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central line associated bloodstream infection

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https://www.readbyqxmd.com/read/28807074/a-model-to-predict-central-line-associated-bloodstream-infection-among-patients-with-peripherally-inserted-central-catheters-the-mpc-score
#1
Erica Herc, Payal Patel, Laraine L Washer, Anna Conlon, Scott A Flanders, Vineet Chopra
BACKGROUND Peripherally inserted central catheters (PICCs) are associated with central-line-associated bloodstream infections (CLABSIs). However, no tools to predict risk of PICC-CLABSI have been developed. OBJECTIVE To operationalize or prioritize CLABSI risk factors when making decisions regarding the use of PICCs using a risk model to estimate an individual's risk of PICC-CLABSI prior to device placement. METHODS Using data from the Michigan Hospital Medicine Safety consortium, patients that experienced PICC-CLABSI between January 2013 and October 2016 were identified...
August 15, 2017: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/28782651/emergence-of-dalbavancin-non-susceptible-vancomycin-intermediate-staphylococcus-aureus-visa-after-treatment-of-mrsa-central-line-associated-bloodstream-infection-with-a-dalbavancin-and-vancomycin-containing-regimen
#2
Brian J Werth, Rupali Jain, Andrew Hahn, Lisa Cummings, Tatiana Weaver, Adam Waalkes, Dhruba Sengupta, Stephen J Salipante, Robert M Rakita, Susan M Butler-Wu
OBJECTIVES: Dalbavancin is a long-acting lipoglycopeptide with activity against Gram-positives, including methicillin-resistant Staphylococcus aureus(MRSA). The potential for lipoglycopeptides, with half-lives greater than one-week, to select for resistance is unknown. Here we explore a case of MRSA central line-associated blood stream infection in which dalbavancin and vancomycin non-susceptibility emerged in a urine isolate collected after the patient was treated with vancomycin and dalbavancin sequentially...
August 3, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28762227/-chlorhexidine-bed-bath-improves-clabsi-a-meta-analysis
#3
Shu-Cing Lin, Chair-Hua Lin, Chin-Ching Yu
BACKGROUND: Central catheters are used primarily in ICU settings. Bloodstream infections in the central line of central catheters have been shown to cause longer hospital stays for patients and result in higher medical costs. PURPOSE: The present study applies a systematic review and meta-analysis to assess the effect of a 2% chlorhexidine (CHG) bed-bath on the risk of central line-associated bloodstream infections (CLABSI). METHODS: The Public Health Resource Unit of England issued the Critical Appraisal Skills Programme and evaluated the standardized crucial appraisal tools from the Joanna Briggs Institute that are used to assess methodological quality...
August 2017: Hu Li za Zhi the Journal of Nursing
https://www.readbyqxmd.com/read/28750921/the-methodology-of-surveillance-for-antimicrobial-resistance-and-healthcare-associated-infections-in-europe-suspire-a-systematic-review-of-publicly-available-information
#4
REVIEW
María Núñez-Núñez, María Dolores Navarro, Virginia Palomo, Nithya Babu Rajendran, María Dolores Del Toro, Andreas Voss, Mike Sharland, Frangiscos Sifakis, Evelina Tacconelli, Jesús Rodríguez-Baño
OBJECTIVES: Surveillance is a key component of any control strategy for health-care associated infections (HAIs) and antimicrobial resistance (AMR), and public availability of methodological aspects is crucial for the interpretation of the data. We sought to systematically review publicly available information for HAIs and/or AMR surveillance systems organised by public institutions or scientific societies in European countries. METHODS: A systematic review of scientific and grey literature following the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines was performed...
July 24, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28745951/preventing-bloodstream-infection-in-iv-therapy
#5
Kevin Hugill
Healthcare-associated infections (HAI) are one cause of preventable harm to patients, and are a clinical, political and economic concern. Vascular access, via a peripheral or central vascular device, is a routine experience for most patients receiving hospital care and is increasingly commonplace in health care at home. Because it is so common, ensuring safe vascular access is an essential focus for all health professionals. All vascular access procedures are invasive, regardless of patient group, therapeutic rationale, the device used, route and site of insertion and particular technique...
