keyword
MENU ▼
Read by QxMD icon Read
search

Enhancers

keyword
https://www.readbyqxmd.com/read/28934789/lack-of-gender-and-age-differences-in-pain-measurements-following-exercise-in-people-with-chronic-whiplash-associated-disorders
#1
Kelly Ickmans, Anneleen Malfliet, Margot De Kooning, Lisa Goudman, Ives Hubloue, Tom Schmitz, Dorien Goubert, Maria Encarnacion Aguilar-Ferrandiz
BACKGROUND: Individuals with chronic whiplash associated disorders (WAD) present persistent pain in the absence of structural pathology. In these people, altered central pain processing and central sensitization are observed. The role of personal factors, such as gender and age, on pain processing mechanisms in chronic WAD, however, is still unclear. OBJECTIVES: This study investigated possible gender- and age-related differences in self-reported and experimental pain measurements in people with chronic WAD...
September 2017: Pain Physician
https://www.readbyqxmd.com/read/28934754/cntn-1-enhances-chemoresistance-in-human-lung-adenocarcinoma-through-induction-of-epithelial-mesenchymal-transition-by-targeting-the-pi3k-akt-pathway
#2
Ruijie Zhang, Shenghua Sun, Fuyun Ji, Chun Liu, Hua Lin, Lihua Xie, Honghui Yang, Wenxiang Tang, Yan Zhou, Jianping Xu, Pei Li
BACKGROUND/AIMS: Chemoresistance has been a major obstacle to the effective treatment of lung cancer. Previously, we found that contactin-1 (CNTN-1) is related to cisplatin resistance in lung adenocarcinoma. Here, we aimed to investigate the underlying mechanism behind the role of CNTN-1 in cisplatin resistance in lung adenocarcinoma. METHODS: EMT-associated phenotypes, including alterations in cellular morphology and marker (E-cadherin, N-cadherin and Vimentin) expression, were compared between A549 cells and A549/DDP cells (a cisplatin-resistant cell line of lung adenocarcinoma with abnormal CNTN-1 expression) by using real-time time PCR and Western blotting...
September 1, 2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/28934724/integrating-health-into-local-climate-response-lessons-from-the-u-s-cdc-climate-ready-states-and-cities-initiative
#3
Mary C Sheehan, Mary A Fox, Charlotte Kaye, Beth Resnick
Public health has potential to serve as a frame to convey the urgency of behavior change needed to adapt to a changing climate and reduce greenhouse gas emissions. Local governments form the backbone of climate-related public health preparedness. Yet local health agencies are often inadequately prepared and poorly integrated into climate change assessments and plans. We reviewed the climate health profiles of 16 states and two cities participating in the U.S. Centers for Disease Control and Prevention (CDC)'s Climate-Ready States and Cities Initiative (CRSCI) that aims to build local capacity to assess and respond to the health impacts of climate change...
September 20, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28934717/expression-of-c-ebp%C3%AE-in-myeloid-progenitors-during-sepsis-promotes-immunosuppression
#4
Jun Dai, Ajinkya Kumbhare, Dima Youssef, Zhi Q Yao, Charles E McCall, Mohamed El Gazzar
Sepsis-induced myeloid-derived suppressor cells (MDSCs) contribute to immunosuppression associated with sepsis. We reported that the CCAAT enhancer-binding protein C/EBPβ activates microRNA (miR)-21 and miR-181b expressions, which induce transcription factor NFI-A to support the generation and expansion of MDSCs in the bone marrow and spleens of septic mice. Here, using a conditional knockout mouse model lacking C/EBPβ in the myeloid lineage, we find that without C/EBPβ, myeloid progenitor cells could not express miR-21 or miR-181b, and ectopic expression of C/EBPβ in the C/EBPβ-deficient myeloid progenitors activated the expression of the two miRNAs...
September 18, 2017: Molecular Immunology
https://www.readbyqxmd.com/read/28934688/fulvic-acid-anchored-layered-double-hydroxides-a-multifunctional-composite-adsorbent-for-the-removal-of-anionic-dye-and-toxic-metal
#5
Lei Li, Guangxia Qi, Bangda Wang, Dongbei Yue, Yi Wang, Tsutomu Sato
A novel multifunctional composite adsorbent which possesses the ability for anion exchange and toxic metal complexation has been synthesized by the hybridization of layered double hydroxides (LDH) and fulvic acid (FA) in this study. The results show that FA with lots of functional groups can be effectively and stably anchored on the surface of LDH through coagulation process without occupying the interlayer of LDH. Therefore, the anion exchange ability remains and the adsorption capacity of Orange II can reach 1...
