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https://www.readbyqxmd.com/read/28436567/an-ultrastructural-study-of-chondroptosis-programmed-cell-death-in-degenerative-intervertebral-discs-in%C3%A2-vivo
#1
Li-Bo Jiang, Hai-Xiao Liu, Yu-Long Zhou, Sun-Ren Sheng, Hua-Zi Xu, En-Xing Xue
Apoptosis has been regarded to mediate intervertebral disc degeneration (IDD); however, the basic question of how the apoptotic bodies are cleared in the avascular intervertebral disc without phagocytes, which are essential to apoptosis, remains to be elucidated. Our goals were to investigate the ultrastructure of nucleus pulposus (NP) cells undergoing chondroptosis, a variant of apoptotic cell death, in a rabbit annular needle-puncture model of IDD. Experimental IDD was induced by puncturing discs with a 16-G needle in New Zealand rabbits...
April 24, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28435926/lumbar-disc-herniation-presenting-with-contralateral-symptoms-a-case-report
#2
Zhi Sheng Darren Koh, Shuxun Lin, Hwee Weng Dennis Hey
Lumbar disc herniation is common and may be symptomatic. The magnetic resonance imaging (MRI) scan is an appropriate tool to confirm the diagnosis and affected level of the spine. While a disc herniation is usually associated with ipsilateral symptoms, a few cases have been reported to present with contralateral symptoms. We report a unique case of left lumbar disc herniation at L5/S1 who presented with contralateral symptoms and was successfully treated with a right L5/S1 foraminal block. However, the patient developed concordant ipsilateral symptoms 6 weeks later and was treated with left L5/S1 microdiscectomy...
March 2017: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/28435916/feasibility-of-endoscopic-discectomy-by-inter-laminar-approach-at-a-high-volume-tertiary-public-hospital-in-a-developing-country
#3
Shardul Madhav Soman, Jayprakash Vrajlal Modi, Jimmy Chokshi
BACKGROUND: Surgical treatment for lumbar disc herniation consists of discectomy performed either open or minimally invasive techniques. Endoscopic discectomy using the tubular retractor is been increasingly used as it gives advantage of smaller incision, less tissue injury and faster recovery. The aim of this study was to check its feasibility and learning curve at a tertiary public sector hospital with a large volume load (more than 50 spine surgeries per month) with treatment provided free of cost...
March 2017: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/28431955/the-course-of-modic-vertebral-body-changes-after-posterolateral-lumbar-fusion-on-fused-and-adjacent-levels-a-systematic-review-of-the-literature
#4
REVIEW
Stella Taylor Portella, Marcus André Acioly
According to the original description by Modic et al., the natural course of bone marrow signal abnormalities is an inexorable, progressive one, however recent evidence has demonstrated in healthy individuals and those suffering from lumbar disc herniation that the course of endplate degenerative changes is rather dynamic and sometimes regressive. The evolution of such changes in lumbar fused segments and adjacent levels is largely unknown. The literature relevant to the course of Modic changes on fused and adjacent levels, as well as its clinical correspondence in patients undergoing posterolateral lumbar fusion was collected...
April 18, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28430050/letter-to-the-editor-risk-of-recurrence-of-lumbar-disc-herniation-after-microdiscectomy-for-scoliosis
#5
Zhiming Tu, Yawei Li, Lei Li, Guohua Lv, Bing Wang
No abstract text is available yet for this article.
April 21, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28429143/how-to-treat-lumbar-disc-herniation-in-pregnancy-a-systematic-review-on-current-standards
#6
REVIEW
Alberto Di Martino, Fabrizio Russo, Luca Denaro, Vincenzo Denaro
PURPOSE: In this systematic review, we aim to illustrate the current and safe concepts in the assessment, diagnosis and management of herniated lumbar disc (HLD) during pregnancy. METHODS: A systematic review and reporting on the diagnosis, treatment and clinical results of HLD during pregnancy is performed. RESULTS: The MRI represents the first level and safest diagnostic tool for pregnant women affected by spinal problems allowing for a noninvasive and detailed radiological examination of the spine...
April 20, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28428080/the-effect-of-preoperative-lumbar-epidural-corticosteroid-injection-on-post-operative-infection-rate-in-patients-undergoing-single-level-lumbar-decompression
#7
Jonathan G Seavey, George C Balazs, Theodore Steelman, Melvin Helgeson, David E Gwinn, Scott C Wagner
BACKGROUND CONTEXT: Lumbar epidural corticosteroid injections (LECI) are frequently used in the treatment of lumbar intervertebral disc herniation with radiculopathy and lumbar spinal stenosis. Although widely utilized, their effect on the outcomes and complications of subsequent surgery is unclear. Post-operative infection can be a morbid complication following spine surgery, and recent literature has suggested that the risk may be increased in patients undergoing lumbar spinal surgery who had previously received LECI...
