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https://www.readbyqxmd.com/read/27914177/virtual-touch-tissue-imaging-and-quantification-in-the-evaluation-of-thyroid-nodules
#1
Hang Zhou, Xian-Li Zhou, Hui-Xiong Xu, Dan-Dan Li, Bo-Ji Liu, Yi-Feng Zhang, Jun-Mei Xu, Xiao-Wan Bo, Xiao-Long Li, Le-Hang Guo, Shen Qu
OBJECTIVES: To investigate the diagnostic performance of a 2-dimensional shear wave elastographic technique (Virtual Touch tissue imaging and quantification [VTIQ]; Siemens Medical Solutions, Mountain View, CA) for predicting thyroid malignancy. METHODS: A total of 302 thyroid nodules underwent conventional sonography and VTIQ before fine-needle aspiration examination or surgery. Compared with histopathologic or cytologic results in combination with follow-up, the diagnostic performance of various shear wave speed (SWS) indices (minimum [SWSmin ], maximum [SWSmax ], and mean [SWSmean ]) on VTIQ as well as conventional sonographic features for predicting thyroid malignancy was evaluated in all of the nodules...
December 3, 2016: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/27902547/ambulatory-electronic-health-records-must-be-more-interoperable-to-support-optimal-practice
#2
Alan E Zuckerman
No abstract text is available yet for this article.
January 2017: Journal of Ambulatory Care Management
https://www.readbyqxmd.com/read/27899646/fairdomhub-a-repository-and-collaboration-environment-for-sharing-systems-biology-research
#3
Katherine Wolstencroft, Olga Krebs, Jacky L Snoep, Natalie J Stanford, Finn Bacall, Martin Golebiewski, Rostyk Kuzyakiv, Quyen Nguyen, Stuart Owen, Stian Soiland-Reyes, Jakub Straszewski, David D van Niekerk, Alan R Williams, Lars Malmström, Bernd Rinn, Wolfgang Müller, Carole Goble
The FAIRDOMHub is a repository for publishing FAIR (Findable, Accessible, Interoperable and Reusable) Data, Operating procedures and Models (https://fairdomhub.org/) for the Systems Biology community. It is a web-accessible repository for storing and sharing systems biology research assets. It enables researchers to organize, share and publish data, models and protocols, interlink them in the context of the systems biology investigations that produced them, and to interrogate them via API interfaces. By using the FAIRDOMHub, researchers can achieve more effective exchange with geographically distributed collaborators during projects, ensure results are sustained and preserved and generate reproducible publications that adhere to the FAIR guiding principles of data stewardship...
November 28, 2016: Nucleic Acids Research
https://www.readbyqxmd.com/read/27896971/rabix-an-open-source-workflow-executor-supporting-recomputability-and-interoperability-of-workflow-descriptions
#4
Gaurav Kaushik, Sinisa Ivkovic, Janko Simonovic, Nebojsa Tijanic, Brandi Davis-Dusenbery, Deniz Kural
As biomedical data has become increasingly easy to generate in large quantities, the methods used to analyze it have proliferated rapidly. Reproducible and reusable methods are required to learn from large volumes of data reliably. To address this issue, numerous groups have developed workflow specifications or execution engines, which provide a framework with which to perform a sequence of analyses. One such specification is the Common Workflow Language, an emerging standard which provides a robust and flexible framework for describing data analysis tools and workflows...
2016: Pacific Symposium on Biocomputing
https://www.readbyqxmd.com/read/27895957/adoption-of-electronic-health-records-a-roadmap-for-india
#5
REVIEW
Sunil Kumar Srivastava
OBJECTIVES: The objective of the study was to create a roadmap for the adoption of Electronic Health Record (EHR) in India based an analysis of the strategies of other countries and national scenarios of ICT use in India. METHODS: The strategies for adoption of EHR in other countries were analyzed to find the crucial steps taken. Apart from reports collected from stakeholders in the country, the study relied on the experience of the author in handling several e-health projects...
