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Aortic valve repair

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https://www.readbyqxmd.com/read/28203542/robotic-trans-atrial-and-trans-mitral-ventricular-septal-resection
#1
REVIEW
W Randolph Chitwood
Localized ventricular septal hypertrophy, also known as idiopathic hypertrophic subaortic stenosis or idiopathic hypertrophic subaortic septal obstruction (IHSS), can create severe ventricular outflow obstruction. This often results in a high sub-aortic pressure gradient with potentially lethal symptoms. In 1960, Braunwald described the hemodynamic characteristics of IHSS, and thereafter, Morrow developed a trans-aortic approach to resect a large part of the ventricular septum, enlarging the outflow tract. The Morrow operation has remained the gold standard for surgically treating this pathology...
January 2017: Annals of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28203538/robotic-mitral-valve-repair-for-degenerative-posterior-leaflet-prolapse
#2
Hoda Javadikasgari, Rakesh M Suri, Bassman Tappuni, Ashley M Lowry, Tomislav Mihaljevic, Stephanie Mick, A Marc Gillinov
BACKGROUND: Robotic mitral valve (MV) repair is the least invasive surgical approach to the MV and provides unparalleled access to the valve. We sought to assess technical aspects and clinical outcomes of robotic MV repair for isolated posterior leaflet prolapse by examining the first 623 such cases performed in a tertiary care center. METHODS: We reviewed the first 623 patients (mean age 56±9.7 years) with isolated posterior leaflet prolapse who underwent robotic primary MV repair from 01/2006 to 11/2013...
January 2017: Annals of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28198528/the-expression-of-inhibitor-of-nuclear-factor-kappa-b-kinase-epsilon-ikk%C3%AE%C2%B5-in-human-aortic-aneurysm
#3
Leiyang Zhang, Lei Wang, Wen Chen, Yueyue Xu, Liming Wang, Reinard Iskandar, Yifei Wang, Xin Chen
BACKGROUND: Aortic aneurysm (AA) is one of the most common causes of sudden death among elderly people. Although AA can be detected by non-invasive imaging techniques, there are no pharmacological treatments currently available to prevent progression at any stage of the disease. In this study we will explore the expression of IKKε in AA and its potential underlying molecular mechanism in AA. Material s and methods: Human aortic tissue was taken from 14 patients who underwent surgical repair of AA for the AA group and another 11 patients with normal aorta who underwent aortic valve replacement surgery for the control group...
February 15, 2017: Folia Morphologica (Warsz)
https://www.readbyqxmd.com/read/28190605/the-importance-of-age-and-weight-on-cavopulmonary-shunt-stage-ii-outcomes-after-the-norwood-procedure-planned-versus-unplanned-surgery
#4
David J Barron, Intisar Ul Haq, Adrian Crucean, John Stickley, Phil Botha, Natasha Khan, Timothy J Jones, William J Brawn
OBJECTIVE: The study objective was to evaluate the outcomes of the cavopulmonary shunt after the Norwood procedure with a particular focus on age, weight, and whether surgery was planned or expedited by clinical findings. METHODS: We studied 297 consecutive patients with hypoplastic left heart syndrome undergoing the cavopulmonary shunt operation between 2002 and 2014. All patients underwent the Norwood procedure with a right ventricle to pulmonary artery conduit...
January 17, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28187973/remodeling-root-repair-with-an-external-aortic-ring-annuloplasty
#5
Emmanuel Lansac, Isabelle Di Centa, Ghassan Sleilaty, Stephanie Lejeune, Alain Berrebi, Pavel Zacek, Mathieu Debauchez
OBJECTIVE: Although the remodeling technique provides the most dynamic valve-sparing root replacement, a dilated annulus (>25 mm) is a risk factor for failure. Aortic annuloplasty aims to reduce the annulus diameter, thus increasing coaptation height to protect the repair. The results of 177 patients with remodeling and external aortic ring annuloplasty were studied. METHODS: Data were collected from the Aortic Valve repair InternATiOnal Registry. Preoperative aortic insufficiency grade 3 or greater was present in 79 patients (44...
