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https://www.readbyqxmd.com/read/28222558/effects-of-gait-training-using-the-hybrid-assistive-limb%C3%A2-%C3%A2-in-recovery-phase-stroke-patients-a-2-month-follow-up-randomized-controlled-study
#1
Hiroki Watanabe, Ryohei Goto, Naoki Tanaka, Akira Matsumura, Hisako Yanagi
BACKGROUND: Gait training using the Hybrid Assistive Limb ® (HAL ®) may have beneficial effects on post-stroke gait function and independent walking. However, the long-term and medium-term efficacies of gait training using HAL ® in stroke patients remain unclear. OBJECTIVE: To compare the medium-term efficacy of gait training using a single-leg version of the Hybrid Assistive Limb ® (HAL ®) on the paretic side with conventional gait training (CGT) in recovery-phase stroke patients...
January 8, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28222556/is-there-influence-of-the-load-addition-during-treadmill-training-on-cardiovascular-parameters-and-gait-performance-in-patients-with-stroke-a-randomized-clinical-trial
#2
Tatiana Souza Ribeiro, Tállyta Camila Chaves da Silva, Renata Carlos Felipe, Emília Márcia Gomes de Souza E Silva, Matheus Oliveira Lacerda, Ana Paula Spaniol, Ana Raquel Rodrigues Lindquist
BACKGROUND: Although exercises involving both lower limbs are indicated for aerobic training, stroke patients have shown expressive asymmetry between the paretic and non-paretic lower limb (NPLL). Performing activities that stimulate the paretic limb during aerobic exercise may optimize training results. OBJECTIVE: To evaluate if there is influence of load addition on NPLL during treadmill training on cardiovascular parameters and gait performance of subacute stroke patients...
February 8, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28222555/effects-of-scapulohumeral-rehabilitation-protocol-on-trunk-control-recovery-in%C3%A2-patients-with-subacute-stroke-a%C3%A2-pilot%C3%A2-randomized-controlled-trial
#3
Dell'Uomo Daniela, Morone Giovanni, Centrella Antonio, Paolucci Stefano, Caltagirone Carlo, Grasso Maria Grazia, Traballesi Marco, Iosa Marco
BACKGROUND: Despite upper limb rehabilitation is widely investigated in patients with stroke, the effects of rehabilitation of scapulohumeral on trunk stabillization are mainly unknown. OBJECTIVE: To test the effects of scapulohumeral rehabilitation protocol on trunk control recovery in patients with subacute stroke. METHODS: A pilot randomized controlled trial with two groups of 14 patients each one performing 20 minutes per day, 5 days a week, for 6 weeks in add on to standard therapy...
February 8, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28222552/comparison-of-cognitive-orientation-to-daily-occupational-performance-and-conventional-occupational-therapy-on-occupational-performance-in-individuals-with-stroke-a-randomized-controlled-trial
#4
Si-Nae Ahn, Min-Ye Jung, Hae-Yean Park, Ji-Yeon Lee, Yoo-Im Choi, Eun-Young Yoo
BACKGROUND: Cognitive Orientation to daily Occupational Performance (CO-OP) approach based on cognitive strategy in occupational therapy. OBJECTIVES: To investigate the effects of CO-OP approach on occupational performance in individuals with hemiparetic stroke. METHODS: This study was designed as a 5-week, randomized, single-blind. Forty-three participants who had a diagnosis of first stroke were enrolled in this study. The participants were randomly assigned to the experimental group (n = 20) or the control group (n = 23)...
February 8, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28222534/a-meta-analysis-of-memantine-for%C3%A2-depression
#5
Taro Kishi, Shinji Matsunaga, Nakao Iwata
We conducted a systematic review and meta-analysis on whether memantine was beneficial for the treatment of depressive symptoms in major depressive disorder (MDD) and bipolar disorder (BD). The analysis included double-blind, randomized, placebo-controlled trials of memantine in MDD and BD. The primary outcome measures for efficacy and safety were response rate and all-cause discontinuation, respectively. Risk ratio (RR) and standardized mean difference with 95% confidence intervals (95% CI) were calculated...
