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https://www.readbyqxmd.com/read/28925997/precision-annotation-of-digital-samples-in-ncbi-s-gene-expression-omnibus
#1
Dexter Hadley, James Pan, Osama El-Sayed, Jihad Aljabban, Imad Aljabban, Tej D Azad, Mohamad O Hadied, Shuaib Raza, Benjamin Abhishek Rayikanti, Bin Chen, Hyojung Paik, Dvir Aran, Jordan Spatz, Daniel Himmelstein, Maryam Panahiazar, Sanchita Bhattacharya, Marina Sirota, Mark A Musen, Atul J Butte
The Gene Expression Omnibus (GEO) contains more than two million digital samples from functional genomics experiments amassed over almost two decades. However, individual sample meta-data remains poorly described by unstructured free text attributes preventing its largescale reanalysis. We introduce the Search Tag Analyze Resource for GEO as a web application (http://STARGEO.org) to curate better annotations of sample phenotypes uniformly across different studies, and to use these sample annotations to define robust genomic signatures of disease pathology by meta-analysis...
September 19, 2017: Scientific Data
https://www.readbyqxmd.com/read/28916566/perspective-essential-study-quality-descriptors-for-data-from-nutritional-epidemiologic-research
#2
Chen Yang, Mariona Pinart, Patrick Kolsteren, John Van Camp, Nathalie De Cock, Katharina Nimptsch, Tobias Pischon, Eamon Laird, Giuditta Perozzi, Raffaella Canali, Axelle Hoge, Marta Stelmach-Mardas, Lars Ove Dragsted, Stéphanie Maria Palombi, Irina Dobre, Jildau Bouwman, Peter Clarys, Fabio Minervini, Maria De Angelis, Marco Gobbetti, Jean Tafforeau, Oscar Coltell, Dolores Corella, Hendrik De Ruyck, Janette Walton, Laura Kehoe, Christophe Matthys, Bernard De Baets, Guy De Tré, Antoon Bronselaer, Angela Rivellese, Rosalba Giacco, Rosario Lombardo, Sofian De Clercq, Niels Hulstaert, Carl Lachat
Pooled analysis of secondary data increases the power of research and enables scientific discovery in nutritional epidemiology. Information on study characteristics that determine data quality is needed to enable correct reuse and interpretation of data. This study aims to define essential quality characteristics for data from observational studies in nutrition. First, a literature review was performed to get an insight on existing instruments that assess the quality of cohort, case-control, and cross-sectional studies and dietary measurement...
September 2017: Advances in Nutrition
https://www.readbyqxmd.com/read/28903073/reconciling-disparate-information-in-continuity-of-care-documents-piloting-a-system-to-consolidate-structured-clinical-documents
#3
Masoud Hosseini, Josette Jones, Anthony Faiola, Daniel J Vreeman, Huanmei Wu, Brian E Dixon
BACKGROUND: Due to the nature of information generation in health care, clinical documents contain duplicate and sometimes conflicting information. Recent implementation of health information exchange (HIE) mechanisms in which clinical summary documents are exchanged among disparate health care organizations can proliferate duplicate and conflicting information. MATERIALS AND METHODS: To reduce information overload, a system to automatically consolidate information across multiple clinical summary documents was developed for an HIE network...
September 10, 2017: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/28899575/ehealth-in-integrated-care-programs-for-people-with-multimorbidity-in-europe-insights-from-the-icare4eu-project
#4
Maria Gabriella Melchiorre, Roberta Papa, Mieke Rijken, Ewout van Ginneken, Anneli Hujala, Francesco Barbabella
INTRODUCTION: Care for people with multimorbidity requires an integrated approach in order to adequately meet their complex needs. In this respect eHealth could be of help. This paper aims to describe the implementation, as well as benefits and barriers of eHealth applications in integrated care programs targeting people with multimorbidity in European countries, including insights on older people 65+. METHODS: Within the framework of the ICARE4EU project, in 2014, expert organizations in 24 European countries identified 101 integrated care programs based on selected inclusion criteria...
August 12, 2017: Health Policy
https://www.readbyqxmd.com/read/28899449/the-provider-perspective-investigating-the-effect-of-the-electronic-patient-reported-outcome-epro-mobile-application-and-portal-on-primary-care-provider-workflow
#5
Parminder K Hans, Carolyn Steele Gray, Ashlinder Gill, James Tiessen
Aim This qualitative study investigates how the Electronic Patient-Reported Outcome (ePRO) mobile application and portal system, designed to capture patient-reported measures to support self-management, affected primary care provider workflows. BACKGROUND: The Canadian health system is facing an ageing population that is living with chronic disease. Disruptive innovations like mobile health technologies can help to support health system transformation needed to better meet the multifaceted needs of the complex care patient...
