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https://www.readbyqxmd.com/read/28934295/the-lithic-assemblages-of-donggutuo-nihewan-basin-knapping-skills-of-early-pleistocene-hominins-in-north-china
#1
Shi-Xia Yang, Michael D Petraglia, Ya-Mei Hou, Jian-Ping Yue, Cheng-Long Deng, Ri-Xiang Zhu
Donggutuo (DGT) is one of the richest archaeological localities in the Nihewan Basin of North China, thereby providing key information about the technological behaviours of early hominins in eastern Asia. Although DGT has been subject of multiple excavations and technological studies over the past several decades, few detailed studies on the lithic assemblages have been published. Here we summarize and describe the DGT lithic assemblages, examining stone tool reduction methods and technological skills. DGT dates to ca...
2017: PloS One
https://www.readbyqxmd.com/read/28934152/an-authentication-and-key-management-mechanism-for-resource-constrained-devices-in-ieee-802-11-based-iot-access-networks
#2
Ki-Wook Kim, Youn-Hee Han, Sung-Gi Min
Many Internet of Things (IoT) services utilize an IoT access network to connect small devices with remote servers. They can share an access network with standard communication technology, such as IEEE 802.11ah. However, an authentication and key management (AKM) mechanism for resource constrained IoT devices using IEEE 802.11ah has not been proposed as yet. We therefore propose a new AKM mechanism for an IoT access network, which is based on IEEE 802.11 key management with the IEEE 802.1X authentication mechanism...
September 21, 2017: Sensors
https://www.readbyqxmd.com/read/28934045/the-ethics-of-big-data-and-nursing-science
#3
Constance L Milton
Big data is a scientific, social, and technological trend referring to the process and size of datasets available for analysis. Ethical implications arise as healthcare disciplines, including nursing, struggle over questions of informed consent, privacy, ownership of data, and its possible use in epistemology. The author offers straight-thinking possibilities for the use of big data in nursing science.
October 2017: Nursing Science Quarterly
https://www.readbyqxmd.com/read/28933506/the-international-classification-of-functioning-disability-and-health-icf-in-electronic-health-records-a-systematic-literature-review
#4
Roxanne Maritz, Dominik Aronsky, Birgit Prodinger
BACKGROUND: The International Classification of Functioning, Disability and Health (ICF) is the World Health Organization's standard for describing health and health-related states. Examples of how the ICF has been used in Electronic Health Records (EHRs) have not been systematically summarized and described yet. OBJECTIVES: To provide a systematic review of peer-reviewed literature about the ICF's use in EHRs, including related challenges and benefits. METHODS: Peer-reviewed literature, published between January 2001 and July 2015 was retrieved from Medline(®), CINAHL(®), Scopus(®), and ProQuest(®) Social Sciences using search terms related to ICF and EHR concepts...
September 20, 2017: Applied Clinical Informatics
https://www.readbyqxmd.com/read/28933478/natural-product-modulators-of-human-sensations-and-mood-molecular-mechanisms-and-therapeutic-potential
#5
REVIEW
Tomáš Pluskal, Jing-Ke Weng
Humans perceive physical information about the surrounding environment through their senses. This physical information is registered by a collection of highly evolved and finely tuned molecular sensory receptors. A multitude of bioactive, structurally diverse ligands have evolved in nature that bind these molecular receptors. The complex, dynamic interactions between the ligands and the receptors lead to changes in our sensory perception or mood. Here, we review our current knowledge of natural products and their derived analogues that interact specifically with human G protein-coupled receptors, ion channels, and nuclear hormone receptors to modulate the sensations of taste, smell, temperature, pain, and itch, as well as mood and its associated behaviour...
September 21, 2017: Chemical Society Reviews
https://www.readbyqxmd.com/read/28933439/3d-printing-of-high-strength-aluminium-alloys
#6
John H Martin, Brennan D Yahata, Jacob M Hundley, Justin A Mayer, Tobias A Schaedler, Tresa M Pollock
Metal-based additive manufacturing, or three-dimensional (3D) printing, is a potentially disruptive technology across multiple industries, including the aerospace, biomedical and automotive industries. Building up metal components layer by layer increases design freedom and manufacturing flexibility, thereby enabling complex geometries, increased product customization and shorter time to market, while eliminating traditional economy-of-scale constraints. However, currently only a few alloys, the most relevant being AlSi10Mg, TiAl6V4, CoCr and Inconel 718, can be reliably printed; the vast majority of the more than 5,500 alloys in use today cannot be additively manufactured because the melting and solidification dynamics during the printing process lead to intolerable microstructures with large columnar grains and periodic cracks...
September 20, 2017: Nature
https://www.readbyqxmd.com/read/28933102/-resources-industrialization-channels-and-strategies-of-active-polysaccharide-from-lycii-fructus-based-on-analysis-of-domestic-and-foreign-intellectual-properties
#7
REVIEW
Fang Zhang, Sheng Guo, Da-Wei Qian, Xia Zhang, Xiao-Chun Yang, Yong-Jing Li, Jin-Ao Duan
Lycii Fructus is a traditional medicinal and edible herb, with the function of liver and kidney nourishing, blood and eyesight replenishing. As the most important active substance in the fruits of Lycium barbarum, Lycium barbarum polysaccharides (LBP) have been demonstrated to play multiple pharmacological activities, with broad prospects for development and utilization. Based on the comprehensive deep analysis of global LBP patent output, the current patent LBP features were explored from the perspective of development trend, technology field distribution, time dimension, technology life curve and patent applicant...
