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Local field potentials

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https://www.readbyqxmd.com/read/28327449/integrated-local-binary-pattern-texture-features-for-classification-of-breast-tissue-imaged-by-optical-coherence-microscopy
#1
Sunhua Wan, Hsiang-Chieh Lee, Xiaolei Huang, Ting Xu, Tao Xu, Xianxu Zeng, Zhan Zhang, Yuri Sheikine, James L Connolly, James G Fujimoto, Chao Zhou
This paper proposes a texture analysis technique that can effectively classify different types of human breast tissue imaged by Optical Coherence Microscopy (OCM). OCM is an emerging imaging modality for rapid tissue screening and has the potential to provide high resolution microscopic images that approach those of histology. OCM images, acquired without tissue staining, however, pose unique challenges to image analysis and pattern classification. We examined multiple types of texture features and found Local Binary Pattern (LBP) features to perform better in classifying tissues imaged by OCM...
March 8, 2017: Medical Image Analysis
https://www.readbyqxmd.com/read/28325490/development-and-application-of-a-new-in-line-coupling-of-a-miniaturized-boronate-affinity-monolithic-column-with-capillary-zone-electrophoresis-for-the-selective-enrichment-and-analysis-of-cis-diol-containing-compounds
#2
Maria Betzabeth Espina-Benitez, Jérôme Randon, Claire Demesmay, Vincent Dugas
An integrated, miniaturized and fully automated system was developed for the analysis (preconcentration/purification, separation and detection) of cis-diol containing molecules in complex matrices. This innovative in-line coupling system was achieved via the in-situ and localized synthesis of a short segment of silica-based monolith at the inlet of a 75-μm inner diameter fused silica capillary. The monolithic segment was locally functionalized with an acrylamide derivative of phenylboronic acid by free radical photopolymerization within 10min of irradiation time...
March 9, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28324983/the-precuneus-may-encode-irrationality-in-human-gambling
#3
P Sacre, M S D Kerr, S Subramanian, K Kahn, J Gonzalez-Martinez, M A Johnson, S V Sarma, J T Gale
Humans often make irrational decisions, especially psychiatric patients who have dysfunctional cognitive and emotional circuitry. Understanding the neural basis of decision-making is therefore essential towards patient management, yet current studies suffer from several limitations. Functional magnetic resonance imaging (fMRI) studies in humans have dominated decision-making neuroscience, but have poor temporal resolution and the blood oxygenation level-dependent signal is only a proxy for neural activity. On the other hand, lesion studies in humans used to infer functionality in decision-making lack characterization of neural activity altogether...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324965/high-dielectric-material-in-mri-numerical-assessment-of-the-reduction-of-the-induced-local-power-on-implanted-cardiac-leads
#4
Eugenio Mattei, Elena Lucano, Federica Censi, Leonardo M Angelone, Giovanni Calcagnini
High dielectric materials (HDM) have been proposed in magnetic resonance imaging (MRI) to increase the signal-to-noise ratio (SNR) of the images acquired while reducing the radiofrequency (RF) absorption in tissue. The aim of this study is to assess the potential merit of using HDM to reduce power induced at the tip of an endocardial lead in patients undergoing MRI. Numerical simulations were performed using a commercial finite-differences time-domain (FDTD) software to model the RF field generated by a birdcage body coil at 64 MHz on a human body model...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324940/use-of-local-field-potentials-of-dissociated-cultures-grown-on-multi-electrode-arrays-for-pharmacological-assays
#5
G D C Mendis, E Morrisroe, C A Reid, S K Halgamuge, S Petrou
In vitro Multi-Electrode Arrays (MEA) are an extracellular recording technology that enables the analysis of networks of neurons in vitro. Neurons in culture exhibit a range of behavioral dynamics, which can be measured in terms of individual action potentials, network-wide synchronized firing and a host of other features that characterize network activity. MEA data analysis was historically focused on high frequency spike data forgoing the low frequency content of the signal. In this study, we use local field potentials, which are low frequency components of MEA signals, to differentiate between two types of antiepileptic drugs (p<;0...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324930/rtms-enhanced-gamma-oscillation-through-strengthened-network-connection
