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https://www.readbyqxmd.com/read/28524126/-impact-of-sagittal-balance-parameters-on-life-quality-in-elderly-and-senile-patients-after-surgery-for-degenerative-lumbar-spine-stenosis
#1
V S Klimov, I I Vasilenko, A V Evsyukov, E V Amelina
INTRODUCTION: As the life span and proportion of people over 65 years increase, the incidence of degenerative lumbar spine stenosis grows proportionally. Various parameters of the spinopelvic relationships are used to predict surgical treatment outcomes in patients with degenerative spine diseases. There are no unified protocols for evaluation, in terms of the sagittal balance, of surgical treatment outcomes in elderly patients. PURPOSE: To study the impact of sagittal balance parameters on the life quality of elderly and senile patients after surgery for degenerative stenosis of the lumbar spine...
2017: Zhurnal Voprosy Neĭrokhirurgii Imeni N. N. Burdenko
https://www.readbyqxmd.com/read/28522402/prophylactic-vertebral-cement-augmentation-at-the-uppermost-instrumented-vertebra-and-rostral-adjacent-vertebra-for-the-prevention-of-proximal-junctional-kyphosis-and-failure-following-long-segment-fusion-for-adult-spinal-deformity
#2
George M Ghobrial, Daniel G Eichberg, John Paul G Kolcun, Karthik Madhavan, Nathan H Lebwohl, Barth A Green, Joseph P Gjolaj
BACKGROUND CONTEXT: Proximal junctional kyphosis (PJK) and proximal junctional failure (PJF) are common problems after long segment (>5 levels) thoracolumbar instrumented fusions in the treatment of adult spinal deformity (ASD). No specific surgical strategy has definitively been shown to lower the risk of PJK as the result of a multifactorial etiology. PURPOSE: To assess the incidence of PJK and PJF in patients treated with prophylactic polymethylmethacrylate(PMMA) cement augmentation at the uppermost instrumented vertebrae(UIV) and rostral adjacent vertebrae(UIV+1)...
May 15, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28520681/delayed-dural-leak-following-posterior-spinal-fusion-for-idiopathic-scoliosis-using-all-posterior-pedicle-screw-technique
#3
Lorena V Floccari, A Noelle Larson, Anthony A Stans, Jeremy Fogelson, Iikka Helenius
BACKGROUND: In pediatric patients, pedicle screws are malpositioned 5% to 15% of the time. Complications associated with malpositioned screws are infrequently reported in the literature. We present a series of adolescent idiopathic scoliosis (AIS) patients who presented in a delayed manner with positional headache and chronic dural leak adjacent to the pedicle screw tract. METHODS: Scoliosis databases at 2 centers were reviewed, and cases of delayed positional headaches following posterior spinal fusion for AIS were identified...
May 17, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28516752/growth-hormone-treatment-and-adverse-events
#4
Yoshikazu Nishi, Toshiaki Tanaka
We compiled the major adverse events included in the Annual Research Reports of the Foundation for Growth Research published in and after 2000. We conducted a review of approximately 32,000 patients treated with growth hormone (GH) who subsequently developed leukemia and who were registered with the Foundation for Growth Research (from 1975 to December 31 1997). We performed a literature review and found that GH therapy was not associated with leukemia onset in patients with no risk factors for leukemia. We also reported the onset of diabetes mellitus (DM), scoliosis, and respiratory problems in patients with Prader-Willi syndrome who were treated with GH...
March 2017: Pediatric Endocrinology Reviews: PER
https://www.readbyqxmd.com/read/28516166/onset-and-remodeling-of-coronal-imbalance-after-selective-posterior-thoracic-fusion-for-lenke-1c-and-2c-adolescent-idiopathic-scoliosis-a-pilot-study
#5
Masayuki Ishikawa, Kai Cao, Long Pang, Nobuyuki Fujita, Mitsuru Yagi, Naobumi Hosogane, Takashi Tsuji, Masafumi Machida, Shinichi Ishihara, Makoto Nishiyama, Yasuyuki Fukui, Masaya Nakamura, Morio Matsumoto, Kota Watanabe
BACKGROUND: Postoperative coronal imbalance is a significant problem after selective thoracic fusion for primary thoracic and compensatory lumbar curves in adolescent idiopathic scoliosis (AIS). However, longitudinal studies on postoperative behavior of coronal balance are lacking. This multicenter retrospective study was conducted to analyze factors related to onset and remodeling of postoperative coronal imbalance after posterior thoracic fusion for Lenke 1C and 2C AIS. METHODS: Twenty-one Lenke 1C or 2C AIS patients, who underwent posterior thoracic fusion ending at L3 or above, were included with a minimum 2-year follow-up...