December 2016: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28933076/-strategies-of-elucidation-of-biosynthetic-pathways-of-natural-products
#8
Li-Qiu Zou, Xue-Jun Kuang, Chao Sun, Shi-Lin Chen
Elucidation of the biosynthetic pathways of natural products is not only the major goal of herb genomics, but also the solid foundation of synthetic biology of natural products. Here, this paper reviewed recent advance in this field and put forward strategies to elucidate the biosynthetic pathway of natural products. Firstly, a proposed biosynthetic pathway should be set up based on well-known knowledge about chemical reactions and information on the identified compounds, as well as studies with isotope tracer...
November 2016: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28932780/data-on-european-non-residential-buildings
#9
Delia D'Agostino, Barbara Cuniberti, Paolo Bertoldi
This data article relates to the research paper Energy consumption and efficiency technology measures in European non-residential buildings (D'Agostino et al., 2017) [1]. The reported data have been collected in the framework of the Green Building Programme that ran from 2006 to 2014. The project has encouraged the adoption of efficiency measures to boost energy savings in European non-residential buildings. Data focus on the one-thousand buildings that joined the Programme allowing to save around 985 GWh/year...
October 2017: Data in Brief
https://www.readbyqxmd.com/read/28932779/technoeconomic-assumptions-adopted-for-the-development-of-a-long-term-electricity-supply-model-for-cyprus
#10
Constantinos Taliotis, Emanuele Taibi, Mark Howells, Holger Rogner, Morgan Bazilian, Manuel Welsch
The generation mix of Cyprus has been dominated by oil products for decades. In order to conform with European Union and international legislation, a transformation of the supply system is called for. Energy system models can facilitate energy planning into the future, but a large volume of data is required to populate such models. The present data article provides information on key modelling assumptions and input data adopted with the aim of representing the electricity supply system of Cyprus in a separate research article...
October 2017: Data in Brief
https://www.readbyqxmd.com/read/28932740/tapping-the-vast-potential-of-the-data-deluge-in-small-scale-food-animal-production-businesses-challenges-to-near-real-time-data-analysis-and-interpretation
#11
Flavie Vial, Andrew Tedder
Food-animal production businesses are part of a data-driven ecosystem shaped by stringent requirements for traceability along the value chain and the expanding capabilities of connected products. Within this sector, the generation of animal health intelligence, in particular, in terms of antimicrobial usage, is hindered by the lack of a centralized framework for data storage and usage. In this Perspective, we delimit the 11 processes required for evidence-based decisions and explore processes 3 (digital data acquisition) to 10 (communication to decision-makers) in more depth...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/28932623/proteomics-technique-opens-new-frontiers-in-mobilome-research
#12
COMMENT
Andrew D Davidson, David A Matthews, Kevin Maringer
A large proportion of the genome of most eukaryotic organisms consists of highly repetitive mobile genetic elements. The sum of these elements is called the "mobilome," which in eukaryotes is made up mostly of transposons. Transposable elements contribute to disease, evolution, and normal physiology by mediating genetic rearrangement, and through the "domestication" of transposon proteins for cellular functions. Although 'omics studies of mobilome genomes and transcriptomes are common, technical challenges have hampered high-throughput global proteomics analyses of transposons...
2017: Mobile Genetic Elements
https://www.readbyqxmd.com/read/28932243/sensitive-wavelengths-selection-in-identification-of-ophiopogon-japonicus-based-on-near-infrared-hyperspectral-imaging-technology
#13
Zhengyan Xia, Chu Zhang, Haiyong Weng, Pengcheng Nie, Yong He
Hyperspectral imaging (HSI) technology has increasingly been applied as an analytical tool in fields of agricultural, food, and Traditional Chinese Medicine over the past few years. The HSI spectrum of a sample is typically achieved by a spectroradiometer at hundreds of wavelengths. In recent years, considerable effort has been made towards identifying wavelengths (variables) that contribute useful information. Wavelengths selection is a critical step in data analysis for Raman, NIRS, or HSI spectroscopy. In this study, the performances of 10 different wavelength selection methods for the discrimination of Ophiopogon japonicus of different origin were compared...
2017: International Journal of Analytical Chemistry
https://www.readbyqxmd.com/read/28931430/global-proteomic-profiling-of-yersinia-ruckeri-strains
#14
Gokhlesh Kumar, Karin Hummel, Timothy J Welch, Ebrahim Razzazi-Fazeli, Mansour El-Matbouli
Yersinia ruckeri is the causative agent of enteric redmouth disease (ERM) of salmonids. There is little information regarding the proteomics of Y. ruckeri. Herein, we perform whole protein identification and quantification of biotype 1 and biotype 2 strains of Y. ruckeri grown under standard culture conditions using a shotgun proteomic approach. Proteins were extracted, digested and peptides were separated by a nano liquid chromatography system and analyzed with a high-resolution hybrid triple quadrupole time of flight mass spectrometer coupled via a nano ESI interface...
