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https://www.readbyqxmd.com/read/28634000/dose-dependent-effects-of-abobotulinumtoxina-dysport%C3%A2-on-spasticity-and-active-movements-in-adults-with-upper-limb-spasticity-secondary-analysis-of-a-phase-3-study
#1
Michael W O'Dell, Allison Brashear, Robert Jech, Thierry Lejeune, Philippe Marque, Djamel Bensmail, Ziyad Ayyoub, David M Simpson, Magali Volteau, Claire Vilain, Philippe Picaut, Jean Michel Gracies
BACKGROUND: AbobotulinumtoxinA has beneficial effects on spasticity and active movements in hemiparetic adults with upper limb spasticity (ULS). However, evidence-based information on optimal dosing for clinical use is limited. OBJECTIVE: To describe joint-specific dose effects of abobotulinumtoxinA in adults with ULS. DESIGN: Secondary analysis of a phase 3 study (NCT01313299). SETTING: Multi-center, international, double-blind, placebo-controlled clinical trial...
June 17, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28633117/breakup-characteristics-of-aqueous-droplet-with-surfactant-in-oil-under-direct-current-electric-field
#2
Xiaoming Luo, Haipeng Yan, Xin Huang, Donghai Yang, Jing Wang, Limin He
The breakup process of aqueous droplet with surfactant suspended in oil under direct current (DC) electric field is investigated in this paper. The characteristics of the breakup process, stretching, necking and breakup, are discussed quantitatively with the electric capillary number Ca and the dimensionless surfactant concentration C(∗) which is the ratio of surfactant concentration to the critical micelle concentration. The results show that the presence of surfactant reduces the steady deformation of droplet and significantly decelerates the stretching process, resulting from the redistribution of surfactant molecules within the oil/water interface...
June 13, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28629415/kaps-kinematic-assessment-of-passive-stretch-a-tool-to-assess-elbow-flexor-and-extensor-spasticity-after-stroke-using-a-robotic-exoskeleton
#3
Andrew Centen, Catherine R Lowrey, Stephen H Scott, Ting-Ting Yeh, George Mochizuki
BACKGROUND: Spasticity is a common sequela of stroke. Traditional assessment methods include relatively coarse scales that may not capture all characteristics of elevated muscle tone. Thus, the aim of this study was to develop a tool to quantitatively assess post-stroke spasticity in the upper extremity. METHODS: Ninety-six healthy individuals and 46 individuals with stroke participated in this study. The kinematic assessment of passive stretch (KAPS) protocol consisted of passive elbow stretch in flexion and extension across an 80° range in 5 movement durations...
June 19, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28628653/esperanza-window-traps-for-the-collection-of-anthropophilic-blackflies-diptera-simuliidae-in-uganda-and-tanzania
#4
Adam Hendy, Vincent Sluydts, Taylor Tushar, Jacobus De Witte, Patrick Odonga, Denis Loum, Michael Nyaraga, Thomson Lakwo, Jean-Claude Dujardin, Rory Post, Akili Kalinga, Richard Echodu
There is an increasing need to evaluate the impact of chemotherapeutic and vector-based interventions as onchocerciasis affected countries work towards eliminating the disease. The Esperanza Window Trap (EWT) provides a possible alternative to human landing collections (HLCs) for the collection of anthropophilic blackflies, yet it is not known whether current designs will prove effective for onchocerciasis vectors throughout sub-Saharan Africa. EWTs were deployed for 41 days in northern Uganda and south eastern Tanzania where different Simulium damnosum sibling species are responsible for disease transmission...
June 19, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28627917/functional-intimacy-needing-but-not-wanting-the-touch-of-a-stranger
#5
Juliana Schroeder, Ayelet Fishbach, Chelsea Schein, Kurt Gray
Intimacy is often motivated by love, but sometimes it is merely functional. For example, disrobing and being touched at an airport security check serves the goal of catching a flight, not building a relationship. We propose that this functional intimacy induces discomfort, making people prefer greater social distance from their interaction partner. Supporting this prediction, participants who considered (Experiments 1 and 2) or experienced (Experiment 3) more physically intimate medical procedures preferred a health provider who is less social...
June 19, 2017: Journal of Personality and Social Psychology
https://www.readbyqxmd.com/read/28626945/european-corn-borer-ostrinia-nubilalis-hbn-lepidoptera-crambidae-comparing-the-performance-of-a-new-bisexual-lure-with-that-of-synthetic-sex-pheromone-in-five-countries
#6
Miklós Tóth, István Szarukán, Antal Nagy, Lorenzo Furlan, Isadora Benvegnu, Magda Rak Cizej, Tamás Ábri, Tamás Kéki, Szilvia Körösi, Attila Pogonyi, Teodora Toshova, Dimitar Velchev, Daniela Atanasova, Alican Kurtulus, Bora Kaydan
BACKGROUND: Phenylacetaldehyde is a flower volatile and attractant among others also for the European corn borer Ostrinia nubilalis. The addition of 4-methoxyphenethyl alcohol has recently been reported to increase O. nubilalis catches 4 to 5 times, yielding a bisexual lure for the species. RESULTS: The bisexual lure significantly outperformed synthetic pheromone lures of O. nubilalis at 11 out of 13 experiments conducted in Bulgaria, Hungary, Italy, Slovenia and Turkey...
