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https://www.readbyqxmd.com/read/28547895/review-of-flexible-temperature-sensing-networks-for-wearable-physiological-monitoring
#1
REVIEW
Qiao Li, Li-Na Zhang, Xiao-Ming Tao, Xin Ding
Physiological temperature varies temporally and spatially. Accurate and real-time detection of localized temperature changes in biological tissues regardless of large deformation is crucial to understand thermal principle of homeostasis, to assess sophisticated health conditions, and further to offer possibilities of building a smart healthcare and medical system. Additionally, continuous temperature mapping in flexible and stretchable formats opens up many other potential areas, such as artificially electronic skins and reflection of emotional changes...
May 26, 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/28545888/delivering-safer-immunotherapies-for-cancer
#2
Lauren Milling, Yuan Zhang, Darrell J Irvine
Cancer immunotherapy is now a powerful clinical reality, with a steady progression of new drug approvals and a massive pipeline of additional treatments in clinical and preclinical development. However, modulation of the immune system can be a double-edged sword: Drugs that activate immune effectors are prone to serious non-specific systemic inflammation and autoimmune side effects. Drug delivery technologies have an important role to play in harnessing the power of immune therapeutics while avoiding on-target/off-tumor toxicities...
May 22, 2017: Advanced Drug Delivery Reviews
https://www.readbyqxmd.com/read/28545847/sources-and-behaviour-of-nitrogen-compounds-in-the-shallow-groundwater-of-agricultural-areas-poyang-lake-basin-china
#3
Evgeniya Soldatova, Natalia Guseva, Zhanxue Sun, Valeriy Bychinsky, Pascal Boeckx, Bai Gao
Nitrogen contamination of natural water is a typical problem for various territories throughout the world. One of the regions exposed to nitrogen pollution is located in the Poyang Lake basin. As a result of agricultural activity and dense population, the shallow groundwater of this area is characterised by a high concentration of nitrogen compounds, primarily NO3(-), with the concentration varying from 0.1mg/L to 206mg/L. Locally, high ammonium content occurs in the shallow groundwater with low reduction potential Eh (<100mV)...
May 17, 2017: Journal of Contaminant Hydrology
https://www.readbyqxmd.com/read/28545298/design-and-fabrication-of-a-novel-stimulus-feedback-anticorrosion-coating-featured-by-rapid-self-healing-functionality-for-protection-of-magnesium-alloy
#4
ChenDi Ding, JianHua Xu, Ling Tong, GuangCai Gong, Wei Jiang, JiaJun Fu
Corrosion potential stimulus-responsive smart nanocontainers (CP-SNCs), are designed and synthesized based on the installation of the supramolecular assemblies (bipyridinium ⊂ water-soluble pillar[5]arenes) onto the exterior surface of magnetic nanovehicles (Fe3O4@mSiO2), linked by disulfide linkers. The supramolecular assemblies with high binding affinity as gatekeepers effectively block the encapsulated organic corrosion inhibitor, 8-hydroxyquinoline (8-HQ), within the mesopores of Fe3O4@mSiO2. When the corrosion potential of magnesium alloy (-1...
May 26, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28545123/predictability-of-arousal-in-mouse-slow-wave-sleep-by-accelerometer-data
#5
Gustavo Zampier Dos Santos Lima, Sergio Roberto Lopes, Thiago Lima Prado, Bruno Lobao-Soares, George C do Nascimento, John Fontenele-Araujo, Gilberto Corso
Arousals can be roughly characterized by punctual intrusions of wakefulness into sleep. In a standard perspective, using human electroencephalography (EEG) data, arousals are associated to slow-wave rhythms and K-complex brain activity. The physiological mechanisms that give rise to arousals during sleep are not yet fully understood. Moreover, subtle body movement patterns, which may characterize arousals both in human and in animals, are usually not detectable by eye perception and are not in general present in sleep studies...
