keyword
https://read.qxmd.com/read/38017756/target-and-cantilever-supported-seawater-velocity-sensor-based-on-panda-fiber-polarization-interferometer
#21
JOURNAL ARTICLE
Yu Li, Shanshan Wang, Lijun Yu, Jing Wang
It is necessary to develop a novel optical low velocity sensor for seawater. In this paper, a fiber optic seawater velocity sensor based on a target cantilever reflective polarization interferometer is presented theoretically and experimentally. Height: width of equal strength cantilever is determined by finite element method as 22:5, and the seawater velocity sensing experiment is carried out using this parameter. The sensitivity obtained by experiment is consistent with the theory, whose correlation coefficient is 0...
October 23, 2023: Optics Express
https://read.qxmd.com/read/38016693/modern-photodynamic-glioblastoma-therapy-using-curcumin-or-parietin-loaded-lipid-nanoparticles-in-a-cam-model-study
#22
JOURNAL ARTICLE
Jan Schulze, Lisa Schöne, Abdallah M Ayoub, Damiano Librizzi, Muhammad Umair Amin, Konrad Engelhardt, Behrooz H Yousefi, Lena Bender, Jens Schaefer, Eduard Preis, Michaela Schulz-Siegmund, Christian Wölk, Udo Bakowsky
Natural photosensitizers, such as curcumin or parietin, play a vital role in photodynamic therapy (PDT), causing a light-mediated reaction that kills cancer cells. PDT is a promising treatment option for glioblastoma, especially when combined with nanoscale drug delivery systems. The curcumin- or parietin-loaded lipid nanoparticles were prepared via dual asymmetric centrifugation and subsequently characterized through physicochemical analyses including dynamic light scattering, laser Doppler velocimetry, and atomic force microscopy...
November 28, 2023: ACS Applied Bio Materials
https://read.qxmd.com/read/37970925/characterization-of-the-normal-fetal-circulatory-system-of-the-ductus-venosus-using-sound-complexity-parameters
#23
JOURNAL ARTICLE
A S R Souza, C F Carvalho, G F A Souza, R B Moraes
The aim of this study was to characterize the normality of the fetal circulatory system through the time between ventricular systoles of the ductus venosus in the three gestational trimesters in healthy fetuses using nonlinear methods of the complexity of the signal. A prospective cohort study was conducted at the Instituto de Medicina Integral Prof. Fernando Figueira (IMIP) from December 2019 to May 2020. Pregnant women between 11 and 14 weeks, with intrauterine pregnancy and healthy fetus were included. Patients with multiple gestation, positive screening for congenital malformation, including heart disease, and under 18 years of age were excluded...
2023: Brazilian Journal of Medical and Biological Research
https://read.qxmd.com/read/37896505/laser-velocimetry-for-the-in-situ-sensing-of-deep-sea-hydrothermal-flow-velocity
#24
JOURNAL ARTICLE
Jingjing Sun, Lei Zhang, Guojie Tu, Shenglai Zhen, Zhigang Cao, Guosheng Zhang, Benli Yu
Laser Doppler velocimetry (LDV) based on a differential laser Doppler system has been widely used in fluid mechanics to measure particle velocity. However, the two outgoing lights must intersect strictly at the measurement position. In cross-interface applications, due to interface effects, two beams of light become easily disjointed. To address the issue, we present a laser velocimeter in a coaxial arrangement consisting of the following components: a single-frequency laser (wavelength λ = 532 nm) and a Twyman-Green interferometer...
October 12, 2023: Sensors
https://read.qxmd.com/read/37831823/precision-doppler-shift-measurements-with-a-frequency-comb-calibrated-laser-heterodyne-radiometer
#25
JOURNAL ARTICLE
Ryan K Cole, Connor Fredrick, Newton H Nguyen, Scott A Diddams
We report precision atmospheric spectroscopy of CO2 using a laser heterodyne radiometer (LHR) calibrated with an optical frequency comb. Using the comb calibrated LHR, we record spectra of atmospheric CO2 near 1572.33 nm with a spectral resolution of 200 MHz, using sunlight as a light source. The measured CO2 spectra exhibit frequency shifts by approximately 11 MHz over the course of the 5-h measurement, and we show that these shifts are caused by Doppler effects due to wind along the spectrometer line of sight...