February 10, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28222505/cognitive-training-interventions-for%C3%A2-patients-with-alzheimer-s-disease-a%C3%A2-systematic-review
#6
Eeva-Liisa Kallio, Hanna Öhman, Hannu Kautiainen, Marja Hietanen, Kaisu Pitkälä
BACKGROUND: Cognitive training (CT) refers to guided cognitive exercises designed to improve specific cognitive functions, as well as enhance performance in untrained cognitive tasks. Positive effects of CT on cognitive functions in healthy elderly people and persons with mild cognitive impairment have been reported, but data regarding the effects of CT in patients with dementia is unclear. OBJECTIVE: We systematically reviewed the current evidence from randomized controlled trials (RCTs) to find out if CT improves or stabilizes cognition and/or everyday functioning in patients with mild and moderate Alzheimer's disease...
February 7, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28222465/autologous-conditioned-plasma-versus-placebo-injection-therapy-in-lateral-epicondylitis-of-the-elbow-a-double-blind-randomized-study
#7
Volker Schöffl, Wolfgang Willauschus, Felix Sauer, Thomas Küpper, Isabelle Schöffl, Christoph Lutter, Kolja Gelse, Jörg Dickschas
Introduction There are various therapeutic approaches to the treatment of lateral epicondylitis, a highly prevalent musculoskeletal disorder. Recently, injection therapy with autologous conditioned plasma (ACP) has shown promise as a new approach. Methods Set up as a prospective, double-blind, randomized controlled clinical trial, this study involved 50 patients with lateral epicondylitis. Following external randomization, 25 patients received one round of injection therapy with ACP (platelet rich plasma, PRP), while the remaining 25 patients received a placebo of 0...
February 21, 2017: Sportverletzung Sportschaden: Organ der Gesellschaft Für Orthopädisch-Traumatologische Sportmedizin
https://www.readbyqxmd.com/read/28222422/impact-of-diet-and-or-exercise-intervention-on-infrapatellar-fat-pad-morphology-secondary-analysis-from-the-intensive-diet-and-exercise-for-arthritis-idea-trial
#8
Aarón Leonardo Pogacnik Murillo, Felix Eckstein, Wolfgang Wirth, Daniel Beavers, Richard F Loeser, Barbara J Nicklas, Shannon L Mihalko, Gary D Miller, David J Hunter, Stephen P Messier
OBJECTIVES: The infrapatellar fat pad (IPFP) represents intra-articular adipose tissue that may contribute to intra-articular inflammation and pain by secretion of proinflammatory cytokines. Here we examined the impact of weight loss by diet and/or exercise interventions on the IPFP volume. METHODS: Intensive Diet and Exercise for Arthritis (IDEA) was a single-blinded, single-center, 18-month, prospective, randomized controlled trial that enrolled 454 overweight and obese older adults with knee pain and radiographic osteoarthritis...
February 22, 2017: Cells, Tissues, Organs
https://www.readbyqxmd.com/read/28222370/increased-postural-sway-in-persons-with-multiple-sclerosis-during-short-term-exposure-to-warm-ambient-temperatures
#9
Paula Y S Poh, Amy N Adams, Mu Huang, Dustin R Allen, Scott L Davis, Anna S Tseng, Craig G Crandall
BACKGROUND: Multiple sclerosis (MS) is a neurological disease marked by demyelination and axonal loss. Individuals with MS experience increases in clinical signs and symptoms during heat exposure. OBJECTIVE: To test the hypothesis that moderate heat exposure adversely affects postural sway in individuals with MS. METHODS: Ten individuals with relapsing-remitting MS (50±8y) and nine controls (47±10y) were examined under a Thermal and a Time Control trial...
February 8, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28222360/maintenance-therapy-with-second-generation-antipsychotics-for-bipolar-disorder-a-systematic-review-and-meta-analysis
#10
REVIEW
Leif Lindström, Eva Lindström, Mikael Nilsson, Malin Höistad
BACKGROUND: Second generations antipsychotics (SGA) are frequently used for maintenance treatment in bipolar disorder. We systematically reviewed the efficacy and long-term effects of treatment with SGA, regardless of treatment strategy (SGA administered either as monotherapy or as adjunctive therapy), in comparison to placebo, lithium or valproate. Primary outcomes were relapses (mood episode recurrence) and discontinuation. METHOD: Clinical studies were identified through database searching in PubMed, Embase, PsychInfo and Cochrane Library and critically appraised based on the Cochrane Handbook...
