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JOURNAL ARTICLE
Jing He, Zi-Xin Yang, Wen-Long Zhang, Hai-Zhou Zhang, Mei Zhu
OBJECTIVE: The objective of this study is to explore the patterns of alteration in left ventricular systolic function among patients with severe aortic stenosis (SAS) through the application of automatic myocardial motion quantification (aCMQ) techniques. Furthermore, we seek to ascertain dependable quantitative markers for the assessment of impaired left ventricular function in patients with SAS and an ejection fraction (EF) ≥ 60%. METHODS: Seventy patients who underwent echocardiography and received a diagnosis of severe aortic stenosis (SAS) in the hospital from November 2021 to August 2022 were selected for the SAS group and categorized into three subgroups based on ejection fraction (EF)-SAS group with EF ≥ 60%, SAS group with EF ranging from 50% to 59%, and SAS group with EF < 50%...
March 22, 2024: Ultrasound in Medicine & Biology
#22
JOURNAL ARTICLE
Rasmus Carter-Storch, Emma Le Nezet, Mulham Ali, Andréanne Powers, Amal Haujir, Karolanne Demers, Christian Couture, Éric Dumont, Sylvain Trahan, Sylvain Pagé, François Dagenais, Philippe Pibarot, Jordi S Dahl, Marie-Annick Clavel
BACKGROUND: Angiotensin receptor blockers (ARBs) may slow down the progression of aortic stenosis (AS), through their antifibrotic effect. Females present more valvular fibrosis than males, thus ARBs may have more effect in females. Our aim was to assess the impact of ARBs on the remodeling of the aortic valve in males and females. METHODS: We included patients who had an aortic valve replacement± coronary bypass grafting between 2006-2013. Patients with missing echocardiographic or histologic data were excluded...
March 20, 2024: Canadian Journal of Cardiology
#23
JOURNAL ARTICLE
Marco Ranucci, Vittoria Mazzotta, Martina Anguissola, Luca Ranucci, Luca Brischigiaro, Francesco Bedogni, Laura Adelaide Dalla Vecchia, Marianna Volpe, Maria Teresa La Rovere
No abstract text is available yet for this article.
March 21, 2024: European Journal of Preventive Cardiology
#24
JOURNAL ARTICLE
Eline Kho, Jimmy Schenk, Alexander P J Vlaar, Marije M Vis, Marije Wijnberge, Lotte B Stam, Martijn van Mourik, Harald T Jorstad, Henning Hermanns, Berend E Westerhof, Denise P Veelo, Bjorn J P van der Ster
The incidence of aortic valve stenosis (AoS) increases with age, and once diagnosed, symptomatic severe AoS has a yearly mortality rate of 25%. AoS is diagnosed with transthoracic echocardiography (TTE), however, this gold standard is time consuming and operator and acoustic window dependent. As AoS affects the arterial blood pressure waveform, AoS-specific waveform features might serve as a diagnostic tool. Aim of the present study was to develop a novel, non-invasive, AoS detection model based on blood pressures waveforms...
March 20, 2024: GeroScience
#25
JOURNAL ARTICLE
Philippe Unger, Andréanne Powers, Emma Le Nezet, Emilie Lacasse-Rioux, Xavier Galloo, Marie-Annick Clavel
BACKGROUND: Conflicting prognostic results have been reported in patients with discordant high-gradient aortic stenosis ([DHG-AS] the combination of a mean pressure gradient ≥40 mm Hg and an aortic valve area [AVA] >1 cm2 ). Moreover, existing studies only included selected patients without concomitant aortic regurgitation. OBJECTIVES: The authors assessed the prevalence and survival of patients presenting with DHG-AS in an unselected group of consecutive patients presenting to the echocardiography laboratory of a tertiary referral center...
March 26, 2024: Journal of the American College of Cardiology
#26
JOURNAL ARTICLE
Santiago Decotto, Giuliana Corna, Eugenia Villanueva, Diego Pérez-de Arenaza, Ignacio Seropian, Mariano Falconi, Pablo Oberti, Ma Adela Aguirre, Ma Lourdes Posadas-Martínez, Marcelina Carretero, Carla R Agatiello, Rodolfo Pizarro
BACKGROUND: Aortic stenosis (AS) is currently the most common valvular disease, with an estimated prevalence of over 4% in octogenarians. OBJECTIVE: To describe the prevalence of moderate-severe aortic stenosis (AS) in patients with wild type transthyretin amyloidosis (ATTRwt). Also, describe the clinical features, echocardiographic characteristics and clinical evolution. METHOD: Retrospective cohort of patients with diagnosis of ATTRwt, belonging to Hospital Italiano de Buenos Aires Institutional Amyloidosis Registry, from 30/11/2007 to 31/05/2021...