#6
Mengmeng Dou, Xin Tian
Gamma oscillations emerge generally in working memory to aspect of higher cognitive functions, and typically with the interaction of brain network. How is gamma oscillatory activity influenced by the functional connection in the brain'a network? How can gamma oscillations be increased by neural modulation to result in potential benefits for working memory? The present study aims to investigate the intensity of gamma oscillations modulated by low frequency repetitive transcranial magnetic stimulation (rTMS), and the possible brain network mechanism of increased gamma oscillations during working memory task in rats...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28323430/dual-scattering-near-field-microscope-for-correlative-nanoimaging-of-sers-and-electromagnetic-hotspots
#7
Patryk Kusch, Stefan Mastel, Niclas Sven Mueller, Nieves Morquillas, Sebastian Heeg, Roman Gorbachev, Fredrik Schedin, Uwe Huebner, Jose Ignacio Pascual, Stephanie Reich, Rainer Hillenbrand
Surface-enhanced Raman spectroscopy (SERS) enables sensitive chemical studies and materials identification, relying on electromagnetic (EM) and chemical-enhancement mechanisms. Here we introduce a tool for the correlative nanoimaging of EM and SERS hotspots - areas of strongly enhanced EM fields and Raman scattering, respectively. To that end, we implemented a grating spectrometer into a scattering-type scanning near-field optical microscope (s-SNOM) for mapping of both the elastically and inelastically (Raman) scattered light from the near-field probe - a sharp silicon tip...
March 21, 2017: Nano Letters
https://www.readbyqxmd.com/read/28319710/glacial-lake-inventory-and-lake-outburst-potential-in-uzbekistan
#8
Maxim A Petrov, Timur Y Sabitov, Irina G Tomashevskaya, Gleb E Glazirin, Sergey S Chernomorets, Elena A Savernyuk, Olga V Tutubalina, Dmitriy A Petrakov, Leonid S Sokolov, Mikhail D Dokukin, Giorgos Mountrakis, Virginia Ruiz-Villanueva, Markus Stoffel
Climate change has been shown to increase the number of mountain lakes across various mountain ranges in the World. In Central Asia, and in particular on the territory of Uzbekistan, a detailed assessment of glacier lakes and their evolution over time is, however lacking. For this reason we created the first detailed inventory of mountain lakes of Uzbekistan based on recent (2002-2014) satellite observations using WorldView-2, SPOT5, and IKONOS imagery with a spatial resolution from 2 to 10m. This record was complemented with data from field studies of the last 50years...
March 16, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28319611/functional-electronic-inversion-layers-at-ferroelectric-domain-walls
#9
J A Mundy, J Schaab, Y Kumagai, A Cano, M Stengel, I P Krug, D M Gottlob, H Dog Anay, M E Holtz, R Held, Z Yan, E Bourret, C M Schneider, D G Schlom, D A Muller, R Ramesh, N A Spaldin, D Meier
Ferroelectric domain walls hold great promise as functional two-dimensional materials because of their unusual electronic properties. Particularly intriguing are the so-called charged walls where a polarity mismatch causes local, diverging electrostatic potentials requiring charge compensation and hence a change in the electronic structure. These walls can exhibit significantly enhanced conductivity and serve as a circuit path. The development of all-domain-wall devices, however, also requires walls with controllable output to emulate electronic nano-components such as diodes and transistors...
March 20, 2017: Nature Materials
https://www.readbyqxmd.com/read/28317467/ethnographic-perspectives-on-global-mental-health
#10
Sumeet Jain, David M R Orr
The field of Global Mental Health (GMH) aims to influence mental health policy and practice worldwide, with a focus on human rights and access to care. There have been important achievements, but GMH has also been the focus of scholarly controversies arising from political, cultural, and pragmatic critiques. These debates have become increasingly polarized, giving rise to a need for more dialogue and experience-near research to inform theorizing. Ethnography has much to offer in this respect. This paper frames and introduces five articles in this issue of Transcultural Psychiatry that illustrate the role of ethnographic methods in understanding the effects and implications of the field of global mental health on mental health policy and practice...
