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https://www.readbyqxmd.com/read/28441072/pro-tumor-activities-of-macrohpages-in-the-progression-of-melanoma
#1
Huafeng Wang, Luhong Yang, Dong Wang, Qi Zhang, Lijuan Zhang
Macrophages are located in essentially all tissues due to their "janitor" function. Macrophages can exert either anti- or pro-tumor activities depending upon the specific tumor microenvironment they inhabit. Substantial evidence indicates that macrophages, owing to their plasticity, can be reeducated to adopt a protumoral phenotype within a tumor microenvironment through the help of growth factors in the microenvironment and intercellular interactions. As the lethality of malignant melanoma is due to its aggressive capacity for metastasis and resistance to therapy, considerable effort has gone toward treatment of metastatic melanoma...
April 25, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28408876/effects-of-age-related-macular-degeneration-on-postural-sway
#2
Hortense Chatard, Laure Tepenier, Olivier Jankowski, Antoine Aussems, Alain Allieta, Talal Beydoun, Sawsen Salah, Maria P Bucci
Purpose: To compare the impact of unilateral vs. bilateral age-related macular degeneration (AMD) on postural sway, and the influence of different visual conditions. The hypothesis of our study was that the impact of AMD will be different between unilateral and bilateral AMD subjects compared to age-matched healthy elderly. Methods: Postural stability was measured with a platform (TechnoConcept®) in 10 elderly unilateral AMD subjects (mean age: 71.1 ± 4.6 years), 10 elderly bilateral AMD subjects (mean age: 70...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28398915/noise-in-the-neonatal-intensive-care-unit-what-does-the-evidence-tell-us
#3
Sharon G Casavant, Katherine Bernier, Sheena Andrews, Allison Bourgoin
BACKGROUND: In 2014, more than 10% of all births in the United States were preterm (born at <37-weeks' gestation). These high-risk infants will often spend weeks to months within the neonatal intensive care unit (NICU), where noise levels can easily reach 120 decibels adjusted (dBA) on a regular and sometimes consistent basis. The American Academy of Pediatrics recommends that NICU sound levels remain below 45 dBA to promote optimal growth and development. PURPOSE: The purpose of this evidence-based brief is to critically appraise the literature concerning preterm infant response to noise within the NICU as well as the use of noise interventions to improve health outcomes for the vulnerable preterm infant population...
April 7, 2017: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/28390603/velopharyngeal-insufficiency-managed-by-autologous-fat-grafting-in-patients-with-aberrant-courses-of-internal-carotid-arteries
#4
Emilie Bois, Charlotte Celerier, Kahina Belhous, Michel Maulet, Nicolas Leboulanger, Noël Garabedian, Françoise Denoyelle
INTRODUCTION: Velopharyngeal insufficiency (VPI) is usually managed, besides speech therapy, by performing a velopharyngoplasty. An alternative approach is autologous fat grafting (AFG) of the posterior pharyngeal wall. About 5% of the population has internal carotid arteries (ICA) with an aberrant course. This anatomic variation can be responsible for surgical difficulties while when performing a velopharyngoplasty, and therefore lead surgeons to only consider a speech reeducation of VPI...
May 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28352637/neurostimulation-for-fecal-incontinence-after-correction-of-repair-of-imperforate-anus
#5
Alexandre Bougie, Nathalie McFadden, Sandeep Mayer, Michel Lebel, Ghislain Devroede
We are reporting the case of a 32-year-old female who had suffered from fecal incontinence (FI). She was born with an imperforate anus and a recto-vaginal fistula; she underwent repair at 6 mo of age. At 29 years of age, she was still fecally incontinent despite extensive pelvic floor reeducation. A magnetic resonance imaging and an anal electromyography were performed. Because her symptoms were considered to be probably due to extra-sphincteric implantation of the neo-anus, a redo was performed of the recto-neo-anal intra-sphincteric anastomosis...