2024: Archivos de Cardiología de México
#27
JOURNAL ARTICLE
Hongyan Xiao, Laichun Song, Meng Guo, Liang Tao
We describe a 45-year-old patient who was diagnosed with hypertrophic obstructive cardiomyopathy (HOCM) after the aortic valve replacement surgery. Enlarged left atria, thickened ventricular septum, left ventricular outflow tract stenosis, moderate mitral regurgitation and mild tricuspid regurgitation in the echocardiography were found. We offered the patient the new minimally invasive treatment modality: percutaneous intra-myocardial septal radiofrequency ablation (PIMSRA). We demonstrate the safety and efficacy with pictures...
March 19, 2024: Journal of Cardiothoracic Surgery
#28
JOURNAL ARTICLE
Luis F Gonzalez-Ciccarelli, Renan A Ferrufino, Abdulaziz Alfadhel, Ethan Brovman, Jamel Ortoleva, Benjamin S Wessler, Michael Fettiplace, Frederick Cobey
OBJECTIVES: To determine the impact of pressure recovery (PR) adjustment on disease severity grading in patients with severe aortic stenosis. The authors hypothesized that accounting for PR would result in echocardiographic reclassification of aortic stenosis severity in a significant number of patients. DESIGN: A retrospective observational study between October 2013 and February 2021. SETTING: A single-center, quaternary-care academic center...
February 29, 2024: Journal of Cardiothoracic and Vascular Anesthesia
#29
JOURNAL ARTICLE
Kengo Terasaka, Masaomi Gohbara, Takeru Abe, Tomohiro Yoshii, Yohei Hanajima, Jin Kirigaya, Mutsuo Horii, Shinnosuke Kikuchi, Hidefumi Nakahashi, Kensuke Matsushita, Yugo Minamimoto, Kozo Okada, Yasushi Matsuzawa, Noriaki Iwahashi, Masami Kosuge, Teruyasu Sugano, Toshiaki Ebina, Kiyoshi Hibi
No medications have been reported to inhibit the progression of aortic valve stenosis (AS). The present study aimed to investigate whether evolocumab use is related to the slow progression of AS evaluated by serial echocardiography. This was a retrospective observational study from 2017 to 2022 at Yokohama City University Medical Center. Patients aged ≥ 18 with moderate AS were included. Exclusion criteria were (1) mild AS; (2) severe AS defined by maximum aortic valve (AV) velocity ≥ 4...
March 19, 2024: Heart and Vessels
#30
Pierre Rossignon, Sofia Morra, Quentin de Hemptinne, Didier de Cannière, Philippe Unger
BACKGROUND: Percutaneous transvenous mitral commissurotomy (PTMC) is the first-line therapy of clinically significant rheumatic mitral stenosis. While the procedure is generally safe, new onset or aggravation of mitral regurgitation (MR) may occur, mainly due to commissural splitting and, less frequently, to leaflet tear and chordal rupture. Papillary muscle rupture (PMR) is exceedingly rare in this setting. CASE SUMMARY: A 74-year-old woman with a history of aortic valve replacement and prior rheumatic mitral commissurotomy presented for worsening exercise intolerance and exertional dyspnoea...
March 2024: European Heart Journal. Case Reports
#31
JOURNAL ARTICLE
Michele Antonello, Michele Piazza, Sabrina Menara, Chiara Colacchio, Franco Grego, Mirko Menegolo, Francesco Squizzato
OBJECTIVES: to evaluate the role of intravascular ultrasound (IVUS) for the technical assessment of kissing stents (KS) and covered endovascular reconstruction of the aortic bifurcation (CERAB) in the treatment of aortoiliac obstructive disease involving the aortic bifurcation. METHODS: We conducted a single-center retrospective review of patients undergoing endovascular treatment of severe aorto-iliac obstructive disease (2019-2023). IVUS was performed in patients treated by KS or CERAB according to preoperative indications, in cases of moderate/severe calcifications, mural thrombus, total occlusions, and lesion extension towards the proximity of renal or hypogastric arteries...
