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https://www.readbyqxmd.com/read/28926814/one-year-persistence-of-individual-gait-patterns-identified-in-a-follow-up-study-a-call-for-individualised-diagnose-and-therapy
#1
F Horst, M Mildner, W I Schöllhorn
Although a hunch about the individuality of human movements generally exists, differences in gait patterns between individuals are often neglected. To date, only a few studies distinguished individual gait patterns in terms of uniqueness and emphasised the relevance of individualised diagnoses and therapy. However, small sample sizes have been a limitation on identifying subjects based on gait patterns, and little is known about the permanence of subject-specific characteristics over time. The purpose of this study was (1) to prove the uniqueness of individual gait patterns within a larger sample and (2) to prove the long-term permanence of individual gait patterns...
September 6, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28926704/chromatographic-properties-of-minimal-aspect-ratio-monolithic-silica-columns
#2
Takeshi Hara, Shunta Futagami, Wim De Malsche, Sebastiaan Eeltink, Herman Terryn, Gino V Baron, Gert Desmet
We report on a study wherein we synthesized TMOS-based silica monolithic skeletons in capillaries with an i.d. of 5 and 10 μm to produce skeleton structures with very low capillary-to-domain size aspect-ratios. These structures include the absolute minimal aspect-ratio case of a monolithic structure whose cross-section only contains a single node point. With domain-sized based reduced plate heights running as low as hmin = 1.3-1.5 for retained coumarin dyes providing a retention factor of k = 0.6-1.0, the study confirms the classic observation that ultra-low aspect ratio columns generate a markedly lower dispersion than columns with a larger aspect ratio made in the past by Knox, Jorgenson and Kennedy for the packed bed of spheres, but now for silica monoliths...
September 19, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28926635/a-comparison-of-running-kinetics-in-children-with-and-without-genu-varus-a-cross-sectional-study
#3
Amir Ali Jafarnezhadgero, Morteza Madadi Shad, Mahdi Majlesi, Urs Granacher
INTRODUCTION: Varus knee alignment has been identified as a risk factor for the progression of medial knee osteoarthritis. However, the underlying mechanisms have not been elucidated yet in children. Thus, the aims of the present study were to examine differences in ground reaction forces, loading rate, impulses, and free moment values during running in children with and without genu varus. METHODS: Thirty-six boys aged 9-14 volunteered to participate in this study...
2017: PloS One
https://www.readbyqxmd.com/read/28926609/developmental-expression-of-membrane-type-4-matrix-metalloproteinase-mt4-mmp-mmp17-in-the-mouse-embryo
#4
María José Blanco, Iván Rodríguez-Martín, Ana I R Learte, Cristina Clemente, María Gregoria Montalvo, Motoharu Seiki, Alicia G Arroyo, Cristina Sánchez-Camacho
Matrix metalloproteinases (MMPs) constitute a large group of endoproteases that play important functions during embryonic development, tumor metastasis and angiogenesis by degrading components of the extracellular matrix. Within this family, we focused our study on Mt4-mmp (also called Mmp17) that belongs to a distinct subset that is anchored to the cell surface via a glycosylphosphatidylinositol (GPI) moiety and with the catalytic site exposed to the extracellular space. Information about its function and substrates is very limited to date, and little has been reported on its role in the developing embryo...
2017: PloS One
https://www.readbyqxmd.com/read/28926471/role-of-fat-soluble-vitamins-in-osteoarthritis-management
#5
Xiao-Yan Zheng, Jun Liang, Yu-Sheng Li, Min Tu
Osteoarthritis (OA) is a chronic degenerative joint disease, in which metabolic imbalance in bone is observed. The pathological mechanism of metabolic imbalance is not clear yet, but the nutritional factors, particularly the vitamins, might be intrinsic to the development and progression of OA. In this review article, we have explored databases such as PubMed, Scopus, and Google Scholar articles until the beginning of 2017 and reviewed the role of fat-soluble vitamins in pathological and therapeutic aspects of OA...
