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https://www.readbyqxmd.com/read/28724184/treatment-of-gestational-diabetes-mellitus-with-myo-inositol-analyzing-the-cutting-edge-starting-from-a-peculiar-case
#1
L Costabile, V Unfer
OBJECTIVE: The robust data about myo-inositol (Myo-Ins) safety profile and effectiveness opened a new scenario for the treatment and prevention of Gestational Diabetes Mellitus (GDM). We report our experience about a case of GDM successfully treated with Myo-Ins. PATIENTS AND METHODS: An overweight 29-year-old Caucasian pregnant woman, nulliparous, affected by GDM, according to the National Institute for Health and Care Excellence (NICE) Guideline. After diagnosis, the patient underwent regular glycemia checks: mean fasting blood glucose value was 103...
June 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28723886/prolonged-viral-replication-and-longitudinal-viral-dynamic-differences-among-respiratory-syncytial-virus-rsv-infected-infants
#2
Monica E Brint, Joshua M Hughes, Aditya Shah, Chelsea R Miller, Lisa G Harrison, Elizabeth A Meals, Jacqueline Blanch, Charlotte R Thompson, Stephania A Cormier, John P DeVincenzo
BACKGROUND: Longitudinal RSV dynamics have not been well-studied despite existence of factors favoring prolonged RSV replication including: high mutation rates allowing rapid evolution and potential escape from immune control. We therefore measured viral load in previously RSV-naïve infants over prolonged time-spans. METHODS: During 2014-2015, quantitative nasal aspirates were collected from 51 RSV-PCR+ infants. Multiple parallel assessments of viral loads were quantified at each collected time point using a well-validated real-time qRT-PCR assay...
July 19, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28721668/quantitative-analysis-of-s-mutans-lactobacillus-and-bifidobacterium-found-in-initial-and-mature-plaques-in-thai-children-with-early-childhood-caries
#3
K Mitrakul, S Chanvitan, A Jeamset, K Vongsawan
AIMS: To quantify Streptococcus mutans, lactobacillus and bifidobacterium in initial and mature plaque collected from children with severe early childhood caries (S-ECC) and caries-free (CF) groups and to analyse the association between these bacteria and caries-related factors in each group. STUDY DESIGN: A collection of 120 initial and overnight supra-gingival plaques were collected from Thai children aged 2-5 years-old (S-ECC = 60, CF = 60). Plaque, gingival indices and decayed, missing, filled tooth (dmft) scores were recorded...
July 18, 2017: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/28721279/age-related-circadian-disorganization-caused-by-sympathetic-dysfunction-in-peripheral-clock-regulation
#4
Yu Tahara, Yuta Takatsu, Takuya Shiraishi, Yosuke Kikuchi, Mayu Yamazaki, Hiroaki Motohashi, Aya Muto, Hiroyuki Sasaki, Atsushi Haraguchi, Daisuke Kuriki, Takahiro J Nakamura, Shigenobu Shibata
The ability of the circadian clock to adapt to environmental changes is critical for maintaining homeostasis, preventing disease, and limiting the detrimental effects of aging. To date, little is known about age-related changes in the entrainment of peripheral clocks to external cues. We therefore evaluated the ability of the peripheral clocks of the kidney, liver, and submandibular gland to be entrained by external stimuli including light, food, stress, and exercise in young versus aged mice using in vivo bioluminescence monitoring...
