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Regulation theory

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https://www.readbyqxmd.com/read/28227082/long-term-quasi-continuous-oxygen-saturation-levels-obtained-from-sternal-photoplethysmography-on-patients-with-obstructive-lung-diseases
#1
Shadi S Chreiteh, Dorthe B Saadi, Bo Belhage, Nassim Nabipour, Karsten Hoppe, Erik V Thomsen, Shadi S Chreiteh, Dorthe B Saadi, Bo Belhage, Nassim Nabipour, Karsten Hoppe, Erik V Thomsen, Bo Belhage, Karsten Hoppe, Shadi S Chreiteh, Nassim Nabipour, Erik V Thomsen, Dorthe B Saadi
Calculation of long-term quasi-continuous oxygen saturation (SpO2) levels is highly relevant for critically ill patients. The purpose of this study is therefore to conduct a preliminary investigation of the clinical reliability of long-term photoplethysmography (PPG) recordings obtained from the sternum of patients admitted to the hospital with obstructive lung diseases. Due to the lack of a gold standard reference that is suitable for long-term monitoring without interfering with the patient's activity level, we extracted reliable segments based on knowledge from the basic pulse oximeter theory as well as knowledge about the inherent physiological regulation of the SpO2 levels...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28224241/stem-cell-mechanical-behaviour-modelling-substrate-s-curvature-influence-during-adhesion
#2
M Vassaux, J L Milan
Recent experiments hint that adherent cells are sensitive to their substrate curvature. It is already well known that cells behaviour can be regulated by the mechanical properties of their environment. However, no mechanisms have been established regarding the influence of cell-scale curvature of the substrate. Using a numerical cell model, based on tensegrity structures theory and the non-smooth contact dynamics method, we propose to investigate the mechanical state of adherent cells on concave and convex hemispheres...
February 21, 2017: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/28223491/oogenesis-and-reproductive-investment-of-atlantic-herring-are-functions-of-not-only-present-but-long-ago-environmental-influences-as-well
#3
Thassya C Dos Santos Schmidt, Aril Slotte, James Kennedy, Svein Sundby, Arne Johannessen, Gudmundur J Óskarsson, Yutaka Kurita, Nils C Stenseth, Olav Sigurd Kjesbu
Following general life history theory, immediate reproductive investment (egg mass × fecundity/body mass) in oviparous teleosts is a consequence of both present and past environmental influences. This clarification questions the frequent use of season-independent (general) fecundity formulas in marine fish recruitment studies based on body metrics only. Here we test the underlying assumption of no lag effect on gametogenesis in the planktivorous, determinate-fecundity Atlantic herring (Clupea harengus) displaying large plasticity in egg mass and fecundity, examining Norwegian summer-autumn spawning herring (NASH), North Sea autumn-spawning herring (NSAH), and Norwegian spring-spawning herring (NSSH)...
February 21, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28221139/how-do-stones-form-is-unification-of-theories-on-stone-formation-possible
#4
Victoria Y Bird, Saeed R Khan
There are two basic pathways for formation of calcium based kidney stones. Most idiopathic calcium oxalate (CaOx) stones are formed in association with sub-epithelial plaques of calcium phosphate (CaP), known as Randall's plaques, on renal papillary surfaces. Crystal formation and retention within the terminal collecting ducts, the ducts of Bellini, leading to the formation of Randall's plugs, is the other pathway. Both pathways require supersaturation leading to crystallization, regulated by various crystallization modulators produced in response to changing urinary conditions...
January 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28221048/an-application-of-deviance-regulation-theory-to-reduce-alcohol-related-problems-among-college-women-during-spring-break
#5
Robert D Dvorak, Matthew P Kramer, Brittany L Stevenson, Emily M Sargent, Tess M Kilwein
Spring break (SB) can lead to heavy episodic drinking and increased alcohol-related risks. This may be especially relevant for women. The current study utilized deviance regulation theory to increase the use of protective behavioral strategies (PBSs) among female college students on SB. Female college students going on SB (n = 62) completed a screening, a pre-SB intervention (where they were randomly assigned to receive either a positively or negatively framed message about individuals who do or do not use PBS), and a post-SB assessment that provided alcohol and PBS use data for each day of SB (n = 620 person-days)...
