keyword
https://read.qxmd.com/read/38455168/food-consumption-by-nova-food-classification-metabolic-outcomes-and-barriers-to-healthy-food-consumption-among-university-students
#21
JOURNAL ARTICLE
Elizabeth Sekyi, Nana Ama Frimpomaa Agyapong, Guy Eshun
The NOVA food classification system is a simple tool that can be used to assess the consumption levels of different categories of foods based on their level of processing. The degree to which food is processed has a significant impact on health outcomes. In Ghana, no study exists on the consumption of the different NOVA food groups among tertiary students and how it relates to their metabolic outcomes. This study assessed the frequency of food intake according to the NOVA classification and how they relate to body mass index, waist circumference, and blood pressure...
March 2024: Food Science & Nutrition
https://read.qxmd.com/read/38454879/complementary-feeding-practices-for-children-aged-6-23-months-in-early-childhood-education-institutions-in-urban-china-a-cross-sectional-study
#22
JOURNAL ARTICLE
Qiong Wu, Na Meng, Xiaotong Wang, Lin Li, Jian Zhang, Yiwen Huang, Yanfeng Zhang
BACKGROUND: Appropriate infant and young child feeding (IYCF) plays a crucial role in promoting the healthy growth of children. Currently, many Chinese urban parents are seeking care of children from the early childhood education (ECE) institutions, however, little is known about the feeding practices of infants and young children in ECE institutions. This study aims to investigate the complementary feeding practices for Chinese urban children aged 6-23 months in ECE institutions and explore potential factors influencing their feeding practices...
March 8, 2024: Journal of Global Health
https://read.qxmd.com/read/38453435/efficacy-tolerability-and-safety-of-the-oral-phosphate-binder-vs-505-ap301
#23
JOURNAL ARTICLE
Bing Zhuang, Liangying Gan, Bin Liu, Weijie Yuan, Ming Shi, Ai Peng, Lihua Wang, Xiaolan Chen, Tongqiang Liu, Shiying Zhang, Song Wang, Qing Gao, Baoxing Wang, Huixiao Zheng, Changhua Liu, Yuan Luo, Hong Ye, Hongli Lin, Yiwen Li, Qiang He, Feng Zheng, Ping Luo, Gang Long, Wei Lu, Kanghui Li, Junwei Yang, Yingxue Cathy Liu, Zhizheng Zhang, Xiaolin Li, Weifeng Zhang, Li Zuo
BACKGROUND: VS-505 (AP301), an acacia and ferric oxyhydroxide polymer, is a novel fiber-iron-based phosphate binder. This two-part phase 2 study evaluated the tolerability, safety, and efficacy of oral VS-505 administered three times daily with meals in treating hyperphosphatemia in chronic kidney disease (CKD) patients receiving maintenance hemodialysis (MHD). METHODS: In Part 1, patients received dose-escalated treatment with VS-505 2.25, 4.50, and 9.00 g/day for 2 weeks each, guided by serum phosphorus levels...
March 7, 2024: Nephrology, Dialysis, Transplantation
https://read.qxmd.com/read/38453255/prior-acute-exercise-restores-postprandial-fat-oxidation-in-active-cannabis-users
#24
JOURNAL ARTICLE
Matthew M Schubert, Samantha Terauds, Maren Plant, Grace Handler, Colin Atkins, Casandra Mendez
Data suggest cannabis users have similar or lower levels of blood lipids compared to nonusers. However, the extent to which cannabis users experience postprandial lipemia is not known. Eleven cannabis users and 11 nonusers completed either rest or 1 h of exercise at their ventilatory threshold the evening before a meal tolerance test (MTT). Substrate oxidation, blood pressure, and capillary blood were obtained before and every 30-60 min post-meal for 3 h. Linear mixed models were utilized to examine differences in variables between groups, conditions, across time, and their interactions...
March 2024: Physiological Reports
https://read.qxmd.com/read/38450556/a-randomized-clinical-trial-for-meal-bolus-decision-using-learning-based-control-in-adults-with-type-2-diabetes
#25
JOURNAL ARTICLE
Wei Liu, Deheng Cai, Rui Zhang, Xiuying Zhang, Xiaoling Cai, Liyuan Tao, Xueyao Han, Yingying Luo, Meng Li, Wenjing Wu, Yumin Ma, Dawei Shi, Linong Ji
BACKGROUND: We proposed an artificial-pancreas-like algorithm (AP-A) which could automatically determine the pre-prandial insulin dose based on intermittently scanned continuous glucose monitoring (isCGM) data trajectories in multiple dose injection (MDI) therapy. We aim to determine whether pre-prandial insulin dose adjustments guided by the AP-A is as effective and safe as physician decisions. METHODS: We performed a randomized, single-blind, clinical trial at a tertiary, referral hospital in Beijing, China...
