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https://www.readbyqxmd.com/read/28642801/differences-in-the-tongue-features-of-primary-dysmenorrhea-patients-and-controls-over-a-normal-menstrual-cycle
#1
Jihye Kim, Haebeom Lee, Hyunho Kim, Jong Yeol Kim, Keun Ho Kim
BACKGROUND: The aims of this study were to investigate the relationships between tongue features and the existence of menstrual pain and to provide basic information regarding the changes in tongue features during a menstrual cycle. METHODS: This study was conducted at the Kyung Hee University Medical Center. Forty-eight eligible participants aged 20 to 29 years were enrolled and assigned to two groups according to their visual analogue scale (VAS) scores. Group A included 24 females suffering from primary dysmenorrhea (PD) caused by qi stagnation and blood stasis syndrome with VAS ≥ 4...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28634864/diagnostic-indicators-for-blood-stasis-syndrome-patients-with-gynaecological-diseases
#2
Jeeyoun Jung, Mi Mi Ko, Myeong Soo Lee, So Min Lee, Ju Ah Lee
OBJECTIVE: To investigate the important diagnostic indicators for blood stasis syndrome (BSS) in patients of childbearing age with gynaecological diseases. METHODS: A partial least squared-discriminant analysis (PLS-DA) were applied to BSS symptoms data of patients with gynaecological diseases, and the diagnostic indicators used by doctors of Korean medicine (DKMs) among BSS patients with gynaecological diseases were also investigated. RESULTS: A total of 103 patients of childbearing age with gynaecological diseases and 40 healthy controls were enrolled...
June 20, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28620545/cardiovascular-risk-factors-among-women-with-self-reported-infertility
#3
Shruthi Mahalingaiah, Fangui Sun, J Jojo Cheng, Erika T Chow, Kathryn L Lunetta, Joanne M Murabito
BACKGROUND: Amongst women with certain types of ovulatory disorder infertility, the studies are conflicting whether there is an increased risk of long-term cardiovascular disease risk. This paper evaluates the associations of several CVD risk factors among Framingham women with self-reported infertility. METHODS: Women who completed the Framingham Heart Study Third Generation and Omni Cohort 2 Exam 2 (2008-2011), and reported on past history of infertility and current cardiovascular disease status were included in this cross-sectional study...
2017: Fertility Research and Practice
https://www.readbyqxmd.com/read/28616051/omega-3-supplementation-effects-on-polycystic-ovary-syndrome-symptoms-and-metabolic-syndrome
#4
Behnaz Khani, Farahnaz Mardanian, Sajadeh Jafari Fesharaki
BACKGROUND: Polycystic ovary syndrome (PCOS) is the most common female endocrine disorder with unknown etiology and with different complications. The aim of this study was to evaluate the effect of omega-3 supplementation on PCOS symptoms and metabolic syndrome. MATERIALS AND METHODS: This double-blind clinical trial was performed in 2015 in Alzahra and Shahid Beheshti Hospitals, Isfahan, Iran, on 88 patients with PCOS. Intervention group took omega-3 supplements with dose of 2 g/day for 6 months (two capsules), but control group received two olive oil capsules...
2017: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/28605652/screening-and-confirmation-of-microrna-markers-for-distinguishing-between-menstrual-and-peripheral-blood
#5
Zhilong Li, Peng Bai, Duo Peng, Hui Wang, Yadong Guo, Youjing Jiang, Wang He, Huan Tian, Yu Yang, Yuan Huang, Bing Long, Weibo Liang, Lin Zhang
The identification of menstrual blood (MB) and peripheral blood (PB) left at a crime scene is crucial for crime reconstruction, especially in sexual assaults. MicroRNAs (miRNAs), a class of non-protein coding molecules, have been demonstrated to be a viable tool for body fluid identification in forensic casework. Several groups have searched for miRNAs that are specific to different body fluids. Blood has been studied the most extensively. However, menstrual blood was only involved in five studies, and the results confirming the presence of specific miRNAs could not be reproduced in other studies...
June 3, 2017: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/28597715/effect-of-menstrual-phase-on-the-surgical-treatment-of-ovarian-cysts
#6
Taejong Song, Mi Kyoung Kim, Mi-La Kim, Yong Wook Jung, Bo Seong Yun, Seok Ju Seong
This study aimed to determine whether the menstrual cycle affects operative bleeding and postoperative ovarian reserve in patients undergoing laparoscopic ovarian cystectomy. A total of 155 patients who had undergone laparoscopic ovarian cystectomy were classified into the follicular phase (n = 84) and luteal phase (n = 71) of the menstrual cycle. The primary outcome measures were operative blood loss and the rate of decline in ovarian reserve, as calculated by measuring serial serum anti-Müllerian hormone (AMH) levels preoperatively and 3 months postoperatively...