2017: Scoliosis and Spinal Disorders
https://www.readbyqxmd.com/read/28509688/a-prevalence-study-of-thoracic-scoliosis-in-chilean-patients-aged-10-20-years-using-chest-radiographs-as-a-screening-tool
#6
Julio Urrutia, Pablo Besa, Francisco Bengoa
To determine the prevalence of thoracic scoliosis in patients 10-20 years old using radiographs as a screening tool, we studied 783 patients who obtained chest radiographs for nonspinal reasons. We measured thoracic curvature in coronal and sagittal planes; we determined whether age, sex, and sagittal curvature predicted the coronal curvature. The prevalence of scoliosis was 9.3%: 7.0% had curvatures 10°-20°; 1.0% had curvatures 20°-30°; and 1.3% had curvatures of at least 30°. Females (13%) presented larger prevalence of scoliosis than males (4...
May 15, 2017: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/28508821/measuring-the-negative-impact-of-long-sitting-hours-at-high-school-students-using-the-microsoft-kinect
#7
Norbert Gal-Nadasan, Emanuela Georgiana Gal-Nadasan, Vasile Stoicu-Tivadar, Dan V Poenaru, Diana Popa-Andrei
This paper suggests the usage of the Microsoft Kinect to detect the onset of the scoliosis at high school students due to incorrect sitting positions. The measurement is done by measuring the overall posture in orthostatic position using the Microsoft Kinect. During the measuring process several key points of the human body are tracked like the hips and shoulders to form the postural data. The test was done on 30 high school students who spend 6 to 7 hours per day in the school benches. The postural data is statistically processed by IBM Watson's Analytics...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28508768/inveterate-42-year-old-hip-dislocation-treated-with-arthroplasty-a-case-study
#8
Tomasz Pitera, Grzegorz Guzik, Piotr Biega
Dislocation of the hip usually results from a high-energy injury sustained during a road accident. Inveterate dislocations persisting for many months or years are extremely rare. Selection of an appropriate treatment method is not easy and is always associated with the risk of serious complications. The present authors hope that a description of the course of diagnostic work-up and treatment of a patient in whom a hip dislocation persisted for 42 years will prove interesting and helpful for orthopaedists who may encounter such a case in their practice...
April 12, 2017: Ortopedia, Traumatologia, Rehabilitacja
https://www.readbyqxmd.com/read/28508607/sequelae-of-gh-treatment-in-children-with-pws
#9
Maïthé Tauber, Gwenaelle Diene, Catherine Molinas
More than 15 years after rGH was granted marketing authorization for children with PWS, a review of the sequelae, side effects and safety issues of rGH therapy is timely. The publications on issues concerning respiratory function, glucose metabolism, fat mass, and scoliosis at baseline and with rGH treatment are herein presented. We discuss the impact of rGH side effects, make proposals to prevent or treat them, and emphasise the remaining questions and perspectives. As a whole, the benefit /risk ratio is positive, although questions are raised about the role of GH in premature pubarche and its long-term effects, particularly the potential long-term oncogenic risk...
December 2016: Pediatric Endocrinology Reviews: PER
https://www.readbyqxmd.com/read/28506822/the-effect-of-prophylactic-vertebroplasty-on-the-incidence-of-proximal-junctional-kyphosis-and-proximal-junctional-failure-following-posterior-spinal-fusion-in-adult-spinal-deformity-a-5-year-follow-up-study
#10
Tina Raman, Emily Miller, Christopher T Martin, Khaled Kebaish
BACKGROUND CONTEXT: The incidence of proximal junctional kyphosis (PJK) ranges from 5-46% following adult spinal deformity (ASD) surgery. Approximately 66-76% of PJK occurs within 3 months of surgery. A subset of these patients, reportedly 26-47%, develop proximal junctional failure (PJF) within 6 months postoperatively. To date, there are no studies evaluating the impact of prophylactic vertebroplasty on PJK/PJF incidence at long term follow-up. PURPOSE: The purpose of this study is to evaluate the long term radiographic and clinical outcomes, and incidence of PJK and PJF, after prophylactic vertebroplasty for long segment thoracolumbar posterior spinal fusion...
