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https://www.readbyqxmd.com/read/27933541/social-interactions-and-indirect-genetic-effects-on-complex-juvenile-and-adult-traits
#1
David G Ashbrook, Reinmar Hager
Most animal species are social in one form or another, yet many studies in rodent model systems use either individually housed animals or ignore potential confounds caused by group housing. While such social interaction effects on developmental and behavioral traits are well established, the genetic basis of social interactions has not been researched in as much detail. Specifically, the effects of genetic variation in social partners on the phenotype of a focal individual have mostly been studied at the phenotypic level...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/27933427/minimal-impact-of-response-shift-for-sf-12-mental-and-physical-health-status-in-homeless-and-vulnerably-housed-individuals-an-item-level-multi-group-analysis
#2
Anne M Gadermann, Richard Sawatzky, Anita Palepu, Anita M Hubley, Bruno D Zumbo, Tim Aubry, Susan Farrell, Stephen W Hwang
PURPOSE: The purpose of this study was to examine whether homeless or vulnerably housed individuals experienced response shift over a 12-month time period in their self-reported physical and mental health status. METHODS: Data were obtained from the Health and Housing in Transition study, a longitudinal multi-site cohort study in Canada (N = 1190 at baseline). Multi-group confirmatory factor analysis (MG-CFA) and methods for response shift detection at the item level, based on the approach by Oort, were used to test for reconceptualization, reprioritization, and recalibration response shift on the SF-12 in four groups of individuals who were homeless (n = 170), housed (n = 437), or who reported a change in their housing status [from homeless to housed (n = 285) or housed to homeless (n = 73)] over a 12-month time period...
December 8, 2016: Quality of Life Research
https://www.readbyqxmd.com/read/27933288/health-complaints-associated-with-poor-rental-housing-conditions-in-arkansas-the-only-state-without-a-landlord-s-implied-warranty-of-habitability
#3
Ashley E Bachelder, M Kate Stewart, Holly C Felix, Neil Sealy
Arkansas is the only U.S. state that does not have a landlord's implied warranty of habitability, meaning tenants have a requirement for maintaining their rental properties at certain habitability standards, but landlords are not legally required to contribute to those minimum health and safety standards. This project assessed the possibility that this lack of landlord responsibility affects tenants' perceived health. Using surveys and interviews, we collected self-reported data on the prevalence and description of problems faced by renters who needed household repairs from their landlords...
2016: Frontiers in Public Health
https://www.readbyqxmd.com/read/27933150/implementing-mobile-devices-to-reduce-non-rostered-workload-for-junior-doctors
#4
Allan Plant, Suzanne Round, Joe Bourne
There is a large body of evidence demonstrating the detrimental effect of long work hours on the performance, mood, and job satisfaction of junior doctors. By extension these effects carry over into the realm of patient safety, compromising the quality of care provision. House officers in the general surgery department of Tauranga Hospital, New Zealand are often required to arrive at work well before their rostered start time of 7.30am to hand write the results of clinical investigations on their patient lists...
2016: BMJ Quality Improvement Reports
https://www.readbyqxmd.com/read/27932832/should-implants-be-considered-for-patients-with-periodontal-disease
#5
E King, R Patel, A Patel, L Addy
Dental implants are seen as a good option for replacing missing teeth. The success and survival rates for implants are very high. Concerns are developing about the problem of peri-implantitis. The reports of its prevalence vary but it is noted that the presence of periodontal disease is a risk factor. The issue of peri-implantitis was raised in the House of Lords in 2014. Complaints relating to implants is on the rise with the General Dental Council. Placement of implants in patients with periodontal disease is not a treatment that should be done without a full periodontal assessment and stabilisation of periodontal disease first...
