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https://www.readbyqxmd.com/read/28716393/combine-effect-of-chondroitinase-abc-and-low-level-laser-660nm-on-spinal-cord-injury-model-in-adult-male-rats
#1
Atousa Janzadeh, Arash Sarveazad, Mahmoud Yousefifard, Sima Dameni, Fazel Sahraneshin Samani, Kobra Mokhtarian, Farinaz Nasirinezhad
After spinal cord injury (SCI) there are many recoveries inhibiting factors such as chondroitin sulfate proteoglycan (CSPG) and inflammation. The present study investigated the combinational effect of low level laser therapy (LLLT) as anti-inflammatory agent and Chondroitinase ABC (ChABC) enzyme as CSPG digesting factor on spinal cord after injury. This study performed on 44 male Wistar rats, spinal cord injury induced by a clip compression injury. Animals received two-weeks treatment of 660nm low level laser (LLL) and intraspinal injection of 1μg ChABC...
July 14, 2017: Neuropeptides
https://www.readbyqxmd.com/read/28691417/effect-of-endovascular-coronary-low-level-laser-therapy-during-angioplasty-on-the-release-of-endothelin-1-and-nitric-oxide
#2
Arkadiusz Derkacz, Alicja Szymczyszyn, Ewa Szahidewicz-Krupska, Marcin Protasiewicz, Rafał Poręba, Adrian Doroszko
BACKGROUND: NO and endothelin-1 are potentially significant factors contributing to the pathogenesis of post-angioplasty restenosis. It may be postulated that LLLT can favourably influence the process of restenosis by affecting those factors. OBJECTIVES: The aim of the study was to evaluate the effect of low-level laser therapy (LLLT) applied during percutaneous coronary intervention (PCI) on the factors participating in the homeostasis of vascular tone - nitric oxide (NO) and endothelin-1...
June 27, 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28690083/analgesic-effects-of-preinjection-low-level-laser-light-therapy-lllt-before-third-molar-surgery-a-double-blind-randomized-controlled-trial
#3
Jacco G C Tuk, Arjen J van Wijk, Ine C Mertens, Zühal Keleş, Jérôme A H Lindeboom, Dan M J Milstein
OBJECTIVE: The aim of this study was to evaluate the analgesic effects of low-level laser therapy (LLLT) on preinjection sites in patients scheduled for third molar removal. STUDY DESIGN: This double-blind randomized controlled trial included 163 healthy patients undergoing third molar extractions. The study participants were randomly divided into an LLLT and a placebo group. Objective and subjective data sets were obtained from physiologic feedback (heart rate and sweat response) and a questionnaire, respectively...
May 4, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28688752/comparison-of-effects-of-lllt-and-lipus-on-fracture-healing-in-animal-models-and-patients-a-systematic-review
#4
REVIEW
Mohammad Bayat, Amarjit Virdi, Reza Jalalifirouzkouhi, Fatemehalsadat Rezaei
The aim of this paper is to study the in vivo potency of low-level laser therapy (LLLT) and low intensity pulsed ultrasound (LIPUS) alone, accompanied by bone grafts, or accompanied by other factors on fracture healing in animal models and patients. In this paper, we aim to systematically review the published scientific literature regarding the use of LLLT and LIPUS to accelerate fracture healing in animal models and patients. We searched the PubMed database for the terms LLLT or LIPUS and/or bone, and fracture...
July 5, 2017: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/28688677/long-term-survival-of-a-randomized-phase-iii-trial-of-head-and-neck-cancer-patients-receiving-concurrent-chemoradiation-therapy-with-or-without-low-level-laser-therapy-lllt-to-prevent-oral-mucositis
#5
Héliton S Antunes, Daniel Herchenhorn, Isabele A Small, Carlos M M Araújo, Celia Maria Pais Viégas, Gabriela de Assis Ramos, Fernando L Dias, Carlos G Ferreira
BACKGROUND: The impact of low-level laser therapy (LLLT) to prevent oral mucositis in patients treated with exclusive chemoradiation therapy remains unknown. This study evaluated the overall, disease-free and progression-free survival of these patients. METHODS: Overall, disease-free and progression-free survival of 94 patients diagnosed with oropharynx, nasopharynx, and hypopharynx cancer, who participated on a phase III study, was evaluated from 2007 to 2015. The patients were subjected to conventional radiotherapy plus cisplatin every 3weeks...
