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Skin internal medicine

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https://www.readbyqxmd.com/read/28101614/-dermatological-topical-and-systemic-therapy-during-pregnancy
#1
REVIEW
S Grunewald, P Staubach
During pregnancy, a successful and safe therapeutic management of patients is possible to lower the burden of disease. Often topical therapy in combination with intensive basic skin care is sufficient. Drug therapies may also be used, most often for systemic diseases such as autoimmune diseases or psoriasis. An early change in therapy is also key during planned pregnancies so that treatments can be switched, adjusted, reduced or closely monitored. Another point to consider is to keep drug dosing as low as possible (without occlusion in local therapy) or short termed (with the exception of autoimmune or malignant diseases)...
January 18, 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/28100272/bibliometric-analysis-of-literature-on-toxic-epidermal-necrolysis-and-stevens-johnson-syndrome-1940-2015
#2
Waleed M Sweileh
BACKGROUND: Stevens Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but fatal adverse skin reactions that affect all age groups. In order to better understand literature on this topic, we conducted a bibliometric study using Scopus database to shed light on number and growth of publications, most active countries, institutions, journals and authors involved in publishing articles in this field, citation analysis, top cited articles, international collaboration, role of medications and genetic association...
January 18, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/28089672/isopropyl-alcohol-is-as-efficient-as-chlorhexidine-to-prevent-contamination-of-blood-cultures
#3
Jovanna Martínez, Juan H Macías, Virginia Arreguín, Jose A Álvarez, Alejandro E Macías, Juan L Mosqueda-Gómez
BACKGROUND: False-positive blood cultures can lead to unnecessary risks and misuse of antibiotics; to reduce rates of false-positives, it would be useful to determine whether use of an antiseptic with a prolonged effect is required. METHODS: Clinical study of efficacy (blinded and randomized) to compare the rate of blood culture contamination when skin antisepsis was performed with 70% isopropyl alcohol or 2% chlorhexidine gluconate in 70% isopropyl alcohol in 2 hospitals...
January 12, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28088378/antimicrobial-coated-implants-in-trauma-and-orthopaedics-a-clinical-review-and-risk-benefit-analysis
#4
REVIEW
Volker Alt
Implant-associated infections remain a major issue in orthopaedics and antimicrobial functionalization of the implant surface by antibiotics or other anti-infective agents have gained interest. The goal of this article is to identify antimicrobial coatings, for which clinical data are available and to review their clinical need, safety profile, and their efficacy to reduce infection rates. PubMed database of the National Library of Medicine was searched for clinical studies on antimicrobial coated implants for internal fracture fixation devices and endoprostheses for bone surgery, for which study design, level of evidence, biocompatibility, development of resistance, and effectiveness to reduce infection rates were analyzed...
December 21, 2016: Injury
https://www.readbyqxmd.com/read/28035448/lipoinjection-and-multiple-internal-cuts-for-congenital-constriction-bands-a-new-treatment-approach
#5
Yanko Castro-Govea, Amin Vela-Martinez, Luis Alberto Treviño-Garcia
BACKGROUND: Traditional treatment for a congenital constriction band of the limb involves multiple Z-plasties and W-plasties. We propose an alternative surgical procedure for the treatment of congenital constriction bands that obviates the need for Z-plasties and eliminates the constriction band. METHODS: We present the case of a 36-year-old woman with a congenital constriction band of the leg. Using a minimally invasive approach, the skin segment that included the band was dissected from the deep tissues...
December 29, 2016: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28032161/psychological-and-psychiatric-traits-in-post-bariatric-patients-asking-for-body-contouring-surgery
#6
Chiara Pavan, Massimo Marini, Eleonora De Antoni, Carlotta Scarpa, Tito Brambullo, Franco Bassetto, Annapina Mazzotta, Vincenzo Vindigni
BACKGROUNDS: Obese patients, mainly females, feel uncomfortable and unsatisfied with their physical appearance; they have a wrong perception of their image and consequently diminish their self-esteem, sometimes showing difficulties in functional areas such as work, relationship, social activity. Beside health concerns, improving their appearance and body image are often common motives for weight loss in obese individuals and after weight loss about 30% of bariatric surgery patients undergo plastic surgical correction of excessive skin...
December 28, 2016: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28031958/life-as-an-early-career-researcher-interview-with-kavita-beri
#7
Kavita Beri
Kavita Beri speaks to Francesca Lake, Managing Editor. Kavita Beri is a board certified Internal Medicine physician in the United States, and is an active member of the American Society of Laser Medicine and Surgery. She is the medical director and owner of BE Skin & Laser Med Spa, an aesthetic medicine practice in NJ, USA. She holds a position as a Visiting Scientist at the Department of Biomaterials and Center for Dermal Research at Rutgers University (NJ, USA) and is an active staff member in the Department of Medicine at Jersey Shore University Medical Center (NJ, USA)...
