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https://www.readbyqxmd.com/read/29075849/decreased-lipogenesis-promoting-factors-in-adipose-tissue-in-postmenopausal-women-with-overweight-on-a-paleolithic-type-diet
#1
Caroline Blomquist, Elin Chorell, Mats Ryberg, Caroline Mellberg, Evelina Worrsjö, Elena Makoveichuk, Christel Larsson, Bernt Lindahl, Gunilla Olivecrona, Tommy Olsson
PURPOSE: We studied effects of diet-induced postmenopausal weight loss on gene expression and activity of proteins involved in lipogenesis and lipolysis in adipose tissue. METHODS: Fifty-eight postmenopausal women with overweight (BMI 32.5 ± 5.5) were randomized to eat an ad libitum Paleolithic-type diet (PD) aiming for a high intake of protein and unsaturated fatty acids or a prudent control diet (CD) for 24 months. Anthropometry, plasma adipokines, gene expression of proteins involved in fat metabolism in subcutaneous adipose tissue (SAT) and lipoprotein lipase (LPL) activity and mass in SAT were measured at baseline and after 6 months...
October 26, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/29038900/correction-to-dietary-interventions-and-multiple-sclerosis
#2
Ghadah Altowaijri, Allison Fryman, Vijayshree Yadav
The original version of this article contains an error in the second sentence of the second paragraph of the Paleolithic Diet section.
October 17, 2017: Current Neurology and Neuroscience Reports
https://www.readbyqxmd.com/read/28901333/a-paleolithic-type-diet-results-in-iodine-deficiency-a-2-year-randomized-trial-in-postmenopausal-obese-women
#3
S Manousou, M Stål, C Larsson, C Mellberg, B Lindahl, R Eggertsen, L Hulthén, T Olsson, M Ryberg, S Sandberg, H F Nyström
BACKGROUND/OBJECTIVES: Different diets are used for weight loss. A Paleolithic-type diet (PD) has beneficial metabolic effects, but two of the largest iodine sources, table salt and dairy products, are excluded. The objectives of this study were to compare 24-h urinary iodine concentration (24-UIC) in subjects on PD with 24-UIC in subjects on a diet according to the Nordic Nutrition Recommendations (NNR) and to study if PD results in a higher risk of developing iodine deficiency (ID), than NNR diet...
September 13, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28758964/effects-of-popular-diets-without-specific-calorie-targets-on-weight-loss-outcomes-systematic-review-of-findings-from-clinical-trials
#4
Stephen D Anton, Azumi Hida, Kacey Heekin, Kristen Sowalsky, Christy Karabetian, Heather Mutchie, Christiaan Leeuwenburgh, Todd M Manini, Tracey E Barnett
The present review examined the evidence base for current popular diets, as listed in the 2016 U.S. News & World Report, on short-term (≤six months) and long-term (≥one year) weight loss outcomes in overweight and obese adults. For the present review, all diets in the 2016 U.S. News & World Report Rankings for "Best Weight-Loss Diets", which did not involve specific calorie targets, meal replacements, supplementation with commercial products, and/or were not categorized as "low-calorie" diets were examined...
July 31, 2017: Nutrients
https://www.readbyqxmd.com/read/28605019/the-late-neandertal-permanent-lower-left-third-premolar-from-walou-cave-trooz-belgium-and-its-context
#5
Michel Toussaint, Christine Verna, Adeline Le Cabec, Aida Gómez-Robles, Christelle Draily, Michael P Richards, Stéphane Pirson
OBJECTIVES: We describe a hominin permanent lower left third premolar unearthed in 1997 at Walou Cave (Belgium), found in direct association with a Mousterian lithic industry, in a layer directly dated to 40-38,000 years BP. MATERIALS AND METHODS: The taxonomical attribution of the tooth is addressed through comparative morphometric analyses, and stable isotope analyses aimed at determining the diet of the individual. RESULTS: The Walou P3 plots within the Neandertal range of variation and is significantly different from recent modern humans in all morphometric assessments...
