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https://www.readbyqxmd.com/read/28774673/can-videolaryngoscopy-be-a-first-option-in-a-patient-with-laryngeal-amyloidosis
#1
L España Fuente, G Mella Pérez, B Laserna Cocina, J L González González
Amyloidosis is a term that involves a group of diseases characterised by deposition of extracellular monoclonal light-chain fibrillar immunoglobulin aggregates in the body, including many organs, with the larynx among them. A case is presented of a 78 year-old man who was referred to our institution for strangulated umbilical hernia treatment. He suffered from progressive hoarseness and dysphagia for 5months. He had a history of primary laryngeal amyloidosis. Awake intubation was performed successful with the King Vision(®) video-laryngoscopy...
July 31, 2017: Revista Española de Anestesiología y Reanimación
https://www.readbyqxmd.com/read/28768116/on-reproductive-work-in-spain-transnational-adoption-egg-donation-surrogacy
#2
Diana Marre, Beatriz San Román, Diana Guerra
Spain's plummeting fertility since the late twentieth century may seem to reflect a waning desire for children. Nevertheless, reproductive disappointments resulting from gender inequalities cause many Spanish women to postpone motherhood and experience age-related fertility problems. For them, creating a family often becomes possible only through the reproductive labor of other women. Our analysis of transnational adoption, egg donation, and surrogacy in Spain shows how anonymity and altruism play out in these three strategies, with implications for the valuation of women's reproductive work and relationships among reproductive providers, intermediaries, recipients, and the resulting children...
August 2, 2017: Medical Anthropology
https://www.readbyqxmd.com/read/28764467/spectral-analysis-of-bistatic-scattering-from-underwater-elastic-cylinders-and-spheres
#3
Aaron M Gunderson, Aubrey L España, Philip L Marston
Far field sound scattering from underwater elastic spheres and finite cylinders is considered over the full range of scattering angles. Three models for the frequency response of the scattered field are evaluated: a hybrid finite element/propagation simulation for a finite cylinder with broadside illumination, an approximate solution for the finite cylinder, and the exact solution for a sphere. The cylinder models are shown to give comparable results, attesting to the strength of the finite cylinder approximate solution...
July 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/28757422/combined-antibacterial-tissue-regeneration-response-in-thermal-burns-promoted-by-functional-chitosan-silver-nanocomposites
#4
E Luna-Hernández, M E Cruz-Soto, F Padilla-Vaca, R A Mauricio-Sánchez, D Ramirez-Wong, R Muñoz, L Granados-López, L R Ovalle-Flores, J L Menchaca-Arredondo, A Hernández-Rangel, E Prokhorov, J L García-Rivas, B L España-Sánchez, G Luna-Bárcenas
We report the combined antibacterial/tissue regeneration responses to thermal burns promoted by functional chitosan/silver nanocomposites (CS/nAg) with ultralow silver content (0.018wt.%, 7-30nm). Our approach allows one to produce CS/nAg nanocomposites without silver nanoparticles (nAg) agglomeration, with bactericide potency higher than 1wt.% of nAg (ca. 10nm) content and, promoting the healing process in controlled thermal burns. CS/nAg films exhibit high antibacterial activity against S. aureus and P. aeruginosa after 1...
July 28, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28753391/differences-in-forearm-strength-endurance-and-hemodynamic-kinetics-between-male-boulderers-and-lead-rock-climbers
#5
S Fryer, K J Stone, J Sveen, T Dickson, V España-Romero, D Giles, J Baláš, L Stoner, N Draper
This study examined differences in the oxygenation kinetics and strength and endurance characteristics of boulderers and lead sport climbers. Using near infrared spectroscopy, 13-boulderers, 10-lead climbers, and 10-controls completed assessments of oxidative capacity index and muscle oxygen consumption (mV˙O2) in the flexor digitorum profundus (FDP), and extensor digitorum communis (EDC). Additionally, forearm strength (maximal volitional contraction MVC), endurance (force-time integral FTI at 40% MVC), and forearm volume (FAV and ΔFAV) was assessed...
