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https://www.readbyqxmd.com/read/28335563/the-effects-of-sweet-foods-on-the-pharmacokinetics-of-glycyrrhizic-acid-by-icelisa
#1
Bingqian Jiang, Huihua Qu, Hui Kong, Yue Zhang, Shuchen Liu, Jinjun Cheng, Xin Yan, Yan Zhao
The effect of sweet foods, such as honey, was investigated from the perspective of pharmacokinetics on the absorption of glycyrrhizic acid (GA). Due to the unique properties of indirect competitive enzyme-linked immunosorbent assay (icELISA), namely, its: specificity, sensitivity, repeatability, simple pretreatment of samples, fast and simple operation, and because it is economic and non-polluting, it has received increased attention. In this study, we used the advantages of this method to see how honey affected the pharmacokinetics of GA...
March 21, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28335506/a-colorimetric-sensor-for-the-highly-selective-detection-of-sulfide-and-1-4-dithiothreitol-based-on-the-in-situ-formation-of-silver-nanoparticles-using-dopamine
#2
Lingzhi Zhao, Liu Zhao, Yanqing Miao, Chunye Liu, Chenxiao Zhang
Hydrogen sulfide (H₂S) has attracted attention in biochemical research because it plays an important role in biosystems and has emerged as the third endogenous gaseous signaling compound along with nitric oxide (NO) and carbon monoxide (CO). Since H₂S is a kind of gaseous molecule, conventional approaches for H₂S detection are mostly based on the detection of sulfide (S(2-)) for indirectly reflecting H₂S levels. Hence, there is a need for an accurate and reliable assay capable of determining sulfide in physiological systems...
March 20, 2017: Sensors
https://www.readbyqxmd.com/read/28335462/therapeutic-potentials-of-microalgae-in-the-treatment-of-alzheimer-s-disease
#3
REVIEW
Tosin A Olasehinde, Ademola O Olaniran, Anthony I Okoh
Current research is geared towards the discovery of new compounds with strong neuroprotective potential and few or no side effects compared to synthetic drugs. This review focuses on the potentials of extracts and biologically active compounds derived from microalgal biomass for the treatment and management of Alzheimer's disease (AD). Microalgal research has gained much attention recently due to its contribution to the production of renewable fuels and the ability of alga cells to produce several secondary metabolites such as carotenoids, polyphenols, sterols, polyunsaturated fatty acids and polysaccharides...
March 18, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28335373/dietary-patterns-and-insomnia-symptoms-in-chinese-adults-the-china-kadoorie-biobank
#4
Canqing Yu, Zumin Shi, Jun Lv, Yu Guo, Zheng Bian, Huaidong Du, Yiping Chen, Ran Tao, Ying Huang, Junshi Chen, Zhengming Chen, Liming Li
Limited attention has been paid to the effect of dietary patterns on sleep problems. In the present study, we analyzed the cross-sectional data of 481,242 adults aged 30-79 years from the China Kadoorie Biobank. A laptop-based questionnaire was administered to collect information on food intakes and insomnia symptoms. Logistic regression was used to estimate the odds ratios of each insomnia symptom according to quartiles of each dietary pattern, with adjustment for potential confounders. Two major dietary patterns were derived by factor analysis...
March 4, 2017: Nutrients
https://www.readbyqxmd.com/read/28335347/the-dispersion-state-of-tangled-multi-walled-carbon-nanotubes-affects-their-cytotoxicity
#5
Chika Kuroda, Hisao Haniu, Kumiko Ajima, Manabu Tanaka, Atsushi Sobajima, Haruka Ishida, Tamotsu Tsukahara, Yoshikazu Matsuda, Kaoru Aoki, Hiroyuki Kato, Naoto Saito
The medical applications of carbon nanotubes (CNTs) have garnered much attention. However, evaluating the safety of CNTs remains difficult, and no consensus has been reached. Moreover, assessing the biosafety of multi-walled CNTs (MWCNTs), which can become tangled during manufacturing, is challenging because they do not readily disperse. We studied how the dispersion state of tangled MWCNTs affects their cytotoxicity, using three sonicators. Flotube 9110 (FT9110), tangled MWCNTs, were dispersed in two dispersants (fetal bovine serum and polysorbate 80) using a new type of sonicator (PR-1) and two conventional sonicators...