September 13, 2017: Primary Health Care Research & Development
https://www.readbyqxmd.com/read/28891182/rare-disease-registries-a-call-to-action
#6
Paul Lacaze, Nicole Millis, Megan Fookes, Yvonne Zurynski, Adam Jaffe, Matthew Bellgard, Ingrid Winship, John McNeil, Alan H Bittles
When registries collect accurate clinical data over time, they can act as fundamental support structures for patients and their families and powerful cost-effective instruments to support clinical trials and translational research to improve quality of care, quality of life and survival. Registries are critical for rare diseases (RD) with low prevalence and propensity for variation in treatment and outcomes. Rare Voices Australia is leading a call for action to the research and clinical community to prioritise RD data collection and develop an integrated RD Registry strategy for Australia...
September 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/28890644/ehrs-the-challenge-of-making-electronic-data-usable-and-interoperable
#7
Miriam Reisman
Despite massive effort and investment in health information systems and technology, the promised benefits of electronic health records (EHRs) are far from fruition. The author presents the legislative programs that encourage the implementation of EHRs and explores the barriers hampering interoperability.
September 2017: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/28883197/an-abstraction-layer-to-facilitate-technical-interoperability-between-medical-records-and-knowledge-modules
#8
Martin Staudigel, Hans-Ulrich Prokosch, Stefan Kraus
Integrating clinical decision support (CDS) functions into an existing hospital information system (HIS) is often a tedious task. This problem area is so pervasive that the Arden Syntax, a widely used standard for CDS functions, assigned a specific designation, the so-called "curly braces problem". It derives from a pair of curly braces used to encapsulate any parameters required for the interactions with a HIS. The traditional approach is to leave the problem area of technical interoperability entirely to the specific institution, possibly entailing a considerable amount of initial programming work...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28883195/mapping-equivalence-of-german-emergency-department-medical-record-concepts-with-snomed-ct-after-implementation-with-hl7-cda
#9
Dominik Brammen, Heike Dewenter, Kai U Heitmann, Volker Thiemann, Raphael W Majeed, Felix Walcher, Rainer Röhrig, Sylvia Thun
INTRODUCTION: The German Emergency Department Medical Record (GEDMR) was created by medical domain experts and healthcare providers providing a dataset as well as a form. The trauma module of GEDMR was syntactically standardized using HL7 CDA and semantically standardized using different terminologies including SNOMED CT, LOINC and proprietary coding systems. This study depicts the mapping accuracy with aforementioned syntactical and semantical standards in general and especially the content coverage of SNOMED CT...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28883192/6-interoperability-standards-terminologies-classification
#10
(no author information available yet)
No abstract text is available yet for this article.
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28883186/disseminating-a-standard-for-medical-records-in-emergency-departments-among-different-software-vendors-using-hl7-cda
#11
Dominik Brammen, Heike Dewenter, Volker Thiemann, Raphael W Majeed, Tingyan Xu, Kai U Heitmann, Felix Walcher, Sylvia Thun, Rainer Röhrig
A standardized medical record for the emergency department (GEDMR) was released in Germany, but only sparsely and randomly implemented by emergency department (ED) electronic health record (EHR) vendors. A reason for this may be a lacking common language between the medical and the Health Information Technology (HIT) domain. HL7 clinical document architecture (CDA) may leverage this communication gap. This paper reports on the effects of a professional medical association record standard on EHR vendors and the German ED-EHR market...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28881939/data-management-rubric-for-video-data-in-organismal-biology
#12
Elizabeth L Brainerd, Richard W Blob, Tyson L Hedrick, Andrew T Creamer, Ulrike K Müller
Standards-based data management facilitates data preservation, discoverability, and access for effective data reuse within research groups and across communities of researchers. Data sharing requires community consensus on standards for data management, such as storage and formats for digital data preservation, metadata (i.e., contextual data about the data) that should be recorded and stored, and data access. Video imaging is a valuable tool for measuring time-varying phenotypes in organismal biology, with particular application for research in functional morphology, comparative biomechanics, and animal behavior...
July 1, 2017: Integrative and Comparative Biology
https://www.readbyqxmd.com/read/28873968/high-precision-registration-between-zebrafish-brain-atlases-using-symmetric-diffeomorphic-normalization
#13
Gregory D Marquart, Kathryn M Tabor, Eric J Horstick, Mary Brown, Alexandra K Geoca, Nicholas F Polys, Damian Dalle Nogare, Harold A Burgess
Atlases provide a framework for spatially mapping information from diverse sources into a common reference space. Specifically, brain atlases allow annotation of gene expression, cell morphology, connectivity, and activity. In larval zebrafish, advances in genetics, imaging, and computational methods now allow the collection of such information brain-wide. However, due to technical considerations, disparate datasets may use different references and may not be aligned to the same coordinate space. Two recent larval zebrafish atlases exemplify this problem: Z-Brain, containing gene expression, neural activity, and neuroanatomical segmentations, was acquired using immunohistochemical stains, while the Zebrafish Brain Browser (ZBB) was constructed from live scans of fluorescent reporters in transgenic larvae...
