keyword
MENU ▼
Read by QxMD icon Read
search

Adaptive switch

keyword
https://www.readbyqxmd.com/read/28334152/repeated-and-diverse-losses-of-corolla-bilateral-symmetry-in-the-lamiaceae
#1
Jinshun Zhong, Jill C Preston, Lena C Hileman, Elizabeth A Kellogg
Background and Aims: Independent evolution of derived complex characters provides a unique opportunity to assess whether and how similar genetic changes correlate with morphological convergence. Bilaterally symmetrical corollas have evolved multiple times independently from radially symmetrical ancestors and likely represent adaptations to attract specific pollinators. On the other hand, losses of bilateral corolla symmetry have occurred sporadically in various groups, due to either modification of bilaterally symmetrical corollas in late development or early establishment of radial symmetry...
March 1, 2017: Annals of Botany
https://www.readbyqxmd.com/read/28332646/the-role-of-animal-reservoirs-in-social-environmental-landscapes-remarks-on-the-control-of-avian-influenza-and-preparedness-for-pandemics
#2
M P Ortiz-Rodríguez, G C Ramírez-Nieto, L C Villamil-Jiménez
Influenza viruses are well known for their ability to infect and cause disease in a broad range of hosts. Modern advances in reverse genetics have enabled scientists to probe the mutations that allow influenza viruses to perform host switching. Despite this detailed understanding of the molecular modifications that allow host switching and adaptation, there is a gap in knowledge regarding the factors external to the virus and their interactions that act as triggers leading to a pandemic. Studies on the ecology of zoonotic pathogens should be the new paradigm for understanding not only influenza viruses but any other infectious disease that can be a threat to animal and human health...
December 2016: Revue Scientifique et Technique
https://www.readbyqxmd.com/read/28332274/time-course-expression-qtl-atlas-of-the-global-transcriptional-response-of-wheat-to-fusarium-graminearum
#3
Mina Samad-Zamini, Wolfgang Schweiger, Thomas Nussbaumer, Klaus F X Mayer, Hermann Buerstmayr
Fusarium head blight is a devastating disease of small grain cereals such as bread wheat (Triticum aestivum). The pathogen switches from a biotrophic to a nectrotrophic lifestyle in course of disease development forcing its host to adapt its defence strategies. Using a genetical genomics approach we illustrate genome-wide reconfigurations of genetic control over transcript abundances between two decisive time points after inoculation with the causative pathogen Fusarium graminearum. Whole transcriptome measurements have been recorded for 163 lines of a wheat doubled haploid population segregating for several resistance genes yielding 15 552 at 30 hours and 15 888 eQTL at 50 hours after inoculation...
March 23, 2017: Plant Biotechnology Journal
https://www.readbyqxmd.com/read/28326042/examining-the-roles-of-reasoning-and-working-memory-in-predicting-casual-game-performance-across-extended-gameplay
#4
Michael B Kranz, Pauline L Baniqued, Michelle W Voss, Hyunkyu Lee, Arthur F Kramer
The variety and availability of casual video games presents an exciting opportunity for applications such as cognitive training. Casual games have been associated with fluid abilities such as working memory (WM) and reasoning, but the importance of these cognitive constructs in predicting performance may change across extended gameplay and vary with game structure. The current investigation examined the relationship between cognitive abilities and casual game performance over time by analyzing first and final session performance over 4-5 weeks of game play...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28325760/neisseria-meningitidis-uses-sibling-small-regulatory-rnas-to-switch-from-cataplerotic-to-anaplerotic-metabolism
#5
Yvonne Pannekoek, Robert A G Huis In 't Veld, Kim Schipper, Sandra Bovenkerk, Gertjan Kramer, Matthijs C Brouwer, Diederik van de Beek, Dave Speijer, Arie van der Ende
Neisseria meningitidis (the meningococcus) is primarily a commensal of the human oropharynx that sporadically causes septicemia and meningitis. Meningococci adapt to diverse local host conditions differing in nutrient supply, like the nasopharynx, blood, and cerebrospinal fluid, by changing metabolism and protein repertoire. However, regulatory transcription factors and two-component systems in meningococci involved in adaptation to local nutrient variations are limited. We identified novel sibling small regulatory RNAs ( Neisseriametabolic switch regulators [NmsRs]) regulating switches between cataplerotic and anaplerotic metabolism in this pathogen...