July 27, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28743336/-analysis-of-factors-affecting-the-prognosis-of-icu-patients-by-multiple-logistic-regression-model-a-retrospective-cohort-study-of-1-299-patients-in-12-consecutive-years
#6
Jianfeng Liang, Zhiyong Li, Yan Zhang, Wei Zhang, Haishan Dong, Yun Zhang, Chang Xu, Maolong Gao
OBJECTIVE: To explore the prognostic factors of intensive care unit (ICU) patients. METHODS: A retrospective cohort study was conducted. The clinical data of patients admitted to ICU of Beijing Geriatric Hospital from January 2005 to December 2016 were collected. According to the prognosis, the patients were divided into death group and survival group, and the mortality trend with time and age was observed. Survival and death were treated as dependent variables, while the gender, age, reason of ICU admission, acute physiology and chronic health evaluation II (APACHE II) score, whether undergoing invasive mechanical ventilation (MV), invasive MV reason, duration of invasive MV, whether successful weaning, whether ICU nosocomial infection, hospital acquired pneumonia (HAP), central line-associated bloodstream infection (CLABSI), acute kidney injury (AKI) occurred, whether undergoing continuous blood purification (CBP), whether septic shock occurred, whether undergoing invasive hemodynamic monitoring or blood transfusion and length of ICU stay were used as the independent variables...
July 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28736032/central-line-associated-bloodstream-infection-rate-elevation-attributable-to-national-healthcare-safety-network-surveillance-definition-changes-ongoing-opportunities-for-infection-prevention-or-both
#7
Andrew Corley, Maggie Cantara, Julia Gardner, Polly Trexler, Clare Rock, Lisa L Maragakis
Calendar year 2015 intensive care unit (ICU) central line-associated bloodstream infections (CLABSIs) from 1 hospital were reviewed using 2014 CLABSI surveillance definitions to assess the relative impact of definition changes and infection control practices on CLABSI rates. Increased ICU primary CLABSI rates were found to be a result of both surveillance definition changes and infection control practices.
July 20, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28736021/infectious-complications-and-multidrug-resistant-bacteria-in-patients-with-hematopoietic-stem-cell-transplantation-in-the-first-12-months-after-transplant
#8
A César-Arce, P Volkow-Fernández, L M Valero-Saldaña, B Acosta-Maldonado, D Vilar-Compte, P Cornejo-Juárez
BACKGROUND: Hematopoietic stem cell transplantation (HSCT) has been used as treatment in different hematologic and solid malignancies. The aim of this study was to describe the frequency of infectious complications, microbiology, and outcome in patients undergoing HSCT in Mexico during the pre-engraftment period and the impact on mortality rates at 12 months. METHODS: We conducted a retrospective study of all hematologic malignancies that received HSCT from January 2009 and December 2014, at an oncology reference center...
July 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28707497/complications-of-central-lines-in-neonates-admitted-to-a-level-iii-neonatal-intensive-care-unit
#9
Beatriz Nicolau Soares, Susana Pissarra, Ana Lídia Rouxinol-Dias, Sandra Costa, Hercília Guimarães
OBJECTIVE: To investigate the incidence and risk factors for central line related complications in neonates. METHODS: A retrospective cohort study of infants who underwent central line (CL) placement, from 1 July 2014 to 31 June 2016, was conducted in Neonatal Intensive Care Unit of Centro Hospitalar de São João. Infants hospitalized more than 2 d and CLs placed for more than 24 h were included. Patients' demographic characteristics, hospital data, and information on CLs were collected...
July 25, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28689878/systematic-review-of-antimicrobial-lock-therapy-for-prevention-of-central-line-associated-bloodstream-infections-in-adult-and-pediatric-cancer-patients
#10
REVIEW
LeAnn B Norris, Farah Kablaoui, Maggie K Brilhart, P Brandon Bookstaver
BACKGROUND: Central venous catheter (CVC) use is commonplace in cancer patients. Antimicrobial lock therapy (ALT), the instillation of a concentrated antimicrobial solution into the catheter lumen, is one method for preventing infection among CVCs. This systematic review discusses the effectiveness and safety of prophylactic ALT in cancer patients with CVCs. METHODS: A literature search was performed using the Medline database and Google Scholar from inception until April 2016...