December 9, 2016: British Dental Journal
https://www.readbyqxmd.com/read/27932683/survival-of-bacteria-of-laboratory-animal-origin-on-cage-bedding-and-inactivation-by-hydrogen-peroxide-vapour
#6
Laurentiu Benga, W Peter M Benten, Eva Engelhardt, Christina Gougoula, Roland Schulze-Röbbecke, Martin Sager
This study aims to determine the ability of laboratory animal bacteria to resist desiccation and inactivation by hydrogen peroxide vapour (HPV) on paper bedding pieces. Bedding pieces were saturated with bacterial suspensions in water or 2% (w/v) bovine serum albumin (BSA) in water, and held in a mouse facility. Viable counts showed variable survival rates over time for the bacterial species used ([Pasteurella] pneumotropica, Muribacter muris, Pseudomonas aeruginosa, Acinetobacter redioresistens, Escherichia coli, Klebsiella oxytoca, Bordetella bronchiseptica, Bordetella hinzii, Enterococcus faecalis, β-haemolytic Streptococcus spp...
December 8, 2016: Laboratory Animals
https://www.readbyqxmd.com/read/27931888/community-treatment-orders-a-pause-for-thought
#7
Maninder Kaur Nagra, Toby Pillinger, Henrique Prata-Ribeiro, Yasser Khazaal, Andrew Molodynski
Community Treatment Orders (CTO) have been available for several decades in some countries and are being progressively introduced worldwide, with significant uptake in Asian countries as they move more mental health care into the community. However the evidence for the effectiveness of CTOs is limited. The evidence from local audits and evaluations is conflicted with some studies showing clear benefit and others not. The same is the case for uncontrolled before and after studies. The higher levels of evidence such as randomised controlled trials, systematic reviews, and Cochrane reviews have consistently failed to demonstrate benefits from CTO use on key measures such as symptom levels, functioning, and healthcare use...
December 2016: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/27931317/influence-of-rack-design-and-disease-prevalence-on-detection-of-rodent-pathogens-in-exhaust-debris-samples-from-individually-ventilated-caging-systems
#8
Beth A Bauer, Cynthia Besch-Williford, Robert S Livingston, Marcus J Crim, Lela K Riley, Matthew H Myles
Sampling of bedding debris within the exhaust systems of ventilated racks may be a mechanism for detecting murine pathogens in colony animals. This study examined the effectiveness of detecting pathogens by PCR analysis of exhaust debris samples collected from ventilated racks of 2 different rack designs, one with unfiltered air flow from within the cage to the air-exhaust pathway, and the other had a filter between the cage and the air-exhaust pathway. For 12 wk, racks were populated with either 1 or 5 cages of mice (3 mice per cage) infected with one of the following pathogens: mouse norovirus (MNV), mouse parvovirus (MPV), mouse hepatitis virus (MHV), Helicobacter spp...
November 2016: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/27931316/exhaust-air-dust-monitoring-is-superior-to-soiled-bedding-sentinels-for-the-detection-of-pasteurella-pneumotropica-in-individually-ventilated-cage-systems
#9
Manuel Miller, Brbel Ritter, Julia Zorn, Markus Brielmeier
Reliable detection of unwanted organisms is essential for meaningful health monitoring in experimental animal facilities. Currently, most rodents are housed in IVC systems, which prevent the aerogenic transmission of pathogens between cages. Typically soiled-bedding sentinels (SBS) exposed to soiled bedding collected from a population of animals within an IVC rack are tested as representatives, but infectious agents often go undetected due to inefficient transmission. Pasteurellaceae are among the most prevalent bacterial pathogens isolated from experimental mice, and the failure of SBS to detect these bacteria is well established...
November 2016: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/27931313/behavioral-effects-of-an-enhanced-enrichment-program-for-group-housed-sooty-mangabeys-cercocebus-atys
#10
Jessica Crast, Mollie A Bloomsmith, Trina J Jonesteller
Evaluating the behavioral effects of enrichment on animals housed in biomedical facilities is necessary to effectively support their care and wellbeing. We tested the cumulative effects of an enhanced enrichment program on sooty mangabey behavior: locomotion, feeding and foraging, manipulating items in the enclosure, social affiliation, aggression, and abnormal behavior. The enhanced enrichment program included the addition of a substrate (timothy hay), widely distributing small pieces of produce and a forage mixture in the hay, adding structures and perching, and increasing the variety of food items, foraging devices, and other manipulable items...