March 21, 2017: MBio
https://www.readbyqxmd.com/read/28321188/explicit-action-switching-interferes-with-the-context-specificity-of-motor-memories-in-older-adults
#6
Carly J Sombric, Harrison M Harker, Patrick J Sparto, Gelsy Torres-Oviedo
Healthy aging impairs the ability to adapt movements to novel situations and to switch choices according to the context in cognitive tasks, indicating resistance to changes in motor and cognitive behaviors. Here we examined if this lack of "flexibility" in old subjects observed in motor and cognitive domains were related. To this end, we evaluated subjects' performance in a motor task that required switching walking patterns and its relation to performance in a cognitive switching task. Specifically, a group of old (>73 years old) and young subjects learned a new locomotor pattern on a split-belt treadmill, which drives the legs at different speeds...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28320944/negative-allosteric-regulation-of-enterococcus-faecalis-small-alarmone-synthetase-relq-by-single-stranded-rna
#7
Jelena Beljantseva, Pavel Kudrin, Liis Andresen, Victoria Shingler, Gemma C Atkinson, Tanel Tenson, Vasili Hauryliuk
The alarmone nucleotides guanosine pentaphosphate (pppGpp) and tetraphosphate (ppGpp), collectively referred to as (p)ppGpp, are key regulators of bacterial growth, stress adaptation, pathogenicity, and antibiotic tolerance. We show that the tetrameric small alarmone synthetase (SAS) RelQ from the Gram-positive pathogen Enterococcus faecalis is a sequence-specific RNA-binding protein. RelQ's enzymatic and RNA binding activities are subject to intricate allosteric regulation. (p)ppGpp synthesis is potently inhibited by the binding of single-stranded RNA...
March 20, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28320680/data-driven-multiagent-systems-consensus-tracking-using-model-free-adaptive-control
#8
Xuhui Bu, Zhongsheng Hou, Hongwei Zhang
This paper investigates the data-driven consensus tracking problem for multiagent systems with both fixed communication topology and switching topology by utilizing a distributed model free adaptive control (MFAC) method. Here, agent's dynamics are described by unknown nonlinear systems and only a subset of followers can access the desired trajectory. The dynamical linearization technique is applied to each agent based on the pseudo partial derivative, and then, a distributed MFAC algorithm is proposed to ensure that all agents can track the desired trajectory...
March 14, 2017: IEEE Transactions on Neural Networks and Learning Systems
https://www.readbyqxmd.com/read/28320274/brain-mitochondrial-subproteome-of-rpn10-binding-proteins-and-its-changes-induced-by-the-neurotoxin-mptp-and-the-neuroprotector-isatin
#9
A E Medvedev, O A Buneeva, A T Kopylov, O V Tikhonova, M V Medvedeva, L N Nerobkova, I G Kapitsa, V G Zgoda
Mitochondria play an important role in molecular mechanisms of neuroplasticity, adaptive changes of the brain that occur in the structure and function of its cells in response to altered physiological conditions or development of pathological disorders. Mitochondria are a crucial target for actions of neurotoxins, causing symptoms of Parkinson's disease in various experimental animal models, and also neuroprotectors. Good evidence exists in the literature that mitochondrial dysfunction induced by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) influences functioning of the ubiquitin-proteasomal system (UPS) responsible for selective proteolytic degradation of proteins from various intracellular compartments (including mitochondria), and neuroprotective effects of certain antiparkinsonian agents (monoamine oxidase inhibitors) may be associated with their effects on UPS...
March 2017: Biochemistry. Biokhimii︠a︡
https://www.readbyqxmd.com/read/28303712/lithium-metal-anodes-with-an-adaptive-solid-liquid-interfacial-protective-layer
#10
Kai Liu, Allen Pei, Hye Ryoung Lee, Biao Kong, Nian Liu, Dingchang Lin, Yayuan Liu, Chong Liu, Po-Chun Hsu, Zhenan Bao, Yi Cui
Lithium metal is an attractive anode for the next generation of high energy density lithium-ion batteries due to its high specific capacity (3,860 mAh/g) and the lowest anode potential of all. However, the key issue is that the static solid electrolyte interphase cannot match the dynamic volume changes of the Li anode, resulting in side reactions, dendrite growth, and poor electrodeposition behavior which prevent its practical applications. Here, we show that the "solid-liquid" hybrid behavior of a dynamically-crosslinked polymer enables its use as an excellent adaptive interfacial layer for Li metal anodes...
