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Local field potentials

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https://www.readbyqxmd.com/read/28934654/a-case-study-of-air-quality-pesticides-and-odorous-phytochemicals-on-kauai-hawaii-usa
#1
Jun Wang, Robert Boesch, Qing X Li
This study was conducted after a series of incidences occurred at Waimea Canyon Middle School on Kauai, Hawaii. Some students and staff members exhibited symptoms such as throat irritation, tearing, and dizziness. These symptoms could be associated with natural causes or human activities, which include exposures to pesticides and odorous phytochemicals. At the time of the occurrences, Cleome gynandra (known locally as stinkweed) was growing in the fields near the school and might be a potential cause of the reported symptoms...
September 14, 2017: Chemosphere
https://www.readbyqxmd.com/read/28932809/aberrant-cortical-activity-in-multiple-gcamp6-expressing-transgenic-mouse-lines
#2
Nicholas A Steinmetz, Christina Buetfering, Jerome Lecoq, Christian R Lee, Andrew J Peters, Elina A K Jacobs, Philip Coen, Douglas R Ollerenshaw, Matthew T Valley, Saskia E J de Vries, Marina Garrett, Jun Zhuang, Peter A Groblewski, Sahar Manavi, Jesse Miles, Casey White, Eric Lee, Fiona Griffin, Joshua D Larkin, Kate Roll, Sissy Cross, Thuyanh V Nguyen, Rachael Larsen, Julie Pendergraft, Tanya Daigle, Bosiljka Tasic, Carol L Thompson, Jack Waters, Shawn Olsen, David J Margolis, Hongkui Zeng, Michael Hausser, Matteo Carandini, Kenneth D Harris
Transgenic mouse lines are invaluable tools for neuroscience but, as with any technique, care must be taken to ensure that the tool itself does not unduly affect the system under study. Here we report aberrant electrical activity, similar to interictal spikes, and accompanying fluorescence events in some genotypes of transgenic mice expressing GCaMP6 genetically encoded calcium sensors. These epileptiform events have been observed particularly, but not exclusively, in mice with Emx1-Cre and Ai93 transgenes, of either sex, across multiple laboratories...
September 2017: ENeuro
https://www.readbyqxmd.com/read/28931610/the-coupling-of-synaptic-inputs-to-local-cortical-activity-differs-among-neurons-and-adapts-following-stimulus-onset
#3
Nathaniel Caleb Wright, Mahmood Sayed Hoseini, Tansel Baran Yasar, Ralf Wessel
Cortical activity contributes significantly to the high variability of sensory responses of interconnected pyramidal neurons, which has crucial implications for sensory coding. Yet, largely because of technical limitations of in vivo intracellular recordings, the coupling of a pyramidal neuron's synaptic inputs to the local cortical activity has evaded full understanding. Here, we obtained excitatory synaptic conductance (g) measurements from putative pyramidal neurons and local field potential (LFP) recordings from adjacent cortical circuits during visual processing in the turtle whole-brain ex vivo preparation...
September 20, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28929474/-new-thalamic-potential-associated-with-somatosensory-evoked-potentials
#4
L Vega-Zelaya, C V Torres, M Navas-Garcia, R G Sola, J Pastor
INTRODUCTION: The response of the thalamus during the study with somatosensory evoked potentials (SSEP) is not sufficiently understood. CASE REPORT: A 17-year-old man undergoing surgery for deep brain stimulation in the centromedian nucleus for drug-resistant epilepsy under complete sedation. During the intervention, the responses to SSEPs of the thalamic nuclei were recorded by means of four microelectrodes. These responses can be decomposed into three types: local field potentials (LFP), low amplitude fast oscillations (LFO), and high amplitude slow oscillations (HSO)...
October 1, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/28929310/postoperative-radiotherapy-for-prostate-cancer-morbidity-of-local-only-or-local-plus-pelvic-radiotherapy
#5
Cora Waldstein, Wolfgang Dörr, Richard Pötter, Joachim Widder, Gregor Goldner
PURPOSE: The aim of this work was to characterise actuarial incidence and prevalence of early and late side effects of local versus pelvic three-dimensional conformal postoperative radiotherapy for prostate cancer. MATERIALS AND METHODS: Based on a risk-adapted protocol, 575 patients received either local (n = 447) or local-plus-pelvic (n = 128) radiotherapy. Gastrointestinal (GI) and genitourinary (GU) side effects (≥grade 2 RTOG/EORTC criteria) were prospectively assessed...
