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https://www.readbyqxmd.com/read/28811520/chronic-post-stroke-aphasia-severity-is-determined-by-fragmentation-of-residual-white-matter-networks
#1
Barbara K Marebwa, Julius Fridriksson, Grigori Yourganov, Lynda Feenaughty, Chris Rorden, Leonardo Bonilha
Many stroke survivors with aphasia in the acute period experience spontaneous recovery within the first six months after the stroke. However, approximately 30-40% sustain permanent aphasia and the factors determining incomplete recovery are unclear. Suboptimal recovery may be influenced by disruption of areas seemingly spared by the stroke due to loss of white matter connectivity and network integrity. We reconstructed individual anatomical whole-brain connectomes from 90 left hemisphere stroke survivors using diffusion MR images...
August 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28809939/a-cross-sectional-study-comparing-lateral-and-diagonal-maximum-weight-shift-in-people-with-stroke-and-healthy-controls-and-the-correlation-with-balance-gait-and-fear-of-falling
#2
Margaretha M van Dijk, Sarah Meyer, Solveig Sandstad, Evelyne Wiskerke, Rhea Thuwis, Chesny Vandekerckhove, Charlotte Myny, Nitesh Ghosh, Hilde Beyens, Eddy Dejaeger, Geert Verheyden
Impaired balance is common post stroke and can be assessed by means of force-platforms measuring center of pressure (COP) displacements during static standing, or more dynamically during lateral maximum weight shift (MWS). However, activities of daily life also include diagonal MWS and since force platforms are nowadays commercially available, investigating lateral and diagonal MWS in a clinical setting might be feasible and clinically relevant. We investigated lateral and diagonal MWS while standing in patients with stroke (PwS) and healthy controls (HC), evaluated MWS towards the affected and the non-affected side for PwS and correlated MWS with measures of balance, gait and fear of falling...
2017: PloS One
https://www.readbyqxmd.com/read/28807692/community-use-of-physical-and-occupational-therapy-after-stroke-and-risk-of-hospital-readmission
#3
Janet K Freburger, Dongmei Li, Erin P Fraher
OBJECTIVES: To determine whether receipt of therapy and number and timing of therapy visits decreased hospital readmission risk in stroke survivors discharged home. DESIGN: Retrospective cohort analysis of Medicare claims (2010-2013). SETTING: Acute care hospital and community. PARTICIPANTS: Patients hospitalized for stroke who were discharged home and survived the first 30 days (N=23,413; mean [SD] age of 77.6 [7.5] years)...
August 11, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28807138/prevalence-and-predictors-of-post-stroke-mood-disorders-a-meta-analysis-and-meta-regression-of-depression-anxiety-and-adjustment-disorder
#4
Alex J Mitchell, Bhavisha Sheth, John Gill, Motahare Yadegarfar, Brendon Stubbs, Mohammad Yadegarfar, Nick Meader
OBJECTIVE: To ascertain the prevalence and predictors of mood disorders, determined by structured clinical interviews (ICD or DSM criteria) in people after stroke. METHODS: Major electronic databases were searched from inception to June 2016 for studies involving major depression (MDD), minor depression (MnD), dysthymia, adjustment disorder, any depressive disorder (any depressive disorder) and anxiety disorders. Studies were combined using both random and fixed effects meta-analysis and results were stratified as appropriate...
July 2017: General Hospital Psychiatry
https://www.readbyqxmd.com/read/28797618/risk-factors-for-falls-in-community-stroke-survivors-a-systematic-review-and-meta-analysis
#5
REVIEW
Tianma Xu, Lindy Clemson, Kate O'Loughlin, Natasha A Lannin, Catherine Dean, Gerald Koh
OBJECTIVE: To identify the risk factors for falls in community stroke survivors. DATA SOURCES: A comprehensive search for articles indexed on MEDLINE, EMBASE, CINAHL, PsychINFO, Cochrane Library, and Web of Science databases was conducted. STUDY SELECTION: Prospective studies investigating fall risk factors in community stroke survivors were included. Reviewers in pair independently screened the articles and determined inclusion through consensus...
