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https://www.readbyqxmd.com/read/27374220/delayed-functional-improvement-after-near-fatal-bleeding-complication-following-endobronchial-valve-therapy-for-emphysema
#1
Sergio Baldi, Francesco Coni, Giorgio Limerutti, Massimo Baccega, Enrico Ruffini, Paolo Solidoro
Endoscopic treatment of emphysema is supported by different methods, including valves, coils and sealants. The mechanism is mainly related to volume reduction of targeted area. Endobronchial valves (EBV) appear the most studied method. In a multicentre randomised study, placement of unidirectional endobronchial valves resulted in a statistically significant functional improvement in the treated cohort compared to the control. Adverse events, occurring post procedure, included COPD exacerbations, haemoptysis, pneumothorax and pneumonia...
2016: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
https://www.readbyqxmd.com/read/27192996/which-long-term-antiplatelet-regimen-for-patients-with-acute-coronary-syndromes
#2
REVIEW
Andrea Picchi, Marco Ferlini, Ugo Limbruno, Stefano De Servi
Dual antiplatelet therapy (DAPT ) is recommended up to 12 months in patients with acute coronary syndromes, but the risk of cardiovascular events in this group of subjects remains high, also in the long-term follow-up. The potential benefit of a prolonged period of DAPT has recently been assessed in three large-volume randomized clinical trials (PEGASUS, DAPT-MI, TRA2P-TIMI 50) but final results are quite difficult to interpret and clear indications for the clinical practice are so far lacking. A direct comparison of the three studies is challenging since relevant differences exist as to clinical features and risk profile of the study populations...
June 2016: Cardiovascular Drugs and Therapy
https://www.readbyqxmd.com/read/27088221/endoscopic-re-opening-of-third-ventriculostomy-case-series-and-review-of-literature
#3
Inês Moreira, Josué Pereira, Joana Oliveira, Sérgio F Salvador, Rui Vaz
OBJECTIVES: Endoscopic third ventriculostomy (ETV) emerged as an effective alternative to shunting devices in patients with obstructive hydrocephalus. When ETV fails, neurosurgeons must choose between applying a shunting device or performing a repeat ETV (re-ETV) and attempt a shunt independent outcome. In this series, clinical, surgical and follow-up data from six patients who underwent a second ETV were reviewed. PATIENTS AND METHODS: Between January 2005 and June 2015, six patients underwent re-ETV, with four being children...
June 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/27057240/intracerebellar-haemorrage-in-a-haemophilia-child
#4
Satya Bhusan Senapati, Sudhansu Sekhar Mishra, Manmath Kumar Dhir, Srikanta Das
Hemophilia A is an inherited, X-linked, recessive disorder caused by deficiency of clotting factor VIII. Intracranial hemorrhage is the leading cause of morbidity and mortality in these patients. Use of factor replacement products and medications had improved outcome in these patients. But in developing countries many such patients are not able to afford factor replacement products. We report a case of traumatic intracerebellar hemorrage in a hemophilia child. This child presented to us as a case of sub-acute intracerebellar hemorrage, he was managed conservatively with six units of fresh frozen plasma transfusion...
April 2016: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/27039247/placenta-previa-with-early-opening-of-the-uterine-isthmus-is-associated-with-high-risk-of-bleeding-during-pregnancy-and-massive-haemorrhage-during-caesarean-delivery
#5
M Goto, J Hasegawa, T Arakaki, H Takita, T Oba, M Nakamura, A Sekizawa
OBJECTIVE: To demonstrate the relationship between the timing of opening of the uterine isthmus and bleeding during pregnancy and caesarean section in patients with placenta previa. METHODS: A prospective observational study was conducted at a single perinatal centre. All patients with placenta previa, diagnosed between 20 and 22 weeks of gestation, who were followed up at the study hospital and underwent caesarean section were enrolled. The condition of the uterine isthmus was examined every 2 weeks...