March 7, 2024: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/38449721/development-of-an-inpatient-protocol-for-adolescents-with-avoidant-restrictive-food-intake-disorder-a-case-study
#26
JOURNAL ARTICLE
Danielle Pogos, Melissa Whitelaw, Claire Burton, Susan M Sawyer
INTRODUCTION: Avoidant/restrictive food intake disorder (ARFID) is an eating disorder characterised by a pattern of eating that leads to failure to meet appropriate nutritional and/or energy needs. METHOD: In the absence of evidence-based inpatient guidelines for adolescents with ARFID, we set out to develop and pilot an inpatient protocol for adolescents with ARFID. Identification of the key differences between managing inpatients with ARFID and anorexia nervosa (AN) led to modification of an existing AN protocol with the goals of better meeting patient needs, enhancing alignment with outpatient care, and improving outcomes...
March 2024: Journal of the Canadian Academy of Child and Adolescent Psychiatry
https://read.qxmd.com/read/38448968/molecular-and-entomological-surveillance-of-malaria-vectors-in-urban-and-rural-communities-of-benguela-province-angola
#27
JOURNAL ARTICLE
Gonçalo Alves, Arlete Dina Troco, Gonçalo Seixas, Rebecca Pabst, Alfredo Francisco, Cani Pedro, Luzala Garcia, José Franco Martins, Sergio Lopes
BACKGROUND: Malaria is a major public health problem in Angola, with Anopheles gambiae sensu lato (s.l.) and An. funestus s.l. being the primary vectors. This study aimed to clarify the information gaps concerning local Anopheles mosquito populations. Our objectives were to assess their abundance, geographical dispersion, and blood-feeding patterns. We also investigated their insecticide resistance. Molecular methods were used to identify sibling species, determine the origin of blood meals, measure Plasmodium falciparum infection rates, and detect the presence of knockdown resistance (kdr) mutations...
March 6, 2024: Parasites & Vectors
https://read.qxmd.com/read/38446388/safety-tolerability-and-pharmacokinetics-of-the-monoamine-oxidase-b-inhibitor-hec122505-and-its-major-metabolite-after-single-and%C3%A2-multiple-ascending-dose-and-food-effect-study-in-healthy-chinese-subjects
#28
JOURNAL ARTICLE
Chuanfei Jin, Chao Yi, Kangzhi Chen, Haiping Liang
BACKGROUND AND OBJECTIVES: HEC122505 is a potent and selectively monoamine oxidase B inhibitor that is safe and well-tolerated in preclinical models of Parkinson's disease. The objectives of single ascending dose and multiple dose pharmacokinetic trials of HEC122505 oral tablets were to determine the safety and tolerability of HEC122505, and to examine the food effect on the pharmacokinetic parameters of HEC122505 and its major metabolite HEC129870. METHODS: The phase I study (NCT04625361) consisted of three arms: single ascending dose study (5, 20, 50, 100, 200, 300 or 400 mg HEC122505 tablets or placebo), multiple ascending dose study (20, 50 or 100 mg HEC122505 tablets or placebo once daily), and food effect (100 mg HEC122505 tablets single dose after a high-fat, high-calorie meal)...
March 6, 2024: European Journal of Drug Metabolism and Pharmacokinetics
https://read.qxmd.com/read/38445084/a-streamlined-multidisciplinary-metabolic-clinic-in-psychiatric-recovery-service-a-pilot-study
#29
JOURNAL ARTICLE
Kelvin Cy Leung, Bianca Bakr, Cindy Chung, Mayuri Parmar, James Elhindi, Vlasios Brakoulias
BACKGROUND: The metabolic syndrome (MetS) is a collection of risk factors for cardiovascular disease and type-2 diabetes, that includes central obesity, hypertension, hyperglycaemia and dyslipidaemia. An audit indicated inadequate MetS screening in an Australian psychiatric recovery service. OBJECTIVES: We aimed to improve MetS screening, identification and intervention by offering streamlined lifestyle education, clinical reviews and discharge planning. This pilot program prioritized holistic, culturally-sensitive, patient-centric, and trauma-informed approaches to enhance metabolic health outcomes...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38443111/an-evaluation-of-gastric-emptying-scintigraphy-protocols-in-health-care-institutions-when-compared-with-the-society-of-nuclear-medicine-and-molecular-imaging-procedure-guidelines
#30
JOURNAL ARTICLE
Valentina M Muskus Veitia, Mindy C Hawkins Barnett, Sarah R Gibbons, Deborah L LeMay, S Gregory Jennings
This study aimed to analyze the compliance of health care institutions with the Society of Nuclear Medicine and Molecular Imaging (SNMMI) procedure guidelines for gastric emptying scintigraphy (GES). Methods: A 19-question survey on demographics and the GES protocol was conducted using a Google form. The demographic questions covered position, number of technologists in the department, location, type of health care institution, and number of GES studies per month. The protocol questions included patient preparation, meal preparation, withholding of scheduled medications, radiopharmaceutical type, and radiopharmaceutical dose...
