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https://www.readbyqxmd.com/read/29782844/evaluation-of-the-serum-ionic-fluoride-concentration-as-a-biomarker-of-bone-metabolism-post-spinal-fusion-surgery
#1
Ryosuke Oikawa, Yuji Fujita, Hideki Murakami, Hirooki Endo, Daisuke Yamabe, Yusuke Chiba, Yuichiro Abe, Minoru Doita
BACKGROUND: Bone union after spinal fusion surgery with instrumentation has been determined only with imaging studies. We evaluated the usefulness of the serum ionic fluoride (SIF) concentration as a biomarker of the bone union status. METHODS: We enrolled 25 patients who underwent spinal surgery in our institution, and we divided patients into three groups with and without instrumentation (G1, G2, and G3). We collected the fasting serum level preoperatively and on day 1 (D1), week 1 (D7), week 2 (D14), month 1 (D30), month 3 (D90), and month 6 (D180) postoperatively, and measured SIF concentrations using the flow injection method with an ion-selective electrode...
May 18, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29781944/early-comparative-outcomes-of-carbon-fiber-reinforced-polymer-plate-in-the-fixation-of-distal-femur-fractures
#2
Phillip M Mitchell, Adam K Lee, Cory A Collinge, Bruce H Ziran, Kate G Hartley, A Alex Jahangir
OBJECTIVE: To evaluate the early clinical results of distal femur fractures treated with carbon fiber reinforced - polyetheretherketone (CFR-PEEK) plates compared to stainless steel (SS) lateral locking plates. DESIGN: Retrospective comparative cohort study SETTING:: ACS Level I trauma center. PATIENTS/PARTICIPANTS: Twenty-two patients (11 SS, 11 CFR-PEEK) with closed distal femur fractures treated by a single surgeon over a 6-year period...
May 16, 2018: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/29781787/evaluating-the-duration-of-prophylactic-post-operative-antibiotic-agents-after-open-reduction-internal-fixation-for-closed-fractures
#3
Brett D Crist, Lasun O Oladeji, Gregory J Della Rocca, David A Volgas, James P Stannard, David D Greenberg
BACKGROUND: The importance of timely pre-operative antibiotic agents for effective surgical prophylaxis has been established but the optimal duration of antimicrobial coverage post-operatively has not yet been defined clearly. The purpose of this study was to determine if prophylactic post- operative cefazolin for 23 hours decreases the risk of surgical site infection (SSI) after open reduction internal fixation (ORIF) of closed extremity fractures. PATIENTS AND METHODS: After Institutional Reviews Board approval, patients undergoing ORIF of closed extremity fractures who had a planned post-operative stay of at least 23 hours were randomly assigned to either receive 23 hours of cefazolin or a placebo...
May 21, 2018: Surgical Infections
https://www.readbyqxmd.com/read/29781706/launch-of-an-infrastructure-for-health-research-bbmri-eric
#4
Jan-Eric Litton
Biobanking and BioMolecular resources Research Infrastructure (BBMRI)- European Research Infrastructure Consortium (ERIC) is the largest infrastructure launched in Europe in health research. By nature it is a distributed infrastructure, in which biological samples and data are hosted by the European Member States biobanks. As of today, BBMRI-ERIC consists of 19 European Member States and 1 international organization, the International Agency for Research on Cancer. This means that BBMRI-ERIC has a population of >500 million individuals in Europe...
May 21, 2018: Biopreservation and Biobanking
https://www.readbyqxmd.com/read/29781316/fas-and-fasl-genetic-polymorphisms-in-women-with-recurrent-pregnancy-loss-a-case-control-study
#5
Ae Ra Han, Young Min Choi, Min A Hong, Jin Ju Kim, Sung Ki Lee, Kwang Moon Yang, Eun Chan Paik, Hyeon Jeong Jeong, Jong Kwan Jun
Aberrant apoptosis at the trophoblast-maternal interface and abnormal expression of Fas and Fas ligand (FasL) have been reported in complicated pregnancies with recurrent pregnancy losses (RPL) and preeclampsia. We assessed the prevalence of Fas and FasL genetic polymorphisms in Korean women with RPL and in fertile controls. In total, 306 women with RPL and 298 fertile controls were enrolled. Genotype distributions of Fas and FasL in RPL patients versus fertile controls were examined under the Hardy-Weinberg equilibrium...
