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Fgd pet

Sivanath Reddy Gajjala, Narendra Hulikal, Silpa Kadiyala, Radhika Kottu, Tekchand Kalawat
Background & objectives: Locally advanced breast cancer (LABC) is associated with substantial risk of occult metastases. The patients with LABC have high rate of systemic relapse, suggesting inadequacy of the current conventional staging in detecting the occult metastatic spread. 18 F-fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET/CT) is a new modality in the staging of breast cancer patients. Hence, this study was conducted to evaluate the role of 18 F-FDG PET/CT in initial staging of LABC and to compare it with conventional methods...
March 2018: Indian Journal of Medical Research
Alessandra Invento, Sara Mirandola, Francesca Pellini, Giovanni Paolo Pellino, Daniela Grigolato
INTRODUCTION: Invasive lobular cancer (ILC) is the second most common type of a heterogeneous group of different histological types of invasive breast carcinoma. Breast cancer can metastatize anywhere, the most common sites are bones, liver, lungs and brain. Gastrointestinal tract (GI) metastases observed in autopsy studies account for about 6% to 18% of the overall metastases from breast cancer. OBJECTIVE: We describe a 54-year old woman with recurrent ILC in the contralateral breast...
2018: Annali Italiani di Chirurgia
Evan C Frary, Søren Hess, Oke Gerke, Helle Laustrup
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a group of autoimmune diseases characterized by systemic inflammation in small- to medium-sized blood vessels. Although immunosuppressive therapy has greatly improved the prognosis for these patients, there are still significant comorbidities, such as cancer and infection, associated with AAV. These comorbidities are often indistinguishable from an underlying AAV disease relapse, and create a clinical conundrum, as these conditions are normally contraindications for immunosuppressive treatment...
July 2017: Medicine (Baltimore)
Jae-Cheol Jo, Dok Hyun Yoon, Shin Kim, Kyoungmin Lee, Eun Hee Kang, Jung Sun Park, Jin-Sook Ryu, Jooryung Huh, Chan-Sik Park, Jong Hoon Kim, Sang Wook Lee, Cheolwon Suh
18F-fluoro-2-dexoy-D-glucose-positron emission tomography (PET)/computed tomography (CT) is a useful imaging technique for monitoring the treatment response in lymphoma cases. We investigated the value of interim brain PET/CT (I-PET/CT) for monitoring the response to intensive methotrexate-based chemotherapy in primary central nervous system lymphoma (PCNSL) patients with diffuse large B cell lymphoma (DLBCL). Of the 76 PCNSL patients treated with intensive methotrexate and cytarabine chemotherapy between September 2006 and December 2012, 66 patients with DLBCL were included in this study...
September 2017: Annals of Hematology
Darshan C Patel, Senthil S Gunasekaran, Christopher Goettl, Nadera J Sweiss, Yang Lu
PURPOSE: This retrospective study investigates the relationship between cardiac and extra-thoracic sarcoid findings on FDG PET-CT using a 72-hour pretest high-fat, high-protein, and very low-carbohydrate (HFHPVLC) diet. PATIENTS AND METHODS: A total of 196 consecutive FDG PET-CT scans with 72-hour HFHPVLC diet preparation were performed between December 2014 and December 2015 in known sarcoid patients. Of these scans, 5 were excluded for non-adherence to diet preparation or underlying cancer...
July 5, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
Steven J Verberne, Remko J A Sonnega, Olivier P P Temmerman, Pieter G Raijmakers
BACKGROUND: In the assessment of possible periprosthetic knee infection, various imaging modalities are used without consensus regarding the most accurate technique. QUESTIONS/PURPOSES: To perform a meta-analysis to compare the accuracy of various applied imaging modalities in the assessment of periprosthetic knee infection. METHODS: A systematic review and meta-analysis was conducted with a comprehensive search of MEDLINE and Embase® in accordance with the PRISMA and Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) recommendations to identify clinical studies in which periprosthetic knee infection was investigated with different imaging modalities...
May 2017: Clinical Orthopaedics and related Research
Hugo J A Adams, Thomas C Kwee
PURPOSE: To systematically review and meta-analyze the proportion of false-positive lesions at interim and end-of-treatment (18)F-fluoro-2-deoxy-d-glucose positron emission tomography (FDG-PET) in lymphoma using biopsy as reference standard. MATERIALS AND METHODS: Medline was searched for original studies. Methodological quality of included studies was evaluated, and results were meta-analytically summarized using random effects (in case of interstudy heterogeneity [I(2)≤50%]) or fixed effects (in case of no interstudy heterogeneity [I(2)>50%])...