September 19, 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/28926221/fourier-transform-ms-and-closed-path-multi-reflection-time-of-flight-ms-using-an-electrostatic-linear-ion-trap
#6
Eric T Dziekonski, Joshua T Johnson, Kenneth W Lee, Scott A McLuckey
An electrostatic linear ion trap (ELIT) has been configured to allow for the simultaneous acquisition of mass spectra via Fourier transform (FT) techniques (frequency measurement) and via time-of-flight (TOF) (time measurement). In the former case, the time-domain image charge derived from a pick-up electrode in the field-free region of the ELIT is converted to frequency-domain data via Fourier transformation (i.e., FT-ELIT MS). In the latter case, the time difference between ion injection into the ELIT and ion detection after release from the ELIT using a micro-channel plate (MCP) enables the acquisition of multi-reflection time-of-flight mass spectra (MR-TOF MS)...
September 19, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28925539/expression-and-functional-proteomic-analyses-of-osteocytes-from-xenopus-laevis-tested-under-mechanical-stress-conditions-preliminary-observations-on-an-appropriate-new-animal-model
#7
Jessika Bertacchini, Marta Benincasa, Marta Checchi, Francesco Cavani, Alberto Smargiassi, Marzia Ferretti, Carla Palumbo
Hitherto, the role of the osteocyte as transducer of mechanical stimuli into biological signals is far from settled. In this study, we used an appropriate model represented by the cortex of Xenopus laevis long bone diaphysis lacking (unlike the mammalian one) of vascular structures and containing only osteocytes inside the bone matrix. These structural features allow any change of protein profile that might be observed upon different experimental conditions, such as bone adaptation to stress/mechanical loading, to be ascribed specifically to osteocytes...
September 19, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28924613/ligand-induced-twisting-of-nanoplatelets-and-their-self-assembly-into-chiral-ribbons
#8
Santanu Jana, Marta de Frutos, Patrick Davidson, Benjamin Abécassis
The emergence of chirality is a central issue in chemistry, materials science, and biology. In nanoparticle assemblies, chirality has been shown to arise through a few different processes, but chiral organizations composed of plate-like nanoparticles, a class of material under scrutiny due to their wide applicative potential, have not yet been reported. We show that ribbons of stacked board-shaped cadmium selenide (CdSe) nanoplatelets (NPLs) twist upon the addition of oleic acid ligand, leading to chiral ribbons that reach several micrometers in length and display a well-defined pitch of ~400 nm...
September 2017: Science Advances
https://www.readbyqxmd.com/read/28924611/size-effects-resolve-discrepancies-in-40-years-of-work-on-low-temperature-plasticity-in-olivine
#9
Kathryn M Kumamoto, Christopher A Thom, David Wallis, Lars N Hansen, David E J Armstrong, Jessica M Warren, David L Goldsby, Angus J Wilkinson
The strength of olivine at low temperatures and high stresses in Earth's lithospheric mantle exerts a critical control on many geodynamic processes, including lithospheric flexure and the formation of plate boundaries. Unfortunately, laboratory-derived values of the strength of olivine at lithospheric conditions are highly variable and significantly disagree with those inferred from geophysical observations. We demonstrate via nanoindentation that the strength of olivine depends on the length scale of deformation, with experiments on smaller volumes of material exhibiting larger yield stresses...
September 2017: Science Advances
https://www.readbyqxmd.com/read/28924331/relative-range-error-evaluation-of-terrestrial-laser-scanners-using-a-plate-a-sphere-and-a-novel-dual-sphere-plate-target
#10
Bala Muralikrishnan, Prem Rachakonda, Vincent Lee, Meghan Shilling, Daniel Sawyer, Geraldine Cheok, Luc Cournoyer
Terrestrial laser scanners (TLS) are a class of 3D imaging systems that produce a 3D point cloud by measuring the range and two angles to a point. The fundamental measurement of a TLS is range. Relative range error is one component of the overall range error of TLS and its estimation is therefore an important aspect in establishing metrological traceability of measurements performed using these systems. Target geometry is an important aspect to consider when realizing the relative range tests. The recently published ASTM E2938-15 mandates the use of a plate target for the relative range tests...
