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https://www.readbyqxmd.com/read/29761337/-psychogenic-non-epileptic-seizures-differential-diagnostic-features
#1
REVIEW
Philipp S Reif, Laurent M Willems, Adam Strzelczyk, Karl Martin Klein, Felix Rosenow
Psychogenic nonepileptic seizures (PNES) are to be considered in the differential diagnosis of a transient loss of consciousness. Their discrimination from syncope, epileptic seizures or vascular events can be difficult and requires profound knowledge about the semiology and clinical presentation of PNES and their differential diagnoses. Erroneous diagnoses and the resulting therapies lead to elevated morbidity, elevated costs and a poorer outcome. The aim of the present article is to provide an overview on PNES and their delineation from the clinical pictures of epilepsy and syncope...
May 14, 2018: Herzschrittmachertherapie & Elektrophysiologie
https://www.readbyqxmd.com/read/29754013/psychogenic-nonepileptic-seizures-in-adults-with-epilepsy-and-intellectual-disability-a-neglected-area
#2
Jans S van Ool, Alexandra I Haenen, Francesca M Snoeijen-Schouwenaars, Albert P Aldenkamp, Jos G M Hendriksen, H Jurgen Schelhaas, In Y Tan, Richard H C Lazeron, Nynke M G Bodde
PURPOSE: To describe the main characteristics of psychogenic nonepileptic seizures (PNES) in adults with epilepsy and intellectual disability (ID), and to analyse the differences regarding psychosocial functioning, epilepsy severity and ID between patients with PNES and a control group without PNES. METHODS: Medical records of adults with ID and epilepsy living at an epilepsy care facility (N = 240) were screened for PNES and evaluated by a neurologist. A control group consisting of patients with epilepsy and ID, without PNES, was matched according to age, sex and level of ID...
May 4, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29754012/clinical-spectrum-of-psychogenic-non-epileptic-seizures-in-children-an-observational-study
#3
Priyanka Madaan, Sheffali Gulati, Biswaroop Chakrabarty, Savita Sapra, Rajesh Sagar, Akbar Mohammad, R M Pandey, Manjari Tripathi
PURPOSE: The current study was designed to analyze the clinical spectrum of Psychogenic non-epileptic seizures (PNES) in children. METHODS: Children aged 6-16years with clinically suspected PNES, confirmed by short-term VEEG (STVEEG{video electroencephalogram}) and induction were classified as per Seneviratne classification. Stressors, associated co morbidities, Verbal IQ (Intelligence Quotient) and behavioral abnormalities were assessed using HTP(House tree person) test, DSM IV (Diagnostic and statistical manual of mental disorders) TR criteria, MISIC (Malin intelligence scale for Indian children) and CBCL (Child behaviour checklist)...
April 27, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29751354/evaluation-of-knowledge-about-epilepsy-and-attitudes-towards-patients-with-epilepsy-among-university-students-in-upper-egypt
#4
Mohamed N Thabit, Mohamed A Sayed, Magda M Ali
PURPOSE: Epilepsy is a major public health problem worldwide. There are many misconceptions about people's knowledge and attitudes about epilepsy, which influence people's behavior towards patients with epilepsy. METHODS: We conducted a cross-sectional study in Sohag University, a public Egyptian University, in Upper Egypt. We used an Arabic language designed questionnaire to assess people's knowledge about epilepsy and their attitudes towards patients with epilepsy...
May 5, 2018: Epilepsy Research
https://www.readbyqxmd.com/read/29750340/health-care-practitioners-perceptions-of-psychogenic-nonepileptic-seizures-a-systematic-review-of-qualitative-and-quantitative-studies
#5
Gregg H Rawlings, Markus Reuber
A recent systematic synthesis of qualitative research demonstrated that patients with psychogenic nonepileptic seizures (PNES) often experience unsatisfactory encounters with health care practitioners (HCPs). It is important to understand such interactions from the perspective of those responsible for delivering care. This systematic review aimed to examine the attitudes and perceptions of HCPs toward PNES. A systematic search of 3 databases (Web of Science, PubMed, and CINAHL) was conducted in November 2017...
