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Transcranial doppler

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https://www.readbyqxmd.com/read/29219028/ambulatory-pulse-pressure-brain-neuronal-fiber-integrity-and-cerebral-blood-flow-in-older-adults
#1
Takashi Tarumi, Binu P Thomas, Ciwen Wang, Li Zhang, Jie Liu, Marcel Turner, Jonathan Riley, Nikita Tangella, Kyle B Womack, Diana R Kerwin, C Munro Cullum, Hanzhang Lu, Wanpen Vongpatanasin, David C Zhu, Rong Zhang
Ambulatory blood pressure (ABP) reflects the end-organ vascular stress in daily life; however, its influence on brain neuronal fiber integrity and cerebral blood flow (CBF) remains unclear. The objective of this study was to determine the associations among ABP, white matter (WM) neuronal fiber integrity, and CBF in older adults. We tested 144 participants via ABP monitoring and diffusion tensor imaging. The total level and pulsatile indices of CBF were measured by phase-contrast MRI and transcranial Doppler, respectively...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/29212807/the-independent-and-interactive-effects-of-incremental-heat-strain-orthostatic-stress-and-mild-hypohydration-on-cerebral-perfusion
#2
Rebekah A I Lucas, Luke C Wilson, Philip N Ainslie, Jui-Lin Fan, Kate N Thomas, James D Cotter
The purpose of this study was to identify the dose-dependent effects of heat strain and orthostasis (via lower-body negative pressure; LBNP), with and without mild hypohydration, on systemic function and cerebral perfusion. Eleven males (Mean ±SD: 27 ±7 y; body mass 77 ±6 kg), resting supine in a water-perfused suit, underwent progressive passive heating [0.5°C increments in core temperature (Tc, oesophageal to +2.0°C)] whilst euhydrated (EUH) or hypohydrated (HYPO, 1.5-2% body mass deficit). At each thermal state, mean cerebral artery blood velocity (MCAvmean, Transcranial Doppler), partial pressure of end-tidal carbon dioxide (PETCO2), heart rate (HR) and mean arterial blood pressure (MAP, photoplethysmography) were measured continuously during LBNP (0, -15, -30, -45 mm Hg)...
December 6, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/29201539/assessment-of-cerebral-blood-flow-with-magnetic-resonance-imaging-in-children-with-sickle-cell-disease-a-quantitative-comparison-with-transcranial-doppler-ultrasonography
#3
Paula L Croal, Jackie Leung, Przemyslaw Kosinski, Manohar Shroff, Isaac Odame, Andrea Kassner
Introduction: Transcranial Doppler ultrasonography (TCD) is a clinical tool for stratifying ischemic stroke risk by identifying abnormal elevations in blood flow velocity (BFV) in the middle cerebral artery (MCA). However, TCD is not effective at screening for subtle neurologic injury such as silent cerebral infarcts. To better understand this disparity, we compared TCD measures of BFV with tissue-level cerebral blood flow (CBF) using arterial spin-labeling MRI in children with and without sickle cell disease, and correlated these measurements against clinical hematologic measures of disease severity...
November 2017: Brain and Behavior
https://www.readbyqxmd.com/read/29195161/prenatal-and-pubertal-testosterone-affect-brain-lateralization
#4
T Beking, R H Geuze, M van Faassen, I P Kema, B P C Kreukels, T G G Groothuis
After decades of research, the influence of prenatal testosterone on brain lateralization is still elusive, whereas the influence of pubertal testosterone on functional brain lateralization has not been investigated, although there is increasing evidence that testosterone affects the brain in puberty. We performed a longitudinal study, investigating the relationship between prenatal testosterone concentrations in amniotic fluid, pubertal testosterone concentrations in saliva, and brain lateralization (measured with functional Transcranial Doppler ultrasonography (fTCD)) of the Mental Rotation, Chimeric Faces and Word Generation tasks...