April 17, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28427393/correlation-between-intervertebral-disc-degeneration-paraspinal-muscle-atrophy-and-lumbar-facet-joints-degeneration-in-patients-with-lumbar-disc-herniation
#8
Dong Sun, Peng Liu, Jie Cheng, Zikun Ma, Jingpei Liu, Tingzheng Qin
BACKGROUND: To assess the correlation between lumbar disc degeneration (LDD), multifidus muscle atrophy (LMA), and facet joints degeneration in patients with L4-L5 lumbar disc herniation (LDH). METHODS: Sixty patients with L4-L5 LDH diagnosed by a 1.5 T MRI scanner were enrolled in the study group and another 60 patients with non-specific back pain were enrolled in the control group. LDD, LMA, and facet joints degeneration were examined and analyzed independently by two independent orthopedic surgeons using T2-weighted images...
April 20, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28424918/risk-factors-for-surgical-site-infections-among-1-772-patients-operated-on-for-lumbar-disc-herniation-a-multicentre-observational-registry-based-study
#9
Samer Habiba, Øystein P Nygaard, Jens I Brox, Christian Hellum, Ivar M Austevoll, Tore K Solberg
BACKGROUND: There are no previous studies evaluating risk factors for surgical site infections (SSIs) and the effectiveness of prophylactic antibiotic treatment (PAT), specifically for patients operated on for lumbar disc herniation. METHOD: This observational multicentre study comprises a cohort of 1,772 consecutive patients operated on for lumbar disc herniation without laminectomy or fusion at 23 different surgical units in Norway. The patients were interviewed about SSIs according to a standardised questionnaire at 3 months' follow-up...
April 20, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28424050/in-the-quest-for-degenerative-lumbar-spinal-stenosis-etiology-the-schmorl-s-nodes-model
#10
Janan Abbas, Viviane Slon, Dan Stein, Natan Peled, Israel Hershkovitz, Kamal Hamoud
BACKGROUND: Degenerative lumbar spinal stenosis (DLSS) is a common health problem in the elderly and usually associated with three-joint complex degeneration. Schmorl's nodes (SNs) are described as vertical herniation of the disc into the vertebral body through a weakened part of the end plate that can lead to disc degeneration. Since SNs can harm the spine unit stability, the association between DLSS and SNs is expected. The aim of this study is to shed light on the relationship between degenerative lumbar spinal stenosis and SNs...
April 20, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28423437/-expert-assessment-of-traumatic-disc-herniations
#11
Martin Schwarze, Marc-André Weber, Florin M Bucur, Marcus Schiltenwolf
In numerous legal areas, expert assessments are needed to clarify the causality of herniated discs: Was the damage caused by an accident? The literature mentions specific requirements regarding the trauma mechanism as well as temporal criteria, which prescribe the causality test. These are essentially high-energy traumas with immediate functional impairments. Accident-related MRI examinations are of paramount importance in the expert assessment process to confirm the primary body harm. In examining the causality constituting liability, competitive causes must be assessed...
April 19, 2017: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/28423044/the-long-term-outcome-of-micturition-defecation-and-sexual-function-after-spinal-surgery-for-cauda-equina-syndrome
#12
Nina S Korse, Anna B Veldman, Wilco C Peul, Carmen L A Vleggeert-Lankamp
BACKGROUND: Cauda equina syndrome (CES) is a rare neurologic complication of lumbar herniated disc for which emergency surgical decompression should be undertaken. Despite the common belief that the restoration of functions that are affected by CES can take several years postoperatively, follow up seldom exceeds the first year after surgery. Long term outcome of especially micturition, defecation and sexual function-which are by definition affected in CES-are unknown. The aim of this study is to evaluate 1) postoperative long term outcome of micturition, defecation and sexual function in CES patients 2) attitude of patients towards received hospital care with regard to (recovery of) these functions...
2017: PloS One
https://www.readbyqxmd.com/read/28422798/anterior-versus-posterior-thoracic-discectomy-a-systematic-review
#13
Eoghan T Hurley, Andrew B Maye, Marcus Timlin, Frank G Lyons
STUDY DESIGN: Systematic literature review OBJECTIVE.: To systematically review the current evidence in the literature on thoracic discectomies, to compare the clinical outcomes and to determine whether there is evidence to support the use of either the anterior or posterior approach. SUMMARY OF BACKGROUND DATA: Thoracic disc herniations often present with myelopathy, radiculopathy or a combination of both. The posterior approach for thoracic discectomy has been associated with a lower complication rate, but no systematic exists comparing the clinical outcomes...