May 11, 2018: Epilepsia
https://www.readbyqxmd.com/read/29739840/characteristics-of-children-hospitalized-for-psychogenic-nonepileptic-seizures-due-to-conversion-disorder-versus-epilepsy
#6
Sarah K Luthy, Angela F Moss, Michelle R Torok, Lisa McLeod, Karen M Wilson
OBJECTIVES: Psychogenic nonepileptic seizures (PNES) are a manifestation of conversion disorder among children but can be difficult to distinguish from epilepsy. We sought to identify characteristics that differentiate children with PNES from those with epilepsy. METHODS: We conducted a retrospective cohort study of children admitted with epilepsy or PNES to 45 children's hospitals from 2004 to 2014. Children with PNES ( n = 399) versus those with epilepsy ( n = 13 241) were compared on demographic and clinical characteristics, testing, treatment, and health care use...
May 8, 2018: Hospital Pediatrics
https://www.readbyqxmd.com/read/29730500/changes-in-antiepileptic-drug-prescribing-patterns-in-pregnant-women-with-epilepsy
#7
Kimford J Meador, Page B Pennell, Ryan C May, Elizabeth Gerard, Laura Kalayjian, Naymee Velez-Ruiz, Patricia Penovich, Jennifer Cavitt, Jaqueline French, Sean Hwang, Alison M Pack, Maria Sam, Eugene Moore, Dominic M Ippolito
OBJECTIVE: We analyzed current prescribing patterns for antiepileptic drugs (AEDs) in pregnant women with epilepsy (PWWE) at 20 USA tertiary epilepsy centers. METHODS: The Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD) study is an NIH-funded, prospective, observational, multicenter investigation of pregnancy outcomes for both mother and child, which enrolled women from December 2012 to January 2016. Inclusion criteria for PWWE included ages 14-45 years and up to 20 weeks gestational age...
May 3, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29709879/change-in-illness-perception-is-associated-with-short-term-seizure-burden-outcome-following-video-eeg-confirmation-of-psychogenic-nonepileptic-seizures
#8
David K Chen, Shirine Majmudar, Aarthi Ram, Holly C Rutherford, Melissa Fadipe, Callie B Dunn, Robert L Collins
OBJECTIVES: We aimed to evaluate whether potential changes in the patient's illness perception can significantly influence short-term seizure burden following video-electroencephalography (EEG) confirmation/explanation of psychogenic nonepileptic seizures (PNES). METHODS: Patients with PNES were dichotomized to two groups based on a five-point Symptom Attribution Scale: (a) those who prior to diagnosis perceived their seizures to be solely ("5") or mainly ("4") physical in origin (physical group) and (b) the remainder of patients with PNES (psychological group)...
April 27, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29709720/outcome-of-patients-with-psychogenic-nonepileptic-seizures-with-limited-resources-a-longitudinal-study
#9
Ali A Asadi-Pooya, Fateme Ziyaee
PURPOSE: The aim of the current study was to investigate the long-term outcome of patients with psychogenic nonepileptic seizures (PNES) and factors potentially associated with their outcome in Iran. METHODS: We investigated all patients with PNES admitted to the epilepsy monitoring unit at the Shiraz Comprehensive Epilepsy Center from 2008 through 2013. Patients included in this study had a confirmed diagnosis of PNES. In a phone call interview to the patients in December 2017, we obtained the following information: seizure outcome (seizure-free during the past 12 months or not), history of receiving any psychotherapy after confirming their diagnosis in the past, and number of psychotherapy sessions the patient had received...
April 25, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29705625/survey-of-physician-attitudes-towards-psychogenic-nonepileptic-seizures-and-driving
#10
Umer Farooq, Saeed Ahmed, Jayakrishna Madabush, Venkata Kolli, Michael Esang, Vijaya Padma Kotapati, Rizwan Ahmed, Cornel N Stanciu
BACKGROUND: Physicians from various disciplines encounter patients presenting with psychogenic nonepileptic seizures (PNES) as part of their routine clinical practice. Recommendations towards assessing fitness to drive and reporting are clearer for conditions such as neurocognitive disorders and epilepsy, but such guidelines do not exist for patients with PNES. Here, we assess physicians' attitudes towards driving for patients diagnosed with PNES. METHODS: Electronic questionnaires were sent to Neurology and Family Medicine physicians practicing at Creighton University Medical Center and Psychiatry physicians practicing at Creighton-Nebraska Psychiatry Residency Program to assess their opinion regarding driving risk when encountering PNES...
