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https://www.readbyqxmd.com/read/29764213/a-novel-non-invasive-strategy-for-low-level-laser-induced-cancer-therapy-by-using-new-ag-zno-and-nd-zno-functionalized-reduced-graphene-oxide-nanocomposites
#1
Saeed Jafarirad, Ebrahim Hammami Torghabe, Seyed Hosseyn Rasta, Roya Salehi
In the present research, an effective drug-free approach was developed to kill MCF7 breast cancer cells using low-level laser therapy (LLLT) combined with reduced graphene oxide (rGO)-based hybrid nanocomposites (NCs). Here, fruit extract of Rosa canina was used for the first time to obtain the rGO/ZnO, Ag-ZnO/rGO and Nd-ZnO/rGO NCs by green synthesis. Physico/photochemical properties of these NCs were evaluated using FTIR, XRD, Raman, XPS, SEM/EDX, UV-Vis, DLS and AFM. The potential of the as-synthesized NCs on ROS generating and antioxidant activity were assessed by DPPH...
May 15, 2018: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/29751100/low-level-laser-therapy-with-850-nm-recovers-salivary-function-via-membrane-redistribution-of-aquaporin-5-by-reducing-intracellular-ca-2-overload-and-er-stress-during-hyperglycemia
#2
Raktim Biswas, Jin Chul Ahn, Jeong Hwan Moon, Jungbin Kim, Young-Hoon Choi, So Young Park, Phil-Sang Chung
The overall goal is to study the effect of low-level laser therapy (LLLT) on membrane distribution of major water channel protein aquaporin 5 (AQP5) in salivary gland during hyperglycemia. Par C10 cells treated with high glucose (50 mM) showed a reduced membrane distribution of AQP5. The functional expression of AQP5 was down regulated due to intracellular Ca2+ overload and ER stress. This reduction in AQP5 expression impairs water permeability and therefore results in hypo-salivation. A reduced salivary flow was also observed in streptozotocin (STZ)-induced diabetic mice model and the expression of AQP5 and phospho-AQP5 was down regulated...
May 8, 2018: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29730821/evaluation-of-the-low-level-laser-therapy-application-parameters-for-skin-burn-treatment-in-experimental-model-a-systematic-review
#3
Patricia Brassolatti, Ana Laura Martins de Andrade, Paulo Sérgio Bossini, Albaiza Nicoletti Otterço, Nivaldo Antônio Parizotto
Burn is defined as a traumatic injury of thermal origin, which affects the organic tissue. Low-level laser therapy (LLLT) has gained great prominence as a treatment in this type of injury; however, the application parameters are still controversial in the literature. The aims of this study were to review the literature studies that use LLLT as a treatment in burns conducted in an experimental model, discuss the main parameters used, and highlight the benefits found in order to choose an appropriate therapeutic window to be applied in this type of injury...
May 5, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29728552/the-efficacy-of-low-level-laser-therapy-on-pain-caused-by-placement-of-the-first-orthodontic-archwire-a-clinical-study
#4
Javeriya Nahin, Faisal Arshad, Bharathi V Srinivas, Shashi Kumar, Nagamangala K Lokesh
Aim: This study was conducted to clinically evaluate the effect of low-level laser therapy (LLLT) as a method of reducing pain reported by patients after placement of their first orthodontic archwires. Materials and methods: A sample of 10 patients with an age group of 12 to 26 years with moderate-to-severe anterior crowding was selected. Each patient was assigned to an experimental group (left quadrant with laser therapy) and a control group (right quadrant with no laser therapy). Low-level laser therapy was given immediately after the placement of initial archwire...
April 1, 2018: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/29725945/low-level-laser-irradiation-modifies-the-effect-of-hyperglycemia-on-adhesion-molecule-levels
#5
Krzysztof Góralczyk, Justyna Szymańska, Łukasz Gryko, Jacek Fisz, Danuta Rość
Endothelium plays a key role in maintaining vascular homeostasis by secreting active factors involved in many biological processes such as hemostasis, angiogenesis, and inflammation. Hyperglycemia in diabetic patients causes dysfunction of endothelial cells. Soluble fractions of adhesion molecules like sE-selectin and vascular cell adhesion molecule (sVCAM) are considered as markers of endothelial damage. The low-level laser therapy (LLLT) effectively supports the conventional treatment of vascular complications in diabetes, for example hard-to-heal wounds in patients with diabetic foot syndrome...