June 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/26827102/-a-rare-cause-of-haemorrhagic-pleurisy-dissection-of-the-aorta
#6
A Rhanim, L Herrak, H Slimani, L Achachi, M El Ftouh
INTRODUCTION: Haemorragic pleurisy is fairly common. The etiology is dominated by tumors and tuberculosis. The rupture of intra-thoracic vessels into the pleural cavity is a much rarer cause and the diagnosis is often delayed. OBSERVATION: A 77-year-old patient without previously known hypertension was hospitalized for investigation of a fluid density opacity occupying the entire left hemithorax. Thoracentesis revealed a non-coagulable haemorrhagic fluid. A computed tomography scan showed a Stanford type B aortic dissection...
September 2016: Revue des Maladies Respiratoires
https://www.readbyqxmd.com/read/26665233/the-role-of-copeptin-in-patients-with-subarachnoid-haemorrage
#7
Athanassios Zissimopoulos, Theodosia Vogiatzaki, Fotini Babatsikou, Marion Velissaratou, Lukia Baloka, Evangelos Karathanos, Anastasia Pistola, Xristos Christofis, Xristos Iatrou
OBJECTIVE: Subarachnoid haemorrhage is responsible to a great extend for the death rate of patients who are hospitalised in intensive care units (ICU) with haemorrhage. The early detection of its severity plays an important role for the resulting health of the patients. Neurohormone Copeptin is the C-end of pro-arginine vasopressin in plasma has been used as a prognostic marker in a number of various illnesses (acute myocardial infarction, heart and renal failure, acute dyspnoea, intracerebral and subarachnoid haemorrhage, ischaemic stroke, liver cirrhosis, acute pancreatitis)...
September 2015: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/25551322/pharmacogenetics-based-warfarin-dosing-algorithm-decreases-time-to-stable-anticoagulation-and-the-risk-of-major-hemorrhage-an-updated-meta-analysis-of-randomized-controlled-trials
#8
Zhi-Quan Wang, Rui Zhang, Peng-Pai Zhang, Xiao-Hong Liu, Jian Sun, Jun Wang, Xiang-Fei Feng, Qiu-Fen Lu, Yi-Gang Li
Warfarin is yet the most widely used oral anticoagulant for thromboembolic diseases, despite the recently emerged novel anticoagulants. However, difficulty in maintaining stable dose within the therapeutic range and subsequent serious adverse effects markedly limited its use in clinical practice. Pharmacogenetics-based warfarin dosing algorithm is a recently emerged strategy to predict the initial and maintaining dose of warfarin. However, whether this algorithm is superior over conventional clinically guided dosing algorithm remains controversial...
April 2015: Journal of Cardiovascular Pharmacology
https://www.readbyqxmd.com/read/25508486/uterine-packing-in-the-management-of-complete-placenta-praeuvia
#9
I Okafori, E O Ugwu, N Obis, E E Nwogu-Ikojo
BACKGROUND: Complete (type 4) placenta praevia is a major cause of haemorrhage in Obstetrics. Uterine packing is an effective but underutilized life-saving intervention in situation of uncontrolled haemorrahage due to major placenta praevia. OBJECTIVES: To reappraise the effectiveness of uterine packing in the management of complete placenta praevia in order to popularize the practice. METHODS: Seven case series of complete placenta praevia were managed with uterine packing in Enugu, Nigeria between January 2, 2012 and February 28, 2013...
October 2014: Nigerian Journal of Medicine: Journal of the National Association of Resident Doctors of Nigeria
https://www.readbyqxmd.com/read/25470859/uterine-packing-in-the-management-of-complete-placenta-praeuvia
#10
I Okafori, E O Ugwu, N Obis, E E Nwogu-Ikojo
BACKGROUND: Complete (type 4) placenta praevia is a major cause of haemorrhage in Obstetrics. Uterine packing is an effective but underutilized life-saving intervention in situation of uncontrolled haemorrahage due to major placenta praevia. OBJECTIVES: To reappraise the effectiveness of uterine packing in the management of complete placenta praevia in order to popularize the practice. METHODS: Seven case series of complete placenta praevia were managed with uterine packing in Enugu, Nigeria between January 2, 2012 and February 28, 2013...