March 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/28236212/probing-the-bi-directional-interaction-between-microglia-and-gliomas-in-a-tumor-microenvironment-on-a-microdevice
#6
Rui Gu, Xu Zhang, Ge Zhang, Tingting Tao, Haibo Yu, Lianqing Liu, Ying Dou, Aiping Li, Jianhua Qin
It has been proven that microglia are involved in both early and late stages of glioma progression and contribute substantially to the tumor mass of gliomas. Because no appropriate in vitro or in vivo investigative approach is available, the dynamic interaction between microglia and gliomas during tumor formation remains unclear. In this study, three types of microfluidic assay were developed to examine the outcomes of the dynamic interaction between microglia and gliomas. Co-migration assay and two-dimensional cell co-culture assay have been used to show that microglial BV-2 cells migrate toward C6 glioma cells and inhibit tumor growth during the early stage of tumorigenesis...
February 24, 2017: Neurochemical Research
https://www.readbyqxmd.com/read/28157086/professional-activities-of-professor-kazimiera-milanowska-in-the-field-of-rehabilitation
#7
Maciej Łuczak, Mateusz Milanowski
Professor Kazimiera Milanowska is a rehabilitation physician and academic scholar of international renown. She has extensive expert knowledge and scientific achievements in the fields of medical rehabilitation and physical culture sciences. The aim of the present biographical study was to present the development of Prof. Kazimiera Milanowska's career. As Head of the Rehabilitation Department at the Medical Academy in Poznań, she delivered lectures on the clinical foundations of rehabilitation and theory and philosophy of modern rehabilitation as well as numerous courses on methods of musculoskeletal compensation and adaptation, muscle reeducation, and rehabilitation following peripheral neuron injury...
May 5, 2016: Ortopedia, Traumatologia, Rehabilitacja
https://www.readbyqxmd.com/read/28146141/type-1-diabetes-from-adolescence-to-adulthood-is-there-a-permanent-need-for-nutrition-education-and-reeducation
#8
Maja Baretić, Martina Matovinović Osvatić, Eva Pavić, Nada Rabađija, Valentina Uroić, Carolina Koletić, Nataša Rojnić Putarek, Ivana Pavlić Renar
BACKGROUND: The transition for type 1 diabetes patients from paediatric to adult diabetology care is challenging process for both medical team and patients. Adult diabetology usually insists on stricter goals and focuses on increased empowerment and self-care. We set to find a more practical and effective way to determine patient knowledge and skills during the transition. The aim of the study was to identify screening questions which best represent knowledge in management of type 1 diabetes and to explore the differences in the effect of a structured educational program for type 1 diabetes patient diagnosed in childhood versus adulthood...
January 31, 2017: Minerva Endocrinologica
https://www.readbyqxmd.com/read/28138421/efficacy-and-retention-of-basic-life-support-education-including-automated-external-defibrillator-usage-during-a-physical-education-period
#9
Kae Watanabe, Dalia Lopez-Colon, Jonathan J Shuster, Joseph Philip
The American Heart Association (AHA) advocates for CPR education as a requirement of secondary school curriculum. Unfortunately, many states have not adopted CPR education. Our aim was to investigate a low-cost, time effective method to educate students on Basic Life Support (BLS), including reeducation. This is a prospective, randomized study. Retention was assessed at 4 months post-initial education. Education was performed by AHA-certified providers during a 45-minute physical education class in a middle school in Florida...
March 2017: Preventive Medicine Reports
https://www.readbyqxmd.com/read/28039506/microsurgical-anatomy-of-branches-of-musculocutaneous-nerve-clinical-relevance-for-spastic-elbow-surgery
#10
C Thieffry, L Chenin, P Foulon, E Havet, J Peltier
PURPOSE: The neurotomy of musculocutaneous nerve is a treatment for patients who suffer from spastic elbow flexion when medical and reeducative treatments have failed. It consists in sectioning motor branches of musculocutaneous nerve which are destined to the biceps brachii and brachialis muscles, both being the main elbow flexor muscles. The aim of this study was to analyse the distance, where each motor branch arises from the musculocutaneous nerve to both biceps brachii and brachialis muscles, to establish precisely the localisation and length of the necessary incision to reach its branches for surgery...
