keyword
https://read.qxmd.com/read/38496422/lipopolysaccharide-mediated-effects-of-the-microbiota-on-sleep-and-body-temperature
#1
Eva Szentirmai, Katelin Buckley, Ashley R Massie, Levente Kapas
Background Recent research suggests that microbial molecules translocated from the intestinal lumen into the host's internal environment may play a role in various physiological functions, including sleep. Previously, we identified that butyrate, a short-chain fatty acid, produced by intestinal bacteria, and lipoteichoic acid, a cell wall component of gram-positive bacteria induce sleep when their naturally occurring translocation is mimicked by direct delivery into the portal vein. Building upon these findings, we aimed to explore the sleep signaling potential of intraportally administered lipopolysaccharide, a primary component of gram-negative bacterial cell walls, in rats...
March 5, 2024: Research Square
https://read.qxmd.com/read/38493538/jaboticaba-peel-improves-postprandial-glucose-and-inflammation-a-randomized-controlled-trial-in-adults-with-metabolic-syndrome
#2
JOURNAL ARTICLE
Marina Vilar Geraldi, Ágatta Caroline de Souza, Marina Maintinguer Norde, Paulo Roberto Berni, Lívia Mateus Reguengo, Bruno Geloneze, Mario Roberto Marostica
The modulation of glucose metabolism through dietary sources has been recognized as 1 of the most sustainable approaches for preventing of cardiometabolic diseases. Although fibers and phenolic compounds derived from jaboticaba (Plinia jaboticaba) peel have demonstrated improvements in metabolic pathways in preclinical models, their beneficial effects in clinical trials remain to be fully determined. This study aimed to assess the impact of jaboticaba peel (JP) powder supplementation on glucose metabolism compared with a placebo in individuals with metabolic syndrome (MetS)...
February 28, 2024: Nutrition Research
https://read.qxmd.com/read/38485145/personalising-circadian-hygiene-educational-initiatives-aimed-at-university-students-he-who-has-ears-to-hear-let-him-hear
#3
JOURNAL ARTICLE
Gianluca Giusti, Esther D Domenie, Lisa Zarantonello, Chiara Mangini, Paolo Ferrari, Rodolfo Costa, Sara Montagnese
The aim of the present study was to characterise "early drop-outs" (n = 3185) out of a group of university students (n = 7766) engaged in an ongoing circadian education initiative, to evaluate its efficacy and direct its developments. The initiative is aimed at improving sleep timing/quality through one of two sets of circadian hygiene advice covering the timing of sleep, meals, exercise and light exposure, and it has already been shown to have a positive effect on sleep timing. This second, interim analysis confirmed the high prevalence of disturbed night sleep and social jetlag amongst students at Padova University...
March 14, 2024: Journal of Sleep Research
https://read.qxmd.com/read/38484024/circadian-influences-on-myocardial-ischemia-reperfusion-injury-and-heart-failure
#4
REVIEW
Tobias Eckle, Júlia Bertazzo, Tarak Nath Khatua, Seyed Reza Fatemi Tabatabaei, Naghmeh Moori Bakhtiari, Lori A Walker, Tami A Martino
The impact of circadian rhythms on cardiovascular function and disease development is well established, with numerous studies in genetically modified animals emphasizing the circadian molecular clock's significance in the pathogenesis and pathophysiology of myocardial ischemia and heart failure progression. However, translational preclinical studies targeting the heart's circadian biology are just now emerging and are leading to the development of a novel field of medicine termed circadian medicine. In this review, we explore circadian molecular mechanisms and novel therapies, including (1) intense light, (2) small molecules modulating the circadian mechanism, and (3) chronotherapies such as cardiovascular drugs and meal timings...
March 15, 2024: Circulation Research
https://read.qxmd.com/read/38481208/secretion-of-glucagon-glp-1-and-gip-may-be-affected-by-circadian-rhythm-in-healthy-males
#5
JOURNAL ARTICLE
Dorte B Zilstorff, Michael M Richter, Jens Hannibal, Henrik L Jørgensen, Henriette P Sennels, Nicolai J Wewer Albrechtsen
BACKGROUND: Glucagon is secreted from pancreatic alpha cells in response to low blood glucose and increases hepatic glucose production. Furthermore, glucagon enhances hepatic protein and lipid metabolism during a mixed meal. Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are secreted from gut endocrine cells during meals and control glucose homeostasis by potentiating insulin secretion and inhibiting food intake. Both glucose homeostasis and food intake have been reported to be affected by circadian rhythms and vice versa...
