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https://www.readbyqxmd.com/read/29141496/power-and-pacing-calculations-based-on-real-time-locating-data-from-a-cross-country-skiing-sprint-race
#1
Mikael Swarén, Anders Eriksson
Pacing strategies in cross-country skiing have been investigated in several studies. However, none of the previous studies have been verified by collected skiing data giving the skiing velocities along a measured track. These can be used to calculate the propulsive power output. Collected real-time positioning data from a cross-country sprint skiing race were used to estimate the propulsive power by applying a power balance model. Analyses were made for the time-trial and the final for one female and one male skier...
November 15, 2017: Sports Biomechanics
https://www.readbyqxmd.com/read/29133295/head-injury-mechanisms-in-fis-world-cup-alpine-and-freestyle-skiers-and-snowboarders
#2
Sophie Elspeth Steenstrup, Arnhild Bakken, Tone Bere, Declan Alexander Patton, Roald Bahr
INTRODUCTION: Head injuries represent a concern in skiing and snowboarding, with traumatic brain injuries being the most common cause of death. AIM: To describe the mechanisms of head and face injuries among World Cup alpine and freestyle skiers and snowboarders. METHODS: We performed a qualitative analysis of videos obtained of head and face injuries reported through the International Ski Federation Injury Surveillance System during 10 World Cup seasons (2006-2016)...
November 13, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/29121834/head-injuries-in-urban-environment-skiing-and-snowboarding-a-retrospective-study-on-injury-severity-and-injury-mechanisms
#3
A Stenroos, L Handolin
BACKGROUND AND AIM: During the last decade urban skiing and snowboarding has gained a lot of popularity. In urban skiing/snowboarding riders try to balance on handrails and jump off buildings. Previous studies in skiing and snowboarding accidents have mostly been conducted at hospitals located close to alpine terrain with big ski resort areas. The aim of this study is to evaluate the types and severity of traumatic brain injuries occurring in small, suburban hills and in urban environment, and to characterize injury patterns to find out the specific mechanisms of injuries behind...
November 1, 2017: Scandinavian Journal of Surgery: SJS
https://www.readbyqxmd.com/read/29118270/upregulation-of-pir-gene-expression-induced-by-human-papillomavirus-e6-and-e7-in-epithelial-oral-and-cervical-cells
#4
Diego Carrillo, Juan P Muñoz, Hernán Huerta, Gabriel Leal, Alejandro Corvalán, Oscar León, Gloria M Calaf, Ulises Urzúa, Enrique Boccardo, Julio C Tapia, Francisco Aguayo
The hallmark of high-risk human papillomavirus (HR-HPV)-related carcinogenesis is E6 and E7 oncogene overexpression. The aim of this work was to characterize epithelial oral and cervical cancer cells that express HR-HPV E6 and E7 oncoproteins. Transcriptomic assay using DNA microarrays revealed that PIR gene expression was detected in oral cells in an HR-HPV E6/E7-dependent manner. In addition, PIR was overexpressed in HPV-positive SiHa and Ca Ski cells, whereas it was undetectable in HPV-negative C33A cells...
November 2017: Open Biology
https://www.readbyqxmd.com/read/29118052/why-not-consider-a-sex-factor-within-the-iso-11088-ski-binding-setting-standard
#5
Gerhard Ruedl, Martin Burtscher
No abstract text is available yet for this article.
November 8, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/29117228/the-pacing-strategy-and-technique-of-male-cross-country-skiers-with-different-levels-of-performance-during-a-15-km-classical-race
#6
Boye Welde, Thomas L Stöggl, Gunnar E Mathisen, Matej Supej, Chiara Zoppirolli, Andreas K Winther, Barbara Pellegrini, Hans-Christer Holmberg
In this study the pacing strategy, cycle characteristics and choice of technique of elite male cross-country (XC) skiers during a three-lap, 15-km classical race with interval start were measured. During the Norwegian Championships in 2016, fast (n = 18, age: 26±4 yr; height: 182±4 cm; body mass: 78±3 kg (means±SD)) and slow skiers (n = 18, age: 22±2 yr; height: 183±5 cm; body mass: 78±6 kg) were video recorded on flat (0°), intermediate (3.5°) and uphill sections (7.1°) of the first and final laps...
2017: PloS One
https://www.readbyqxmd.com/read/29083413/preribosomes-escaping-from-the-nucleus-are-caught-during-translation-by-cytoplasmic-quality-control
#7
Anshuk Sarkar, Matthias Thoms, Clara Barrio-Garcia, Emma Thomson, Dirk Flemming, Roland Beckmann, Ed Hurt
Assembly of fully functional ribosomes is a prerequisite for failsafe translation. This explains why maturing preribosomal subunits have to pass through an array of quality-control checkpoints, including nuclear export, to ensure that only properly assembled ribosomes engage in translation. Despite these safeguards, we found that nuclear pre-60S particles unable to remove a transient structure composed of ITS2 pre-rRNA and associated assembly factors, termed the 'foot', escape to the cytoplasm, where they can join with mature 40S subunits to catalyze protein synthesis...