March 5, 2024: Journal of Nuclear Medicine Technology
https://read.qxmd.com/read/38443107/gastric-emptying-studies-in-pediatrics-a-cincinnati-children-s-hospital-experience
#31
JOURNAL ARTICLE
Joseph Joby MacLean, Khalil El-Chammas
Gastric emptying studies are routinely performed in many nuclear medicine departments; however, there are many different techniques used to perform the procedure across the country. Creating consistency in clinical practice will aid gastroenterologists in diagnosing and treating illnesses associated with abnormalities related to gastric emptying. In 2017, Cincinnati Children's Hospital adopted adult standards for pediatric gastric emptying studies that included a standard meal along with imaging over the course of 4 h...
March 5, 2024: Journal of Nuclear Medicine Technology
https://read.qxmd.com/read/38442226/the-effects-of-hydrolyzed-protein-on-macronutrient-digestibility-fecal-metabolites-and-microbiota-oxidative-stress-and-inflammatory-biomarkers-and-skin-and-coat-quality-in-adult-dogs
#32
JOURNAL ARTICLE
Clare Hsu, Fabio Marx, Ryan Guldenpfennig, Negin Valizadegan, Maria R C de Godoy
Research on protein hydrolysates has observed various properties and functionalities on ingredients depending on the type of hydrolysate. The objective of this study was to evaluate the effects of hydrolyzed chicken protein that was incorporated into diets on digestibility, gut health, skin and coat health, oxidative stress, and intestinal inflammation markers in healthy adult dogs. Five complete and balanced diets were manufactured: 1) CONd: 25% chicken meal diet; 2) 5% CLHd: 5% chicken liver and heart hydrolysate plus 20% chicken meal diet; 3) CLHd: 25% chicken liver and heart hydrolysate diet; 4) 5% CHd: 5% chicken hydrolysate plus 20% chicken meal diet; 5) CHd: 25% chicken hydrolysate diet...
March 5, 2024: Journal of Animal Science
https://read.qxmd.com/read/38440796/use-of-magnetic-resonance-imaging-for-visualization-of-oral-dosage-forms-in-the-human-stomach-a-scoping-review
#33
REVIEW
Tejal Akbar, Pavel Gershkovich, Konstantinos Stamatopoulos, Penny A Gowland, Snow Stolnik, James Butler, Luca Marciani
Oral dosage forms are the most widely and frequently used formulations to deliver active pharmaceutical ingredients (APIs), due to their ease of administration and noninvasiveness. Knowledge of intragastric release rates and gastric mixing is crucial for predicting the API release profile, especially for immediate release formulations. However, knowledge of the intragastric fate of oral dosage forms in vivo to date is limited, particularly for dosage forms administered when the stomach is in the fed state. An improved understanding of gastric food processing, dosage form location, disintegration times, and food effects is essential for greater understanding for effective API formulation design...
March 5, 2024: Molecular Pharmaceutics
https://read.qxmd.com/read/38440689/two-stage-fermentation-of-corn-and-soybean-meal-mixture-by-bacillus-subtilis-and-lactobacillus-acidophilus-to-improve-feeding-value-optimization-physicochemical-property-and-microbial-community
#34
JOURNAL ARTICLE
Tonghao Du, Shijin Xiong, Li Wang, Guangxian Liu, Qianqian Guan, Mingyong Xie, Tao Xiong, Jinqing Huang
UNLABELLED: Microbial treatment can reduce the antinutritional factors and allergenic proteins in corn-soybean meal mixture (CSMM), but the role of the microbial community in hypoallergenicity and digestibility during the fermentation process remains unclear. Therefore, the fermentation strains of Bacillus and LAB were determined, and the compatibility and fermentation process of two-stage solid fermentation composite bacteria were optimized, and the dynamic changes in physicochemical property and microbial community during two-stage fermentation were investigated...
April 2024: Food Science and Biotechnology
https://read.qxmd.com/read/38438938/food-and-nutrition-knowledge-attitudes-and-practices-among-children-in-public-primary-school-with-canteens-in-southern-benin-a-case-study
#35
JOURNAL ARTICLE
Faïck Bello, Elie Koukou, Sam Bodjrenou, Céline Termote, Paulin Azokpota, Waliou Amoussa Hounkpatin
BACKGROUND: Food and nutrition notion among schoolchildren in Benin is still less documented. Few studies have examined the determinants of food and nutrition among schoolchildren while others have attempted to link knowledge, attitudes and practices to diet. The present study aims to evaluate food and nutrition knowledge, attitudes and practices among schoolchildren enrolled in public primary schools canteens in Cotonou and its surroundings. METHODS: A diagnostic study was conducted in twelve public primary schools with canteens...