October 2014: Nigerian Journal of Medicine: Journal of the National Association of Resident Doctors of Nigeria
https://www.readbyqxmd.com/read/24628275/hepatic-artery-complications-following-liver-transplantation-does-preoperative-chemoembolization-impact-the-postoperative-course
#11
Fabrizio Panaro, Jeanne Ramos, Benoit Gallix, Grégoire Mercier, Astrid Herrero, Halidou Niampa, Georges-Philippe Pageaux, Francis Navarro
BACKGROUND: Transarterial chemoembolization (TACE) in patients with hepatocellular carcinoma (HCC) may cause damage to the hepatic artery (HA) and impact the postoperative course of the liver transplantation (LT). We aim to describe the relationship between preoperative TACE and the occurrence of histological and radiological hepatic artery complications (HAC). METHODS: All cirrhotic patients with HCC undergoing LT between January 2009 and October 2012 were included and divided in two groups: TACE (group 1) and No TACE (group 2)...
May 2014: Clinical Transplantation
https://www.readbyqxmd.com/read/24193568/-results-of-surgical-treatment-of-metastases-of-renal-carcinomas-in-65-operated-cases
#12
P Simon, M Katzner, P Montes, P Gleyze, S R Babin
Several reports have assessed that the prognosis of metastatic renal cell carcinoma was better if patient's general condition was good, if primary tumor had been resected, if the time between nephrectomy and metastasis was long, if metastases are only pulmonary and bone marrow was not involved. The bone metastases of renal cell cancer have a bad reputation because of their haemorragic caracteristics and their resistance to radiotherapy.In the Orthopaedic and Traumatologic Department of the University hospital in Strasbourg, the authors had operated on 65 metastatic renal cell cancers...
February 1996: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/24187785/-fever-skin-rash-and-blood-bullae-of-the-ears-in-a-middle-aged-woman
#13
Jaana Syrjänen, Mirja Puolakkainen, Asko Järvinen
A healthcare worker sought medical advice after four days of fever, muscle pains, occipital headache and blocked ears, and was diagnosed with a high CRP level and blood bullae in the outer ear canal. In addition, skin rash appeared during hospital care, and the fever did not seem to go down upon treatment with broad-spectrum antibiotics, during which the CRP rose to a level of 413 mg/L at the highest. Haemorragic bullous otisis was confirmed diagnosis caused by Mycoplasma Pneumoniae.
2013: Duodecim; Lääketieteellinen Aikakauskirja
https://www.readbyqxmd.com/read/24161296/-peripartum-period-and-hemophilia-carriers
#14
A Bonnet, Y Chevalier, G Wallon, C Huissoud, F Aubrun
Women who are carriers for hemophilia are usually considered as safe carriers. However, they can present hemorragic symptoms associated with low factor VIII or IX levels. During pregancy, factor VIII increases whereas factor IX does not. The peripartum period is at risk of increased bleeding in these women. Here are presented reports of clinical data concerning two hemophilia carriers with low factor VIII or IX (30-40%) during the peripartum period. They received remifentanil and ketamine for labor pain management because of contraindication of epidural and spinal analgesia...
November 2013: Annales Françaises D'anesthèsie et de Rèanimation
https://www.readbyqxmd.com/read/23920228/phytochemistry-and-pharmacognosy-of-the-genus-acronychia
#15
REVIEW
Francesco Epifano, Serena Fiorito, Salvatore Genovese
The genus Acronychia (Rutaceae) comprise 44 species, most of which are represented by shrubs and small trees, distributed in a wide geographical area of South-Eastern Asia comprising China, India, Malaysia, Indonesia, Australia, and the islands of the western Pacific Ocean. Most of the species of the genus Acronychia have been used for centuries as natural remedies in the ethnomedical traditions of indigenous populations as anti-microbial, anti-fungal, anti-spasmodic, stomachic, anti-pyretic, and anti-haemorragic agent...