October 2016: Healthcare Informatics Research
https://www.readbyqxmd.com/read/27892420/ehealth-in-cardiovascular-medicine-a-clinical-update
#6
Hugo Saner, Enno van der Velde
Demographic changes, progress in medicine technology and regional problems in providing healthcare to low density populations are posing great challenges to our healthcare systems. Rapid progress in computer sciences and information technologies have a great impact on the way healthcare will be delivered in the near future. This article describes opportunities and challenges of eHealth and telemedicine in the framework of our health systems and, in particular, in the context of today's cardiology services. The most promising applications of eHealth and telemedicine include: (a) prevention and lifestyle interventions; (b) chronic disease management including hypertension, diabetes and heart failure; (c) arrhythmia detection including early detection of atrial fibrillation and telemonitoring of devices such as pacemaker, internal cardioverter defibrillators and implantable rhythm monitoring devices; (d) telerehabilitation...
October 2016: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/27888231/text-mining-resources-for-the-life-sciences
#7
REVIEW
Piotr Przybyła, Matthew Shardlow, Sophie Aubin, Robert Bossy, Richard Eckart de Castilho, Stelios Piperidis, John McNaught, Sophia Ananiadou
Text mining is a powerful technology for quickly distilling key information from vast quantities of biomedical literature. However, to harness this power the researcher must be well versed in the availability, suitability, adaptability, interoperability and comparative accuracy of current text mining resources. In this survey, we give an overview of the text mining resources that exist in the life sciences to help researchers, especially those employed in biocuration, to engage with text mining in their own work...
2016: Database: the Journal of Biological Databases and Curation
https://www.readbyqxmd.com/read/27886091/a-testbed-to-evaluate-the-fiware-based-iot-platform-in-the-domain-of-precision-agriculture
#8
Ramón Martínez, Juan Ángel Pastor, Bárbara Álvarez, Andrés Iborra
Wireless sensor networks (WSNs) represent one of the most promising technologies for precision farming. Over the next few years, a significant increase in the use of such systems on commercial farms is expected. WSNs present a number of problems, regarding scalability, interoperability, communications, connectivity with databases and data processing. Different Internet of Things middleware is appearing to overcome these challenges. This paper checks whether one of these middleware, FIWARE, is suitable for the development of agricultural applications...
November 23, 2016: Sensors
https://www.readbyqxmd.com/read/27886016/an-internet-of-things-platform-architecture-for-supporting-ambient-assisted-living-environments
#9
Charalampos Tsirmpas, Ioannis Kouris, Athanasios Anastasiou, Kostas Giokas, Dimitra Iliopoulou, Dimitris Koutsouris
Internet of Things (IoT) is the logical further development of today's Internet, enabling a huge amount of devices to communicate, compute, sense and act. IoT sensors placed in Ambient Assisted Living (AAL) environments, enable the context awareness and allow the support of the elderly in their daily routines, ultimately allowing an independent and safe lifestyle. The vast amount of data that are generated and exchanged between the IoT nodes require innovative context modeling approaches that go beyond currently used models...
November 18, 2016: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/27883119/gtcbio-s-precision-medicine-conference-july-7-8-2016-boston-massachusetts-usa
#10
P Cole
GTCBio's Precision Medicine Conference met this year to outline the many steps forward that precision medicine and individualized genomics has made and the challenges it still faces in technological, modeling, and standards development, interoperability and compatibility advancements, and methods of economic and societal adoption. The conference was split into four sections, 'Overcoming Challenges in the Commercialization of Precision Medicine', 'Implementation of Precision Medicine: Strategies & Technologies', 'Integrating & Interpreting Personal Genomics, Big Data, & Bioinformatics' and 'Incentivizing Precision Medicine: Regulation & Reimbursement', with this report focusing on the final two subjects...