February 20, 2017: Psychology of Addictive Behaviors: Journal of the Society of Psychologists in Addictive Behaviors
https://www.readbyqxmd.com/read/28220123/human-tumor-infiltrating-myeloid-cells-phenotypic-and-functional-diversity
#6
REVIEW
Louise A Elliott, Glen A Doherty, Kieran Sheahan, Elizabeth J Ryan
Our current understanding of human tumor-resident myeloid cells is, for the most part, based on a large body of work in murine models or studies enumerating myeloid cells in patient tumor samples using immunohistochemistry (IHC). This has led to the establishment of the theory that, by and large, tumor-resident myeloid cells are either "protumor" M2 macrophages or myeloid-derived suppressor cells (MDSC). This concept has accelerated our understanding of myeloid cells in tumor progression and enabled the elucidation of many key regulatory mechanisms involved in cell recruitment, polarization, and activation...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28218873/evaluating-internet-based-information-on-physical-activity-for-children-and-youth-with-physical-disabilities
#7
Lauren K Tristani, Rebecca Bassett-Gunter, Sunita Tanna
Parents are an important source of support for facilitating physical activity in children and youth with disabilities (CYWD). Approximately 70% of parents report using the Internet to search for information regarding their children's health. This study examined the theoretical content of physical activity information contained on publicly available Web sites targeting parents of CYWD. Web sites were amassed using Google, a combination of various search terms, and predetermined inclusion criteria. The Web sites were coded and analyzed using the content-analysis approach to the theory of specified persuasive educational communication...
January 2017: Adapted Physical Activity Quarterly: APAQ
https://www.readbyqxmd.com/read/28216800/treatment-of-depression-from-a-self-regulation-perspective-basic-concepts-and-applied-strategies-in-self-system-therapy
#8
Timothy J Strauman, Kari M Eddington
Self-regulation models of psychopathology provide a theory-based, empirically supported framework for developing psychotherapeutic interventions that complement and extend current cognitive-behavioral models. However, many clinicians are only minimally familiar with the psychology of self-regulation. The aim of the present manuscript is twofold. First, we provide an overview of self-regulation as a motivational process essential to well-being and introduce two related theories of self-regulation which have been applied to depression...
February 2017: Cognitive Therapy and Research
https://www.readbyqxmd.com/read/28212487/interactions-between-membranes-and-metaphilic-polypeptide-architectures-with-diverse-sidechain-populations
#9
Michelle W Lee, Ming Han, Guilherme Volpe Bossa, Carly Snell, Ziyuan Song, Haoyu Tang, Lichen Yin, Jianjun Cheng, Sylvio May, Erik Luijten, Gerard C L Wong
At physiological conditions, most proteins or peptides can fold into relatively stable structures that present on their molecular surfaces specific chemical patterns partially smeared out by thermal fluctuations. These nanoscopically defined patterns of charge, hydrogen bonding, and/or hydrophobicity, along with their elasticity and shape stability (folded proteins have Young's moduli of ~1 × 10(8) Pa), largely determine and limit the interactions of these molecules, such as molecular recognition and allosteric regulation...
February 17, 2017: ACS Nano
https://www.readbyqxmd.com/read/28211503/the-enforcement-of-moral-boundaries-promotes-cooperation-and-prosocial-behavior-in-groups
#10
Brent Simpson, Robb Willer, Ashley Harrell
The threat of free-riding makes the marshalling of cooperation from group members a fundamental challenge of social life. Where classical social science theory saw the enforcement of moral boundaries as a critical way by which group members regulate one another's self-interest and build cooperation, moral judgments have most often been studied as processes internal to individuals. Here we investigate how the interpersonal expression of positive and negative moral judgments encourages cooperation in groups and prosocial behavior between group members...