October 15, 2023: Optics Letters
https://read.qxmd.com/read/37817001/laboratory-performance-testing-of-aqueous-nasal-inhalation-products-for-droplet-particle-size-distribution-an-assessment-from-the-international-pharmaceutical-aerosol-consortium-on-regulation-and-science-ipac-rs
#26
JOURNAL ARTICLE
William H Doub, Julie M Suman, Mark Copley, Adrian P Goodey, Sana Hosseini, Jolyon P Mitchell
Although nasal inhalation products are becoming more and more important for the delivery of medicines, characterization of these products for quality control and assessment of bioequivalence is complicated. Most of the problems encountered are associated with the assessment of aerodynamic droplet/particle size distribution (APSD). The droplets produced by the various nasal devices are large, and for suspension products, individual droplets may contain multiple drug particles or none at all. Assessment of suspension products is further complicated by the presence of solid excipient particles...
October 10, 2023: AAPS PharmSciTech
https://read.qxmd.com/read/37796291/a-century-of-exercise-physiology-concepts-that-ignited-the-study-of-human-thermoregulation-part-2-physiological-measurements
#27
REVIEW
Sean R Notley, Duncan Mitchell, Nigel A S Taylor
In this, the second of four historical reviews on human thermoregulation during exercise, we examine the research techniques developed by our forebears. We emphasise calorimetry and thermometry, and measurements of vasomotor and sudomotor function. Since its first human use (1899), direct calorimetry has provided the foundation for modern respirometric methods for quantifying metabolic rate, and remains the most precise index of whole-body heat exchange and storage. Its alternative, biophysical modelling, relies upon many, often dubious assumptions...
October 5, 2023: European Journal of Applied Physiology
https://read.qxmd.com/read/37783552/ultra-fast-ultrasound-blood-flow-velocimetry-for-carotid-artery-with-deep-learning
#28
JOURNAL ARTICLE
Bingbing He, Jian Lei, Xun Lang, Zhiyao Li, Wang Cui, Yufeng Zhang
Accurate measurement of blood flow velocity is important for the prevention and early diagnosis of atherosclerosis. However, due to the uncertainty of parameter settings, the autocorrelation velocimetry methods based on clutter filtering are prone to incorrectly filter out the near-wall blood flow signal, resulting in poor velocimetric accuracy. In addition, the Doppler coherent compounding acts as a low-pass filter, which also leads to low values of blood flow velocity estimated by the above methods. Motivated by this status quo, here we propose a deep learning estimator that combines clutter filtering and blood flow velocimetry based on the adaptive property of one-dimensional convolutional neural network (1DCNN)...
October 2023: Artificial Intelligence in Medicine
https://read.qxmd.com/read/37778280/is-a-sflt-1-plgf-cutoff-of-38-suitable-to-predict-adverse-outcomes-in-pregnancies-with-abnormal-uterine-artery-doppler-velocimetry-in-the-second-trimester
#29
JOURNAL ARTICLE
Sara Caamiña Álvarez, Alicia Rodríguez Zurita, Tania Del Carmen De Ganzo Suárez, José Fernando De Luis Escudero, Nieves Sierra Medina, Carolina Chulilla Pérez, Cecilia Martín Fernández de Basoa, José Luis Trabado Montesino, María Teresa Concepción Masip, Miguel Ángel García Bello
OBJECTIVE: To determine the optimal cutoff value for the soluble fms-like tyrosine kinase-1 (sFlt-1)/placental growth factor (PlGF) ratio to predict maternal and fetal adverse events in pregnancies with uterine artery Doppler scans results above the 95th percentile in the late second trimester. STUDY DESIGN: Retrospective, observational cohort study on 116 asyntomatic patients with abnormal uterine artery Doppler scans at gestational week 25. The sFlt-1/PlGF ratio was determined within the weeks 25 to 29 of gestation and ROC curve analysis performed...
December 2023: Pregnancy Hypertension
https://read.qxmd.com/read/37761391/the-current-role-of-the-sflt-1-plgf-ratio-and-the-uterine-umbilical-cerebral-doppler-ultrasound-in-predicting-and-monitoring-hypertensive-disorders-of-pregnancy-an-update-with-a-review-of-the-literature
#30
REVIEW
Cristian Nicolae Chirilă, Claudiu Mărginean, Paula Maria Chirilă, Mirela Liana Gliga
Regarding the hypertensive disorders of pregnancy, pre-eclampsia (PE) remains one of the leading causes of severe and life-threatening maternal and fetal complications. Screening of early-onset PE (<34 weeks of pregnancy), as well as late-onset PE (≥34 weeks), shows poor performance if based solely on clinical features. In recent years, biochemical markers from maternal blood-the pro-angiogenic protein placental growth factor (PlGF) and the antiangiogenic protein soluble FMS-like tyrosine kinase 1 (sFlt-1)-and Doppler velocimetry indices-primarily the mean uterine pulsatility index (PI), but also the uterine resistivity index (RI), the uterine systolic/diastolic ratio (S/D), uterine and umbilical peak systolic velocity (PSV), end-diastolic velocity (EDV), and uterine notching-have all shown improved screening performance...