March 12, 2024: Journal of Vascular Surgery
#32
Nicholas Roma, Kashyap Shah, Ketul Patel, Joshua Elmer, Bruce Ferraro, Prarthana Patel, Michael Durkin
UNLABELLED: Transcatheter aortic valve replacement (TAVR) is a less invasive alternative to an open surgical aortic valve replacement (SAVR) for treating severe symptomatic aortic stenosis. Despite gaining widespread acceptance and approval for use in patients with high, moderate, and low surgical risk, the increasing use of TAVR has raised concerns about potential short- and long-term complications. We present the case of a 69-year-old female who underwent TAVR and subsequently presented to our outpatient cardiology clinic with progressively worsening dyspnea, orthopnea, and paroxysmal nocturnal dyspnea two years after the procedure...
March 2024: Journal of Cardiology Cases
#33
JOURNAL ARTICLE
Andrea Scotti, Matteo Sturla, Giuliano Costa, Francesco Saia, Thomas Pilgrim, Mohamed Abdel-Wahab, Philippe Garot, Caterina Gandolfo, Luca Branca, Ignacio Amat Santos, Darren Mylotte, Francesco Bedogni, Ole De Backer, Luis Nombela Franco, John Webb, Flavio Luciano Ribichini, Andrea Mainardi, Stefano Andreaggi, Alessandro Mazzapicchi, Daijiro Tomii, Pietro Laforgia, Stefano Cannata, Claudia Fiorina, Simone Fezzi, Enrico Criscione, Mattia Lunardi, Enrico Poletti, Mattia Mazzucca, Angelo Quagliana, Nicholas Montarello, Breda Hennessey, Matias Mon-Noboa, Myriam Akodad, David Meier, Federico De Marco, Marianna Adamo, Carmelo Sgroi, Claudia Maria Reddavid, Roberto Valvo, Orazio Strazzieri, Silvia Crescenzia Motta, Valentina Frittitta, Elena Dipietro, Alessandro Comis, Chiara Melfa, Mariachiara Calì, Sofia Sammartino, Giulia Laterra, Holger Thiele, Lars Sondergaard, Corrado Tamburino, Marco Barbanti, Azeem Latib
BACKGROUND: The performance of latest iteration transcatheter aortic valve replacement platforms in patients with small aortic anatomy remains underexplored. OBJECTIVES: The aim of this study was to evaluate effectiveness and performance between the self-expanding (SE) Evolut PRO and PRO+ and the balloon-expandable (BE) SAPIEN ULTRA in patients with small aortic annuli. METHODS: Data from the OPERA-TAVI (Comparative Analysis of Evolut PRO vs...
March 11, 2024: JACC. Cardiovascular Interventions
#34
Vlasta M E Fesslova, Martina Evangelista, Luciane Piazza, Antonio Saracino, Andreea Andronache, Carmelina Chiarello, Alessandro Varrica, Alessandro Giamberti, Alessandro Frigiola
We describe a case of a voluminous rhabdomyoma (R) detected by fetal echocardiography at 32 weeks' gestation (w.g.) obstructing the left ventricular inflow and aortic outflow tract, with a moderate aortic gradient at birth, not needing immediate surgery. At follow-up, the mass progressively regressed, leaving the aortic valve partly damaged, with a gradient that increased to a maximum of 100 mmHg at 9 years. The girl was then operated on successfully by a plasty of the aortic valve. The literature regarding R is discussed...
February 21, 2024: Diagnostics
#35
JOURNAL ARTICLE
Dejing Feng, Jie Zhao, Guannan Niu, Yuxuan Zhang, Can Wang, Yang Chen, Zheng Zhou, Hongliang Zhang, Zhenyan Zhao, Yunqing Ye, Zhe Li, Haiyan Xu, Moyang Wang, Yongjian Wu
BACKGROUND: We aim to compare the short and long-term outcomes for aortic stenosis (AS) patients undergone TAVR with and without ascending aorta dilation (AAD). METHODS: Consecutive patients diagnosed with native severe AS who underwent TAVR from September 2012 to September 2021 were enrolled. They were stratified into the moderate/severe dilation group (greatest ascending aorta width ≥ 45 mm) and the non/mild dilation group. Survival outcomes were illustrated using Kaplan-Meier curves and evaluated with the log-rank test...