September 19, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28927833/modulation-of-hippocampal-activity-with-fornix-deep-brain-stimulation
#6
Paul H Stypulkowski, Scott R Stanslaski, Jonathon E Giftakis
BACKGROUND: Deep Brain Stimulation (DBS) within the Papez circuit is under investigation as a treatment for epilepsy and Alzheimer's disease. We previously reported the effects of stimulation at nodes within this network (anterior thalamic nucleus and hippocampus) on hippocampal activity in a large animal model, using a chronic implantable, clinical-grade system that permits concurrent stimulation and recording. OBJECTIVE: In this study we extended earlier work to compare the effects of fornix DBS on evoked potentials (EPs) and local field potential (LFP) activity within the hippocampus, and to assess closed-loop stimulation...
September 6, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28926184/experience-dependent-neural-plasticity-learning-and-memory-in-the-era-of%C3%A2-epitranscriptomics
#7
REVIEW
Laura J Leighton, Ke Ke, Esmi L Zajaczkowski, Jordan Edmunds, Robert C Spitale, Timothy W Bredy
In this short review, we highlight recent findings in the emerging field of epitranscriptomic mechanisms and discuss their potential role in neural plasticity, learning and memory. These include the influence of RNA modifications on activity-induced RNA structure states, RNA editing and RNA localization, and how qualitative state changes in RNA increase the functional diversity and information-carrying capacity of RNA molecules. We predict that RNA modifications may be just as important for synaptic plasticity and memory as quantitative changes in transcript and protein abundance, but with the added advantage of not being required to signal back to the nucleus, and therefore better suited to be coordinated with the temporal dynamics of learning...
September 19, 2017: Genes, Brain, and Behavior
https://www.readbyqxmd.com/read/28925905/nanomedicine-in-the-diagnosis-and-treatment-of-atherosclerosis-a-systematic-review
#8
Kannan Vaidyanathan, Sandhya Gopalakrishnan
BACKGROUND: Atherosclerosis is a chronic inflammatory condition causing very high morbidity and mortality. It is characterized by accumulation of plaques within arteries. Nanomedicine is an emerging field of medicine utilizing nanotechnology for advanced imaging and therapy. Nanomedicine has led to significant developments in the field of cardiovascular diseases, including atherosclerosis. Many nanoformulations have been developed with anti-atherosclerotic effects. Nanomedicine tools have been used in the imaging of atherosclerosis...
September 18, 2017: Cardiovascular & Hematological Disorders Drug Targets
https://www.readbyqxmd.com/read/28924008/primary-generators-of-visually-evoked-field-potentials-recorded-in-the-macaque-auditory-cortex
#9
Yoshinao Kajikawa, John F Smiley, Charles E Schroeder
Prior studies have reported "local" field potential (LFP) responses to faces in the macaque auditory cortex and have suggested that such face-LFPs may be substrates of audiovisual integration. However, while field potentials (FPs) may reflect the synaptic currents of neurons near the recording electrode, due to the use of a distant reference electrode, they often reflect those of synaptic activity occurring in distant sites as well. Thus, FP recordings within a given brain region (e.g., auditory cortex) may be "contaminated" by activity generated elsewhere in the brain...
September 18, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28923132/characterization-of-environmental-pseudomonas-aeruginosa-using-multilocus-sequence-typing-scheme
#10
Júlia Radó, Edit Kaszab, Tünde Petrovics, Judit Pászti, Balázs Kriszt, Sándor Szoboszlay
PURPOSE: The objectives of this study were to examine environmental (hydrocarbon degrading) Pseudomonas aeruginosa isolates with Multilocus Sequence Typing (MLST) and to determine their relevant features, such as serotype, virulence genes, biofilm forming ability and hydrocarbon degrading capacity. METHODOLOGY: The diversity of environmental isolates was assessed with an MLST scheme. Investigation of virulence determinants included serotyping, hemolytic activity test and the detection of virulence genes exoS, exoY, exoT, exoU, exoA...