November 2016: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/27931309/the-social-nature-of-european-rabbits-oryctolagus-cuniculus
#11
Louis DiVincenti, Angelika N Rehrig
Increasing concerns regarding the wellbeing of laboratory animals have caused biomedical research stakeholders to reconsider traditional housing of laboratory species and to provide social companionship for social species. European rabbits (Oryctolagus cuniculus) are commonly individually housed in research facilities despite the occurrence of social groups in the wild. Here we review the current literature to provide a comprehensive description of the social behaviors and preferences of rabbits in the wild and in captivity...
November 2016: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/27931234/patterns-and-determinants-of-malaria-risk-in-urban-and-peri-urban-areas-of-blantyre-malawi
#12
Don P Mathanga, Atupele Kapito Tembo, Themba Mzilahowa, Andy Bauleni, Kondwani Mtimaukenena, Terrie E Taylor, Clarissa Valim, Edward D Walker, Mark L Wilson
BACKGROUND: Although malaria disease in urban and peri-urban areas of sub-Saharan Africa is a growing concern, the epidemiologic patterns and drivers of transmission in these settings remain poorly understood. Factors associated with variation in malaria risk in urban and peri-urban areas were evaluated in this study. METHODS: A health facility-based, age and location-matched, case-control study of children 6-59 months of age was conducted in four urban and two peri-urban health facilities (HF) of Blantyre city, Malawi...
December 8, 2016: Malaria Journal
https://www.readbyqxmd.com/read/27931146/d-cycloserine-restores-experience-dependent-neuroplasticity-after-tbi-in-the-developing-rat-brain
#13
Naomi Sulit Sta Maria, Maxine Lane Reger, Yan Cai, Mary Anne Tezheart Mercado Baquing, Floyd Buen, Aditya Ponnaluri, David Hovda, Neil G Harris, Christopher C Giza
Traumatic brain injury (TBI) in children can cause persisting cognitive and behavioral dysfunction and inevitably raises concerns about lost potential in these injured youths. Lateral fluid percussion injury (FPI) in weanling rats pathologically affects hippocampal NMDAR- and AMPAR-mediated glutamatergic neurotransmission subacutely, within the first post-injury week. FPI to weanling rats has also been shown to impair enriched-environment (EE) induced enhancement of Morris water maze (MWM) learning and memory in adulthood...
December 8, 2016: Journal of Neurotrauma
https://www.readbyqxmd.com/read/27931004/increasing-trend-of-wearables-and-multimodal-interface-for-human-activity-monitoring-a-review
#14
REVIEW
Preeti Kumari, Lini Mathew, Poonal Syal
Activity recognition technology is one of the most important technologies for life-logging and for the care of elderly persons. Elderly people prefer to live in their own houses, within their own locality. If, they are capable to do so, several benefits can follow in terms of society and economy. However, living alone may have high risks. Wearable sensors have been developed to overcome these risks and these sensors are supposed to be ready for medical uses. It can help in monitoring the wellness of elderly persons living alone by unobtrusively monitoring their daily activities...
December 2, 2016: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/27930936/sunlight-exposure-increases-vitamin-d-sufficiency-in-growing-pigs-fed-a-diet-formulated-to-exceed-requirements
#15
B M Alexander, B C Ingold, J L Young, S R Fensterseifer, P J Wechsler, K J Austin, D E Larson-Meyer
Traditional confinement practices limit exposure to sunlight and vitamin D synthesis, and vitamin insufficiency occurs even with dietary supplementation. The aim of this study was to determine the effect of limited sun exposure on serum concentration of vitamin D and the expression of vitamin D synthesizing enzymes in the liver and kidney of pigs on a vitamin D sufficient diet. White-pigmented grower pigs (29.7 ± 2.3 kg) fed 15% CP diet ad libitum providing >1,200 IU vitamin D3/kg of feed were exposed to sunlight for 1 h each day at solar noon for 14 d at the spring equinox (March pigs, n = 10) or summer solstice (June pigs, n = 5) and again before slaughter in June (March pigs) and September (June pigs)...