June 9, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28597496/elevated-anti-mullerian-hormone-in-lean-women-may-not-indicate-polycystic-ovarian-syndrome
#7
Rachel A Bradbury, Paul Lee, Howard C Smith
BACKGROUND: Polycystic ovarian syndrome (PCOS) is a heterogeneous disorder with clinical features shared with functional hypogonadotrophic hypogonadism (FHH). AIM: To investigate the usefulness of an elevated (>40 pmol/L) anti-Mullerian hormone (AMH) in identifying PCOS and distinguishing PCOS from FHH. MATERIALS AND METHODS: 141 patients with an elevated AMH and body mass index either <20 kg/m(2) (lean) or >30 kg/m(2) (obese) were selected and three subgroups analysed - obese, lean, lean with suspected FHH...
June 9, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28596097/menstrual-cycle-vocal-performance-and-laryngeal-vascular-appearance-an-observational-study-on-17-subjects
#8
Hagit Shoffel-Havakuk, Narin N Carmel-Neiderman, Doron Halperin, Yael Shapira Galitz, Dan Levin, Yaara Haimovich, Oded Cohen, Jean Abitbol, Yonatan Lahav
OBJECTIVE: To assess the anatomical and functional features of the vocal folds during different phases of the female menstrual cycle. METHODS: An observational study of 17 healthy fertile female volunteers not using hormonal contraception was carried out. Each volunteer underwent two examinations: first, during the early days of the menstrual cycle when progesterone levels are low (p-depletion), and second, during premenstruation when progesterone levels are high (p-peak)...
June 5, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28593921/hyperandrogenism-in-adolescent-girls-relationship-with-the-somatotrophic-axis
#9
María Isabel Hernandez, Patricia López, Ximena Gaete, Claudio Villarroel, Gabriel Cavada, Alejandra Avila, German Iñiguez, Fernando Cassorla
BACKGROUND: During puberty there is a physiologic increase in adrenal and ovarian androgens. It has been suggested that the somatotrophic axis may be related to the development of hyperandrogenism and anovulation in non-obese adult women with polycystic ovarian syndrome (PCOS). The objective of the study was to investigate whether ovarian androgen secretion in young postmenarchal girls is related to the function of their somatotropic axis. METHODS: This was a cross-sectional study of adolescent girls...
May 1, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/28588205/human-uterine-lymphocytes-acquire-a-more-experienced-and-tolerogenic-phenotype-during-pregnancy
#10
Dorien Feyaerts, Marilen Benner, Bram van Cranenbroek, Olivier W H van der Heijden, Irma Joosten, Renate G van der Molen
Pregnancy requires a delicate immune balance that nurtures the allogeneic fetus, while maintaining reactivity against pathogens. Despite increasing knowledge, data is lacking on the transition of pre-pregnancy endometrial lymphocytes to a pregnancy state. Here, we immunophenotyped lymphocytes from endometrium (MMC), term decidua parietalis (DPMC), and PBMC for direct comparison. We found that the immune cell composition of MMC and DPMC clearly differ from each other, with less NK-cells, and more NKT-cells and T-cells in DPMC...
June 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28587393/effects-of-hypoxia-on-differentiation-of-menstrual-blood-stromal-stem-cells-towards-tenogenic-cells-in-a-co-culture-system-with-achilles-tendon-cells
#11
Yijing Zheng, Yifei Zhou, Xiaolei Zhang, Yuemiao Chen, Xuhao Zheng, Tao Cheng, Chaonan Wang, Xuqi Hu, Jianjun Hong
Achilles tendons have a very poor capacity for intrinsic regeneration. The cell-based treatment strategy for Achilles tendinitis includes the application of mesenchymal stem cells (MSCs), which have high proliferative and multipotent differentiation ability, and is a promising approach. The aim of the present study was to explore the tenogenic potential of human menstrual blood stromal stem cells (MenSCs) in a co-culture system and to compare the tenogenic capability under normoxic and hypoxic conditions. MenSCs were co-cultured indirectly with Achilles tendon cells in a Transwell co-culture system for 1, 2, or 3 weeks in two different concentrations of oxygen (20 and 2% O2), whereas the control contained only MenSCs...