2017: PloS One
https://www.readbyqxmd.com/read/28544090/functional-tuning-of-the-catalytic-residue-pka-in-a-de-novo-designed-esterase
#6
Katharina Hiebler, Zsófia Lengyel, Carlos A Castañeda, Olga V Makhlynets
AlleyCatE is a de novo designed esterase that can be allosterically regulated by calcium ions. This artificial enzyme has been shown to hydrolyze p-nitrophenyl acetate (pNPA) and 4-nitrophenyl-(2-phenyl)-propanoate (pNPP) with high catalytic efficiency. AlleyCatE was created by introducing a single histidine residue (His(144) ) into a hydrophobic pocket of calmodulin. In this work, we explore the determinants of catalytic properties of AlleyCatE. We obtained the pKa value of the catalytic histidine using experimental measurements by NMR and pH rate profile and compared these values to those predicted from electrostatics pKa calculations (from both empirical and continuum electrostatics calculations)...
May 24, 2017: Proteins
https://www.readbyqxmd.com/read/28543038/central-voice-production-and-pathophysiology-of-spasmodic-dysphonia
#7
REVIEW
Niv Mor, Kristina Simonyan, Andrew Blitzer
OBJECTIVE: Our ability to speak is complex, and the role of the central nervous system in controlling speech production is often overlooked in the field of otolaryngology. In this brief review, we present an integrated overview of speech production with a focus on the role of central nervous system. The role of central control of voice production is then further discussed in relation to the potential pathophysiology of spasmodic dysphonia (SD). DATA SOURCES: Peer-review articles on central laryngeal control and SD were identified from PUBMED search...
May 23, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28538392/maculopapular-rash-after-intravitreal-injection-of-an-antivascular-endothelial-growth-factor-aflibercept-for-treating-age-related-macular-degeneration-a-case-report
#8
Norihiro Nagai, Mari Ibuki, Hajime Shinoda, Kaori Kameyama, Kazuo Tsubota, Yoko Ozawa
RATIONALE: Aflibercept, an anti-vascular endothelial growth factor (VEGF) drug, is used for treatment of colon cancer as well as retinal diseases, including wet age-related macular degeneration (AMD). It is injected into the vitreous cavity of eyes for treatment of AMD. Although vascular suppression-including cardiovascular events-and local infection related to the injection procedure are well-known potential adverse events, pathological immune responses after intravitreal aflibercept (IVA) injection have not been described...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28536507/dopamine-modulates-delta-gamma-phase-amplitude-coupling-in-the-prefrontal-cortex-of-behaving-rats
#9
Victoria Andino-Pavlovsky, Annie C Souza, Robson Scheffer-Teixeira, Adriano B L Tort, Roberto Etchenique, Sidarta Ribeiro
Dopamine release and phase-amplitude cross-frequency coupling (CFC) have independently been implicated in prefrontal cortex (PFC) functioning. To causally investigate whether dopamine release affects phase-amplitude comodulation between different frequencies in local field potentials (LFP) recorded from the medial PFC (mPFC) of behaving rats, we used RuBiDopa, a light-sensitive caged compound that releases the neurotransmitter dopamine when irradiated with visible light. LFP power did not change in any frequency band after the application of light-uncaged dopamine, but significantly strengthened phase-amplitude comodulation between delta and gamma oscillations...
2017: Frontiers in Neural Circuits
https://www.readbyqxmd.com/read/28536269/a-cognition-related-neural-oscillation-pattern-generated-in-the-prelimbic-cortex-can-control-operant-learning-in-rats
#10
Samuel Hernández-González, Celia Andreu-Sánchez, Miguel Ángel Martín-Pascual, Agnès Gruart, José María Delgado-García
The prelimbic (PrL) cortex constitutes one of the highest levels of cortical hierarchy dedicated to the execution of adaptive behaviors. We have identified a specific local field potential (LFP) pattern generated in the PrL cortex, associated with cognition-related behaviors, and used it to trigger the activation of a visual display on a touch screen as part of an operant conditioning task. Rats learned to increase the presentation rate of the selected theta/beta-gamma transition pattern across training sessions...
