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https://www.readbyqxmd.com/read/28428016/the-role-of-low-level-laser-therapy-on-neuropathic-pain-relief-and-interleukin-6-expression-following-spinal-cord-injury-an-experimental-study
#1
Negin Mojarad, Atousa Janzadeh, Mahmoud Yousefifard, Farinaz Nasirinezhad
INTRODUCTION: The effect of Low Level Laser Therapy (LLLT) as a non-invasive treatment of spinal cord injury (SCI) is still under investigation. Therefore, the present study aimed to evaluate the effectiveness of LLLT on neuropathic pain and interleukin-6 (IL-6) expression following SCI in male rats. METHODS: 46 adult male rats were divided into 5 groups of control, SCI, treatment with methylprednisolone sodium succinate (MPSS), 1-week LLLT and 2-week LLLT. Animals underwent behavioral evaluations for motor behavior, level of allodynia and hyperalgesia every week...
April 17, 2017: Journal of Chemical Neuroanatomy
https://www.readbyqxmd.com/read/28422520/low-level-laser-therapy-improves-performance-and-reduces-fatigue-in-competitive-cyclists
#2
Fábio J Lanferdini, Rodrigo R Bini, Bruno M Baroni, Kelli D Klein, Felipe P Carpes, Marco A Vaz
Evidence supports that low-level laser therapy (LLLT) minimizes fatigue effects on muscle performance. However, the ideal LLLT dosage to improve athletes' performance during sports activities, such as cycling, is still unclear. Therefore, the goal of this study was to investigate the effects of different LLLT dosages on cyclists' performance in time-to-exhaustion tests. In addition, we looked at the effects of LLLT on the frequency content of the EMG signals to assess fatigue mechanisms. Twenty male competitive cyclists participated in a crossover, randomized, double-blind and placebo-controlled trial...
April 19, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28394081/the-effect-of-low-level-laser-therapy-as-an-adjunct-to-non-surgical-periodontal-treatment-on-gingival-crevicular-fluid-levels-of-transforming-growth-factor-beta-1-tissue-plasminogen-activator-and-plasminogen-activator-inhibitor-1-in-smoking-and-non-smoking
#3
F Pamuk, M Lütfioğlu, A Aydoğdu, C Z Koyuncuoglu, E Cifcibasi, O S Badur
BACKGROUND AND OBJECTIVE: This study aimed to investigate the effects of low-level laser therapy (LLLT) as an adjunct to scaling and root planing (SRP) on smoking and non-smoking patients with chronic periodontitis. MATERIAL AND METHODS: The study was conducted using a split-mouth design with 30 patients with chronic periodontitis (15 smokers, 15 non-smokers) and 30 healthy individuals matched for age, sex and smoking status as controls. Groups were constituted as follows: Cp+SRP+Sham: non-smokers with chronic periodontitis treated with SRP; Cp+SRP+LLLT: non-smokers with chronic periodontitis treated with SRP+LLLT; SCp+SRP+Sham: smokers with chronic periodontitis treated with SRP; SCp+SRP+LLLT: smokers with chronic periodontitis treated with SRP+LLLT; C: control group comprised of periodontally healthy non-smokers; SC: control group comprised of periodontally healthy smokers...
April 10, 2017: Journal of Periodontal Research
https://www.readbyqxmd.com/read/28392641/low-level-light-therapy-with-410-nm-light-emitting-diode-suppresses-collagen-synthesis-in-human-keloid-fibroblasts-an-in-vitro-study
#4
Hyun Soo Lee, Soo-Eun Jung, Sue Kyung Kim, You-Sun Kim, Seonghyang Sohn, You Chan Kim
BACKGROUND: Keloids are characterized by excessive collagen deposition in the dermis, in which transforming growth factor β (TGF-β)/Smad signaling plays an important role. Low-level light therapy (LLLT) is reported as effective in preventing keloids in clinical reports, recently. To date, studies investigating the effect of LLLT on keloid fibroblasts are extremely rare. OBJECTIVE: We investigated the effect of LLLT with blue (410 nm), red (630 nm), and infrared (830 nm) light on the collagen synthesis in keloid fibroblasts...