August 7, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28796991/epidemiology-of-intracranial-and-extracranial-large-artery-stenosis-in-a-population-based-study-of-stroke-in-the-middle-east
#6
Hamidreza Saber, Amin Amiri, Amanda G Thrift, Saverio Stranges, Reza Bavarsad Shahripour, Mohammad T Farzadfard, Naghmeh Mokhber, Réza Behrouz, Mahmoud Reza Azarpazhooh
BACKGROUND: Intracranial large-artery disease (LAD) is a predominant vascular lesion found in patients with stroke of Asian, African, and Hispanic origin, whereas extracranial LAD is more prevalent among Caucasians. These patterns are not well-established in the Middle East. We aimed to characterize the incidence, risk factors, and long-term outcome of LAD strokes in a Middle-Eastern population. METHODS: The Mashhad Stroke Incidence Study is a community-based study that prospectively ascertained all cases of stroke among the 450,229 inhabitants of Mashhad, Iran between 2006 and 2007...
August 11, 2017: Neuroepidemiology
https://www.readbyqxmd.com/read/28794250/validating-and-comparing-stroke-prognosis-scales
#7
Terence J Quinn, Sarjit Singh, Kennedy R Lees, Philip M Bath, Phyo K Myint
OBJECTIVE: To compare the prognostic accuracy of various acute stroke prognostic scales using a large, independent, clinical trials dataset. METHODS: We directly compared 8 stroke prognostic scales, chosen based on focused literature review (Acute Stroke Registry and Analysis of Lausanne [ASTRAL]; iSCORE; iSCORE-revised; preadmission comorbidities, level of consciousness, age, and neurologic deficit [PLAN]; stroke subtype, Oxfordshire Community Stroke Project, age, and prestroke modified Rankin Scale [mRS] [SOAR]; modified SOAR; Stroke Prognosis Instrument 2 [SPI2]; and Totaled Health Risks in Vascular Events [THRIVE]) using individual patient-level data from a clinical trials archive (Virtual International Stroke Trials Archive [VISTA])...
August 9, 2017: Neurology
https://www.readbyqxmd.com/read/28791985/knowledge-of-medical-students-about-epilepsy-need-for-a-change
#8
B A Ezeala-Adikaibe, T Okpara, O S Ekenze, O Onodugo, N P Ezeala-Adikaibe, T Nnaji, G Onyebueke
PURPOSE: Though most doctors in their professional life will provide care for people with epilepsy, many will not get further training in their professional life. There may be other barriers, perceived or not, to providing care to people living with epilepsy by doctors which need to be approached in the medical undergraduate curriculum and medical continuing education. The aim of this study was to determine the knowledge gaps of medical students on basic issues regarding epilepsy that could be useful in preparing training material for the students and continuous medical education for doctors working in the community...
July 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28777710/step-count-accuracy-and-reliability-of-two-activity-tracking-devices-in-people-after-stroke
#9
Samuel D Schaffer, Simon D Holzapfel, George Fulk, Pamela Rogers Bosch
BACKGROUND/PURPOSE: The increasing popularity of activity tracking devices presents an opportunity to monitor physical activity in patients after stroke. We sought to determine the reliability and accuracy of the Garmin Vivofit and Fitbit Zip for adults after stroke. METHODS: Twenty-four participants with stroke-induced hemiparesis wore a Fitbit Zip on the nonparetic hip and Garmin Vivofits on both wrists during a 6-minute walk test to determine the accuracy of the devices against video-determined step counts...
August 4, 2017: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/28776480/italian-adaptation-of-the-functional-outcome-questionnaire-aphasia-initial-psychometric-evaluation
#10
Simona Spaccavento, Elisabetta Cafforio, Fara Cellamare, Antonia Colucci, Angela Di Palma, Rosanna Falcone, Angela Craca, Anna Loverre, Roberto Nardulli, Robert L Glueckauf
PURPOSE: To evaluate the psychometric properties of the Italian version of Functional Outcome Questionnaire - Aphasia. METHODS: Two hundred and five persons with stroke-related aphasia and right hemiparesis who received ongoing assistance from a family caregiver were assessed using the Functional Outcome Questionnaire - Aphasia, Aachener Aphasie Test, Token Test, Raven's Coloured Progressive Matrices, Functional Independence Measure (FIM), Functional Assessment Measure (FAM), and Quality of Life Questionnaire for Aphasics (QLQA)...
August 4, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28776407/functional-activities-and-social-participation-after-stroke-in-rural-china-a-qualitative-study-of-barriers-and-facilitators
#11
Lifang Zhang, Tiebin Yan, Liming You, Yan Gao, Kun Li, Chunbo Zhang
OBJECTIVE: To explore the perspectives of stroke survivors in China's rural areas, particularly with respect to environmental barriers and facilitators related to their functional activity and social participation. DESIGN: Qualitative content analysis. A cross-sectional study. SETTING: In-depth interviewing in the participants' homes. SUBJECTS: In total, 18 community-dwelling stroke survivors in the rural areas of China...