June 19, 2017: Pest Management Science
https://www.readbyqxmd.com/read/28626279/nutritional-status-of-foster-children-in-the-u-s-implications-for-cognitive-and-behavioral-development
#7
Ursula A Tooley, Zeina Makhoul, Philip A Fisher
OBJECTIVE: Children in foster care are at greater risk for poor health, physical, cognitive, behavioral, and developmental outcomes than are children in the general population. Considerable research links early nutrition to later cognitive and behavioral outcomes. The aim of this narrative review is to examine the prevalence of poor nutrition and its relation to subsequent health and development in foster children. METHOD: Relevant studies for inclusion were identified from numerous sources (e...
November 2016: Children and Youth Services Review
https://www.readbyqxmd.com/read/28625945/hiv-treatment-catching-up-is-a-priority-in-west-and-central-africa
#8
P Lepère, J-M Milleliri
No abstract text is available yet for this article.
June 19, 2017: Médecine et Santé Tropicales
https://www.readbyqxmd.com/read/28625926/prenatal-caffeine-exposure-induced-high-susceptibility-to-metabolic-syndrome-in-adult-female-offspring-rats-and-its-underlying-mechanisms
#9
Lin-Guo Pei, Chao Yuan, Yi-Tian Guo, Hao Kou, Li-Ping Xia, Li Zhang, You-E Yan, Dan Xu, Hui Wang
Our previous studies have demonstrated that prenatal caffeine exposure (PCE) induced an intrauterine programming of hypothalamic-pituitary-adrenal axis (HPAA)-associated neuroendocrine metabolism in 3-month-old offspring rats. In this study, we aimed to confirm this programming disorder and high susceptibility to metabolic syndrome (MS) in 10-month-old female PCE offspring with postnatal catch-up growth. We found that PCE female offspring rats showed decreased bodyweight but a higher rate of weight gain after birth...
June 15, 2017: Reproductive Toxicology
https://www.readbyqxmd.com/read/28622781/-iron-requirements-during-the-first-6-months-of-life
#10
A Lapillonne, O Becquet
Because of the postnatal redistribution of the iron store, the term infant born after an uneventful pregnancy virtually needs no iron during its first 6 months of life. On the other hand, several factors, such as duration of gestation, gender, mother's iron status, alteration of the iron placental transfer, significantly influence the iron store at birth. Because of their reduced body store at birth and their higher demand during catch-up growth, low birth weight infants should receive an iron supplement, which should be started earlier and given at a higher dose in the more premature infants...
May 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/28622759/catching-audiovisual-interactions-with-a-first-person-fisherman-video-game
#11
Yile Sun, Timothy J Hickey, Barbara Shinn-Cunningham, Robert Sekuler
The human brain is excellent at integrating information from different sources across multiple sensory modalities. To examine one particularly important form of multisensory interaction, we manipulated the temporal correlation between visual and auditory stimuli in a first-person fisherman video game. Subjects saw rapidly swimming fish whose size oscillated, either at 6 or 8 Hz. Subjects categorized each fish according to its rate of size oscillation, while trying to ignore a concurrent broadband sound seemingly emitted by the fish...
July 2017: Perception
https://www.readbyqxmd.com/read/28622724/porphyrin-arch-tapes-synthesis-contorted-structures-and-full-conjugation
#12
Norihito Fukui, Taeyeon Kim, Dongho Kim, Atsuhiro Osuka
Porphyrin tapes possessing meso-meso β-β β-β triple direct linkages have been targets of extensive studies because of their fully conjugated characteristic π-electronic networks. In this paper, we report porphyrin arch-tapes that bear additional carbonyl group(s) or methylene group(s) inserted between one of the β-β linkage(s) of the porphyrin tapes. The carbonyl-inserted porphyrin arch-tapes were efficiently synthesized by double fusion reactions of β-to-β carbonyl-bridged porphyrin oligomers with DDQ and Sc(OTf)3, and were converted to the methylene-bridged porphyrin arch-tapes via Luche reduction with NaBH4 and CeCl3 followed by ionic hydrogenation with HBF4·OEt2 and BH3·NEt3...
June 16, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28621979/model-of-cell-crawling-controlled-by-mechanosensitive-adhesion
#13
M Leoni, P Sens
We study the motility of model cells and biomimetic soft objects crawling over a substrate covered with adhesive linkers. The cell exerts traction forces on the substrate through the active periodic motion of molecular complexes to which the linkers bind and unbind stochastically. We first show that the diffusion coefficient of a force dipole (unable by symmetry to perform directed motion) is maximal for a finite ratio of the unbinding to binding rates, highlighting the role of adhesion kinetics on cell translocation...