March 10, 2024: International Journal of Cardiology
#36
JOURNAL ARTICLE
Naoya Inoue, Hayato Ohtani, Shuji Morikawa, Yohei Takayama, Takashi Ogane, Takehiro Hiramatsu, Hiroki Kumihashi, Toyoaki Murohara
BACKGROUND: Cardiovascular events are increasing in patients with supranormal left ventricular ejection fraction (snLVEF). However, the effect of snLVEF in patients with aortic stenosis (AS) remains unclear, especially in patients with moderate AS. HYPOTHESIS: This study aimed to evaluate the prognosis of mortality and heart failure (HF) in patients with LVEF ≥ 50% and moderate or severe AS. METHODS: This retrospective study targeted patients with moderate or severe AS and LVEF > 50%...
March 2024: Clinical Cardiology
#37
JOURNAL ARTICLE
Martin Beyer, Till Joscha Demal, Oliver D Bhadra, Matthias Linder, Sebastian Ludwig, David Grundmann, Lisa Voigtlaender-Buschmann, Lara Waldschmidt, Johannes Schirmer, Niklas Schofer, Simon Pecha, Stefan Blankenberg, Hermann Reichenspurner, Lenard Conradi, Moritz Seiffert, Andreas Schaefer
BACKGROUND: Previous reports suggest septal hypertrophy with an interventricular septum depth (IVSD) ≥ 14 mm may adversely affect outcomes after transcatheter aortic valve implantation (TAVI) due to suboptimal valve placement, valve migration, or residual increased LVOT pressure gradients. AIMS: This analysis investigates the impact of interventricular septal hypertrophy on acute outcomes after TAVI. METHODS: Between 2009 and 2021, 1033 consecutive patients (55...
March 11, 2024: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
#38
César Jiménez-Méndez, Ana Pérez-Asensio, Livia Gheorghe, William Delgado Nava, Rafael Vázquez-García
A 70-year-old woman consulted us for dyspnea. Echocardiography revealed moderate aortic regurgitation secondary to ascending aorta dilatation. Study was completed with aortic angiography computed tomography, showing stenosis and dissection of several visceral arteries. There were no abnormal inflammatory or autoimmune markers, nor fluorine-18-fluorodeoxyglucose positron emission tomography uptake. Segmental arterial mediolysis was diagnosed.
March 6, 2024: JACC. Case reports
#39
JOURNAL ARTICLE
Manish Vinayak, Gilbert H L Tang, Keva Li, Megan Berdan, Anoop N Koshy, Sahil Khera, Stamatios Lerakis, George D Dangas, Samin K Sharma, Annapoorna S Kini, Parasuram Krishnamoorthy
BACKGROUND: Coronary alignment is proposed as an alternative to commissural alignment for reducing coronary overlap during transcatheter aortic valve replacement (TAVR). However, largescale studies are lacking. OBJECTIVES: This study aimed to determine the incidence of coronary overlap with commissural vs coronary alignment using computed tomography (CT) simulation in patients undergoing TAVR evaluation. METHODS: In 1,851 CT scans of native aortic stenosis patients undergoing TAVR evaluation (April 2018 to December 2022),virtual valves simulating commissural and coronary alignment were superimposed on axial aortic root images...
February 23, 2024: JACC. Cardiovascular Interventions
#40
Salvatore Evola, Alessandro D'Agostino, Daniele Adorno, Oreste Fabio Triolo, Gioacchino Giarratana, Sebastiano Castrovinci, Vincenzo Argano, Eustaquio Maria Onorato
BACKGROUND: Closure of paravalvular leak (PVL) regurgitation after self-expandable (SE) transcatheter aortic valve implantation (TAVI) may be more challenging than after balloon-expandable (BE) valve implantation. CASE SUMMARY: An 85-year-old woman suffering from long-standing atrial fibrillation and severe symptomatic aortic stenosis underwent SE TAVI (26 mm Evolut™ R®, Medtronic Inc., MN, USA). A total of eighteen months after TAVI she was admitted for congestive heart failure and two-dimensional (2D) transesophageal echocardiography (TEE) color Doppler showed moderate-severe PVL regurgitation due to a long and heavily calcified leak located below the left coronary sinus...
2024: Frontiers in Cardiovascular Medicine
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