April 18, 2017: Spine
https://www.readbyqxmd.com/read/28413533/persistent-l5-lumbosacral-radiculopathy-caused-by-lumbosacral-trunk-schwannoma
#14
Guive Sharifi, Amin Jahanbakhshi
Schwannomais, usually, benign tumor of nerve sheath that occurs evenly along the spinal cord. Intra-pelvic schwannoma is very rare entity that may arise from lumbosacral nerve roots or from sciatic nerve. Radicular pain of the lower limb as a presenting symptom of pelvic schwannoma is extremely rare. In the current report, the patient is presented with a right sided L5 radicular pain typical of lumbar discopathy. Interestingly, a herniated lumbar disc was noted on lumbosacral magnetic resonance imaging (MRI)...
January 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/28399828/discography-aids-definitive-diagnosis-of-posterior-epidural-migration-of-lumbar-disc-fragments-case-report-and-literature-review
#15
Morito Takano, Tomohiro Hikata, Soraya Nishimura, Michihiro Kamata
BACKGROUND: Posterior epidural migration of lumbar disc fragments (PEMLDF) is extremely rare. It is often confused with other posterior lesions and is usually diagnosed intraoperatively. We here describe the use of preoperative discography in the diagnosis of PEMLDF. CASE PRESENTATION: A 78-year-old man presented with acute low back pain, gait disturbance, and paresthesia in both legs. Magnetic resonance imaging showed a mass located posteriorly and laterally to the left aspect of the dural sac at the L3 level...
April 11, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28392347/predictors-of-improvement-in-low-back-pain-after-lumbar-decompression-surgery-prospective-study-of-140-patients
#16
Hiroki Oba, Jun Takahashi, Takahiro Tsutsumimoto, Shota Ikegami, Hiroshi Ohta, Mutsuki Yui, Hidemi Kosaku, Takayuki Kamanaka, Hiromichi Misawa, Hiroyuki Kato
BACKGROUND: Lumbar decompression surgery is often used to treat neurological symptoms of the lower extremity as a result of lumbar disease. However, this method also leads to the improvement of the accompanying low back pain (LBP). We studied the extent of LBP improvement after lumbar decompression surgery without fusion and the associated preoperative factors. METHODS: Patients (n = 140) with lumbar spinal stenosis (n = 90) or lumbar disc herniation (n = 50) were included...
April 6, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28391024/endoscopic-intralaminar-approach-for-the-treatment-of-lumbar-disc-herniation
#17
Joachim M Oertel, Benedikt W Burkhardt
BACKGROUND: Almost every surgical approach carries the risk to cause some degree of spinal instability, especially in case of excessive resection of the lamina and facet joint. This study describes the endoscopic intralaminar approach (ILA) for the treatment of cranially and caudally migrated lumbar disc herniation. METHODS: Thirty-one patients who underwent endoscopic ILA for 26 caudally and 5 cranially migrated lumbar disc herniation were identified from a prospectively database...
April 5, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28387658/do-turkish-patients-with-lumbar-disc-herniation-know-body-mechanics
#18
Sacide Yildizeli Topcu
BACKGROUND AND OBJECTIVE: Most common and important cause of the low back pain is lumbar disc herniation. Patients with lumbar disc herniation face with difficulties during daily activities due to the reduction of physical functions. In order to maintain daily activities without pain and discomfort, the patients should be informed about proper positions and body mechanics. The aim of the study was to determine the knowledge and the applications of the patients with lumbar disc herniation about body mechanics...
March 31, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28385420/less-is-more-efficacy-of-rapid-3d-t2-space-in-ed-patients-with-acute-atypical-low-back-pain
#19
Nicholas A Koontz, Richard H Wiggins, Megan K Mills, Michael S McLaughlin, Elaine C Pigman, Yoshimi Anzai, Lubdha M Shah
RATIONALE AND OBJECTIVES: Emergency department (ED) patients with acute low back pain (LBP) may present with ambiguous clinical findings that pose diagnostic challenges to exclude cauda equina syndrome (CES). As a proof of concept, we aimed to determine the efficacy of a rapid lumbar spine (LS) magnetic resonance imaging (MRI) screening protocol consisting of a single 3D-T2 SPACE FS (3D-T2 Sampling Perfection with Application optimized Contrasts using different flip angle Evolution fat saturated) sequence relative to conventional LS MRI to exclude emergently treatable pathologies in this complex patient population...
April 3, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28384266/static-axial-overloading-primes-lumbar-caprine-intervertebral-discs-for-posterior-herniation
#20
Cornelis P L Paul, Magda de Graaf, Arno Bisschop, Roderick M Holewijn, Peter M van de Ven, Barend J van Royen, Margriet G Mullender, Theodoor H Smit, Marco N Helder
INTRODUCTION: Lumbar hernias occur mostly in the posterolateral region of IVDs and mechanical loading is an important risk factor. Studies show that dynamic and static overloading affect the nucleus and annulus of the IVD differently. We hypothesize there is also variance in the effect of overloading on the IVD's anterior, lateral and posterior annulus, which could explain the predilection of herniations in the posterolateral region. We assessed the regional mechanical and cellular responses of lumbar caprine discs to dynamic and static overloading...
2017: PloS One
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