September 2017: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/28526915/dietary-behaviors-in-psoriasis-patient-reported-outcomes-from-a-u-s-national-survey
#6
Ladan Afifi, Melissa J Danesh, Kristina M Lee, Kevin Beroukhim, Benjamin Farahnik, Richard S Ahn, Di Yan, Rasnik K Singh, Mio Nakamura, John Koo, Wilson Liao
INTRODUCTION: Psoriasis patients demonstrate high interest in the role of diet on their skin condition. However, data are lacking to describe dietary interventions among psoriasis patients and associated outcomes. This study aims to identify common dietary habits, interventions and perceptions among patients with psoriasis, and to examine patient-reported skin outcomes in response to these interventions. METHODS: We administered a 61-question survey to the National Psoriasis Foundation membership asking psoriasis patients about dietary habits, modifications, skin responses, and perceptions...
June 2017: Dermatology and Therapy
https://www.readbyqxmd.com/read/28440046/attenuated-low-grade-inflammation-following-long-term-dietary-intervention-in-postmenopausal-women-with-obesity
#7
Caroline Blomquist, Malin Alvehus, Jonas Burén, Mats Ryberg, Christel Larsson, Bernt Lindahl, Caroline Mellberg, Ingegerd Söderström, Elin Chorell, Tommy Olsson
OBJECTIVE: Abdominal fat accumulation after menopause is associated with low-grade inflammation and increased risk of metabolic disorders. Effective long-term lifestyle treatment is therefore needed. METHODS: Seventy healthy postmenopausal women (age 60 ± 5.6 years) with BMI 32.5 ± 5.5 were randomized to a Paleolithic-type diet (PD) or a prudent control diet (CD) for 24 months. Blood samples and fat biopsies were collected at baseline, 6 months, and 24 months to analyze inflammation-related parameters...
May 2017: Obesity
https://www.readbyqxmd.com/read/28394724/a-multimodal-nonpharmacologic-intervention-improves-mood-and-cognitive-function-in-people-with-multiple-sclerosis
#8
Jennifer E Lee, Babita Bisht, Michael J Hall, Linda M Rubenstein, Rebecca Louison, Danielle T Klein, Terry L Wahls
OBJECTIVE: The objective of this study was to examine whether participation in a 12-month multimodal intervention would improve mood and cognitive function in adults with progressive multiple sclerosis (MS). METHODS: In this one-arm, open-label feasibility trial, participants were prescribed a home-based multimodal intervention, including (1) a modified Paleolithic diet; (2) an exercise program (stretching and strengthening of the trunk and lower limb muscles); (3) neuromuscular electrical stimulation (EStim) of trunk and lower limb muscles; and (4) stress management (meditation and self-massage)...
March 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/28179490/paleolithic-and-mediterranean-diet-pattern-scores-are-inversely-associated-with-all-cause-and-cause-specific-mortality-in-adults
#9
Kristine A Whalen, Suzanne Judd, Marjorie L McCullough, W Dana Flanders, Terryl J Hartman, Roberd M Bostick
Background: Poor diet quality is associated with a higher risk of many chronic diseases that are among the leading causes of death in the United States. It has been hypothesized that evolutionary discordance may account for some of the higher incidence and mortality from these diseases.Objective: We investigated associations of 2 diet pattern scores, the Paleolithic and the Mediterranean, with all-cause and cause-specific mortality in the REGARDS (REasons for Geographic and Racial Differences in Stroke) study, a longitudinal cohort of black and white men and women ≥45 y of age...
April 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28034447/c282y-h63d-hemochromatosis-mutations-and-microevolution-speculations-concerning-the-basque-population
#10
F Bauduer
The Basques live at the Western extremity of the Pyrenees. According to linguistic and genetic data they could be considered as one of the most ancient European populations. Numerous studies have evidenced particular patterns in the frequency of several genetic polymorphisms in this relatively unmixed human group. We discuss herein the puzzling distribution of the two major hemochromatosis HFE mutations associated with hereditary hemochromatosis. Thus, one can observe a low frequency of C282Y and, in contrast, one of the highest European frequencies of H63D...