November 6, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29195085/clinical-and-hematological-profile-in-a-newborn-cohort-with-hemoglobin-sc
#5
Paulo V Rezende, Millane V Santos, Gustavo F Campos, Laura L M Vieira, Maristela B Souza, André R Belisário, Celia M Silva, Marcos B Viana
OBJECTIVES: Hemoglobin SC is the second most common variant of sickle-cell disease worldwide, after hemoglobin SS. The objectives of the study were to describe the clinical and laboratory characteristics of hemoglobin SC disease in children from a newborn screening program and treated at a blood donor center. METHODOLOGY: This study assessed a cohort of 461 infants born between 01/01/1999 and 12/31/2012 and followed-up until 12/31/2014. Clinical events were expressed as rates for 100 patient-years, with 95% confidence intervals...
November 28, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/29191539/prognostic-role-of-microembolic-signals-after-endovascular-treatment-in-anterior-circulation-ischemic-stroke-patients
#6
Filippo Farina, Anna Palmieri, Silvia Favaretto, Federica Viaro, Giacomo Cester, Francesco Causin, Claudio Baracchini
BACKGROUND: Endovascular treatment (EVT) is an effective therapy for acute ischemic stroke due to large artery occlusion (LAO) of the anterior circulation. Yet, some patients do not experience clinical improvement regardless of successful recanalization and reperfusion. The reasons are unknown but one possible explanation is micro-vessel obstruction downstream. OBJECTIVES: To assess the presence of microembolic signals (MES) with transcranial Doppler (TCD), and define their role as predictors of clinical outcome in EVT-treated stroke patients...
November 27, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29191476/the-association-between-serum-uric-acid-and-asymptomatic-intracranial-arterial-stenosis-in-middle-aged-koreans
#7
J K Ahn, J Hwang, J H Hwang, W T Yoon, P W Chung, S Ryu
BACKGROUND AND AIMS: Intracranial arterial stenosis (ICAS) is one of the most common causes of stroke, especially in Asians. Hyperuricemia has been associated with an increased risk of comorbidities such as metabolic syndrome or cardiovascular diseases. However, there are few studies focusing on the association between serum uric acid (SUA) levels and asymptomatic ICAS. The aim of this study was to explore the association between SUA and the prevalence of ICAS in middle-aged Korean health screening examinees...
October 27, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29191325/percutaneous-closure-of-patent-foramen-ovale-in-patients-with-migraine-the-premium-trial
#8
RANDOMIZED CONTROLLED TRIAL
Jonathan M Tobis, Andrew Charles, Stephen D Silberstein, Sherman Sorensen, Brijeshwar Maini, Phillip A Horwitz, John C Gurley
BACKGROUND: Migraine is a prevalent and disabling disorder. Patent foramen ovale (PFO) has been associated with migraine, but its role in the disorder remains poorly understood. OBJECTIVES: This study examined the efficacy of percutaneous PFO closure as a therapy for migraine with or without aura. METHODS: The PREMIUM (Prospective, Randomized Investigation to Evaluate Incidence of Headache Reduction in Subjects With Migraine and PFO Using the AMPLATZER PFO Occluder to Medical Management) was a double-blind study investigating migraine characteristics over 1 year in subjects randomized to medical therapy with a sham procedure (right heart catheterization) versus medical therapy and PFO closure with the Amplatzer PFO Occluder device (St...
December 5, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29190150/intravenous-saline-administration-in-patients-with-severe-acquired-brain-injury-and-orthostatic-intolerance-for-tilt-table-mobilization
#9
Christian Riberholt, Niels Olesen, Peter Hovind, Jesper Mehlsen, Tue Hvass Petersen
PRIMARY OBJECTIVE: This study aimed to investigate the effect of intravenous saline administration on orthostatic hypotension (OH) during head up tilt (HUT) and the change in the renin-angiotensin-aldosterone system before and after HUT in patients with severe acquired brain injury (ABI). RESEARCH DESIGN: The study is designed as an observational study. METHODS AND PROCEDURES: Fourteen patients with ABI, low level of consciousness and OH were monitored before, during and after HUT with non-invasive beat-to-beat blood pressure measurement, and transcranial Doppler determination of middle cerebral artery blood flow velocity...