September 6, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28934687/the-role-of-thiocyanate-in-enhancing-the-process-of-sulfite-reducing-cr-vi-by-inhibiting-the-formation-of-reactive-oxygen-species
#6
Bo Jiang, Shuaishuai Xin, Yijie Liu, Haihong He, Lin Li, Yizhen Tang, Siyi Luo, Xuejun Bi
The reductive detoxification of Cr(VI) by sulfite is known as the prevailing strategy and can be successfully implemented for the treatment of Cr(VI)-contaminated waters. However, this method inevitably faces the challenges of excessive consumption of sulfite due to the generations of highly oxidative OH and SO4(-) during the process of sulfite reducing Cr(VI). In this study, we find that a small quantity of thiocyanate (SCN) can catalytically enhance the process efficiency of Cr(VI) reduction by sulfite and effectively prevent the excessive consumption of sulfite...
September 12, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28934664/targeted-h-triggered-bubble-generating-nanosystems-for-effective-therapy-in-cancer-cells
#7
Zhili Deng, Menghuan Tang, Li Zhao, Yijuan Long, Zuhuang Wen, Yuan Cheng, Huzhi Zheng
A novel targeting drug delivery system for cancer therapy based on H(+)-triggered bubble-generating nanosystems (BGNSs) was engineered. First, hollow mesoporous silica nanoparticles (HMSNs) were used to load doxorubicin (DOX). Then, the obtained drug-loaded HMSNs were treated with NaHCO3 to prepare the BGNSs. The BGNSs were coated with polydopamine (pDA), and finally, folic acids (FA) were anchored on the nanosystems to obtain the desired nanoscale drug delivery system (BGNSs@pDA-FA). BGNSs@pDA-FA was effectively internalized by cancer cells through folate receptor-mediated endocytosis and generated CO2 bubbles under the acidic environment of the lysosomes, thus enhancing lysosomal membrane permeability (LMP) to release caspase-3 into the cytoplasm, resulting in cancer cell death via an apoptosis-like pathway...
September 14, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28934662/a-pc-pu-nanoparticle-pu-decellularized-scaffold-composite-vascular-patch-synergistically-optimized-overall-performance-promotes-endothelialization
#8
Jun Zhang, Cheng Liu, Fuling Feng, Dawei Wang, Shuaishuai Lu, Guo Wei, Hong Mo, Tong Qiao
Composite vascular patches have gained increasingly attention due to the limited availability of autologous patches (vascular graft materials made from the blood vessels of the same recipient), the lack of growth capability of nonautologous patches (vascular graft materials made from the blood vessels of a different donor) and the disadvantages of synthetic patches. In this study, we report a highly biocompatible phosphatidylcholine-polyurethane nanoparticle/polyurethane/decellularized scaffold composite vascular patch (PCVP)...
September 6, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28934658/changes-in-activation-energy-and-kinetics-of-heat-activated-persulfate-oxidation-of-phenol-in-response-to-changes-in-ph-and-temperature
#9
Jie Ma, Haiyan Li, Liping Chi, Hongkun Chen, Changzhao Chen
Persulfate (peroxydisulfate, S2O8(2-)) is the newest oxidant used for the in situ chemical oxidation (ISCO) remediation of soil and groundwater. The present study investigated impacts of solution pH, temperature, and persulfate concentration on the reaction rate constant (k1), activation energy (Ea), and reaction order of the heat-activated persulfate process. Phenol was chosen as the model organic contaminant. As temperature increased from 30 °C to 70 °C, k1 exhibited a significant increase from 0.003 h(-1)∼0...
September 13, 2017: Chemosphere
https://www.readbyqxmd.com/read/28934653/mixed-sulfate-reducing-bacteria-enriched-microbial-fuel-cells-for-the-treatment-of-wastewater-containing-copper
#10
Waheed Miran, Jiseon Jang, Mohsin Nawaz, Asif Shahzad, Sang Eun Jeong, Che Ok Jeon, Dae Sung Lee
Microbial fuel cells (MFCs) have been widely investigated for organic-based waste/substrate conversion to electricity. However, toxic compounds such as heavy metals are ubiquitous in organic waste and wastewater. In this work, a sulfate reducing bacteria (SRB)-enriched anode is used to study the impact of Cu(2+) on MFC performance. This study demonstrates that MFC performance is slightly enhanced at concentrations of up to 20 mg/L of Cu(2+), owing to the stimulating effect of metals on biological reactions...