August 2017: Oral Oncology
https://www.readbyqxmd.com/read/28682676/a-double-blind-placebo-controlled-randomized-evaluation-of-the-effect-of-low-level-laser-therapy-on-venous-leg-ulcers
#6
Julian Vitse, Farid Bekara, Stephanie Byun, Christian Herlin, Luc Teot
This study aimed to determine the effect of low-level laser therapy (LLLT) on chronic venous leg ulcers (VLUs). A double-blinded prospective randomized controlled trial was conducted to compare incidence of complete wound closure, ulcer size and pain reduction in patients randomized to 24 treatments of placebo or LLLT (635 nm) over 12 weeks. Patients presented with a 6-week history of VLUs ranging in size from 5 to 20 cm(2). Venous origin was confirmed by Doppler ultrasound and an ankle brachial index of 0...
March 2017: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/28681933/effect-of-low-level-laser-therapy-and-oxytocin-on-osteoporotic-bone-marrow-derived-mesenchymal-stem-cells
#7
Somaye Fallahnezhad, Abbas Piryaie, Hasan Darbandi, Abdollah Amini, Seyed Kamran Ghorishi, Reza Jalalifirouzkouhi, Mohammad Bayat
Postmenopausal osteoporosis (OP) is a major concern for public health. Low-level laser therapy (LLLT) has a positive effect on the health of bone marrow mesenchymal stem cells (BMMSCs). The purpose of this study is to evaluate the influence of LLLT and oxytocin (OT) incubation-individually and in combination-on osteoporotic BMMSCs in ovariectomized rats. Twelve female rats were randomized into two groups to undergo either a sham surgery (sham group) or ovariectomy-induced osteoporosis OP (OVX group). MSCs harvested from the BM of healthy and OVX rats underwent culture expansion...
July 6, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28681084/photobiomodulation-therapy-action-in-wound-repair-skin-induced-in-aged-rats-old-time-course-of-biomarkers-inflammatory-and-repair
#8
Franciane Barbieri Fiorio, Solange Almeida Dos Santos, Caroline Sobral de Melo Rambo, Camila Guerra Dalbosco, Andrey Jorge Serra, Brunno Lemes de Melo, Ernesto Cesar Pinto Leal-Junior, Paulo de Tarso Camillo de Carvalho
Previous studies have discussed an inverse correlation between age and wound healing, because it relates to the association of aging with a gradual decrease in healing capacity. Treatment with photobiomodulation therapy (PBMT) improves wound healing by inducing increases in mitotic activity, numbers of fibroblasts, collagen synthesis, and neovascularization. Therefore, this study aimed to evaluate the effects of PBMT in cutaneous wound healing in aged rats. A punch biopsy of 8 mm in diameter was performed to produce a skin wound...
July 5, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28671718/antinociceptive-effects-of-low-level-laser-therapy-at-3-and-8%C3%A2-j-cm-2-in-a-rat-model-of-postoperative-pain-possible-role-of-endogenous-opioids
#9
Fabio C Pereira, Julia R Parisi, Caio B Maglioni, Gabriel B Machado, Paulino Barragán-Iglesias, Josie R T Silva, Marcelo L Silva
Low-level laser therapy (LLLT) is the direct application of light to stimulate cell responses (photobiomodulation) to promote tissue healing, reduce inflammation, and induce analgesia; the molecular basis for these effects of LLLT remains unclear. The objective of this study was to evaluate the analgesic effect of LLLT in the rat plantar incision model of postoperative pain as well as to investigate some of the possible mechanisms involved in this effect. Wistar rats were submitted to plantar incision and treated with LLLT (830 nm, continuous-mode, 30 mW/cm(2) , 1-12 J/cm(2) )...
July 3, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28652897/low-level-laser-therapy-in-russia-history-science-and-practice
#10
REVIEW
Sergey Vladimirovich Moskvin
In Russia (formerly USSR) study of biomodulation action (BMA) mechanisms of low-intensity laser irradiation (LILI) began in 1964, immediately after the development of lasers. During the period from 1965 to 1972 several dozens of scientific conferences were held, hundreds of studies were published. Generally, secondary mechanisms and results of LILI effect on patients with various diseases were studied. This data was immediately implemented into practical medicine in the fields of oncology, surgery, dermatology and dentistry, and since 1974 low level laser therapy (LLLT) is included in the standard of state medical care...