March 4, 2024: BMC Nutrition
https://read.qxmd.com/read/38438850/analyzing-postprandial-metabolomics-data-using-multiway-models-a-simulation-study
#36
JOURNAL ARTICLE
Lu Li, Shi Yan, Barbara M Bakker, Huub Hoefsloot, Bo Chawes, David Horner, Morten A Rasmussen, Age K Smilde, Evrim Acar
BACKGROUND: Analysis of time-resolved postprandial metabolomics data can improve the understanding of metabolic mechanisms, potentially revealing biomarkers for early diagnosis of metabolic diseases and advancing precision nutrition and medicine. Postprandial metabolomics measurements at several time points from multiple subjects can be arranged as a subjects by metabolites by time points array. Traditional analysis methods are limited in terms of revealing subject groups, related metabolites, and temporal patterns simultaneously from such three-way data...
March 4, 2024: BMC Bioinformatics
https://read.qxmd.com/read/38437987/carbohydrate-counting-knowledge-and-ambulatory-glucose-profile-in-persons-living-with-type-1-diabetes
#37
JOURNAL ARTICLE
Sopio Tatulashvili, Bleuenn Dreves, Laurent Meyer, Emmanuel Cosson, Michael Joubert
UNLABELLED: Context The amount of consumed carbohydrates is the strongest factor influencing glucose levels during the four hours following a meal. Our aim was to evaluate the association between carbohydrate counting knowledge and continuous glucose monitoring (CGM) parameters in patients with type 1 diabetes (T1D) using different insulin regimens. METHOD: In this multicenter prospective study, the GluciQuizz questionnaire was used to evaluate carbohydrate knowledge...
March 2, 2024: Diabetes Research and Clinical Practice
https://read.qxmd.com/read/38437354/libs-combined-with-sg-spxy-spectral-data-pre-processing-for-cement-raw-meal-composition-analysis
#38
JOURNAL ARTICLE
Yongqi Cai, Xiaoyu Ma, Bing Huang, Rongfeng Zhang, Xiaohong Wang
Rapid testing of cement raw meal plays a crucial role in the cement production process, so there is an urgent need for a fast and accurate testing method. In this paper, a method based on the Savitzky-Golay (SG) smoothing and sample set partitioning based on joint x - y distance (SPXY) spectral data pre-processing is proposed to improve the accuracy of the laser-induced breakdown spectroscopy (LIBS) technique for quantitative analysis of cement raw meal components. Firstly, the spectral data is denoised by SG smoothing, which effectively reduces the noise and baseline variations in the spectra...
February 20, 2024: Applied Optics
https://read.qxmd.com/read/38436633/feasibility-study-of-a-low-carbohydrate-time-restricted-eating-protocol-for-insulin-using-type-2-diabetic-patients
#39
JOURNAL ARTICLE
Philip N Zimmermann, Linda M Baier Manwell, Fauzia Osman, David Feldstein
INTRODUCTION: Low-carbohydrate diets and time-restricted eating are methods to improve hemoglobin A1C in patients with type 2 diabetes. However, insulin-using patients are often counseled against these practices due to hypoglycemia concerns. This observational study evaluated a protocol utilizing both methods coupled with proactive insulin titration. OBJECTIVES: To evaluate the safety and feasibility of a timed eating protocol for insulin-using patients and to assess its impact on outcomes, including insulin use and hemoglobin A1C...
February 2024: WMJ: Official Publication of the State Medical Society of Wisconsin
https://read.qxmd.com/read/38436494/effects-of-meal-type-on-the-bioavailability-of-vutiglabridin-a-novel-anti-obesity-agent-in-healthy-subjects
#40
RANDOMIZED CONTROLLED TRIAL
Heejae Won, Deok Yong Yoon, Sangmi Lee, Joo-Youn Cho, Jaeseong Oh, In-Jin Jang, Sang-Ku Yoo, Kyung-Sang Yu
Vutiglabridin, which affects the pharmacokinetics (PKs) of food, is currently under clinical development for the treatment of obesity. This study aimed to evaluate the effects of low- and high-fat meals on PKs of vutiglabridin in healthy male subjects. A randomized, open-label, single-dose, three-period, six-sequence crossover study was conducted. The subjects received a single oral dose of vutiglabridin 480 mg in a fasted state, 30 min after the intake of a low-fat meal (total 500-600 kcal, fat content 100-125 kcal) and high-fat meal (total 800-1000 kcal, fat content 500-600 kcal), with a 21-day washout period...
March 2024: Clinical and Translational Science
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