April 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28391087/effects-of-two-wattages-of-low-level-laser-therapy-on-orthodontic-tooth-movement
#5
M Milligan, Y Arudchelvan, S-G Gong
INTRODUCTION: Mixed outcomes have been found in animal and clinical studies with regard to the use of low-level laser therapy (LLLT) as a modality to accelerate orthodontic tooth movement (OTM). One major reason for the variable findings is the different methodologies and protocols for laser therapy use. OBJECTIVE: The aim of this study was to determine whether orthodontically moved molars exposed to two different wattages at the same energy density of LLLT exhibited differences in the amount of tooth movement and molecular and histological changes in the adjacent periodontal areas...
March 24, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28382433/apoptosis-induced-by-low-level-laser-in-polymorphonuclear-cells-of-acute-joint-inflammation-comparative-analysis-of-two-energy-densities
#6
Lúcia Mara Januário Dos Anjos, Adenilson de Souza da Fonseca, Jacy Gameiro, Flávia de Paoli
Anti-inflammatory property of low-level laser therapy (LLLT) has been widely described in literature, although action mechanisms are not always clarified. Thus, this study aimed to evaluate apoptosis mechanisms in the LLLT anti-inflammatory effects on the arthritis experimental model in vivo at two different energy densities (3 and 30 Jcm(-2)). Arthritis was induced in mice by zymosan solution, animals were distributed into five groups, and morphological analysis, immunocytochemistry and gene expressions for apoptotic proteins were performed...
April 5, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28377600/low-level-laser-facilitates-alternatively-activated-macrophage-microglia-polarization-and-promotes-functional-recovery-after-crush-spinal-cord-injury-in-rats
#7
Ji Wei Song, Kun Li, Zhuo Wen Liang, Chen Dai, Xue Feng Shen, Yu Ze Gong, Shuang Wang, Xue Yu Hu, Zhe Wang
Macrophages and resident microglia play an import role in the secondary neuroinflammation response following spinal cord injury. Reprogramming of macrophage/microglia polarization is an import strategy for spinal cord injury restoration. Low-level laser therapy (LLLT) is a noninvasive treatment that has been widely used in neurotrauma and neurodegenerative diseases. However, the influence of low-level laser on polarization of macrophage/microglia following spinal cord injury remains unknown. The present study applied low-level laser therapy on a crush spinal cord injury rat model...
April 4, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28349897/3d-printing-scaffold-coupled-with-low-level-light-therapy-for-neural-tissue-regeneration
#8
Wei Zhu, Jonathan K George, Volker J Sorger, Lijie Grace Zhang
3D printing has shown promise for neural regeneration by providing customized nerve scaffolds to structurally support and bridge the defect gap as well as deliver cells or various bioactive substances. Low-level light therapy (LLLT) exhibits positive effects on rehabiliation of degenerative nerves and neural disorders. With this in mind, we postulate that 3D printed neural scaffold coupling with LLLT will generate a new strategy to repair neural degeneration. To achieve this goal, we applied red laser light to stimualte neural stem cells on 3D printed scaffolds and investigated the subsequent cell response with respect to cell proliferation and differentiation...
April 12, 2017: Biofabrication
https://www.readbyqxmd.com/read/28345122/effect-of-laser-on-pain-relief-and-wound-healing-of-recurrent-aphthous-stomatitis-a-systematic-review
#9
REVIEW
Valerie G A Suter, Sophia Sjölund, Michael M Bornstein
The aim of this systematic review was to assess a potential benefit of laser use in the treatment of recurrent aphthous stomatitis (RAS). The primary outcome variables were pain relief, duration of wound healing and reduction in episode frequency. A PICO approach was used as a search strategy in Medline, Embase and Cochrane databases. After scanning and excluding titles, abstracts and full texts, 11 studies (ten RCTs and one non-randomised controlled trial) were included. Study selection and data extraction was done by two observers...
