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https://www.readbyqxmd.com/read/28641899/obstructive-sleep-apnoea-in-craniofacial-microsomia-analysis-of-755-patients
#1
C J J M Caron, B I Pluijmers, B D P J Maas, Y P Klazen, E S Katz, F Abel, M P van der Schroeff, I M J Mathijssen, D J Dunaway, C Mills, D S Gill, N Bulstrode, B L Padwa, E B Wolvius, K F M Joosten, M J Koudstaal
A retrospective cohort study was set up to analyse the prevalence and treatment of obstructive sleep apnoea (OSA) in relation to the severity of the deformity in patients with craniofacial microsomia (CFM). This study included a population of 755 patients with CFM from three craniofacial centres. Medical charts were reviewed for severity of the deformity, types of breathing difficulty, age at which breathing difficulty first presented, treatment for OSA, and treatment outcome. In total, 133 patients (17.6%) were diagnosed with OSA...
June 19, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28640938/obstructive-sleep-apnoea-and-polycystic-ovary-syndrome-a-comprehensive-review-of-clinical-interactions-and-underlying-pathophysiology
#2
REVIEW
Hassan Kahal, Ioannis Kyrou, Abd A Tahrani, Harpal S Randeva
Polycystic ovary syndrome (PCOS) is the most prevalent endocrine disorder in women of reproductive age. PCOS is associated with multiple co-morbidities including, obesity, insulin resistance and type 2 diabetes, as well as mood disorders and impaired quality of life (QoL). Obstructive sleep apnoea (OSA) is also a common medical condition that is often undiagnosed, particularly in women. OSA is associated with a similar spectrum of comorbidities to that observed in PCOS, including manifestations of the metabolic syndrome and impaired QoL, whilst obesity frequently constitutes a common denominator in the pathophysiology of both OSA and PCOS...
June 22, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28635199/a-case-of-obstructive-sleep-apnea-syndrome-associated-with-floppy-eyelid-syndrome-positive-effect-of-cpap-therapy
#3
Roberto Porta, Laura Comini, Luca Barbano, Luca Bianchi, Michele Vitacca
The obstructive sleep apnoea syndrome (OSAS) may be associated with several eyes disorders, among which the most common is the floppy eyelid syndrome (FES). We intended to highlight the association between OSAS and FES and evaluate the effect of FES treatment with Continuous Positive Airway Pressure (CPAP). A 50-year patient with a 10-year history of snoring, sleep fragmentation and daytime sleepiness associated with several comorbidities has been studied. For six months, several ocular symptoms were present, particularly on waking up in the morning...
May 18, 2017: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
https://www.readbyqxmd.com/read/28635195/a-study-to-estimate-prevalence-and-risk-factors-of-obstructive-sleep-apnoea-syndrome-in-a-semi-urban-indian-population
#4
Abhijeet Singh, Rajendra Prasad, Rajiv Garg, Surya Kant, Giridhar B Hosmane, Abhisek Dubey, Abhisek Agarwal, Ram Kishun Verma
Obstructive Sleep Apnea Syndrome (OSAS) has been recognised as a major cause of morbidity and mortality in developing countries like India. There is still a paucity of Indian studies regarding the prevalence of OSAS. The current single centre prospective cross-sectional study was undertaken to know prevalence estimates for key symptoms and features that can indicate the presence of OSAS in an Indian population. A survey was conducted on subjects with age groups ≥ 25 years at King George's Medical University, Lucknow, Uttar Pradesh, India from August 2009 to July 2011...
May 18, 2017: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
https://www.readbyqxmd.com/read/28633578/the-imperative-to-screen-for-obstructive-sleep-apnoea-in-people-with-schizophrenia
#5
Stephen Parker, Bradford Johnston, Abigail Lane, Frances Dark, Dan Siskind
No abstract text is available yet for this article.
July 2017: Australian and New Zealand Journal of Psychiatry
https://www.readbyqxmd.com/read/28625122/a-ten-year-review-of-chronic-cor-pulmonale-secondary-to-respiratory-diseases-in-ghana
#6
Collins Oduro-Boatey, Della Adzosii
Chronic cor pulmonale is defined as right ventricular failure secondary to pulmonary hypertension. Our study reviewed all cases of chronic cor pulmonale secondary to respiratory diseases in a ten-year period (2004-20014) in the Department of Child Health, Korle-Bu Teaching Hospital, Ghana. Nine cases of chronic cor pulmonale were recorded during the period. The age range was 1-9 years (average age = 3 years). Obstructive sleep apnoea secondary to adenoid hypertrophy was the commonest cause of pulmonary hypertension...
