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https://www.readbyqxmd.com/read/27922216/seven-elements-important-to-successful-implementation-of-early-literacy-intervention
#1
Barbara Foorman, Jennifer Dombek, Kevin Smith
The objective of this article is to describe seven elements important to successful implementation of early literacy intervention. The seven elements are drawn from research as well as from the authors' recent randomized controlled trial of effective early literacy interventions in kindergarten through second grade in 55 schools across Florida. The seven elements are (a) the importance of researcher-practitioner partnerships; (b) determining the need for early intervention; (c) assessment selection and data use; (d) evaluating curriculum and instructional materials for use in early intervention; (e) scheduling time for intervention; (f) selecting, training, and supporting interventionists; and (g) locating space and maintaining open communications among interventionists, teachers, and parents...
December 2016: New Directions for Child and Adolescent Development
https://www.readbyqxmd.com/read/27922214/implementation-challenges-for-tier-one-and-tier-two-school-based-programs-for-early-adolescents
#2
Maria D LaRusso, Suzanne Donovan, Catherine Snow
This mixed-method study examined the implementation and the challenges to implementation for participants in randomized controlled trials of two school-based programs for early adolescents: the Tier One Word Generation (WG) program, and the Tier Two Strategic Adolescent Reading Intervention (STARI). Levels of implementation for WG and STARI varied substantially across teachers and classrooms, with mean levels of 40% for fourth- and fifth-grade WG, 31% for sixth- and seventh-grade WG, and 47% for STARI. The three most common implementation challenges for WG were lack of time, multiple new programs/curricula happening at the same time, and time lost to testing and test prep...
December 2016: New Directions for Child and Adolescent Development
https://www.readbyqxmd.com/read/27922030/histamine-2-receptor-antagonist-cannot-prevent-recurrent-peptic-ulcers-in-patients-with-atherosclerotic-diseases-who-receive-platelet-adp-receptor-antagonist-monotherapy-a-randomized-controlled-double-blind-and-double-dummy-trial
#3
Ping-I Hsu, Deng-Chyang Wu, Feng-Woei Tsay, Jin-Shiung Cheng, Chun-Peng Liu, Kwok-Hung Lai, Wen-Chi Chen, Huay-Min Wang, Tzung-Jiun Tsai, Kuo-Wang Tsai, Sung-Shuo Kao
OBJECTIVES: Proton pump inhibitor can effectively prevent recurrent peptic ulcers among atherosclerotic patients receiving clopidogrel monotherapy. However, the interaction between proton pump inhibitors and clopidogrel has raised concerns over the safety of combined use of the two medicines in clinical practice. The aims of this randomized-controlled, double-blind and double-dummy trial were to investigate the efficacy of histamine-2 receptor antagonist (H2RA) in the prevention of recurrent peptic ulcer in patients undergoing thienopyridine monotherapy...
December 6, 2016: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/27922028/a-randomized-double-blind-placebo-controlled-trial-to-examine-the-effectiveness-of-lubiprostone-on-constipation-symptoms-and-colon-transit-time-in-diabetic-patients
#4
Jennifer Christie, Sagar Shroff, Nikrad Shahnavaz, Latoya A Carter, Melanie S Harrison, Karan A Dietz-Lindo, John Hanfelt, Shanthi Srinivasan
OBJECTIVES: Constipation is the most common GI symptom in patients with diabetes mellitus (DM). Importantly, patients with constipation have lower health-related quality of life than those without constipation. Effective therapies for constipation are limited and there is a paucity of data evaluating the treatment of constipation in diabetics. METHODS: Diabetic patients with chronic idiopathic constipation (CIC) as defined by Rome III criteria were recruited from outpatient clinics at a tertiary-care center and a Veterans Administration Hospital...