August 22, 2023: Children
https://read.qxmd.com/read/37759790/mechanism-of-anti-salmonella-rabbit-immunoglobulin-adsorption-on-polymer-particles
#31
JOURNAL ARTICLE
Paulina Żeliszewska, Monika Wasilewska, Jolanta Szych, Zbigniew Adamczyk
The adsorption of anti-Salmonella rabbit immunoglobulin (IgaR) on negatively charged polymer particles leading to the formation of immunolatex was studied using various techniques comprising atomic force microscopy (AFM) and laser Doppler velocimetry (LDV). Initially, the basic physicochemical properties of IgaR molecules and the particles, inter alia their electrophoretic mobilities, the zeta potentials and hydrodynamic diameters, were determined under different ionic strengths and pHs. Applying AFM, single immunoglobulin molecules adsorbed on mica were also imaged, which allowed to determine their size...
September 15, 2023: Biomolecules
https://read.qxmd.com/read/37728683/assessment-of-systemic-circulation-using-ultrasound-doppler-in-late-onset-neonatal-sepsis-and-its-clinical-correlation-an-observational-study
#32
JOURNAL ARTICLE
Pari Singh, Arjun Verma, Nandini Malshe, Aditya Kallimath, Gauri Oak, Manoj Malviya, Nitin Chouthai, Pradeep Suryawanshi
OBJECTIVES: To measure the Doppler velocimetry parameters in the anterior cerebral artery (ACA), superior mesenteric artery (SMA), and main renal artery (RA) in neonates with late-onset sepsis and correlate it with associated clinical morbidities. METHODOLOGY: Prospective observational study carried out at a tertiary-level neonatal intensive care unit in India in 2022, enrolling 20 neonates with late-onset neonatal sepsis (LONS). Baseline characteristics and sepsis parameters obtained...
September 20, 2023: Journal of Ultrasound
https://read.qxmd.com/read/37718558/prediction-of-labour-outcomes-using-prelabour-computerised-cardiotocogram-and-maternal-and-fetal-doppler-indices-a%C3%A2-prospective-cohort-study
#33
JOURNAL ARTICLE
Sakita Moungmaithong, Michelle Sung Nga Lam, Angel Hoi Wan Kwan, Sani Tsz Kei Wong, Ada Wing Ting Tse, Daljit Singh Sahota, Sin Ting Angela Tai, Liona Chiu Yee Poon
OBJECTIVES: To investigate the association and the potential value of prelabour fetal heart rate short-term variability (STV) determined by computerised cardiotocography (cCTG) and maternal and fetal Doppler in predicting labour outcomes. DESIGN: Prospective cohort study. SETTING: The Prince of Wales Hospital, a tertiary maternity unit, in Hong Kong SAR. POPULATION: Women with a term singleton pregnancy in latent phase of labour or before labour induction were recruited during May 2019-November 2021...
September 17, 2023: BJOG: An International Journal of Obstetrics and Gynaecology
https://read.qxmd.com/read/37712421/maternal-plgf-and-umbilical-dopplers-predict-pregnancy-outcomes-at-diagnosis-of-early-onset-fetal-growth-restriction
#34
JOURNAL ARTICLE
Rebecca Spencer, Kasia Maksym, Kurt Hecher, Karel Maršál, Francesc Figueras, Gareth Ambler, Harry Whitwell, Nuno Rocha Nené, Neil J Sebire, Stefan R Hansson, Anke Diemert, Jana Brodszki, Eduard Gratacós, Yuval Ginsberg, Tal Weissbach, Donald M Peebles, Ian Zachary, Neil Marlow, Angela Huertas-Ceballos, Anna L David
BACKGROUNDSevere, early-onset fetal growth restriction (FGR) causes significant fetal and neonatal mortality and morbidity. Predicting the outcome of affected pregnancies at the time of diagnosis is difficult, thus preventing accurate patient counseling. We investigated the use of maternal serum protein and ultrasound measurements at diagnosis to predict fetal or neonatal death and 3 secondary outcomes: fetal death or delivery at or before 28+0 weeks, development of abnormal umbilical artery (UmA) Doppler velocimetry, and slow fetal growth...