May 3, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29713842/effects-of-low-level-laser-therapy-on-soft-and-hard-tissue-healing-after-endodontic-surgery
#6
Revnak Metin, Ufuk Tatli, Burcu Evlice
The aim of this prospective study was to examine possible benefits of low-level laser therapy (LLLT) on soft and hard tissue healing after endodontic surgery. Seventy-six endo-surgery cases on maxillary incisors were included. The patients were assigned randomly into control and laser groups. In the laser group, gallium-aluminum-arsenide (GaAlAs) diode laser irradiation (810 nm, 129 mW, 3.87 J/cm2 ) was performed immediately after surgery and daily for postoperative 7 days from buccal and palatal surfaces (5 min for each side)...
April 30, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29697718/efficacy-of-low-level-laser-therapy-in-the-treatment-of-temporomandibular-myofascial-pain-a-systematic-review-and-meta-analysis
#7
Fernando M Munguia, John Jang, Mahmoud Salem, Glenn T Clark, Reyes Enciso
AIMS: To conduct a systematic review and meta-analysis to determine the efficacy of low-level laser therapy (LLLT) in treating temporomandibular myofascial pain in adults compared to laser placebo. METHODS: Randomized, placebo-controlled studies were identified by a search on March 2, 2016 and updated on February 9, 2017 in the PubMed, Web of Science, and Cochrane Library databases. Three of the authors assessed the studies for risk of bias. Outcomes included pain reduction on a visual analog scale (VAS) and interincisal opening...
April 25, 2018: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/29697148/influence-of-class-iv-laser-therapy-on-the-outcomes-of-tibial-plateau-leveling-osteotomy-in-dogs
#8
S Michelle Renwick, Alasdair I Renwick, David C Brodbelt, John Ferguson, Humberto Abreu
OBJECTIVE: To determine the effects of low-level laser therapy (LLLT) on clinical outcomes in dogs with cranial cruciate ligament disease treated with tibial plateau leveling osteotomy (TPLO). STUDY DESIGN: Randomized, placebo-controlled clinical trial. Owners and surgeons (care providers and assessors) were masked. ANIMALS: Ninety-five dogs were admitted for TPLO and assigned to 1 of 2 groups, laser group (LG; n = 51) or placebo group (PG; n = 44)...
April 26, 2018: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/29696113/prolotherapy-and-low-level-laser-therapy-a-synergistic-approach-to-pain-management-in-chronic-osteoarthritis
#9
REVIEW
Vinicius Tieppo Francio, Robert S Dima, Chris Towery, Saeid Davani
Regenerative injection therapy and low level laser therapy are alternative remedies known for their success in the treatment and symptomatic management of chronic musculoskeletal conditions. In response to the growing demand for alternative therapies in the face of the opioid epidemic, the authors conduct a literature review to investigate the potential for prolotherapy and LLLT to be used adjunctively to manage chronic osteoarthritis (OA). OA is a degenerative chronic musculoskeletal condition on the rise in North America, and is frequently treated with opioid medications...
October 2017: Anesthesiology and Pain Medicine
https://www.readbyqxmd.com/read/29692828/evaluation-of-four-pulpotomy-techniques-in-primary-molars-a-randomized-controlled-trial
#10
Ghassem Ansari, Seyyedeh Pouya Morovati, Saeed Asgary
Introduction: This trial was designed to evaluate the clinical and radiographic success rates of calcium-enriched mixture (CEM) cement with and without low level laser therapy (LLLT) and compare them to that of formocresol (FC) and ferric sulfate (FS) in primary molar pulpotomies. Methods and Materials: This randomized clinical trial was conducted on a total of 160 teeth selected from 40 patients aged 3-9 years. Patients with at least four primary molars needing pulpotomy, were included in order to have each tooth assigned randomly in one of the four following groups; FC, FS, CEM, and LLLT/CEM...
2018: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/29686745/low-level-laser-therapy-reduces-lung-inflammation-in-an-experimental-model-of-chronic-obstructive-pulmonary-disease-involving-p2x7-receptor
#11
Gabriel da Cunha Moraes, Luana Beatriz Vitoretti, Auriléia Aparecida de Brito, Cintia Estefano Alves, Nicole Cristine Rigonato de Oliveira, Alana Dos Santos Dias, Yves Silva Teles Matos, Manoel Carneiro Oliveira-Junior, Luis Vicente Franco Oliveira, Renata Kelly da Palma, Larissa Carbonera Candeo, Adriana Lino-Dos-Santos-Franco, Anna Carolina Ratto Tempestine Horliana, João Antonio Gimenes Júnior, Flavio Aimbire, Rodolfo Paula Vieira, Ana Paula Ligeiro-de-Oliveira
Chronic obstructive pulmonary disease (COPD) is a progressive disease characterized by irreversible airflow limitation, airway inflammation and remodeling, and enlargement of alveolar spaces. COPD is in the top five leading causes of deaths worldwide and presents a high economic cost. However, there are some preventive measures to lower the risk of developing COPD. Low-level laser therapy (LLLT) is a new effective therapy, with very low cost and no side effects. So, our objective was to investigate if LLLT reduces pulmonary alterations in an experimental model of COPD...