May 20, 2018: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/29781108/an-exploratory-study-of-sectra-table-visualization-improves-the-effectiveness-of-emergency-bedside-echocardiography-training
#6
Di Shi, Joseph H Walline, Jihai Liu, Xuezhong Yu, Jun Xu, Priscilla P Song, Huadong Zhu, John M O'Donnell
OBJECTIVES: Echocardiography is an essential tool in emergency medicine, and its training is the most challenging of all types of bedside ultrasound (US) training. This study investigated the effectiveness of the Sectra Table (Sectra AB, Linköping, Sweden), an anatomy visualization and collaboration tool, in improving the quality of echocardiography training for emergency medicine physicians. METHODS: We conducted an exploratory prospective observational study from 2015 to 2017 and enrolled 66 trainees who participated in a 2...
May 21, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29780889/how-to-conceptualize-and-implement-a-phd-program-in-health-sciences-the-basel-approach
#7
Franziska Keller, Suzanne Dhaini, Matthias Briel, Sina Henrichs, Christoph Höchsmann, Daniel Kalbermatten, Nino Künzli, Annette Mollet, Christian Puelacher, Arno Schmidt-Trucksäss, Belinda von Niederhäusern, Sabina De Geest
Objectives: Over the past decade, several excellent guidelines have been published on how to enhance the quality of PhD education in Europe. Aimed primarily at preparing students for innovative roles in their fields, they include variously structured approaches to curricular offerings, as well as other program components applicable across specialties (eg: supervisor support, scientific conduct, transferable skills). Since 2012, the interdisciplinary PhD Program in Health Sciences (PPHS) at the Faculty of Medicine of the University of Basel in Switzerland has focused on translating these guidelines into a 21st-century health sciences PhD program...
January 2018: Journal of Medical Education and Curricular Development
https://www.readbyqxmd.com/read/29780801/recovering-the-original-intentions-of-risk-assessment-and-management-of-genetically-modified-organisms-in-the-european-union
#8
Dennis Eriksson
No abstract text is available yet for this article.
2018: Frontiers in Bioengineering and Biotechnology
https://www.readbyqxmd.com/read/29780767/effectiveness-of-a-multicomponent-school-based-intervention-to-reduce-bullying-among-adolescents-in-chandigarh-north-india-a-quasi-experimental-study-protocol
#9
Monica Rana, Madhu Gupta, Prahbhjot Malhi, Sandeep Grover, Manmeet Kaur
Background: Bullying perpetration and victimization is associated with significant academic, psychosocial and health related problems among adolescents. There is a need to develop effective interventions to prevent bullying among adolescents, especially in low and middle income countries. This paper presents the study protocol to develop, and evaluate the effect of multi-component school based prevention program for bullying in India. Design: Quasi-experimental study...
February 5, 2018: Journal of Public Health Research
https://www.readbyqxmd.com/read/29780239/patient-reported-outcomes-in-european-spondyloarthritis-patients-a-systematic-review-of-the-literature
#10
REVIEW
Juan Carlos Torre-Alonso, Rubén Queiro, Marta Comellas, Luís Lizán, Carles Blanch
Objective: This review aims to summarize the current literature on patient-reported outcomes (PROs) in spondyloarthritis (SpA). Patients and methods: We performed a systematic literature review to identify studies (original articles and narrative and systematic reviews) regarding PROs (health-related quality of life [HRQoL], satisfaction, preferences, adherence/compliance, and persistence) in SpA patients published in the European Union through December 2016. International databases (Medline/PubMed, Cochrane Library, ISI Web of Knowledge, Scopus) were searched using keywords in English...