July 6, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28687213/prevention-of-central-line-associated-bloodstream-infections
#11
REVIEW
Taison Bell, Naomi P O'Grady
Central venous catheters (CVCs) are commonly used in critically ill patients and offer several advantages to peripheral intravenous access. However, indwelling CVCs have the potential to lead to bloodstream infections, with the risk increasing with an array of characteristics, such as catheter choice, catheter location, insertion technique, and catheter maintenance. Evidence-based guidelines have led to a significant reduction in the incidence of bloodstream infections associated with CVCs. The combination of guideline implementation and newer technologies has the potential to further reduce morbidity and mortality from infections related to CVCs...
September 2017: Infectious Disease Clinics of North America
https://www.readbyqxmd.com/read/28684127/improving-central-line-maintenance-to-reduce-central-line-associated-bloodstream-infections
#12
Frank A Drews, Jonathan Z Bakdash, Jeremy R Gleed
OBJECTIVE: A human factors engineering-based intervention aimed at the modification of task behavior to increase adherence to best practices and the reduction of central line-associated bloodstream infections (CLABSI). The hypothesis was tested that a central line maintenance kit would improve adherence and reduce CLABSI compared with a standard, nonkit-based method of performing central line maintenance. DESIGN: The study design was a 29-month prospective, interventional, nonrandomized, observational, and clinical research study using a pre-post implementation assessment...
July 3, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28676849/bloodstream-infection-incidence-of-different-central-venous-catheters-in-neonates-a-descriptive-cohort-study
#13
Gerdina H Dubbink-Verheij, Vincent Bekker, Iris C M Pelsma, Erik W van Zwet, Vivianne E H J Smits-Wintjens, Sylke J Steggerda, Arjan B Te Pas, Enrico Lopriore
Central venous catheters (CVCs) in neonates are associated with a risk of central line-associated bloodstream infections (CLABSI). Most reports on the incidence of CLABSI in neonates focus on umbilical venous catheters (UVCs) and peripherally inserted central catheters (PICCs). We evaluated the incidence and risk factors for CLABSI in a cohort of neonates with femoral venous catheters (FVCs), UVCs, and PICCs, with a gestational age ≥34 weeks born between January 1, 2006 and June 30, 2013. We included 2,986 neonates with a total of 656 catheters...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28669363/the-effect-of-adding-comorbidities-to-current-centers-for-disease-control-and-prevention-central-line-associated-bloodstream-infection-risk-adjustment-methodology
#14
Sarah S Jackson, Surbhi Leekha, Laurence S Magder, Lisa Pineles, Deverick J Anderson, William E Trick, Keith F Woeltje, Keith S Kaye, Kristen Stafford, Kerri Thom, Timothy J Lowe, Anthony D Harris
BACKGROUND Risk adjustment is needed to fairly compare central-line-associated bloodstream infection (CLABSI) rates between hospitals. Until 2017, the Centers for Disease Control and Prevention (CDC) methodology adjusted CLABSI rates only by type of intensive care unit (ICU). The 2017 CDC models also adjust for hospital size and medical school affiliation. We hypothesized that risk adjustment would be improved by including patient demographics and comorbidities from electronically available hospital discharge codes...
July 3, 2017: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/28665993/knowledge-attitudes-and-practice-on-the-prevention-of-central-line-associated-bloodstream-infections-among-nurses-in-oncological-care-a-cross-sectional-study-in-an-area-of-southern-italy
#15
Maria Rosaria Esposito, Assunta Guillari, Italo Francesco Angelillo
The objectives of the cross-sectional study were to delineate the knowledge, attitudes, and behavior among nurses regarding the prevention of central line-associated bloodstream infections (CLABSIs) and to identify their predisposing factors. A questionnaire was self-administered from September to November 2011 to nurses in oncology and outpatient chemotherapy units in 16 teaching and non-teaching public and private hospitals in the Campania region (Italy). The questionnaire gathered information on demographic and occupational characteristics; knowledge about evidence-based practices for the prevention of CLABSIs; attitudes towards guidelines, the risk of transmitting infections, and hand-washing when using central venous catheter (CVC); practices about catheter site care; and sources of information...