March 14, 2024: BMC Endocrine Disorders
https://read.qxmd.com/read/38479928/effect-of-multicomponent-intervention-on-malnutrition-in-older-adults-a-multicenter-randomized-clinical-trial
#6
RANDOMIZED CONTROLLED TRIAL
Bo Chen, Hongye Zhao, Min Li, Ting Zhao, Ruoqi Liao, Jun Lu, Yanzheng Zou, Junlan Tu, Xinran Teng, Yaxuan Huang, Jin Liu, Peng Huang, Jianqing Wu
BACKGROUND & AIMS: Malnutrition is a significant geriatric syndrome (GS) prevalent in older adults and seriously affects patient prognosis and quality of life. We assessed the impact of the multicomponent intervention of health education, dietary advice, and exercise with oral nutritional supplementation (ONS) on nutritional status, body composition, physical functions, and quality of life. METHODS: This multicenter randomized clinical trial (RCT) was performed from April 2021 to April 2022...
April 2024: Clinical Nutrition ESPEN
https://read.qxmd.com/read/38479908/association-of-largest-meal-timing-and-eating-frequency-with-body-mass-index-and-obesity
#7
JOURNAL ARTICLE
Giovana Longo-Silva, Márcia de Oliveira Lima, Anny Kariny Pereira Pedrosa, Renan Serenini, Patricia de Menezes Marinho, Risia Cristina Egito de Menezes
BACKGROUND AND AIMS: The circadian pattern of eating behaviors has garnered increasing interest as a strategy for obesity prevention and weight loss. It is believed that the benefits stem from aligning food intake with the body's natural daily rhythms. However, the existing body of evidence is limited in scale and scope and there has been insufficient evaluation of temporal eating behaviors, such as the specific time of day in which the highest calorie consumption occurs, meal frequency, and distribution...
April 2024: Clinical Nutrition ESPEN
https://read.qxmd.com/read/38479470/shades-and-shifts-in-flexitarian-and-meat-oriented-consumer-profiles-in-a-german-panel-study
#8
JOURNAL ARTICLE
Anna-Maria Strässner, Werner Wirth
Consumers' growing awareness of the adverse effects of high meat consumption has led to increased attention to flexitarian or meat-reduced diets. However, most flexitarians do not significantly reduce their meat consumption and still eat many meat-based meals. This study aims to classify the large and heterogeneous consumer group of flexitarians into different profiles based on attitudinal, normative, and control beliefs about meat reduction. Being aware that consumer profiles can change over time, this study explores the dynamics of the identified profiles using a two-wave panel survey of 430 German consumers...
March 11, 2024: Appetite
https://read.qxmd.com/read/38477893/circadian-patterns-of-behaviour-change-during-pregnancy-in-mice
#9
JOURNAL ARTICLE
Georgia S Clarke, Andrew D Vincent, Sharon R Ladyman, Kathryn L Gatford, Amanda J Page
Food intake and activity adapt during pregnancy to meet the increased energy demands. In comparison to non-pregnant females, pregnant mice consume more food, eating larger meals during the light phase, and reduce physical activity. How pregnancy changes the circadian timing of behaviour was less clear. We therefore randomised female C57BL/6J mice to mating for study until early (n = 10), mid- (n = 10) or late pregnancy (n = 11) or as age-matched, non-pregnant controls (n = 12)...
March 13, 2024: Journal of Physiology
https://read.qxmd.com/read/38475777/a-study-on-the-influencing-factors-of-mental-health-of-chinese-garden-workers-a-cross-sectional-study
#10
JOURNAL ARTICLE
Yujin Xie, Yang Jiao, Lei Shi, Di Liu, Ying Liu, Zhen Tang, Weijun Gong, Hong Yu, Yuanshuo Ma
BACKGROUND: Occupational hazards occur in all walks of life. China's horticulture industry is undergoing rapid development. However, the mental health of garden workers has not received much attention. This study investigates the mental health status and influencing factors of Chinese garden workers and provides a basis for promoting their mental health and ensuring the healthy development of Chinese horticulture. METHODS: A cross-sectional survey of garden workers in Beijing was conducted from 10 July 2021 to 10 October 2021...
