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V V Mozharovsky, V M Misharin, A A Tsyganov, K V Mozharovsky
AIM: to study efficacy and safety of current laparoscopic techniques of cholecystectomy. MATERIAL AND METHODS: 3 groups of patients were defined. Single laparoscopic access with/without trocar support was used in group 1 (SILS+, n=10) and 2 (SILS, n=16) respectively. Conventional four-port laparoscopic cholecystectomy was applied in comparison group. RESULTS: SILS+ and SILS techniques were associated with less pain syndrome within first 12 hours after surgery compared with four-port cholecyst-ectomy...
2016: Khirurgiia
Joji Kawabe, Shigeaki Higashiyama, Kohei Kotani, Atsushi Yoshida, Naoyoshi Onoda, Susumu Shiomi
BACKGROUND: Radioiodine remnant ablation (RRA) is used to destroy residual normal thy- roid tissue after total thyroidectomy in differentiated thyroid carcinoma (DTC) patients. As 1,850 MBq RRA is routinely performed at our facility, we evaluated the outcomes. METHODS: Sixty-seven DTC patients without macroscopic residual lesions after total thyroid- ectomy were evaluated. Thyroglobulin (Tg) was measured 2-3 months before RRA with thyrox- in administration (pretreatment); just before ablation after a 3-week iodine intake restriction with thyroxin withdrawal (THW) (n = 16) or recombinant human thyroid-stimulating hormone (rhTSH) stimulation (n = 51); and 3 months after RRA after a 2-week iodine intake restriction and 3‒week THW (n = 57) or rhTSH stimulation (n = 10)...
April 29, 2016: Quarterly Journal of Nuclear Medicine and Molecular Imaging
O V Pikin, A B Ryabov, A Kh Trakhtenberg, V A Glushko, K I Kolbanov, A M Amiraliev, V V Barmin, Z G Tukvadze
AIM: Postoperative complications after pneumonectomy for NSCLC depend on the extension of surgery, comorbidities and accurate registration of any adverse event. The aim of the study was to evaluate the short-term results after standard and extended pneumonectomy in NSCLC patients according to the TMM grading system. MATERIAL AND METHODS: We included 216 NSCLC patients consecutively submitted to pneumonectomy at our institution from January 2009 to December 2013 in the retrospective study performed on data prospectively collected in an electronic clinical database...
2016: Khirurgiia
Nan Ge, Shupeng Wang, Sheng Wang, Guoxin Wang, Xiang Liu, Jintao Guo, Fei Yang, Wen Liu, Siyu Sun
An 85-year-old male patient with common bile duct stones and gallbladder stone was admitted to the hospital. Endoscopic ultrasound (EUS)-guided cholecystogastrostomy and the placement of a novel covered mental stent was performed after the endoscopic sphincter ectomy procedure. Two weeks later the stents were removed, and an endoscope was advanced into the gallbladder via the fistula, and cholecystolithotomy was performed. For weeks later gallbladder was assessed by abdominal ultrasound. EUS-guided cholecystogastrostomy with mental stent deployment was successfully performed...
April 2015: Endoscopic Ultrasound
Youichirou Nushijima, Katsutoshi Nakano, Keishi Sugimoto, Kazunori Nakaguchi, Kazuomi Kan, Hirohide Maruyama, Sadayuki Doi, Shu Okamura, Kohei Murata
Metastatic gastric cancer is uncommon, and metastasis of colorectal cancer to the stomach is extremely rare. We report a case of metastatic gastric cancer that originated from transverse colon cancer. A 52-year-old woman underwent a left hemicolectomy and D3 lymph node dissection based on a diagnosis of transverse colon cancer. The pathology results were as follows: mucinous adenocarcinoma, type 2, 6 × 11 cm, ss, ly1 v1, pm (-), dm (-), n1 (+), P0, H0, M0, Stage IIIa. The patient received XELOX as postoperative adjuvant therapy for 6 months...
November 2014: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Yutaka Yagi, Toshiyuki Yamazaki, Akira Iwaya, Shoichi Manabe
A 40-year-old woman visited her primary care physician because she had pain in the upper right part of the abdomen. She was diagnosed with descending colon cancer with multiple liver metastases, and was referred to our department. After a laparoscopic abdominal colectomy for removal of the original lesion, chemotherapy was initiated with a modified combination of folinic acid, 5-fluorouracil, and oxaliplatin (mFOLFOX6) + panitumumab. After 12 courses of treatment with the mFOL FOX6 + panitumumab combination, followed by 13 courses of the simplified biweekly 5-fluorouracil and Leucovorin (sLV5FU2) + panitumumab combination, her liver tumors had regressed to about 90% of their original size...
