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https://www.readbyqxmd.com/read/28103558/effective-multi-query-expansions-collaborative-deep-networks-based-feature-learning-for-robust-landmark-retrieval
#1
Yang Wang, Xuemin Lin, Lin Wu, Wenjie Zhang
Given a query photo issued by a user (q-user), the landmark retrieval is to return a set of photos with their landmarks similar to those of the query, while the existing studies on the landmark retrieval focus on exploiting geometries of landmarks for similarity matches between candidate photos and a query photo. We observe that the same landmarks provided by different users over social media community may convey different geometry information depending on the viewpoints and/or angles, and may subsequently yield very different results...
January 18, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28103555/robust-head-pose-estimation-based-on-partially-latent-mixture-of-linear-regressions
#2
Vincent Drouard, Radu Horaud, Antoine Deleforge, Sileye Ba, Georgios Evangelidis
Head-pose estimation has many applications, such as social event analysis, human-robot and human-computer interaction, driving assistance, and so forth. Head-pose estimation is challenging because it must cope with changing illumination conditions, variabilities in face orientation and in appearance, partial occlusions of facial landmarks, as well as bounding-box-to- face alignment errors. We propose tu use a mixture of linear regressions with partially-latent output. This regression method learns to map high-dimensional feature vectors (extracted from bounding boxes of faces) onto the joint space of head-pose angles and bounding-box shifts, such that they are robustly predicted in the presence of unobservable phenomena...
January 16, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28102755/anionic-lipids-and-the-maintenance-of-membrane-electrostatics-in-eukaryotes
#3
Matthieu Pierre Platre, Yvon Jaillais
A wide range of signaling processes occurs at the cell surface through the reversible association of proteins from the cytosol to the plasma membrane. Some low abundant lipids are enriched at the membrane of specific compartments and thereby contribute to the identity of cell organelles by acting as biochemical landmarks. Lipids also influence membrane biophysical properties, which emerge as an important feature in specifying cellular territories. Such parameters are crucial for signal transduction and include lipid packing, membrane curvature and electrostatics...
January 19, 2017: Plant Signaling & Behavior
https://www.readbyqxmd.com/read/28102030/impact-of-sodium-glucose-cotransporter-2-inhibitors-on-nonglycemic-outcomes-in-patients-with-type-2-diabetes
#4
Jennifer M Trujillo, Wesley A Nuffer
The efficacy of the sodium-glucose cotransporter 2 (SGLT2) inhibitors canagliflozin, dapagliflozin, and empagliflozin in reducing hyperglycemia in patients with type 2 diabetes is well documented. In addition, positive effects have been observed with these agents on nonglycemic variables, such as reductions in body weight and blood pressure, which may confer additional health benefits. SGLT2 inhibitors are also associated with evidence of renal-protecting benefits. Furthermore, during the landmark Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes (EMPA-REG OUTCOME) trial, a substantial reduction in major adverse cardiovascular outcomes was demonstrated with empagliflozin therapy...
January 19, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28101648/the-limits-of-boundaries-unpacking-localization-and-cognitive-mapping-relative-to-a-boundary
#5
Ruojing Zhou, Weimin Mou
Previous research (Zhou, Mou, Journal of Experimental Psychology: Learning, Memory and Cognition 42(8):1316-1323, 2016) showed that learning individual locations relative to a single landmark, compared to learning relative to a boundary, led to more accurate inferences of inter-object spatial relations (cognitive mapping of multiple locations). Following our past findings, the current study investigated whether the larger number of reference points provided by a homogeneous circular boundary, as well as less accessible knowledge of direct spatial relations among the multiple reference points, would lead to less effective cognitive mapping relative to the boundary...
January 19, 2017: Psychological Research
https://www.readbyqxmd.com/read/28100525/transoesophageal-echocardiographic-evaluation-of-central-venous-catheter-positioning-using-peres-formula-or-a-radiological-landmark-based-approach-a-prospective-randomized-single-centre-study
#6
J H Ahn, I S Kim, J H Yang, I G Lee, D H Seo, S P Kim
BACKGROUND: The lower superior vena cava (SVC), near its junction with the right atrium (RA), is considered the ideal location for the central venous catheter tip to ensure proper function and prevent injuries. We determined catheter insertion depth with a new formula using the sternoclavicular joint and the carina as radiological landmarks, with a 1.5 cm safety margin. The accuracy of tip positioning with the radiological landmark-based technique (R) and Peres' formula (P) was compared using transoesophageal echocardiography...
