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https://www.readbyqxmd.com/read/28812221/multimodal-neuroimaging-in-schizophrenia-description-and-dissemination
#1
C J Aine, H J Bockholt, J R Bustillo, J M Cañive, A Caprihan, C Gasparovic, F M Hanlon, J M Houck, R E Jung, J Lauriello, J Liu, A R Mayer, N I Perrone-Bizzozero, S Posse, J M Stephen, J A Turner, V P Clark, Vince D Calhoun
In this paper we describe an open-access collection of multimodal neuroimaging data in schizophrenia for release to the community. Data were acquired from approximately 100 patients with schizophrenia and 100 age-matched controls during rest as well as several task activation paradigms targeting a hierarchy of cognitive constructs. Neuroimaging data include structural MRI, functional MRI, diffusion MRI, MR spectroscopic imaging, and magnetoencephalography. For three of the hypothesis-driven projects, task activation paradigms were acquired on subsets of ~200 volunteers which examined a range of sensory and cognitive processes (e...
August 15, 2017: Neuroinformatics
https://www.readbyqxmd.com/read/28810112/patient-and-physician-perceptions-of-genetic-testing-in-primary-care
#2
Samuel A Evenson, H Eugene Hoyme, Jan E Haugen-Rogers, Eric A Larson, Susan E Puumala
INTRODUCTION: The convergence of biomedical informatics and translational genomics is changing the way we practice. Primary care will play a pivotal role in this transformation. We therefore sought to assess general knowledge about genetic testing among outpatient internal medicine providers, and the patients that they serve across a five state region in the Midwest. METHODS: One thousand take-home paper surveys were created and distributed to internal medicine patients at 13 Midwestern clinics...
November 2016: South Dakota Medicine: the Journal of the South Dakota State Medical Association
https://www.readbyqxmd.com/read/28809202/creativity-as-a-key-driver-for-designing-context-sensitive-health-informatics
#3
Chunfang Zhou, Christian Nøhr
In order to face the increasing challenges of complexity and uncertainty in practice of health care, this paper aims to discuss how creativity can contribute to design new technologies in health informatics systems. It will firstly introduce the background highlighting creativity as a missing element in recent studies on context sensitive health informatics. Secondly, the concept of creativity and its relationship with activities of technology design will be discussed from a socio-culture perspective. This will be thirdly followed by understanding the roles of creativity in designing new health informatics technologies for meeting needs of high context sensitivity...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28809196/health-informatics-and-technology-for-integrated-elderly-care-in-the-context-of-hong-kong-a-case-study
#4
Cheuk Wing Chau, Eman Leung
The aging population creates tremendous pressure to healthcare. To resolve, scholars recognized the solution to this challenge is integrated care. To facilitate integrated care, health information technologies (HIT) is a critical enabler. This paper will first review how technology enhanced integrated care, and review on the existing literatures in system effective use and the three key external factors that enable HIT implementation. Applying Burton-Jones and Volkoff's contextualized theories of effective use of HIT to understand the role of health informatics and technology in the unique context of Hong Kong, we have conducted a case study research to identify the levers for improving HK integration of care through HIT...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28809195/pok%C3%A3-mon-go-why-augmented-reality-games-offer-insights-for-enhancing-public-health-interventions-on-obesity-related-diseases
#5
Ming Chao Wong, Paul Turner, Kate MacIntyre, Kwang Chien Yee
Stimulating widespread interests of the population to participate in behavioural changes through information and technology has been an aim of much health informatics research. The recent widespread participation of the augmented reality game Pokémon Go which encourages exercises, provides significant insights into the potential of information technology to improve healthcare intervention on obesity-related disease. Does Pokémon Go point to another way of achieving health benefits using mobile devices? This paper analyses the features of Pokémon Go in relation to potential health benefits...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28809185/a-quality-benefit-cost-and-financial-framework-for-health-information-technology-e-prescribing-a-delphi-study
#6
Paul R DeMuro, Joan Ash, Blackford Middleton, Justin Fletcher, Cecelia J Madison
BACKGROUND: Little research has been conducted about the quality, benefits, costs, and financial considerations associated with health information technology (HIT), particularly informatics technologies, such as e-prescribing, from the perspective of all its stakeholders. OBJECTIVES: This research effort sought to identify the stakeholders involved in e-prescribing and to identify and rank-order the positives and the negatives from the perspective of the stakeholders to create a framework to assist in the development of incentives and payment mechanisms which result in better managed care...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28809182/developing-an-assessment-tool-for-enhancing-interprofessional-education-of-patient-safety
#7
Yang Gong
The increasing recognition of the value of effective interprofessional collaboration has promoted interprofessional education (IPE) among healthcare professionals. The IPE pilot program initiative at UTHealth matriculated students from the disciplines of biomedical informatics, biomedical sciences, dentistry, medicine, nursing and public health. There has been a pressing need for developing an assessment tool in reflecting how IPE participants recognize and understand the other disciplines including clinical informatics in nowadays' practice...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28809176/potential-of-decision-support-in-preventing-pressure-ulcers-in-hospitals