November 30, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29189269/comparison-of-transcranial-doppler-and-ultrasound-tagged-near-infrared-spectroscopy-for-measuring-relative-changes-in-cerebral-blood-flow-in-human-subjects
#10
Michael S Lipnick, Elizabeth A Cahill, John R Feiner, Philip E Bickler
BACKGROUND: Currently, no reliable method exists for continuous, noninvasive measurements of absolute cerebral blood flow (CBF). We sought to determine how changes measured by ultrasound-tagged near-infrared spectroscopy (UT-NIRS) compare with changes in CBF as measured by transcranial Doppler (TCD) in healthy volunteers during profound hypocapnia and hypercapnia. METHODS: Ten healthy volunteers were monitored with a combination of TCD, UT-NIRS (c-FLOW, Ornim Medical), as well as heart rate, blood pressure, end-tidal PCO2 (PEtCO2), end-tidal O2, and inspired O2...
November 14, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29188396/cerebrovascular-hemodynamics-during-the-practice-of-bhramari-pranayama-kapalbhati-and-bahir-kumbhaka-an-exploratory-study
#11
L Nivethitha, A Mooventhan, N K Manjunath, Lokesh Bathala, Vijay K Sharma
Various pranayama techniques are known to produce different physiological effects. We evaluated the effect of three-different pranayama techniques on cerebrovascular hemodynamics. Eighteen healthy volunteers with the mean ± standard deviation age of 23.78 ± 2.96 years were performed three-different pranayama techniques: (1) Bhramari, (2) Kapalbhati and (3) Bahir-Kumbhaka in three-different orders. Continuous transcranial Doppler (TCD) monitoring was performed before, during and after the pranayama techniques...
November 29, 2017: Applied Psychophysiology and Biofeedback
https://www.readbyqxmd.com/read/29187557/the-assessment-of-neurovascular-coupling-with-the-addenbrooke-s-cognitive-examination-a-functional-transcranial-doppler-ultrasonographic-study
#12
Lucy C Beishon, Claire A L Williams, Ronney B Panerai, Thompson G Robinson, Victoria Joanna Haunton
Cerebrovascular dysfunction occurs early in dementia and can be identified by Transcranial Doppler ultrasonography (TCD). Few studies have examined cerebral blood flow velocity (CBFv) responses to a detailed cognitive battery. This study aimed to characterise all CBFv responses, and the effect of hemispheric dominance, to the Addenbrooke's Cognitive Examination (ACE-III) in healthy volunteers. Forty volunteers underwent continuous bilateral TCD, beat-to-beat blood pressure (MAP) (Finapres), heart rate (HR) (electrocardiogram), and end-tidal CO2 (ETCO2) (capnography) monitoring...
November 29, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/29182378/early-changes-in-cerebral-autoregulation-among-youth-hospitalized-after-sports-related-traumatic-brain-injury
#13
Monica S Vavilala, Carly K Farr, Arraya Watanitanon, Bs Crystalyn Clark-Bell, Theerada Chandee, Anne Moore, William Armstead
OBJECTIVE: To examine early cerebral haemodynamic changes among youth hospitalized with sports-related traumatic brain injury (TBI). STUDY DESIGN: Youth 0-18 years admitted to a level one trauma centre with sports-related TBI were enrolled. Daily measures included clinical symptoms and Glasgow Coma Scale (GCS) score. Using Transcranial Doppler (TCD) ultrasonography and tilt testing, we measured middle cerebral artery flow velocity (Vmca) and cerebral autoregulation index (ARI)...
November 28, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29163346/paroxysmal-symptoms-as-the-first-manifestation-of-multiple-sclerosis-mimicking-a-transient-ischemic-attack-a-report-of-two-cases
#14
Yao Zhang, Siyuan Fan, Fei Han, Yan Xu
Paroxysmal symptoms are unusual manifestations of multiple sclerosis (MS). When presented as the first clinical manifestation, paroxysmal symptoms may easily be mistaken for transient ischemic attack (TIA). Previously, several cases of MS that reported with paroxysmal symptoms were misdiagnosed as TIA. Here, we report two additional cases, focusing on the clinical characteristics of paroxysmal symptoms in MS. Both cases had paroxysmal symptoms as their first manifestation; one presented with transient dizziness, left face numbness, and right limb weakness, and the other presented with episodic lightheadedness, blurred vision, nausea, palpitations, and tremulousness upon standing...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29158187/white-matter-structural-integrity-and-trans-cranial-doppler-blood-flow-pulsatility-in-normal-aging
#15
Roman Fleysher, Michael L Lipton, Olga Noskin, Tatjana Rundek, Richard Lipton, Carol A Derby
Cerebrovascular diseases underlie many forms of age-related cognitive impairment and the mechanism linking the two is hypothesized to involve adverse changes in white matter (WM) integrity. Despite being systemic, small vessel disease does not uniformly affect WM. We performed voxel-wise analysis of MRI images to examine the association between fractional anisotropy (FA) - a diffusion tensor measure of WM structural integrity - and pulsatility index (PI) - a transcranial Doppler ultrasound measure of abnormal arterial flow - in adults over the age of 70 years who were free of stroke and dementia...