November 2013: Phytochemistry
https://www.readbyqxmd.com/read/23832481/-the-acute-renal-and-cerebral-toxicity-of-lithium-a-cerebro-renal-syndrome-a-case-report
#16
M Prencipe, A Cicchella, A Del Giudice, A Di Giorgio, A Scarlatella, M Vergura, F Aucella
This descriptive report describes the case of a 50 year-old woman with bipolar disorder, whose maintenance therapy comprised risperidone, sodium valproato and lithium carbonate without any past occurrence of toxicity. Her past medical history was significant for hypertension, cardiopathy and obesity. She presented with a 1-week history of fever, increasing confusion and slurred speech. At presentation, the patient was somnolent. Laboratory investigations revealed a serum creatinine of 3,6 mg/dl, BUN 45 mg/dl serum lithium 3,0 mEq/L with polyuria defined as more than 3 litres a day...
May 2013: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://www.readbyqxmd.com/read/23830043/-thrice-weekly-warfarin-administration-results-in-12-hemodialysis-patients
#17
Jean-Michel Poux, Karim Dardim, Quang Thu Nguyen, Graziella Arnaud, Marie-Pierre Nord Rouby, Maria Manescu
We report our experience of thrice-weekly warfarin administration, at the end of the dialysis session, in 12 patients (average age: 79 ± 5 years). In 10 cases, indication for anticoagulation therapy was atrial fibrillation, in one case a mechanical heart valve, in another case axillo femoral bypass. The International Normalized Ratio (INR) therapeutic goal was between 2 and 3, except for the patient with a mechanical aortic heart valve, whose goal was between 2.5 and 3.5. The INR was determined during the first dialysis session of the week...
November 2013: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/23178136/-therapeutic-strategies-for-escherichia-coli-neonatal-meningitis
#18
X Durrmeyer, R Cohen, E Bingen, Y Aujard
Outcome of early and late onset E. coli neonatal meningitis is poor with 12% (term infant) to 18% (premature infant) mortality rates. Early complications are cerebral abscesses, ventriculitis and ischemo-haemorragic cerebral lesions. Long term sequelae, particularly neurosensorial [14-17%] and neurodevelopmental [10-17%] are frequent. Delayed or unadapted antibiotic treatment is associated with an excess of complications. Main risk factors are hemodynamic failure, apnea, seizures, hypoglycorachia and abnormal EEG...
November 2012: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/23119776/middle-ear-malignancy-masquerading-as-csom
#19
S Kumar K, M Venugopal, S Rajan
Malignant transformation in middle ear cleft is an extremely rare phenomenon, squamous cell carcinoma being the most likely neoplasm. Classical hallmarks of otologic haemorrage, facial palsy and inner ear damage may not be evident in a few cases though a long history of CSOM provides accolade. We present a young male operated upon for a seemingly benign otologic supprative illness where an extensively destructive malignant disease with intracranial extension was unveiled.
April 2001: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/22953652/hereditary-haemorragic-teleangectasia-and-pregnancy-case-report
#20
B Della Vella, V Unfer, C Nania, M L Borgia, A Saraceno, M Minozzi
We report an uncommon case of a 38-years-old pregnant woman affected by HHT (Hereditary haemorrhagic telangiectasia; Osler-Weber-Rendu syndrome) who underwent to a caesarean section (CS) without any complication. The patient at 36th weeks+1 day pregnancy referred to the Emergency Obstetric Unit due to a intercostals pain on left side. On third day after admission the woman started travailing and physicians decided to perform the CS. Considering that no AVMs was found at MRI, a continuous spinal anaesthesia was planned...
July 2012: European Review for Medical and Pharmacological Sciences
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