September 13, 2017: Chemosphere
https://www.readbyqxmd.com/read/28934651/persulfate-enhanced-photocatalytic-degradation-of-bisphenol-a-by-g-c3n4-nanosheets-under-visible-light-irradiation
#11
Bochuan Liu, Meng Qiao, Yanbin Wang, Lijuan Wang, Yan Gong, Tao Guo, Xu Zhao
The enhancement of g-C3N4 photocatalytic degradation of bisphenol A (BPA) via persulfate (PS) addition was investigated under visible light irradiation. The effects of various parameters on the BPA degradation were investigated, such as catalysts dosage, PS concentrations, initial pH value and BPA concentration. The results showed that g-C3N4 nanosheets exhibited superior photocatalytic activity toward BPA degradation as compared with bulk g-C3N4. The addition of PS can further improve the g-C3N4 photocatalytic performance for BPA degradation...
September 4, 2017: Chemosphere
https://www.readbyqxmd.com/read/28934642/physiological-responses-and-gene-expression-changes-in-the-western-mosquitofish-gambusia-affinis-exposed-to-progesterone-at-environmentally-relevant-concentrations
#12
Liping Hou, Hongyan Xu, Guangguo Ying, Yang Yang, Hu Shu, Jianliang Zhao, Xuemei Cheng
Progesterone (P4) is a natural and synthetic steroid, widely distributed in the aquatic environments. It can lead to adverse effects on the endocrine system in aquatic organisms. This study investigated the toxicological effects of exposure to environmentally relevant concentrations (4, 44, and 410ng/L) of progesterone for 42 d on adult female mosquitofish, Gambusia affinis. We performed morphological and histological analyses on gonads, anal fins, liver, and gills after the exposure of mosquito fish to P4...
September 14, 2017: Aquatic Toxicology
https://www.readbyqxmd.com/read/28934638/a-qualitative-study-on-communication-between-nursing-students-and-the-family-members-of-patients
#13
Zenobia C Y Chan
BACKGROUND: When caring for a family as a unit, it is as crucial to communicate with the family members of a patient as it is with the patient. However, there is a lack of research on the views of nursing students on communicating with the family members of patients, and little has been mentioned in the nursing curriculum on this topic. AIM: The aim of this study was to explore nursing students' experiences of communicating with the family members of patients. DESIGN: A qualitative descriptive study...
September 12, 2017: Nurse Education Today
https://www.readbyqxmd.com/read/28934636/museum-based-programs-for-socially-isolated-older-adults-understanding-what-works
#14
Carolyn Todd, Paul M Camic, Bridget Lockyer, Linda J M Thomson, Helen J Chatterjee
This paper presents research findings that help to understand how museum programs created opportunities to enhance wellbeing and health, and changed experiences of social isolation in older adults. The research conceptualized how program elements enabled both individual experiences and relational processes to occur. These components operated within a context that was enriched by the museum as a place to support wellbeing and enhance social interaction. To meaningfully support socially isolated older people as part of local public health strategies, museums need to be accessible and engaging places that purposively support social interaction by involving people and objects, participating in multiple sessions over time, that are facilitated by skilled and knowledgeable staff...
September 18, 2017: Health & Place
https://www.readbyqxmd.com/read/28934623/a-scoping-review-of-human-support-factors-in-the-context-of-internet-based-psychological-interventions-ipis-for-depression-and-anxiety-disorders
#15
REVIEW
Minjung Shim, Brittain Mahaffey, Michael Bleidistel, Adam Gonzalez
Internet-based psychological interventions (IPIs) may provide a highly accessible alternative to in-person psychotherapy. However, little is known about the role of human-support in IPIs for depression and anxiety disorders. The purpose of this study was to evaluate the evidence in the literature regarding the role of human-support in IPIs for depression and anxiety disorders; identify research gaps; and provide recommendations. A scoping review of randomized controlled trials was conducted using seven databases...