February 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28208380/inferring-hidden-states-in-langevin-dynamics-on-large-networks-average-case-performance
#11
B Bravi, M Opper, P Sollich
We present average performance results for dynamical inference problems in large networks, where a set of nodes is hidden while the time trajectories of the others are observed. Examples of this scenario can occur in signal transduction and gene regulation networks. We focus on the linear stochastic dynamics of continuous variables interacting via random Gaussian couplings of generic symmetry. We analyze the inference error, given by the variance of the posterior distribution over hidden paths, in the thermodynamic limit and as a function of the system parameters and the ratio α between the number of hidden and observed nodes...
January 2017: Physical Review. E
https://www.readbyqxmd.com/read/28207172/drivers-of-redistribution-of-fishing-and-non-fishing-effort-after-the-implementation-of-a-marine-protected-area-network
#12
Reniel B Cabral, Steven D Gaines, Brett A Johnson, Tom W Bell, Crow White
Marine spatial planning (MSP) is increasingly utilized to sustainably manage ocean uses. Marine protected areas (MPAs), a form of spatial management in which parts of the ocean are regulated to fishing, are now a common tool in MSP for conserving marine biodiversity and managing fisheries. However, the use of MPAs in MSP often neglects, or simplifies, the redistribution of fishing and non-fishing activities inside and outside of MPAs following their implementation. This redistribution of effort can have important implications for effective MSP...
October 3, 2016: Ecological Applications: a Publication of the Ecological Society of America
https://www.readbyqxmd.com/read/28206748/regulated-synthesis-of-mo-sheets-and-their-derivative-mox-sheets-x-p-s-c-as-efficient-electrocatalysts-for-hydrogen-evolution-reaction
#13
Jin Jia, Weijia Zhou, Guixiang Li, Linjing Yang, Zhaoqian Wei, Lindie Cao, Yisheng Wu, Kai Zhou, Shaowei Chen
Electrochemical H2 generation from H2O has been focused on the exploration for non-noble-metal as well as earth-rich based catalysts. In our practical work, we put forward a simple cost-efficient fabrication process to prepare massively Mo sheets via the controlled equilibrium between sublimation of MoO3 and reduction of H2. The obtained Mo sheets as Mo source and template synthesize porous MoP sheets, which exhibit notable activity to the hydrogen evolution reaction with a low onset potential of -88 mV vs...
February 16, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28205334/long-non-coding-rna-tug1-promotes-migration-and-invasion-by-acting-as-a-cerna-of-mir-335-5p-in-osteosarcoma-cells
#14
Yong Wang, Tao Yang, Zhen Zhang, Ming Lu, Wei Zhao, Xiandong Zeng, Weiguo Zhang
Long non-coding RNAs (lncRNAs) have now become the new hotspots in an ocean of diseases including osteosarcoma. The function of taurine up-regulated gene 1 (TUG1) and its working mechanism in osteosarcoma remain unclear. In our research, we found that TUG1 was elevated and correlated with a poor prognosis in osteosarcoma patients. Also, the following functional experiment showed that decreased TUG1 could remarkably inhibit osteosarcoma cell migration and invasion, indicating that TUG1 functioned as an oncogene in osteosarcoma...
February 15, 2017: Cancer Science
https://www.readbyqxmd.com/read/28204845/mirnas-target-databases-developmental-methods-and-target-identification-techniques-with-functional-annotations
#15
REVIEW
Nagendra Kumar Singh
PURPOSE: microRNA (miRNA) regulates diverse biological mechanisms and metabolisms in plants and animals. Thus, the discoveries of miRNA has revolutionized the life sciences and medical research.The miRNA represses and cleaves the targeted mRNA by binding perfect or near perfect or imperfect complementary base pairs by RNA-induced silencing complex (RISC) formation during biogenesis process. One miRNA interacts with one or more mRNA genes and vice versa, hence takes part in causing various diseases...