#8
Ju Wang, Yang Gong
The development of hospital-acquired pressure ulcers signals low quality of care. Despite the established guidelines and best practices on pressure ulcer prevention, the incidence of pressure ulcers in hospital remains high. To meet the challenges of consistently translating best practices into effective clinical practices and promote effective teamwork communication and interprofessional collaboration, we consider the failure of consistent care delivery as loss of information and reveal the opportunities of informatics methods to reinforce information delivery, evidenced by typical cases...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28809175/the-use-of-data-analytics-to-build-an-australian-context-sensitive-health-informatics-framework-for-consumer-directed-community-aged-care
#9
Andrew Georgiou, Mikaela Jorgensen, Joyce Siette, Johanna I Westbrook
The challenge of providing services that meet the growing needs of an ageing population is one confronted by communities across Australia and internationally. The aim of this study was to: a) undertake semi-structured interviews and focus groups across a sample of service and technical staff to identify the interconnection between communication, information, work practices and performance; and b) carry out a comprehensive review of existing data sources to identify the data linkages required to identify and monitor performance across different dimensions of the quality of aged care spectrum...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28809174/theoretical-approaches-to-investigate-context-sensitive-health-informatics-that-will-generate-robust-evidence
#10
(no author information available yet)
No abstract text is available yet for this article.
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28809173/context-sensitive-health-informatics-delivering-21st-century-healthcare-building-a-quality-and-efficiency-driven-system
#11
Zoie Shui-Yee Wong, Christian Nøhr, Craig E Kuziemsky, Eman Leung, Frank Chen
Health informatics applications will be a cornerstone in the next generation quality-and-efficiency health care system. Health care is delivered from many different specialties, to many different patients with complex diseases and comorbidity. A one size fits all approach is not adequate to reach the Triple Aim of improving the patient experience of care, improving the health of populations, and reducing the per capita cost of health care. Health informatics applications must be built to be adaptable and sensitive to the complex contexts they will be used in...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28808132/defining-electron-bifurcation-in-the-electron-transferring-flavoprotein-family
#12
Amaya M Garcia Costas, Saroj Poudel, Anne-Frances Miller, Gerrit J Schut, Rhesa N Ledbetter, Kathryn R Fixen, Lance C Seefeldt, Michael W W Adams, Caroline S Harwood, Eric S Boyd, John W Peters
Electron bifurcation is the coupling of exergonic and endergonic redox reactions to simultaneously generate (or utilize) low and high potential electrons. It is the third recognized form of energy conservation in biology and has recently been described in select electron transferring flavoproteins (Etfs). Etfs are flavin-containing heterodimers best known for donating electrons derived from fatty acid and amino acid oxidation to an electron transfer respiratory chain via ETF quinone oxidoreductase. Canonical examples contain a flavin adenine dinucleotide (FAD) that is involved in electron transfer as well as a non-redox active adenosine monophosphate (AMP)...
August 14, 2017: Journal of Bacteriology
https://www.readbyqxmd.com/read/28807893/optimizing-the-use-of-electronic-health-records-to-identify-high-risk-psychosocial-determinants-of-health
#13
Nicolas Michel Oreskovic, Jennifer Maniates, Jeffrey Weilburg, Garry Choy
BACKGROUND: Care coordination programs have traditionally focused on medically complex patients, identifying patients that qualify by analyzing formatted clinical data and claims data. However, not all clinically relevant data reside in claims and formatted data. Recently, there has been increasing interest in including patients with complex psychosocial determinants of health in care coordination programs. Psychosocial risk factors, including social determinants of health, mental health disorders, and substance abuse disorders, are less amenable to rapid and systematic data analyses, as these data are often not collected or stored as formatted data, and due to US Health Insurance Portability and Accountability Act (HIPAA) regulations are often not available as claims data...
August 14, 2017: JMIR Medical Informatics
https://www.readbyqxmd.com/read/28806233/enhancing-key-competencies-of-health-professionals-in-the-assessment-and-care-of-adults-at-risk-of-suicide-through-education-and-technology
#14
Kathryn Ryan, Claudia Tindall, Gillian Strudwick
PURPOSE: This article describes efforts undertaken to improve the clinical competencies of health professionals in the area of suicide risk assessment, documentation, and care planning. DESCRIPTION OF THE PROJECT: Best practices that fit the mental health and addictions setting were identified from the Registered Nurses' Association of Ontario Best Practice Guideline on Assessment and Care of Adults at Risk for Suicidal Ideation and Behaviour. A variety of methods were used to implement the guidelines at the Centre for Addiction and Mental Health in Toronto, Ontario, Canada...