December 2017: Measurement Science & Technology
https://www.readbyqxmd.com/read/28924002/variations-in-infant-and-childhood-vitamin-d-supplementation-programs-across-europe-and-factors-influencing-adherence
#11
Suma Uday, Ardita Kongjonaj, Magda Aguiar, Ted Tulchinsky, Wolfgang Hoegler
BACKGROUND: Nutritional rickets is a growing global public health concern despite existing prevention programs and health policies. We aimed to compare infant and childhood vitamin D supplementation policies, implementation strategies and practices across Europe and explore factors influencing adherence. METHODS: European Society for Paediatric Endocrinology Bone and Growth Plate Working Group members and other specialists completed a questionnaire on country-specific vitamin D supplementation policy and child healthcare programs, socioeconomic factors, policy implementation strategies, and adherence...
September 18, 2017: Endocrine Connections
https://www.readbyqxmd.com/read/28923874/agar-based-screening-for-azole-resistance-in-aspergillus-fumigatus-using-vipcheck%C3%A2-a-single-centre-evaluation
#12
J B Buil, H A L van der Lee, A J M M Rijs, J Zoll, J A M F Hovestadt, W J G Melchers, P E Verweij
Introduction Antifungal susceptibility testing is an essential tool for guiding therapy, although EUCAST and CLSI reference methods are often only available in specialized centres. We studied the performance of an agar-based screening method for the detection of azole resistance in Aspergillus fumigatus cultures.Methods The VIPcheck™ consists of four wells containing voriconazole, itraconazole, posaconazole or a growth control. Ninety-six A. fumigatus isolates were used. Thirty-three isolates harboured a known resistance mechanism: TR34/L98H (11 isolates); TR46/Y121F/T289A (6 isolates); TR53 (2 isolates) and fourteen isolates with other cyp51A-gene point mutations...
September 18, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28923661/the-influence-of-the-aquatic-environment-on-the-center-of-pressure-impulses-and-upper-and-lower-trunk-accelerations-during-gait-initiation
#13
Andresa R Marinho-Buzelli, Kei Masani, Hossein Rouhani, Ana M Barela, Gustavo T B Fernandes, Mary C Verrier, Milos R Popovic
Gait initiation is defined as the transition from stationary standing to steady-state walking. Despite the frequent use of therapy pools for training walking in early stages of rehabilitation, none have been reported on the effects of immersion on gait initiation. We aimed to analyze the center of pressure (COP) trajectories, the vertical and anteroposterior impulses and upper and lower trunk accelerations during anticipatory (APA) and execution phases of gait initiation. In the COP trajectory, the execution (EXE) phase was further subdivided in two phases: predominantly mediolateral (EXE1), and predominantly anteroposterior (EXE2)...
September 8, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28923547/how-oral-environment-simulation-affects-ceramic-failure-behavior
#14
Ediléia Lodi, Kátia R Weber, Paula Benetti, Pedro H Corazza, Álvaro Della Bona, Márcia Borba
STATEMENT OF PROBLEM: Investigating the mechanical behavior of ceramics in a clinically simulated scenario contributes to the development of new and tougher materials, improving the clinical performance of restorations. The optimal in vitro environment for testing is unclear. PURPOSE: The purpose of this in vitro study was to investigate the failure behavior of a leucite-reinforced glass-ceramic under compression loading and fatigue in different simulated oral environment conditions...
September 16, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28923077/development-and-evaluation-of-an-efficient-heterologous-gene-knock-in-reporter-system-in-lactococcus-lactis
#15
Yifei Lu, Hongxiang Yan, Jiezhong Deng, Zhigang Huang, Xurui Jin, Yanlan Yu, Qiwen Hu, Fuquan Hu, Jing Wang
BACKGROUND: Lactococcus lactis is a food grade probiotics and widely used to express heterologous proteins. Generally, target genes are knocked into the L. lactis genome through double-crossover recombination to express heterologous proteins stably. However, creating marker-less heterologous genes knocked-in clones is laborious. In this study, an efficient heterologous gene knock-in reporter system was developed in L. lactis NZ9000. RESULTS: Our knock-in reporter system consists of a temperature-sensitive plasmid pJW and a recombinant L...