February 15, 2017: Cellular and Molecular Life Sciences: CMLS
https://www.readbyqxmd.com/read/28202588/control-and-regulation-of-pathways-via-negative-feedback
#16
REVIEW
Herbert M Sauro
The biochemical networks found in living organisms include a huge variety of control mechanisms at multiple levels of organization. While the mechanistic and molecular details of many of these control mechanisms are understood, their exact role in driving cellular behaviour is not. For example, yeast glycolysis has been studied for almost 80 years but it is only recently that we have come to understand the systemic role of the multitude of feedback and feed-forward controls that exist in this pathway. In this article, control theory is discussed as an approach to dissect the control logic of complex pathways...
February 2017: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/28199746/a-commentary-on-a-workshop-to-reveal-the-foundational-concepts-of-immune-regulation-i-e-tolerance
#17
Melvin Cohn
A summary of the workshop with its laudatory goal "to reveal the foundational concepts in immunology" was recently published in SJI with an invitation to outsiders to comment. In the end a foundational concept is one upon which we can all agree. This requires debate and meaningful experimentation. The goal of this commentary is to provide some of that. Most of immunology is description of an observation (i.e., a fact). However what ties all the facts together as a discipline is theory or conceptualization that give a general context to observation and predicts the next step...
February 15, 2017: Scandinavian Journal of Immunology
https://www.readbyqxmd.com/read/28195013/betrayal-trauma-in-youth-and-negative-communication-during-a-stressful-task
#18
Vanessa M Jacoby, Elisa Krackow, Joseph R Scotti
Attachment-based theories and related research illustrate that emotion regulation develops in the context of a secure relationship between a child and caregiver. When a secure bond is broken, such as in the context of betrayal trauma, children fail to develop necessary emotion regulation skills which can lead to an array of relational problems. The current study examined the relations between betrayal trauma history, type of communication during a stressful interpersonal laboratory task, and emotion regulation difficulties in a sample of trauma-exposed adolescents...
March 2017: International Journal of Aging & Human Development
https://www.readbyqxmd.com/read/28194773/temperamental-predictors-of-subjective-well-being-from-early-adolescence-to-mid-life-the-role-of-temporal-and-energetic-regulation
#19
Agnieszka Bojanowska, Anna M Zalewska
We investigated links between temperament traits described in Strelau's Regulative Theory of Temperament (Emotional Reactivity, Briskness, Activity, Endurance, Perseveration and Sensory Sensitivity) and subjective well-being (SWB)-Positive Affect, Negative Affect and Life Satisfaction as conceptualised by Diener. Participants representing early (n = 166) and late adolescence (n = 199), early (n = 195) and mid-adulthood (n = 156) filled out Formal Characteristics of Behaviour-Temperament Inventory, Positive and Negative Affect Schedule and Satisfaction with Life Scale...
February 14, 2017: International Journal of Psychology: Journal International de Psychologie
https://www.readbyqxmd.com/read/28193862/differential-modulation-of-global-and-local-neural-oscillations-in-rem-sleep-by-homeostatic-sleep-regulation
#20
Bowon Kim, Bernat Kocsis, Eunjin Hwang, Youngsoo Kim, Robert E Strecker, Robert W McCarley, Jee Hyun Choi
Homeostatic rebound in rapid eye movement (REM) sleep normally occurs after acute sleep deprivation, but REM sleep rebound settles on a persistently elevated level despite continued accumulation of REM sleep debt during chronic sleep restriction (CSR). Using high-density EEG in mice, we studied how this pattern of global regulation is implemented in cortical regions with different functions and network architectures. We found that across all areas, slow oscillations repeated the behavioral pattern of persistent enhancement during CSR, whereas high-frequency oscillations showed progressive increases...
February 13, 2017: Proceedings of the National Academy of Sciences of the United States of America
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