January 2017: Homo: Internationale Zeitschrift Für die Vergleichende Forschung Am Menschen
https://www.readbyqxmd.com/read/27930293/the-plant-component-of-an-acheulian-diet-at-gesher-benot-ya-aqov-israel
#11
Yoel Melamed, Mordechai E Kislev, Eli Geffen, Simcha Lev-Yadun, Naama Goren-Inbar
Diet is central for understanding hominin evolution, adaptation, and environmental exploitation, but Paleolithic plant remains are scarce. A unique macrobotanical assemblage of 55 food plant taxa from the Acheulian site of Gesher Benot Ya'aqov, Israel includes seeds, fruits, nuts, vegetables, and plants producing underground storage organs. The food plant remains were part of a diet that also included aquatic and terrestrial fauna. This diverse assemblage, 780,000 y old, reflects a varied plant diet, staple plant foods, environmental knowledge, seasonality, and the use of fire in food processing...
December 20, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27851309/1674-ketoacidosis-in-a-breast-feeding-patient-on-the-paleolithic-diet
#12
Evan Diamond, Samarth Beri, Erik Perez, Fawzi Ameer
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27753214/how-to-make-stone-soup-is-the-paleo-diet-a-missed-opportunity-for-anthropologists
#13
Melanie L Chang, April Nowell
For the past few years, people everywhere have been "going Paleo." Websites and social media touting the benefits of eating a "Paleo diet" and following a "Paleolithic life style" serve as calls to arms for health-conscious individuals seeking information about the latest health and fitness trends. Many of these people participate in programs such as Crossfit, which involve major social and life-style modification components and therefore facilitate the dissemination of dietary fads.(1) The PALEOf(x)(TM) conference, which bills itself as "the world's premier holistic wellness event," has attracted sellout crowds of thousands of attendees for the last four years...
September 2016: Evolutionary Anthropology
https://www.readbyqxmd.com/read/27692243/the-relation-of-saturated-fatty-acids-with-low-grade-inflammation-and-cardiovascular-disease
#14
REVIEW
Begoña Ruiz-Núñez, D A Janneke Dijck-Brouwer, Frits A J Muskiet
The mantra that dietary (saturated) fat must be minimized to reduce cardiovascular disease (CVD) risk has dominated nutritional guidelines for decades. Parallel to decreasing intakes of fat and saturated fatty acids (SFA), there have been increases in carbohydrate and sugar intakes, overweight, obesity and type 2 diabetes mellitus. The "lipid hypothesis" coined the concept that fat, especially SFA, raises blood low-density lipoprotein-cholesterol and thereby CVD risk. In view of current controversies regarding their adequate intakes and effects, this review aims to summarize research regarding this heterogenic group of fatty acids and the mechanisms relating them to (chronic) systemic low-grade inflammation, insulin resistance, metabolic syndrome and notably CVD...
October 2016: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/27666153/can-the-paleolithic-diet-meet-the-nutritional-needs-of-older-people
#15
EDITORIAL
Richard Hoffman
No abstract text is available yet for this article.
January 2017: Maturitas
https://www.readbyqxmd.com/read/27509519/compliance-palatability-and-feasibility-of-paleolithic-and-australian-guide-to-healthy-eating-diets-in-healthy-women-a-4-week-dietary-intervention
#16
RANDOMIZED CONTROLLED TRIAL
Angela Genoni, Johnny Lo, Philippa Lyons-Wall, Amanda Devine
(1) BACKGROUND/OBJECTIVES: The Paleolithic diet has been receiving media coverage in Australia and claims to improve overall health. The diet removes grains and dairy, whilst encouraging consumption of fruits, vegetables, meat, eggs and nuts. Our aim was to compare the diet to the Australian Guide to Healthy Eating (AGHE) in terms of compliance, palatability and feasibility; (2) SUBJECTS/METHODS: 39 healthy women (age 47 ± 13 years, BMI 27 ± 4 kg/m²) were randomised to an ad-libitum Paleolithic (n = 22) or AGHE diet (n = 17) for 4-weeks...