November 17, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/29157167/%C3%AE-s-globin-gene-haplotype-and-the-stroke-risk-among-egyptian-children-with-sickle-cell-disease
#16
Heba H Abou-Elew, Ilham Youssry, Shireen Hefny, Rania H Hashem, Nevine Fouad, Rania A Zayed
BACKGROUND AND AIM OF WORK: Sickle cell disease (SCD) is an inherited disease of the beta globin gene. The βS globin gene haplotypes are Senegal, Benin, Bantu, Cameroon, Arab-Indian and atypical haplotypes. In SCD, stroke is a life-threatening event in both adults and children. In light of paucity of studies on βS globin gene haplotypes in Egypt, we aimed to determine βS globin gene haplotypes in children with SCD and study their impact on stroke risk. METHODS: Fifty-two SCD patients were included in the study, they were 26 males and 26 females with age range from 3 to 18 years old...
November 20, 2017: Hematology (Amsterdam, Netherlands)
https://www.readbyqxmd.com/read/29137102/lateral-medullary-infarction-with-similar-features-of-brown-sequard-syndrome-caused-by-vertebrobasilar-dysplasia-and-klippel-feil-syndrome-a-case-report
#17
Jingzhe Han, Duanhua Cao, Guomei Ma, Tingting Wang, Ye Ji, Zhilei Kang
RATIONALE: Patients with Klippel-Feil syndrome (KFS) are always anomaly associated with vertebrobasilar dysplasia. That may present commonly as infarction of brainstem, medulla, and cerebellum. In this article, we reported a rare case of lateral medullary infarction (LMI) with similar features of Brown Sequard syndrome caused by vertebrobasilar dysplasia and KFS, and the 2 rare conditions that are causally related. The case is being reported because of its unusual and rare presentation...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29135481/role-and-limitations-of-transcranial-doppler-and-brain-death-of-patients-on-veno-arterial-extracorporeal-membrane-oxygenation
#18
Mino Cestari, André L N Gobatto, Mauricio Hoshino
No abstract text is available yet for this article.
November 8, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/29131095/intracranial-internal-carotid-artery-wall-calcification-in-ischemic-strokes-treated-with-thrombolysis
#19
Miguel Tábuas-Pereira, João Sargento-Freitas, Fernando Silva, Joana Parra, Patrícia Mendes, Vera Seara, Miguel Mesquita, Mariana Baptista, Gustavo Cordeiro, Luis Cunha
BACKGROUND: Calcifications are an important element of atherosclerotic plaques and have been used as a marker of atherosclerosis and clinical outcome predictor in different vascular territories. CT-scan, performed in the acute ischemic stroke setting, can reliably detect intracranial arterial calcifications. OBJECTIVES: To investigate the association between intracranial internal carotid artery calcification and functional outcome, symptomatic intracerebral hemorrhage (sICH), recanalization, and death...
November 13, 2017: European Neurology
https://www.readbyqxmd.com/read/29130477/transcranial-doppler-and-lower-extremity-function-in-older-adults-einstein-aging-study
#20
Ali Ezzati, Tatjana Rundek, Joe Verghese, Carol A Derby
OBJECTIVES: To determine whether transcranial Doppler ultrasound (TCD) measures of mean blood flow velocity (MBFV) in the major cerebral arteries are associated with measures of lower extremity function in community-dwelling older adults. DESIGN: Cross-sectional study. SETTING: Community sample. PARTICIPANTS: Individuals aged 70 and older (mean 79.5, 54% female) without dementia participating in the Einstein Aging Study (N = 200)...
November 11, 2017: Journal of the American Geriatrics Society
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