April 26, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29702410/scared-or-scarred-could-dissociogenic-lesions-predispose-to-nonepileptic-seizures-after-head-trauma
#11
REVIEW
Stoyan Popkirov, Alan J Carson, Jon Stone
A history of head injury is common in patients with psychogenic nonepileptic seizures (PNES). This association has so far been interpreted as either spurious or psychologically mediated. Biased recall and misattribution could foster illness beliefs about brain damage that promote symptom production. Furthermore, the emotional impact of head injury could induce long-term changes in stress responsivity. Lastly, maladaptive cognitive-behavioural processes involving symptom modelling and aversive conditioning, known to play a role in functional neurological disorders, could contribute to the development of PNES after head trauma...
April 14, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29696750/angelman-syndrome-in-adolescence-and-adulthood-a-retrospective-chart-review-of-53-cases
#12
Ankita Prasad, Olivia Grocott, Kimberly Parkin, Anna Larson, Ronald L Thibert
Angelman syndrome is a neurogenetic disorder with varying clinical presentations and symptoms as the individual ages. The goal of this study was to characterize changes over time in the natural history of this syndrome in a large population. We reviewed the medical records of the 53 patients who were born prior to 2000 and seen at the Angelman Syndrome Clinic at Massachusetts General Hospital to assess neurological, sleep, behavioral, gastrointestinal, orthopedic, and ophthalmologic functioning. The average age of this cohort was 24 years...
April 25, 2018: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/29665572/diagnostic-and-treatment-practices-for-psychogenic-nonepileptic-and-epileptic-seizures-in-namibia
#13
Anina du Toit, Chrisma Pretorius
PURPOSE: Information about existing healthcare resources for the management of seizures in developing countries is lacking. These countries are often poorly equipped to deal with the immense burden of costs, mortality, stigma, seizure-related disability, and comorbidities presented by seizure disorders. This study aimed to contribute to the goals of the International League Against Epilepsy (ILAE) by investigating the resources available for patients with seizure in Namibia. METHODS: Two separate surveys on the diagnostic and treatment practices for epileptic seizures (ES) and psychogenic nonepileptic seizures (PNES) were administered to private healthcare practitioners (HCPs) in Namibia...
April 13, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29644724/a-novel-missense-mutation-in-grin2a-causes-a-nonepileptic-neurodevelopmental-disorder
#14
Ana Fernández-Marmiesse, Hirofumi Kusumoto, Saray Rekarte, Iria Roca, Jin Zhang, Scott J Myers, Stephen F Traynelis, Mª Luz Couce, Luis Gutierrez-Solana, Hongjie Yuan
BACKGROUND: Mutations in the GRIN2A gene, which encodes the GluN2A (glutamate [NMDA] receptor subunit epsilon-1) subunit of the N-methyl-d-aspartate receptor, have been identified in patients with epilepsy-aphasia spectrum disorders, idiopathic focal epilepsies with centrotemporal spikes, and epileptic encephalopathies with severe developmental delay. However, thus far, mutations in this gene have not been associated with a nonepileptic neurodevelopmental disorder with dystonia. OBJECTIVES: The objective of this study was to identify the disease-causing gene in 2 siblings with neurodevelopmental and movement disorders with no epileptiform abnormalities...
April 11, 2018: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/29628295/right-temporoparietal-junction-transcranial-magnetic-stimulation-in-the-treatment-of-psychogenic-nonepileptic-seizures-a-case-series
#15
Krystyna T Peterson, Robert Kosior, Benjamin P Meek, Marcus Ng, David L Perez, Mandana Modirrousta
No abstract text is available yet for this article.
March 7, 2018: Psychosomatics
https://www.readbyqxmd.com/read/29609146/effects-of-a-psychotherapeutic-group-intervention-in-patients-with-refractory-mesial-temporal-lobe-epilepsy-and-comorbid-psychogenic-nonepileptic-seizures-a-nonrandomized-controlled-study
#16
Amanda Cristian Serafim de Barros, Ana Eliza Romano Furlan, Lucia Helena Neves Marques, Gerardo Maria de Araújo Filho
PURPOSE: Psychogenic nonepileptic seizures (PNES) are paroxysmal episodes superficially resembling epileptic seizures but are not associated with any electrical abnormalities. Despite the existence of recent evidence addressing psychological interventions on PNES, there is a scarcity of studies investigating such interventions on patients with dual diagnoses, such as in temporal lobe epilepsy/mesial temporal sclerosis (TLE-MTS) with comorbid PNES; TLE-MTS is a very frequent epilepsy syndrome found in tertiary centers...