2017: Journal of Lasers in Medical Sciences
https://www.readbyqxmd.com/read/28643927/co2-low-level-laser-therapy-has-an-early-but-not-delayed-pain-effect-during-experimental-tooth-movement
#11
T Deguchi, D G Kim, H Kamioka
OBJECTIVES: To test the hypothesis that the use of low-level laser therapy (LLLT) reduces elevated pain by controlling the release of neurochemicals during orthodontic tooth movement. SETTING AND SAMPLE POPULATION: Department of Orthodontics and Dentofacial Orthopedics, Okayama University. Sixty-five Sprague Dawley rats were subjected to tooth movement and LLLT. MATERIALS AND METHODS: Adult Sprague Dawley rats were used in this study. Groups included day 0 controls, irradiation only controls and with or without irradiation sacrificed at 1, 3, 5, 7 and 14 days after tooth movement (n=5 each, total n=65)...
June 2017: Orthodontics & Craniofacial Research
https://www.readbyqxmd.com/read/28633773/magnetic-resonance-imaging-and-clinical-outcomes-of-laser-therapy-ultrasound-therapy-and-extracorporeal-shock-wave-therapy-for-treatment-of-plantar-fasciitis-a-randomized-controlled-trial
#12
Aslihan Ulusoy, Lale Cerrahoglu, Sebnem Orguc
We determined and compared the effectiveness of low-level laser therapy (LLLT), therapeutic ultrasound (US) therapy, and extracorporeal shock wave therapy (ESWT) using magnetic resonance imaging (MRI). We performed a randomized, prospective, comparative clinical study. A total of 60 patients with a diagnosis of chronic plantar fasciitis were divided randomly into 3 treatment groups: group 1 underwent 15 sessions of LLLT (8 J/cm(2); 830 nm); group 2 underwent 15 sessions of continuous US (1 mHz; 2 W/cm(2)); and group 3 underwent 3 sessions of ESWT (2000 shocks)...
July 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28622041/the-effects-of-low-level-laser-therapy-on-the-healing-of-bone-defects-in-streptozotocin-induced-diabetic-rats-a-histological-and-morphometric-evaluation
#13
Senem Yildirimturk, Yigit Sirin, Merva Soluk Tekkesin, Gokhan Gurler, Deniz Firat
BACKGROUND: The aim of the present study was to evaluate the effects of LLLT on the healing of bone defects in rats with streptozotocin (STZ) induced DM. METHODS: 28 male Sprague-Dawley rats were used in this study. 14 animals received a single dose of STZ intraperitoneally (65 mg/kg) to induce Type I DM, whereas others were injected only with sterile saline solution. Four weeks later, standard bone defects were created in the tibiae of rats. Surgical wounds in one group from each of the diabetic and non-diabetic animals were irradiated with diode laser for every other day for 4 weeks and they were described as DM+LLLT and CONT+LLLT groups, respectively...
June 16, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/28621568/presenting-a-method-to-improve-bone-quality-through-stimulation-of-osteoporotic-mesenchymal-stem-cells-by-low-level-laser-therapy
#14
Mohammad Bayat, Ali Jalalifirouzkouhi
OBJECTIVE: This review aims to present a method to improve bone quality through stimulation of osteoporotic mesenchymal stem cells (MSCs) by low-level laser therapy (LLLT). BACKGROUND: Osteoporosis (OP) is characterized by decreased bone mass and bone strength, which results in an increased incidence of bone fractures. These fractures often lead to additional disability and mortality. Osteoporotic MSCs have reduced osteogenic differentiation when cultured in their standard differentiation media...
June 15, 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28621287/ibuprofen-and-low-level-laser-therapy-for-pain-control-during-fixed-orthodontic-therapy-a-systematic-review-of-randomized-controlled-trials-and-meta-analysis
#15
Faezeh Eslamipour, Saeed R Motamedian, Fahimeh Bagheri
INTRODUCTION: To systematically review high-quality randomized controlled trials (RCTs) and meta-analysis on the effectiveness of use of ibuprofen and low-level laser therapy (LLLT) for pain control during fixed orthodontic appliance therapy. MATERIALS AND METHODS: A web-based systematic search of PubMed and Medline database using relevant keywords was performed in August 2016 limited to the English language studies. Based on inclusion and exclusion criteria, RCTs utilizing blind approach were selected...