2017: PloS One
https://www.readbyqxmd.com/read/28663107/prevention-of-central-venous-line-associated-bloodstream-infections-in-adult-intensive-care-units-a-systematic-review
#16
Diana Carolina Velasquez Reyes, Melissa Bloomer, Julia Morphet
BACKGROUND: In adult Intensive Care Units, the complexity of patient treatment requirements make the use of central venous lines essential. Despite the potential benefits central venous lines can have for patients, there is a high risk of bloodstream infection associated with these catheters. AIM: Identify and critique the best available evidence regarding interventions to prevent central venous line associated bloodstream infections in adult intensive care unit patients other than anti-microbial catheters...
June 26, 2017: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
https://www.readbyqxmd.com/read/28659159/searching-for-management-approaches-to-reduce-hai-transmission-smart-a-study-protocol
#17
Ann Scheck McAlearney, Jennifer L Hefner, Cynthia J Sieck, Daniel M Walker, Alison M Aldrich, Lindsey N Sova, Alice A Gaughan, Caitlin M Slevin, Courtney Hebert, Erinn Hade, Jacalyn Buck, Michele Grove, Timothy R Huerta
BACKGROUND: Healthcare-associated infections (HAIs) impact patients' lives through prolonged hospitalization, morbidity, and death, resulting in significant costs to both health systems and society. Central line-associated bloodstream infections (CLABSIs) and catheter-associated urinary tract infections (CAUTIs) are two of the most preventable HAIs. As a result, these HAIs have been the focus of significant efforts to identify evidence-based clinical strategies to reduce infection rates...
June 28, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28651859/dwell-time-and-risk-of-central-line-associated-bloodstream-infection-in-neonates
#18
Erica Sanderson, Kee Thai Yeo, Alex Yueping Wang, Ian Callander, Barbara Bajuk, Srinivas Bolisetty, Kei Lui
BACKGROUND: Umbilical venous catheters (UVC) or peripherally inserted central catheters (PICC), commonly used in high risk neonates, may have a threshold dwell time for subsequent increased risk of central line associated blood stream infection (CLABSI). AIM: To evaluate the CLABSI risks in neonates having either UVC, PICC or those having both sequentially. METHODS: Study included 3985 infants who had UVC or PICC inserted between 2007 and 2009 cared for in 10 regional Neonatal Intensive Care Units: 1392 having UVC only (Group 1), 1317 PICC only (Group 2) and 1276 both UVC and PICC (Group 3)...
June 23, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28634973/the-role-of-a-surveillance-programme-for-intro-ducing-peripherally-inserted-central-catheters-a-2-year-observational-study-in-an-academic-hospital
#19
Elia Lo Priore, Monika Fliedner, Johannes T Heverhagen, Urban Novak, Jonas Marschall
AIMS OF THE STUDY: In our hospital, a previous attempt to introduce peripherally inserted central catheters (PICC) was aborted after a nonsystematic approach, seemingly accompanied by high rates of complications. The goal of this new interdisciplinary project was to introduce PICCs in an academic hospital, with an embedded interdisciplinary surveillance programme for both infectious and noninfectious outcomes. METHODS: We prospectively collected data for this surveillance study from all patients who underwent PICC insertion from 1 January 2014 and had the catheter removed by 31 December 2015 in our 950-bed academic hospital (Bern University Hospital, Switzerland)...
June 21, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/28633680/impact-of-organism-identification-method-on-central-line-associated-bloodstream-infection-designation
#20
Emily J Gomez, Amity L Roberts, Diana P Robinson, Kevin Alby, Nathan A Ledeboer, Christopher D Doern, David W Lander, Gonzalo Bearman, Kaede V Sullivan
No abstract text is available yet for this article.
June 21, 2017: Infection Control and Hospital Epidemiology
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