September 20, 2017: Veterinary Research
https://www.readbyqxmd.com/read/28931422/pibas-fedsparql-a-web-based-platform-for-integration-and-exploration-of-bioinformatics-datasets
#15
Marija Djokic-Petrovic, Vladimir Cvjetkovic, Jeremy Yang, Marko Zivanovic, David J Wild
BACKGROUND: There are a huge variety of data sources relevant to chemical, biological and pharmacological research, but these data sources are highly siloed and cannot be queried together in a straightforward way. Semantic technologies offer the ability to create links and mappings across datasets and manage them as a single, linked network so that searching can be carried out across datasets, independently of the source. We have developed an application called PIBAS FedSPARQL that uses semantic technologies to allow researchers to carry out such searching across a vast array of data sources...
September 20, 2017: Journal of Biomedical Semantics
https://www.readbyqxmd.com/read/28931409/clinical-review-of-24-35%C3%A2-year-olds-conceived-with-and-without-in-vitro-fertilization-study-protocol
#16
Sharon Lewis, Joanne Kennedy, David Burgner, Robert McLachlan, Sarath Ranganathan, Karin Hammarberg, Richard Saffery, David J Amor, Michael M H Cheung, Lex W Doyle, Markus Juonala, Susan Donath, John McBain, Jane Halliday
BACKGROUND: Children conceived by assisted reproductive technologies (ART) currently comprise 4% of Australian births. The manipulation of biological parameters related to fertilization and implantation are integral to successful ART but potentially pose a risk to the longer-term health of the offspring. There is consensus that many common adult health problems (particularly cardiovascular, metabolic and respiratory conditions) have their origins in early life, possibly before birth, and that risk trajectories track through childhood until clinical disease manifests in adulthood...
September 20, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28931377/the-rehabilitation-enhancing-aging-through-connected-health-reach-study-study-protocol-for-a-quasi-experimental-clinical-trial
#17
Meng Ni, Lorna G Brown, Danielle Lawler, Terry D Ellis, Tamara Deangelis, Nancy K Latham, Jennifer Perloff, Steve J Atlas, Sanja Percac-Lima, Jonathan F Bean
BACKGROUND: Mobility limitations among older adults increase the risk for disability and healthcare utilization. Rehabilitative care is identified as the most efficacious treatment for maintaining physical function. However, there is insufficient evidence identifying a healthcare model that targets prevention of mobility decline among older adults. The objective of this study is to evaluate the preliminary effectiveness of a physical therapy program, augmented with mobile tele-health technology, on mobility function and healthcare utilization among older adults...
September 20, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28931315/the-liver-toxicity-knowledge-base-lktb-and-drug-induced-liver-injury-dili-classification-for-assessment-of-human-liver-injury
#18
Shraddha Thakkar, Weida Tong, Minjun Chen, Hong Fang, Zhichao Liu, Ruth Roberts
Drug-induced liver injury (DILI) is challenging drug development, clinical practice and regulation. The Liver Toxicity Knowledge Base (LTKB) provides essential data for DILI study. Areas Covered: The LTKB provided various types of data that can be used to assess and predict DILI. Among much information available, several reference drug lists with annotated human DILI risk are of important. The LTKB DILI classification data include DILI severity concern determined by the FDA drug labeling, DILI severity score from the NIH LiverTox database, and other DILI classification schemes from the literature...
September 21, 2017: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28931022/examining-accident-reports-involving-autonomous-vehicles-in-california
#19
Francesca M Favarò, Nazanin Nader, Sky O Eurich, Michelle Tripp, Naresh Varadaraju
Autonomous Vehicle technology is quickly expanding its market and has found in Silicon Valley, California, a strong foothold for preliminary testing on public roads. In an effort to promote safety and transparency to consumers, the California Department of Motor Vehicles has mandated that reports of accidents involving autonomous vehicles be drafted and made available to the public. The present work shows an in-depth analysis of the accident reports filed by different manufacturers that are testing autonomous vehicles in California (testing data from September 2014 to March 2017)...
2017: PloS One
https://www.readbyqxmd.com/read/28930796/navigating-t-cell-immunometabolism-in-transplantation
#20
Naoki Tanimine, Laurence A Turka, Bhavana Priyadharshini
Recently, a new discipline termed "immunometabolism" has transformed the field of immunology. It encompasses the study of the intrinsic metabolic pathways of different immune subsets and their impact on cellular fate and function. For instance, broadly speaking, pro-inflammatory cells depend upon glycolysis and glutamine oxidation while cells involved in anti-inflammatory response such as Foxp3+ regulatory T cells (Tregs) utilize predominantly fatty acid oxidation. However, while a useful paradigm, this actually is a reductionist view and the engagement of these metabolic pathways is not mutually exclusive between these subsets...
September 19, 2017: Transplantation
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