January 11, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28179972/septic-shock-of-unknown-origin-a-case-report-of-a-pseudoaneurysm-of-the-mitral-aortic-intervalvular-fibrosa
#6
Julio Gil, Hugo Antunes, Bruno Marmelo, Luis Abreu, Maria Luisa Goncalves, Luis Ferreira Dos Santos, Jose Costa Cabral
Pseudoaneurysm of the mitral-aortic intervalvular fibrosa (P-MAIVF) is a rare complication of infective endocarditis and trauma, particularly of aortic valve surgery. Clinical symptoms are usually unspecific and generally due to complications. Transesophageal echocardiography (TEE) is the most commonly used exam to diagnose P-MAIVF. The main echocardiographic feature is the presence of a cavity communicating with the left ventricular outflow tract that expands during systole and collapses during diastole. Most frequent complications are formation of a fistulous tract and compression of adjacent structures...
March 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28168982/two-decades-of-experience-with-root-remodeling-and-valve-repair-for-bicuspid-aortic-valves
#7
Ulrich Schneider, Susanne K Feldner, Christopher Hofmann, Jakob Schöpe, Stefan Wagenpfeil, Christian Giebels, Hans-Joachim Schäfers
OBJECTIVE: Bicuspid aortic valve anatomy is associated with ascending aortic aneurysm in approximately 50% of individuals and may lead to severe aortic regurgitation with aortic dilatation. Both entities may be treated by valve repair and root remodeling. The objective was to review the cumulative experience of 20 years. METHODS: Between November 1995 and December 2015, 357 patients (324 male; age 10-80 years; mean, 49 ± 13 years) underwent combined bicuspid aortic valve repair and root remodeling...
January 10, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28167695/interventional-repair-of-pseudoaneurysm-of-ascending-aorta-following-prosthetic-aortic-valve-replacement
#8
Amer Harky, Amir Khosravi, Jonathan Colledge, Shyamsunder Kolvekar
No abstract text is available yet for this article.
February 6, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28162223/impact-of-subclinical-vascular-complications-detected-by-systematic-postprocedural-multidetector-computed-tomography-after-transcatheter-aortic-valve-implantation-using-balloon-expandable-edwards-sapien-xt-heart-valve
#9
Yuki Kakefuda, Kentaro Hayashida, Yoshitake Yamada, Fumiaki Yashima, Taku Inohara, Ryo Yanagisawa, Makoto Tanaka, Takahide Arai, Takashi Kawakami, Yuichiro Maekawa, Hikaru Tsuruta, Yuji Itabashi, Mitsushige Murata, Motoaki Sano, Kazuma Okamoto, Akihiro Yoshitake, Hideyuki Shimizu, Masahiro Jinzaki, Keiichi Fukuda
Complications after transcatheter aortic valve implantation (TAVI) remain an important issue. This study aimed to evaluate the impact of systematic postprocedural multidetector computed tomography (MDCT) to detect subclinical complications after TAVI. From October 2013 to August 2015, a total of 135 patients who underwent transfemoral TAVI (n = 116) or transapical TAVI (n = 19) with Sapien XT and MDCT preprocedure and postprocedure were enrolled. Postprocedural MDCT findings were compared with the preprocedural MDCT findings...
January 5, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28159509/human-pericardial-fluid-contains-exosomes-enriched-with-cardiovascular-expressed-micrornas-and-promotes-therapeutic-angiogenesis
#10
Cristina Beltrami, Marie Besnier, Saran Shantikumar, Andrew I U Shearn, Cha Rajakaruna, Abas Laftah, Fausto Sessa, Gaia Spinetti, Enrico Petretto, Gianni D Angelini, Costanza Emanueli
The pericardial fluid (PF) is contained in the pericardial sac surrounding the heart. MicroRNA (miRNA) exchange via exosomes (endogenous nanoparticles) contributes to cell-to-cell communication. We investigated the hypotheses that the PF is enriched with miRNAs secreted by the heart and that it mediates vascular responses through exosome exchange of miRNAs. The study was developed using leftover material from aortic valve surgery. We found that in comparison with peripheral plasma, the PF contains exosomes enriched with miRNAs co-expressed in patients' myocardium and vasculature...