May 12, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28506755/-analysis-of-the-quality-of-life-in-patients-affected-by-scoliosis
#11
M Leal-Hernández, F Martínez-Monje, M Pérez-Valencia, R García-Romero, R Mena-Poveda, J Caballero-Cánovas
OBJECTIVES: To assess the quality of life using the SRS 22 test in patients with scoliosis of 20 or more degrees Cobb. MATERIAL AND METHODS: A prospective descriptive study was conducted between April and May 2016 on patients with scoliosis of at least 20 degrees Cobb and aged between 10 and 20 years. A record was made of weight, height, body mass index, and the SR 22 specific quality of life questionnaire for patients with scoliosis was completed. Patients were divided into two groups for analysis: a) scoliosis between 20 and 29 degrees Cobb (n=44); and b) scoliosis with a Cobb of 30 degrees or greater (n=32)...
May 11, 2017: Semergen
https://www.readbyqxmd.com/read/28506345/-infantile-hypophosphatasia-caused-by-a-novel-compound-heterozygous-mutation-a-case-report-and-pedigree-analysis
#12
Deng-Feng Li, Dan Lan, Jing-Zi Zhong, Roma Kajal Dewan, Yan-Shu Xie, Ying Yang
This article reported the clinical features of one child with infantile hypophosphatasia (HPP) and his pedigree information. The proband was a 5-month-old boy with multiple skeletal dysplasia (koilosternia, bending deformity of both radii, and knock-knee deformity of both knees), feeding difficulty, reduction in body weight, developmental delay, recurrent pneumonia and respiratory failure, and a significant reduction in blood alkaline phosphatase. Among his parents, sister, uncle, and aunt (other family members did not cooperate with us in the examination), his parents and aunt had a slight reduction in alkaline phosphatase and his aunt had scoliosis; there were no other clinical phenotypes or abnormal laboratory testing results...
May 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/28503541/effects-of-12-week-core-stabilization-exercise-on-the-cobb-angle-and-lumbar-muscle-strength-of-adolescents-with-idiopathic-scoliosis
#13
Kwang-Jun Ko, Seol-Jung Kang
To identify the effects of core stabilization exercise on the Cobb angle and lumbar muscle strength of adolescent patients with idiopathic scoliosis. Subjects in the present study consisted of primary school students who were confirmed to have scoliosis on radiologic examination performed during their visit to the National Fitness Center in Seoul, Korea. Depending on whether they participated in a 12-week core stabilization exercise program, subjects were divided into the exercise (n=14, age 12.71±0.72 years) or control (n=15, age 12...
April 2017: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/28503540/comparisons-of-incidence-of-spinal-and-lower-extremity-deformities-according-to-the-physical-characteristics-between-sports-major-and-nonmajor-college-students
#14
Jangwon Lee
This research was performed to identify the incidence of spinal and lower extremity deformity and to identify the relationship of the incidence between the physical characteristics. One hundred forty-seven Physical Education major students and 54 nonmajor students participated in this study. Data collecting was performed by questionnaire and visual postural evaluation. The incidences of genu varus (P<0.00001), genu recurvatum (P=0.0007), forward head (P<0.00001), lordosis (P<0.00001), and scoliosis (P=0...
April 2017: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/28502730/overgrowth-syndromes-caused-by-somatic-variants-in-the-phosphatidylinositol-3-kinase-akt-mammalian-target-of-rapamycin-pathway
#15
REVIEW
Gozde Akgumus, Fengqi Chang, Marilyn M Li
Somatic variants have been well described in tumorigenesis; however, they are only recently appreciated in other human disorders, such as mosaic overgrowth syndromes. Although overgrowth is a manifestation in many genetic syndromes, not all overgrowth syndromes are inherited. Mosaic somatic variants have been lately described in several overgrowth disorders, such as Proteus syndrome, CLOVES (congenital, lipomatous, overgrowth, vascular malformations, epidermal nevi, and spinal/skeletal anomalies and/or scoliosis) syndrome, megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome, and megalencephaly-capillary malformation-polymicrogyria syndrome...