August 6, 2016: Nutrients
https://www.readbyqxmd.com/read/27412573/dietary-patterns-and-risk-of-colorectal-adenoma-a-systematic-review-and-meta-analysis-of-observational-studies
#17
J Godos, F Bella, A Torrisi, S Sciacca, F Galvano, G Grosso
BACKGROUND: Current evidence suggests that dietary patterns may play an important role in colorectal cancer risk. The present study aimed to perform a systematic review and meta-analysis of observational studies exploring the association between dietary patterns and colorectal adenomas (a precancerous condition). METHODS: Pubmed and EMBASE electronic databases were systematically searched to retrieve eligible studies. Only studies exploring the risk or association with colorectal adenomas for the highest versus lowest category of exposure to a posteriori dietary patterns were included in the quantitative analysis...
December 2016: Journal of Human Nutrition and Dietetics: the Official Journal of the British Dietetic Association
https://www.readbyqxmd.com/read/27355913/role-of-diet-in-inflammatory-bowel-disease
#18
Frank M Ruemmele
The incidence of inflammatory bowel disease (IBD) is steadily in the rise in Western as well as in developing countries paralleling the increase of westernized diets, characterized by high protein and fat as well as excessive sugar intake, with less vegetables and fiber. An interesting hypothesis is that environmental (food-) triggered changes of the intestinal microbiome might cause a proinflammatory state preceding the development of IBD. Indeed, an intact intestinal epithelial barrier assuring a normal bacterial clearance of the intestinal surface is crucial to guarantee intestinal homeostasis...
2016: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/27235022/benefits-of-a-paleolithic-diet-with-and-without-supervised-exercise-on-fat-mass-insulin-sensitivity-and-glycemic-control-a-randomized-controlled-trial-in-individuals-with-type-2-diabetes
#19
RANDOMIZED CONTROLLED TRIAL
Julia Otten, Andreas Stomby, Maria Waling, Andreas Isaksson, Anna Tellström, Lillemor Lundin-Olsson, Søren Brage, Mats Ryberg, Michael Svensson, Tommy Olsson
BACKGROUND: Means to reduce future risk for cardiovascular disease in subjects with type 2 diabetes are urgently needed. METHODS: Thirty-two patients with type 2 diabetes (age 59 ± 8 years) followed a Paleolithic diet for 12 weeks. Participants were randomized to either standard care exercise recommendations (PD) or 1-h supervised exercise sessions (aerobic exercise and resistance training) three times per week (PD-EX). RESULTS: For the within group analyses, fat mass decreased by 5...
January 2017: Diabetes/metabolism Research and Reviews
https://www.readbyqxmd.com/read/27223304/cardiovascular-metabolic-effects-and-dietary-composition-of-ad-libitum-paleolithic-vs-australian-guide-to-healthy-eating-diets-a-4-week-randomised-trial
#20
RANDOMIZED CONTROLLED TRIAL
Angela Genoni, Philippa Lyons-Wall, Johnny Lo, Amanda Devine
(1) BACKGROUND: The Paleolithic diet is popular in Australia, however, limited literature surrounds the dietary pattern. Our primary aim was to compare the Paleolithic diet with the Australian Guide to Healthy Eating (AGHE) in terms of anthropometric, metabolic and cardiovascular risk factors, with a secondary aim to examine the macro and micronutrient composition of both dietary patterns; (2) METHODS: 39 healthy women (mean ± SD age 47 ± 13 years, BMI 27 ± 4 kg/m²) were randomised to either the Paleolithic (n = 22) or AGHE diet (n = 17) for four weeks...
May 23, 2016: Nutrients
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