November 2016: European Journal of Radiology
Valerie A Paz-Soldan, Josh Yukich, Amara Soonthorndhada, Maziel Giron, Charles S Apperson, Loganathan Ponnusamy, Coby Schal, Amy C Morrison, Joseph Keating, Dawn M Wesson
BACKGROUND: Dengue virus (and Chikungunya and Zika viruses) is transmitted by Aedes aegypti and Aedes albopictus mosquitoes and causes considerable human morbidity and mortality. As there is currently no vaccine or chemoprophylaxis to protect people from dengue virus infection, vector control is the only viable option for disease prevention. The purpose of this paper is to illustrate the design and placement process for an attractive lethal ovitrap to reduce vector populations and to describe lessons learned in the development of the trap...
2016: PloS One
Beata Ewa Chrapko, Marek Chrapko, Anna Nocuń, Bogusław Stefaniak, Tomasz Zubilewicz, Andrzej Drop
This review article discusses the utility of 18F-FDG PET/CT in diagnosis and management of vascular disease. We stress usefulness of this method in large vessel inflammation and infection. In our work we based on the literature analysis and clinical cases diagnosed in our institution by use of 18F-FDG PET/CT. The literature exploration was focusing on vascular inflammation and infections and 18-FDG PET. The search was performed on PubMed database and cross referencing. We present the practical review with several images of vascular diseases like: Takayasu arteritis, giant cell arteritis, vascular graft infections, abdominal aortic aneurysm infections and cases of aortitis and periaortitis...
2016: Nuclear Medicine Review. Central & Eastern Europe
Sung Gwe Ahn, Minkyung Lee, Tae Joo Jeon, Kyunghwa Han, Hak Min Lee, Seung Ah Lee, Young Hoon Ryu, Eun Ju Son, Joon Jeong
BACKGROUND: Patients with hormone receptor-positive breast cancer typically show favorable survival. However, identifying individuals at high risk of recurrence among these patients is a crucial issue. We tested the hypothesis that [18F]-fluorodeoxyglucose positron emission tomography (FDG-PET) scans can help predict prognosis in patients with hormone receptor-positive breast cancer. METHODS: Between April 2004 and December 2008, 305 patients with hormone receptor-positive breast cancer who underwent FGD-PET were enrolled...
2014: PloS One
Mikkel Malham, Søren Hess, Rasmus G Nielsen, Steffen Husby, Poul Flemming Høilund-Carlsen
The literature on positron emission tomography and computed tomography using (18)fluoro-deoxyglusose (FDG-PET/CT) in the diagnosis of pediatric inflammatory bowel disease (IBD) is presented. Only five papers representing independent studies were identified and included in this review. Of these, two studies dealt with both stand-alone FDG-PET and FDG-PET/CT, while three were about stand-alone FDG-PET only. No studies could be found that focused on FDG-PET/CT only. The five studies comprised analysis of a total 181 pediatric patients (0-18 years of age)...
2014: American Journal of Nuclear Medicine and Molecular Imaging
Guillemette Fouquet, Stéphanie Guidez, Charles Herbaux, Zoé Van de Wyngaert, Sarah Bonnet, David Beauvais, Hélène Demarquette, Salim Adib, Bénédicte Hivert, Mathieu Wemeau, Céline Berthon, Louis Terriou, Valérie Coiteux, Margaret Macro, Olivier Decaux, Thierry Facon, Damien Huglo, Xavier Leleu
PURPOSE: Solitary plasmacytoma (SP) is a localized proliferation of monoclonal plasma cells in either bone or soft tissue, without evidence of multiple myeloma (MM), and whose prognosis is marked by a high risk of transformation to MM. EXPERIMENTAL DESIGN: We studied the impact of FDG-PET/CT (2[18F]fluoro-2-deoxy-D-glucose positron emission tomography-computed tomography) on the risk of transformation of SP to overt MM among other markers in a series of 43 patients diagnosed with SP...
June 15, 2014: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
Adriano Massimiliano Priola, Sandro Massimo Priola
Rebound thymic hyperplasia (RTH) with increased (18)F-FGD uptake at positron emission tomography (PET) computed tomography (CT) is typical of pediatric patients after chemotherapy, although it may occasionally occur in adults. At CT, RTH usually appears as a diffusely enlarged thymus with areas of fatty attenuation. We report two cases of RTH in adults detected at follow-up: both showed unusual morphology on CT and were confirmed at PET-CT as areas of strongly increased radiopharmaceutical uptake, which suggested disease recurrence...
September 2014: Clinical Imaging
Ciğdem Soydal, Cabir Yüksel, Nuriye Özlem Küçük, Ilker Okten, Elgin Ozkan, Beyza Doğanay Erdoğan
OBJECTIVE: In this study, we aimed to explore prognostic importance of definition of preoperative metabolic tumor volume in esophageal cancer patients. METHODS: 22 patients who have histologically proven stage IIA-III esophageal cancer and underwent (18)F-FDG PET/CT for preoperative staging of disease were included to the study. After (18)F-FDG PET/CT, all the patients underwent surgery within 4 weeks period. Patients have been followed up until death or Sept 15(th), 2012...