January 1, 2017: Tropical Doctor
https://www.readbyqxmd.com/read/28623043/nasal-airway-evaluation-in-obstructive-sleep-apnoea-patients-volumetric-tomography-and-endoscopic-findings
#7
M M Rodrigues, M F R Gabrielli, O A Garcia Junior, V A Pereira Filho, L A Passeri
Obstructive sleep apnoea (OSA) results from the recurrent collapse of the upper airway during sleep. Nasal abnormalities influence the stability of the pharynx. The aim of this study was to evaluate the volumetric and anatomical changes of the nasal cavity in patients with OSA. The Nasal Obstruction Symptom Evaluation (NOSE) scale was used to grade nasal obstruction. Sleep-related breathing disorders were evaluated by polysomnography. The nasal airway volume was obtained from computed tomography scans through volumetric reconstruction of the nasal airway...
June 13, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28619958/monocytes-inhibit-nk-activity-via-tgf-%C3%AE-in-patients-with-obstructive-sleep-apnoea
#8
Enrique Hernández-Jiménez, Carolina Cubillos-Zapata, Victor Toledano, Rebeca Pérez de Diego, Isabel Fernández-Navarro, Raquel Casitas, Carlos Carpio, Jose Casas-Martín, Jaime Valentín, Anibal Varela-Serrano, Jose Avendaño-Ortiz, Enrique Alvarez, Luis A Aguirre, Antonio Pérez-Martínez, Maria P De Miguel, Cristobal Belda-Iniesta, Francisco García-Río, Eduardo López-Collazo
Obstructive sleep apnoea (OSA) is associated with cancer incidence and mortality. The contribution of the immune system appears to be crucial; however, the potential role of monocytes and natural killer (NK) cells remains unclear.Quantitative reverse transcriptase PCR, flow cytometry and in vitro assays were used to analyse the phenotype and immune response activity in 92 patients with OSA (60 recently diagnosed untreated patients and 32 patients after 6 months of treatment with continuous positive airway pressure (CPAP)) and 29 healthy volunteers (HV)...
June 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28619952/cardiometabolic-correlates-of-sleep-disordered-breathing-in-andean-highlanders
#9
Luu V Pham, Catherine H Miele, Noah G Schwartz, Rafael S Arias, Adi Rattner, Robert H Gilman, J Jaime Miranda, Vsevolod Y Polotsky, William Checkley, Alan R Schwartz
Associations between sleep disordered breathing (SDB) and cardiometabolic outcomes have not been examined in highlanders.We performed nocturnal polygraphy in Peruvian highlanders (3825 m). Multivariable linear regression models examined associations between SDB metrics and haemoglobin, glucose tolerance (haemoglobin A1c (HbA1c)), fasting glucose, homeostatic model-based assessments of insulin resistance and β-cell function (HOMA-IR and HOMA-β, respectively), blood pressure, and lipids, while adjusting for age, sex, body mass index (BMI) and wake oxygenation...
June 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28618108/chronic-respiratory-disease-in-the-regional-and-remote-population-of-the-northern-territory-top-end-a-perspective-from-the-specialist-respiratory-outreach-service
#10
Anuk Kruavit, Melissa Fox, Rebecca Pearson, Subash Heraganahally
OBJECTIVE: To study the demographic, rates and types of chronic respiratory conditions in Indigenous and non-Indigenous patients in regional and remote communities of Northern Territory Top End, who were referred to the specialist respiratory outreach service. DESIGN: A retrospective, observational study over a 2 years period. SETTING: Remote community health clinics within the Northern Territory Top End visited by the specialist respiratory outreach team...
