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Transcranial doppler

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https://www.readbyqxmd.com/read/29677060/cerebral-small-vessel-but-not-large-vessel-disease-is-associated-with-impaired-cerebral-autoregulation-during-cardiopulmonary-bypass-a-retrospective-cohort-study
#1
Yohei Nomura, Roland Faegle, Daijiro Hori, Abbas Al-Qamari, Alexander J Nemeth, Rebecca Gottesman, Gayane Yenokyan, Charles Brown, Charles W Hogue
BACKGROUND: Impaired cerebral blood flow (CBF) autoregulation during cardiopulmonary bypass (CPB) is associated with stroke and other adverse outcomes. Large and small arterial stenosis is prevalent in patients undergoing cardiac surgery. We hypothesize that large and/or small vessel cerebral arterial disease is associated with impaired cerebral autoregulation during CPB. METHODS: A retrospective cohort analysis of data from 346 patients undergoing cardiac surgery with CPB enrolled in an ongoing prospectively randomized clinical trial of autoregulation monitoring were evaluated...
April 17, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29675634/investigation-of-circle-of-willis-variants-and-hemodynamic-parameters-in-twins-using-transcranial-color-coded-doppler-sonography
#2
Bianka Forgó, Ádám Domonkos Tárnoki, Dávid László Tárnoki, Levente Littvay, Corrado Fagnani, Maria Antonietta Stazi, Giorgio Meneghetti, Emanuela Medda, Filippo Farina, Claudio Baracchini
Morphological and hemodynamic variations of the circle of Willis (CW) may have an important impact on cerebrovascular events. However, the environmental and genetic influence remains unclear. For this reason we studied the variations and hemodynamic parameters of the CW in twins using transcranial color-coded sonography (TCCS). Sixty-four twins, 19 monozygotic (MZ) and 13 dizygotic (DZ) pairs from the Italian Twin Registry (average age 45.0 ± 13.7 years) underwent TCCS and risk factor assessment. We examined CW morphology and recorded peak systolic velocity (PSV), end-diastolic velocity (EDV) and pulsatility index (PI)...
April 19, 2018: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29674994/a-cross-sectional-study-on-cerebral-hemodynamics-after-mild-traumatic-brain-injury-in-a-pediatric-population
#3
Corey M Thibeault, Samuel Thorpe, Michael J O'Brien, Nicolas Canac, Mina Ranjbaran, Ilyas Patanam, Artin Sarraf, James LeVangie, Fabien Scalzo, Seth J Wilk, Ramon Diaz-Arrastia, Robert B Hamilton
The microvasculature is prominently affected by traumatic brain injury (TBI), including mild TBI (concussion). Assessment of cerebral hemodynamics shows promise as biomarkers of TBI, and may help inform development of therapies aimed at promoting neurologic recovery. The objective of this study was to assess the evolution in cerebral hemodynamics observable with transcranial Doppler (TCD) ultrasound in subjects suffering from a concussion at different intervals during recovery. Pediatric subjects between the ages of 14 and 19 years clinically diagnosed with a concussion were observed at different points post-injury...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29670392/cerebral-blood-flow-velocity-in-migraine-and-chronic-tension-type-headache-patients
#4
S Karacay Ozkalayci, B Nazliel, H Z Batur Caglayan, C Irkec
Introduction: The present study seeks to use transcranial Doppler ultrasound to evaluate cerebral blood flow velocities in anterior and posterior circulation arteries, during an attack-free episode in migraine patients, with and without aura, as well as in chronic tension-type headache patients who were not receiving prophylactic medication. Methods: A total of 50 patients (35 female, 15 male) were evaluated during a headache-free episode: 30 migraine patients without aura (mean age: 32±8 years), 10 migraine patients with aura (mean age: 34±4 years), and 10 patients with chronic tension-type headache (mean age: 34±5 years)...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/29668544/splenectomy-to-optimize-hemoglobin-s-control-in-children-with-sickle-cell-anemia-on-chronic-transfusion-therapy-for-stroke-prevention
#5
L Vandy Black, Jolie S Ramesar, Catherine H Boston
Chronic transfusion therapy with the goal of maintaining a hemoglobin (Hb) S <30% is the primary recommended treatment for children with sickle cell anemia and a history of overt stroke or abnormal transcranial Doppler examination. We report chronic hypersplenism as a cause of poor HbS% control in 3 children on chronic transfusion therapy for stroke prevention. Splenectomy resulted in a 39.77% (95% confidence interval, 34.3-45.3, P<0.0001) mean reduction in HbS% with no perioperative or infectious complications suggesting the need for additional research into splenectomy as a therapeutic option for select high-risk children to optimize transfusion therapy for stroke prevention...