June 2016: Future Science OA
https://www.readbyqxmd.com/read/28028453/identification-and-characterization-of-daldinia-eschscholtzii-isolated-from-skin-scrapings-nails-and-blood
#8
Kee Peng Ng, Chai Ling Chan, Su Mei Yew, Siok Koon Yeo, Yue Fen Toh, Hong Keat Looi, Shiang Ling Na, Kok Wei Lee, Wai-Yan Yee, Chee Sian Kuan
BACKGROUND: Daldinia eschscholtzii is a filamentous wood-inhabiting endophyte commonly found in woody plants. Here, we report the identification and characterization of nine D. eschscholtzii isolates from skin scrapings, nail clippings, and blood. METHODS: The nine isolates were identified based on colony morphology, light microscopy, and internal transcribed spacer (ITS)-based phylogeny. In vitro antifungal susceptibility of the fungal isolates was evaluated by the Etest to determine the minimum inhibitory concentration (MIC)...
2016: PeerJ
https://www.readbyqxmd.com/read/28004308/cutaneous-side-effects-and-transepidermal-water-loss-to-gefitinib-a-study-of-11-patients
#9
Franky Chandra, Dendi Sandiono, Unwati Sugiri, Oki Suwarsa, Hendra Gunawan
INTRODUCTION: Cutaneous side effects caused by epidermal growth factor receptor (EGFR) inhibitors occurred in 45-100% of patients which may lead to therapy modification or interruption. This study aimed to evaluate cutaneous side effects and transepidermal water loss (TEWL) values in non-small cell lung carcinoma (NSCLC) patients who received gefitinib EGFR inhibitor. METHODS: A descriptive observational study with cross-sectional design and a consecutive sampling method was conducted from 1 February to 4 March 2016...
December 21, 2016: Dermatology and Therapy
https://www.readbyqxmd.com/read/27993822/calcitriol-mediated-hypercalcaemia-with-silicone-granulomas-due-to-cosmetic-injection
#10
Stephen Melnick, Ana Abaroa-Salvatierra, Mrunalini Deshmukh, Arti Patel
We present a case of a 41-year-old woman with medical history significant for urolithiasis presenting to our hospital for psychiatric evaluation due to worsening depression and suicidal ideations for the past 2 weeks. Initial laboratory results show hypercalcaemia of 13.5 mg/mL that led to consulting internal medicine. On further questioning, the patient admitted to cosmetic silicone injections in her buttocks which were causing calcium deposition under her skin, leading to disfigurement of the sacrum and lumbar regions...
December 19, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27968891/crowdsourcing-health-communication-about-condom-use-in-men-who-have-sex-with-men-in-china-a-randomised-controlled-trial
#11
Weiming Tang, Jessica Mao, Chuncheng Liu, Katie Mollan, Haochu Li, Terrence Wong, Ye Zhang, Songyuan Tang, Michael Hudgens, Yilu Qin, Baoli Ma, Meizhen Liao, Bin Yang, Wei Ma, Dianmin Kang, Chongyi Wei, Joseph D Tucker
BACKGROUND: The Chinese government now encourages innovation, and more specifically, crowdsourcing. Crowdsourcing, the process of shifting individual tasks to a large group, might reimagine health communication, making it more people-centred. We aimed to compare the effectiveness of a crowdsourced versus social marketing condom promotion video to promote condom use. METHODS: A non-inferiority randomised controlled trial was conducted in November 2015 in China. Men who have sex with men (MSM) aged 16 years or older who reported having had sexual contact without use of a condom in the preceding 3 months were recruited through a nationwide MSM website...
October 2016: Lancet
https://www.readbyqxmd.com/read/27892847/international-adoption-from-ethiopia-an-overview-of-the-health-status-at-arrival-in-belgium
#12
Lydia Van Kesteren, Marek Wojciechowski
BACKGROUND: Ethiopia is a densely populated country with a fast growing economy. Still socioeconomic and health issues render many children parentless. One thousand and twenty eight Ethiopian children have been adopted in Belgium from September 2005 to September 2015. Little has been published about their health status at arrival. METHODS: Three hundred and fifteen children adopted from Ethiopia were clinically evaluated at the Institute of Tropical Medicine in Antwerp from 1 January 2008 until 31 December 2014...
November 28, 2016: Acta Clinica Belgica
https://www.readbyqxmd.com/read/27878794/varicosities-of-the-lower-extremity-new-approaches-cosmetic-or-therapeutic-needs
#13
Luca Spinedi, Heiko Uthoff, Sasan Partovi, Daniel Staub
Varicose veins of the lower extremity (VVLE) are a frequently encountered vascular disorder in the general population. The general view that VVLE are a non-serious disease with primarily aesthetic impact is a common misconception, as the disease can have a significant negative impact on generic and disease-specific quality of life. Further, VVLE may be associated with potentially threatening clinical conditions, such as chronic venous ulceration, venous thromboembolism and haemorrhage from ruptured varicose veins...