December 30, 2016: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/27903941/prep-t1-preteen-re-education-with-parents-type-1-diabetes-feasibility-intervention-results
#11
Susan Sullivan-Bolyai, Sybil Crawford, Kim Johnson, Neesha Ramchandani, Diane Quinn, Bianca D'Alesandro, Kailyn Stern, Terry Lipman, Gail Melkus, Randi Streisand
There has been a 2% to 3% increase in Type 1 diabetes (T1D) in children below 11 years old. Preteens (9-12 years old) with T1D are often overlooked regarding future diabetes self-management (DSM) expectations because parents are still in the "driver's seat." The study purpose was to explore feasibility/ability to recruit and conduct a two-arm trial on reeducation, collaboration, and social support. One component of DSM was reviewed (hypoglycemia) with preteens (n = 22) and parents (n = 22). The experimental preteens discussed hypoglycemia management with a teen mentor and nurse educator using a human patient simulator for practice, and working collaboratively with parents...
November 2016: Journal of Family Nursing
https://www.readbyqxmd.com/read/27882044/the-importance-of-rehabilitation-concerning-upper-extremity-amputees-a-systematic-review
#12
REVIEW
Kardem Soyer, Banu Unver, Seval Tamer, Ozlem Ulger
OBJECTIVE: To evaluate and point out the importance of prosthetic rehabilitation of upper extremity. METHODS: A systematic literature search was performed to identify studies concerning prosthetic rehabilitation in upper extremity. The PRISMA Statement 2009 was used to establish the study and the methodological quality was assessed. RESULTS: The literature search identified 620 studies. Of these 620, 9 studies fulfilled the inclusion criteria and were included for data extraction...
September 2016: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/27818682/current-trends-in-neuromuscular-blockade-management-and-monitoring-amongst-singaporean-anaesthetists
#13
Wendy H Teoh, Thomas Ledowski, Phillip S Tseng
Introduction. This survey aimed to investigate the attitudes/practice pertaining the use, management, and monitoring of neuromuscular blockade amongst Singaporean anaesthetists. Methods. All specialist accredited anaesthetists registered with the Singapore Medical Council were invited to complete an anonymous online survey. Results. The response rate was 39.5%. Neuromuscular monitoring (NM) was used routinely by only 13.1% despite the widespread availability of monitors. 82% stated residual NMB (RNMB) was a significant risk factor for patient outcome, but only 24% believed NMB monitoring should be compulsory in all paralyzed patients...
2016: Anesthesiology Research and Practice
https://www.readbyqxmd.com/read/27787382/abuse-related-trauma-forward-medical-care-in-a-randomly-sampled-nationwide-population
#14
MULTICENTER STUDY
Cheng-Maw Ho, Chih-Hsin Lee, Jann-Yuan Wang, Po-Huang Lee, Hong-Shiee Lai, Rey-Heng Hu, Jin-Shing Chen
Abuse-related trauma remains a global health issue. However, there is paucity in nationwide reports. We aim to estimate the incidence of abuse-related trauma forward medical care and identify its characteristics and clinical course in Taiwan. Patients with trauma between 2005 and 2007 that occurred 3 months before or after a diagnosis of abuse were identified from a randomly sampled nationwide longitudinal health insurance database of 1 million beneficiaries. The patients' demographic data, injury pattern, and medical resource utilization were measured, stratified by age and sex, and compared using chi-square test...
October 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27726841/-masticatory-apparatus-disorder-how-can-rehabilitation-treatment-help
#15
Isabelle Breton-Torres, Manon Serre, Patrick Jammet, Jacques Yachouh
INTRODUCTION: The temporomandibular joint is highly adaptive and masticatory apparatus disorders (MAD) can occur when its ability to adapt is overwhelmed. Occlusal etiologies were long pinpointed as the sole culprits. However, a consensus now exists which minimizes their involvement. It is recognized that the etiology of MAD is multifactorial, combining occlusal problems, parafunctions, postural anomalies, orofacial dyspraxia and stress. MATERIALS AND METHODS: In this article, the authors review the role of physiotherapy in managing these pathologies...