February 1, 2017: Molecular Therapy: the Journal of the American Society of Gene Therapy
https://www.readbyqxmd.com/read/28132534/intraoperative-diagnosis-of-a-quadricuspid-aortic-valve
#11
Hassan Tatari, Maziar Gholampour Dehaki, Gholamreza Omrani, Hafez Ghaheri, Alwaleed Al-Dairy, Hojjat Mortezaeian
Quadricuspid aortic valve is a rare anomaly, and most patients require surgery for aortic regurgitation in the 5th or 6th decades of life; only a few cases of aortic valve repair in childhood have been reported. A 3-year-old boy was scheduled for ventricular septal defect closure and aortic valve repair. Quadricuspid aortic valve was an incidental finding at operation; it was repaired by joining the left anterior and right anterior cusps. At the 9-month follow-up, the patient had no more than mild aortic regurgitation...
January 1, 2017: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/28132395/fatal-neisseria-macacae-infective-endocarditis-first-report
#12
Maude Vecten, Hélène Martel, Jean-Paul Casalta, Sandrine Hubert, Hubert Lepidi, Gilbert Habib, Didier Raoult, Frédérique Gouriet
INTRODUCTION: Neisseria macacae is a Gram-negative diplococcus, found in the oropharynx of healthy Rhesus Monkeys. Infections caused by N. macacae in humans are extremely rare. CASE PRESENTATION: We present here the first case of N. macacae infective endocarditis in a 65-year-old man with a native aortic valve infection complicated by a peri-aortic abscess. N. macacae was isolated from blood culture and was found on the cardiac valve using 16S rDNA detection. Despite an appropriate antibiotic therapy, and aortic homograft replacement, and mitral repair, the patient died 4 days after surgery from a massive hemorrhagic stroke...
January 28, 2017: Infection
https://www.readbyqxmd.com/read/28117617/patterns-and-determinants-of-functional-and-absolute-iron-deficiency-in-patients-undergoing-cardiac-rehabilitation-following-heart-surgery
#13
Roberto Tramarin, Valeria Pistuddi, Luigi Maresca, Marco Pavesi, Serenella Castelvecchio, Lorenzo Menicanti, Carlo de Vincentiis, Marco Ranucci
Background Anaemia and iron deficiency are frequent following major surgery. The present study aims to identify the iron deficiency patterns in cardiac surgery patients at their admission to a cardiac rehabilitation programme, and to determine which perioperative risk factor(s) may be associated with functional and absolute iron deficiency. Design This was a retrospective study on prospectively collected data. Methods The patient population included 339 patients. Functional iron deficiency was defined in the presence of transferrin saturation <20% and serum ferritin ≥100 µg/l...
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/28111369/triple-valve-surgery-through-a-less-invasive-approach-early-and-mid-term-results
#14
Petar Risteski, Nadejda Monsefi, Aleksandra Miskovic, Tanja Josic, Sherife Bala, Razan Salem, Andreas Zierer, Anton Moritz
OBJECTIVES: A partial upper sternotomy has become established as a less invasive approach mainly for single and double valve surgery. This report evaluates the clinical outcomes of triple valve surgery performed through a partial upper sternotomy. METHODS: We reviewed the medical records of 37 consecutive patients (28 men, 76%) who underwent triple valve surgery through a partial upper sternotomy between 2005 and 2015. The patients' mean age was 67 ± 17 years; 27 (73%) were in New York Heart Association Class III or IV...
January 22, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28110071/living-nano-micro-fibrous-woven-fabric-hydrogel-composite-scaffolds-for-heart-valve-engineering
#15
Shaohua Wu, Bin Duan, Xiaohong Qin, Jonathan T Butcher
: Regeneration and repair of injured or diseased heart valves remains a clinical challenge. Tissue engineering provides a promising treatment approach to facilitate living heart valve repair and regeneration. Three-dimensional (3D) biomimetic scaffolds that possess heterogeneous and anisotropic features that approximate those of native heart valve tissue are beneficial to the successful in vitro development of tissue engineered heart valves (TEHV). Here we report the development and characterization of a novel composite scaffold consisting of nano- and micro-scale fibrous woven fabrics and 3D hydrogels by using textile techniques combined with bioactive hydrogel formation...
