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https://www.readbyqxmd.com/read/28823143/stent-thrombosis-and-optimal-duration-of-dual-antiplatelet-therapy-after-coronary-stenting-in-contemporary-practice
#1
Min Soo Cho, Duk-Woo Park
The introduction of drug-eluting stents (DES) in the practice of percutaneous coronary intervention (PCI) has substantially reduced angiographic and clinical restenosis but is associated with an increasing propensity for very late stent thrombosis (ST). Among several clinical, lesion, or procedure-related predictors of ST, early discontinuation of dual antiplatelet therapy (DAPT) is the most important factor for DES-associated late thrombosis; therefore, the optimal duration of DAPT is a major issue to be critically considered in the current DES era...
August 22, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/28822820/utility-of-3d-reconstruction-of-2d-liver-computed-tomography-magnetic-resonance-images-as-a-surgical-planning-tool-for-residents-in-liver-resection-surgery
#2
Caitlin T Yeo, Andrew MacDonald, Tamas Ungi, Andras Lasso, Diederick Jalink, Boris Zevin, Gabor Fichtinger, Sulaiman Nanji
OBJECTIVE: A fundamental aspect of surgical planning in liver resections is the identification of key vessel tributaries to preserve healthy liver tissue while fully resecting the tumor(s). Current surgical planning relies primarily on the surgeon's ability to mentally reconstruct 2D computed tomography/magnetic resonance (CT/MR) images into 3D and plan resection margins. This creates significant cognitive load, especially for trainees, as it relies on image interpretation, anatomical and surgical knowledge, experience, and spatial sense...
August 16, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28822724/finding-the-ledge-sagittal-analysis-of-bony-landmarks-of-the-orbit
#3
Peter J J Gooris, Barbara S Muller, Leander Dubois, Jan E Bergsma, Gertjan Mensink, Maaike F E van den Ham, Alfred G Becking, Karlien Seubring
PURPOSE: This study determined the average distances and angles between anatomic landmarks within the orbit, with an emphasis on localization of the orbital process of the palatine bone. This information will help the surgeon with treatment planning and surgical procedures. PATIENTS AND METHODS: Four anatomic landmarks were identified retrospectively on computed tomograms of 100 adult Caucasian patients (50 men and 50 women): the top of the infraorbital margin superior to the infraorbital foramen (point A), the top of the orbital process of the palatine bone (point B), the anteriormost bony portion of the superior orbital fissure (point C), and the ventrolateral aspect of the bony entrance of the optic canal (point D)...
July 25, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28821987/morphological-anatomy-of-thoracolumbar-nerve-roots-and-dorsal-root-ganglia
#4
Lina Leng, Li Liu, Daowen Si
The aim of this study is to ascertain the anatomic parameters of the spinal roots and dorsal root ganglia and to demonstrate their clinical significance. Samples from 24 adult autopsy subjects were obtained from roots and dorsal root ganglia at levels L1 through L5. The anatomic parameters of epidural nerve roots: the distance between the epidural nerve roots and the proximal edge of the dorsal root ganglia and the average diameter of the nerve root gradually, increased from L1 to L5. The midline nerve root angle gradually decreased from L1 to L5...
August 18, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28820842/-upper-extremity-innervation-patterns-and-clinical-implications-for-nerve-and-tendon-transfer
#5
Ellen Y Lee, Sandeep J Sebastin, Andre Cheah, V P Kumar, Aymeric Y T Lim
BACKGROUND: We previously studied the intramuscular innervation of 150 upper limb muscles and demonstrated that certain patterns of intramuscular innervation allowed muscles to be split into compartments with independent function. This study aims to determine the location, extra-muscular course, and number of motor nerve branches of upper limb peripheral nerves. We want to combine this information with our previous work to create a blueprint of upper limb neuromuscular anatomy that would be useful in reconstructive surgery...
August 8, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28820608/skeletal-muscle-ultrasound-in-critical-care-a-tool-in-need-of-translation
#6
Marina Mourtzakis, Selina Parry, Bronwen Connolly, Zudin Puthucheary
With the emerging interest in documenting and understanding muscle atrophy and function in critically ill patients and survivors, ultrasonography has transformational potential in measuring muscle quantity and quality. Here, we discuss the importance of quantifying skeletal muscle in the ICU setting. We also identify the merits and limitations of various modalities that are capable of accurately and precisely measuring muscularity. Ultrasound is emerging as a potentially powerful tool for skeletal muscle quantification; however, there are key challenges that need to be addressed in future work to ensure useful interpretation and comparability of results across diverse observational and interventional studies...