2017: NPJ Aging and Mechanisms of Disease
https://www.readbyqxmd.com/read/28717811/effect-on-body-weight-quality-of-life-and-appetite-following-individualized-nutritional-counselling-to-home-living-elderly-after-rehabilitation-an-open-randomized-trial
#5
J Andersson, E Hulander, E Rothenberg, P Ole Iversen
OBJECTIVES: We examined if individually-adapted nutritional counselling could prevent > 5% weight loss among elderly patients 3 months after discharge from a rehabilitation institution. In addition we assessed quality of life (QoL) and appetite. DESIGN: An open, randomized trial. SETTING: Godthaab Health and Rehabilitation Institution in Bærum, Norway. PARTICIPANTS: Patients identified as being undernourished or at risk of disease-related malnutrition using the Nutritional Risk Screening tool NRS-2002...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/28713117/alteration-in-taste-perception-among-young-children-during-the-use-of-removable-orthodontic-appliance-therapy
#6
Priyanka Razdan, V S Sakthivel, Zuber A Naqvi, Vinod Goyal, Swati Tripathi, Smita Singh
BACKGROUND: The sense of smell is very influential in the taste of foods. If the smell pleases us, we anticipate the taste of the food with a great deal of relish. If our sense of smell is impaired, so is our taste. The effect of appliance on taste perceptions has always had a controversial subject. MATERIALS AND METHODS: The present study was designed to analyze the change in taste perception in children using removable orthodontic appliances. All the selected volunteers were given different taste stimuli and were asked to score as per their perception...
July 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28711619/adsorption-of-pb-ii-ions-from-aqueous-environment-using-eco-friendly-chitosan-schiff-s-base-fe3o4-csb-fe3o4-as-an-adsorbent-kinetics-isotherm-and-thermodynamic-studies
#7
Zhang Weijiang, Zhang Yace, Gutha Yuvaraja, Xu Jiao
Chitosan and its derivatives can be used to modify magnetic materials to promote the adsorption properties of the magnetic materials for the removal of meal ions. In this study a novel CSB@Fe3O4 was prepared, characterized by FTIR, SEM, TEM, and VSM analysis and utilized as an adsorbent material for the removal of Pb(II) ions from aqueous solution. Batch studies were performed to evaluate the influences of various experimental parameters like pH, adsorbent dosage, contact time, initial concentration, and the effect of temperature...
July 12, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28707862/gastric-emptying-and-related-symptoms-in-patients-treated-with-buspirone-amitriptyline-or-clebopride-a-real-world-study-by-13c-octanoic-acid-breath-test
#8
Gian P Caviglia, Carlo Sguazzini, Fabio Cisaro', Davide G Ribaldone, Chiara Rosso, Sharmila Fagoonee, Antonina Smedile, Giorgio M Saracco, Marco Astegiano, Rinaldo Pellicano
BACKGROUND: Gastric motility is a key-factor in the pathogenesis of functional dyspepsia (FD). 13C-octanoic acid breath test (OBT) is a tool used for measuring gastric emptying time in clinicalsetting. We aimed to investigate the variation in FD symptoms and OBT parameters after treatment with buspirone, amitriptyline or clebopride. METHODS: Between Jan-2007 and Dec-2014, we enrolled 59 patients with FD unresponsive to firstling therapy with proton pump inhibitors and/or domperidone that underwent OBT before and after 3 months of buspirone (n=32), amitriptyline (n=16) or clebopride (n=11) treatment...
July 12, 2017: Minerva Medica
https://www.readbyqxmd.com/read/28706738/influence-on-adiposity-and-atherogenic-lipaemia-of-fatty-meals-and-snacks-in-daily-life
#9
REVIEW
Antonio Laguna-Camacho
The present work reviewed the connections of changes in consumption of high-fat food with changes in adiposity and lipaemia in adults with overweight or obesity. Hyperlipaemia from higher fat meals and excessive adiposity contributes to atherogenic process. Low-fat diet interventions decrease body fat, lipaemia, and atherosclerosis markers. Inaccuracy of physical estimates of dietary fat intake remains, however, a limit to establishing causal connections. To fill this gap, tracking fat-rich eating episodes at short intervals quantifies the behavioural frequency suggested to measure (by regression of changes in real time) direct effects of this eating pattern on adiposity and atherogenic lipaemia...
2017: Journal of Lipids
https://www.readbyqxmd.com/read/28705610/breeding-protocol-for-the-sand-fly-nyssomyia-neivai-diptera-psychodidae-in-laboratory-conditions
#10
Thais Marchi Goulart, Flávia Benini da Rocha Silva, Vicente Estevam Machado, Wanderson Henrique Cruz Oliveira, Camila Feitosa de Castro, Marili Villa Nova Rodrigues, Mara Cristina Pinto
The information in this protocol covers from the basic steps and material necessary to start a sand fly colony up to the specific details which are important to the success of a Nyssomyia neivai colony. The greatest problems in our colony of Ny. neivai were solved with specific care, for instance, using vermiculite and an adequate number of adults in oviposition containers; the control of fungus with the exact amount of diet for the larvae and humidity control; a second blood meal for females and control of the number of times animals are used for blood meals...