September 18, 2017: Microbial Cell Factories
https://www.readbyqxmd.com/read/28923047/prepubertal-onset-of-slipped-capital-femoral-epiphysis-associated-with-hypothyroidism-a-case-report-and-literature-review
#16
Saori Kadowaki, Tomohiro Hori, Hideki Matsumoto, Kaori Kanda, Michio Ozeki, Yu Shirakami, Norio Kawamoto, Hidenori Ohnishi, Toshiyuki Fukao
BACKGROUND: Slipped capital femoral epiphysis (SCFE) is a common hip disorder characterized by displacement of the capital femoral epiphysis from the metaphysic through the femoral epiphyseal plate. SCFE usually occurs during puberty, with obesity a common risk factor. We experienced a rare case of SCFE associated with hypothyroidism in a prepubescent patient who was not obese. CASE PRESENTATION: The patient was an 8-year-old boy suffering from bilateral SCFE with hypothyroidism...
September 18, 2017: BMC Endocrine Disorders
https://www.readbyqxmd.com/read/28922808/the-discovery-of-ceftazidime-avibactam-as-an-anti-mycobacterium-avium-agent
#17
Devyani Deshpande, Shashikant Srivastava, Moti L Chapagain, Pooi S Lee, Kayle N Cirrincione, Jotam G Pasipanodya, Tawanda Gumbo
Objectives: To determine if ceftaroline and ceftazidime combined with avibactam are efficacious against pulmonary Mycobacterium avium complex (MAC) disease. Methods: First, we performed a concentration-effect study of ceftaroline and ceftaroline/avibactam against extracellular MAC in test tubes. Given the difficulty of obtaining avibactam at the time of experimentation, we used a single concentration of commercial ceftazidime/avibactam, and two sets of non-treated controls, one with ceftazidime/avibactam and the other without...
September 1, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28922701/unicortical-and-bicortical-plating-in-the-fixation-of-comminuted-fractures-of-the-clavicle-a-biomechanical-study
#18
John M Looft, Lincoln Corrêa, Minoo Patel, Mathew Rawlings, David C Ackland
BACKGROUND: Intraoperative neurovascular complications with clavicle fracture fixation are often due to far cortex penetration by drills and screws, but could be avoided using a unicortical construct. The objective of this study was to compare the bending and torsional strength of a unicortical locking screw plate construct and a hybrid (with central locked and outer non-locked long oblique screws) unicortical plate construct for clavicle fracture fixation with that of a conventional bicortical locking screw construct of plate fixation...
September 18, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28922248/maxillary-corticotomies-with-bone-to-bone-retraction-and-mandibular-segmental-osteotomy-for-correcting-an-anterior-double-protrusion
#19
Kyung A Kim, Baek-Soo Lee, Ayse Selenge Akbulut, Seong-Hun Kim, Gerald Nelson
BACKGROUNDS: This article presents maxillary corticotomies with bone-to-bone retraction and anterior segmental osteotomy (ASO) as an alternative to 2-jaw orthognathics in the bimaxilary protrusion patient with partially anchylosed maxillary anterior tooth. METHODS: The 18-year-old male, complaining of anterior protrusion, with a trauma history to the maxillary central incisor, and requesting rapid treatment, was treated with maxillary corticotomies in 2 stages and ASO in the mandible...
September 15, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28922029/exploratory-study-into-the-microbiological-quality-of-spinach-and-cabbage-purchased-from-street-vendors-and-retailers-in-johannesburg-south-africa
#20
Erika M du Plessis, Sarasha Govender, Bala Pillay, Lise Korsten
Knowledge of the microbiological quality and prevalence of antibiotic resistance and virulence genes in bacterial isolates from leafy green vegetables supplied by formal suppliers (retailers) and informal suppliers (street vendors) in South Africa is limited. Because leafy vegetables have been implicated in foodborne disease outbreaks worldwide, 180 cabbage and spinach samples were collected from three major retailers and nine street vendors in Johannesburg, South Africa. Escherichia coli and coliforms were enumerated using Petrifilm plates...
September 18, 2017: Journal of Food Protection
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