June 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28584969/the-effect-of-melatonin-on-gene-expression-of-calcitonin-gene-related-peptide-and-some-proinflammatory-mediators-in-patients-with-pure-menstrual-migraine
#12
Mohammad Ansari, Azam Karkhaneh, Asma Kheirollahi, Solaleh Emamgholipour, Mohammad Hessam Rafiee
The neuropeptide calcitonin gene-related peptide (CGRP), a potent vasoactive and a marker of trigeminal inflammation, has been considered as an important mediator in various types of migraine such as pure menstrual migraine. Earlier studies have shown that CGRP can modulate the synthesis and release of other inflammatory factor including nitric oxide (NO) and interleukin-1beta (IL-1β) from trigeminal ganglion glial cells. Exogenous melatonin protects the tissues from inflammatory damages. The goal of this study was to determine the anti-inflammatory effects of melatonin on the CGRP expression, inducible nitric oxide synthase (iNOS) activity, NO, and IL-1β release in cultured peripheral blood mononuclear cells (PBMCs) from pure menstrual migraine patients and healthy subjects...
June 5, 2017: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/28579415/elagolix-for-the-management-of-heavy-menstrual-bleeding-associated-with-uterine-fibroids-results-from-a-phase-2a-proof-of-concept-study
#13
David F Archer, Elizabeth A Stewart, Rita I Jain, Robert A Feldman, Andrea S Lukes, Janine D North, Ahmed M Soliman, Jingjing Gao, Juki W Ng, Kristof Chwalisz
OBJECTIVE: To evaluate the safety and efficacy of elagolix vs. placebo and elagolix with low-dose E2/progestogen add-back therapy. DESIGN: Proof-of-concept, dose-ranging, multiple-cohort study. SETTING: Forty-five US clinics. PATIENT(S): Premenopausal women with fibroids and heavy menstrual bleeding (menstrual blood loss [MBL] >80 mL per cycle). INTERVENTION(S): Three months' treatment with elagolix alone: 100 mg twice daily (BID), 200 mg BID, 300 mg BID, 400 mg once daily (QD), or 600 mg QD (all but the 600 mg QD arm were placebo controlled); or elagolix plus add-back therapy: 200 mg BID plus continuous low-dose E2 0...
June 1, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28579353/in%C3%A2-vitro-differentiation-of-menstrual-blood-stem-cells-into-keratinocytes-a-potential-approach-for-management-of-wound-healing
#14
Maryam Akhavan-Tavakoli, Maryam Fard, Sayeh Khanjani, Sona Zare, Haleh Edalatkhah, Davood Mehrabani, Amir-Hassan Zarnani, Reza Shirazi, Somaieh Kazemnejad
The skin wounds caused by insults should be treated immediately to restore the functions and integrity. Recent studies suggest that stem cells-based therapies may be applicable in wound healing. Newly defined menstrual blood-derived stem cells (MenSCs) show high rate of cell proliferation and trans-differentiation potency to various cell types. However, MenSCs potential to generate keratinocyte for future therapeutic use of skin lesions has been remained to investigate. We cultivated MenSCs in the presence of isolated foreskin derived-keratinocytes using an indirect co-culture system and evaluated efficiency of this protocol to generate keratinocytes using immunofluorescent staining and Real Time PCR technique...
June 1, 2017: Biologicals: Journal of the International Association of Biological Standardization
https://www.readbyqxmd.com/read/28567195/abdominal-myomectomy-a-retrospective-review-of-determinants-and-outcomes-of-complications-at-the-university-of-ilorin-teaching-hospital-ilorin-nigeria
#15
Kikelomo T Adesina, Beatrice O Owolabi, Hadijat O Raji, Adebunmi O Olarinoye
BACKGROUND: The aim of this study was to describe the pattern, outcomes, and determinants of perioperative complications of abdominal myomectomy at the University of Ilorin Teaching Hospital, Ilorin, Nigeria. METHODS: This was a retrospective review of cases of abdominal myomectomy between January 2010 and December 2013. Data were obtained from ward and operating theatre case records and analysed using SPSS version 20. The continuous variables were analysed with Student's t-test...