September 2016: Drugs of Today
https://www.readbyqxmd.com/read/27877892/towards-a-metadata-scheme-for-the-description-of-materials-the-description-of-microstructures
#11
Georg J Schmitz, Bernd Böttger, Markus Apel, Janin Eiken, Gottfried Laschet, Ralph Altenfeld, Ralf Berger, Guillaume Boussinot, Alexandre Viardin
The property of any material is essentially determined by its microstructure. Numerical models are increasingly the focus of modern engineering as helpful tools for tailoring and optimization of custom-designed microstructures by suitable processing and alloy design. A huge variety of software tools is available to predict various microstructural aspects for different materials. In the general frame of an integrated computational materials engineering (ICME) approach, these microstructure models provide the link between models operating at the atomistic or electronic scales, and models operating on the macroscopic scale of the component and its processing...
2016: Science and Technology of Advanced Materials
https://www.readbyqxmd.com/read/27876374/characterizing-light-attenuation-within-northwest-florida-estuaries-implications-for-restore-act-water-quality-monitoring
#12
Robyn N Conmy, Blake A Schaeffer, Joseph Schubauer-Berigan, Jessica Aukamp, Allyn Duffy, John C Lehrter, Richard M Greene
Water Quality (WQ) condition is based on ecosystem stressor indicators (e.g. water clarity) which are biogeochemically important and critical when considering the Deepwater Horizon oil spill restoration efforts under the 2012 RESTORE Act. Nearly all of the proposed RESTORE projects list restoring WC as a goal, but 90% neglect water clarity. Here, dynamics of optical constituents impacting clarity are presented from a 2009-2011 study within Pensacola, Choctawhatchee, St. Andrew and St. Joseph estuaries (targeted RESTORE sites) in Northwest Florida...
November 19, 2016: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/27872873/postediting-prostate-magnetic-resonance-imaging-segmentation-consistency-and-operator-time-using-manual-and-computer-assisted-segmentation-multiobserver-study
#13
Maysam Shahedi, Derek W Cool, Cesare Romagnoli, Glenn S Bauman, Matthew Bastian-Jordan, George Rodrigues, Belal Ahmad, Michael Lock, Aaron Fenster, Aaron D Ward
Prostate segmentation on T2w MRI is important for several diagnostic and therapeutic procedures for prostate cancer. Manual segmentation is time-consuming, labor-intensive, and subject to high interobserver variability. This study investigated the suitability of computer-assisted segmentation algorithms for clinical translation, based on measurements of interoperator variability and measurements of the editing time required to yield clinically acceptable segmentations. A multioperator pilot study was performed under three pre- and postediting conditions: manual, semiautomatic, and automatic segmentation...
October 2016: Journal of Medical Imaging
https://www.readbyqxmd.com/read/27872033/a-review-of-visual-representations-of-physiologic-data
#14
REVIEW
Rishikesan Kamaleswaran, Carolyn McGregor
BACKGROUND: Physiological data is derived from electrodes attached directly to patients. Modern patient monitors are capable of sampling data at frequencies in the range of several million bits every hour. Hence the potential for cognitive threat arising from information overload and diminished situational awareness becomes increasingly relevant. A systematic review was conducted to identify novel visual representations of physiologic data that address cognitive, analytic, and monitoring requirements in critical care environments...
November 21, 2016: JMIR Medical Informatics
https://www.readbyqxmd.com/read/27871704/accuracy-and-reliability-of-orthodontists-using-cone-beam-computerized-tomography-for-assessment-of-adenoid-hypertrophy
#15
Camila Pachêco-Pereira, Noura A Alsufyani, Michael Major, Giseon Heo, Carlos Flores-Mir
INTRODUCTION: Our objectives were to evaluate the reliability of agreement between orthodontists, with various degrees of cone-beam computed tomography (CBCT) imaging manipulation comfort, in classifying adenoid hypertrophy through CBCT generated images and also to determine how accurate orthodontists are compared with the gold standard diagnosis, nasopharyngoscopy. METHODS: This was a cross-sectional study in which a randomized list of board-certified orthodontists evaluated different degrees of adenoid hypertrophy of a stratified sampling of 10 scans...