December 2016: Transcultural Psychiatry
https://www.readbyqxmd.com/read/28316893/contrasting-determinants-for-the-introduction-and-establishment-success-of-exotic-birds-in-taiwan-using-decision-trees-models
#11
Shih-Hsiung Liang, Bruno Andreas Walther, Bao-Sen Shieh
BACKGROUND: Biological invasions have become a major threat to biodiversity, and identifying determinants underlying success at different stages of the invasion process is essential for both prevention management and testing ecological theories. To investigate variables associated with different stages of the invasion process in a local region such as Taiwan, potential problems using traditional parametric analyses include too many variables of different data types (nominal, ordinal, and interval) and a relatively small data set with too many missing values...
2017: PeerJ
https://www.readbyqxmd.com/read/28315444/directional-spread-of-activity-in-synaptic-networks-of-the-human-lateral-amygdala
#12
Stéphanie Graebenitz, Manuela Cerina, Jörg Lesting, Olga Kedo, Ali Gorji, Heinz Pannek, Volkmar Hans, Karl Zilles, Hans-Christian Pape, Erwin-Josef Speckmann
Spontaneous epileptiform activity has previously been observed in lateral amygdala (LA) slices derived from patients with intractable-temporal lobe epilepsy. The present study aimed to characterize intranuclear LA synaptic connectivity and to test the hypothesis that differences in the spread of flow of neuronal activity may relate to spontaneous epileptiform activity occurrence. Electrical activity was evoked through electrical microstimulation in acute human brain slices containing the LA, signals were recorded as local field potentials combined with fast optical imaging of voltage-sensitive dye fluorescence...
March 14, 2017: Neuroscience
https://www.readbyqxmd.com/read/28314368/metallic-nanoparticles-reduce-the-migration-of-human-fibroblasts-in-vitro
#13
Larissa Fernanda de Araújo Vieira, Marvin Paulo Lins, Iana Mayane Mendes Nicácio Viana, Jeniffer Estevão Dos Santos, Salete Smaniotto, Maria Danielma Dos Santos Reis
Nanoparticles have extremely wide applications in the medical and biological fields. They are being used in biosensors, local drug delivery, diagnostics, and medical therapy. However, the potential effects of nanoparticles on target cell and tissue function, apart from cytotoxicity, are not completely understood. Thus, the aim of this study was to investigate the in vitro effects of silver nanoparticles (AgNPs) and gold nanoparticles (AuNPs) on human fibroblasts with respect to their interaction with the extracellular matrix and in cell migration...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28314154/streamlined-approach-to-mapping-the-magnetic-induction-of-skyrmionic-materials
#14
Jordan J Chess, Sergio A Montoya, Tyler R Harvey, Colin Ophus, Simon Couture, Vitaliy Lomakin, Eric E Fullerton, Benjamin J McMorran
Recently, Lorentz transmission electron microscopy (LTEM) has helped researchers advance the emerging field of magnetic skyrmions. These magnetic quasi-particles, composed of topologically non-trivial magnetization textures, have a large potential for application as information carriers in low-power memory and logic devices. LTEM is one of a very few techniques for direct, real-space imaging of magnetic features at the nanoscale. For Fresnel-contrast LTEM, the transport of intensity equation (TIE) is the tool of choice for quantitative reconstruction of the local magnetic induction through the sample thickness...
February 28, 2017: Ultramicroscopy
https://www.readbyqxmd.com/read/28306259/building-a-more-predictive-protein-force-field-a-systematic-and-reproducible-route-to-amber-fb15
#15
Lee-Ping Wang, Keri A McKiernan, Joseph Gomes, Kyle A Beauchamp, Teresa Head-Gordon, Julia E Rice, William C Swope, Todd J Martínez, Vijay S Pande
The increasing availability of high-quality experimental data and first-principles calculations creates opportunities for developing more accurate empirical force fields for simulation of proteins. We developed the AMBER-FB15 protein force field by building a high-quality quantum chemical data set consisting of comprehensive potential energy scans and employing the ForceBalance software package for parameter optimization. The optimized potential surface allows for more significant thermodynamic fluctuations away from local minima...