November 19, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335341/design-and-electrochemical-study-of-platinum-based-nanomaterials-for-sensitive-detection-of-nitric-oxide-in-biomedical-applications
#6
REVIEW
Maduraiveeran Govindhan, Zhonggang Liu, Aicheng Chen
The extensive physiological and regulatory roles of nitric oxide (NO) have spurred the development of NO sensors, which are of critical importance in neuroscience and various medical applications. The development of electrochemical NO sensors is of significant importance, and has garnered a tremendous amount of attention due to their high sensitivity and selectivity, rapid response, low cost, miniaturization, and the possibility of real-time monitoring. Nanostructured platinum (Pt)-based materials have attracted considerable interest regarding their use in the design of electrochemical sensors for the detection of NO, due to their unique properties and the potential for new and innovative applications...
November 14, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335340/recent-advances-in-chiral-nematic-structure-and-iridescent-color-of-cellulose-nanocrystal-films
#7
REVIEW
Derek G Gray
One unique property of cellulose nanocrystals (CNC) is their property of forming suspensions with chiral nematic order. This order can be preserved in films cast from the suspensions, raising the possibility of applications as photonic materials and templates. However, it has proved difficult to generate uniform, well-ordered chiral nematic materials from CNC. Recently, the importance of kinetic arrest due to gel formation in the later stages of evaporation has been recognized as a key step in film formation...
November 14, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335336/oral-toxicity-and-intestinal-transport-mechanism-of-colloidal-gold-nanoparticle-treated-red-ginseng
#8
Song-Hwa Bae, Jin Yu, Mi-Ran Go, Hyun-Jin Kim, Yun-Gu Hwang, Soo-Jin Choi
(1) Background: Application of nanotechnology or nanomaterials in agricultural food crops has attracted increasing attention with regard to improving crop production, quality, and nutrient utilization. Gold nanoparticles (Au-NPs) have been reported to enhance seed yield, germination rate, and anti-oxidant potential in food crops, raising concerns about their toxicity potential. In this study, we evaluated the oral toxicity of red ginseng exposed to colloidal Au-NPs during cultivation (G-red ginseng) in rats and their intestinal transport mechanism...
November 11, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335332/micromechanical-properties-of-nanostructured-clay-oxide-multilayers-synthesized-by-layer-by-layer-self-assembly
#9
Dongwei Hou, Guoping Zhang, Rohit Raj Pant, Zhongxin Wei, Shuilong Shen
Clay-based nanostructured multilayers, such as clay-polymer multilayers and clay-oxide multilayers, have attracted growing attention owing to their remarkable mechanical properties and promising application in various fields. In this paper, synthesis of a new kind of nanostructured clay-oxide multilayers by layer-by-layer self-assembly was explored. Nano-mechanical characterization of 18 clay-based multilayer samples, prepared under as-deposited (i.e., air-dried) and annealing conditions at 400 °C/600 °C with different precursor cations and multilayer structure, were carried out using nanoindentation testing, atomic force microscopy (AFM), and X-ray diffraction (XRD)...
November 8, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335322/black-phosphorus-critical-review-and-potential-for-water-splitting-photocatalyst
#10
REVIEW
Tae Hyung Lee, Soo Young Kim, Ho Won Jang
A century after its first synthesis in 1914, black phosphorus has been attracting significant attention as a promising two-dimensional material in recent years due to its unique properties. Nowadays, with the development of its exfoliation method, there are extensive applications of black phosphorus in transistors, batteries and optoelectronics. Though, because of its hardship in mass production and stability problems, the potential of the black phosphorus in various fields is left unexplored. Here, we provide a comprehensive review of crystal structure, electronic, optical properties and synthesis of black phosphorus...