November 11, 2016: Domestic Animal Endocrinology
https://www.readbyqxmd.com/read/27930807/exploring-flybase-data-using-quicksearch
#16
Steven J Marygold, Giulia Antonazzo, Helen Attrill, Marta Costa, Madeline A Crosby, Gilberto Dos Santos, Joshua L Goodman, L Sian Gramates, Beverley B Matthews, Alix J Rey, Jim Thurmond
FlyBase (flybase.org) is the primary online database of genetic, genomic, and functional information about Drosophila species, with a major focus on the model organism Drosophila melanogaster. The long and rich history of Drosophila research, combined with recent surges in genomic-scale and high-throughput technologies, mean that FlyBase now houses a huge quantity of data. Researchers need to be able to rapidly and intuitively query these data, and the QuickSearch tool has been designed to meet these needs...
December 8, 2016: Current Protocols in Bioinformatics
https://www.readbyqxmd.com/read/27930763/association-among-facial-paralysis-depression-and-quality-of-life-in-facial-plastic-surgery-patients
#17
Jason C Nellis, Masaru Ishii, Patrick J Byrne, Kofi D O Boahene, Jacob K Dey, Lisa E Ishii
Importance: Though anecdotally linked, few studies have investigated the impact of facial paralysis on depression and quality of life (QOL). Objective: To measure the association between depression, QOL, and facial paralysis in patients seeking treatment at a facial plastic surgery clinic. Design, Setting, Participants: Data were prospectively collected for patients with all-cause facial paralysis and control patients initially presenting to a facial plastic surgery clinic from 2013 to 2015...
December 8, 2016: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/27930734/pathogenic-mutations-in-cancer-predisposing-genes-a-survey-of-300-patients-with-whole-genome-sequencing-and-lifetime-electronic-health-records
#18
Karen Y He, Yiqing Zhao, Elizabeth W McPherson, Quan Li, Fan Xia, Chunhua Weng, Kai Wang, Max M He
BACKGROUND: It is unclear whether and how whole-genome sequencing (WGS) data can be used to implement genomic medicine. Our objective is to retrospectively evaluate whether WGS can facilitate improving prevention and care for patients with susceptibility to cancer syndromes. METHODS AND FINDINGS: We analyzed genetic mutations in 60 autosomal dominant cancer-predisposition genes in 300 deceased patients with WGS data and nearly complete long-term (over 30 years) medical records...
2016: PloS One
https://www.readbyqxmd.com/read/27930726/burnout-and-its-influencing-factors-among-primary-health-care-providers-in-the-north-east-of-iran
#19
Mohammad Amiri, Ahmad Khosravi, Ahmad Reza Eghtesadi, Zakieh Sadeghi, Ghasem Abedi, Mansour Ranjbar, Fardin Mehrabian
INTRODUCTION: Burnout is a popular research topics in service providing jobs, including the health care field. This study aimed at assessing the level of job burnout and to consider the important antecedents which might be related to job burnout among primary health care providers in Iran. METHODS: The participants in this applied cross-sectional study which was conducted in 2013 were 548 primary health care providers who were randomly selected from among those working in Shahroud, Sabzevar, Neishabour, Bojnord (provinces located in the north east of Iran)...
2016: PloS One
https://www.readbyqxmd.com/read/27930512/religious-stigmata-as-malingering-artifact-report-of-a-case-and-review-of-the-literature
#20
Domenico Bonamonte, Michelangelo Vestita, Angela Filoni, Giuseppe Giudice, Gianni Angelini
RATIONALE: Artifacts or simulated diseases are self-inflicted conditions caused by various means and for different purposes. Disease simulation can be motivated, among other things, by illegal purposes, to escape from civil duties or prison sentences, for example, or to exploit specific situations in order to receive a range of benefits. In such cases, the simulator is fully aware of his or her actions and intentions. DIAGNOSES, INTERVENTIONS AND OUTCOMES: We report the case of a 42-year-old woman who, for 3 consecutive years, showed religious stigmata on the forehead and on the dorsal surface of hands and feet immediately before Easter...
December 2016: Medicine (Baltimore)
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