June 2, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28621794/exploring-surface-landscapes-with-molecules-rotationally-induced-diffraction-of-h2-on-lif-001-under-fast-grazing-incidence-conditions
#14
M Del Cueto, A S Muzas, M F Somers, G J Kroes, C Díaz, F Martín
Atomic diffraction by surfaces under fast grazing incidence conditions has been used for almost a decade to characterize surface properties with more accuracy than with more traditional atomic diffraction methods. From six-dimensional solutions of the time-dependent Schrödinger equation, we show that diffraction of H2 molecules under fast grazing incidence conditions could be even more informative for the characterization of ionic surfaces, due to the large anisotropic electrostatic interaction between the quadrupole moment of the molecule and the electric field created by the ionic crystal...
June 16, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28621001/early-vocabulary-development-in-children-with-bilateral-cochlear-implants
#15
Taina Välimaa, Sari Kunnari, Päivi Laukkanen-Nevala, Eila Lonka
BACKGROUND: Children with unilateral cochlear implants (CIs) may have delayed vocabulary development for an extended period after implantation. Bilateral cochlear implantation is reported to be associated with improved sound localization and enhanced speech perception in noise. This study proposed that bilateral implantation might also promote early vocabulary development. Knowledge regarding vocabulary growth and composition in children with bilateral CIs and factors associated with it may lead to improvements in the content of early speech and language intervention and family counselling...
June 16, 2017: International Journal of Language & Communication Disorders
https://www.readbyqxmd.com/read/28620347/neural-consequences-of-chronic-short-sleep-reversible-or-lasting
#16
REVIEW
Zhengqing Zhao, Xiangxiang Zhao, Sigrid C Veasey
Approximately one-third of adolescents and adults in developed countries regularly experience insufficient sleep across the school and/or work week interspersed with weekend catch up sleep. This common practice of weekend recovery sleep reduces subjective sleepiness, yet recent studies demonstrate that one weekend of recovery sleep may not be sufficient in all persons to fully reverse all neurobehavioral impairments observed with chronic sleep loss, particularly vigilance. Moreover, recent studies in animal models demonstrate persistent injury to and loss of specific neuron types in response to chronic short sleep (CSS) with lasting effects on sleep/wake patterns...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28620245/catching-up-the-educational-mobility-of-migrants-and-natives-children-in-europe
#17
Doris Oberdabernig, Alyssa Schneebaum
Migrants into European countries are often less educated than European natives. We analyse whether migrants' children are more or less likely than natives' children to achieve upward educational mobility across generations, and study differences in the factors, which contribute to differences in mobility for the two groups. We find that migrants' descendants are more often upwardly mobile (and less often downwardly mobile) than their native peers in the majority of countries studied, and show that the main factor contributing to these patterns is the education level of parents...
August 9, 2017: Applied Economics
https://www.readbyqxmd.com/read/28618045/clean-catch-urine-collection-time-taken-and-diagnostic-implication-a-prospective-observational-study
#18
Shidan Tosif, Jonathan Kaufman, Patrick Fitzpatrick, Sandy M Hopper, Monsurul Hoq, Susan Donath, Franz E Babl
AIM: Clean catch urine (CCU) collection is commonly used in pre-continent children. CCU can be time-consuming and specimens may be contaminated. Our aim was to determine the time taken for CCU attempts and to describe the success of this method in diagnosing or excluding urinary tract infection. METHODS: Prospective observational study of CCU in pre-continent children aged 2-48 months in the emergency department. Time taken until urine collection, 'successful' (voided and caught), 'missed' (voided not caught) or the procedure 'stopped', were recorded and urine culture results analysed...
June 15, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28615352/preparatory-responses-to-socially-determined-mutually-exclusive-possibilities-in-chimpanzees-and-children
#19
Thomas Suddendorf, Jessica Crimston, Jonathan Redshaw
The capacity to imagine and prepare for alternative future possibilities is central to human cognition. Recent research suggests that between age 2 and 4 children gradually begin to demonstrate a capacity to prepare for two simple, mutually exclusive alternatives of an immediate future event. When children were given the opportunity to catch a target an experimenter dropped into an inverted Y-shaped tube, 2-year olds-as well as great apes-tended to cover only one of the exits, whereas 4-year-olds spontaneously and consistently prepared for both possible outcomes...
June 2017: Biology Letters
https://www.readbyqxmd.com/read/28615109/study-of-guided-wave-propagation-on-a-plate-between-two-solid-bodies-with-imperfect-contact-conditions
#20
A J Balvantín, J A Diosdado-De-la-Peña, P A Limon-Leyva, E Hernández-Rodríguez
In this work, fundamental symmetric Lamb wave S0 mode is characterized in terms of its velocity variation as function of the interfacial conditions between solid bodies in contact. Imperfect contact conditions are numerically and experimentally determined by using ultrasonic Lamb wave propagation parameters. For the study, an experimental system was used, formed by two solid aluminum rods (25.4mm in diameter) axially loading a thin aluminum plate to control contact interfacial stiffness. The axially applied load on the aluminum plate was varied from 0MPa to 10MPa...
June 3, 2017: Ultrasonics
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