March 17, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28303100/a-neural-dynamic-architecture-for-reaching-and-grasping-integrates-perception-and-movement-generation-and-enables-on-line-updating
#11
Guido Knips, Stephan K U Zibner, Hendrik Reimann, Gregor Schöner
Reaching for objects and grasping them is a fundamental skill for any autonomous robot that interacts with its environment. Although this skill seems trivial to adults, who effortlessly pick up even objects they have never seen before, it is hard for other animals, for human infants, and for most autonomous robots. Any time during movement preparation and execution, human reaching movement are updated if the visual scene changes (with a delay of about 100 ms). The capability for online updating highlights how tightly perception, movement planning, and movement generation are integrated in humans...
2017: Frontiers in Neurorobotics
https://www.readbyqxmd.com/read/28293210/integration-of-advance-information-about-a-forthcoming-task-switch-evidence-from-eye-blink-rates
#12
Thomas Kleinsorge, Juliane Scheil
We investigated task switching among four tasks by means of a modified cuing procedure with two types of cues. One type of cue consisted of a standard task cue indicating the next task. In half of the trials, this task cue was preceded by another type of cue that reduced the set of candidate tasks from four to two tasks. In addition, we measured participants' spontaneous eye blink rates (EBRs) at the beginning, in the middle, and at the end of the experiment. Whereas interindividual differences in mean EBR had no pronounced effect on task switching performance, changes in EBRs during the first half of the experiment significantly modulated the interaction of the effects of the two types of cues...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28291524/more-than-just-channeling-the-role-of-subcortical-mechanisms-in-executive-functions-evidence-from-the-stroop-task
#13
William Saban, Shai Gabay, Eyal Kalanthroff
The literature has long emphasized the role of the cerebral cortex in executive functions. Recently, however, several researchers have suggested that subcortical areas might also be involved in executive functions. The current study explored the possibility that subcortical mechanisms have a functional role in adaptive resolution of Stroop interference. We asked 20 participants to complete a cued task-switching Stroop task with variable cue-target intervals (CTI). Using a stereoscope, we manipulated which eye was shown the relevant dimension and which was shown the irrelevant dimension...
March 10, 2017: Acta Psychologica
https://www.readbyqxmd.com/read/28291393/early-positron-emission-tomography-response-adapted-treatment-in-stage-i-and-ii-hodgkin-lymphoma-final-results-of-the-randomized-eortc-lysa-fil-h10-trial
#14
Marc P E André, Théodore Girinsky, Massimo Federico, Oumédaly Reman, Catherine Fortpied, Manuel Gotti, Olivier Casasnovas, Pauline Brice, Richard van der Maazen, Alessandro Re, Véronique Edeline, Christophe Fermé, Gustaaf van Imhoff, Francesco Merli, Réda Bouabdallah, Catherine Sebban, Lena Specht, Aspasia Stamatoullas, Richard Delarue, Valeria Fiaccadori, Monica Bellei, Tiana Raveloarivahy, Annibale Versari, Martin Hutchings, Michel Meignan, John Raemaekers
Purpose Patients who receive combined modality treatment for stage I and II Hodgkin lymphoma (HL) have an excellent outcome. Early response evaluation with positron emission tomography (PET) scan may improve selection of patients who need reduced or more intensive treatments. Methods We performed a randomized trial to evaluate treatment adaptation on the basis of early PET (ePET) after two cycles of doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD) in previously untreated-according to European Organisation for Research and Treatment of Cancer criteria favorable (F) and unfavorable (U)-stage I and II HL...
March 14, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28288164/bayesian-model-of-signal-rewiring-reveals-mechanisms-of-gene-dysregulation-in-acquired-drug-resistance-in-breast-cancer
#15
A K M Azad, Alfons Lawen, Jonathan M Keith
Small molecule inhibitors, such as lapatinib, are effective against breast cancer in clinical trials, but tumor cells ultimately acquire resistance to the drug. Maintaining sensitization to drug action is essential for durable growth inhibition. Recently, adaptive reprogramming of signaling circuitry has been identified as a major cause of acquired resistance. We developed a computational framework using a Bayesian statistical approach to model signal rewiring in acquired resistance. We used the p1-model to infer potential aberrant gene-pairs with differential posterior probabilities of appearing in resistant-vs-parental networks...