January 18, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28108755/measurement-of-aortic-valve-coaptation-and-effective-height-using-echocardiography-in-patients-with-ventricular-septal-defects-and-aortic-valve-prolapse
#16
Satoru Iwashima, Hiroki Uchiyama, Takamichi Ishikawa, Kiyohiro Takigiku, Ken Takahashi, Manatomo Toyono, Nao Inoue, Masaki Nii
Decreased coaptation height in adults has been identified as a marker of early valve failure. We evaluated aortic valve coaptation and effective height in healthy children and in children with a ventricular septal defect (VSD) with aortic cusp prolapse (ACP), using echocardiography. We included 45 subjects with VSD with ACP, 27 did not develop aortic regurgitation (AR) by ACP and 18 developed AR by ACP, and 83 healthy children as controls. Aortic root anatomy was estimated using the parasternal long-axis view...
January 21, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28108579/surgical-repair-of-ostial-obstruction-of-the-coronary-artery-for-quadricuspid-aortic-valve-in-an-infant
#17
Takeaki Harada, Koji Fukae, Yusuke Ando
A congenital quadricuspid aortic valve accompanied by ostial obstruction of the left coronary artery is extremely rare and has not yet been reported in an infant. We herein describe an infant with ostial obstruction of the left coronary artery caused by a small left coronary cusp that formed a pouch. The patient's cardiac function deteriorated due to progressive myocardial ischaemia, and translocation of the ostium of the left coronary artery was performed. Postoperative coronary angiography revealed good filling of the left coronary artery...
January 20, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28106967/mitral-valve-repair-and-aortic-valve-replacement-with-sutureless-prosthesis-implantation-through-a-right-minithoracotomy
#18
Antonio Lio, Antonio Miceli, Matteo Ferrarini, Mattia Glauber
Little experience exists in minimally invasive treatment of double-valve disease. In this report, we present a minimally invasive approach for mitral and aortic valve disease through a minithoracotomy in the 3rd intercostal space with a sutureless aortic prosthesis implantation.
December 14, 2016: Multimedia Manual of Cardiothoracic Surgery: MMCTS
https://www.readbyqxmd.com/read/28104197/simplified-mitral-valve-repair-in-pediatric-patients-with-connective-tissue-disorders
#19
Luca A Vricella, William A Ravekes, Eloisa Arbustini, Robert D B Jaquiss, Constantine Mavroudis, Harry C Dietz, Marshall L Jacobs, Narutoshi Hibino, Duke E Cameron
BACKGROUND: In pediatric patients with connective tissue disorders (CTDs), early cardiac presentation often involves severe mitral regurgitation (MR) associated with severe bileaflet prolapse and, less frequently, aortic root enlargement. We adopted a simplified repair to address MR and prevent systolic anterior motion (SAM) in this unique group of patients. MATERIALS AND METHODS: Retrospective review of clinical and echocardiographic data of all pediatric patients (age < 18 years) with CTD and MR undergoing simplified repair at 3 institutions (2000-2014)...
February 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28100977/preserving-a-well-functioning-33-year-old-starr-edwards-aortic-prosthesis-in-repeat-aortic-root-aneurysm-repair
#20
Abdallah K Alameddine, Victor K Alimov, John A Rousou, Fabrizio I Pluchino
We report the case of a 61-year-old obese male patient in whom we found a well-functioning 33-year-old Starr-Edwards aortic prosthesis during repeat aortic surgery. Rather than explant the prosthesis, we remodeled the aortic root, almost completely removing the aortic sinuses and leaving only a pillar of aortic tissue around the coronary ostia. The proximal end of a Hemashield tube-graft was then scalloped to accommodate the remaining aortic tissue. The patient's heart function was excellent after his weaning from cardiopulmonary bypass...
December 2016: Texas Heart Institute Journal
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