May 23, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28532653/hippocampal-ca1-local-field-potential-oscillations-induced-by-olfactory-cue-of-liked-food
#11
Nifareeda Samerphob, Dania Cheaha, Surapong Chatpun, Ekkasit Kumarnsit
Eating motivation is induced not only by negative energy balance but also food related cues. However, neural processing for acquisition of learned food preference remains to be established. This study aimed to identify hippocampal neural signaling in response to olfactory cue (chocolate scent) after completion of repetitive chocolate sessions. Male Swiss albino mice implanted with intracranial electrode into the hippocampus were used for local field potential (LFP) recording. Animals were given chocolate sessions (a piece of 2 g chocolate per each mouse to eat on day 1, 3, 5 and 7)...
May 19, 2017: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/28532356/probing-human-visual-deficits-with-functional-magnetic-resonance-imaging
#12
Stelios M Smirnakis
Much remains to be understood about visual system malfunction following injury. The resulting deficits range from dense, visual field scotomas to mild dysfunction of visual perception. Despite the predictive value of anatomical localization studies, much patient-to-patient variability remains regarding (a) perceptual abilities following injury and (b) the capacity of individual patients for visual rehabilitation. Visual field perimetry is used to characterize the visual field deficits that result from visual system injury...
October 14, 2016: Annual Review of Vision Science
https://www.readbyqxmd.com/read/28530191/green-synthesis-of-silver-nanoparticles-using-bovine-skin-gelatin-and-its-antibacterial-effect-on-clinical-bacterial-isolates
#13
Hosam I Salaheldin, Meshal H K Almalki, Gamal E H Osman
Nanoparticles are being increasingly used in day-to-day life. Therefore, concerns have been raised regarding their interactions with the surrounding environment. This study focused on a simple green method for synthesizing silver nanoparticles (Ag-NPs) in an autoclave at 15 psi (103 kPa) and 121°C. An aqueous solution of AgNO3 as a precursor of Ag-NPs and gelatin (type B) reducing and/or stabilizing (capping) agent were used. The effect of various AgNO3 concentrations of certain gelatin concentration and various gelatin concentrations at constant AgNO3 concentration, and autoclaving time, was studied...
June 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/28527594/whole-globe-biomechanics-using-high-field-mri
#14
Andrew P Voorhees, Leon C Ho, Ning-Jiun Jan, Huong Tran, Yolandi van der Merwe, Kevin Chan, Ian A Sigal
The eye is a complex structure composed of several interconnected tissues acting together, across the whole globe, to resist deformation due to intraocular pressure (IOP). However, most work in the ocular biomechanics field only examines the response to IOP over smaller regions of the eye. We used high-field MRI to measure IOP induced ocular displacements and deformations over the whole globe. Seven sheep eyes were obtained from a local abattoir and imaged within 48 h using MRI at multiple levels of IOP. IOP was controlled with a gravity perfusion system and a cannula inserted into the anterior chamber...
May 17, 2017: Experimental Eye Research
https://www.readbyqxmd.com/read/28527378/life-cycle-assessment-of-superheated-steam-drying-technology-as-a-novel-cow-manure-management-method
#15
Mohammadmatin Hanifzadeh, Zahra Nabati, Pairote Longka, Pomthong Malakul, Defne Apul, Dong-Shik Kim
Common methods of managing dairy manure are directly applying it to the farm field as a fertilizer. For direct application without any type of treatment, the majority of nutrients in the manure run off to the local river and lake during precipitation periods. The algae bloom is one of the environmental outcomes due to eutrophication of the lakes, which may jeopardize the quality of drinking water. In this study, superheated steam drying (SSD) technology is investigated as an alternative manure management method...