March 27, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28337885/role-of-diode-lasers-in-oro-facial-pain-management
#10
F Javed, S V Kellesarian, G E Romanos
With the increasing use of low level laser therapy (LLLT) in clinical dentistry, the aim of the present study was to assess the effectiveness of diode lasers in the management of orofacial pain. Indexed databases were searched without language and time restrictions up to and including July 2016 using different combinations of the following key words: oral, low level laser therapy, dental, pain, diode lasers, discomfort and analgesia. From the literature reviewed it is evident that LLLT is effective compared to traditional procedures in the management of oro-facial pain associated to soft tissue and hard tissue conditions such as premalignant lesions, gingival conditions and dental extractions...
January 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28337884/neurochemical-effects-of-photobiostimulation-in-the-trigeminal-ganglion-after-inferior-alveolar-nerve-injury
#11
D O Martins, F M Santos, L R G Britto, J B D Lemos, M Chacur
Orofacial pain is associated with peripheral and central sensitization of trigeminal nociceptive neurons. Nerve injury results in release of chemical mediators that contribute to persistent pain conditions. The activation of the transient receptor potential vanilloid 1 (TRPV1), promotes release of calcitonin gene-related peptide (CGRP) and substance P (SP) from trigeminal nerve terminals. CGRP and SP contribute to the development of peripheral hyperalgesia. The expression of SP and CGRP by primary afferent neurons is rapidly increased in response to peripheral inflammation...
January 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28337563/role-of-low-level-laser-therapy-added-to-facial-expression-exercises-in-patients-with-idiopathic-facial-bell-s-palsy
#12
Banu Ordahan, Ali Yavuz Karahan
The aim of the present study was to investigate the efficacy of low-level laser therapy in conjunction with conventional facial exercise treatment on functional outcomes during the early recovery period in patients with facial paralysis. Forty-six patients (mean age 41 ± 9.7 years; 40 women and 6 men) were randomized into two groups. Patients in the first group received low-level laser treatment as well as facial exercise treatment, while patients in the second group participated in facial exercise intervention alone...
March 23, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28328705/novel-approach-to-treating-androgenetic-alopecia-in-females-with-photobiomodulation-low-level-laser-therapy
#13
Shelly Friedman, Patricia Schnoor
BACKGROUND: Photobiomodulation, also referred to as low-level laser therapy (LLLT), has been studied and used for (among other diseases) the promotion of hair regrowth. OBJECTIVE/MATERIALS AND METHODS/RESULTS: A clinical study was developed to define the physiologic effects that occur when the human hair follicle and surrounding tissue structures are exposed to laser light using a novel device that is fitted with an array of laser diode sources operating at 650 nm and placed inside a sports cap to promote discretion while in use...
March 21, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28301678/effectiveness-of-adjunctive-interventions-for-accelerating-orthodontic-tooth-movement-a-systematic-review-of-systematic-reviews
#14
REVIEW
Jianru Yi, Jiani Xiao, Hanshi Li, Yu Li, Xiaobing Li, Zhihe Zhao
This study was aimed to summarize published systematic reviews that assess the effects of adjunctive interventions on the acceleration of orthodontic tooth movement (OTM). Electronic and manual searches were performed up to Aug 2016. Systematic reviews investigating the impact of adjunctive techniques on the promotion of OTM were included. The methodological quality of the included reviews was evaluated using the AMSTAR scale. The quality of evidence for each intervention was assessed using GRADE. The Jadad decision algorithm was used to select a study to provide body evidence from discordant reviews on the same intervention...
March 16, 2017: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/28294697/efficacy-of-low-level-laser-therapy-in-subjective-tinnitus-patients-with-temporomandibular-disorders
#15
Nermin Demirkol, Aslihan Usumez, Mehmet Demirkol, Fatih Sari, Cihan Akcaboy
OBJECTIVE AND BACKGROUND: Tinnitus is an apparent sound, perceived in the ear with no stimulus. It has been described as a sound originating from the brain. It affects 17% of the general population. Etiological factors for tinnitus include temporomandibular joint disorders (TMJ, TMD) and Costen's syndrome. The aim of treatment is to eliminate the tinnitus or at least decrease its apparent volume. MATERIALS AND METHODS: In total, 46 patients referred to our department with bilateral subjective tinnitus with TMDs were selected for this study...