October 30, 2017: Nature Structural & Molecular Biology
https://www.readbyqxmd.com/read/29077294/-nasal-flaring-as-a-predictor-of-mortality-in-patients-with-severe-dyspnea
#8
Eva Sierra Quintana, Carmen María Martínez Caballero, Sara Abigail Batista Pardo, Salas Abella Barraca, María de la Vieja Soriano
OBJECTIVES: To describe the clinical and epidemiologic characteristics of patients with nontraumatic medical problems rescued by a Spanish mountain emergency response service (061 Aragon). MATERIAL AND METHODS: Retrospective observational analysis of records of mountain rescues completed between July 2010 and December 2016. RESULTS: A total of 164 patients with nontraumatic medical emergencies were rescued; 82.3% were males. Most patients were between the ages of 50 and 59 years...
October 2017: Emergencias
https://www.readbyqxmd.com/read/29072299/reversing-ski-smad4-mediated-suppression-is-essential-for-th17-cell-differentiation
#9
Song Zhang, Motoki Takaku, Liyun Zou, Ai-di Gu, Wei-Chun Chou, Ge Zhang, Bing Wu, Qing Kong, Seddon Y Thomas, Jonathan S Serody, Xian Chen, Xiaojiang Xu, Paul A Wade, Donald N Cook, Jenny P Y Ting, Yisong Y Wan
T helper 17 (TH17) cells are critically involved in host defence, inflammation, and autoimmunity. Transforming growth factor β (TGFβ) is instrumental in TH17 cell differentiation by cooperating with interleukin-6 (refs 6, 7). Yet, the mechanism by which TGFβ enables TH17 cell differentiation remains elusive. Here we reveal that TGFβ enables TH17 cell differentiation by reversing SKI-SMAD4-mediated suppression of the expression of the retinoic acid receptor (RAR)-related orphan receptor γt (RORγt). We found that, unlike wild-type T cells, SMAD4-deficient T cells differentiate into TH17 cells in the absence of TGFβ signalling in a RORγt-dependent manner...
November 2, 2017: Nature
https://www.readbyqxmd.com/read/29065077/optimizing-half-squat-postactivation-potential-load-in-squat-jump-training-for-eliciting-relative-maximal-power-in-ski-jumpers
#10
Artur Gołaś, Michal Wilk, Petr Stastny, Adam Maszczyk, Katarzyna Pajerska, Adam Zając
Gołaś, A, Wilk, M, Stastny, P, Maszczyk, A, Pajerska, K, and Zając, A. Optimizing half squat postactivation potential load in squat jump training for eliciting relative maximal power in ski jumpers. J Strength Cond Res 31(11): 3010-3017, 2017-Training load manipulation in a single workout session can increase or decrease training effectiveness in terms of athletes' strength or power gains. In ski jumping, the complex training that elicits maximal power gains may take advantage of the postactivation potentiation (PAP) mechanism...
November 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29061875/dimple-on-the-shoulder-after-a-ski-injury
#11
Morteza Khodaee, Armando Vidal, Greg Gutierrez
CLINICAL INTRODUCTION: A 74-year-old woman was brought to the ski clinic shortly after a fall on her left shoulder while skiing. She did not remember the exact fall mechanism. She felt a popping sensation in her left shoulder and was unable to move her left arm due to severe pain. Her medical and social histories were unremarkable. On physical examination, she had a deformity in her left shoulder (figure 1). Her neurovascular examination was intact.emermed;34/11/740/F1F1F1Figure 1Photograph of the left shoulder on arrival showing an anterior 'dimple'...
November 2017: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/29052827/primary-exploration-for-radial-nerve-palsy-associated-with-unstable-closed-humeral-shaft-fracture
#12
Soo Hong Han, In Tae Hong, Ho Jae Lee, Sang June Lee, Uk Kim, Dong Won Kim
BACKGROUND: The treatment of radial nerve palsy caused by closed humeral shaft fracture is a matter of debate. The purpose of this study is to evaluate the outcome of early surgical management of radial nerve palsy in patients with unstable closed humeral shaft fractures and to determine whether patients with this injury should be surgically explored. METHODS: Medical records of 15 consecutive patients who had undergone open reduction and internal fixation for unstable closed humeral shaft fractures were reviewed...
September 2017: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/29052286/high-risk-respiratory-patients-experiences-of-bronchoscopy-with-conscious-sedation-and-analgesia-a-qualitative-study
#13
Catherine Saxon, Paul Fulbrook, Kwun Fong, Chantal F Ski
AIM: To understand the experiences of high-risk respiratory patients undergoing bronchoscopy with conscious sedation. BACKGROUND: Due to possible complications, high-risk respiratory patients are usually given smaller, cautious doses of sedation and analgesia for bronchoscopy. Described as 'conscious sedation', this facilitates depression of the patient's consciousness without causing respiratory compromise. Previously, studies have investigated patient experience using quantitative methods...