March 2017: Malawi Medical Journal: the Journal of Medical Association of Malawi
https://www.readbyqxmd.com/read/28546821/evaluation-of-neutrophil-lymphocyte-ratio-platelet-lymphocyte-ratio-and-red-blood-cell-distribution-width-platelet-ratio-for-diagnosis-of-premature-ovarian-insufficiency
#16
Gulsah Ilhan, Fatma Ferda Verit Atmaca, Esra Altan, Ali Galip Zebitay, Hamdullah Sozen, Hurkan Akyol, Meryem Kurek Eken
Objective: To evaluate whether systemic inflammatory markers (neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR) and red blood cell distribution width (RDW) to platelet ratio (RPR)) can be used as reliable markers for the diagnosis of premature ovarian insufficiency (POI) and to determine if there is a relationship between these markers and follicle stimulating hormone (FSH), Anti-Müllerian Hormone (AMH) levels. Materials and methods: Written and electronic medical records were reviewed using searches for diagnoses with the terms of 'premature ovarian failure', 'premature ovarian insufficiency'...
December 2016: Journal of Family & Reproductive Health
https://www.readbyqxmd.com/read/28538378/effects-of-intensive-training-on-menstrual-function-and-certain-serum-hormones-and-peptides-related-to-the-female-reproductive-system
#17
Geum Joon Cho, Sung Won Han, Jung-Ho Shin, Tak Kim
The aim of this study was to assess the effects of intensive training on menstrual function and related serum hormones and peptides.Forty female participants who attended a training course for an officer at the Korea Third Military Academy, and had regular menstrual periods were enrolled. Menstrual questionnaires and fasting blood samples were collected before entry and at 4-week intervals for 8 weeks. The levels of corticotropin-releasing hormone (CRH), cortisol, prolactin, endorphin-β, neuropeptide Y (NPY), leptin, orexin-A, ghrelin, follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), thyrotropin (TSH), and thyroxine (T4) were determined...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28535443/independent-validation-of-body-fluid-specific-cpg-markers-and-construction-of-a-robust-multiplex-assay
#18
Hannah Holtkötter, Vanessa Beyer, Kristina Schwender, Alina Glaub, Kristina Schulze Johann, Marianne Schürenkamp, Ursula Sibbing, Sabrina Banken, Peter Wiegand, Heidi Pfeiffer, Lynn Dennany, Marielle Vennemann, Marielle Vennemann
Potential forensic use of tissue-specific DNA methylation markers has recently been discussed for the identification of the biological source of a stain. In this study 13 promising markers were evaluated to identify suitable candidate markers for the development of a robust and reliable multiplex assay. The results of this study suggest that a combination of only four highly informative markers will be enough for clear body fluid identification. A multiplex assay was developed for the identification of menstrual blood, saliva, semen, and venous blood...
May 9, 2017: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/28523292/angiogenesis-versus-arteriogenesis
#19
Anna Rizzi, Vincenzo Benagiano, Domenico Ribatti
In the vascular system, angiogenesis and arteriogenesis play a unique yet equally important role in both health and disease. Angiogenesis, the formation of new blood vessels from a preexisting vascular bed, occurs naturally during wound healing, the female menstrual cycle and pregnancy. It plays a critical role in tissue growth and repair, and is a highly controlled process that is dependent on an intricate balance of both pro-angiogenic (to stimulate) and anti-angiogenic (to negatively regulate the phenomenon) factors...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28522756/influence-of-sex-menstrual-cycle-and-oral-contraceptives-on-cerebrovascular-resistance-and-cardiorespiratory-function-during-valsalva-or-standing
#20
Syed Abidi, Misha Nili, Stephania Serna, Simon Kim, Christopher Hazlett, Heather Edgell
Women experience orthostatic intolerance more than men, and experience faintness more in the early follicular (i.e. low hormone (LH)) compared to the luteal (i.e. high hormone (HH)) phase of the menstrual cycle. Men (n=13, age: 25.8±1.8) and women in the LH (day 2-5; placebo) and HH) (day 18-24; high dose) phases of the menstrual cycle with (OC; n=14, age: 22.0±0.8) or without oral contraceptives (NOC; n=12, age: 21.8±0.5) underwent the Valsalva maneuver and a supine-sit-stand protocol. Blood pressure, normalized stroke volume (SVi), cardiac output index (Qi), heart rate (HR), end-tidal carbon dioxide (ET-CO2), and middle cerebral artery blood velocity (MCA) were measured...
May 18, 2017: Journal of Applied Physiology
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