August 1, 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/28768439/assessing-advanced-walking-ability-in-people-with-stroke-using-the-groningen-meander-walking-test
#12
Isaac O Tan, Joseph K-F Ng, Shamay S M Ng
OBJECTIVES: (1) To investigate the intrarater, interrater and test-retest reliabilities of the Groningen Meander Walking Test in people with stroke; (2) to compare the performance of the Groningen Meander Walking Test between people with stroke and healthy older adults; (3) to quantify any correlations between the Groningen Meander Walking Test and other stroke-specific impairment measurements; and (4) to determine the cut off time that best discriminates between 30 people with stroke and 30 age-matched healthy elderly...
August 2, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28766370/predictors-for-total-hospital-and-cardiology-cost-claims-among-patients-with-atrial-fibrillation-initiating-dabigatran-or-acenocoumarol-in-the-netherlands
#13
M S Jacobs, M W J van Leent, R G Tieleman, F G A Jansman, Q Cao, M J Postma, M van Hulst
AIMS: The prevalence of atrial fibrillation (AF) has increased over the past years due to aging of the population, and health care costs associated with AF reflect a significant financial burden. The aim of this study was to explore predictors for the real-world AF-related in-hospital costs in patients that recently initiated anticoagulation with acenocoumarol or dabigatran. METHODS: Predictors for claimed total hospital care costs and cardiology costs in AF patients were explored by using hospital financial claims data from propensity score matched patient groups in a large Dutch community hospital...
August 2, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/28765759/current-use-of-direct-oral-anticoagulants-for-atrial-fibrillation-in-japan-findings-from-the-sakura-af-registry
#14
Yasuo Okumura, Katsuaki Yokoyama, Naoya Matsumoto, Eizo Tachibana, Keiichiro Kuronuma, Koji Oiwa, Michiaki Matsumoto, Toshiaki Kojima, Shoji Hanada, Kazumiki Nomoto, Ken Arima, Fumiyuki Takahashi, Tomobumi Kotani, Yukitoshi Ikeya, Seiji Fukushima, Satoru Itoh, Kunio Kondo, Masaaki Chiku, Yasumi Ohno, Motoyuki Onikura, Atsushi Hirayama, The Sakura Af Registry Investigators
BACKGROUND: Large-scale investigations on the use of oral anticoagulants including direct oral anticoagulants (DOACs) in patients with atrial fibrillation (AF) have not included Japanese patients. METHODS: We established the multicenter SAKURA AF Registry to support prospective observational research on the status of anticoagulation treatment, especially with DOAC, for AF in Japan. We enrolled 3266 AF patients treated with warfarin (n=1577) or any of 4 DOACs (n=1689) from 63 institutions (2 cardiovascular centers, 13 affiliated hospitals or community hospitals, and 48 private clinics) in the Tokyo area...
August 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/28765127/neighbouring-green-space-and-mortality-in-community-dwelling-elderly-hong-kong-chinese-a-cohort-study
#15
Dan Wang, Kevin Ka-Lun Lau, Ruby Yu, Samuel Y S Wong, Timothy T Y Kwok, Jean Woo
OBJECTIVE: Green space has been shown to be beneficial for human wellness through multiple pathways. This study aimed to explore the contributions of neighbouring green space to cause-specific mortality. METHODS: Data from 3544 Chinese men and women (aged ≥65 years at baseline) in a community-based cohort study were analysed. Outcome measures, identified from the death registry, were death from all-cause, respiratory system disease, circulatory system disease...
August 1, 2017: BMJ Open
https://www.readbyqxmd.com/read/28761681/smoking-intensity-and-duration-is-associated-with-cardiac-structure-and-function-the-echocardiographic-study-of-hispanics-latinos
#16
J Adam Leigh, Robert C Kaplan, Katrina Swett, Pelbreton Balfour, Mayank M Kansal, Gregory A Talavera, Krista Perreira, Michael J Blaha, Emelia J Benjamin, Rosemarie Robertson, Aruni Bhartnagar, Carlos J Rodriguez
OBJECTIVE: Cardiovascular disease is the leading cause of death in smokers and this relationship is complicated by the multiplicity of cardiovascular effects of smoking. However, the relationship between intensity and duration of cigarette smoking and echocardiographic measures of right and left ventricular structure and function has been poorly studied. METHODS: We examined ECHO-SOL (Echocardiographic Study of Hispanics/Latinos) participants, a subset of the Hispanic Community Health Study/Study of Latinos...