January 2015: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Katarina Levic, Monica Kjær, Orhan Bulut, Per Jess, Thue Bisgaard
INTRODUCTION: Unexpected malignancy in removed colorectal polyps is reported in up to 9% of cases. The introduction of screening for colorectal cancer will inevitably increase the number of removed colorectal polyps and therefore also the incidence of malignant polyps. The treatment strategy is either watchful waiting or subsequent colorectal resection. The aim of this study was to perform a preliminary evaluation of the oncological results of polypectomy for malignant polyps with or without subsequent resection, including the patients' long-term survival...
January 2015: Danish Medical Journal
Miguel Calero-Garcia, H Bobby Gaspar
CRISPR/Cas9 has recently been introduced as a gene editing tool and shows considerable promise. In this issue of Cell Stem Cell, Mandal et al. (2014) show efficient CRISPR/Cas9-mediated ablation of the CCR5 and B2M genes in primary human hematopoietic cells, two editing strategies that are potentially translatable into clinical application.
November 6, 2014: Cell Stem Cell
Shuang Shi, Qi-Gen Fang, Changfu Sun
We reported 1 case of salivary duct carcinoma (SDC) in the mandible. The patient complained of pain and a growing mass in the right submandibular area for approximately 2 months. On clinical examination, there was a mass under the right angle of the mandible with a size of approximately 3 × 3 cm, a smooth surface, a poor activity, and a hard texture. Panoramic radiograph revealed poorly circumscribed area. Computed tomography presented mandible central destruction. Biopsy examination showed a malignant tumor that originated in the central epithelium of the mandible...
November 2014: Journal of Craniofacial Surgery
H Cao, X Kou, R Yang, D Liu, X Wang, Y Song, L Feng, D He, Y Gan, Y Zhou
The sympathetic nervous system (SNS) regulates bone resorption through β-2 adrenergic receptor (Adrb2). In orthodontic tooth movement (OTM), mechanical force induces and regulates alveolar bone remodeling. Compressive force-associated osteoclast differentiation and alveolar bone resorption are the rate-limiting steps of tooth movement. However, whether mechanical force can activate Adrb2 and thus contribute to OTM remains unknown. In this study, orthodontic nickel-titanium springs were applied to the upper first molars of rats and Adrb1/2(-/-) mice to confirm the role of SNS and Adrb2 in OTM...
November 2014: Journal of Dental Research
Wei Meng, Weiguo Zhou, Guangfei Li, Qingxiang Zhagn, Guolian Li, Hui Zhou, Shanchun Gong
OBJECTIVE: To discuss the clinical efficacy of adenoidectomy and tonsillectomy for the OSAHS children with sinusitis. METHOD: Reviewing 112 cases of children with OSAHS, in which the 80 patients without chronic sinusitis, 32 ones with chronic sinusitis. Among them, 103 cases of children with adenoidectomy, tonsil resection, 9 cases adenoidectomy only. We did questionnaire survey before and after surgeryand also did post-surgery clinical follow-up. RESULT: The effective rate was 90...
April 2014: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Weigang Gu, Per Jonasson
Basilar stroke is one of the most devastating acute cerebral vascular events. Intravascular thrombectomy may be performed beyond the 4.5 hours intravenous thrombolysis time window. However, the time window for thrombectomy in basilar stroke remains unclear. In our clinics, two cases of coma of unknown origin were diagnosed through CT angiography as distal basilar occlusion and treated with thromb-ectomy. Recanalization was achieved at 10 hours after stroke onset in case 1 and at 13 hours in case 2. The first patient regained consciousness shortly after operation and walked unlimited at 2 months after stroke...
2014: Läkartidningen
Mihir Kothari, Kavita Rao, Samita Moolani
Progressive anterior segment fibrosis syndrome (ASFS), after intraocular surgery in older children (≥ 9 years) and adults with congenital aniridia, is described in the literature. In this report, we describe an unique case of ASFS in an infant with congenital aniridia following a combined trabeculotomy-ectomy and its recurrence after a descemet stripping endothelial keratoplasty. The ophthalmologists should be well aware of this entity and warn the parents about its possibilities. Use of immunomodulators or prolonged anti-inflammatory therapy may be considered to prevent its occurrence...