August 1, 2017: GigaScience
https://www.readbyqxmd.com/read/28873787/the-need-for-information-on-standards-on-eaccessibility-einclusion-based-on-the-experience-of-the-eu-project-in-life
#14
Christian Galinski, Blanca Stella Giraldo Perez
Recent investigations in several EU-projects, incl. IN LIFE revealed that experts in the field of eAccessibility & eInclusion (eAcc&eIncl) - but also general ICT developers, decision makers in industry and administration - are quite unaware of the importance of standards for interoperability and sustainability of ICT solutions. Especially, if persons with disabilities (PwD) are concerned, system development and the design of services can become unnecessarily costly. For accessibility in general and eAcc&eIncl in particular, knowing about pertinent standards is becoming an asset of personal competencies of experts and decision makers, and particularly benefit small enterprises...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28870259/rdfio-extending-semantic-mediawiki-for-interoperable-biomedical-data-management
#15
Samuel Lampa, Egon Willighagen, Pekka Kohonen, Ali King, Denny Vrandečić, Roland Grafström, Ola Spjuth
BACKGROUND: Biological sciences are characterised not only by an increasing amount but also the extreme complexity of its data. This stresses the need for efficient ways of integrating these data in a coherent description of biological systems. In many cases, biological data needs organization before integration. This is not seldom a collaborative effort, and it is thus important that tools for data integration support a collaborative way of working. Wiki systems with support for structured semantic data authoring, such as Semantic MediaWiki, provide a powerful solution for collaborative editing of data combined with machine-readability, so that data can be handled in an automated fashion in any downstream analyses...
September 4, 2017: Journal of Biomedical Semantics
https://www.readbyqxmd.com/read/28867640/development-and-validation-of-a-teaching-module-for-echocardiographic-scoring-of-rheumatic-mitral-stenosis
#16
Nathan Stehouwer, Emmy Okello, Vedant Gupta, Alison L Bailey, Richard Josephson, Sri Krishna Madan Mohan, Mohammed N Osman, Chris T Longenecker
BACKGROUND: The Wilkins score and commissural calcification scores predict outcomes after percutaneous balloon mitral valvuloplasty. However, many cardiologists are inadequately trained in their application-both in the United States where the incidence of rheumatic heart disease has fallen and in rheumatic heart disease endemic countries where training infrastructure is weak. OBJECTIVES: This study sought to develop a computer-based educational module teaching 2 scoring systems for rheumatic mitral stenosis and to validate the module among cardiology fellows in the United States and Uganda...
August 31, 2017: Global Heart
https://www.readbyqxmd.com/read/28859829/multi-model-based-interactive-authoring-environment-for-creating-shareable-medical-knowledge
#17
Taqdir Ali, Maqbool Hussain, Wajahat Ali Khan, Muhammad Afzal, Jamil Hussain, Rahman Ali, Waseem Hassan, Arif Jamshed, Byeong Ho Kang, Sungyoung Lee
OBJECTIVE: Technologically integrated healthcare environments can be realized if physicians are encouraged to use smart systems for the creation and sharing of knowledge used in clinical decision support systems (CDSS). While CDSSs are heading toward smart environments, they lack support for abstraction of technology-oriented knowledge from physicians. Therefore, abstraction in the form of a user-friendly and flexible authoring environment is required in order for physicians to create shareable and interoperable knowledge for CDSS workflows...
October 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28855343/medical-support-to-military-airborne-training-and-operations
#18
Kerry J Starkey, J Lyon, E Sigman, H J Pynn, G Nordmann
INTRODUCTION: Airborne operations enable large numbers of military forces to deploy on the ground in the shortest possible time. This however must be balanced by an increased risk of injury. The aim of this paper is to review the current UK military drop zone medical estimate process, which may help to predict the risk of potential injury and assist in planning appropriate levels of medical support. METHOD: In spring 2015, a British Airborne Battlegroup (UKBG) deployed on a 7-week overseas interoperability training exercise in the USA with their American counterparts (USBG)...
August 30, 2017: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/28855008/pharmacy-and-ehr-information-exchange-a-national-summit
#19
Joanne Kaldy
Pharmacists and other practitioners increasingly must focus on data collection, analysis, and communication to maximize quality and reduce adverse events that lead to readmissions. As a result, they are seeking systems and software that provide them with real-time access to the information they need and enable them to communicate with other stakeholders. To date, there have been barriers, including lack of system/software interoperability and electronic health records that make it difficult for practitioners to access and/or input data...
September 1, 2017: Consultant Pharmacist: the Journal of the American Society of Consultant Pharmacists
https://www.readbyqxmd.com/read/28851681/is-there-evidence-of-cost-benefits-of-electronic-medical-records-standards-or-interoperability-in-hospital-information-systems-overview-of-systematic-reviews
#20
Zilma Silveira Nogueira Reis, Thais Abreu Maia, Milena Soriano Marcolino, Francisco Becerra-Posada, David Novillo-Ortiz, Antonio Luiz Pinho Ribeiro
BACKGROUND: Electronic health (eHealth) interventions may improve the quality of care by providing timely, accessible information about one patient or an entire population. Electronic patient care information forms the nucleus of computerized health information systems. However, interoperability among systems depends on the adoption of information standards. Additionally, investing in technology systems requires cost-effectiveness studies to ensure the sustainability of processes for stakeholders...
August 29, 2017: JMIR Medical Informatics
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