Adrenal lipomatous tumour is a group of adrenal tumours with a significant component of adipose tissue. According to the current World Health Organization (WHO) classification of tumours of endocrine organs, adrenal myelolipoma is the only entity amongst the group of tumours being described. In the literature, other more recently documented adrenal lipomatous tumours included 24 lipomas, 32 teratomas and 16 angiomyolipomas. Rare fatty tumours of the adrenal gland comprised liposarcoma, hibernoma, adrenocortical tumours with fat component and rare adrenal tumours with fat component...
January 31, 2017: Endocrine-related Cancer
https://www.readbyqxmd.com/read/28138408/kidney-ultrasound-what-is-important-for-a-urologist
#12
REVIEW
Tomasz Szopiński, Elżbieta Keller, František Záťura
Kidney ultrasound is one of the basic procedures in the practice of a urologist. Apart from the location and the size, description of renal morphology should contain the thickness of the anterior lip parenchyma in a transverse section and the location of possible narrowings. Uneven outline of the kidney is a sign of past inflammatory conditions. In the case of the pelvicalyceal system dilation, it is advised to specify the dimensions of the pelvis and calyces. Convex shape of the calyces proves elevated pressure within the pelvicalyceal system...
December 2016: Journal of Ultrasonography
https://www.readbyqxmd.com/read/28133292/-a-case-of-angiomyolipoma-occurring-in-the-mesentery-of-the-transverse-colon-and-treated-using-laparoscopic-excision
#13
Masashi Inoue, Masahiro Tanemura, Nobutaka Hatanaka, Tatsuya Miyamoto, Shingo Seo, Megumi Yamaguchi, Toshihiro Misumi, Wataru Shimizu, Toshimitsu Irei, Takashi Onoe, Takahisa Suzuki, Takeshi Sudo, Yosuke Shimizu, Takao Hinoi, Hirotaka Tashiro
A 65-year-old woman had received chemotherapy for malignant lymphoma since 2011. After the 8th course, computed tomography revealed the disappearance of lymph node metastasis, except for 22mm of the mass located on the tail side of the antrum. MRI showed a low intensity mass on the T1 and T2-weighted images. FDG-PET did not show abnormal uptake in the tumor. EUS-FNA did not reveal a definitive diagnosis. We performed a laparotomy for diagnosis and treatment. Intraoperative findings showed that the tumor occurred in the mesentery of the transverse colon...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28130580/-what-can-should-be-treated-in-kidney-tumors-and-when
#14
C M Sommer, D F Vollherbst, G M Richter, H U Kauczor, P L Pereira
CLINICAL/METHODICAL ISSUE: In the treatment of localized renal cell carcinoma, the lack of randomization in controlled trials on thermal ablation is a major limitation. The latter leads to significant study bias and it ultimately remains unclear whether the improved overall survival in favor of partial nephrectomy can actually be attributed to the treatment method. STANDARD RADIOLOGICAL METHODS: For T1a (≤4 cm) renal cell carcinoma without lymph node and distant metastases, excellent technical and clinical results have been described after imaging-guided radiofrequency ablation and cryoablation...
February 2017: Der Radiologe
https://www.readbyqxmd.com/read/28123735/lipomatous-angiomyofibroblastoma-of-the-vulva-a-case-report-and-review-of-the-literature
#15
Susumu Matsukuma, Ayano Koga, Ryohei Suematsu, Hiroaki Takeo, Kimiya Sato
Lipomatous angiomyofibroblastoma is extremely rare, with only 16 cases reported to date. We herein describe an additional case arising in the left vulvar region of a 49-year-old woman. The resected 5.3-cm yellowish tumor predominantly consisted of fat cells (85% of the tumor), together with medium- and small-sized vessels, multifocal fibrotic areas and pseudoangiomatous spaces. Spindle, rounded, and/or epithelioid tumor cells proliferated in a nest and/or cord-like pattern, or singly within perivascular fibrous tissues and between fat cells...