2017: Open Heart
https://www.readbyqxmd.com/read/28760409/development-and-reliability-of-a-user-friendly-multicenter-phenotyping-application-for-hemorrhagic-and-ischemic-stroke
#17
Mayowa Owolabi, Godwin Ogbole, Rufus Akinyemi, Kehinde Salaam, Onoja Akpa, Pattanasak Mongkolwat, Adeleye Omisore, Atinuke Agunloye, Richard Efidi, Joseph Odo, Akintomiwa Makanjuola, Albert Akpalu, Fred Sarfo, Lukman Owolabi, Reginald Obiako, Kolawole Wahab, Emmanuel Sanya, Philip Adebayo, Morenikeji Komolafe, Abiodun Moshood Adeoye, Joshua Akinyemi, Godwin Osaigbovo, Taofiki Sunmonu, Paul Olowoyo, Innocent Chukwuonye, Yahaya Obiabo, Philip Ibinaiye, Abdul Dambatta, Yaw Mensah, Salaam Abdul, Eunice Olabinri, Joyce Ikubor, Olalekan Oyinloye, Femi Odunlami, Ezinne Melikam, Raelle Saulson, Philip Kolo, Adesola Ogunniyi, Bruce Ovbiagele
BACKGROUND: Annotation and Image Markup on ClearCanvas Enriched Stroke-phenotyping Software (ACCESS) is a novel stand-alone computer software application that allows the creation of simple standardized annotations for reporting brain images of all stroke types. We developed the ACCESS application and determined its inter-rater and intra-rater reliability in the Stroke Investigative Research and Educational Network (SIREN) study to assess its suitability for multicenter studies. METHODS: One hundred randomly selected stroke imaging reports from 5 SIREN sites were re-evaluated by 4 trained independent raters to determine the inter-rater reliability of the ACCESS (version 12...
July 28, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28754834/community-based-intervention-to-improve-cardiometabolic-targets-in-patients-with-stroke-a-randomized-controlled-trial
#18
Muideen T Olaiya, Dominique A Cadilhac, Joosup Kim, Mark R Nelson, Velandai K Srikanth, Richard P Gerraty, Christopher F Bladin, Sharyn M Fitzgerald, Thanh Phan, Judith Frayne, Amanda G Thrift
BACKGROUND AND PURPOSE: Many guidelines for secondary prevention of stroke focus on controlling cardiometabolic risk factors. We investigated the effectiveness of a management program for attaining cardiometabolic targets in survivors of stroke/transient ischemic attack. METHODS: Randomized controlled trial of survivors of stroke/transient ischemic attack aged ≥18 years. General practices were randomized to usual care (control) or an intervention comprising specialist review of care plans and nurse education in addition to usual care...
July 28, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28754803/uric-acid-and-incident-dementia-over-12-years-of-follow-up-a-population-based-cohort-study
#19
Augustin Latourte, Aicha Soumaré, Thomas Bardin, Fernando Perez-Ruiz, Stéphanie Debette, Pascal Richette
OBJECTIVES: In patients with gout, maintaining too low serum uric acid (SUA) level with urate-lowering therapy is a concern because uric acid is thought to be neuroprotective. However, the relation between SUA and dementia remains debated. This study aimed to investigate the impact of SUA level on the incidence of dementia. METHODS: We assessed the longitudinal association between SUA level and incident dementia (Diagnostic and Statistical Manual of Mental Disorders Version IV (DSM-IV) criteria) in a large cohort of healthy older people from the community (Three-City Dijon cohort)...
July 28, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28752781/is-age-a-key-factor-contributing-to-the-disparity-between-success-of-neuroprotective-strategies-in-young-animals-and-limited-success-in-elderly-stroke-patients-focus-on-protein-homeostasis
#20
Wei Yang, Wulf Paschen
Neuroprotection strategies to improve stroke outcome have been successful in the laboratory but not in clinical stroke trials, and thus have come under scrutiny by the medical community. Experimental stroke investigators are therefore under increased pressure to resolve this problem. Acute ischemic stroke represents a severe form of metabolic stress that activates many pathological processes and thereby impairs cellular functions. Traditionally, neuroprotection strategies were designed to improve stroke outcome by interfering with pathological processes triggered by ischemia...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
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