2018: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/29658096/effect-of-low-level-laser-and-low-intensity-pulsed-ultrasound-therapy-on-bone-remodeling-during-orthodontic-tooth-movement-in-rats
#12
Mohammed Mahmood Jawad Alazzawi, Adam Husein, Mohammad Khursheed Alam, Rozita Hassan, Rumaizi Shaari, Ahmad Azlina, M S Salzihan
BACKGROUND: Quality bone regeneration, which leads to the improvement of bone remodeling, is essential for orthodontic treatment. In order to improve bone regeneration and increase the amount of tooth movement, different techniques have been implemented. The object of this study is to compare the effects of low-level laser therapy (LLLT), low-intensity pulsed ultrasound (LIPUS), and their combination on bone remodeling during orthodontic tooth movement. METHODS: Eighty (80) male, 6-week-old Sprague Dawley rats were grouped in to four groups, the first group was irradiated with (940 nm) diode laser, second group with LIPUS, and third group with combination of both LLLT and LIPUS...
April 16, 2018: Progress in Orthodontics
https://www.readbyqxmd.com/read/29643585/electromyographic-evaluation-of-a-low-level-laser-protocol-for-the-treatment-of-temporomandibular-disorder-a-randomized-controlled-blind-trial
#13
Camila Haddad Leal de Godoy, Lara Jansiski Motta, Eugenio Jose Garcia, Kristianne Porta Santos Fernandes, Raquel Agnelli Mesquita-Ferrari, Ravana Angelini Sfalcin, Pamella de Barros Motta, Fabiano Politti, Sandra Kalil Bussadori
[Purpose] Problems involving the temporomandibular joint and associated structures can lead to temporomandibular disorder (TMD). The aim of the present study was to evaluate muscle activity in individuals with a diagnosis of TMD before and after treatment with low-level laser therapy (LLLT) through the use of electromyography (EMG). [Subjects and Methods] Male and female individuals aged 14 to 23 years were evaluated. TMD was determined by a clinical examination and the administration of the Research Diagnostic Criteria for Temporomandibular Disorders, followed by the evaluation of sensitivity to palpation of the masseter and anterior temporal muscles as well as the EMG determination of muscle activity...
December 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/29627888/the-effect-of-high-intensity-versus-low-level-laser-therapy-in-the-management-of-plantar-fasciitis-a-randomized-clinical-trial
#14
Banu Ordahan, Ali Yavuz Karahan, Ercan Kaydok
We aimed to compare the efficacy of low-level laser therapy (LLLT) and high-intensity laser therapy (HILT) in the treatment of plantar fasciitis (PF). Seventy patients were randomized into either the LLLT (8 men, 27 women; mean age 48.65 ± 10.81 years) or HILT (7 men, 28 women; mean age 48.73 ± 11.41 years) groups. LLLT (904 nm) and HILT (1064 nm) were performed three times per week, over a period of 3 weeks. Each treatment combined with silicone insole and stretching exercises. Patients' pain and functional status were evaluated with Visual Analog Scale, Heel Tenderness Index, and Foot and Ankle Outcome Score before and after treatment...
April 7, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29623521/high-doses-of-laser-phototherapy-can-increase-proliferation-in-melanoma-stromal-connective-tissue
#15
Lúcio Frigo, Joseli Maria Cordeiro, Giovani Marino Favero, Durnavei Augusto Maria, Ernesto Cesar Pinto Leal-Junior, Jon Joensen, Jan Magnus Bjordal, Denise Carvalho Roxo, Rodrigo Labat Marcos, Rodrigo Alvaro Brandão Lopes-Martins
It is well established that laser phototherapy (LP) is contraindicated directly over cancer cells, due to its bio modulatory effects in cell and blood vessel proliferation. The aim of the present study was to analyze the influence of typical low-level laser therapy (LLLT) and high intensity laser therapy (HILT) and an in-between dose of 9 J on collagen fibers and blood vessels content in melanoma tumors (B16F10) implanted in mice. Melanoma tumor cells were injected in male Balb C mice which were distributed in four groups: control (no irradiated) or irradiated by 3, 9, or 21 J (150; 450, or 1050 J/cm2 )...