April 17, 2018: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/29663853/collateral-pial-circulation-relates-to-the-degree-of-brain-edema-on-ct-24-hours-after-ischemic-stroke
#6
Orlando Galego, Joana Jesus-Ribeiro, Mariana Baptista, João Sargento-Freitas, Ana Inês Martins, Fernando Silva, Gustavo Cordeiro Santos, Luís Cunha, César Nunes, Egídio Machado
Background Cerebral edema is frequent in patients with acute ischemic stroke (AIS) who undergo reperfusion therapy and is associated with high mortality. The impact of collateral pial circulation (CPC) status on the development of edema has not yet been determined. Methods We studied consecutive patients with AIS and documented M1-middle cerebral artery (MCA) and/or distal internal carotid artery (ICA) occlusion who underwent reperfusion treatment. Edema was graded on the 24-hour non-contrast computed tomography (NCCT) scan...
January 1, 2018: Neuroradiology Journal
https://www.readbyqxmd.com/read/29660362/variability-in-cerebral-blood-flow-velocity-at-rest-and-during-mental-stress-in-healthy-individuals-associations-with-cardiovascular-parameters-and-cognitive-performance
#7
Casandra I Montoro, Stefan Duschek, Gustavo A Reyes Del Paso
This study analyzed variability in cerebral blood flow velocity (CBFV) and possible underlying physiological mechanisms during rest and a mental arithmetic task. Blood flow velocities were bilaterally recorded by transcranial Doppler sonography in the anterior and middle cerebral arteries of 43 participants. Electrocardiography, continuous blood pressure (BP) and respiratory recordings were additionally obtained. Fast Fourier transformation revealed a spectral profile with two main components in CBFV, one in the very low frequency (VLF, 0...
April 13, 2018: Biological Psychology
https://www.readbyqxmd.com/read/29659999/increased-body-mass-index-associated-with-reduced-risk-of-delayed-cerebral-ischemia-and-subsequent-infarction-after-aneurysmal-subarachnoid-hemorrhage
#8
Lorenzo Rinaldo, Alejandro A Rabinstein, Giuseppe Lanzino
BACKGROUND: Increased body mass index (BMI) may be protective against cerebral ischemia in certain clinical contexts. OBJECTIVE: To investigate whether increased BMI was associated with delayed cerebral ischemia (DCI) and subsequent infarction after aneurysmal subarachnoid hemorrhage (aSAH). METHODS: We retrospectively reviewed the clinical course of patients presenting to our institution for management of aSAH. Patient were segregated according to BMI< or ≥29...
April 4, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29652541/dynamic-cerebral-autoregulation-is-impaired-during-sub-maximal-isometric-handgrip-in-patients-with-heart-failure
#9
Juliana R Caldas, Ronney B Panerai, Angela S M Salinet, Edson Bor-Seng-Shu, Filomena R B G Galas, Graziela S R Ferreira, Ligia Camara, Rogerio Hora Passos, Juliano P Almeida, Ricardo C Nogueira, Marcelo de Lima Oliveira M, Thompson G Robinson, Ludhmila A Hajjar
BACKGROUND: The incidence of neurological complications, including stroke and cognitive dysfunction is elevated in heart failure (HF) patients with reduced ejection fraction. We hypothesized that the cerebrovascular response to isometric handgrip (iHG) is altered in HF patients. METHODS: Adults with HF and healthy volunteers were included. Cerebral blood velocity (CBV, transcranial Doppler, middle cerebral artery) and arterial blood pressure (BP, Finometer) were continuously recorded supine for 6 minutes, corresponding to one min baseline, three min of iHG exercise, at 30% maximum voluntary contraction, followed by two min of recovery...
April 13, 2018: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/29649509/cybersickness-related-changes-in-brain-hemodynamics-a-pilot-study-comparing-transcranial-doppler-and-near-infrared-spectroscopy-assessments-during-a-virtual-ride-on-a-roller-coaster
#10
Alireza Mazloumi Gavgani, Rachel H X Wong, Peter R C Howe, Deborah M Hodgson, Frederick R Walker, Eugene Nalivaiko
Our aim was to assess cerebral blood flow changes during cybersickness. Transcranial Doppler (TCD) ultrasound and near infrared spectroscopy (NIRS) were used separately in two independent experiments. In both studies, a 15-min virtual roller coaster ride was used as a provocative visual stimulus. Subjective nausea ratings were obtained at 1 min intervals. The TCD study was performed in 14 healthy subjects (8 males and 6 females); in this study we also measured heart rate and arterial pressure. In a separate study a 52-channel NIRS device (Hitachi ETG-4000) was used to monitor activated brain regions by measuring oxy-hemoglobin (HbO2) concentration in 9 healthy subjects (4 male, 5 females)...