September 19, 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28922856/building-up-absence-seizures-in-the-somatosensory-cortex-from-network-to-cellular-epileptogenic-processes
#11
Guillaume Jarre, Tristan Altwegg-Boussac, Mark S Williams, Florian Studer, Mathilde Chipaux, Olivier David, Stéphane Charpier, Antoine Depaulis, Séverine Mahon, Isabelle Guillemain
The epileptogenic processes leading to recurrent seizures in Genetic Epilepsies are largely unknown. Using the Genetic Absence Epilepsy Rat from Strasbourg, we investigated in vivo the network and single neuron mechanisms responsible for the early emergence of epileptic activity. Local field potential recordings in the primary somatosensory cortex (SoCx), from the second post-natal week to adulthood, showed that immature cortical discharges progressively evolved into typical spike-and-wave discharges following a 3-step maturation process...
September 1, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28922374/fractional-laser-exposure-induces-neutrophil-infiltration-n1-phenotype-into-the-tumor-and-stimulates-systemic-anti-tumor-immune-response
#12
Masayoshi Kawakubo, Shadmehr Demehri, Dieter Manstein
BACKGROUND: Ablative fractional photothermolysis (aFP) using a CO2 laser generates multiple small diameter tissue lesions within the irradiation field. aFP is commonly used for a wide variety of dermatological indications, including treatment of photodamaged skin and dyschromia, drug delivery and modification of scars due to acne, surgical procedures and burns. In this study we explore the utility of aFP for treating oncological indications, including induction of local tumor regression and inducing anti-tumor immunity, which is in marked contrast to current indications of aFP...
2017: PloS One
https://www.readbyqxmd.com/read/28922278/defining-the-critical-elements-for-the-most-common-procedures-in-spine-surgery-a-consensus-of-orthopaedic-and-neurosurgical-surgeons
#13
Joseph L Laratta, Samuel Cohen-Tanugi, Jamal N Shillingford, Joseph M Lombardi, Lawrence G Lenke, K Daniel Riew, Ronald A Lehman, Steven C Ludwig
STUDY DESIGN: Survey. OBJECTIVE: To define the critical elements of common spine surgeries. SUMMARY OF BACKGROUND DATA: Despite significant relevance to the field of spine surgery, the term "critical element" of surgery has not been clearly defined. Every surgical procedure involves numerous steps, each with its own potential for complications and harm to the patient. Despite its crucial role in surgical training, billing, and the ethicality of concurrent surgery, the term "critical element" of surgery has not been defined...
September 15, 2017: Spine
https://www.readbyqxmd.com/read/28922117/magnetic-resonance-mediated-radiofrequency-ablation
#14
Yik-Kiong Hue, Alexander R Guimaraes, Ouri Cohen, Erez Nevo, Abraham Roth, Jerome L Ackerman, Jerome L Ackerman
OBJECTIVE: To introduce magnetic resonance mediated radiofrequency ablation (MR-RFA), in which the MRI scanner uniquely serves both diagnostic and therapeutic roles. In MR-RFA scanner-induced RF heating is channeled to the ablation site via a Larmor frequency RF pickup device and needle system, and controlled via the pulse sequence. METHODS: MR-RFA was evaluated with simulation of electric and magnetic fields to predict the increase in local specific-absorption-rate (SAR)...
September 18, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28920964/directed-emission-of-cdse-nanoplatelets-originating-from-strongly-anisotropic-2d-electronic-structure
#15
Riccardo Scott, Jan Heckmann, Anatol V Prudnikau, Artsiom Antanovich, Aleksandr Mikhailov, Nina Owschimikow, Mikhail Artemyev, Juan I Climente, Ulrike Woggon, Nicolai B Grosse, Alexander W Achtstein
Intrinsically directional light emitters are potentially important for applications in photonics including lasing and energy-efficient display technology. Here, we propose a new route to overcome intrinsic efficiency limitations in light-emitting devices by studying a CdSe nanoplatelets monolayer that exhibits strongly anisotropic, directed photoluminescence. Analysis of the two-dimensional k-space distribution reveals the underlying internal transition dipole distribution. The observed directed emission is related to the anisotropy of the electronic Bloch states governing the exciton transition dipole moment and forming a bright plane...