December 6, 2016: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/27922026/percutaneous-gastrostomy-device-for-the-treatment-of-class-ii-and-class-iii-obesity-results-of-a-randomized-controlled-trial
#5
Christopher C Thompson, Barham K Abu Dayyeh, Robert Kushner, Shelby Sullivan, Alan B Schorr, Anastassia Amaro, Caroline M Apovian, Terrence Fullum, Amir Zarrinpar, Michael D Jensen, Adam C Stein, Steven Edmundowicz, Michel Kahaleh, Marvin Ryou, J Matthew Bohning, Gregory Ginsberg, Christopher Huang, Daniel D Tran, Joseph P Glaser, John A Martin, David L Jaffe, Francis A Farraye, Samuel B Ho, Nitin Kumar, Donna Harakal, Meredith Young, Catherine E Thomas, Alpana P Shukla, Michele B Ryan, Miki Haas, Heidi Goldsmith, Jennifer McCrea, Louis J Aronne
OBJECTIVES: The AspireAssist System (AspireAssist) is an endoscopic weight loss device that is comprised of an endoscopically placed percutaneous gastrostomy tube and an external device to facilitate drainage of about 30% of the calories consumed in a meal, in conjunction with lifestyle (diet and exercise) counseling. METHODS: In this 52-week clinical trial, 207 participants with a body-mass index (BMI) of 35.0-55.0 kg/m(2) were randomly assigned in a 2:1 ratio to treatment with AspireAssist plus Lifestyle Counseling (n=137; mean BMI was 42...
December 6, 2016: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/27922025/water-exchange-method-significantly-improves-adenoma-detection-rate-a-multicenter-randomized-controlled-trial
#6
Hui Jia, Yanglin Pan, Xuegang Guo, Lina Zhao, Xiangping Wang, Linhui Zhang, Tao Dong, Hui Luo, Zhizheng Ge, Jun Liu, Jianyu Hao, Ping Yao, Yao Zhang, Hongyu Ren, Weizhen Zhou, Yujie Guo, Wei Zhang, Xiaolin Chen, Dayong Sun, Xiaoqiang Yang, Xiaoyu Kang, Na Liu, Zhiguo Liu, Felix Leung, Kaichun Wu, Daiming Fan
OBJECTIVES: Adenoma detection rate (ADR) is a key colonoscopy quality indicator in Western clinical literature. Our low ADR prompted us to assess novel methods to improve performance. Western retrospective reports suggested that water exchange (WE) could increase ADR. However, most of these studies used pain score or intubation rate as the primary outcome. Here we test the hypothesis that WE significantly increases ADR among Chinese colonoscopists and design a prospective randomized controlled trial using ADR as our primary outcome...
December 6, 2016: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/27922020/efficacy-of-losartan-in-the-management-of-post-dialysis-euvolemic-hypertension-held-trial-a-single-blind-randomized-control-trial
#7
Raja Ahsan Aftab, Amer Hayat Khan, Azreen Syazril Adnan, Syed Azhar Syed Sulaiman, Tahir Mehmood Khan
To assess the effectiveness of losartan 50 mg on post dialysis euvolemic hypertensive patients against standard antihypertensive pharmacotherapy. A multicentre, prospective, randomized, single-blind trial was conducted to assess the effect of losartan 50 mg every other day (EOD), once a morning (OM) among post-dialysis euvolemic hypertensive patients. Covariate-adaptive randomization was used to allocate participants to a standard or treatment arm, and they were followed up for eight weeks. Pre-, intra- and post-dialysis session blood pressure (BP) measurements were recorded along with any adverse events...
December 6, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27921577/the-efficiency-and-safety-of-trastuzumab-for-advanced-gastric-and-gastroesophageal-cancer-a-meta-analysis-of-five-randomized-controlled-trials
#8
Binghong Xiong, Li Ma, Wei Huang, Huayou Luo, Yujian Zeng, Yan Tian
A meta-analysis was performed to examine the efficiency and safety of trastuzumab in patients with advanced gastric and gastroesophageal cancer (AGC). By searching multiple databases from 1990 to March 2016, all randomized controlled trials (RCTs) which compared the effect of trastuzumab-combined chemotherapy (TC) versus chemotherapy alone (CT) in gastric cancer would be included. Five RCTs with a total of 875 patients were included. Trastuzumab can improve the overall survival (OS) rate, progression-free survival (PFS), one-year survival rate, two-year survival rate and overall response rate (ORR) of patients with AGC...
December 6, 2016: Growth Factors
https://www.readbyqxmd.com/read/27921445/risk-of-neonatal-and-childhood-morbidity-among-preterm-infants-exposed-to-marijuana
#9
Sarah K Dotters-Katz, Marcela C Smid, Tracy A Manuck, Torri D Metz
BACKGROUND: Limited data exist regarding the neonatal and neurodevelopmental outcomes of infants exposed to marijuana (MJ) in-utero, particularly among preterm infants. We hypothesized that MJ-exposed preterm infants would have worse neonatal and childhood developmental outcomes compared to MJ-unexposed infants. METHODS: Secondary analysis of multicenter randomized-controlled trial of antenatal magnesium sulfate for prevention of cerebral palsy was conducted. Singleton non-anomalous infants delivered <35 weeks exposed to MJ in-utero were compared to MJ-unexposed...