April 9, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29644151/trans-cranial-doppler-as-an-ancillary-study-supporting-irreversible-brain-injury-in-a-post-cardiac-arrest-patient-on-extracorporeal-membrane-oxygenation
#11
Naresh Mullaguri, Aarti Sarwal, Nakul Katyal, Premkumar Nattanamai, Pravin George, Christopher R Newey
Obtaining neuroimaging in patients on cardiopulmonary support devices such as extracorporeal membrane oxygenation (ECMO) can be challenging, given the complexities in monitoring, instrumentation, and associated hemodynamic lability. Transcranial Doppler (TCD) is used as an ancillary test for the assessment of cerebral circulatory arrest, but its use in non-pulsatile blood flow in venoarterial (VA) ECMO is not well described. We report the use of TCD in a patient on VA ECMO post-cardiac arrest for evaluation of death by neurological criteria...
February 6, 2018: Curēus
https://www.readbyqxmd.com/read/29619647/assessment-of-cerebral-hemodynamic-parameters-using-pulsatile-versus-non-pulsatile-cerebral-blood-outflow-models
#12
Agnieszka Uryga, Magdalena Kasprowicz, Leanne Calviello, Rolf R Diehl, Katarzyna Kaczmarska, Marek Czosnyka
BACKGROUND: Prior methods evaluating the changes in cerebral arterial blood volume (∆Ca BV) assumed that brain blood transport distal to big cerebral arteries can be approximated with a non-pulsatile flow (CFF) model. In this study, a modified ∆Ca BV calculation that accounts for pulsatile blood flow forward (PFF) from large cerebral arteries to resistive arterioles was investigated. The aim was to assess cerebral hemodynamic indices estimated by both CFF and PFF models while changing arterial blood carbon dioxide concentration (EtCO2 ) in healthy volunteers...
April 4, 2018: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/29601112/cerebral-perfusion-characteristics-show-differences-in-younger-versus-older-children-with-sickle-cell-anaemia-results-from-a-multiple-inflow-time-arterial-spin-labelling-study
#13
Jamie M Kawadler, Patrick W Hales, Simon Barker, Timothy C S Cox, Fenella J Kirkham, Chris A Clark
Sickle cell anaemia (SCA) is associated with chronic anaemia and oxygen desaturation, which elevate cerebral blood flow (CBF) and increase the risk of neurocognitive complications. Arterial spin labelling (ASL) provides a methodology for measuring CBF non-invasively; however, ASL techniques using only a single inflow time are not sufficient to fully characterize abnormal haemodynamic behaviour in SCA. This study investigated haemodynamic parameters from a multi-inflow-time ASL acquisition in younger (8-12 years) and older (13-18 years) children with SCA with and without silent cerebral infarction (SCI+/-) (n = 20 and 19 respectively, 6 and 4 SCI+ respectively) and healthy controls (n = 9 and 7 respectively)...
March 30, 2018: NMR in Biomedicine
https://www.readbyqxmd.com/read/29600896/wavelet-decomposition-analysis-is-a-clinically-relevant-strategy-to-evaluate-cerebrovascular-buffering-of-blood-pressure-after-spinal-cord-injury
#14
Saqib Saleem, Diana Vucina, Zoe Sarafis, Amanda H X Lee, Jordan W Squair, Otto F Barak, Geoff B Coombs, Tanja Mijacika, Andrei V Krassioukov, Philip N Ainslie, Zeljko Dujic, Yu-Chieh Tzeng, Aaron A Phillips
The capacity of cerebrovasculature to buffer changes in blood pressure (BP) is crucial to prevent stroke, the incidence of which is 3-4 fold elevated after spinal cord injury (SCI). Disruption of descending sympathetic pathways within the spinal cord due to cervical SCI may result in impaired cerebrovascular buffering. Only linear analyses of cerebrovascular buffering of BP, such as transfer function, have been utilized in SCI research. This approach does not account for inherent non-linearity and non-stationarity components of cerebrovascular regulation, often depends on perturbations of BP to increase the statistical power, and does not account for influence of arterial CO2 tension...