October 29, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335321/two-dimensional-semiconductor-optoelectronics-based-on-van-der-waals-heterostructures
#11
REVIEW
Jae Yoon Lee, Jun-Hwan Shin, Gwan-Hyoung Lee, Chul-Ho Lee
Two-dimensional (2D) semiconductors such as transition metal dichalcogenides (TMDCs) and black phosphorous have drawn tremendous attention as an emerging optical material due to their unique and remarkable optical properties. In addition, the ability to create the atomically-controlled van der Waals (vdW) heterostructures enables realizing novel optoelectronic devices that are distinct from conventional bulk counterparts. In this short review, we first present the atomic and electronic structures of 2D semiconducting TMDCs and their exceptional optical properties, and further discuss the fabrication and distinctive features of vdW heterostructures assembled from different kinds of 2D materials with various physical properties...
October 27, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335318/a-label-free-and-sensitive-fluorescent-qualitative-assay-for-bisphenol-a-based-on-rolling-circle-amplification-exonuclease-iii-combined-cascade-amplification
#12
Xia Li, Juan Song, Qing-Wang Xue, Fu-Heng You, Xia Lu, Yan-Cong Kong, Shu-Yi Ma, Wei Jiang, Chen-Zhong Li
Bisphenol A (BPA) detection in drinking water and food packaging materials has attracted much attention since the discovery that BPA can interfere with normal physiological processes and cause adverse health effects. Here, we constructed a label-free aptamer fluorescent assay for selective and sensitive detection of BPA based on the rolling circle amplification (RCA)/Exonuclease III (Exo III)-combined cascade amplification strategy. First, the duplex DNA probe (RP) with anti-BPA aptamer and trigger sequence was designed for BPA recognition and signal amplification...
October 21, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335303/detection-of-prohibited-fish-drugs-using-silver-nanowires-as-substrate-for-surface-enhanced-raman-scattering
#13
Jia Song, Yiqun Huang, Yuxia Fan, Zhihui Zhao, Wansong Yu, Barbara A Rasco, Keqiang Lai
Surface-enhanced Raman scattering or surface-enhanced Raman spectroscopy (SERS) is a promising detection technology, and has captured increasing attention. Silver nanowires were synthesized using a rapid polyol method and optimized through adjustment of the molar ratio of poly(vinyl pyrrolidone) and silver nitrate in a glycerol system. Ultraviolet-visible spectrometry, X-ray diffraction, and transmission electron microscopy were used to characterize the silver nanowires. The optimal silver nanowires were used as a SERS substrate to detect prohibited fish drugs, including malachite green, crystal violet, furazolidone, and chloramphenicol...
September 21, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335284/graphene-enabled-electrodes-for-electrocardiogram-monitoring
#14
Numan Celik, Nadarajah Manivannan, Andrew Strudwick, Wamadeva Balachandran
The unique parameters of graphene (GN)-notably its considerable electron mobility, high surface area, and electrical conductivity-are bringing extensive attention into the wearable technologies. This work presents a novel graphene-based electrode for acquisition of electrocardiogram (ECG). The proposed electrode was fabricated by coating GN on top of a metallic layer of a Ag/AgCl electrode using a chemical vapour deposition (CVD) technique. To investigate the performance of the fabricated GN-based electrode, two types of electrodes were fabricated with different sizes to conduct the signal qualities and the skin-electrode contact impedance measurements...
August 23, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335262/nanomaterials-for-tissue-engineering-in-dentistry
#15
REVIEW
Manila Chieruzzi, Stefano Pagano, Silvia Moretti, Roberto Pinna, Egle Milia, Luigi Torre, Stefano Eramo
The tissue engineering (TE) of dental oral tissue is facing significant changes in clinical treatments in dentistry. TE is based on a stem cell, signaling molecule, and scaffold triad that must be known and calibrated with attention to specific sectors in dentistry. This review article shows a summary of micro- and nanomorphological characteristics of dental tissues, of stem cells available in the oral region, of signaling molecules usable in TE, and of scaffolds available to guide partial or total reconstruction of hard, soft, periodontal, and bone tissues...