December 6, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27921414/the-effect-of-autologous-serum-therapy-on-disease-severity-in-patients-with-chronic-urticaria
#10
Farhad Abolnezhadian, Soheila Alyasin, Reza Amin, Maryam Babaei
Limited evidence has been obtained concerning the beneficial effects of autologous serum therapy in treatment of skin disorders particularly chronic urticaria. In the present study, we have assessed the effect of this treatment method in patients with chronic urticaria (CU). This randomized single-blind controlled trial was performed on fifty consecutive patients with chronic urticaria. The patients were randomly assigned to receive autologous serum (as the case group, n=35) or normal saline (as the control group, n=15) and treated with monthly autologous serum therapy or normal saline for 6 months...
August 2016: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/27921380/induction-of-labour-for-suspected-macrosomia-at-term-in-non-diabetic-women-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#11
REVIEW
E R Magro-Malosso, G Saccone, M Chen, R Navathe, M Di Tommaso, V Berghella
BACKGROUND: Several randomized controlled trials (RCTs) compared induction of labour with expectant management in non-diabetic women with suspected fetal macrosomia. OBJECTIVE: To evaluate the effects of labour induction for suspected fetal macrosomia. SEARCH STRATEGY: Literature search in electronic databases. SELECTION CRITERIA: We included all RCTs of suspected fetal macrosomia comparing labour induction with expectant management in term pregnancy...
December 5, 2016: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27921257/impact-of-community-health-workers-on-use-of-healthcare-services-in-the-united-states-a-systematic-review
#12
Helen E Jack, Sophia D Arabadjis, Lucy Sun, Erin E Sullivan, Russell S Phillips
BACKGROUND: As the US transitions to value-based healthcare, physicians and payers are incentivized to change healthcare delivery to improve quality of care while controlling costs. By assisting with the management of common chronic conditions, community health workers (CHWs) may improve healthcare quality, but physicians and payers who are making choices about care delivery also need to understand their effects on healthcare spending. METHODS: We searched PubMed, Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, PsycINFO, Embase, and Web of Science from the inception of each database to 22 June 2015...
December 5, 2016: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/27921252/opioid-induced-bowel-dysfunction-in-patients-undergoing-spine-surgery-comparison-of-oxycodone-and-oxycodone-naloxone-treatment
#13
Merja Kokki, Moona Kuronen, Toivo Naaranlahti, Timo Nyyssönen, Ira Pikkarainen, Sakari Savolainen, Hannu Kokki
INTRODUCTION: Opioids are needed for postoperative pain in spine surgery patients, but opioid-induced constipation is a harmful adverse event. The aim of this clinical trial was to compare the use of a controlled-release oxycodone-naloxone combination product with oxycodone controlled-release tablets in these patients. The main outcome measure was the prevalence of constipation at 7 days postoperatively assessed with a Bowel Function Index questionnaire. A follow-up assessment at 21 days after surgery was also included...
December 5, 2016: Advances in Therapy
https://www.readbyqxmd.com/read/27921196/danshen-injection-as-adjuvant-treatment-for-unstable-angina-pectoris-a-systematic-review-and-meta-analysis
#14
Jia-Rui Wu, Shi Liu, Xiao-Meng Zhang, Bing Zhang
OBJECTIVE: To systematically evaluate the clinical effectiveness and safety of Danshen Injection (, DS) as one adjuvant treatment for conventional therapy with Western medicine (WM) for unstable angina pectoris (UAP). METHODS: Using literature databases, a thorough and systematic retrieval of randomized controlled trials (RCTs) comparing DS plus WM with WM was conducted from inception to April 2015. The extracted data from included studies was analyzed by Review Manager 5...
December 5, 2016: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/27921162/multicentre-randomized-trial-of-the-ajust%C3%A2-single-incision-sling-compared-to-the-align%C3%A2-transobturator-tape-sling
#15
Jordi Sabadell, Marta Palau-Gené, Eva Huguet, Anabel Montero-Armengol, Sabina Salicrú, Jose L Poza
INTRODUCTION AND HYPOTHESIS: Tension-free suburethral tapes have become the first-line surgical treatment for female stress urinary incontinence. Single-incision midurethral slings (SIMS) were introduced with the aim of offering similar efficacy with reduced morbidity, particularly postoperative pain. The objective of this study was to compare the effectiveness and complications of the Ajust™ SIMS and the Align™ transobturator tape sling. METHODS: We performed a randomized controlled trial with a noninferiority design...