February 2014: Molecular Imaging and Radionuclide Therapy
Ning Xing, Zu-Long Cai, Shao-Hong Zhao, Li Yang, Bai-Xuan Xu, Fu-Lin Wang
OBJECTIVE: To investigate the validity of CT perfusion in assessing angiogenic activity of lung cancer. METHODS: Fifty-six patients with lung cancer scheduled for elective surgical resection received 16-slice helical CT perfusion imaging. Time-density curve (TDC), blood flow (BF), blood volume (BV), mean transmit time (MTT) and permeability surface area product (PS) were calculated. 18F-deoxyglucose-positron emission tomography (FGD-PET) was carried out in 14 out of the 56 patients to calculate standardized uptake values (SUVs)...
June 2011: Chinese Journal of Cancer Research, Chung-kuo Yen Cheng Yen Chiu
Monika Klirova, Jiri Horacek, Tomas Novak, Jan Cermak, Filip Spaniel, Lucie Skrdlantova, Pavel Mohr, Cyril Höschl
Low-frequency repetitive transcranial magnetic stimulation (LF-rTMS) of the left temporo-parietal cortex (LTPC) has been proposed as a useful therapeutic method for auditory hallucinations (AHs). Stereotactic neuronavigation enables the magnetic coil to be targeted according to the individual parameters obtained from neuroimaging. Individualized rTMS neuronavigated according to 18-fluorodeoxyglucose positron emission tomography ((18)FDG PET) allows us to focus the coil explicitly on a given area with detected maxima of specific abnormalities, thus presuming a higher therapeutic effect of the method...
September 2013: European Archives of Psychiatry and Clinical Neuroscience
Natalia Goldberg, Yulia Kundel, Ofer Purim, Hanna Bernstine, Noa Gordon, Sara Morgenstern, Efraim Idelevich, Nir Wasserberg, Aaron Sulkes, David Groshar, Baruch Brenner
BACKGROUND: Preoperative radiochemotherapy (RCT) is standard in locally advanced rectal cancer (LARC). Initial data suggest that the tumor's metabolic response, i.e. reduction of its 18 F-FDG uptake compared with the baseline, observed after two weeks of RCT, may correlate with histopathological response. This prospective study evaluated the ability of a very early metabolic response, seen after only one week of RCT, to predict the histopathological response to treatment. METHODS: Twenty patients with LARC who received standard RCT regimen followed by radical surgery participated in this study...
August 1, 2012: Radiation Oncology
Tsutomu Soma, Toshimitsu Momose, Miwako Takahashi, Keitraro Koyama, Kensuke Kawai, Kenya Murase, Kuni Ohtomo
OBJECTIVE: Inter-ictal (18)F-2-fluoro-deoxy-D: -glucose-positron emission tomography (FDG-PET) is widely used for preoperative evaluation to identify epileptogenic zones in patients with temporal lobe epilepsy. In this study, we combined statistical parametric mapping (SPM) with the asymmetry index and volume-of-interest (VOI) based extent analysis employing preoperative FDG-PET in unilateral mesial temporal lobe epilepsy (MTLE) patients. We also evaluated the detection utility of these techniques for automated identification of abnormalities in the unilateral hippocampal area later confirmed to be epileptogenic zones by surgical treatment and subsequent good seizure control...
May 2012: Annals of Nuclear Medicine
J Leseur, A Devillers, D Williaume, E Le Prisé, C Fougerou, C Bouriel, J Levêque, E Monpetit, J Blanchot, R de Crevoisier, E Garin
PURPOSE: In cervix carcinoma: (a) to evaluate the ability of ((18)F)-fluorodeoxyglucose (FDG) positron emission tomography (PET) in the lymph node detection; (b) to investigate the prognostic and predictive value of the primary cervical PET parameters. PATIENTS AND METHODS: Ninety patients treated for cervix carcinoma and evaluated initially by MRI and FGD PET were included. The performances of FDG-PET for lymph node detection (relatively to the lymph node dissection) have been described (sensitivity, specificity, positive predictive value and negative predictive value)...
December 2011: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
L Magnani, A Versari, D Salvo, M Casali, G Germanò, R Meliconi, L Pulsatelli, D Formisano, G Bajocchi, N Pipitone, L Boiardi, C Salvarani
Disease activity assessment in large vessel vasculitis (LVV) is often challenging for physicians. In this study, we compared the assessment of disease activity based on inflammatory markers, clinical indices (Indian Takayasu Activity Score [ITAS] and the Kerr/National Institute of Health indices [Kerr/NIH]), and 18F-Fluorodesossiglucose (FGD) vascular uptake at positron emission tomography (Pet). We found that Pet results did not statistically correlate with the clinical indices ITAS and Kerr/NIH, because FDG uptake was increased (grade>2 on a 0-3 scale in at least one evaluated vascular segment) in many patients with inactive disease according to clinical and laboratory parameters (i...
2011: Reumatismo
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