September 15, 2023: Journal of Clinical Investigation
https://read.qxmd.com/read/37550172/role-of-advanced-hemodynamic-ultrasound-evaluation-in-the-differential-diagnosis-of-middle-cerebral-artery-stenosis-introducing-morphological-criteria
#35
JOURNAL ARTICLE
Giovanni Malferrari, Nicola Merli, Vincenzo Inchingolo, Antonio Siniscalchi, Domenico Laterza, Daniela Monaco, Giorgia Arnone, Andrea Zini, Francesco Prada, Cristiano Azzini, Maura Pugliatti
OBJECTIVE: The aim of the work described here was to determine the possible impact of the new technique advanced hemodynamic ultrasound evaluation (AHUSE) in identification of severe intracranial stenosis. Transcranial Doppler (TCD) and transcranial color-coded Doppler (TCCD) provide reliable velocimetric data, the indirect analysis of which allows us to obtain information on the patency of vessels and assumed stenosis range. However, very tight stenoses (>95%) cannot be detected with velocimetric criteria because of spectrum drops and the absence of high velocities, so that the right curve of the Spencer equation cannot be solved...
August 5, 2023: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/37544409/do-differences-in-diagnostic-criteria-for-late-fetal-growth-restriction-matter
#36
JOURNAL ARTICLE
Bronacha Mylrea-Foley, Raffaele Napolitano, Sanne Gordijn, Hans Wolf, Christoph C Lees, Tamara Stampalija
BACKGROUND: Criteria for diagnosis of fetal growth restriction differ widely according to national and international guidelines, and further heterogeneity arises from the use of different biometric and Doppler reference charts, making the diagnosis of fetal growth restriction highly variable. OBJECTIVE: This study aimed to compare fetal growth restriction definitions between Delphi consensus and Society for Maternal-Fetal Medicine definitions, using different standards/charts for fetal biometry and different reference ranges for Doppler velocimetry parameters...
November 2023: American journal of obstetrics & gynecology MFM
https://read.qxmd.com/read/37539161/movement-characteristics-of-the-inclined-surface-flow-of-the-open-channel-on-the-nanoscale-surface
#37
JOURNAL ARTICLE
Yen-Chang Chen, Han-Chung Yang
This study investigates the water flow characteristics on a solid surface with nanoscale compared to a normal solid surface. The experiment uses a high-speed video system and Fiber-optic Laser Doppler Velocimetry to measure the flow condition of the droplet and velocity distribution profile in the inclined surface flow of the open channel, respectively. The results showed that the movement speed of water droplets on the nanoscale surface was about 2 times faster than on the normal surface. The mean error of each velocity profile was 0...
July 2023: Heliyon
https://read.qxmd.com/read/37496642/reference-values-for-ductus-venosus-doppler-velocity-indices-between-11-and-13-6-weeks-of-gestation-a-single-center-prospective-study-in-iran
#38
JOURNAL ARTICLE
Somayeh Hajiahmadi, Alireza Rezaei Adariani, Ehsan Amini, Sina Rasti
BACKGROUND: This study aimed to investigate reference Doppler velocimetry indices (DVIs) of the fetal ductus venosus (DV) during 11-13 + 6 gestational weeks. MATERIALS AND METHODS: In a prospective observation over referrals to a single tertiary care center in a 2-year interval, normal singleton pregnancies with fetal crown-rump lengths (CRLs) of 43-80 mm were examined by a single experienced sonographer for their DV pulsatility index (DVPI), DV resistance index (DVRI), and S-wave maximum velocity/A-wave minimum velocity (S/A ratio)...
2023: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://read.qxmd.com/read/37475362/tamper-performance-for-confined-laser-drive-applications
#39
JOURNAL ARTICLE
Sonny Ly, Janghyuk Lee, Alexander M Rubenchik, Jonathan C Crowhurst, Charles D Boley, Vanessa N Peters, Wesley J Keller
The shock imparted by a laser beam striking a metal surface can be increased by the presence of an optically transparent tamper plate bonded to the surface. We explore the shock produced in an aluminum slab, for a selection of tamper materials and drive conditions. The experiments are conducted with a single-pulse laser of maximum fluence up to 100 J/cm2 . The pressure and impulse are measured by photon doppler velocimetry, while plasma imaging is used to provide evidence of nonlinear tamper absorption. We demonstrate a pressure enhancement of 50x using simple commercially available optics...
July 3, 2023: Optics Express
https://read.qxmd.com/read/37448172/management-of-large-placental-chorioangiomas-novel-approach-for-fetal-intervention
#40
JOURNAL ARTICLE
N Agarwal, R Papanna, E P Bergh, E Hernandez-Andrade, S Backley, A Salazar, A Johnson, J Espinoza
OBJECTIVE: There is a paucity in the literature regarding evidence-based guidelines for the management of large placental chorioangiomas (≥ 4cm diameter). The objective of this study is to describe different thermal techniques that may improve the efficiency of in utero intervention for chorioangiomas. METHODS: This is a retrospective cohort study of 34 patients referred for the management of large placental chorioangiomas in a single center from January 2011 to December 2022, who were managed expectantly or with intervention...
July 13, 2023: Ultrasound in Obstetrics & Gynecology
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