July 28, 2017: European Journal of Sport Science
https://www.readbyqxmd.com/read/28728797/-prevalence-of-hypothyroidism-in-major-psychiatric-disorders-in-hospitalised-patients-in-montserrat-hospital-during-the-period-march-to-october-2010
#6
Pedro Vargas Navarro, Edgar Antonio Ibañez Pinilla, Alejandra Galeano España, Ana María Noguera Bravo, Sandra Milena Pantoja, Ana María Suárez Acosta
INTRODUCTION: Hypothyroidism results from inadequate production of thyroid hormone. It is known that there is a relationship between the major psychiatric disorders and hypothyroidism. OBJECTIVE: To determine the prevalence of hypothyroidism in patients admitted due to major psychiatric disorders in Montserrat Hospital during the period from March to October 2010. MATERIAL AND METHODS: A descriptive cross-sectional study was conducted on 105 patients admitted to Montserrat Hospital with a primary diagnosis of major psychiatric disorder (major depression, bipolar affective disorder, generalised panic disorder, panic disorder, mixed anxiety-depressive disorder, and schizophrenia) in the aforementioned period...
July 2017: Revista Colombiana de Psiquiatría
https://www.readbyqxmd.com/read/28712891/corneo-scleral-contact-lenses-in-an-uncommon-case-of-keratoconus-with-high-hyperopia-and-astigmatism
#7
Esteban Porcar, Juan Carlos Montalt, Enrique España-Gregori, Cristina Peris-Martínez
PURPOSE: To analyse the visual quality achieved by fitting corneo-scleral contact lenses (CScL) in an uncommon case of bilateral keratoconus, high hyperopia and astigmatism. METHODS: A 45-year-old man presented for eye examination due to the unsatisfactory quality of his vision wearing soft toric contact lenses. He presented high hyperopia and astigmatism with bilateral keratoconus. He was fitted with CScL to correct his irregular astigmatism and ocular aberrations...
July 13, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/28704448/rnai-based-reverse-genetics-in-the-chelicerate-model-tetranychus-urticae-a-comparative-analysis-of-five-methods-for-gene-silencing
#8
Takeshi Suzuki, Maria Andreia Nunes, María Urizarna España, Hooman Hosseinzadeh Namin, Pengyu Jin, Nicolas Bensoussan, Vladimir Zhurov, Tawhid Rahman, Rebecca De Clercq, Pierre Hilson, Vojislava Grbic, Miodrag Grbic
RNA interference (RNAi) can be used for the protection against agricultural pests through the silencing of genes required for pest fitness. To assess the potential of RNAi approaches in the two-spotted spider mite, Tetranychus urticae, we compared 5 methods for the delivery of double-stranded RNA (dsRNA). These methods include mite feeding on either (i) leaves floating on a dsRNA solution, (ii) dsRNA-expressing plants, (iii) artificial diet supplemented with dsRNA, or (iv) dsRNA-coated leaves, and (v) mite soaking in a dsRNA solution...
2017: PloS One
https://www.readbyqxmd.com/read/28699287/an-alternative-method-for-the-analysis-of-melanin-production-in-cryptococcus-neoformans-sensu-lato-and-cryptococcus-gattii-sensu-lato
#9
Raimunda S N Brilhante, Jaime D A España, Lucas P de Alencar, Vandbergue S Pereira, Débora de S C M Castelo-Branco, Waldemiro de A Pereira-Neto, Rossana de A Cordeiro, José J C Sidrim, Marcos F G Rocha
Melanin is an important virulence factor for several microorganisms, including Cryptococcus neoformans sensu lato and Cryptococcus gattii sensu lato, thus, the assessment of melanin production and its quantification may contribute to the understanding of microbial pathogenesis. The objective of this study was to standardise an alternative method for the production and indirect quantification of melanin in C. neoformans sensu lato and C. gattii sensu lato. Eight C. neoformans sensu lato and three C. gattii sensu lato, identified through URA5 methodology, Candida parapsilosis ATCC 22019 (negative control) and one Hortaea werneckii (positive control) were inoculated on minimal medium agar with or without L-DOPA, in duplicate, and incubated at 35°C, for 7 days...
July 12, 2017: Mycoses
https://www.readbyqxmd.com/read/28690838/recent-advances-in-high-throughput-approaches-to-dissect-enhancer-function
#10
REVIEW
David Santiago-Algarra, Lan T M Dao, Lydie Pradel, Alexandre España, Salvatore Spicuglia
The regulation of gene transcription in higher eukaryotes is accomplished through the involvement of transcription start site (TSS)-proximal (promoters) and -distal (enhancers) regulatory elements. It is now well acknowledged that enhancer elements play an essential role during development and cell differentiation, while genetic alterations in these elements are a major cause of human disease. Many strategies have been developed to identify and characterize enhancers. Here, we discuss recent advances in high-throughput approaches to assess enhancer activity, from the well-established massively parallel reporter assays to the recent clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9-based technologies...