July 11, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28704103/postprandial-dosing-of-bolus-insulin-in-patients-with-type-1-diabetes-a-cross-sectional-study-using-data-from-the-t1d-exchange-registry
#11
Anne Peters, Michelle A Van Name, Brian Larsen Thorsted, Johanne Spanggaard Piltoft, William V Tamborlane
OBJECTIVE: To assess the prevalence and characteristics of patients with type 1 diabetes who dose bolus insulin postprandial (PostP) versus preprandial (PreP). METHODS: Data for this cross-sectional study were obtained from 21,533 participants in the T1D Exchange registry. Data were drawn from the enrollment questionnaire. Patients who dosed 'immediately before meal' or 'several minutes before meal' were classified as PreP. Patients who dosed 'during meal' or 'after meal' were classified as PostP...
July 13, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/28701389/meal-frequency-and-timing-are-associated-with-changes-in-body-mass-index-in-adventist-health-study-2
#12
Hana Kahleova, Jan Irene Lloren, Andrew Mashchak, Martin Hill, Gary E Fraser
Background: Scientific evidence for the optimal number, timing, and size of meals is lacking.Objective: We investigated the relation between meal frequency and timing and changes in body mass index (BMI) in the Adventist Health Study 2 (AHS-2), a relatively healthy North American cohort.Methods: The analysis used data from 50,660 adult members aged ≥30 y of Seventh-day Adventist churches in the United States and Canada (mean ± SD follow-up: 7.42 ± 1.23 y). The number of meals per day, length of overnight fast, consumption of breakfast, and timing of the largest meal were exposure variables...
July 12, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28701300/duodenal-and-ileal-glucose-infusions-differentially-alter-gastrointestinal-peptides-appetite-response-and-food-intake-a-tube-feeding-study
#13
Sally D Poppitt, Hyun Sang Shin, Anne-Thea McGill, Stephanie C Budgett, Kim Lo, Malcolm Pahl, Janice Duxfield, Mark Lane, John R Ingram
Background: Activation of the ileal brake through the delivery of nutrients into the distal small intestine to promote satiety and suppress food intake provides a new target for weight loss. Evidence is limited, with support from naso-ileal lipid infusion studies.Objective: The objective of the study was to investigate whether glucose infused into the duodenum and ileum differentially alters appetite response, food intake, and secretion of satiety-related gastrointestinal peptides.Design: Fourteen healthy male participants were randomly assigned to a blinded 4-treatment crossover, with each treatment of single-day duration...
July 12, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28697609/differential-virulence-and-tsetse-fly-transmissibility-of-i-trypanosoma-congolense-i-and-i-trypanosoma-brucei-i-strains
#14
Purity K Gitonga, Kariuki Ndung'u, Grace A Murilla, Paul C Thande, Florence N Wamwiri, Joanna E Auma, Geoffrey N Ngae, James K Kibugu, Richard Kurgat, John K Thuita
African animal trypanosomiasis causes significant economic losses in sub-Saharan African countries because of livestock mortalities and reduced productivity. Trypanosomes, the causative agents, are transmitted by tsetse flies (Glossina spp.). In the current study, we compared and contrasted the virulence characteristics of five Trypanosoma congolense and Trypanosoma brucei isolates using groups of Swiss white mice (n = 6). We further determined the vectorial capacity of Glossina pallidipes, for each of the trypanosome isolates...
June 27, 2017: Onderstepoort Journal of Veterinary Research
https://www.readbyqxmd.com/read/28697366/circadian-biology-uncoupling-human-body-clocks-by%C3%A2-food-timing
#15
Celine Vetter, Frank A J L Scheer
Synchrony of circadian rhythms between tissues/organs appears critical for health. A new study reports that meal timing, a modifiable temporal cue for the circadian system, can selectively uncouple circadian rhythms in metabolic physiology from the central circadian clock in humans.