2016: Swiss Medical Weekly
https://www.readbyqxmd.com/read/27809749/fish-hydrolysates-a-regulatory-perspective-of-bioactive-peptides
#14
Bert Gevaert, Lieselotte Veryser, Frederick Verbeke, Evelien Wynendaele, Bart De Spiegeleer
For the first time introduced on the Japanese market, bioactive fish hydrolysates are now available all over the world as food supplements, functional food ingredients or nutricosmeceuticals. They are generally produced from low value fish waste, an almost inexhaustible source of raw material, and are sold as high value products, making them economically interesting from a manufacturer's view point. Most of these products have health or structure/function claims on their packages with different actions like antihypertensive, blood-glucose lowering, anxiolytic, and skin anti-aging activities...
2016: Protein and Peptide Letters
https://www.readbyqxmd.com/read/27806156/reliability-and-photographic-equivalency-of-the-scar-cosmesis-assessment-and-rating-scar-scale-an-outcome-measure-for-postoperative-scars
#15
Jonathan Kantor
Importance: Until recently, no ideal valid, feasible, and reliable scar scale existed to effectively assess the quality of postoperative linear scars. The Scar Cosmesis Assessment and Rating (SCAR) scale was developed and validated as a tool to assess the quality of postoperative scars in clinical and research settings. Objective: To assess the reliability of using photographs in lieu of live patient scar rating assessments, and to determine the interrater and intrarater reliability of the SCAR scale...
January 1, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/27801787/effects-of-ganodermanondiol-a-new-melanogenesis-inhibitor-from-the-medicinal-mushroom-ganoderma-lucidum
#16
Ji-Woong Kim, Hong-Il Kim, Jong-Hyeon Kim, O-Chul Kwon, Eun-Suk Son, Chang-Soo Lee, Young-Jin Park
Ganoderma lucidum, a species of the Basidiomycetes class, has been attracting international attention owing to its wide variety of biological activities and great potential as an ingredient in skin care cosmetics including "skin-whitening" products. However, there is little information available on its inhibitory effect against tyrosinase activity. Therefore, the objectives of this study were to investigate the chemical composition of G. lucidum and its inhibitory effects on melanogenesis. We isolated the active compound from G...
October 27, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27773801/a-review-of-ethnoboatany-therapeutic-value-phytochemistry-and-pharmacology-of-crinum-macowanii-baker-a-highly-traded-bulbous-plant-in-southern-africa
#17
REVIEW
Alfred Maroyi
ETHNOPHARMACOLOGICAL RELEVANCE: Crinum macowanii is a deciduous bulbous plant which grows in east, central and southern Africa. Crinum macowanii has been used as herbal medicine by the indigenous people of east and southern Africa has for several centuries. The bulb, leaves and roots of C. macowanii are reported to possess diverse medicinal properties and used to treat or manage various human and animal diseases and ailments throughout its distributional range. Crinum macowanii is used traditionally as a remedy for boils, diarrhoea, fever, inflammation, respiratory system problems, skin rashes, tuberculosis, wounds and urinary tract problems...
December 24, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27737816/safety-evaluation-of-styrax-liquidus-from-the-viewpoint-of-genotoxicity-and-mutagenicity
#18
Mohammad Charehsaz, Rengin Reis, Sinem Helvacioglu, Hande Sipahi, Etil Guzelmeric, Ebru Turkoz Acar, Gamze Cicek, Erdem Yesilada, Ahmet Aydin
ETHNOPHARMACOLOGICAL RELEVANCE: Styrax liquidus is a resinous exudate (balsam) obtained from the wounded trunk of the Liquidambar orientalis Mill. (Hamamelidaceae). Styrax has been used for treatment of various ailments in Turkish folk medicine such as skin problems, peptic ulcers, nocturnal enuresis, parasitic infections, antiseptic or as expectorant. AIM OF STUDY: In spite of frequent use of styrax in Turkish folk medicine as well as once as a stabilizer in perfumery industry, negative reports have been noticed by the international authority for restriction its use based on some limited evidences from an in vitro study...
December 24, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27720464/the-skin-aging-exposome
#19
Jean Krutmann, Anne Bouloc, Gabrielle Sore, Bruno A Bernard, Thierry Passeron
The term "exposome" describes the totality of exposures to which an individual is subjected from conception to death. It includes both external and internal factors as well as the human body's response to these factors. Current exposome research aims to understand the effects all factors have on specific organs, yet today, the exposome of human skin has not received major attention and a corresponding definition is lacking. This review was compiled with the collaboration of European scientists, specialized in either environmental medicine or skin biology...
September 28, 2016: Journal of Dermatological Science
https://www.readbyqxmd.com/read/27717107/management-of-patients-with-ocular-manifestations-in-vesiculobullous-disorders-affecting-the-mouth
#20
REVIEW
M S Hansen, O N Klefter, H O Julian, A M Lynge Pedersen, S Heegaard
Pemphigoid and pemphigus diseases as well as Stevens-Johnson syndrome present as vesiculobullous disorders of the skin and may additionally involve both the oral cavity and the ocular surface. Ocular involvement ranges from mild irritation and dry eye disease to chronic conjunctivitis, symblepharon, eyelid malposition, ocular surface scarring and severe visual loss. In addition to diagnostic assessments, ophthalmologists must treat the dry eye and meibomian gland dysfunction components of these diseases using a stepladder approach, including eyelid hygiene and lubricants...
October 7, 2016: Oral Diseases
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