September 18, 2017: Nature Nanotechnology
https://www.readbyqxmd.com/read/28920903/brain-control-of-an-external-device-by-extracting-the-highest-force-related-contents-of-local-field-potentials-in-freely-moving-rats
#16
Abed Khorasani, Reza Foodeh, Vahid Shalchyan, Mohammad Reza Daliri
A local field potential (LFP) signal is an alternative source to neural action potentials for decoding kinematic and kinetic information from the brain. Here we demonstrate that better extraction of force-related features from multichannel LFPs improves the accuracy of force decoding. We propose that applying canonical correlation analysis (CCA) filter on the envelopes of separate frequency bands (band-specific CCA) seperates non- task related information from the LFPs. The decoding accuracy of the continuous force signal based on the proposed method were compared with three feature reduction methods: 1) Band-specific principal component analysis (bandspecific PCA) method that extract the components which leads to maximum variance from envelopes of different frequency bands, 2) Correlation coefficient-based (CC-based) feature reduction that selects the best features from the envelopes sorted based on the absolute correlation coefficient between each envelope and the target force signal and 3) Mutual information -based (MI-based) feature reduction that selects the best features from the envelopes sorted based on the mutual information between each envelope and output force signal...
September 12, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28920434/ultralow-temperature-solution-processed-aluminum-oxide-dielectrics-via-local-structure-control-of-nanoclusters
#17
Jeong-Wan Jo, Yong-Hoon Kim, Joohyung Park, Jae Sang Heo, Seongpil Hwang, Won-June Lee, Myung-Han Yoon, Myung-Gil Kim, Sung Kyu Park
Oxide dielectric materials play a key role in a wide range of high-performance solid-state electronics from semiconductor devices to emerging wearable and soft bio-electronic devices. Although lots of previous advances are noteworthy, their typical processing temperature still far exceeds the thermal limitations of soft materials, impeding their wide utilization in these emerging fields. Here, we report an innovative route to form highly reliable aluminum-oxide dielectric films using an ultralow temperature (< 60 ˚C) solution process with a class of oxide nanocluster precursors...
September 18, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28919029/recent-advances-of-controlled-drug-delivery-using-microfluidic-platforms
#18
REVIEW
Sharma T Sanjay, Wan Zhou, Maowei Dou, Hamed Tavakoli, Lei Ma, Feng Xu, XiuJun Li
Conventional systematically-administered drugs distribute evenly throughout the body, get degraded and excreted rapidly while crossing many biological barriers, leaving minimum amounts of the drugs at pathological sites. Controlled drug delivery aims to deliver drugs to the target sites at desired rates and time, thus enhancing the drug efficacy, pharmacokinetics, and bioavailability while maintaining minimal side effects. Due to a number of unique advantages of the recent microfluidic lab-on-a-chip technology, microfluidic lab-on-a-chip has provided unprecedented opportunities for controlled drug delivery...
September 15, 2017: Advanced Drug Delivery Reviews
https://www.readbyqxmd.com/read/28918300/dynamical-properties-of-lfps-from-mice-with-unilateral-injection-of-tent
#19
Eleonora Vannini, Matteo Caleo, Santi Chillemi, Angelo Di Garbo
Local field potential (LFP) recordings were performed from the visual cortex (V1) of a focal epilepsy mouse model. Epilepsy was induced by a unilateral injection of the synaptic blocker tetanus neurotoxin (TeNT). LFP signals were simultaneously recorded from V1 of both hemispheres of each animal under acute and chronic conditions (i.e. during and after the period of TeNT action). All data were analysed by using nonlinear time series methods. Suitable values of the lag time and embedding dimension for phase space reconstruction were estimated by employing well-known methods...
September 13, 2017: Bio Systems
https://www.readbyqxmd.com/read/28917974/cross-cultural-analysis-of-medicinal-plants-commonly-used-in-ethnoveterinary-practices-at-south-waziristan-agency-and-bajaur-agency-federally-administrated-tribal-areas-fata-pakistan
#20
Muhammad Abdul Aziz, Muhammad Adnan, Amir Hasan Khan, Muhammad Sufyan, Shahid Niaz Khan
ETHNOPHARMACOLOGICAL RELEVANCE: In remote areas, medicinal plants have an imperative role in curing various livestock's ailments. In Pakistan, people residing in remote areas including South Waziristan Agency and Bajaur Agency depend on traditional herbal remedies for treating their domestic animals. Medicinal plants are an important part of the medical system in these Agencies. The prime goal of the current study is to explore the ethnoveterinary practices in the two regions and discuss cross-cultural consensus on the use of medicinal plants...
September 14, 2017: Journal of Ethnopharmacology
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