August 18, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28818647/malocclusion-class-ii-division-1-skeletal-and-dental-relationships-measured-by-cone-beam-computed-tomography
#7
Yiling Xu, Heesoo Oh, Manuel O Lagravère
OBJECTIVES: The purpose of this study was to locate traditionally-used landmarks in two-dimensional (2D) images and newly-suggested ones in three-dimensional (3D) images (cone-beam computer tomographies [CBCTs]) and determine possible relationships between them to categorize patients with Class II-1 malocclusion. METHODS: CBCTs from 30 patients diagnosed with Class II-1 malocclusion were obtained from the University of Alberta Graduate Orthodontic Program database...
August 14, 2017: International Orthodontics
https://www.readbyqxmd.com/read/28817631/a-computational-model-for-biosonar-echoes-from-foliage
#8
Chen Ming, Anupam Kumar Gupta, Ruijin Lu, Hongxiao Zhu, Rolf Müller
Since many bat species thrive in densely vegetated habitats, echoes from foliage are likely to be of prime importance to the animals' sensory ecology, be it as clutter that masks prey echoes or as sources of information about the environment. To better understand the characteristics of foliage echoes, a new model for the process that generates these signals has been developed. This model takes leaf size and orientation into account by representing the leaves as circular disks of varying diameter. The two added leaf parameters are of potential importance to the sensory ecology of bats, e...
2017: PloS One
https://www.readbyqxmd.com/read/28817183/combined-high-intensity-local-treatment-and-systemic-therapy-in-metastatic-head-and-neck-squamous-cell-carcinoma-an-analysis-of-the-national-cancer-data-base
#9
Zachary S Zumsteg, Michael Luu, Emi J Yoshida, Sungjin Kim, Mourad Tighiouart, John M David, Stephen L Shiao, Alain C Mita, Kevin S Scher, Eric J Sherman, Nancy Y Lee, Allen S Ho
BACKGROUND: There is increasing evidence that primary tumor ablation can improve survival for some cancer patients with distant metastases. This may be particularly applicable to head and neck squamous cell carcinoma (HNSCC) because of its tropism for locoregional progression. METHODS: This study included patients with metastatic HNSCC undergoing systemic therapy identified in the National Cancer Data Base. High-intensity local treatment was defined as radiation doses ≥ 60 Gy or oncologic resection of the primary tumor...
August 17, 2017: Cancer
https://www.readbyqxmd.com/read/28817161/biomechanical-evaluation-of-unicortical-stress-risers-of-the-proximal-humerus-associated-with-pectoralis-major-repair
#10
David J Wilson, Brian P Milam, William F Scully, Todd P Balog, Kyong S Min, Christopher S Chen, Bryant G Marchant, Edward D Arrington
Proximal humerus fracture after pectoralis major tendon repair has been recently reported. Although this complication is rare, it may be possible to decrease such risk using newer techniques for myotenodesis. This study was designed to evaluate various unicortical stress risers created at the proximal humeral metadiaphysis during myotenodesis for repair of pectoralis major ruptures. A simulated pectoralis major myotenodesis was performed using fourth-generation Sawbones (N=30). Using previously described anatomic landmarks for the tendinous insertion, 3 repair techniques were compared: bone trough, tenodesis screws, and suture anchors (N=10 each)...
August 17, 2017: Orthopedics
https://www.readbyqxmd.com/read/28816478/towards-a-unified-model-of-vision-and-attention-effects-of-visual-landmarks-and-identity-cues-on-covert-and-overt-attention-movements
#11
Anthony J Lambert, Jaimie Wilkie, Andrea Greenwood, Nathan Ryckman, Evatte Sciberras-Lim, Laura-Jane Booker, Lenore Tahara-Eckl
To what extent are shifts of attention driven by encoding of visual-spatial landmarks, associated with useful locations, or by encoding of environmental cues that act as symbolic representations, providing information about where to look next? In Experiment 1 we found that when cues were presented with a long exposure time (300 ms) attention shifts were driven by the symbolic identity of cue stimuli, independently of their visual-spatial (landmark) features; but when cues were exposed very briefly, (66 ms), attention shifts were independent of symbolic information, and were driven instead by visual landmark features...