March 27, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29588989/psychogenic-non-epileptic-seizures-among-patients-with-functional-neurological-disorder-a-case-series-from-a-tanzanian-referral-hospital-and-literature-review
#17
Marieke C J Dekker, Sarah J Urasa, Marissa Kellogg, William P Howlett
Objective: Functional neurological disorders (FNDs) and psychogenic nonepileptic seizures (PNES) are likely as common in Sub-Saharan Africa (SSA) as in the rest of the world, but there is a dearth of literature on the epidemiology and clinical presentation of these disorders in Africa. The purpose of this paper is to describe a case series of FNDs presenting to a referral hospital in SSA. In addition, we review the existing literature on FNDs in Africa. Methods: A hospital-based retrospective cross-sectional study was conducted to determine the prevalence, epidemiology, and clinical phenotype of FNDs and PNES in a referral hospital in Northern Tanzania over a 6-year period (2007-2013)...
March 2018: Epilepsia Open
https://www.readbyqxmd.com/read/29588977/simultaneous-occurrence-of-nonepileptic-and-epileptic-seizures-during-a-single-period-of-in-patient-video-electroencephalographic-monitoring
#18
Hany El-Naggar, Patrick Moloney, Peter Widdess-Walsh, Ronan Kilbride, Norman Delanty, Gerard Mullins
Epilepsy and psychogenic nonepileptic seizures (PNES) can coexist and may present in two forms: sequential and simultaneous. In sequential presentations, epileptic seizures (ES) are treated and PNES emerge later. Simultaneous recording of ES and PNES by video-electroencephalogram (vEEG) is less well described. We retrospectively reviewed all patients diagnosed with PNES by vEEG following standard seizure induction practices over a 21-month period. Within this cohort, we established the prevalence of coexisting epilepsy using clinical and electrographic data acquired from our epilepsy-specific patient record...
December 2017: Epilepsia Open
https://www.readbyqxmd.com/read/29588959/pnes-around-the-world-where-we-are-now-and-how-we-can-close-the-diagnosis-and-treatment-gaps-an-ilae-pnes-task-force-report
#19
Kousuke Kanemoto, W Curt LaFrance, Roderick Duncan, David Gigineishvili, Sung-Pa Park, Yukari Tadokoro, Hiroko Ikeda, Ravi Paul, Dong Zhou, Go Taniguchi, Mike Kerr, Tomohiro Oshima, Kazutaka Jin, Markus Reuber
An international consensus clinical practice statement issued in 2011 ranked psychogenic nonepileptic seizures (PNES) among the top three neuropsychiatric problems. An ILAE PNES Task Force was founded and initially charged with summarizing the current state of the art in terms of diagnosis and treatment, resulting in two publications. The first described different levels of diagnostic certainty. The second summarized current knowledge of management approaches. The present paper summarizes an international workshop of the ILAE PNES Task Force that focused on the current understanding and management of PNES around the world...
September 2017: Epilepsia Open
https://www.readbyqxmd.com/read/29574898/the-frequency-and-management-of-seizures-during-psychological-treatment-among-patients-with-psychogenic-nonepileptic-seizures-and-epilepsy
#20
Steven Kemp, Christopher D Graham, Rebecca Chan, Hayley Kitchingman, Kirsty Vickerman, Markus Reuber
OBJECTIVE: Growing evidence suggests that psychological treatments are effective for improving outcomes in both epilepsy and psychogenic nonepileptic seizures (PNES). However, the risk of in-session seizures may cause concerns about safety and about seizures disrupting treatment. This study explores the risk of in-session seizures in patients with epilepsy and those with PNES, the timings of seizures during psychological therapy, and the responses of therapists to seizures. METHODS: Consecutive patients with epilepsy or PNES attending 2 neurology centers in the United Kingdom for psychological treatment to help with their seizure disorders were studied...
March 25, 2018: Epilepsia
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