April 5, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29611064/comparative-effect-of-photobiomodulation-associated-with-dexamethasone-after-sciatic-nerve-injury-model
#16
Luana Gabriel de Souza, Alexandre Márcio Marcolino, Heloyse Uliam Kuriki, Elaine Cristina Dalazen Gonçalves, Marisa de Cássia Registro Fonseca, Rafael Inácio Barbosa
To analyze the effect of photobiomodulation and dexamethasone on nerve regeneration after a sciatic nerve crushing model. Twenty-six Swiss mice were divided into the following groups: naive; sham; injured, low-level laser therapy (LLLT) (660 nm, 10 J/cm2 , 0.6 J, 16.8 J total energy emitted during the 28 days of radiation, 20 s, for 28 days); dexamethasone (Dex) (local injection of 2 mg/kg for 10 consecutive days); and LLLT group associated with Dex (LLLT/Dex), with the same parameters of the other groups...
April 2, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29611063/physical-properties-of-hydrogel-wound-dressing-and-its-use-in-low-level-laser-therapy-lllt
#17
K Wachal, E Stachowska, K Korpuścińska, B Nowak, Z Krasiński
Hydrogel dressings are routinely used in the treatment of superficial skin wounds. Due to their excellent transparency, we decided to evaluate their usefulness in laser-based medical procedures. We focused on assessing selected physical properties of HydroAid hydrogel wound dressing, used for low-level laser therapy (LLLT) aka laser biostimulation procedures. For the two wavelengths of 660 and 808 nm used in the biostimulation laser POLARIS 2, a dressing transmittance of 92 and 98%, respectively, was determined...
April 2, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29607622/ischemic-oculomotor-nerve-palsy-due-to-hyaluronic-acid-filler-injection
#18
In Ho Bae, Min Sung Kim, Hoon Choi, Chan Ho Na, Bong Seok Shin
Hyaluronic acid (HA) is the most popular agent today for intradermal injections to improve wrinkles and other cosmetic defects. Ischemic necrosis due to injection of HA is one of the serious complications. Because there are many vascular branches around the nose, caution and care should be given during facial filler injection. Although the incidence is rare, blindness and permanent visual loss may occur. We describe a 29-year-old woman presented with painful erythematous swelling with violaceous patch on right periocular area and glabella after HA filler injection...
April 1, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29603903/photobiomodulation-of-freshly-isolated-human-adipose-tissue-derived-stromal-vascular-fraction-cells-by-pulsed-light-emitting-diodes-for-direct-clinical-application
#19
E Priglinger, J Maier, S Chaudary, C Lindner, C Wurzer, S Rieger, H Redl, S Wolbank, P Dungel
A highly interesting source for adult stem cells is adipose tissue, from which the stromal vascular fraction (SVF) - a heterogeneous cell population including the adipose-derived stromal/stem cells (ASC) - can be obtained. To enhance the regenerative potential of freshly isolated SVF cells low level light therapy (LLLT), was used. The effects of pulsed blue (475 nm), green (516 nm) and red light (635 nm) from light-emitting diodes (LEDs) applied on freshly isolated SVF were analyzed regarding cell phenotype, cell number, viability, adenosine triphosphate content, cytotoxicity and proliferation, but also osteogenic, adipogenic and pro-angiogenic differentiation potential...
March 31, 2018: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/29603108/should-open-excisions-and-sutured-incisions-be-treated-differently-a-review-and-meta-analysis-of-animal-wound-models-following-low-level-laser-therapy
#20
Peter Gál, Martin Bjørn Stausholm, Ivan Kováč, Erik Dosedla, Ján Luczy, František Sabol, Jan Magnus Bjordal
Although low-level laser therapy (LLLT) was discovered already in the 1960s of the twentieth century, it took almost 40 years to be widely used in clinical dermatology/surgery. It has been demonstrated that LLLT is able to increase collagen production/wound stiffness and/or improve wound contraction. In this review, we investigated whether open and sutured wounds should be treated with different LLLT parameters. A PubMed search was performed to identify controlled studies with LLLT applied to wounded animals (sutured incisions-tensile strength measurement and open excisions-area measurement)...
March 30, 2018: Lasers in Medical Science
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