March 12, 2024: BMC Public Health
https://read.qxmd.com/read/38474850/chrononutrition-in-the-prevention-and-management-of-metabolic-disorders-a-literature-review
#11
REVIEW
Maria Mentzelou, Sousana K Papadopoulou, Evmorfia Psara, Gavriela Voulgaridou, Eleni Pavlidou, Odysseas Androutsos, Constantinos Giaginis
BACKGROUND: The concept of time-restricted eating (TRE) or time-restricted feeding (TRF) promotes daily periods of feeding and fasting to determine whole-body physiology. Chronic misalignment of circadian rhythms or chrono-disruption is related to an increased risk of diverse metabolic disorders. The progression of non-communicable diseases seems to be affected by the timing of meals. As a result, intermittent fasting is a promising approach for their management. The aim of the present literature review is to examine and scrutinize the TRE protocols in the fields of prevention and management of metabolic disorders...
March 1, 2024: Nutrients
https://read.qxmd.com/read/38474753/postprandial-micronutrient-variability-and-bioavailability-an-interventional-meal-study-in-young-vs-old-participants
#12
JOURNAL ARTICLE
Denny Pellowski, Paula Kusch, Thorsten Henning, Bastian Kochlik, Maria Maares, Amy Schmiedeskamp, Gabriele Pohl, Monika Schreiner, Susanne Baldermann, Hajo Haase, Tanja Schwerdtle, Tilman Grune, Daniela Weber
This study explores age- and time-dependent variations in postprandial micronutrient absorption after a micronutrient-rich intervention meal within the Biomiel (bioavailability of micronutrients in elderly) study. Comprising 43 healthy participants, the study compares young (n = 21; mean age 26.90 years) and old (n = 22; mean age 66.77 years) men and women, analyzing baseline concentrations and six-hour postprandial dynamics of iron (Fe), copper (Cu), zinc (Zn), selenium (Se), iodine (I), free zinc (fZn), vitamin C, retinol, lycopene, β-carotene, α-tocopherol, and γ-tocopherol, along with 25(OH) vitamin D (quantified only at baseline)...
February 23, 2024: Nutrients
https://read.qxmd.com/read/38474714/impact-of-a-food-skills-course-with-a-teaching-kitchen-on-dietary-and-cooking-self-efficacy-and-behaviors-among-college-students
#13
JOURNAL ARTICLE
Caitlin D French, Alexander Gomez-Lara, Arianna Hee, Akshara Shankar, Nayoung Song, Monserrath Campos, Mikelle McCoin, Susana L Matias
College students may face barriers to eating healthy foods. Educational interventions providing practical knowledge and skills may help students to overcome financial barriers or other barriers to acquiring, preparing, and consuming healthy foods. We evaluated the association between participation in a semester-long food skills course with an interactive teaching kitchen and dietary and cooking self-efficacy and behaviors. Participants were recruited from course enrollees (intervention) and the general student population (comparison)...
February 21, 2024: Nutrients
https://read.qxmd.com/read/38472010/chrononutrition-in-traditional-european-medicine-ideal-meal-timing-for-cardiometabolic-health-promotion
#14
REVIEW
Nora Selena Eberli, Ludivine Colas, Anne Gimalac
Meal timing plays a crucial role for cardiometabolic health, given the circadian regulation of cardiometabolic function. However, to the best of our knowledge, no concept of meal timing exists in traditional European medicine (TEM). Therefore, in this narrative review, we aim to define the optimal time slot for energy intake and optimal energy distribution throughout the day in a context of TEM and explore further implications. By reviewing literature published between 2002 and 2022, we found that optimal timing for energy intake may be between 06:00 and 09:00, 12:00 and 14:00, and between 15:00 and 18:00, with high energy breakfast, medium energy lunch and low energy dinner and possibly further adjustments according to one's chronotype and genetics...
March 1, 2024: Journal of Integrative Medicine
https://read.qxmd.com/read/38467383/thoracoabdominal-wall-motion-guided-biofeedback-treatment-of-abdominal-distension-a-randomized-placebo-controlled-trial
#15
JOURNAL ARTICLE
Elizabeth Barba, Dan M Livovsky, Anna Accarino, Fernando Azpiroz
BACKGROUND AND AIMS: Abdominal distention results from abdominophrenic dyssynergia (diaphragmatic contraction and abdominal wall relaxation) in patients with disorders of the gut-brain interaction. This study aimed to validate a simple biofeedback procedure, guided by abdominothoracic wall motion, for treating abdominal distension. METHODS: In this randomized, parallel, placebo-controlled trial, 42 consecutive patients (36 women and 6 men; age, 17-64 years) with meal-triggered visible abdominal distension were recruited...