March 17, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28299887/fibroepithelial-lesions-in-the-breast-of-adolescent-females-a-clinicopathological-study-of-54-cases
#16
Dara S Ross, Dilip D Giri, Muzaffar M Akram, Jeffrey P Catalano, Cristina Olcese, Kimberly J Van Zee, Edi Brogi
Fibroepithelial lesions (FELs) are the most frequent breast tumors in adolescent females. The pubertal hormonal surge could impact the growth and microscopic appearance of FELs in this age group. In this study, we evaluate the morphology and clinical behavior of FELs in adolescents. We searched the 1992-2012 pathology data base for FELs in females 18 years old or younger (F ≤18 years). Seven FELs from 1975 to 1983 were also included. Three pathologists reviewed all available material. Patient (pt) characteristics and follow-up information were obtained from electronic medical records...
March 2017: Breast Journal
https://www.readbyqxmd.com/read/28298263/a-proof-of-principle-simulation-for-closed-loop-control-based-on-preexisting-experimental-thalamic-dbs-enhanced-instrumental-learning
#17
Ching-Fu Wang, Shih-Hung Yang, Sheng-Huang Lin, Po-Chuan Chen, Yu-Chun Lo, Han-Chi Pan, Hsin-Yi Lai, Lun-De Liao, Hui-Ching Lin, Hsu-Yan Chen, Wei-Chen Huang, Wun-Jhu Huang, You-Yin Chen
Deep brain stimulation (DBS) has been applied as an effective therapy for treating Parkinson's disease or essential tremor. Several open-loop DBS control strategies have been developed for clinical experiments, but they are limited by short battery life and inefficient therapy. Therefore, many closed-loop DBS control systems have been designed to tackle these problems by automatically adjusting the stimulation parameters via feedback from neural signals, which has been reported to reduce the power consumption...
February 24, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28297274/validation-of-an-improved-helical-diode-array-and-dose-reconstruction-software-using-tg-244-datasets-and-stringent-dose-comparison-criteria
#18
Saeed Ahmed, Benjamin Nelms, Jakub Kozelka, Geoffrey Zhang, Eduardo Moros, Vladimir Feygelman
The original helical ArcCHECK (AC) diode array and associated software for 3D measurement-guided dose reconstruction were characterized and validated; however, recent design changes to the AC required that the subject be revisited. The most important AC change starting in 2014 was a significant reduction in the overresponse of diodes to scattered radiation outside of the direct beam, accomplished by reducing the amount of high-Z materials adjacent to the diodes. This change improved the diode measurement accuracy, but in the process invalidated the dose reconstruction models that were assembled based on measured data acquired with the older version of the AC...
November 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28296390/clickable-antifouling-polymer-brushes-for-polymer-pen-lithography
#19
Uwe Bog, Andrés de Los Santos, Summer Mueller, Shana Havenridge, Viviana Parrillo, Michael Bruns, Andrea E Holmes, Cesar Rodriguez-Emmenegger, Harald Fuchs, Michael Hirtz
Protein-repellent reactive surfaces that promote localized specific binding are highly desirable for applications in the biomedical field. Nonspecific adhesion will compromise the function of bioactive surfaces, leading to ambiguous results of binding assays and negating the binding specificity of patterned cell-adhesive motives. Localized specific binding is often achieved by attaching a linker to the surface and the other side of the linker is used to bind specifically to a desired functional agent, as e...
March 15, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28295692/addressable-and-color-tunable-piezophotonic-light-emitting-stripes
#20
Yan Chen, Yang Zhang, Daniil Karnaushenko, Li Chen, Jianhua Hao, Fei Ding, Oliver G Schmidt
Piezophotonic light-emitting devices have great potential for future microelectromechanical systems (MEMS) and nanoelectromechanical systems (NEMS) due to the added functionality provided by the electromechanical transduction coupled with the ability of light emission. Piezophotonic light-emitting source based on Pb(Mg1/3 Nb2/3 )O3 -PbTiO3 (PMN-PT) bulk is severely restricted by many challenges, such as high voltage burden, low integration density, and micromanufacturing complexity. Developing chip-integrated devices or incorporating such photonic components onto a Si platform is highly sought after in this field...
March 15, 2017: Advanced Materials
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