May 11, 2017: Journal of Molecular Diagnostics: JMD
https://www.readbyqxmd.com/read/28500653/blood-transfusion-in-the-surgical-treatment-of-adolescent-idiopathic-scoliosis-a-single-center-experience-of-patient-blood-management-in-210-cases
#16
Søren Ohrt-Nissen, Naeem Bukhari, Casper Dragsted, Martin Gehrchen, Pär I Johansson, Jesper Dirks, Jakob Stensballe, Benny Dahl
BACKGROUND: The surgical treatment of adolescent idiopathic scoliosis can be associated with substantial blood loss, requiring allogeneic red blood cell (RBC) transfusion. This study describes the use of RBC and the effect of a standardized perioperative patient blood management program. STUDY DESIGN AND METHODS: Patients treated with posterior instrumented fusion were consecutively enrolled over a 6-year period. Patient blood management strategies were implemented in 2011, including prophylactic tranexamic acid, intraoperative permissive hypotension, restrictive fluid therapy (including avoidance of synthetic colloids), restrictive RBC trigger according to institutional standardized protocol, the use of cell savage, and goal-directed therapy according to thrombelastography...
May 12, 2017: Transfusion
https://www.readbyqxmd.com/read/28498505/autosomal-dominant-frontometaphyseal-dysplasia-delineation-of-the-clinical-phenotype
#17
Emma M Wade, Zandra A Jenkins, Philip B Daniel, Tim Morgan, Marie C Addor, Lesley C Adés, Debora Bertola, Axel Bohring, Erin Carter, Tae-Joon Cho, Christa M de Geus, Hans-Christoph Duba, Elaine Fletcher, Kinga Hadzsiev, Raoul C M Hennekam, Chong A Kim, Deborah Krakow, Eva Morava, Teresa Neuhann, David Sillence, Andrea Superti-Furga, Hermine E Veenstra-Knol, Dagmar Wieczorek, Louise C Wilson, David M Markie, Stephen P Robertson
Frontometaphyseal dysplasia (FMD) is caused by gain-of-function mutations in the X-linked gene FLNA in approximately 50% of patients. Recently we characterized an autosomal dominant form of FMD (AD-FMD) caused by mutations in MAP3K7, which accounts for the condition in the majority of patients who lack a FLNA mutation. We previously also described a patient with a de novo variant in TAB2, which we hypothesized was causative of another form of AD-FMD. In this study, a cohort of 20 individuals with AD-FMD is clinically evaluated...
May 12, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28498293/what-is-the-actual-3d-representation-of-the-rib-vertebra-angle-difference-mehta-s-angle
#18
Rob C Brink, Tom P C Schlösser, Marijn van Stralen, Koen L Vincken, Moyo C Kruyt, Winnie C W Chu, Jack C Y Cheng, René M Castelein
STUDY DESIGN: Cross-sectional study. OBJECTIVE: To establish the relevance of the conventional two-dimensional (2D) RVAD and the relationship with the complex three-dimensional (3D) apical morphology in scoliosis. SUMMARY OF BACKGROUND DATA: The rib vertebra angle difference (RVAD, also known as Mehta's angle) describes apical rib asymmetry on conventional radiographs and was introduced as a prognostic factor for curve severity in early onset scoliosis, and later applied to other types of scoliosis as well...
May 11, 2017: Spine
https://www.readbyqxmd.com/read/28497045/high-rate-of-deformed-larvae-among-gynogenetic-brown-trout-salmo-trutta-m-fario-doubled-haploids
#19
Krzysztof Jagiełło, Tomasz Zalewski, Stefan Dobosz, Oliwia Michalik, Konrad Ocalewicz
Mitotic gynogenesis results in the production of fully homozygous individuals in a single generation. Since inbred fish were found to exhibit an increased frequency of body deformations that may affect their survival, the main focus of this research was to evaluate the ratio of individuals with spinal deformities among gynogenetic doubled haploids (DHs) brown trout as compared to nonmanipulated heterozygous individuals. Gynogenetic development was induced by the activation of brown trout eggs by UV-irradiated homologous and heterologous (rainbow trout) spermatozoa...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28495242/the-association-between-the-hospital-consumer-assessment-of-healthcare-providers-and-systems-hcahps-survey-and-real-world-clinical-outcomes-in-lumbar-spine-surgery
#20
Jay M Levin, Robert D Winkelman, Gabriel A Smith, Joseph Tanenbaum, Edward C Benzel, Thomas E Mroz, Michael P Steinmetz
BACKGROUND CONTEXT: The patient experience of care as measured by the Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) survey is currently used to determine hospital reimbursement. The current literature inconsistently demonstrates an association between patient satisfaction and surgical outcomes. PURPOSE: To determine whether patient satisfaction with hospital experience is associated with better clinical outcomes in lumbar spine surgery...
May 8, 2017: Spine Journal: Official Journal of the North American Spine Society
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