February 14, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28222158/the-effect-of-anti-angiogenic-agents-on-overall-survival-in-metastatic-oesophago-gastric-cancer-a-systematic-review-and-meta-analysis
#11
David L Chan, Katrin M Sjoquist, David Goldstein, Timothy J Price, Andrew J Martin, Yung-Jue Bang, Yoon-Koo Kang, Nick Pavlakis
BACKGROUND: Studies of anti-angiogenic agents (AAs), combined with chemotherapy (chemo) or as monotherapy in metastatic oesophago-gastric cancer (mOGC), have reported mixed outcomes. We undertook systematic review and meta-analysis to determine their overall benefits and harms. METHODS: Randomized controlled trials in mOGC were sought investigating the addition of AAs to standard therapy (best supportive care or chemo). The primary endpoint was overall survival (OS) with secondary endpoints progression-free survival (PFS), overall response rate (ORR) and toxicity...
2017: PloS One
https://www.readbyqxmd.com/read/28222149/ultrasonographic-evaluation-of-urinary-tract-morbidity-in-school-aged-and-preschool-aged-children-infected-with-schistosoma-haematobium-and-its-evolution-after-praziquantel-treatment-a-randomized-controlled-trial
#12
Beatrice Barda, Jean T Coulibaly, Christoph Hatz, Jennifer Keiser
BACKGROUND: Schistosoma haematobium infections are responsible for significant urinary tract (UT) complications. Schistosomiasis control programs aim to reduce morbidity, yet the extent of morbidity in preschool-aged children and the impact of treatment on morbidity reduction are not well studied. METHODOLOGY: Our study was embedded in a randomized, placebo-controlled, single-blind trial in Côte d'Ivoire, which evaluated the efficacy and safety of three doses (20, 40 and 60 mg/kg) of praziquantel in school-aged (SAC) and preschool-aged (PSAC) children infected with S...
February 21, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28222101/costs-and-effects-of-a-state-wide-health-promotion-program-in-primary-schools-in-germany-the-baden-w%C3%A3-rttemberg-study-a-cluster-randomized-controlled-trial
#13
Dorothea Kesztyüs, Romy Lauer, Tibor Kesztyüs, Reinhold Kilian, Jürgen M Steinacker
AIM: To evaluate the cost-effectiveness of the state-wide implementation of the health promotion program "Join the Healthy Boat" in primary schools in Germany. METHODS: Cluster-randomized intervention trial with wait-list control group. Anthropometric data of 1733 participating children (7.1 ± 0.6 years) were taken by trained staff before and after a one year intervention period in the academic year 2010/11. Parents provided information about the health status, and the health behaviour of their children and themselves, parental anthropometrics, and socio-economic background variables...
2017: PloS One
https://www.readbyqxmd.com/read/28222084/african-american-women-s-recollected-experiences-of-adherence-to-breast-cancer-treatment
#14
Sue P Heiney, DeAnne K Hilfinger Messias, Tisha M Felder, Kenneth W Phelps, Jada C Quinn
PURPOSE/OBJECTIVES: To explore African American women's recollected experiences of breast cancer treatment.
. RESEARCH APPROACH: Qualitative description and narrative analysis.
. SETTING: South Carolina Oncology Associates, an outpatient oncology clinic serving rural and urban populations.
. PARTICIPANTS: 16 African American women with breast cancer previously enrolled in the control arm (n = 93) of a completed randomized, controlled trial...
March 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28222077/association-of-smoking-in-the-home-with-lung-cancer-worry-perceived-risk-and-synergistic-risk
#15
Karen M Butler, Mary Kay Rayens, Amanda T Wiggins, Kathy B Rademacher, Ellen J Hahn
PURPOSE/OBJECTIVES: To examine the association of smoking in the home with lung cancer worry, perceived risk, and synergistic risk, controlling for sociodemographics, family history of lung cancer, and health-related self-concept. The hypothesis is that participants with smoking in the home would have higher scores for lung cancer worry, perceived risk, and synergistic risk.