September 2016: L' Orthodontie Française
https://www.readbyqxmd.com/read/27676828/contribution-of-isokinetic-in-tendinopathy-of-the-rotator-cuff-experience-of-physical-medicine-and-rehabilitation-casablanca
#16
Karima Belhaj, Soumia Meftah, Hicham Elhyaoui, Laila Mahir, Amine Tahir, Mohamed Rahmi, Mohamed Rafai, Abdelhak Garch, Mohamed Nechad, Fatima Lmidmani, Abdellatif Elfatimi
OBJECTIVE: Originally developed for the purpose of muscle strengthening, mainly for knee muscles, the isokinetic has gradually seen its scope expand to other joints, especially in muscle testing, becoming one of reference. Son methods applied to the pathology of the shoulder is relatively recent and, to date, the rules for implementing the tests and rehabilitation remain unclear. The aim of study is to define the contribution of the isokinetic evaluation in the management of shoulder tendon...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27587423/quality-improvement-intervention-to-decrease-prolonged-mechanical-ventilation-after-coronary-artery-bypass-surgery
#17
Jennifer L Hefner, Ravi S Tripathi, Erik E Abel, Michelle Farneman, Jason Galloway, Susan D Moffatt-Bruce
BACKGROUND: In 2010, the incidence of prolonged mechanical ventilation (> 24 hours) after isolated coronary artery bypass graft (CABG) surgery was 26.9% at the study site, The Ohio State University Wexner Medical Center, compared with the national like-hospital rate of 10.9%. OBJECTIVES: To use the principles of lean management to reduce the incidence of prolonged mechanical ventilation and to assess the sustainability of that reduction over time. METHODS: A multidisciplinary prolonged ventilation task force conducted a gap analysis leading to 3 interventions: (1) a standardized extubation protocol, (2) dry erase boards in patients' rooms to facilitate team communication, and (3) edits of the postoperative order set within the electronic health record...
September 2016: American Journal of Critical Care: An Official Publication, American Association of Critical-Care Nurses
https://www.readbyqxmd.com/read/27499255/-contribution-of-the-physical-and-rehabilitation-medicine-in-pediatric-plastic-surgery
#18
L Gottrand, F Devinck, V Martinot Duquennoy, P Guerreschi
Physical, non-painful processes guide the scar reshaping in children in order to prevent growth anomalies due to cutaneous shrinkage. The objective of the surgical treatment, coordinated with the reeducation care, is to improve the physical abilities of the skin, to restore the function and avoid the deformations. Reeducation uses various techniques (i.e. sensitive-motility, massage and mobilizations) with or without physical agent (water, aspiration and touch-drive technique). Posture and positioning rely on the small or major aids, from orthosis to prosthesis...
October 2016: Annales de Chirurgie Plastique et Esthétique
https://www.readbyqxmd.com/read/27437710/global-postural-reeducation-for-patients-with-musculoskeletal-conditions-a-systematic-review-of-randomized-controlled-trials
#19
Giovanni E Ferreira, Rodrigo G P Barreto, Caroline C Robinson, Rodrigo D M Plentz, Marcelo F Silva
OBJECTIVES: To systematically review randomized controlled trials that assessed the effects of Global Postural Reeducation (GPR) on patient-reported outcomes in conditions of the musculoskeletal system. METHOD: An electronic search of MEDLINE (via PubMed), EMBASE, Cochrane CENTRAL, and SciELO was performed from their inception to June 2015. Randomized controlled trials that analyzed pain and patient-reported outcomes were included in this review. The Cochrane Collaboration's Risk of Bias Tool was used to evaluate risk of bias, and the quality of evidence was rated following the GRADE approach...
April 1, 2016: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/27383347/psychological-distress-and-work-stress-in-correctional-officers-a-literature-review
#20
Cláudia de Magalhães Bezerra, Simone Gonçalves de Assis, Patricia Constantino
This article presents a review of literature based on a survey of national and international journals on psychological distress and stress in the work of correctional officers between 2000 and 2014. The databases used were the Biblioteca Virtual em Saúde, Web of Science, and Scopus, and the descriptors were psychological distress, stress and correctional officers. We analyzed 40 articles, mainly about stress. The concept of burnout appeared in several works. The United States is the country that most publishes on the subject...
June 2016: Ciência & Saúde Coletiva
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