March 9, 2024: Gastroenterology
https://read.qxmd.com/read/38466479/norovirus-gii-17-caused-five-outbreaks-linked-to-frozen-domestic-bilberries-in-finland-2019
#16
JOURNAL ARTICLE
Maija Summa, Enni Tuutti, Haider Al-Hello, Liisa-Maija Huttunen, Ruska Rimhanen-Finne
In March 2019, the Finnish Institute for Health and Welfare and Finnish Food Authority started an outbreak investigation after a notification of food business operators' recall of frozen bilberries due to a norovirus finding. A retrospective search was conducted in the food and waterborne outbreak notification system to identify the notifications linked to norovirus and consumption of bilberries in January-March 2019. Five outbreaks were found in which norovirus GII or GII.17 had been detected in patient samples...
March 11, 2024: Food and Environmental Virology
https://read.qxmd.com/read/38460943/continuous-glucose-monitoring-guided-insulin-administration-in-long-term-care-facilities-a-randomized-clinical-trial
#17
JOURNAL ARTICLE
Thaer Idrees, Iris Castro, Hyungseok D Oh, Monica D Gavaller, Zohyra Zabala, Emmelin Moreno, Bobak Moazzami, Rodolfo J Galindo, Priyathama Vellanki, Elena Cabb, Theodore M Johnson, Limin Peng, Guillermo E Umpierrez
OBJECTIVES: To evaluate the efficacy of real-time continuous glucose monitoring (rt-CGM) in adjusting insulin therapy in long-term care facilities (LTCF). DESIGN: Prospective randomized clinical trial. SETTINGS AND PARTICIPANTS: Insulin-treated patients with type 2 diabetes (T2D) admitted to LTCF. METHODS: Participants in the standard of care wore a blinded CGM with treatment adjusted based on point-of-care capillary glucose results before meals and bedtime (POC group)...
March 6, 2024: Journal of the American Medical Directors Association
https://read.qxmd.com/read/38460445/sex-differences-in-the-relationships-between-macronutrients-and-all-cause-mortality-in-individuals-with-metabolically-unhealthy-overweight-obesity
#18
JOURNAL ARTICLE
Jiaqi Zhang, Tong Xu, Yingxiang Huang, Runhong Li, Kaiyuan Wang, Xinli Lin, Lina Jin
This study investigates sex differences on the effects of macronutrient quantity, quality, and timing on mortality in metabolically unhealthy overweight/obesity (MUO) populations. The study included 18,345 participants, including 9204 men and 9141 women. The Cox proportional risk model and isocaloric substitution effects were used to examine the association of macronutrient intake and subtype with all-cause mortality in the MUO populations. After adjusting for the potential covariates, The risk of all-cause mortality was elevated in men in the highest 25% percentile of poor-quality carbohydrates compared with men in the lowest quartile (odds ratio [OR]: 2...
February 11, 2024: Nutrition
https://read.qxmd.com/read/38460262/recovery-of-perfluorooctane-sulfonate-pfos-and-perfluorooctanoate-pfoa-from-water-using-foam-fractionation-with-whey-soy-protein
#19
JOURNAL ARTICLE
Nan Hu, Xiaodan Sun, Nan Yao, Mei Yang, Yaoxi Chen, Zhijun Zhang
Perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) are persistent anthropogenic chemicals that are widely distributed in the environment and pose significant risks to human health. Foam fractionation has emerged as a promising method to recover PFOS/PFOA from water. However, PFOS/PFOA concentrations in wastewater are often inadequate to generate stable foams due to their high critical micelle concentrations and the addition of a cosurfactant is necessary. In this study, we developed whey soy protein (WSP) as a green frother and collector derived from soybean meal (SBM), which is an abundant and cost-effective agro-industrial residue...
March 7, 2024: Journal of Hazardous Materials
https://read.qxmd.com/read/38458859/pioneering-new-frontiers-in-circadian-medicine-chronotherapies-for-cardiovascular-health
#20
REVIEW
Ifene David Festus, Jeri Spilberg, Martin E Young, Sean Cain, Sepideh Khoshnevis, Michael H Smolensky, Fariya Zaheer, Giannina Descalzi, Tami A Martino
Cardiovascular disease (CVD) is a global health concern. Circadian medicine improves cardiovascular care by aligning treatments with our body's daily rhythms and their underlying cellular circadian mechanisms. Time-based therapies, or chronotherapies, show special promise in clinical cardiology. They optimize treatment schedules for better outcomes with fewer side effects by recognizing the profound influence of rhythmic body cycles. In this review, we focus on three chronotherapy areas (medication, light, and meal timing) with potential to enhance cardiovascular care...
March 7, 2024: Trends in Endocrinology and Metabolism: TEM
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