2017: F1000Research
https://www.readbyqxmd.com/read/28690512/bioinspired-architecture-selection-for-multitask-learning
#11
Andrés Bueno-Crespo, Rosa-María Menchón-Lara, Raquel Martínez-España, José-Luis Sancho-Gómez
Faced with a new concept to learn, our brain does not work in isolation. It uses all previously learned knowledge. In addition, the brain is able to isolate the knowledge that does not benefit us, and to use what is actually useful. In machine learning, we do not usually benefit from the knowledge of other learned tasks. However, there is a methodology called Multitask Learning (MTL), which is based on the idea that learning a task along with other related tasks produces a transfer of information between them, what can be advantageous for learning the first one...
2017: Frontiers in Neuroinformatics
https://www.readbyqxmd.com/read/28687483/percutaneous-tibial-nerve-stimulation-therapy-for-overactive-bladder-syndrome-clinical-effectiveness-urodynamic-and-durability-evaluation
#12
Sergío Del Río-Gonzalez, Isabel M Aragon, Elisabeth Castillo, Francisco Milla-España, Alejandro Galacho, Javier Machuca, María F Lara, Bernardo Herrera-Imbroda
OBJECTIVE: To evaluate percutaneous tibial nerve stimulation (PTNS) effectiveness, durability, and impact on the pathophysiology of overactive bladder syndrome (OAB) in patients who have been previously treated with antimuscarinics without success. MATERIALS AND METHODS: A prospective study that included 200 women diagnosed with OAB between 2007 and 2015 at Virgen de la Victoria University Hospital (Málaga, Spain) was conducted. OAB patients were treated with PTNS therapy after antimuscarinic treatment failed...
July 4, 2017: Urology
https://www.readbyqxmd.com/read/28686745/protocols-for-the-delivery-of-small-molecules-to-the-two-spotted-spider-mite-tetranychus-urticae
#13
Takeshi Suzuki, María Urizarna España, Maria Andreia Nunes, Vladimir Zhurov, Wannes Dermauw, Masahiro Osakabe, Thomas Van Leeuwen, Miodrag Grbic, Vojislava Grbic
The two-spotted spider mite, Tetranychus urticae, is a chelicerate herbivore with an extremely wide host range and an extraordinary ability to develop pesticide resistance. Due to its responsiveness to natural and synthetic xenobiotics, the spider mite is becoming a prime pest herbivore model for studies of the evolution of host range, plant-herbivore interactions and mechanisms of xenobiotic resistance. The spider mite genome has been sequenced and its transcriptional responses to developmental and various biotic and abiotic cues have been documented...
2017: PloS One
https://www.readbyqxmd.com/read/28668632/urban-sewage-lipids-in-the-suspended-particulate-matter-of-a-coral-reef-under-river-influence-in-the-south-west-gulf-of-mexico
#14
Laura Carreón-Palau, Christopher C Parrish, Horacio Pérez-España
Nutritional quality of suspended particulate matter (SPM) and the degree of human fecal pollution in the largest coral reef system in the southwest Gulf of Mexico were evaluated using lipid classes, fatty acids (FA) and sterols in the dry and rainy seasons. High proportions of triacylglycerols and saturated and monounsaturated FA were detected in the SPM however it was considered poor quality because it had low proportions of highly unsaturated FA which can be used to determine production of marine biogenic material of dietary value to pelagic and benthic organisms...
June 22, 2017: Water Research
https://www.readbyqxmd.com/read/28667509/hypocretin-receptor-1-blockade-produces-bimodal-modulation-of-cocaine-associated-mesolimbic-dopamine-signaling
#15
K A Levy, Z D Brodnik, J K Shaw, D A Perrey, Y Zhang, R A España
RATIONALE: Cocaine addiction is a chronic psychiatric disorder characterized by pathological motivation to obtain cocaine and behavioral and neurochemical hypersensitivity to cocaine-associated cues. These features of cocaine addiction are thought to be driven by aberrant phasic dopamine signaling. We previously demonstrated that blockade of the hypocretin receptor 1 (HCRTr1) attenuates cocaine self-administration and reduces cocaine-induced enhancement of dopamine signaling. Despite this evidence, the effects of HCRTr1 blockade on endogenous phasic dopamine release are unknown...