June 15, 2017: Australian Journal of Rural Health
https://www.readbyqxmd.com/read/28610436/obstructive-sleep-apnoea-in-diabetes-does-it-matter
#11
Abd A Tahrani
Obstructive sleep apnoea (OSA) is very common in patients with Type 2 diabetes (T2D), which is not surprising considering that obesity is a common risk factor for both conditions. In general population studies, OSA has been shown to be associated with several comorbidities including increased risk of road traffic accidents, T2D, hypertension and lack of nocturnal dipping of blood pressure, hyperlipidaemia, increased inflammation, increased risk of cardiovascular disease and mortality, increased risk of atrial fibrillation, worse quality of life, and erectile dysfunction...
June 1, 2017: Diabetes & Vascular Disease Research
https://www.readbyqxmd.com/read/28606851/cardiorespiratory-action-of-opioid-tachykinin-agonist-peptide-hybrid-in-anaesthetized-rats-transduction-pathways
#12
Piotr Wojciechowski, Małgorzata Szereda-Przestaszewska, Andrzej Wojciech Lipkowski
AWL3106 composed of opioid (dermorphin) and tachykinin (substance P7-11) pharmacophores is a new compound with high analgesic potency and markedly reduced ability to induce tolerance and dependence. The present study aimed to determine the respiratory and cardiovascular responses evoked by this peptide in urethane-chloralose anaesthetized, spontaneously breathing rats in the presence or absence of vagal connection. Intravenous injection of AWL3106 at a dose of 0.3μmol/kg in intact rats resulted in apnoea lasting 5...
June 9, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28604833/chest-mri-under-pulsatile-flow-ventilation-a-new-promising-technique
#13
Catherine Beigelman-Aubry, Nicolas Peguret, Matthias Stuber, Jean Delacoste, Bastien Belmondo, Alban Lovis, Julien Simons, Olivier Long, Kathleen Grant, Gregoire Berchier, Chantal Rohner, Gabriele Bonanno, Simone Coppo, Juerg Schwitter, Mahmut Ozsahin, Salah Qanadli, Reto Meuli, Jean Bourhis
OBJECTIVES: Magnetic resonance imaging (MRI) of the chest has long suffered from its sensitivity to respiratory and cardiac motion with an intrinsically low signal to noise ratio and a limited spatial resolution. The purpose of this study was to perform chest MRI under an adapted non invasive pulsatile flow ventilation system (high frequency percussive ventilation, HFPV®) allowing breath hold durations 10 to 15 times longer than other existing systems. METHODS: One volunteer and one patient known for a thymic lesion underwent a chest MRI under ventilation percussion technique (VP-MR)...
2017: PloS One
https://www.readbyqxmd.com/read/28600583/relation-of-cardiac-arrhythmias-to-hypoxic-time-and-lowest-oxygen-saturation-in-patients-with-obstructive-sleep-apnoea-in-an-asian-context-a-singapore-sleep-centre-study
#14
Adele Cw Ng, Wei Li Neo, Mahalakshmi Rangabashyam, Ying Hao, Kah Leng Ho, Song Tar Toh
No abstract text is available yet for this article.
May 2017: Annals of the Academy of Medicine, Singapore
https://www.readbyqxmd.com/read/28597190/the-prevalence-of-rem-related-obstructive-sleep-apnoea-is-reduced-by-the-aasm-2012-hypopnoea-criteria
#15
Brett Duce, Antti Kulkas, Christian Langton, Juha Töyräs, Craig Hukins
PURPOSE: The variations in reported prevalence of rapid eye movement-related obstructive sleep apnoea (REM-OSA) have been attributed to different definitions, although the effect of hypopnoea criteria has not been previously investigated. METHODS: Within this retrospective study, 134 of 382 consecutive patients undertaking polysomnography (PSG) for the suspicion of OSA met the inclusion criteria. PSGs were scored using both the 2007 AASM recommended hypopnoea criteria (AASM2007Rec) and the 2012 AASM recommended hypopnoea criteria (AASM2012Rec)...