November 2016: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/27869583/patient-facing-technology-for-identification-of-copd-in-primary-care
#16
David Kevin Ahern, Donna Parker, Charles Eaton, Caitlin Rafferty, Joseph Wroblewski, Roberta Goldman
BACKGROUND: The proliferation of mobile devices and emergence of interoperable 'mHealth' apps is accelerating development and deployment of patient-facing risk assessments in primary care. The present study describes a user-centered design and an agile development approach to creation of an app for assessing lungfunction as part of a randomized controlled trial for the   dentification of chronic obstructive lung disease in primary care. METHOD: Seventeen patients recruited from a hospital-based, ambulatory family medicine clinic agreed to be videotaped while using the app, Lung Age, on a first-generation iPad prior to their provideR encounter...
July 15, 2016: Journal of Innovation in Health Informatics
https://www.readbyqxmd.com/read/27867738/evaluation-of-electrical-impedance-spectroscopy-as-an-adjunct-to-dermoscopy-in-short-term-monitoring-of-atypical-melanocytic-lesions
#17
Hannah Ceder, Alexandra Sjöholm Hylén, Ann-Marie Wennberg Larkö, John Paoli
BACKGROUND: Early detection of melanoma is vital for treatment outcome and survival. Short-term sequential digital dermoscopic monitoring (ST-SDDM) involves the capture and assessment of dermoscopic images of one or more atypical melanocytic lesions (AMLs), at baseline and after four months, in order to detect early morphologic changes. Electrical impedance spectroscopy (EIS) is a diagnostic tool with high sensitivity for the detection of malignant melanocytic lesions. OBJECTIVES: The aim of this study was to assess whether EIS, in addition to ST-SDDM, could improve the selection of AMLs requiring surgery...
October 2016: Dermatology Practical & Conceptual
https://www.readbyqxmd.com/read/27863463/the-chip-seq-tools-and-web-server-a-resource-for-analyzing-chip-seq-and-other-types-of-genomic-data
#18
Giovanna Ambrosini, René Dreos, Sunil Kumar, Philipp Bucher
BACKGROUND: ChIP-seq and related high-throughput chromatin profilig assays generate ever increasing volumes of highly valuable biological data. To make sense out of it, biologists need versatile, efficient and user-friendly tools for access, visualization and itegrative analysis of such data. RESULTS: Here we present the ChIP-Seq command line tools and web server, implementing basic algorithms for ChIP-seq data analysis starting with a read alignment file. The tools are optimized for memory-efficiency and speed thus allowing for processing of large data volumes on inexpensive hardware...
November 18, 2016: BMC Genomics
https://www.readbyqxmd.com/read/27855830/clinical-documentation-of-dental-care-in-an-era-of-electronic-health-record-use
#19
Oluwabunmi Tokede, Rachel B Ramoni, Michael Patton, John D Da Silva, Elsbeth Kalenderian
BACKGROUND: Although complete and accurate clinical records do not guarantee the provision of excellent dental care, they do provide an opportunity to evaluate the quality of care provided. However, a lack of universally accepted documentation standards, incomplete record-keeping practices, and unfriendly electronic health care record (EHR) user interfaces are factors that have allowed for persistent poor dental patient record keeping. METHODS: Using 2 different methods-a validated survey, and a 2-round Delphi process-involving 2 appropriately different sets of participants, we explored what a dental clinical record should contain and the frequency of update of each clinical entry...
September 2016: Journal of Evidence-based Dental Practice
https://www.readbyqxmd.com/read/27855394/prenasal-thickness-prefrontal-space-ratio-and-other-facial-profile-markers-in-first-trimester-fetuses-with-aneuploidies-cleft-palate-and-micrognathia
#20
Merel Bakker, Margherita Pace, Els de Jong-Pleij, Erwin Birnie, Karl-Oliver Kagan, Caterina M Bilardo
OBJECTIVE: To investigate the feasibility and reproducibility of the prenasal thickness (PNT)/nasal bone length (NBL) ratio, maxilla-nasion-mandible (MNM) angle, facial profile line, profile line distance, and prefrontal space ratio (PFSR) in the first trimester of pregnancy, develop normal ranges, and evaluate these markers in abnormal fetuses. METHODS: All measurements were performed on stored images by two operators. Feasibility, interoperator agreement, and prediction intervals were calculated for all measurements...
November 18, 2016: Fetal Diagnosis and Therapy
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