July 21, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335258/nanostructures-derived-from-starch-and-chitosan-for-fluorescence-bio-imaging
#16
Yinxue Zu, Jingran Bi, Huiping Yan, Haitao Wang, Yukun Song, Bei-Wei Zhu, Mingqian Tan
Fluorescent nanostructures (NSs) derived from polysaccharides have drawn great attention as novel fluorescent probes for potential bio-imaging applications. Herein, we reported a facile alkali-assisted hydrothermal method to fabricate polysaccharide NSs using starch and chitosan as raw materials. Transmission electron microscopy (TEM) demonstrated that the average particle sizes are 14 nm and 75 nm for starch and chitosan NSs, respectively. Fourier transform infrared (FT-IR) spectroscopy analysis showed that there are a large number of hydroxyl or amino groups on the surface of these polysaccharide-based NSs...
July 5, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335242/targeting-and-photodynamic-killing-of-cancer-cell-by-nitrogen-doped-titanium-dioxide-coupled-with-folic-acid
#17
Jin Xie, Xiaobo Pan, Mengyan Wang, Longfang Yao, Xinyue Liang, Jiong Ma, Yiyan Fei, Pei-Nan Wang, Lan Mi
Titanium dioxide (TiO₂) has attracted wide attention as a potential photosensitizer (PS) in photodynamic therapy (PDT). However, bare TiO₂ can only be excited by ultraviolet illumination, and it lacks specific targeting ligands, which largely impede its application. In our study, we produced nitrogen-doped TiO₂ and linked it with an effective cancer cell targeting agent, folic acid (FA), to obtain N-TiO₂-FA nanoconjugates. Characterization of N-TiO₂-FA included Zeta potential, absorption spectra and thermogravimetric analysis...
June 14, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335241/erratum-mustafa-r-luo-y-wu-y-guo-r-shi-x-dendrimer-functionalized-laponite-%C3%A2-nanodisks-as-a-platform-for-anticancer-drug-delivery-nanomaterials-2015-5-1716-1731
#18
Nanomaterials Editorial Office
It has been brought to our attention that Laponite® is a trademark of BYK Additives, however the trademark symbol is missing in [1].[...].
June 14, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335197/cationic-nanoparticles-assembled-from-natural-based-steroid-lipid-for-improved-intracellular-transport-of-sirna-and-pdna
#19
Ruilong Sheng, Xiaoqing Zhuang, Zhao Wang, Amin Cao, Kaili Lin, Julian X X Zhu
Developing new functional biomaterials from biocompatible natural-based resources for gene/drug delivery has attracted increasing attention in recent years. In this work, we prepared a series of cationic nanoparticles (Diosarg-DOPE NPs) by assembly of a natural steroid diosgenin-based cationic lipid (Diosarg) with commercially-available helper lipid 1,2-dioleoyl-sn-glycero-3-phosphorethanolamine (DOPE). These cationic Diosarg-DOPE NPs were able to efficiently bind siRNA and plasmid DNA (pDNA) via electrostatic interactions to form stable, nano-sized cationic lipid nanoparticles instead of lamellar vesicles in aqueous solution...
April 13, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335040/-new-ways-of-diagnosing-adhd-in-adults
#20
Marco Grabemann, Marco Zimmermann, Laura Strunz, Monika Ebbert-Grabemann, Norbert Scherbaum, Bernhard Kis, Christian Mette
Objective Diagnosing Attention-Deficit-Hyperactivity Disorder (ADHD) in adults requires that ADHD has already been present in childhood. However, recall of ADHD-symptoms in childhood is fallible, for example influenced by mood. Furthermore, diagnostics need a procedure to handle oblivion and judgment biases. The Essen-Interview-for-school-days-related-biography (EIS-B) addresses these problems and offers a tool for retrospectively diagnosing childhood ADHD in adults. Method 36 patients with ADHD, 27 patients with depression or adjustment disorders and 39 healthy controls were included in the pilot study...
March 23, 2017: Psychiatrische Praxis
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