January 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28122404/clinico-pathological-correlation-of-hepatic-angiomyolipoma-a-series-of-23-resection-cases
#16
Dong Hwan Jung, Shin Hwang, Seung Mo Hong, Ki Hun Kim, Chul Soo Ahn, Deok Bog Moon, Abdulwahab A Alshahrani, Sung Gyu Lee
BACKGROUND: Angiomyolipomas are rare neoplasms of mesenchymal origin and are derived from perivascular epithelioid cells. They usually develop in the kidney and rarely in the liver. Due to their rarity, most hepatic angiomyolipomas have been misinterpreted as hepatocellular carcinoma (HCC) or other hypervascular liver tumours on imaging studies. We aimed to assess the clinico-pathological correlation of hepatic angiomyolipoma. METHODS: We identified 23 patients with hepatic angiomyolipoma through an institutional database search...
January 25, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28112545/outcomes-of-angioembolization-and-nephrectomy-for-renal-angiomyolipoma-associated-with-tuberous-sclerosis-complex-a-real-world-us-national-study
#17
Peter Sun, Jamae Liu, Hearns Charles, John Hulbert, John Bissler
OBJECTIVE: To examine outcomes of clinical procedures for renal angiomyolipoma associated with tuberous sclerosis complex (TSC) based on US national health claims databases. METHODS: This retrospective cohort study selected two cohorts of TSC patients, who underwent either embolization or nephrectomy (either partial or complete) for renal angiomyolipoma in years from 2000 through 2011. Based on claims diagnosis codes, we estimated the prevalence rates of 10 angiomyolipoma-related conditions and 50 embolization- or nephrectomy-related conditions in the pre- and post-baseline periods respectively, and made cross-year and cross-period comparison of these rates with repeated measures analysis methods...
January 23, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28092822/combination-of-everolimus-with-sorafenib-for-solid-renal-tumors-in-tsc2-mice-is-superior-to-everolimus-alone
#18
Jian Yang, Paulina A Samsel, Kalin Narov, Ashley Jones, Daniel Gallacher, John Gallacher, Julian R Sampson, Ming Hong Shen
Tuberous sclerosis (TSC) is an inherited tumor syndrome caused by mutations in TSC1 or TSC2 that lead to aberrant activation of mTOR and development of tumors in multiple organs including the kidneys. The mTOR inhibitors rapamycin and everolimus (rapalogs) have demonstrated clinical efficacy in treating TSC-associated tumors including renal angiomyolipomas. However, tumor responses are usually only partial, and regrowth occurs after drug withdrawal. TSC-associated tumors are highly vascular, and TSC patients with renal angiomyolipomas have elevated levels of circulating vascular endothelial growth factor (VEGF) A and VEGFD...
February 2017: Neoplasia: An International Journal for Oncology Research
https://www.readbyqxmd.com/read/28087475/immunohistochemical-approach-for-the-diagnosis-of-a-liver-mass-on-small-biopsy-specimens
#19
Won-Tak Choi, Rageshree Ramachandran, Sanjay Kakar
Well-differentiated hepatocellular carcinoma (HCC) shares overlapping histological features with benign hepatocellular lesions, including hepatocellular adenoma (HCA) and focal nodular hyperplasia (FNH) in non-cirrhotic liver, and with high-grade dysplastic nodule (HGDN) in cirrhotic liver. Several metastatic tumors, such as neuroendocrine tumor, renal cell carcinoma, adrenocortical carcinoma, melanoma, and epithelioid angiomyolipoma, can be indistinguishable from HCC on histologic grounds. Since this distinction has important therapeutic implications, judicious use of immunohistochemical markers plays an important role in establishing an accurate diagnosis, especially when limited material of tumor is available on cell block or a small core biopsy...
January 10, 2017: Human Pathology
https://www.readbyqxmd.com/read/28068796/partial-nephrectomy-for-presumed-renal-cell-carcinoma-incidence-predictors-and-perioperative-outcomes-of-benign-lesions
#20
Tyler M Bauman, Aaron M Potretzke, Alec J Wright, Brent A Knight, Joel M Vetter, Robert Sherburne Figenshau
BACKGROUND: The aim of this study was to investigate the incidence of benign histology after partial nephrectomy (PN) in patients with presumed malignancy from preoperative imaging. Furthermore, preoperative predictors of benign lesions and perioperative outcomes were also assessed. METHODS: A series of patients undergoing PN for renal masses was identified using a prospectively maintained database. Patients were excluded for known genetic conditions, if more than one renal mass was resected, or if standard preoperative imaging was not suspicious for renal-cell carcinoma (RCC)...
February 3, 2017: Journal of Endourology
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