December 5, 2016: International Urogynecology Journal
https://www.readbyqxmd.com/read/27921090/the-effect-of-intrauterine-human-chorionic-gonadotropin-injection-before-embryo-transfer-on-the-implantation-and-pregnancy-rate-in-infertile-patients-a-randomized-clinical-trial
#16
Razieh Dehghani Firouzabadi, Sima Janati, Mohammad Hossein Razi
BACKGROUND: Implantation is one of the essential steps for the success of assisted reproductive techniques (ART). Their success depends on three main factors: embryo quality, endometrial receptivity (ER), and synchrony between embryo and endometrium. There are various factors that regulate the complex process of implantation. In this regard, one may refer to human chorionic gonadotropin (hCG) as the most important factor. OBJECTIVE: This study aims to investigate the effect of intrauterine hCG injection before embryo transfer (ET) on pregnancy outcome in infertile couples...
October 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/27921088/intra-uterine-extra-amniotic-versus-vaginal-misoprostol-for-termination-of-second-trimester-miscarriage-a-randomized-controlled-trial
#17
Abo Bakr Abbas Mitwaly, Ahmed Mohamed Abbas, Mohamed Sayed Abdellah
BACKGROUND: Termination of pregnancy in the second trimester using prostaglandins has been shown to be safe and effective. Misoprostol has multiple routes of administration; oral, vaginal, buccal, rectal and sublingual. OBJECTIVE: The study aims to compare the efficacy and safety of intrauterine extra-amniotic and vaginal misoprostol in a dose of 200 microgram every 4 hours for the termination of pregnancy in cases of second trimester miscarriage. MATERIALS AND METHODS: A prospective randomized open labeled clinical trial included 180 women with missed miscarriage in gestational age between 13 and 24 wks...
October 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/27920590/a-comparison-of-the-oxford-shoulder-score-and-shoulder-pain-and-disability-index-factor-structure-in-the-context-of-a-large-randomized-controlled-trial
#18
Jill Dawson, Kristina K Harris, Helen Doll, Ray Fitzpatrick, Andrew Carr
BACKGROUND: To explore and compare the factor structure of the 12-item Oxford shoulder score (OSS) and 13-item shoulder pain and disability index (SPADI). METHODS: Exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) of data from 660 patients attending 46 hospitals in the UK. Complete OSS and SPADI data were available for 648 (98.2%) and 628 (95.2%) participants, respectively. RESULTS: For both instruments, either one or two factors were indicated, depending on the extraction method...
2016: Patient related Outcome Measures
https://www.readbyqxmd.com/read/27920564/prioritizing-health-system-and-disease-burden-factors-an-evaluation-of-the-net-benefit-of-transferring-health-technology-interventions-to-different-districts-in-zimbabwe
#19
Shepherd Shamu, Simbarashe Rusakaniko, Charles Hongoro
INTRODUCTION: Health-care technologies (HCTs) play an important role in any country's health-care system. Zimbabwe's health-care system uses a lot of HCTs developed in other countries. However, a number of local factors have affected the absorption and use of these technologies. We therefore set out to test the hypothesis that the net benefit regression framework (NBRF) could be a helpful benefit testing model that enables assessment of intra-national variables in HCT transfer. METHOD: We used an NBRF model to assess the benefits of transferring cost-effective technologies to different jurisdictions...
2016: ClinicoEconomics and Outcomes Research: CEOR
https://www.readbyqxmd.com/read/27920542/protective-effect-of-tartary-buckwheat-on-renal-function-in-type-2-diabetics-a-randomized-controlled-trial
#20
Ju Qiu, Zaigui Li, Yuchang Qin, Yanfen Yue, Yanping Liu
Tartary buckwheat (TB) has been reported to be associated with a decreased risk of type 2 diabetes mellitus (T2DM), and T2DM has had a major impact on the development of diabetic kidney disease (DKD). Thus, the hypothesis that a daily intake of TB will improve DKD risk factors, including urinary albumin to creatinine ratio (UACR), urea nitrogen (UN), serum creatinine, and uric acid was tested. In a parallel, randomized, open-label controlled trial, 104 T2DM patients were randomly assigned to a diet control group (systematic diet plans and intensive nutritional education) or a TB intervention group (daily replacement of a portion of staple foods with TB foods)...
2016: Therapeutics and Clinical Risk Management
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