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https://www.readbyqxmd.com/read/28320196/extended-timed-up-and-go-assessment-as-a-clinical-indicator-of-cognitive-state-in-parkinson-s-disease
#1
Tess Evans, Alexa Jefferson, Michelle Byrnes, Sue Walters, Soumya Ghosh, Frank L Mastaglia, Brian Power, Ryan S Anderton
OBJECTIVE: To evaluate a modified extended Timed Up and Go (extended-TUG) assessment against a panel of validated clinical assessments, as an indicator of Parkinson's disease (PD) severity and cognitive impairment. METHODS: Eighty-seven participants with idiopathic PD were sequentially recruited from a Movement Disorders Clinic. An extended-TUG assessment was employed which required participants to stand from a seated position, walk in a straight line for 7m, turn 180° and then return to the start, in a seated position...
April 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28320130/spg2-mimicking-multiple-sclerosis-in-a-family-identified-using-next-generation-sequencing
#2
Anna Rubegni, Carla Battisti, Alessandra Tessa, Alfonso Cerase, Stefano Doccini, Alessandro Malandrini, Filippo M Santorelli, Antonio Federico
Several single gene disorders can potentially be overlooked in the differential diagnostic evaluation of patients with multiple sclerosis (MS). Pelizaeus-Merzbacher disease and spastic paraplegia type 2 are allelic X-linked disorders associated with defective myelination of the central nervous system and mutations in PLP1. Neurological symptoms are occasionally observed in female carriers of these mutations. Two women - the proposita (Pt1) and her mother (Pt2) - reported walking difficulties since adolescence and showed progressive cognitive decline...
April 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28320074/diagnostic-performance-of-clinical-examination-measures-and-pain-presentation-to-identify-patellofemoral-joint-osteoarthritis
#3
J J Stefanik, R Duncan, D T Felson, G Peat
OBJECTIVE: Test the diagnostic performance of a comprehensive set of tests and measures to discriminate patellofemoral (PF) from tibiofemoral (TF) osteoarthritis (OA). METHODS: The Clinical Assessment of the Knee Study is a study of knee pain in the general population. The presence of PF crepitus and pain with PF compression were assessed. Anterior knee pain (AKP) was determined from a knee pain map. Pain with stairs and walking on level ground were assessed with the WOMAC...
March 20, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28319983/reliability-and-validity-of-ten-consumer-activity-trackers-depend-on-walking-speed
#4
Tryntsje Fokkema, Thea J M Kooiman, Wim P Krijnen, Cees P VAN DER Schans, Martijn DE Groot
PURPOSE: To examine the test-retest reliability and validity of ten activity trackers for step counting at three different walking speeds. METHODS: Thirty-one healthy participants walked twice on a treadmill for 30 min while wearing 10 activity trackers (Polar Loop, Garmin Vivosmart, Fitbit Charge HR, Apple Watch Sport, Pebble Smartwatch, Samsung Gear S, Misfit Flash, Jawbone Up Move, Flyfit, and Moves). Participants walked three walking speeds for 10 min each; slow (3...
April 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28319165/psychosocial-and-environmental-correlates-of-active-and-passive-transport-behaviors-in-college-educated-and-non-college-educated-working-young-adults
#5
Dorien Simons, Ilse De Bourdeaudhuij, Peter Clarys, Katrien De Cocker, Bas de Geus, Corneel Vandelanotte, Jelle Van Cauwenberg, Benedicte Deforche
BACKGROUND: This study aimed to examine potential differences in walking, cycling, public transport and passive transport (car/moped/motorcycle) to work and to other destinations between college and non-college educated working young adults. Secondly, we aimed to investigate which psychosocial and environmental factors are associated with the four transport modes and whether these associations differ between college and non-college educated working young adults. METHODS: In this cross-sectional study, 224 working young adults completed an online questionnaire assessing socio-demographic variables (8 items), psychosocial variables (6 items), environmental variables (10 items) and transport mode (4 types) and duration to work/other destinations...
2017: PloS One
https://www.readbyqxmd.com/read/28319149/walking-and-talking-the-tree-of-life-why-and-how-to-teach-about-biodiversity
#6
Cissy J Ballen, Harry W Greene
Taxonomic details of diversity are an essential scaffolding for biology education, yet outdated methods for teaching the tree of life (TOL), as implied by textbook content and usage, are still commonly employed. Here, we show that the traditional approach only vaguely represents evolutionary relationships, fails to denote major events in the history of life, and relies heavily on memorizing near-meaningless taxonomic ranks. Conversely, a clade-based strategy-focused on common ancestry, monophyletic groups, and derived functional traits-is explicitly based on Darwin's "descent with modification," provides students with a rational system for organizing the details of biodiversity, and readily lends itself to active learning techniques...