2018: Patient Preference and Adherence
https://www.readbyqxmd.com/read/29780078/work-related-injuries-and-fatalities-in-the-geotechnical-site-works
#11
Özge Akboğa Kale, Tuğba Eskişar
Geotechnical site works are comprehensive, and they constitute the first step of the construction process. This study performs data mining of geotechnical works and analyzes the database for the root causes of accidents. The Occupational Safety and Health Administration (OSHA) was chosen for the 1984-2013 time frame with 247 cases. Descriptive statistical analyses were performed to discuss variables such as the end use of the work, project type and cost, soil type and condition, type and degree of injury, cause and type of accident, unsafe acts, and occupation and union status of the victim...
May 19, 2018: Industrial Health
https://www.readbyqxmd.com/read/29779968/one-stage-posterior-debridement-and-fusion-combined-with-irrigation-and-drainage-for-the-treatment-of-postoperative-lumbar-spondylodiscitis
#12
Tao Zhang, Jianzhong Hu, Jianhuang Wu, Jinyang Liu, Shuangfei Ni, Chunyue Duan
OBJECTIVE: The aim of this study was to evaluate the clinical outcomes of one-stage posterior debridement, interbody fusion, and instrumentation, combined with irrigation and drainage, for treating lumbar spondylodiscitis. METHODS: The study included 23 patients (13 male and 10 female, mean age: 45 years) who had posterior debridement, interbody fusion, and instrumentation, followed by continuous closed irrigation and drainage for lumbar postoperative spondylodiscitis...
May 17, 2018: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/29779917/antimicrobial-resistance-among-migrants-in-europe-a-systematic-review-and-meta-analysis
#13
Laura B Nellums, Hayley Thompson, Alison Holmes, Enrique Castro-Sánchez, Jonathan A Otter, Marie Norredam, Jon S Friedland, Sally Hargreaves
BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings...
May 17, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/29779321/-the-value-of-serum-heavy-light-chain-immunoassay-to-assess-therapeutic-response-in-patients-with-multiple-myeloma
#14
X C Yu, W Su, J L Zhuang
Objective: To assess the value of immunoglobulin heavy/light chain (HLC) immunoassay on therapeutic response in patients with multiple myeloma(MM). Methods: A total of 45 newly diagnosed MM patients were retrospectively enrolled in Peking Union Medical College Hospital from 2013 to 2016, whose 115 serum samples were consecutively collected. HLC was tested to evaluate response and compare with other methods for M protein detection. Results: ①There were 30 males and 15 females in total of whom the monoclonal immunoglobulin was IgG in 27 (IgGκ∶IgGλ 12∶15) and IgA (IgAκ∶IgAλ 9∶9) in 18...
April 14, 2018: Zhonghua Xue Ye Xue za Zhi, Zhonghua Xueyexue Zazhi
https://www.readbyqxmd.com/read/29779053/non-union-rate-of-type-ii-and-iii-odontoid-fractures-in-cppd-versus-a-control-population
#15
Aaron Wold, Jonelle Petscavage-Thomas, Eric A Walker
OBJECTIVE: The objective was to determine if there is a significant difference between rates of non-union of type II and III odontoid fractures in patients with calcium pyrophosphate dihydrate deposition (CPPD) compared with a control population. MATERIALS AND METHODS: A 10-year retrospective picture archive and communications system review was performed of 31 CPPD patients and 31 control patients. Imaging studies were reviewed for radiographic or CT evidence of osseous union and complications...