August 17, 2017: Journal of Experimental Psychology. Human Perception and Performance
https://www.readbyqxmd.com/read/28816151/quantification-of-pediatric-abdominal-organ-motion-with-a-4-dimensional-magnetic-resonance-imaging-method
#12
Jinsoo Uh, Matthew J Krasin, Yimei Li, Xingyu Li, Christopher Tinkle, John T Lucas, Thomas E Merchant, Chiaho Hua
PURPOSE: To characterize respiration-induced abdominal organ motion in children receiving radiation treatment with a 4-dimensional (4D) magnetic resonance imaging (MRI) method. METHODS AND MATERIALS: We analyzed free-breathing coronal 4D MRI datasets acquired from 35 patients (aged 1-20 years) with abdominal tumors. A deformable image registration of the 4D MRI datasets was performed to derive motion trajectories of selected anatomic landmarks, from which organ motions were quantified...
September 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28815932/polymer-based-hybrid-nanocomposites-a-progress-toward-enhancing-interfacial-interaction-and-tailoring-advanced-applications
#13
REVIEW
Chang-Sik Ha
Organic/inorganic hybrid nanocomposites, in particular polymer based hybrid nanocomposites, constitute emerging advanced materials since they combine unique properties from the inorganic and organic (i. e. polymeric) components. We investigated three different hybrid nanocomposites depending on dimensions of the dispersed phase in the nanometer range,; polymer-layered silicate (PLS) nanocomposites where polymers are mixed with layered silicates, polymer/graphene oxide hybrid nanocomposites, and polymer hybrid nanocomposites with reinforcing polymers with isodimensional phases of inorganic silicas using sol-gel reactions...
August 17, 2017: Chemical Record: An Official Publication of the Chemical Society of Japan ... [et Al.]
https://www.readbyqxmd.com/read/28815893/the-facial-morphology-in-down-syndrome-a-3d-comparison-of-patients-with-and-without-obstructive-sleep-apnea
#14
Yasas S N Jayaratne, Ibrahim Elsharkawi, Eric A Macklin, Lauren Voelz, Gil Weintraub, Dennis Rosen, Brian G Skotko
Obstructive sleep apnea (OSA) occurs at a high prevalence in patients with Down syndrome (DS). A polysomnogram, which is often cumbersome and challenging, remains the gold standard method of diagnosing OSA. OSA in patients with DS is often attributed to skeletal and soft-tissue structural alterations that are characteristic of the DS phenotype; as such, we hypothesized that assessing anthropometric facial measurements may be predictive of OSA in patients with DS. We used the 3dMDface sterophotography system to capture and create 3D facial images, and we subsequently identified facial landmarks using a single, experienced investigator and utilizing proprietary software to calculate inter-landmark distances and angles...
August 17, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28815565/generation-of-animal-form-by-the-chordin-tolloid-bmp-gradient-100%C3%A2-years-after-d-arcy-thompson
#15
Edward M De Robertis, Yuki Moriyama, Gabriele Colozza
The classic book "On Growth and Form" by naturalist D'Arcy Thompson was published 100 years ago. To celebrate this landmark, we present experiments in the Xenopus embryo that provide a framework for understanding how simple, quantitative transformations of a morphogen gradient might have affected evolution and morphological diversity of organisms. D'Arcy Thompson proposed that different morphologies might be generated by modifying physical parameters in an underlying system of Cartesian coordinates that pre-existed in Nature and arose during evolutionary history...
August 16, 2017: Development, Growth & Differentiation
https://www.readbyqxmd.com/read/28815078/surgical-anatomy-of-the-omental-bursa-and-the-stomach-based-on-a-minimally-invasive-approach-different-approaches-and-technical-steps-to-resection-and-lymphadenectomy
#16
Hylke J F Brenkman, Nicole I van der Wielen, Jelle P Ruurda, Maarten S van Leeuwen, Joris J G Scheepers, Donald L van der Peet, Richard van Hillegersberg, Ronald L A W Bleys, Miguel A Cuesta
BACKGROUND: It is imperative for surgeons to have a proper knowledge of the omental bursa in order to perform an adequate dissection during minimally invasive surgery (MIS) of the upper gastrointestinal (GI) tract. This study aimed to describe (1) the various approaches which can be used to enter the bursa and to perform a complete lymphadenectomy, (2) the boundaries and anatomical landmarks of the omental bursa as seen during MIS, and (3) whether a bursectomy should be performed for oncological reasons in upper GI cancer...