September 2017: Clinical Nurse Specialist CNS
https://www.readbyqxmd.com/read/28802333/solving-the-adoption-bottleneck-to-streamline-application-of-medical-informatics
#15
EDITORIAL
Ming-Chin Lin, Usman Iqbal, Yu-Chuan Jack Li
No abstract text is available yet for this article.
October 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28802167/induction-of-senescence-in-cancer-cells-by-5-aza-2-deoxycytidine-bioinformatics-and-experimental-insights-to-its-targets
#16
Jayarani F Putri, Nashi Widodo, Kazuichi Sakamoto, Sunil C Kaul, Renu Wadhwa
5'-Aza-2'-deoxycytidine (5-Aza-dC) is a demethylating drug that causes genome-wide hypomethylation resulting in the expression of several tumor suppressor genes causing growth arrest of cancer cells. Cancer is well established as a multifactorial disease and requires multi-module therapeutics. Search for new drugs and their approval by FDA takes a long time. Keeping this in view, research on new functions of FDA-approved anticancer drugs is desired to expand the list of multi-module functioning drugs for cancer therapy...
August 2, 2017: Computational Biology and Chemistry
https://www.readbyqxmd.com/read/28801508/intricate-and-cell-type-specific-populations-of-endogenous-circular-dna-eccdna-in-caenorhabditis-elegans-and-homo-sapiens
#17
Massa J Shoura, Idan Gabdank, Loren Hansen, Jason Merker, Jason Gotlib, Stephen D Levene, Andrew Z Fire
Investigations aimed at defining the 3-D configuration of eukaryotic chromosomes have consistently encountered an endogenous population of chromosome-derived circular genomic DNA, referred to as extrachromosomal circular DNA (eccDNA). While the production, distribution, and activities of eccDNAs remain understudied, eccDNA formation from specific regions of the linear genome has profound consequences on the regulatory and coding capabilities for these regions. Here, we define eccDNA distributions in C. elegans and in three human cell types, utilizing a set of DNA-topology dependent approaches for enrichment and characterization...
August 11, 2017: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/28800061/applying-sensor-based-technology-to-improve-construction-safety-management
#18
REVIEW
Mingyuan Zhang, Tianzhuo Cao, Xuefeng Zhao
Construction sites are dynamic and complicated systems. The movement and interaction of people, goods and energy make construction safety management extremely difficult. Due to the ever-increasing amount of information, traditional construction safety management has operated under difficult circumstances. As an effective way to collect, identify and process information, sensor-based technology is deemed to provide new generation of methods for advancing construction safety management. It makes the real-time construction safety management with high efficiency and accuracy a reality and provides a solid foundation for facilitating its modernization, and informatization...
August 11, 2017: Sensors
https://www.readbyqxmd.com/read/28797947/the-challenges-of-using-high-throughput-sequencing-to-track-multiple-bipartite-mycoviruses-of-wild-orchid-fungus-partnerships-over-consecutive-years
#19
Jamie W L Ong, Hua Li, Krishnapillai Sivasithamparam, Kingsley W Dixon, Michael G K Jones, Stephen J Wylie
The bipartite alpha- and betapartitiviruses are recorded from a wide range of fungi and plants. Using a combination of dsRNA-enrichment, high-throughput shotgun sequencing and informatics, we report the occurrence of multiple new partitiviruses associated with mycorrhizal Ceratobasidium fungi, themselves symbiotically associated with a small wild population of Pterostylis sanguinea orchids in Australia, over two consecutive years. Twenty-one partial or near-complete sequences representing 16 definitive alpha- and betapartitivirus species, and further possible species, were detected from two fungal isolates...
August 7, 2017: Virology
https://www.readbyqxmd.com/read/28797293/health-care-providers-perceptions-of-use-and-influence-of-clinical-decision-support-reminders-qualitative-study-following-a-randomized-trial-to-improve-hpv-vaccination-rates
#20
Brian E Dixon, Monica L Kasting, Shannon Wilson, Amit Kulkarni, Gregory D Zimet, Stephen M Downs
BACKGROUND: Human Papillomavirus (HPV) leads to serious health issues and remains the most common sexually transmitted infection. Despite availability of effective vaccines, HPV vaccination rates are suboptimal. Furthermore, providers recommend the HPV vaccine less than half the time for eligible patients. Prior informatics research has demonstrated the effectiveness of computer-based clinical decision support (CDS) in changing provider behavior, especially in the area of preventative services...
August 10, 2017: BMC Medical Informatics and Decision Making
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