June 9, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28596432/obstructive-sleep-apnoea-and-related-comorbidities-in-incident-idiopathic-pulmonary-fibrosis
#16
Thomas Gille, Morgane Didier, Marouane Boubaya, Loris Moya, Angela Sutton, Zohra Carton, Fanny Baran-Marszak, Danielle Sadoun-Danino, Dominique Israël-Biet, Vincent Cottin, Frederic Gagnadoux, Bruno Crestani, Marie-Pia d'Ortho, Pierre-Yves Brillet, Dominique Valeyre, Hilario Nunes, Carole Planès
The objectives of this prospective study were: 1) to determine the prevalence and determinants of obstructive sleep apnoea (OSA) in patients with newly diagnosed idiopathic pulmonary fibrosis (IPF); 2) to determine whether OSA was associated with cardiovascular disease (CVD) as well as increased oxidative stress and levels of IPF biomarkers in the blood.A group of 45 patients with newly diagnosed IPF attended polysomnography. The prevalence of CVD and the severity of coronary artery calcification were investigated by high-resolution computed tomography...
June 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28596431/nonalcoholic-fatty-liver-disease-in-chronic-obstructive-pulmonary-disease
#17
Damien Viglino, Ingrid Jullian-Desayes, Mélanie Minoves, Judith Aron-Wisnewsky, Vincent Leroy, Jean-Pierre Zarski, Renaud Tamisier, Marie Joyeux-Faure, Jean-Louis Pépin
Nonalcoholic fatty liver disease (NAFLD) is independently linked to cardiometabolic morbidity and mortality. Low-grade inflammation, oxidative stress and ectopic fat, common features of chronic obstructive pulmonary disease (COPD), might contribute to the development of NAFLD.We aimed to investigate the prevalence of NAFLD and to evaluate the relationship between various types of liver damage and COPD severity, comorbidities and circulating inflammatory cytokines. Validated noninvasive tests (FibroMax: SteatoTest, NashTest and FibroTest) were used to assess steatosis, nonalcoholic steatohepatitis (NASH) and liver fibrosis...
June 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28594570/obstructive-sleep-apnoea-and-retinopathy-in-patients-with-type-2-diabetes-a-longitudinal-study
#18
Quratul A Altaf, Paul Dodson, Asad Ali, Neil T Raymond, Helen Wharton, Hannah Fellows, Rachel Hampshire-Bancroft, Mirriam Shah, Emma Shepherd, Jamili Miah, Anthony H Barnett, Abd A Tahrani
AIMS: To assess the relationship between obstructive sleep apnoea (OSA) and diabetic retinopathy (DR) in patients with type 2 diabetes (T2D) and to assess whether OSA is associated with its progression). METHODS: A longitudinal study from diabetes clinics in two UK hospitals was conducted. Patients known to have any respiratory disorder (including OSA) were excluded. DR was assessed using 2x45degrees retinal images per eye. OSA was assessed using a home-based, multi-channel cardiorespiratory device...
June 8, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28589663/co-morbid-osa-and-insomnia-increases-depression-prevalence-and-severity-in-men
#19
Carol J Lang, Sarah L Appleton, Andrew Vakulin, R Doug McEvoy, Gary A Wittert, Sean A Martin, Peter G Catcheside, Nicholas A Antic, Leon Lack, Robert J Adams
BACKGROUND AND OBJECTIVE: Obstructive sleep apnoea (OSA) and insomnia coexist in clinical populations but prevalence in the community and risk factors remain largely unknown. We examined the prevalence and profile of previously undiagnosed co-morbid OSA and insomnia symptoms (COMISA) in community-dwelling men. METHODS: Men (n = 700, aged 58.5 ± 11.0 (mean ± SD) years) without a prior diagnosis of OSA completed full at-home unattended polysomnography, the Pittsburgh Sleep Quality Index and 36-item short form (SF-36) survey (2007-2012)...
June 7, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28584940/drug-induced-sedation-endoscopy-dise-classification-systems-a-systematic-review-and-meta-analysis
#20
REVIEW
Esuabom Dijemeni, Gabriele D'Amone, Israel Gbati
PURPOSE: Drug-induced sedation endoscopy (DISE) classification systems have been used to assess anatomical findings on upper airway obstruction, and decide and plan surgical treatments and act as a predictor for surgical treatment outcome for obstructive sleep apnoea management. The first objective is to identify if there is a universally accepted DISE grading and classification system for analysing DISE findings. The second objective is to identify if there is one DISE grading and classification treatment planning framework for deciding appropriate surgical treatment for obstructive sleep apnoea (OSA)...
June 6, 2017: Sleep & Breathing, Schlaf & Atmung
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