May 19, 2018: Skeletal Radiology
https://www.readbyqxmd.com/read/29778681/portable-x-ray-fluorescence-for-the-detection-of-pop-bfrs-in-waste-plastics
#16
Martin Sharkey, Mohamed Abou-Elwafa Abdallah, Daniel S Drage, Stuart Harrad, Harald Berresheim
The purpose of this study was to establish the efficacy of portable X-ray fluorescence (XRF) instrumentation as a screening tool for a variety of end of life plastics which may contain excess amounts of brominated flame retardants (BFRs), in compliance with European Union (EU) and United Nations Environment Programme (UNEP) legislative limits (low POP concentration limits - LPCLs). 555 samples of waste plastics were collected from eight waste and recycling sites in Ireland, including waste electrical and electronic equipment (WEEE), textiles, polyurethane foams (PUFs), and expanded polystyrene foams...
May 17, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29778498/validation-on-milk-and-sprouts-of-en-iso-16654-2001-microbiology-of-food-and-animal-feeding-stuffs-horizontal-method-for-the-detection-of-escherichia-coli-o157
#17
Rosangela Tozzoli, Antonella Maugliani, Valeria Michelacci, Fabio Minelli, Alfredo Caprioli, Stefano Morabito
In 2006, the European Committee for standardisation (CEN)/Technical Committee 275 - Food analysis - Horizontal methods/Working Group 6 - Microbiology of the food chain (TC275/WG6), launched the project of validating the method ISO 16654:2001 for the detection of Escherichia coli O157 in foodstuff by the evaluation of its performance, in terms of sensitivity and specificity, through collaborative studies. Previously, a validation study had been conducted to assess the performance of the Method No 164 developed by the Nordic Committee for Food Analysis (NMKL), which aims at detecting E...
May 8, 2018: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/29778396/how-effective-are-approaches-to-migrant-screening-for-infectious-diseases-in-europe-a-systematic-review
#18
REVIEW
Farah Seedat, Sally Hargreaves, Laura B Nellums, Jing Ouyang, Michael Brown, Jon S Friedland
Rates of migration to Europe, and within Europe, have increased in recent years, with considerable implications for health systems. Migrants in Europe face a disproportionate burden of tuberculosis, HIV, and hepatitis B and C, yet experience a large number of barriers to accessing statutory health care on arrival. A better understanding of how to deliver effective and cost-effective screening, vaccination, and health services to this group is now crucial. We did a systematic review to document and assess the effectiveness and cost-effectiveness of approaches used for infectious diseases screening, and to explore facilitators and barriers experienced by migrants to accessing screening programmes...
May 16, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/29778330/lymph-node-metastasis-in-thymic-malignancies-a-chinese-multicenter-prospective-observational-study
#19
Wentao Fang, Yun Wang, Liewen Pang, Zhitao Gu, Yucheng Wei, Yongyu Liu, Peng Zhang, Chun Chen, Xinming Zhou, Yangchun Liu, Keneng Chen, Jianyong Ding, Yongtao Han, Yin Li, Zhentao Yu, Yuan Liu, Jianhua Fu
OBJECTIVES: To study the incidence and pattern of lymph node metastases in thymic malignancies. METHODS: This multicenter prospective observational trial with intentional lymph node dissection was carried out by the Chinese Alliance for Research in Thymomas (ChART). Data on patients with thymic tumors without pretreatment were collected prospectively. Results from this prospective study were then compared with those from a previously reported ChART retrospective study...
April 18, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29777778/anterior-approach-in-humeral-plating-osteosynthesis
#20
Daniel Handy Eone, Prudence Christelle Danielle Ngono, Marie Josée Essi, Gaël Leckpa, Kennedy Olivier Muluem, Farikou Ibrahima, Maurice Aurélien Sosso
CONTEXT: Humeral plating osteosynthesis is controversial, particularly regarding the choice between anterior and lateral approach, data for which in the context of a low-income country are lacking. HYPOTHESIS: The anterior approach is an easy surgical technique, allowing good anatomic reconstruction. We hypothesize that the anterior approach is associated with fewer neurovascular lesions and functional sequelae than the lateral approach. MATERIALS AND METHODS: A retrospective study with assessment update was carried out over a period of 6 years 4 months from January 2010 to June 2016, with consecutive recruitment in the city of Yaoundé, Cameroon...
May 16, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
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