. DESIGN: Cross-sectional baseline survey. 
. SETTING: Participants recruited from an outpatient clinic and pharmacy at University of Kentucky HealthCare, an academic medical center...
March 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28221865/cost-effectiveness-of-immune-checkpoint-inhibition-in-braf-wild-type-advanced-melanoma
#16
Christine G Kohn, Simon B Zeichner, Qiushi Chen, Alberto J Montero, Daniel A Goldstein, Christopher R Flowers
Purpose Patients who are diagnosed with stage IV metastatic melanoma have an estimated 5-year relative survival rate of only 17%. Randomized controlled trials of recent US Food and Drug Administration-approved immune checkpoint inhibitors-pembrolizumab (PEM), nivolumab (NIVO), and ipilumumab (IPI)-demonstrate improved patient outcomes, but the optimal treatment sequence in patients with BRAF wild-type metastatic melanoma remains unclear. To inform policy makers about the value of these treatments, we developed a Markov model to compare the cost-effectiveness of different strategies for sequencing novel agents for the treatment of advanced melanoma...
February 21, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28221821/enhanced-neural-activation-with-blueberry-supplementation-in-mild-cognitive-impairment
#17
Erin L Boespflug, James C Eliassen, Jonathan A Dudley, Marcelle D Shidler, Wilhelmina Kalt, Suzanne S Summer, Amanda L Stein, Amanda N Stover, Robert Krikorian
OBJECTIVES: Preclinical studies have shown that blueberry supplementation can improve cognitive performance and neural function in aged animals and have identified associations between anthocyanins and such benefits. Preliminary human trials also suggest cognitive improvement in older adults, although direct evidence of enhancement of brain function has not been demonstrated. In this study, we investigated the effect of blueberry supplementation on regional brain activation in older adults at risk for dementia...
February 21, 2017: Nutritional Neuroscience
https://www.readbyqxmd.com/read/28221364/neuroprotection-after-a-first-episode-of-mania-a-randomized-controlled-maintenance-trial-comparing-the-effects-of-lithium-and-quetiapine-on-grey-and-white-matter-volume
#18
M Berk, O Dandash, R Daglas, S M Cotton, K Allott, A Fornito, C Suo, P Klauser, B Liberg, L Henry, C Macneil, M Hasty, P McGorry, Cs Pantelis, M Yücel
No abstract text is available yet for this article.
February 21, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28221300/patient-experience-of-wearing-compression-garments-post-burn-injury-a-review-of-the-literature
#19
Nicole Coghlan, Jodie Copley, Tammy Aplin, Jenny Strong
This review was conducted to critically appraise the literature regarding the patient's lived experience of, and adherence to, wearing compression garments post burn injury. Scholarly articles were identified from searches of the following databases: Pubmed, Cochrane Central, CINAHL, PsycINFO, and OT Seeker. Combinations of key words including compression therapy/garment, pressure therapy/garment, burn(s), adherence, and patient experience were utilized. Retrieved studies were included in the review if they were written in English, reported on adult burn populations, and the patient's lived experience of wearing compression garments...
February 16, 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/28221247/self-managed-ehealth-disease-monitoring-in-children-and-adolescents-with-inflammatory-bowel-disease-a-randomized-controlled-trial
#20
Katrine Carlsen, Christian Jakobsen, Gunnar Houen, Thomas Kallemose, Anders Paerregaard, Lene B Riis, Pia Munkholm, Vibeke Wewer
BACKGROUND: To evaluate the impact of eHealth on disease activity, the need for hospital contacts, and medical adherence in children and adolescents with inflammatory bowel disease (IBD). Furthermore, to assess eHealth's influence on school attendance and quality of life (QoL). METHODS: Patients with IBD, 10 to 17 years attending a public university hospital, were prospectively randomized to a 2-year open label case-controlled eHealth intervention. The eHealth-group used the web-application young...
March 2017: Inflammatory Bowel Diseases
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