September 12, 2017: Clinical Psychology Review
https://www.readbyqxmd.com/read/28934611/enhanced-biodegradation-of-atrazine-by-bacteria-encapsulated-in-organically-modified-silica-gels
#16
Joey J Benson, Jonathan K Sakkos, Adi Radian, Lawrence P Wackett, Alptekin Aksan
Biodegradation by cells encapsulated in silica gel is an economical and environmentally friendly method for the removal of toxic chemicals from the environment. In this work, recombinant E. coli expressing atrazine chlorohydrolase (AtzA) were encapsulated in organically modified silica (ORMOSIL) gels composed of TEOS, silica nanoparticles (SNPs), and either phenyltriethoxysilane (PTES) or methyltriethoxysilane (MTES). ORMOSIL gels adsorbed much higher amounts of atrazine than the hydrophilic TEOS gels. The highest amount of atrazine adsorbed by ORMOSIL gels was 48...
September 11, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28934607/a-visible-light-driven-heterojuncted-composite-wo3-bi12o17cl2-synthesis-characterization-and-improved-photocatalytic-performance
#17
Jiaojiao Zheng, Fei Chang, Mingzhi Jiao, Quan Xu, Baoqing Deng, Xuefeng Hu
Novel visible-light-driven WO3/Bi12O17Cl2 heterojuncted photocatalysts with different mass ratios were successfully fabricated by a facile hydrothermal process and were characterized by XRD, UV-Vis DRS, SEM, TEM, HRTEM, XPS, BET, Raman, PL, and ESR techniques. The original morphology of Bi12O17Cl2 was maintained after the addition of WO3 nanoparticles and the specific surface area values of WBx composites were obviously enlarged. The intimate contact of both components in HRTEM confirmed the generation of smooth phase interface...
September 14, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28934561/epigenetic-mechanisms-regulating-adaptive-responses-to-targeted-kinase-inhibitors-in-cancer
#18
Steven P Angus, Jon S Zawistowski, Gary L Johnson
Although targeted inhibition of oncogenic kinase drivers has achieved remarkable patient responses in many cancers, the development of resistance has remained a significant challenge. Numerous mechanisms have been identified, including the acquisition of gatekeeper mutations, activating pathway mutations, and copy number loss or gain of the driver or alternate nodes. These changes have prompted the development of kinase inhibitors with increased selectivity, use of second-line therapeutics to overcome primary resistance, and combination treatment to forestall resistance...
September 15, 2017: Annual Review of Pharmacology and Toxicology
https://www.readbyqxmd.com/read/28934559/psychological-perspectives-on-interrogation
#19
Aldert Vrij, Christian A Meissner, Ronald P Fisher, Saul M Kassin, Charles A Morgan, Steven M Kleinman
Proponents of "enhanced interrogation techniques" in the United States have claimed that such methods are necessary for obtaining information from uncooperative terrorism subjects. In the present article, we offer an informed, academic perspective on such claims. Psychological theory and research shows that harsh interrogation methods are ineffective. First, they are likely to increase resistance by the subject rather than facilitate cooperation. Second, the threatening and adversarial nature of harsh interrogation is often inimical to the goal of facilitating the retrieval of information from memory and therefore reduces the likelihood that a subject will provide reports that are extensive, detailed, and accurate...
September 1, 2017: Perspectives on Psychological Science: a Journal of the Association for Psychological Science
https://www.readbyqxmd.com/read/28934551/polymer-conjugation-to-enhance-cellulase-activity-and-preserve-thermal-and-functional-stability
#20
Thaiesha A Wright, Melissa Lucius Dougherty, Benjamin Schmitz, Kevin M Burridge, Katherine Makaroff, Jamie M Stewart, Henry D Fischesser, Jerry T Shepherd, Jason A Berberich, Dominik Konkolewicz, Richard C Page
A thermophilic cellulase, FnCel5a, from Fervidobacterium nodosum was conjugated with various functional polymers including cationic, anionic, and strongly and weakly hydrogen bonding polymers. The activity of FnCel5a toward a high molecular weight carboxymethyl cellulose substrate was enhanced by polymer conjugation. Activity enhancements of 50% or greater observed for acrylamide and mixed N,N-dimethyl acrylamide/2-(N,N-dimethylamino)ethyl methacrylate polymers suggesting that the greatest enhancements were caused by polymers capable of non-covalent interactions with the substrate...
September 21, 2017: Bioconjugate Chemistry
keyword
keyword
21783
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"