March 14, 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28294694/the-effects-of-transcutaneous-and-intraoral-low-level-laser-therapy-after-extraction-of-lower-third-molars-a-randomized-single-blind-placebo-controlled-dual-center-study
#16
Sevil Altundag Kahraman, Sedat Cetiner, Robert A Strauss
OBJECTIVE AND BACKGROUND: The surgical removal of impacted third molars is one of the most common procedures performed by oral and maxillofacial surgeons. The purpose of this study is to determine whether either transcutaneous or intraoral low-level laser therapy (LLLT) reduces postoperative pain and assists in the healing of mandibular third molar extraction. MATERIALS AND METHODS: This randomized, placebo controlled, single-blind, split-mouth design study was conducted on 60 patients with full bony impacted similar position mandibular third molars bilaterally...
March 14, 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28292696/influence-of-low-level-laser-therapy-on-the-healing-of-human-bone-maxillofacial-defects-a-systematic-review
#17
Carolina Dos Santos Santinoni, Hiskell Francine Fernandes Oliveira, Victor Eduardo de Souza Batista, Cleidiel Aparecido Araujo Lemos, Fellippo Ramos Verri
PURPOSE: This systematic review evaluates the effectiveness of low-level laser therapy (LLLT) to enhance maxillofacial area bone repair. METHODS: A comprehensive search of studies published up to February 2017 and listed in PubMed/MEDLINE, Scopus, and Cochrane Library databases was performed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. RESULTS: The 15 selected studies evaluated a total of 374 patients (mean age, 28...
March 7, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28285410/epithelial-cell-enhanced-metabolism-by-low-level-laser-therapy-and-epidermal-growth-factor
#18
Fernanda Gonçalves Basso, Taisa Nogueira Pansani, Lais Medeiros Cardoso, Mariana Citta, Diana Gabriela Soares, Débora Salles Scheffel, Josimeri Hebling, Carlos Alberto de Souza Costa
Reepithelialization and wound closure are the desired outcome for several ulcerative conditions. Such resolution reduces the possibility of wound contamination and maintenance of the injury and improves the reestablishment of tissue morphology and functions. Investigators are seeking adjuvant therapies that can accelerate wound healing and are developing new strategies for clinical applications. This study compared the effects of epidermal growth factor (EGF) application and low-level laser therapy (LLLT) on cultured epithelial cells...
March 11, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28280999/histomorphologic-and-ultrastructural-recovery-of-myopathy-in-rats-treated-with-low-level-laser-therapy
#19
Natalia Servetto, David Cremonezzi, Juan Carlos Simes, Antonio Di Pietro, Vilma R Campana
The purpose of the present work was to study the effect of low-level laser therapy (LLLT): helium-neon (He-Ne) and gallium arsenide (Ga-As) laser on the histomorphology of muscle and mitochondria in experimental myopathy in rats. Thirty Suquía strain female rats were distributed in groups: (A) control (intact), (B) injured, (C) injured and treated with He-Ne laser, (D) injured and treated with Ga-As laser, (E) irradiated with He-Ne laser on the non-injured muscle, and (F) irradiated with Ga-As laser on the non-injured muscle...
March 9, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28279122/biochemical-changes-induced-by-grapeseed-extract-and-low-level-laser-therapy-administration-during-intraoral-wound-healing-in-rat-liver-an-experimental-and-in-silico-study
#20
Mehmet Erman Erdemli, Ramin Ekhteiari Salmas, Serdar Durdagi, Hasan Akgul, Mehmet Demirkol, Zeynep Aksungur, Zeliha Selamoglu
In the present study, the changes that occur in rat liver tissue as a result of the use of grapeseed extract (GSE) and low level laser therapy (LLLT) in intraoral wound healing are analyzed using biochemical parameters. Diode laser application groups received 8 J/cm(2) dose LLLT once a day for 4 days (810 nm wavelength, continuous mode, 0.25 W, 9 sec.). As a result of the biological parameter analysis, it was determined that the oxidative damage caused by the intraoral wounds and recovery period on 7(th) and 14(th) days could be substantially removed with GSE applications that have antioxidant capacity especially in rat liver tissue...
March 9, 2017: Journal of Biomolecular Structure & Dynamics
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