2017: PloS One
https://www.readbyqxmd.com/read/28287403/rankl-coordinates-multiple-osteoclastogenic-pathways-by-regulating-expression-of-ubiquitin-ligase-rnf146
#16
Yoshinori Matsumoto, Jose Larose, Oliver A Kent, Melissa Lim, Adele Changoor, Lucia Zhang, Yaryna Storozhuk, Xiaohong Mao, Marc D Grynpas, Feng Cong, Robert Rottapel
Bone undergoes continuous remodeling due to balanced bone formation and resorption mediated by osteoblasts and osteoclasts, respectively. Osteoclasts arise from the macrophage lineage, and their differentiation is dependent on RANKL, a member of the TNF family of cytokines. Here, we have provided evidence that RANKL controls the expression of 3BP2, an adapter protein that is required for activation of SRC tyrosine kinase and simultaneously coordinates the attenuation of β-catenin, both of which are required to execute the osteoclast developmental program...
March 13, 2017: Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28286708/transcriptomic-analysis-reveals-metabolic-switches-and-surface-remodeling-as-key-processes-for-stage-transition-in-trypanosoma-cruzi
#17
Luisa Berná, Maria Laura Chiribao, Gonzalo Greif, Matias Rodriguez, Fernando Alvarez-Valin, Carlos Robello
American trypanosomiasis is a chronic and endemic disease which affects millions of people. Trypanosoma cruzi, its causative agent, has a life cycle that involves complex morphological and functional transitions, as well as a variety of environmental conditions. This requires a tight regulation of gene expression, which is achieved mainly by post-transcriptional regulation. In this work we conducted an RNAseq analysis of the three major life cycle stages of T. cruzi: amastigotes, epimastigotes and trypomastigotes...
2017: PeerJ
https://www.readbyqxmd.com/read/28285156/the-role-of-cognition-for-different-stages-of-visuomotor-adaptation-in-younger-and-older-adults
#18
Anja Simon, Otmar Bock
A recent model identified three stages of learning, the first drawing on cognitive flexibility, the second on inhibition, and the third on automation. We explored the validity of this model for visuomotor learning and found that adaptation is associated with inhibition early during adaptation and with automaticity later on. An initial association with cognitive flexibility remained inconclusive. This work employs another marker of cognitive flexibility and extends our work to older adults. Twenty young and 20 older adults completed three cognitive tasks (switch task, Stroop task and four-choice-reaction-time-task)...
March 8, 2017: Human Movement Science
https://www.readbyqxmd.com/read/28280580/organization-of-biogeochemical-nitrogen-pathways-with-switch-like-adjustment-in-fluctuating-soil-redox-conditions
#19
Sanjay Lamba, Soumen Bera, Mubasher Rashid, Alexander B Medvinsky, Gui-Quan Sun, Claudia Acquisti, Amit Chakraborty, Bai-Lian Li
Nitrogen is cycled throughout ecosystems by a suite of biogeochemical processes. The high complexity of the nitrogen cycle resides in an intricate interplay between reversible biochemical pathways alternatively and specifically activated in response to diverse environmental cues. Despite aggressive research, how the fundamental nitrogen biochemical processes are assembled and maintained in fluctuating soil redox conditions remains elusive. Here, we address this question using a kinetic modelling approach coupled with dynamical systems theory and microbial genomics...
January 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28278471/a-geometric-model-for-specularity-prediction-on-planar-surfaces-with-multiple-light-sources
#20
Alexandre Morgand, Mohamed Tamaazousti, Adrien Bartoli
Specularities are often problematic in computer vision since they impact the dynamic range of the image intensity. A natural approach would be to predict and discard them using computer graphics models. However, these models depend on parameters which are difficult to estimate (light sources, objects' material properties and camera). We present a geometric model called JOLIMAS: JOint LIght-MAterial Specularity, which predicts the shape of specularities. JOLIMAS is reconstructed from images of specularities observed on a planar surface...
March 2, 2017: IEEE Transactions on Visualization and Computer Graphics
keyword
keyword
2208
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"