March 2017: PLoS Biology
https://www.readbyqxmd.com/read/28319133/effects-of-sudden-walking-perturbations-on-neuromuscular-reflex-activity-and-three-dimensional-motion-of-the-trunk-in-healthy-controls-and-back-pain-symptomatic-subjects
#7
Juliane Mueller, Tilman Engel, Steffen Mueller, Josefine Stoll, Heiner Baur, Frank Mayer
BACKGROUND: Back pain patients (BPP) show delayed muscle onset, increased co-contractions, and variability as response to quasi-static sudden trunk loading in comparison to healthy controls (H). However, it is unclear whether these results can validly be transferred to suddenly applied walking perturbations, an automated but more functional and complex movement pattern. There is an evident need to develop research-based strategies for the rehabilitation of back pain. Therefore, the investigation of differences in trunk stability between H and BPP in functional movements is of primary interest in order to define suitable intervention regimes...
2017: PloS One
https://www.readbyqxmd.com/read/28318998/commentary-on-primary-stenting-of-the-superficial-femoral-artery-in-intermittent-claudication-improves-health-related-quality-of-life-ankle-brachial-index-and-walking-distance-12-month-results-of-a-controlled-randomised-multicentre-trial
#8
https://www.readbyqxmd.com/read/28318988/analgesic-effects-of-morphine-and-butorphanol-in-broiler-chickens
#9
Preet M Singh, Craig B Johnson, Brett Gartrell, Sheryl Mitchinson, Antony Jacob, Paul Chambers
OBJECTIVE: To evaluate analgesic efficacies of morphine and butorphanol in lame broiler chickens. STUDY DESIGN: Double blind, randomized, controlled experimental study. ANIMALS: In study 1, 36 lame and 36 sound chickens. In study 2, 48 lame and 48 sound chickens. METHODS: Sound and lame chickens were gait scored and randomly assigned into four groups: sound-drug, sound-placebo, lame-drug, and lame-placebo in study 1...
January 11, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28318816/use-of-electromyography-to-optimize-lokomat-%C3%A2-settings-for-subject-specific-gait-rehabilitation-in-post-stroke-hemiparetic-patients-a-proof-of-concept-study
#10
Yosra Cherni, Mickael Begon, Hicham Chababe, Florent Moissenet
OBJECTIVES: While generic protocols exist for gait rehabilitation using robotic orthotics such as the Lokomat(®), several settings - guidance, body-weight support (BWS) and velocity - may be adjusted to individualize patient training. However, no systematic approach has yet emerged. Our objective was to assess the feasibility and effects of a systematic approach based on electromyography to determine subject-specific settings with application to the strengthening of the gluteus maximus muscle in post-stroke hemiparetic patients...
March 16, 2017: Neurophysiologie Clinique, Clinical Neurophysiology
https://www.readbyqxmd.com/read/28318630/sarcopenia-and-its-individual-criteria-are-associated-in-part-with-mortality-among-patients%C3%A2-on-hemodialysis
#11
Piyawan Kittiskulnam, Glenn M Chertow, Juan J Carrero, Cynthia Delgado, George A Kaysen, Kirsten L Johansen
The relative importance of sarcopenia and its individual components as independent predictors of mortality in the dialysis population has not been determined. We estimated whole-body muscle mass using pre-dialysis bioimpedance spectroscopy measurements in 645 ACTIVE/ADIPOSE-enrolled prevalent hemodialysis patients from San Francisco and Atlanta. Low muscle mass was defined as two standard deviations below sex-specific means for young adults from NHANES and indexed to height(2), body weight, body surface area, or body mass index...
March 16, 2017: Kidney International
https://www.readbyqxmd.com/read/28318502/efficacy-of-virtual-reality-in-pedestrian-safety-research
#12
Shuchisnigdha Deb, Daniel W Carruth, Richard Sween, Lesley Strawderman, Teena M Garrison
Advances in virtual reality technology present new opportunities for human factors research in areas that are dangerous, difficult, or expensive to study in the real world. The authors developed a new pedestrian simulator using the HTC Vive head mounted display and Unity software. Pedestrian head position and orientation were tracked as participants attempted to safely cross a virtual signalized intersection (5.5 m). In 10% of 60 trials, a vehicle violated the traffic signal and in 10.84% of these trials, a collision between the vehicle and the pedestrian was observed...
March 16, 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/28318394/effect-of-foot-and-ankle-immobilization-on-able-bodied-gait-as-a-model-to-increase-understanding-about-bilateral-transtibial-amputee-gait
#13
Antonia Nepomuceno, Matthew J Major, Rebecca Stine, Steven Gard
BACKGROUND: The anatomical foot-ankle complex facilitates advancement of the stance limb through foot rockers and late-stance power generation during walking, but this mechanism is altered for persons with bilateral transtibial amputation when using passive prostheses. OBJECTIVES: To study the effects of bilateral foot and ankle immobilization on able-bodied gait to serve as a model for understanding gait of persons with bilateral transtibial amputation and associated compensatory mechanisms...