March 30, 2018: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/29595639/an-overlooked-cause-in-a-patient-with-recurrent-ischemic-stroke-a-case-report
#15
Xunzhe Yang, Mingsheng Liu, Yicheng Zhu, Xiaobo Zhang, Shan Gao, Jun Ni
RATIONALE: The majority of ischemic strokes are due to cardioembolism, large vessel atherothromboembolism, small vessel occlusive disease, or other unusual mechanisms. In most clinical settings, many strokes without a well-defined etiology requires a thorough diagnostic evaluation, otherwise the underlying cause might be easily overlooked. Here we report on the rare cause of a patient with recurrent stroke. PATIENT CONCERNS: A 50-year-old female patient had a 4-year history of recurrent acute onset of neurological deficits...
March 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29593024/feasibility-of-improving-cerebral-autoregulation-in-acute-intracerebral-haemorrhage-breathe-ich-study-a-protocol-for-an-experimental-interventional-study
#16
Jatinder S Minhas, Ronney B Panerai, Thompson G Robinson
INTRODUCTION: Cerebral autoregulation (CA) is impaired in a multitude of neurological conditions. Increasingly, clinical studies are correlating the nature of this impairment with prognostic markers. In acute intracerebral haemorrhage (ICH), impairment of CA has been associated with worsening clinical outcomes including poorer Glasgow Coma Score and larger haematoma volume. Hypocapnia has been shown to improve CA despite concerns over hypoperfusion and consequent ischaemic risks, and it is therefore hypothesised that hypocapnia (via hyperventilation) in acute ICH may improve CA and consequently clinical outcome...
March 27, 2018: BMJ Open
https://www.readbyqxmd.com/read/29579816/systodiastolic-separation-expresses-cerebral-circulatory-arrest
#17
A Cacciatori, M Godino, R Mizraji
There is a situation before the cerebral circulatory cessation phase, the systodiastolic separation in transcranial Doppler (TCD), which may raise doubts to the operator technician who performs it. A total of 266 studies were performed in 188 neurocritical patients over a 9-year period: 88 cases (77%) corresponded to cerebral circulatory arrest (CCA) which accompanies brain death (BD); 9 (5%) presented the systodiastolic separation pattern. In 1 of those 9 there was persistence of cough reflex and spontaneous breathing; in 5, CCA was not reached; only 3 evolved to CCA...
March 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29579815/utility-of-transcranial-doppler-in-the-coordination-of-transplants-10-years-of-experience
#18
A Cacciatori, M Godino, R Mizraji
Transcranial Doppler (TCD) integrated to multimodal neuromonitoring of neurocritical patients is a useful tool in the clinical follow-up. A retrospective and descriptive study of 194 patients who were admitted into the intensive care unit (ICU) was carried out from December 2007 to February 2017. We analyzed the distribution of study frequencies with respect to the pathologies that motivated them, the characteristics of patients who evolved to brain death (BD), and most frequent patterns of cerebral circulatory arrest...
March 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29575406/knee-high-compression-socks-minimize-head-up-tilt-induced-cerebral-and-cardiovascular-responses-following-dynamic-exercise
#19
Tristan W Dorey, Myles W O'Brien, Susan A Robinson, Derek S Kimmerly
INTRODUCTION: In healthy individuals during a non-exercised state, knee-high compression socks (CS) may reduce the magnitude of lower limb venous pooling during orthostasis but are not effective at minimizing the incidence of presyncopal symptoms. However, exaggerated reductions in cerebral blood flow velocity (CBV), and cardiac stroke volume (SV) occur during passive head-up tilt (HUT) testing following dynamic exercise. It is unknown if CS can minimize post-exercise HUT-induced decrements in CBV and SV in this population...
March 25, 2018: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29571928/hemodynamic-changes-during-rewarming-phase-of-whole-body-hypothermia-therapy-in-neonates-with-hypoxic-ischemic-encephalopathy
#20
Tai-Wei Wu, Benita Tamrazi, Sadaf Soleymani, Istvan Seri, Shahab Noori
OBJECTIVE: To delineate the systemic and cerebral hemodynamic response to incremental increases in core temperature during the rewarming phase of therapeutic hypothermia in neonatal hypoxic-ischemic encephalopathy (HIE). STUDY DESIGN: Continuous hemodynamic data, including heart rate (HR), mean arterial blood pressure (MBP), cardiac output by electrical velocimetry (COEV ), arterial oxygen saturation, and renal (RrSO2 ) and cerebral (CrSO2 ) regional tissue oxygen saturation, were collected from 4 hours before the start of rewarming to 1 hour after the completion of rewarming...
March 20, 2018: Journal of Pediatrics
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