July 10, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28696403/preschool-and-school-meal-policies-an-overview-of-what-we-know-about-regulation-implementation-and-impact-on-diet-in-the-uk-sweden-and-australia
#16
REVIEW
Patricia Jane Lucas, Emma Patterson, Gary Sacks, Natassja Billich, Charlotte Elizabeth Louise Evans
School meals make significant contributions to healthy dietary behaviour, at a time when eating habits and food preferences are being formed. We provide an overview of the approaches to the provision, regulation, and improvement of preschool and primary school meals in the UK, Sweden, and Australia, three countries which vary in their degree of centralisation and regulation of school meals. Sweden has a centralised approach; all children receive free meals, and a pedagogical approach to meals is encouraged...
July 11, 2017: Nutrients
https://www.readbyqxmd.com/read/28693964/impact-of-dietary-intake-lifestyle-and-biochemical-factors-on-metabolic-health-in-obese-adolescents
#17
I Aldhoon-Hainerová, V Hainer, H Zamrazilová
BACKGROUND AND AIMS: Obesity devoid of metabolic abnormalities is known as metabolically healthy obesity (MHO). The aim of the study was to examine determinants of MHO during adolescence. METHODS AND RESULTS: From among 710 obese adolescents, 43 girls and 57 boys were classified as metabolically unhealthy (abdominal obesity and ≥2 risk components of metabolic syndrome). MHO (absence of any cardiometabolic risk factor) was found in 211 girls and 131 boys (regardless of waist circumference) and in 33 girls and 27 boys (without abdominal obesity)...
May 15, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/28693962/the-impact-of-triglycerides-on-glucose-tolerance-lipotoxicity-revisited
#18
REVIEW
M Seghieri, D Tricò, A Natali
Elevated plasma triglycerides (TGs) are early key features of conditions associated with a dysregulation in glucose metabolism and may predict the development of type 2 diabetes (T2D) over time. Although the acute ingestion of lipid, either mixed with or shortly before the meal, is neutral or slightly beneficial on glucose tolerance, a short-term increase in plasma TGs induced by either an i.v. lipid infusion or a high-fat diet produces a deterioration of glucose control. Accordingly, chronic lowering of plasma TGs by fibrates improves glucose homeostasis and may also prevent T2D...
July 7, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/28692020/comparative-effectiveness-of-a-portion-controlled-meal-replacement-program-for-weight-loss-in-adults-with-and-without-diabetes-high-blood-sugar
#19
C D Coleman, J R Kiel, A H Mitola, L M Arterburn
BACKGROUND: Individuals with type 2 diabetes (DM2) may be less successful at achieving therapeutic weight loss than their counterparts without diabetes. This study compares weight loss in a cohort of adults with DM2 or high blood sugar (D/HBS) to a cohort of adults without D/HBS. All were overweight/obese and following a reduced or low-calorie commercial weight-loss program incorporating meal replacements (MRs) and one-on-one behavioral support. SUBJECTS/METHODS: Demographic, weight, body composition, anthropometric, pulse and blood pressure data were collected as part of systematic retrospective chart review studies...
July 10, 2017: Nutrition & Diabetes
https://www.readbyqxmd.com/read/28691640/design-of-the-fins-teens-study-a-randomized-controlled-trial-assessing-the-impact-of-fatty-fish-on-cognitive-performance-in-adolescents
#20
Siv Skotheim, Lisbeth Dahl, Katina Handeland, Livar Frøyland, Øyvind Lie, Jannike Øyen, Marian Kjellevold, Kjell Morten Stormark, Ingvild Eide Graff
AIMS: To describe the rationale, study design, population and dietary compliance in a randomized controlled trial (RCT) investigating the effect of fatty fish on cognitive performance and mental health in adolescents. METHOD: In the Fish Intervention Studies-TEENS (FINS-TEENS) study we individually randomized 478 adolescents (14-15-year-olds) from eight secondary schools in Norway to receive school meal lunches with fatty fish or meat or n-3 supplements three times a week for 12 weeks...
July 1, 2017: Scandinavian Journal of Public Health
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