July 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28814430/the-2017-eular-standardised-procedures-for-ultrasound-imaging-in-rheumatology
#17
Ingrid Möller, Iustina Janta, Marina Backhaus, Sarah Ohrndorf, David A Bong, Carlo Martinoli, Emilio Filippucci, Luca Maria Sconfienza, Lene Terslev, Nemanja Damjanov, Hilde Berner Hammer, Iwona Sudol-Szopinska, Walter Grassi, Peter Balint, George A W Bruyn, Maria Antonietta D'Agostino, Diana Hollander, Heidi J Siddle, Gabriela Supp, Wolfgang A Schmidt, Annamaria Iagnocco, Juhani Koski, David Kane, Daniela Fodor, Alessandra Bruns, Peter Mandl, Gurjit S Kaeley, Mihaela Micu, Carmen Ho, Violeta Vlad, Mario Chávez-López, Georgios Filippou, Carmen Elena Cerón, Rodina Nestorova, Maritza Quintero, Richard Wakefield, Loreto Carmona, Esperanza Naredo
BACKGROUND: In 2001, the European League Against Rheumatism developed and disseminated the first guidelines for musculoskeletal (MS) ultrasound (US) in rheumatology. Fifteen years later, the dramatic expansion of new data on MSUS in the literature coupled with technological developments in US imaging has necessitated an update of these guidelines. OBJECTIVES: To update the existing MSUS guidelines in rheumatology as well as to extend their scope to other anatomic structures relevant for rheumatology...
August 16, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28811571/identification-of-a-gene-encoding-slow-skeletal-muscle-troponin-t-as-a-novel-marker-for-immortalization-of-retinal-pigment-epithelial-cells
#18
Takuya Kuroda, Satoshi Yasuda, Hiroyuki Nakashima, Nozomi Takada, Satoko Matsuyama, Shinji Kusakawa, Akihiro Umezawa, Akifumi Matsuyama, Shin Kawamata, Yoji Sato
Human pluripotent stem cells (hPSCs) are leading candidate raw materials for cell-based therapeutic products (CTPs). In the development of hPSC-derived CTPs, it is imperative to ensure that they do not form tumors after transplantation for safety reasons. Because cellular immortalization is a landmark of malignant transformation and a common feature of cancer cells, we aimed to develop an in vitro assay for detecting immortalized cells in CTPs. We employed retinal pigment epithelial (RPE) cells as a model of hPSC-derived products and identified a gene encoding slow skeletal muscle troponin T (TNNT1) as a novel marker of immortalized RPE cells by comprehensive microarray analysis...
August 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28811048/receipt-of-nephrology-care-and-clinical-outcomes-among-veterans-with-advanced-ckd
#19
Enrica Fung, Tara I Chang, Glenn M Chertow, I-Chun Thomas, Steven M Asch, Manjula Kurella Tamura
BACKGROUND: Clinical practice guidelines recommend referral to nephrology when estimated glomerular filtration rate (eGFR) decreases to <30mL/min/1.73m(2); however, evidence for benefits of nephrology care are mixed. STUDY DESIGN: Observational cohort using landmark analysis. SETTINGS & PARTICIPANTS: A national cohort of veterans with advanced chronic kidney disease, defined as an outpatient eGFR≤30mL/min/1.73m(2) for January 1, 2010, through December 31, 2010, and a prior eGFR<60mL/min/1...
August 12, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28810347/-history-of-world-neurosurgery
#20
X Wang
In 5000 BC, South American tribes digged the bones in the living head to seek ways to communicate with the gods, which was primitive trephination and may be the first neurosurgical behavior. In 2600 BC, Imhotep in ancient Egypt took the brain out of the head from the nose, for a better preserve of the mummy, which was a prototype of modern transsphenoidal surgery. And the development of anatomy in ancient Greek laid a solid foundation for neurosurgery. From 500 to 1500 AD, the rise of religion and the occurrence of war, prompted a large number of craniocerebral trauma, which contributed greatly to the early development of neurosurgery as a distinct specialty...
May 28, 2017: Zhonghua Yi Shi za Zhi, Chinese Journal of Medical History
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