February 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/28099958/distance-from-left-renal-vein-to-inferior-pancreaticoduodenal-artery-a-landmark-for-identifying-inferior-pancreaticoduodenal-artery-in-pancreatoduodenectomy
#7
Yoshito Tomimaru, Kaishu Tanaka, Kozo Noguchi, Hisanori Hatano, Hidetoshi Eguchi, Keizo Dono
BACKGROUND/AIM: During pancreatoduodenectomy, early ligation of major afferent arteries to pancreatic head prior to dissection of the corresponding veins may reduce intraoperative bleeding. Inferior pancreaticoduodenal artery (IPDA), one of the major afferent arteries, is difficult to identify. We measured the distance from left renal vein to IPDA based on preoperative multi-detector row computed tomography (MDCT) images for use as a new landmark for IPDA. METHODS: The distance between left renal vein and IPDA was measured in 417 patients using MDCT images...
January 19, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28099304/three-dimensional-analysis-of-acute-scaphoid-fracture-displacement-proximal-extension-deformity-of-the-scaphoid
#8
Yonatan Schwarcz, Yael Schwarcz, Eran Peleg, Leo Joskowicz, Ronit Wollstein, Shai Luria
BACKGROUND: Our goal was to analyze the movement of acute scaphoid waist fracture fragments and adjacent bones in a common coordinate system. Our hypothesis was that the distal scaphoid fragment flexes and pronates and the proximal fragment extends. METHODS: Computed tomography (CT) scans of patients diagnosed with an acute scaphoid waist fracture were evaluated using a 3-dimensional (3D) model. The scans of 57 nondisplaced and 23 displaced fractures were compared with a control group of 27 scans showing no pathological involvement of the wrist...
January 18, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28098771/breast-cancer-brain-metastases-clonal-evolution-in-clinical-context
#9
REVIEW
Jodi M Saunus, Amy E McCart Reed, Zhun Leong Lim, Sunil R Lakhani
Brain metastases are highly-evolved manifestations of breast cancer arising in a unique microenvironment, giving them exceptional adaptability in the face of new extrinsic pressures. The incidence is rising in line with population ageing, and use of newer therapies that stabilise metastatic disease burden with variable efficacy throughout the body. Historically, there has been a widely-held view that brain metastases do not respond to circulating therapeutics because the blood-brain-barrier (BBB) restricts their uptake...
January 13, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28098480/regression-spline-mixed-models-for-testing-meaningful-landmarks-in-time-series-data
#10
Karen E Nielsen, Richard Gonzalez
No abstract text is available yet for this article.
January 18, 2017: Multivariate Behavioral Research
https://www.readbyqxmd.com/read/28098306/effective-viscosity-and-dynamics-of-spreading-epithelia-a-solvable-model
#11
C Blanch-Mercader, R Vincent, E Bazellières, X Serra-Picamal, X Trepat, J Casademunt
Collective cell migration in spreading epithelia in controlled environments has become a landmark in our current understanding of fundamental biophysical processes in development, regeneration, wound healing or cancer. Epithelial monolayers are treated as thin layers of a viscous fluid that exert active traction forces on the substrate. The model is exactly solvable and shows a broad range of applicabilities for the quantitative analysis and interpretation of force microscopy data of monolayers from a variety of experiments and cell lines...
January 18, 2017: Soft Matter
https://www.readbyqxmd.com/read/28097213/fully-automated-quantitative-cephalometry-using-convolutional-neural-networks
#12
Sercan Ö Arık, Bulat Ibragimov, Lei Xing
Quantitative cephalometry plays an essential role in clinical diagnosis, treatment, and surgery. Development of fully automated techniques for these procedures is important to enable consistently accurate computerized analyses. We study the application of deep convolutional neural networks (CNNs) for fully automated quantitative cephalometry for the first time. The proposed framework utilizes CNNs for detection of landmarks that describe the anatomy of the depicted patient and yield quantitative estimation of pathologies in the jaws and skull base regions...
January 2017: Journal of Medical Imaging
https://www.readbyqxmd.com/read/28094650/new-education-models-must-not-take-us-back
#13
Janet Davies
Last year was a landmark one for nursing. As well as celebrating 100 years since the RCN was founded, in 2016 we learned of changes that will shape the future of our profession.
January 4, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28094482/real-time-ultrasound-guided-spinal-anesthesia-in-patients-with-predicted-difficult-anatomy
#14
Hesham Elsharkawy, Ankit Maheshwari, Rovnat Babazade, Anahi Perlas, Sherif Zaky, Loran M Soliman
BACKGROUND: There are limited reports of lumbar neuraxial blocks using real-time ultrasound in patients with predicted difficulties. We compared the number of attempts to perform spinal anesthesia using real time ultrasound guidance versus landmark technique in patients meeting predefined criteria for difficult spinal anesthesia. We also compared procedure time, block success, patient satisfaction and difficulty scores between groups. METHODS: Following institutional review board approval patients scheduled for total hip or knee arthroplasty with expected difficulty to perform spinal anesthesia were included...