March 1, 2017: Prosthetics and Orthotics International
https://www.readbyqxmd.com/read/28318262/fluorescent-copper-probe-inhibiting-a%C3%AE-1-16-copper-ii-catalyzed-intracellular-reactive-oxygen-species-production
#14
Gulshan R Walke, Dnyanesh S Ranade, Shefali N Ramteke, Srikanth Rapole, Cristina Satriano, Enrico Rizzarelli, Gaetano A Tomaselli, Giuseppe Trusso Sfrazzetto, Prasad P Kulkarni
A variety of fluorescent probes are proposed to monitor the intracellular copper content. So far, none of the probes have been evaluated for their potential to inhibit copper-associated intracellular oxidative stress. Herein, we studied the ability of a fluorescent copper probe, OBEP-CS1, to inhibit intracellular oxidative stress associated with an amyloid β (Aβ) peptide-copper complex. The data showed that OBEP-CS1 completely inhibits the copper-catalyzed oxidation as well as decarboxylation/deamination of Aβ1-16...
March 20, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28317554/chimpanzee-and-human-midfoot-motion-during-bipedal-walking-and-the-evolution-of-the-longitudinal-arch-of-the-foot
#15
Nicholas B Holowka, Matthew C O'Neill, Nathan E Thompson, Brigitte Demes
The longitudinal arch of the human foot is commonly thought to reduce midfoot joint motion to convert the foot into a rigid lever during push off in bipedal walking. In contrast, African apes have been observed to exhibit midfoot dorsiflexion following heel lift during terrestrial locomotion, presumably due to their possession of highly mobile midfoot joints. This assumed dichotomy between human and African ape midfoot mobility has recently been questioned based on indirect assessments of in vivo midfoot motion, such as plantar pressure and cadaver studies; however, direct quantitative analyses of African ape midfoot kinematics during locomotion remain scarce...
March 2017: Journal of Human Evolution
https://www.readbyqxmd.com/read/28317387/board-walk
#16
Mamoru Shibata, R Allan Purdy
No abstract text is available yet for this article.
March 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28317385/does-perceived-safety-modify-the-effectiveness-of-a-walking-group-intervention-designed-to-promote-physical-activity
#17
Jamila L Kwarteng, Amy J Schulz, Graciela B Mentz, Barbara A Israel, Trina R Shanks, Denise White Perkins
PURPOSE: To examine whether perceived safety modified the effectiveness of the Walk Your Heart to Health (WYHH) intervention in promoting physical activity and reducing central adiposity in predominantly non-Latino black (henceforth black) and Latino communities. DESIGN: Generalized estimation equations were used to assess modifying effects of perceived safety on the route and perceived neighborhood safety on (1) WYHH participation at 8 weeks and 32 weeks, (2) associations between participation and physical activity, and (3) associations between physical activity and central adiposity...
January 1, 2017: American Journal of Health Promotion: AJHP
https://www.readbyqxmd.com/read/28317236/rehabilitation-of-revision-total-hip-replacement-a-multi-centre-survey-of-current-practice
#18
Meredith Newman, Karen Barker
BACKGROUND: Demand for revision total hip replacement (RTHR) is increasing. Outcomes after RTHR are varied, with reasonable pain relief but smaller gains in function and mobility. Whether sub-optimal rehabilitation contributes to poorer functional outcomes is unclear. Current rehabilitation is not well defined and there is little research into RTHR rehabilitation. AIMS AND OBJECTIVES: To gather information about the current rehabilitation of patients undergoing planned, single-stage revision or re-revision THR surgery...
March 20, 2017: Musculoskeletal Care
https://www.readbyqxmd.com/read/28316965/surgical-outcomes-of-biologic-fixation-for-subtrochanteric-fracture-using-locking-compression-plates
#19
Jae Hoon Jang, Jae Min Ahn, Hee Jin Lee, Nam Hoon Moon
PURPOSE: This study aimed to evaluate the surgical outcomes of biologic plating using locking compression plate-distal femur (LCP-DF) in patients with subtrochanteric fracture of the femur. MATERIALS AND METHODS: Between January 2010 and December 2013, 28 consecutive patients with subtrochanteric fractures of the femur, treated with biologic fixation using LCP-DF, were enrolled. Preoperative values, including patient age, sex, body mass index, fracture type, type of lung injury, and surgical timing from injury to surgery, were retrospectively evaluated...
March 2017: Hip & Pelvis
https://www.readbyqxmd.com/read/28316964/the-fixation-method-according-to-the-fracture-type-of-the-greater-trochanter-in-unstable-intertrochanteric-fractures-undergoing-arthroplasty
#20
Doohoon Sun, Byeong-Seop Park, Gun-Il Jang, Bongjoo Lee
PURPOSE: We conducted a study on patients who underwent hip joint arthroplasty because of unstable femur intertrochanteric fractures with greater trochanter bony fragments. After dividing patients into three groups depending on their fracture patterns, we evaluated the clinical and radiological outcomes of different operation methods applied to each of these groups. MATERIALS AND METHODS: Using Evan's classification, we defined an unstable intertrochanteric fracture as those characterized as stage 4 or 5...
March 2017: Hip & Pelvis
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