February 2014: Indian Journal of Ophthalmology
Jun-sheng Peng, Shi Chen
Pancreaticoduodenectomy(PD) has been widely accepted as one of the most complicated operation in abdominal surgery. The patients who receive PD operation always have other concurrent conditions, such as jaundice, diabetes, liver dysfunction, and malnutrition. Pancreatic fistula, biliary fistula and gastrointestinal dysfunction are common complications after PD. Proper perioperative management and fluid administration can reduce postoperative complications and the mortality.
November 2013: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
Bjoern Sommer, Burkhard Sebastian Kasper, Roland Coras, Ingmar Blumcke, Hajo Martinus Hamer, Michael Buchfelder, Karl Roessler
Cure from seizures due to cavernomas might be surgically achieved dependent on both, the complete removal of the cavernoma as well as its surrounding hemosiderin rim. High field intraoperative MRI imaging (iopMRI) and neuronavigation might play a crucial role to achieve both goals. Were trospectively investigated the long-term results and impact of intraoperative 1.5T MRI (iopMRI) andneuronavigation on the completeness of surgical removal of a cavernous malformation (CM) and its perilesional hemosiderin rim as well as reduction of surgical morbidity...
August 22, 2013: Neurological Research
Markus Kreuzthaler, Stefan Schulz
Metonymies are language phenomena, in which one expression is used to refer to a related one. Whereas there are many examples in medical discourse, it has been controversially discussed to what extent metonymic phenomena also matter in medical terminologies like SNOMED CT, where they could hamper their proper use. We investigated this by analyzing all SNOMED CT single word fully specified names containing the suffixes "-itis" and "-ectomy". Using a combination of string and concept matching, we harvested definitional phrases from the Web and contrasted them with the terms and their logical definitions as stated in SNOMED CT...
2012: AMIA ... Annual Symposium Proceedings
Yan Lin, Zhe Cheng, Shi-long Zhan, Jian-qing Ye, Tong-hai Fan, Wei-dong Liu, Yin-hua Jiang
PURPOSE: To investigate the feasibility and indication of condylectomy for treatment of comminuted fractures of the condyle above the neck. METHODS: Sixty-one patients with condylar fractures, treated between September 2007 and September 2011 were reviewed respectively. Among them, 30 underwent open reduction and internal fixation, 15 underwent conservative therapy, and 16 patients (18 sides) who had comminuted fractures of the condyle above the neck underwent condylectomy...
October 2012: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
Qian Wang, Wenchao Wu, Xiaoying Chen, Chenqi He, Xiaojing Liu
Pulsed electromagnetic field (PEMF), a non-invasive physical treatment modality, is now used clinically to promote bone formation for osteoporosis. The patients after ectomy of ovarian cancer are easily complicated with osteoporosis. However, the safety parameters of PEMF treatment for the osteoporosis patients after resection of ovarian cancer remain unknown. Therefore, this study was designed to examine the effect of different frequency of PEMF on the proliferation, apoptosis and migration of human ovarian cancer cells (SKOV3 cells)...
April 2012: Sheng Wu Yi Xue Gong Cheng Xue za Zhi, Journal of Biomedical Engineering, Shengwu Yixue Gongchengxue Zazhi
Bo Kong, Wen-de Zhang
OBJECTIVE: To investigate the effect of incretion hormones on growth pituitary adenoma ectomy patients and evaluate its long-term therapeutic efficacy. METHODS: A total of 38 growth pituitary adenoma patients were treated by adenoma ectomy between 2002 to 2009 at our hospital. The dynamic concentrations of serum prolactin (PRL), growth hormone (GH), cortisone, adrenocorticotrophic hormone (ACTH) and thyroid function (T3, T4 & thyroid-stimulating hormone) were monitored before and after microsurgery...
August 23, 2011: Zhonghua Yi Xue za Zhi [Chinese medical journal]
N Sleeckx, H de Rooster, E J B Veldhuis Kroeze, C Van Ginneken, L Van Brantegem
Canine mammary tumours (CMTs) are the most common neoplasms in intact female dogs. Although the prevalence of these tumours decreases in regions where preventive ovari(ohyster)ectomy is performed, it remains an important disease entity in veterinary medicine. Moreover, treatment options are limited in comparison with human breast cancer. Nevertheless, recent human treatment protocols might have potential in bitches suffering from CMTs.
December 2011: Reproduction in Domestic Animals, Zuchthygiene
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