January 17, 2017: Minerva Anestesiologica
https://www.readbyqxmd.com/read/28094265/haematological-cancer-landmark-survival-achieved-in-mm
#15
David Killock
No abstract text is available yet for this article.
January 17, 2017: Nature Reviews. Clinical Oncology
https://www.readbyqxmd.com/read/28093049/efficient-variational-approach-to-multimodal-registration-of%C3%A2-anatomical%C3%A2-and%C3%A2-functional-intra-patient-tumorous-brain-data
#16
Alvar-Ginés Legaz-Aparicio, Rafael Verdú-Monedero, Jorge Larrey-Ruiz, Juan Morales-Sánchez, Fernando López-Mir, Valery Naranjo, Ángela Bernabéu
This paper addresses the functional localization of intra-patient images of the brain. Functional images of the brain (fMRI and PET) provide information about brain function and metabolism whereas anatomical images (MRI and CT) supply the localization of structures with high spatial resolution. The goal is to find the geometric correspondence between functional and anatomical images in order to complement and fuse the information provided by each imaging modality. The proposed approach is based on a variational formulation of the image registration problem in the frequency domain...
November 29, 2016: International Journal of Neural Systems
https://www.readbyqxmd.com/read/28092723/pertuzumab-and-breast-cancer-another-piece-in-the-anti-her2-puzzle
#17
Dr Lorenzo Gerratana, Dr Marta Bonotto, Dr Claudia Bozza, Dr Elena Ongaro, Dr Valentina Fanotto, Dr Giacomo Pelizzari, Prof Fabio Puglisi
The mechanism of action of pertuzumab, a recombinant anti-HER2 humanized monoclonal antibody, is complementary to trastuzumab's. On June 8, 2012, the Food and Drug Administration approved the combination of pertuzumab with trastuzumab and docetaxel as first-line treatment of HER2-positive metastatic breast cancer. Furthermore, pertuzumab is the first drug to be approved in the neoadjuvant setting using a pathological complete response as an endpoint. Areas covered: The review provides insights into the main mechanisms of action of pertuzumab...
January 16, 2017: Expert Opinion on Biological Therapy
https://www.readbyqxmd.com/read/28092219/the-21st-century-cures-act-pharmacoeconomic-boon-or-bane
#18
Roger Lee Mendoza
Barriers to entry in healthcare markets constitute one of the overriding concerns of health economists. The recent enactment of the 21st Century Cures Act in the United States is one landmark legislation that reduces statutory entry barriers to the discovery, development, testing and licensing of drugs and medical devices. However, it brings with it many critical challenges concerning the safety, efficacy and value of drugs and devices, along with novel opportunities for medical innovation and faster treatment of diseases...
January 16, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/28089839/maxillary-artery-to-middle-cerebral-artery-bypass-a-novel-technique-for-exposure-of-the-maxillary-artery
#19
Kaan Yagmurlu, M Yashar S Kalani, Nikolay L Martirosyan, Sam Safavi-Abbasi, Evgenii Belykh, Avra S Laarakker, Peter Nakaji, Joseph M Zabramski, Mark C Preul, Robert F Spetzler
OBJECTIVES: Define the maxillary artery (MaxA) anatomy and present a novel technique for exposing and preparing this vessel as a bypass donor. METHODS: Cadaveric and radiological studies were used to define the MaxA anatomy and illustrate a novel method for harvesting and preparing it for extracranial-to-intracranial bypass. RESULTS: The MaxA runs parallel to the frontal branch of the superficial temporal artery (STA) and is located on average 24...
January 9, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28089495/assessment-of-the-isometry-of-the-anterolateral-ligament-in-a-3-dimensional-weight-bearing-computed-tomography-simulation
#20
Karl Wieser, Philipp Fürnstahl, Fabio Carrillo, Sandro F Fucentese, Lazaros Vlachopoulos
PURPOSE: To simulate the most isometric insertion points of the anterolateral ligament (ALL) in a weight-bearing 3-dimensional computed tomography (CT) model using previously published anatomic landmarks and to define radiographic landmarks, which make for an easier identification of the optimal insertion points. METHODS: The most isometric femoral insertion points were analyzed for 10 individuals, using data of weight-bearing CT scans in increasing knee flexion positions...
January 12, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
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