May 17, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28527312/low-energy-electron-potentiometry
#16
Johannes Jobst, Jaap Kautz, Maria Mytiliniou, Rudolf M Tromp, Sense Jan van der Molen
In a lot of systems, charge transport is governed by local features rather than being a global property as suggested by extracting a single resistance value. Consequently, techniques that resolve local structure in the electronic potential are crucial for a detailed understanding of electronic transport in realistic devices. Recently, we have introduced a new potentiometry method based on low-energy electron microscopy (LEEM) that utilizes characteristic features in the reflectivity spectra of layered materials [1]...
May 13, 2017: Ultramicroscopy
https://www.readbyqxmd.com/read/28526435/the-bidirectional-gut-brain-microbiota-axis-as-a-potential-nexus-between-traumatic-brain-injury-inflammation-and-disease
#17
Mark H Sundman, Nan-Kuei Chen, Vignesh Subbian, Ying-Hui Chou
As head injuries and their sequelae have become an increasingly salient matter of public health, experts in the field have made great progress elucidating the biological processes occurring within the brain at the moment of injury and throughout the recovery thereafter. Given the extraordinary rate at which our collective knowledge of neurotrauma has grown, new insights may be revealed by examining the existing literature across disciplines with a new perspective. This article will aim to expand the scope of this rapidly evolving field of research beyond the confines of the central nervous system (CNS)...
May 16, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28524727/e-cadherin-%C3%AE-catenin-complex-a-target-for-anticancer-and-antimetastasis-plants-plant-derived-compounds
#18
Majid Tafrihi, Roohollah Nakhaei Sistani
Plants reputed to have cancer-inhibiting potential and putative active components derived from those plants have emerged as an exciting new field in cancer study. Some of these compounds have cancer-inhibiting potential in different clinical staging levels, especially metastasis. A few of them which stabilize cell-cell adhesions are controversial topics. This review article introduces some effective herbal compounds that target E-cadherin/β-catenin protein complex. In this article, at first, we briefly review the structure and function of E-cadherin and β-catenin proteins, Wnt signaling pathway, and its target genes...
May 19, 2017: Nutrition and Cancer
https://www.readbyqxmd.com/read/28523911/cup-shaped-nanoantenna-arrays-for-zeptoliter-volume-biochemistry-and-plasmonic-sensing-in-the-visible-wavelengths-range
#19
Rokas Drevinskas, Tomas Rakickas, Algirdas Selskis, Lorenzo Rosa, Ramunas Valiokas
Although three-dimensional shaping of metallic nanostructures is an important strategy for control and manipulation of localized surface plasmon resonance (LSPR), its implementation in high-throughput, on-chip fabrication of plasmonic devices remains to be challenging. Here we demonstrate nanocontact-based large area fabrication of a novel, LSPR-active Au architecture consisting of periodic arrays of reduced symmetry nanoantennas having sub-50 nm, out-of-plane features. Namely, by combining nanosphere and molecular self-assembly processes we have patterned evaporated polycrystalline Au films for chemical etching of nanocups with controlled aspect ratios (an outer diameter d=100 nm, void volumes of 18 or 39 zeptoliters)...
May 19, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28523580/chemical-characterization-of-surface-snow-in-istanbul-nw-turkey-and-their-association-with-atmospheric-circulations
#20
Asli Baysal, Hakki Baltaci, Nil Ozbek, Orhan Destanoglu, Gul Sirin Ustabasi, Gulcin Gumus
The understanding of the impurities in natural snow is important in realizing its atmospheric quality, soil characteristics, and the pollution caused to the environment. Knowledge of the occurrence of major ions and trace metals in the snow in the megacity of Istanbul is very limited. This manuscript attempts to understand the origin of major soluble ions (fluoride, acetate, formate, chlorite, chloride, nitrite, chlorate, bromide, nitrate, sulfate, phosphate, and perchlorate) and some trace metals (Fe, Mn, Cd, Co, Ni, Pb, Zn, Cu) in winter surface snow, collected in Istanbul, Turkey...
June 2017: Environmental Monitoring and Assessment
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