October 20, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29035988/helmet-use-and-risk-taking-behavior-among-skiers-and-snowboarders
#14
Stuart E Willick, Graham Wagner, Don Ericson, George Josten, Masaru Teramoto, Jeremy Davis
OBJECTIVE: To characterize factors associated with helmet use and risk-taking behavior among recreational skiers and snowboarders. DESIGN: Observational study. SETTING: Large, western United States mountain resort. PARTICIPANTS: 1285 male and female recreational skiers and snowboarders were interviewed during a single winter ski season. INDEPENDENT VARIABLES: Helmet use, demographic, and sport-related characteristics...
October 10, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/29028945/sphingosine-kinase-1-expression-in-peritoneal-macrophages-is-required-for-colon-carcinogenesis
#15
Hideki Furuya, Paulette M Tamashiro, Yoshiko Shimizu, Kayoko Iino, Rafael Peres, Runpu Chen, Yijun Sun, Yusuf A Hannun, Lina M Obeid, Toshihiko Kawamori
Accumulating evidence suggests that the sphingosine kinase 1 (SphK1)/sphingosine 1-phosphate (S1P) pathway plays a pivotal role in colon carcinogenesis. Our previous studies indicate that the SphK1/S1P pathway mediates colon carcinogenesis at least by regulating COX-2 expression and prostaglandin E2 (PGE2) production. However, the mechanisms by which this pathway regulates colon carcinogenesis are still unclear. First, we show that SphK1 deficient mice significantly attenuated azoxymethane (AOM)-induced colon carcinogenesis as measured by colon tumor incidence, multiplicity, and volume...
September 23, 2017: Carcinogenesis
https://www.readbyqxmd.com/read/29028622/virtual-reality-balance-training-for-elderly-similar-skiing-games-elicit-different-challenges-in-balance-training
#16
Aijse W de Vries, Gert Faber, Ilse Jonkers, Jaap H Van Dieen, Sabine M P Verschueren
BACKGROUND: Virtual Reality (VR) balance training may have advantages over regular exercise training in older adults. However, results so far are conflicting potentially due to the lack of challenge imposed by the movements in those games. Therefore, the aim of this study was to assess to which extent two similar skiing games challenge balance, as reflected in center of mass (COM) movements relative to their Functional Limits of Stability (FLOS). METHODS: Thirty young and elderly participants performed two skiing games, one on the Wii Balance board (Wiiski), which uses a force plate, and one with the Kinect sensor (Kinski), which performs motion tracking...
October 5, 2017: Gait & Posture
https://www.readbyqxmd.com/read/29028445/return-to-sport-specific-performance-after-primary-anterior-cruciate-ligament-reconstruction-a-systematic-review
#17
Nicholas G Mohtadi, Denise S Chan
BACKGROUND: Physicians counseling athletes on the prognosis of sport-specific performance outcomes after anterior cruciate ligament reconstruction (ACLR) depend on the published literature. However, critical appraisal of the validity and biases in these studies is required to understand how ACLR affects an athlete's ability to return to sport, the athlete's sport-specific performance, and his or her ability to achieve preinjury levels of performance. PURPOSE: This review identifies the published prognostic studies evaluating sport-specific performance outcomes after ACLR...
October 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29025065/-sleeping-under-the-starry-sky-cysticercal-encephalitis
#18
Sudheer Tale, Bharath A Chhabria, Atit A Gawalkar, Hanuma N Banavath, Ashish Bhalla
No abstract text is available yet for this article.
August 4, 2017: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/29024041/strength-training-improves-double-poling-performance-after-prolonged-submaximal-exercise-in-cross-country-skiers
#19
S Øfsteng, Ø Sandbakk, M van Beekvelt, D Hammarström, R Kristoffersen, J Hansen, G Paulsen, B R Rønnestad
The purpose of this study was to investigate the effects of adding strength training with or without vibration to cross-country (XC) skiers' endurance training on double poling (DP) performance, physiological and kinematic adaptations. Twenty-one well-trained male XC skiers combined endurance- and upper-body strength-training three times per week, either with (n=11) or without (n=10) superimposed vibrations for 8 weeks, whereas eight skiers performed endurance training only (CON). Testing included 1RM in upper-body exercises, work economy, neural activation, oxygen saturation in muscle and DP kinematics during a prolonged submaximal DP roller ski test which was directly followed by a time to exhaustion (TTE) test...
October 10, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28986832/assays-to-assess-arenaviral-glycoprotein-function
#20
Junjie Shao, Xiaoying Liu, Yuying Liang, Hinh Ly
Arenaviruses, such as Lassa virus (LASV) and Pichindé virus (PICV), are enveloped viruses with a bi-segmented ambisense RNA genome. The large (L) genomic segment encodes the Z matrix protein and the L RNA-dependent RNA polymerase, whereas the small (S) genomic segment encodes the nucleoprotein (NP) and the glycoprotein precursor complex (GPC). GPC is processed by signal peptidase in the endoplasmic reticulum into the stable signal peptide (SSP) and GP1/GP2, which is further cleaved by the Golgi-resident subtilisin kexin isozyme-1 (SKI-1)/site-1 protease (S1P) into the cellular receptor-recognition subunit GP1 and the transmembrane subunit GP2, which helps promote the membrane fusion reaction to allow virus entry into the cell...
2018: Methods in Molecular Biology
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