June 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28603084/biosilicate-plga-osteogenic-effects-modulated-by-laser-therapy-in-vitro-and-in-vivo-studies
#16
K R Fernandes, A M P Magri, H W Kido, J R Parisi, L Assis, K P S Fernandes, R A Mesquita-Ferrari, V C Martins, A M Plepis, E D Zanotto, O Peitl, A C M Renno
The main purpose of the present work was to evaluate if low laser level therapy (LLLT) can improve the effects of Biosilicate®/PLGA (BS/PLGA) composites on cell viability and bone consolidation using a tibial defects of rats. The composites were characterized by scanning electron microscope (SEM) and reflection Fourier transform infrared spectrometer (FTIR). For the in vitro study, fibroblast and osteoblast cells were seeded in the extract of the composites irradiated or not with LLLT (Ga-Al-As, 808nm, 10J/cm(2)) to assess cell viability after 24, 48 and 72h...
June 3, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28584230/photobiomodulation-of-human-dermal-fibroblasts-in-vitro-decisive-role-of-cell-culture-conditions-and-treatment-protocols-on-experimental-outcome
#17
C Mignon, N E Uzunbajakava, B Raafs, N V Botchkareva, D J Tobin
Photobiomodulation-based (LLLT) therapies show tantalizing promise for treatment of skin diseases. Confidence in this approach is blighted however by lamentable inconsistency in published experimental designs, and so complicates interpretation. Here we interrogate the appropriateness of a range of previously-reported treatment parameters, including light wavelength, irradiance and radiant exposure, as well as cell culture conditions (e.g., serum concentration, cell confluency, medium refreshment, direct/indirect treatment, oxygen concentration, etc...
June 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28580494/efficacy-of-low-level-laser-therapy-in-carpal-tunnel-syndrome-management-a-systematic-review-and-meta-analysis
#18
Amira Hassan Bekhet, Basma Ragab, Abdelrahman Ibrahim Abushouk, Ahmed Elgebaly, Olfat Ibrahim Ali
We performed this meta-analysis to investigate the efficacy of low-level laser therapy (LLLT), a physiotherapy modality with anti-inflammatory and analgesic effects, in the management of mild-to-moderate carpal tunnel syndrome (CTS). We searched PubMed, Web of Knowledge, Scopus, Cochrane Central, and Virtual Health Library for randomized controlled trials (RCTs) that compared the effects of LLLT with or without splinting versus placebo on functional and electromyographic outcomes in CTS. All outcomes were pooled as mean differences (MD) under the inverse variance or random effects model, using the statistical add-in (MetaXL, version 5...
June 5, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28579190/effect-of-low-level-laser-therapy-lllt-and-light-emitting-diodes-ledt-applied-during-combined-training-on-performance-and-post-exercise-recovery-protocol-for-a-randomized-placebo-controlled-trial
#19
Aryane Flauzino Machado, Jéssica Kirsch Micheletti, Franciele Marques Vanderlei, Fabio Yuzo Nakamura, Ernesto Cesar Pinto Leal-Junior, Jayme Netto Junior, Carlos Marcelo Pastre
BACKGROUND: Previous studies have shown positive results of phototherapy for improving performance and accelerating recovery; however, the effects of phototherapy during training and after a primary adaptation remain unclear. The aim of this randomized controlled trial is to analyze the effects of phototherapy and combined training on clinical, functional, and psychological outcomes and on vascular endothelial growth factor. METHODS: This randomized placebo-controlled trial by stratified sample will involve 45 healthy male participants...
July 2017: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/28578368/effect-of-pre-operatory-low-level-laser-therapy-on-pain-swelling-and-trismus-associated-with-third-molar-surgery
#20
M Petrini, M Ferrante, P Trentini, G Perfetti, G Spoto
BACKGROUND: The extraction of impacted third molars is commonly associated to pain, edema, trismus, limited jaw opening and movements. The aim of this retrospective study is to verify if pre-surgical low-level laser therapy (LLLT) associated with the extraction of impacted lower third molars could add benefits to the postoperative symptoms respect LLLT performed only after surgery. MATERIAL AND METHODS: Data from 45 patients subjected to a surgical extraction of lower third molars were pooled and divided into three groups...
July 1, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
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