June 30, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/28665173/serial-assessment-of-gray-matter-abnormalities-following-sport-related-concussion
#16
Lezlie Espana, Ryan Lee, Josef Ling, Andreas Jeromin, Andrew Mayer, Timothy Meier
There is an urgent need to characterize the acute physiological effects of sport-related concussion (SRC). We investigated the effects of SRC on gray matter structure and diffusion metrics in collegiate athletes at 1.64 days (T1; n=33), 8.33 days (T2; n=30), and 32.15 days (T3; n=36) post-concussion, with healthy collegiate contact-sport athletes serving as controls (HA; n=46). Plasma levels of GFAP were assessed in a subset of athletes. We hypothesized that acute SRC would be associated with increased fractional anisotropy (FA), decreased mean diffusivity (MD), and increased GFAP relative to non-injured HA, without acute differences in gray matter volume or cortical thickness...
June 30, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28650514/automatic-segmentation-of-the-spine-by-means-of-a-probabilistic-atlas-with-a-special-focus-on-ribs-suppression
#17
Silvia Ruiz-España, Juan Domingo, Antonio Díaz-Parra, Esther Dura, Víctor D'Ocón-Alcañiz, Estanislao Arana, David Moratal
PURPOSE: The development of automatic and reliable algorithms for the detection and segmentation of the vertebrae are of great importance prior to any diagnostic task. However, an important problem found to accurately segment the vertebrae is the presence of the ribs in the thoracic region. To overcome this problem, a probabilistic atlas of the spine has been developed dealing with the proximity of other structures, with a special focus on ribs suppression. METHODS: The data sets used consist of Computed Tomography images corresponding to 21 patients suffering from spinal metastases...
June 26, 2017: Medical Physics
https://www.readbyqxmd.com/read/28641952/the-effect-of-tissue-segmented-attenuation-maps-on-pet-quantification-with-a-special-focus-on-large-arteries
#18
A Mota-Cobian, J C Alonso-Farto, L Fernández-Friera, J Sánchez-González, B López-Melgar, L J Jiménez-Borreguero, V Fuster, J Ruiz-Cabello, S España
OBJECTIVES: Accuracy on quantitative PET image analysis relies on the correct application of attenuation correction which is one of the major challenges for PET/MRI that remains to be solved. The purpose of this study is to evaluate the effect of MRI-based attenuation maps and the use of flexible coils on the quantitative accuracy of PET images with a special focus on large arteries. MATERIALS AND METHODS: PET/CT data from eight oncologic patients was used. PET data was reconstructed using attenuation maps with different level of detail emulating several approaches available on current PET/MRI scanners...
June 19, 2017: Revista Española de Medicina Nuclear e Imagen Molecular
https://www.readbyqxmd.com/read/28633626/age-related-differences-in-management-and-outcomes-in-hospitalized-healthy-and-well-functioning-bacteremic-pneumococcal-pneumonia-patients-a-cohort-study
#19
Luis A Ruiz, Pedro P España, Ainhoa Gómez, Amaia Bilbao, Carmen Jaca, Amaia Arámburu, Alberto Capelastegui, Marcos I Restrepo, Rafael Zalacain
BACKGROUND: Limited data are available regarding fit and healthy patients with pneumonia at different ages. We evaluated the association of age with clinical presentation, serotype and outcomes among healthy and well-functioning patients hospitalized for bacteremic pneumococcal community-acquired pneumonia. METHODS: We performed a prospective cohort study of consecutive healthy and well-functioning patients hospitalized for this type of pneumonia. Patients were stratified into younger (18 to 64 years) and older (≥65 years) groups...
June 20, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28630103/up-regulation-of-ep2-and-ep3-receptors-in-human-tolerogenic-dendritic-cells-boost-the-immunosuppressive-activity-of-pge2
#20
Georgina Flórez-Grau, Raquel Cabezón, Kyra J E Borgman, Carolina España, Juan Jose Lozano, Maria F Garcia-Parajo, Daniel Benítez-Ribas
Dendritic cells (DCs) are APCs essential in regulating the immune response. PGE2, produced during inflammation, has a pivotal role in the maturation of DCs and, therefore, is vital for the immune response. The large variety of biologic functions governed by PGE2 is mediated by its signaling through 4 distinct E-type prostanoid (EP) receptors. Immunogenic DCs express EP2 and EP4, which mediate the PGE2 signaling. However, the expression and function of EP receptors in human tolerogenic DCs (tol-DCs), which present an inhibitory phenotype, have not yet, to our knowledge, been assessed...
June 19, 2017: Journal of Leukocyte Biology
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